Early view

Jan 26, 2023

Editorials
Article

Contribution of fetal microchimeric cells to maternal wound healing in sickle cell ulcers (224 Online Views)

Mansour Alkobtawi, Maria Sbeih, Karim Souaid, Qui Trung Ngô, Dany Nassar, Hugo Arbes, Henri Guillet, Anoosha Habibi, Pablo Bartolucci, Mathieu Castela, Sélim Aractingi, Bénédicte Oulès

https://doi.org/10.3324/haematol.2022.281140

Review Articles

Articles

Venetoclax and dinaciclib elicit synergistic preclinical efficacy against hypodiploid acute lymphoblastic leukemia (48 Online Views)

Holly Pariury, Joshua Fandel, Stefanie Bachl, Kenny K. Ang, Sarine Markossian, Chris G. Wilson, Benjamin S. Braun, Bogdan Popescu, Margo Wohlfeil, Kyle Beckman, Simayijiang Xirenayi, Ritu P. Roy, Adam B. Olshen, Catherine Smith, Michelle R. Arkin, Mignon L. Loh, Ernesto Diaz-Flores

https://doi.org/10.3324/haematol.2022.281443

Comprehensive in silico and functional studies for classification of EPAS1/HIF2A genetic variants identified in patients with erythrocytosis (44 Online Views)

Valéna Karaghiannis, Darko Maric, Céline Garrec, Nada Maaziz, Alexandre Buffet, Loïc Schmitt, Vincent Antunes, Fabrice Airaud, Bernard Aral, Amandine Le Roy, Sébastien Corbineau, Lamisse Mansour-Hendili, Valentine Lesieur, Antoine Rimbert, Fabien Laporte, Marine Delamare, Minke Rab, Stéphane Bézieau, Bruno Cassinat, Frédéric Galacteros, Anne-Paule Gimenez-Roqueplo, Nelly Burnichon, Holger Cario, Richard van Wijk, Celeste Bento, François Girodon, David Hoogewijs, Betty Gardie

https://doi.org/10.3324/haematol.2022.281698

Duality of Nrf2 in iron-overload cardiomyopathy (40 Online Views)

Enrica Federti, Francesca Vinchi, Iana Iatcenko, Alessandra Ghigo, Alessandro Matte, Serge Cedrick Mbiandjeu Toya, Angela Siciliano, Deborah Chiabrando, Emanuela Tolosano, Steven Zebulon Vance, Veronica Riccardi, Immacolata Andolfo, Manuela Iezzi, Alessia Lamolinara, Achille Iolascon, Lucia De Franceschi

https://doi.org/10.3324/haematol.2022.281995

Therapeutic potential of fetal liver cells transplantation in hemophilia A mice (34 Online Views)

Simone Merlin, Saicharan Akula, Alessia Cottonaro, Tamara Garcia-Leal, Luis Javier Serrano, Ester Borroni, Vakhtang Kalandadze, Rocio Galiano, Chiara Borsotti, Antonio Liras, María José Sanchez, Antonia Follenzi

https://doi.org/10.3324/haematol.2022.282001

Differential inhibition of T cell receptor and STAT5 signalling pathways determines the immunomodulatory effects of dasatinib in chronic phase chronic myeloid leukemia (43 Online Views)

Patrick Harrington, Richard Dillon, Deepti Radia, Philippe Rousselot, Donal P. McLornan, Mark Ong, Anna Green, Alessandro Verde, Farzana Hussain, Kavita Raj, Shahram Kordasti, Claire Harrison, Hugues de Lavallade

https://doi.org/10.3324/haematol.2022.282005

Tislelizumab with gemcitabine and oxaliplatin in patients with relapsed or refractory classic Hodgkin lymphoma: a multicenter phase II trial (296 Online Views)

Kaiyang Ding, Hailing Liu, Jie Ma, Haiyan Yang, Lei Cao, Huihan Wang, Hongling Peng, Wei Shi, Xiaoli Zhao, Wei Wu, Huayuan Zhu, Jianyong Li, Lei Fan

https://doi.org/10.3324/haematol.2022.282266

Letters to the Editor

Case Reports

Omalizumab alleviates pruritus in myeloproliferative neoplasms (30 Online Views)

Anna Ravn Landtblom, Johanna Ungerstedt, Anette Hedlund, Magnus Tobiasson, Stefan Deneberg, Martin Jädersten

https://doi.org/10.3324/haematol.2022.281639

Jan 19, 2023

Articles

The IgG-degrading enzyme, Imlifidase, restores the therapeutic activity of FVIII in inhibitor-positive hemophilia A mice (320 Online Views)

Melissa Bou-Jaoudeh, Sandrine Delignat, Victoria Daventure, Jan Astermark, Hervé Lévesque, Jordan D. Dimitrov, Claire Deligne, Valérie Proulle, Sébastien Lacroix-Desmazes

https://doi.org/10.3324/haematol.2022.281895

The immunomodulatory molecule TIGIT is expressed by chronic lymphocytic leukemia cells and contributes to anergy (124 Online Views)

Francesca Arruga, Marta Rubin, Despoina Papazoglou, Andrea Iannello, Nikolaos Ioannou, Riccardo Moia, Davide Rossi, Gianluca Gaidano, Marta Coscia, Luca Laurenti, Giovanni D’Arena, John N. Allan, Richard R. Furman, Tiziana Vaisitti, Alan G. Ramsay, Silvia Deaglio

https://doi.org/10.3324/haematol.2022.282177

Letters to the Editor

Clinical and molecular response of acute myeloid leukemia harboring non-canonical FLT3 N676K driver mutations to contemporary FLT3 inhibitors (307 Online Views)

Gregory W. Roloff, Frank Wen, Aubrianna Ramsland, Andrew S. Artz, Satyajit Kosuri, Wendy Stock, Olatoyosi Odenike, Richard A. Larson, Hongtao Liu, Lucy A. Godley, Michael J. Thirman, Anand A. Patel, Christopher K. Daugherty, Adam S. DuVall, Mariam T. Nawas, Emily Dworkin, Geoffrey D. Wool, Sandeep Gurbuxani, Carrie Fitzpatrick, Jeremy P. Segal, Peng Wang, Michael W. Drazer

https://doi.org/10.3324/haematol.2022.282148

Treatment patterns and real-world effectiveness of rituximab maintenance in older patients with mantle cell lymphoma: a population-based analysis (526 Online Views)

Mengyang Di, Jessica B. Long, Shalin K. Kothari, Tarsheen Sethi, Amer M. Zeidan, Nikolai A. Podoltsev, Rory M. Shallis, Rong Wang, Xiaomei Ma, Scott F. Huntington

https://doi.org/10.3324/haematol.2022.282252

TIM3, a human acute myeloid leukemia stem cell marker, does not enrich for leukemia-initiating stem cells in B-cell acute lymphoblastic leukemia (120 Online Views)

Clara Bueno, Alba Martínez, Paola Alejandra Romecin, Samanta Romina Zanetti, Ricky Tirtakusuma, Eulalia Genesca, Mireia Camós, Manuel Ramírez-Orellana, Eduardo Anguita, Paola Ballerini, Franco Locatelli, José Luis Fuster, Pablo Menéndez

https://doi.org/10.3324/haematol.2022.282394

Jan 12, 2023

Review Articles

Articles

TAL1 activation in T-Cell acute lymphoblastic leukemia: A novel oncogenic 3’ neoenhancer (256 Online Views)

Charlotte Smith, Ashish Goyal, Dieter Weichenhan, Eric Allemand, Anand Mayakonda, Umut Toprak, Anna Riedel, Estelle Balducci, Manisha Manojkumar, Anastasija Pejkovska, Oliver Mücke, Etienne Sollier, Ali Bakr, Kersten Breuer, Pavlo Lutsik, Olivier Hermine, Salvatore Spicuglia, Vahid Asnafi, Christoph Plass, Aurore Touzart

https://doi.org/10.3324/haematol.2022.281583

E3-ligase TRIM31 regulates hematopoietic stem cell homeostasis and MLL-AF9 leukemia (154 Online Views)

Kai Zhang, Dingdong Liu, Yafei Li, Zhencan Shi, Jun Guo, Chengjiang Gao, Hu Wang, Zhenyu Ju, Daojun Diao

https://doi.org/10.3324/haematol.2022.281955

High rate of durable responses with undetectable minimal residual disease with frontline venetoclax and rituximab in young and fit patients with chronic lymphocytic leukemia and an adverse biologic profile: results of the gimema phase II LLC1518 - 'Veritas' study (275 Online Views)

Francesca R Mauro, Irene Della Starza, Monica Messina, Gianluigi Reda, Livio Trentin, Marta Coscia, Paolo Sportoletti, Lorella Orsucci, Valentina Arena, Gloria Margiotta Casaluci, Roberto Marasca, Roberta Murru, Luca Laurenti, Fiorella Ilariucci, Caterina Stelitano, Donato Mannina, Massimo Massaia, Gian Matteo Rigolin, Lydia Scarfò, Monia Marchetti, Luciano Levato, Monica Tani, Annalisa Arcari, Gerardo Musuraca, Marina Deodato, Piero Galieni, Valeria Belsito Patrizi, Daniela Gottardi, Anna Marina Liberati, Annamaria Giordano, Maria Chiara Molinari, Daniela Pietrasanta, Veronica Mattiello, Andrea Visentin, Candida Vitale, Francesco Albano, Antonino Neri, Lucia Anna De Novi, Maria Stefania De Propris, Mauro Nanni, Ilaria Del Giudice, Anna Guarini, Paola Fazi, Marco Vignetti, Alfonso Piciocchi, Antonio Cuneo, Robin Foà

https://doi.org/10.3324/haematol.2022.282116

Low T-cell proportion in the tumor microenvironment is associated with immune escape and poor survival in diffuse large B-cell lymphoma (181 Online Views)

Joo Y. Song, Mary Nwangwu, Ting-Fang He, Weiwei Zhang, Hany Meawad, Victoria Bedell, Joyce Murata-Collins, Pamela Skrabek, Michel R. Nasr, David Scott, James Godfrey, Peter Lee, Wing C. Chan, Dennis D. Weisenburger, Anamarija M. Perry, Alex F. Herrera

https://doi.org/10.3324/haematol.2022.282265

Jan 5, 2023

Editorials

Letters to the Editor

Long-term treatment with pacritinib on a compassionate use basis in patients with advanced myelofibrosis (264 Online Views)

Claire Harrison, Abdulraheem Yacoub, Bart Scott, Adam Mead, Aaron T. Gerds, Jean-Jacques Kiladjian, Ruben Mesa, Miklos Egyed, Christof Scheid, Valentin Garcia Gutierrez, Jennifer O’Sullivan, Sarah Buckley, Kris Kanellopoulos, John Mascarenhas

https://doi.org/10.3324/haematol.2022.282089

Activity of decitabine combined with all-trans retinoic acid in oligoblastic AML: Results from a randomized 2x2 phase II trial (DECIDER) (153 Online Views)

Christoph Rummelt, Olga Grishina, Claudia Schmoor, Martina Crysandt, Michael Heuser, Katharina S. Götze, Richard F. Schlenk, Konstanze Döhner, Helmut R. Salih, Gerhard Heil, Carsten Müller-Tidow, Wolfram Brugger, Andrea Kündgen, Maike de Wit, Aristoteles Giagounidis, Sebastian Scholl, Andreas Neubauer, Jürgen Krauter, Gesine Bug, Haifa Kathrin Al-Ali, Ralph Wäsch, Heiko Becker, Annette M. May, Justus Duyster, Björn Hackanson, Arnold Ganser, Hartmut Döhner, Michael Lübbert

https://doi.org/10.3324/haematol.2022.282258

Efficacy, safety, and cost of mobilization strategies in multiple myeloma: A prospective observational study (219 Online Views)

Binod Dhakal, Mei-Jei Zhang, Linda J. Burns, Xiaoying Tang, Christa Meyer, Lih-Wen Mau, Ajay K. Nooka, Edward Stadtmauer, Ivana N Micallef, Joseph McGuirk, Luciano Costa, Mark B. Juckett, Nina Shah, Richard E. Champlin, Saad Z. Usmani, Sherif S. Farag, Taiga Nishihori, Vivek Roy, Andrew Bodiford, Yvonne J. Barnes, Edward J. Drea, Parameswaran Hari, Mehdi Hamadani

https://doi.org/10.3324/haematol.2022.282269

Dec 29, 2022

Articles

Effects of nandrolone decanoate on telomere length and clinical outcome in patients with telomeropathies: a prospective trial (281 Online Views)

Diego V. Clé, Luiz Fernando B. Catto, Fernanda Gutierrez-Rodrigues, Flávia S. Donaires, Andre L. Pinto, Barbara A. Santana, Luiz Guilherme Darrigo, Elvis T. Valera, Marcel Koenigkam-Santos, José Baddini-Martinez, Neal S. Young, Edson Z. Martinez, Rodrigo T. Calado

https://doi.org/10.3324/haematol.2022.281808

Letters to the Editor

Covid-19 vaccination in patients with immune-mediated thrombotic thrombocytopenic purpura: a single-referral center experience (116 Online Views)

Silvia Maria Trisolini, Saveria Capria, Andrea Artoni, Ilaria Mancini, Mario Biglietto, Giuseppe Gentile, Flora Peyvandi, Anna Maria Testi

https://doi.org/10.3324/haematol.2022.282311

Dec 22, 2022

Editorials
Article

B and T cell acute lymphoblastic leukemia evade chemotherapy at distinct sites in the bone marrow (516 Online Views)

Malwine J. Barz, Lena Behrmann, Danaëlle Capron, Gabriele Zuchtriegel, Fabio D. Steffen, Leo Kunz, Yang Zhang, Iria Jimenez Vermeerbergen, Blerim Marovca, Moritz Kirschmann, Antonia Zech, César Nombela-Arrieta, Urs Ziegler, Timm Schroeder, Beat Bornhauser, Jean-Pierre Bourquin

https://doi.org/10.3324/haematol.2021.280451

Articles

Adjusted comparison of outcomes between patients from CARTITUDE-1 versus multiple myeloma patients with prior exposure to PI, IMiD and anti-CD38 antibody from the prospective, multinational LocoMMotion study of real-world clinical practice (457 Online Views)

Maria-Victoria Mateos, Katja Weisel, Thomas Martin, Jesús G. Berdeja, Andrzej Jakubowiak, A. Keith Stewart, Sundar Jagannath, Yi Lin, Joris Diels, Francesca Ghilotti, Pushpike Thilakarathne, Nolen J Perualila, Jedelyn Cabrieto, Benjamin Haefliger, Nichola Erler-Yates, Clare Hague, Carolyn C Jackson, Jordan M Schecter, Vadim Strulev, Tonia Nesheiwat, Lida Pacaud, Hermann Einsele, Philippe Moreau

https://doi.org/10.3324/haematol.2022.280482

Reduced platelet glycoprotein Ibα shedding accelerates thrombopoiesis and COX-1 recovery: implications for aspirin dosing regimen (254 Online Views)

Paola Simeone, Rossella Liani, Romina Tripaldi, Sonia Ciotti, Antonio Recchiuti, Vittorio Abbonante, Benedetta Porro, Piero Del Boccio, Augusto di Castelnuovo, Paola Lanuti, Marina Camera, Damiana Pieragostino, Melissa Lee-Sundlov, Myriam Luongo, Raffaella Auciello, Giuseppina Bologna, Maria Concetta Cufaro, Elena Tremoli, Karin M Hoffmeister, Francesco Cipollone, Alessandra Balduini, Francesca Santilli

https://doi.org/10.3324/haematol.2022.281006

Targeting TPO-independent strategy in the discovery of a novel megakaryocytopoiesis inducer DMAG for treatment of thrombocytopenia (192 Online Views)

Long Wang, Sha Liu, Jiesi Luo, Qi Mo, Mei Ran, Ting Zhang, Xiaoxuan Li, Wenjun Zou, Qibing Mei, Jianping Chen, Jing Yang, Jing Zeng, Feihong Huang, Anguo Wu, Chunxiang Zhang, Jianming Wu

https://doi.org/10.3324/haematol.2022.282209

Letters to the Editor

Kaposi sarcoma herpesvirus viral load as a biomarker for leptomeningeal involvement by primary effusion lymphoma (171 Online Views)

Kathryn Lurain, Ramya Ramaswami, Vickie Marshall, Elena M. Cornejo Castro, Nazzarena Labo, Wendell Miley, Kyle Moore, Romin Roshan, Ralph Mangusan, Elaine S. Jaffe, Stefania Pittaluga, Hao-Wei Wang, Mark Roth, Armando C. Filie, Thomas S. Uldrick, Denise Whitby, Robert Yarchoan

https://doi.org/10.3324/haematol.2022.281472

Sex differences in progression of kidney disease in sickle cell disease (127 Online Views)

Kenneth I. Ataga, Qingning Zhou, Santosh L. Saraf, Jane S. Hankins, Emily J. Ciccone, Laura R. Loehr, Melanie E. Garrett, Allison E. Ashley-Koch, Jianwen Cai, Marilyn J. Telen, Vimal K. Derebail

https://doi.org/10.3324/haematol.2022.281677

Allogeneic hematopoietic cell transplant for hairy cell leukemia: EBMT experience (161 Online Views)

Dai Chihara, Luuk Gras, Nienke Zinger, Nicolaus Kröger, Jiri Mayer, Jakob Passweg, Régis Peffault de Latour, Jenny Byrne, William Krüger, Jan-Paul Bohn, Uwe Platzbecker, Igor Wolfgang Blau, Francesca Bonifazi, Grzegorz Helbig, Andrew McDonald, Martin Mistrik, Mohamad Mohty, Ron Ram, Jaime Sanz, Carlos Vallejo Llamas, Robert J. Kreitman, Patrick J. Hayden, Donal McLornan, Olivier Tournilhac, Michel van Gelder, Ibrahim Yakoub-Agha

https://doi.org/10.3324/haematol.2022.281754

End-of-treatment PET in early-stage Hodgkin lymphoma: valuable in addition to interim-PET (141 Online Views)

Karan L. Chohan, Jason R. Young, Scott Lester, Muhamad Alhaj Moustafa, Allison Rosenthal, Han W. Tun, Bradford S. Hoppe, Patrick B. Johnston, Ivana N. Micallef, Thomas M. Habermann, Stephen M. Ansell

https://doi.org/10.3324/haematol.2022.282115

Retrospective analysis of a cohort of 41 de novo B-cell prolymphocytic leukemia patients: impact of genetics and targeted therapies (a FILO study) (167 Online Views)

Caroline Algrin, Louis Pérol, Elise Chapiro, Lucile Baseggio, Karim Maloum, Catherine Settegrana, Jean-François Lesesve, Justine Siavellis, Alain Delmer, Anne-Sophie Michallet, Emmanuelle Ferrant, Pierre Feugier, Cécile Tomowiak, Annie Brion, David Ghez, Luc-Matthieu Fornecker, Sarah Ivanoff, Stéphanie Struski, Laurent Sutton, Isabelle Radford-Weiss, Virginie Eclache, Christine Lefebvre, Véronique Leblond, Florence Nguyen-Khac, Damien Roos-Weil

https://doi.org/10.3324/haematol.2022.282162

Light chain amyloidosis associated with Waldenström macroglobulinemia: treatment and survival outcomes (241 Online Views)

Joshua N. Gustine, Raphael E. Szalat, Andrew Staron, Tracy Joshi, Lisa Mendelson, J. Mark Sloan, Vaishali Sanchorawala

https://doi.org/10.3324/haematol.2022.282264

Clinical and molecular features of familial chronic lymphocytic leukemia: a pilot monocentric study (117 Online Views)

Giulia Benintende, Idanna Innocenti, Alberto Fresa, Francesco Autore, Annamaria Tomasso, Alfonso Piciocchi, Florenzia Vuono, Luca Stirparo, Antonio Mosca, Andrea Bacigalupo, Valter Gattei, Dimitar Efremov, Eugenio Sangiorgi, Luca Laurenti

https://doi.org/10.3324/haematol.2022.282268

Patient-reported fatigue and pain in Erdheim-Chester disease: a registry-based, mixed methods study (140 Online Views)

Anne S. Reiner, Dana Bossert, Justin J. Buthorn, Allison M. Sigler, Selin Gonen, Deanna Fournier, Kathleen Brewer, Jessica Corkran, Gaurav Goyal, Carl E. Allen, Kenneth L. McClain, Thomas M. Atkinson, Kathleen A. Lynch, Jun J. Mao, Katherine S. Panageas, Eli L. Diamond

https://doi.org/10.3324/haematol.2022.282287

IELSG40/CLEO phase II trial of clarithromycin and lenalidomide in relapsed/refractory extranodal marginal zone lymphoma (165 Online Views)

Maria Cristina Pirosa, Marianna Sassone, Barbara Kiesewetter, Armando Lopez Guillermo, Liliana Devizzi, Eva Domingo Domènech, Alessandra Tucci, Donato Mannina, Michele Merli, Antonio Salar, Carlo Visco, Fabiana Esposito, Luisella Bonomini, Emanuele Zucca, Andrés J. M. Ferreri, Markus Raderer

https://doi.org/10.3324/haematol.2022.281963

Case Reports

Dec 15, 2022

Review Articles

Articles

Exome sequencing in 116 patients with inherited thrombocytopenia that remained of unknown origin after systematic phenotype-driven diagnostic workup (221 Online Views)

Caterina Marconi, Alessandro Pecci, Flavia Palombo, Federica Melazzini, Roberta Bottega, Elena Nardi, Valeria Bozzi, Michela Faleschini, Serena Barozzi, Tania Giangregorio, Pamela Magini, Carlo L. Balduini, Anna Savoia, Marco Seri, Patrizia Noris, Tommaso Pippucci

https://doi.org/10.3324/haematol.2022.280993

Overexpression of the key metabolic protein CPT1A defines mantle cell lymphoma patients with poor response to standard high dose chemotherapy independent of MIPI and complement established high-risk factors (164 Online Views)

Anna Sandström Gerdtsson, Joana de Matos Rodrigues, Christian Winther Eskelund, Simon Husby, Kirsten Grønbæk, Riikka Räty, Arne Kolstad, Christian Geisler, Anna Porwit, Mats Jerkeman, Sara Ek

https://doi.org/10.3324/haematol.2022.281420

CCRL2 affects the sensitivity of myelodysplastic syndrome and secondary acute myeloid leukemia cells to azacitidine (282 Online Views)

Theodoros Karantanos, Patric Teodorescu, Marios Arvanitis, Brandy Perkins, Tania Jain, Amy E. DeZern, W. Brian Dalton, Ilias Christodoulou, Bogdan C. Paun, Ravi Varadhan, Christopher Esteb, Trivikram Rajkhowa, Challice Bonifant, Lukasz P. Gondek, Mark J. Levis, Srinivasan Yegnasubramanian, Gabriel Ghiaur, Richard J. Jones

https://doi.org/10.3324/haematol.2022.281444

Ex vivo venetoclax sensitivity testing predicts treatment response in acute myeloid leukemia (812 Online Views)

Heikki Kuusanmäki, Sari Kytölä, Ida Vänttinen, Tanja Ruokoranta, Amanda Ranta, Jani Huuhtanen, Minna Suvela, Alun Parsons, Annasofia Holopainen, Anu Partanen, Milla E.L. Kuusisto, Sirpa Koskela, Riikka Räty, Maija Itälä-Remes, Imre Västrik, Olli Dufva, Sanna Siitonen, Kimmo Porkka, Krister Wennerberg, Caroline A. Heckman, Pia Ettala, Marja Pyörälä, Johanna Rimpiläinen, Timo Siitonen, Mika Kontro

https://doi.org/10.3324/haematol.2022.281692

Letters to the Editor

Pirtobrutinib results in reversible platelet dysfunction compared to ibrutinib and acalabrutinib (311 Online Views)

Alexander P Bye, Neline Kriek, Tanya Sage, Suzannah J Rawlings, Catherine Prodger, Murali Kesavan, Charlotte Lees, Stephen Booth, Louise G Cowen, Kirsty Shefferd, Michael J Desborough, Jonathan M Gibbins, Toby A Eyre

https://doi.org/10.3324/haematol.2022.281402

Thrombin formation via the intrinsic coagulation pathway and von Willebrand factor reflect disease severity in COVID-19 (161 Online Views)

Matthias H. Busch, Sjoerd A.M.E.G. Timmermans, Sander M.J. van Kuijk, Joop P. Aendekerk, Renée Ysermans, Daan P.C. van Doorn, Judith Potjewijd, Marcel C.G. van de Poll, Iwan C.C. van der Horst, Jan G.M.C. Damoiseaux, Henri M.H. Spronk, Hugo ten Cate, Chris P. Reutelingsperger, Magdolna Nagy, Pieter van Paassen

https://doi.org/10.3324/haematol.2022.281693

Combination therapy with crizotinib and vinblastine for relapsed or refractory pediatric ALK-positive anaplastic large cell lymphoma (204 Online Views)

Fabian Knörr, Kim P.J. Schellekens, Reineke A. Schoot, Judith Landman-Parker, Heiko-Manuel Teltschik, Jan Förster, Amambay Riquelme, Alwin D.R. Huitema, Natasha K.A. van Eijkelenburg, Auke Beishuizen, C. Michel Zwaan, Wilhelm Woessmann, Jasper van der Lugt

https://doi.org/10.3324/haematol.2022.281896

Predictors of response to venetoclax plus hypomethylating agent therapy and survival in blast-phase myeloproliferative neoplasm (296 Online Views)

Naseema Gangat, Rimal Ilyas, Kristen McCullough, Kebede H. Begna, Aref Al-Kali, Mrinal M. Patnaik, Mark R. Litzow, William J. Hogan, Abhishek Mangaonkar, Hassan Alkhateeb, Mithun V. Shah, Michelle A. Elliott, James M. Foran, Talha Badar, Jeanne M. Palmer, Curtis A. Hanson, Animesh Pardanani, Ayalew Tefferi

https://doi.org/10.3324/haematol.2022.282019

Dec 7, 2022

Editorials
Article

Allogeneic, Off-the-Shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high risk patients (506 Online Views)

Spyridoula Vasileiou, LaQuisa Hill, Manik Kuvalekar, Aster G. Workineh, Ayumi Watanabe, Yovana Velazquez, Suhasini Lulla, Kimberly Mooney, Natalia Lapteva, Bambi J. Grilley, Helen E. Heslop, Cliona M. Rooney, Malcolm K. Brenner, Todd N. Eagar, George Carrum, Kevin A. Grimes, Ann M. Leen, Premal Lulla

https://doi.org/10.3324/haematol.2022.281946

Articles

Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsuficiency (388 Online Views)

Avigail Rein, Ifat Geron, Eitan Kugler, Hila Fishman, Eyal Gottlieb, Ifat Abramovich, Amir Giladi, Ido Amit, Roger Mulet-Lazaro, Ruud Delwel, Stefan Gröschel, Smadar Levin-Zaidman, Nili Dezorella, Vered Holdengreber, Tata Nageswara Rao, Joanne Yacobovich, Orna Steinberg-Shemer, Qiu-Hua Huang, Yun Tan, Sai-Juan Chen, Shai Izraeli, Yehudit Birger

https://doi.org/10.3324/haematol.2022.279437

Adipocytes control haematopoiesis and inflammation through CD40 signaling (321 Online Views)

Myrthe E. Reiche, Kikkie Poels, Laura A. Bosmans, Winnie G. Vos, Claudia M. van Tiel, Marion J.J. Gijbels, Suzanne A.B.M. Aarts, Myrthe den Toom, Linda Beckers, Christian Weber, Dorothee Atzler, Patrick C.N. Rensen, Sander Kooijman, Esther Lutgens

https://doi.org/10.3324/haematol.2022.281482

Letters to the Editor

Time without transfusion reliance: a novel patient-centric metric for new therapies in myelodysplastic syndromes (369 Online Views)

Joshua F. Zeidner, Flora Mazerolle, Jonathan Norton, Antoine Regnault, Fjoralba Kristo, Heather Romero, Robert J. Fram, Douglas V. Faller, Mehul Dalal, Lionel Ades, Mikkael A. Sekeres

https://doi.org/10.3324/haematol.2022.281856

Pirtobrutinib and venetoclax combination overcomes resistance to targeted and CAR Tcell therapy in aggressive mantle cell lymphoma (395 Online Views)

Yang Liu, Fangfang Yan, Vivian Changying Jiang, Yijing Li, Yuxuan Che, Joseph McIntosh, Alexa Jordan, Ian Hou, Lei Nie, Jingling Jin, Wei Wang, Heng-Huan Lee, Yixin Yao, Michael Wang

https://doi.org/10.3324/haematol.2022.282031

Case Reports

Sirolimus as frontline therapy for PTEN-mutated histiocytic sarcoma (227 Online Views)

Karan L. Chohan, Jithma P. Abeykoon, Jason R. Young, W. Oliver Tobin, Mathew J. Koster, Mithun V. Shah, Jay H. Ryu, Robert Vassallo, Karen L. Rech., Aishwarya Ravindran, Gaurav Goyal, Ronald S. Go, N. Nora Bennani

https://doi.org/10.3324/haematol.2022.282207

Dec 1, 2022

Editorials
Article

ALK-negative anaplastic large cell lymphoma with DUSP22 rearrangement has distinctive disease characteristics with better progression-free survival: a LYSA study (326 Online Views)

David Sibon, Bettina Bisig, Christophe Bonnet, Elsa Poullot, Emmanuel Bachy, Doriane Cavalieri, Virginie Fataccioli, Cloe Bregnard, Fanny Drieux, Julie Bruneau, Francois Lemonnier, Aurelie Dupuy, Celine Bossard, Marie Parrens, Krimo Bouabdallah, Nicolas Ketterer, Gregoire Berthod, Anne Cairoli, Gandhi Damaj, Olivier Tournilhac, Jean-Philippe Jais, Philippe Gaulard, Laurence de Leval

https://doi.org/10.3324/haematol.2022.281442
Article

DUSP22 rearrangement is associated with distinctive immunophenotype but not outcome in patients with systemic ALK-negative anaplastic large cell lymphoma (242 Online Views)

Lianqun Qiu, Guilin Tang, Shaoying Li, Francisco Vega, Pei Lin, Sa A. Wang, Wei Wang, Swaminathan P. Iyer, Luis Malpica, Roberto N. Miranda, Sergej Konoplev, Zhenya Tang, Hong Fang, L. Jeffrey Medeiros, Jie Xu

https://doi.org/10.3324/haematol.2022.281222

Editorials
Article

Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on Cytomegalovirus reactivation risk after allogeneic hematopoietic stem cell transplantation (603 Online Views)

Elena Tassi, Maddalena Noviello, Pantaleo De Simone, Maria T. Lupo-Stanghellini, Matteo Doglio, Francesca Serio, Danilo Abbati, Valeria Beretta, Veronica Valtolina, Giacomo Oliveira, Sara Racca, Edoardo Campodonico, Eliana Ruggiero, Daniela Clerici, Fabio Giglio, Francesca Lorentino, Roee Dvir, Elisabetta Xue, Francesca Farina, Chiara Oltolini, Francesco Manfredi, Luca Vago, Consuelo Corti, Massimo Bernardi, Massimo Clementi, Liselotte Brix, Fabio Ciceri, Jacopo Peccatori, Raffaella Greco, Chiara Bonini

https://doi.org/10.3324/haematol.2022.280685

Editorials

Editorials
Article

Targeting glutaminase is therapeutically effective in ibrutinib-resistant mantle cell lymphoma (305 Online Views)

Lingzhi Li, Lei Nie, Alexa Jordan, Qingsong Cai, Yang Liu, Yijing Li, Yuxuan Che, Jovanny Vargas, Zhihong Chen, Angela Leeming, Wei Wang, Yixin Yao, Michael Wang, Vivian Changying Jiang

https://doi.org/10.3324/haematol.2022.281538

Articles

Immune thrombotic thrombocytopenic purpura plasmas induce calcium- and IgG-dependent endothelial activation: correlations with disease severity (191 Online Views)

Edwige Tellier, Agnès Widemann, Raphaël Cauchois, Julien Faccini, Marie Lagarde, Marion Brun, Philippe Robert, Stéphane Robert, Richard Bachelier, Pascale Poullin, Elien Roose, Karen Vanhoorelbeke, Paul Coppo, Françoise Dignat-George, Gilles Kaplanski

https://doi.org/10.3324/haematol.2022.280651

Letters to the Editor

Targeting cytokine-induced leukemic stem cell persistence in chronic myeloid leukemia by IKK2-inhibition (234 Online Views)

Marlena Bütow, Fabio J. Testaquadra, Julian Baumeister, Tiago Maié, Nicolas Chatain, Timo Jaquet, Stefan Tillmann, Martina Crysandt, Ivan G. Costa, Tim H. Brümmendorf, Mirle Schemionek

https://doi.org/10.3324/haematol.2022.280922

Nov 24, 2022

Articles

Hyperactive CREB subpopulations increase during therapy in paediatric B lineage acute lymphoblastic leukaemia (235 Online Views)

Dino Masic, Kayleigh Fee, Hayden Bell, Marian Case, Gabby Witherington, Sophie Lansbury, Juan Ojeda-Garcia, David McDonald, Claire Schwab, Frederik W. van Delft, Andrew Filby, Julie Anne Elizabeth Irving

https://doi.org/10.3324/haematol.2022.281177

Targeting glutaminase is therapeutically effective in ibrutinib-resistant mantle cell lymphoma (305 Online Views)

Lingzhi Li, Lei Nie, Alexa Jordan, Qingsong Cai, Yang Liu, Yijing Li, Yuxuan Che, Jovanny Vargas, Zhihong Chen, Angela Leeming, Wei Wang, Yixin Yao, Michael Wang, Vivian Changying Jiang

https://doi.org/10.3324/haematol.2022.281538

Letters to the Editor

Landscape of immunoglobulin heavy chain gamma gene class switch recombination in patients with adult T-cell leukemia–lymphoma (207 Online Views)

Hiroaki Hiramatsu, Kisato Nosaka, Shigeru Kusumoto, Nobuaki Nakano, Ilseung Choi, Makoto Yoshimitsu, Yoshitaka Imaizumi, Michihiro Hidaka, Hidenori Sasaki, Junya Makiyama, Eiichi Ohtsuka, Tatsuro Jo, Masao Ogata, Asahi Ito, Kentaro Yonekura, Hiro Tatetsu, Takeharu Kato, Toshiro Kawakita, Youko Suehiro, Kenji Ishitsuka, Shinsuke Iida, Takaji Matsutani, Hiroyoshi Nishikawa, Atae Utsunomiya, Ryuzo Ueda, Takashi Ishida

https://doi.org/10.3324/haematol.2022.281435

Nov 17, 2022

Editorials
Article

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through inhibition of autophagy (633 Online Views)

Weiguo Zhang, Guopan Yu, Hongying Zhang, Mahesh Basyal, Charlie Ly, Bin Yuan, Vivian Ruvolo, Sujan Piya, Seemana Bhattacharya, Qi Zhang, Gautam Borthakur, Venkata Battula, Marina Konopleva, William G. Rice, Michael Andreeff

https://doi.org/10.3324/haematol.2022.280884

Editorials
Letter to the Editor

Age- and gender-matched controls needed for platelet-based biomarker studies (222 Online Views)

Siamack Sabrkhany, Marijke J.E. Kuijpers, Sander M.J. van Kuijk, Arjan W. Griffioen, Mirjam G.A. oude Egbrink

https://doi.org/10.3324/haematol.2022.281726

Review Articles

Animal models of Diamond-Blackfan anemia: updates and challenges (821 Online Views)

Y. Lucy Liu, Aya Shibuya, Bert Glader, Mark C. Wilkes, Maria Barna, Kathleen M. Sakamoto

https://doi.org/10.3324/haematol.2022.282042

Articles

Diffuse large B-cell lymphoma in octogenarians aged 85 and older can benefit from treatment with curative intent: a report on 129 patients prospectively registered in the Elderly Project of the Fondazione Italiana Linfomi (FIL) (893 Online Views)

Alessandra Tucci, Francesco Merli, Alberto Fabbri, Luigi Marcheselli, Chiara Pagani, Benedetta Puccini, Dario Marino, Manuela Zanni, Elsa Pennese, Leonardo Flenghi, Annalisa Arcari, Barbara Botto, Melania Celli, Caterina Mammi, Alessandro Re, Giulia Campostrini, Agostino Tafuri, Vittorio R. Zilioli, Emanuele Cencini, Roberto Sartori, Chiara Bottelli, Michele Merli, Luigi Petrucci, Guido Gini, Monica Balzarotti, Federica Cavallo, Gerardo Musuraca, Stefano Luminari, Giuseppe Rossi, Michele Spina

https://doi.org/10.3324/haematol.2022.281407

Letters to the Editor

Dysfunctional subsets of CD39+ T cells, distinct from PD-1+, driven by leukemic extracellular vesicles in myeloid leukemias (952 Online Views)

Julian Swatler, Domenico Lo Tartaro, Rebecca Borella, Marta Brewinska-Olchowik, Annamaria Paolini, Anita Neroni, Laura Turos-Korgul, Milena Wiech, Ewa Kozlowska, Dominik Cysewski, Wioleta Grabowska-Pyrzewicz, Urszula Wojda, Grzegorz Basak, Rafael J. Argüello, Andrea Cossarizza, Sara De Biasi, Katarzyna Piwocka

https://doi.org/10.3324/haematol.2022.281713

Axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma patients in complete metabolic response (300 Online Views)

Andrew P. Jallouk, Sushanth Gouni, Jason Westin, Lei Feng, Haleigh Mistry, Raphael E. Steiner, Jinsu James, Mansoor Noorani, Sandra Horowitz, Nahum Puebla-Osorio, Luis E. Fayad, Swaminathan P. Iyer, Misha Hawkins, Christopher R. Flowers, Sairah Ahmed, Loretta J. Nastoupil, Partow Kebriaei, Elizabeth J. Shpall, Sattva S. Neelapu, Yago Nieto, Paolo Strati

https://doi.org/10.3324/haematol.2022.281954

Case Reports

Clinical response to dabrafenib and chemotherapy in clonally-related histiocytosis and acute lymphoblastic leukemia (826 Online Views)

Gervaise Hubert, Henrique Bittencourt, Caroline Laverdière, Pierre Teira, Sonia Cellot, Sylvie Langlois, Alexandre Rouette, Thomas Sontag, Daniel Sinnett, Dorothée Dal-Soglio, Sophie Turpin, Thai Hoa Tran

https://doi.org/10.3324/haematol.2022.281926

Nov 10, 2022

Articles

Allogeneic, Off-the-Shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high risk patients (506 Online Views)

Spyridoula Vasileiou, LaQuisa Hill, Manik Kuvalekar, Aster G. Workineh, Ayumi Watanabe, Yovana Velazquez, Suhasini Lulla, Kimberly Mooney, Natalia Lapteva, Bambi J. Grilley, Helen E. Heslop, Cliona M. Rooney, Malcolm K. Brenner, Todd N. Eagar, George Carrum, Kevin A. Grimes, Ann M. Leen, Premal Lulla

https://doi.org/10.3324/haematol.2022.281946

Contribution of fetal microchimeric cells to maternal wound healing in sickle cell ulcers (224 Online Views)

Mansour Alkobtawi, Maria Sbeih, Karim Souaid, Qui Trung Ngô, Dany Nassar, Hugo Arbes, Henri Guillet, Anoosha Habibi, Pablo Bartolucci, Mathieu Castela, Sélim Aractingi, Bénédicte Oulès

https://doi.org/10.3324/haematol.2022.281140

Letters to the Editor

Identification of multiple genetic loci associated with RBC alloimmunization in mice (674 Online Views)

Arijita Jash, Heather L. Howie, Ariel M. Hay, Chance John Luckey, Krystalyn E. Hudson, Peter C. Thomson, Sarah J. Ratcliffe, Mark Smolkin, James C. Zimring

https://doi.org/10.3324/haematol.2022.281767

Longitudinal analysis of the evolution of cellular immunity to SARS-CoV-2 induced by infection and vaccination (765 Online Views)

Spyridoula Vasileiou, Manik Kuvalekar, Yovana Velazquez, Ayumi Watanabe, Mansi Narula, Aster G. Workineh, Matthew French-Kim, Alejandro Torres Chavez, Sarah Gilmore, Cliona M. Rooney, Ann M. Leen

https://doi.org/10.3324/haematol.2022.281947

Perspective Articles

Nov 3, 2022

Articles

B and T cell acute lymphoblastic leukemia evade chemotherapy at distinct sites in the bone marrow (516 Online Views)

Malwine J. Barz, Lena Behrmann, Danaëlle Capron, Gabriele Zuchtriegel, Fabio D. Steffen, Leo Kunz, Yang Zhang, Iria Jimenez Vermeerbergen, Blerim Marovca, Moritz Kirschmann, Antonia Zech, César Nombela-Arrieta, Urs Ziegler, Timm Schroeder, Beat Bornhauser, Jean-Pierre Bourquin

https://doi.org/10.3324/haematol.2021.280451

Genomics improves risk stratification of adults with T-cell acute lymphoblastic leukemia patients enrolled in measurable residual disease-oriented trials (546 Online Views)

Celia González-Gil, Mireia Morgades, Thaysa Lopes, Francisco Fuster-Tormo, Jesús García-Chica, Ran Zhao, Pau Montesinos, Anna Torrent, Marina Diaz-Beya, Rosa Coll, Lourdes Hermosín, Santiago Mercadal, José González-Campos, Lurdes Zamora, Teresa Artola, Ferran Vall-Llovera, Mar Tormo, Cristina Gil-Cortés, Pere Barba, Andrés Novo, Jordi Ribera, Teresa Bernal, Paula López de Ugarriza, María-Paz Queipo, Pilar Martínez-Sánchez, Alicia Giménez, Teresa González-Martínez, Antonia Cladera, José Cervera, Rosa Fernández-Martín, María Ángeles Ardaiz, María Jesús Vidal, Ángela Baena, Nuria López-Bigas, Anna Bigas, Jaroslaw Maciejewski, Alberto Orfao, Josep Maria Ribera, Eulalia Genescà

https://doi.org/10.3324/haematol.2022.281196

An objective assessment in newly diagnosed multiple myeloma to avoid treatment complications and strengthen therapy adherence (217 Online Views)

Maximilian Holler, Gabriele Ihorst, Heike Reinhardt, Amelie Rösner, Magdalena Braun, Mandy-Deborah Möller, Esther Dreyling, Katja Schoeller, Sophia Scheubeck, Ralph Wäsch, Monika Engelhardt

https://doi.org/10.3324/haematol.2022.281489

Letters to the Editor

Delayed hemolytic transfusion reaction in children with sickle cell disease: first five-year retrospective study in mainland France (195 Online Views)

Claire Falguière, Slimane Allali, Bassem Khazem, Annie Kamdem, Cécile Arnaud, Marie Belloy, Corinne Guitton, Marie-Hélène Odièvre, Sophie Pertuisel, Cecile Dumesnil, Cécile Guillaumat, Nathalie Garrec, Alexandra Gauthier, Perrine Mahe, Valerie Soussan-Banini, Laure Le-Carrer, Etienne Merlin, Audrey David, Beatrice Pellegrino, Catherine Paillard, Jean-Francois Brasme, Marie Lagarde, France Pirenne, Corinne Pondarre

https://doi.org/10.3324/haematol.2022.281050

Prognostic impact of pre-treatment immunoglobulin clonal composition in pediatric Blymphoblastic leukemia (200 Online Views)

Carol Fries, Lik Wee Lee, Meenakshi Devidas, Yunfeng Dai, Karen R. Rabin, Sumit Gupta, Mignon L. Loh, Ilan R Kirsch, Brent Wood, Rachel E. Rau

https://doi.org/10.3324/haematol.2022.281146

Unique pathologic features and gene expression signatures distinguish blastoid high-grade B-cell lymphoma from B acute lymphoblastic leukemia/lymphoma (222 Online Views)

Lianqun Qiu, Jie Xu, Pei Lin, Evan N. Cohen, Guilin Tang, Sa A. Wang, Mahsa Khanlari, Wei Wang, Joseph D. Khoury, Sergej Konoplev, C. Cameron Yin, Jeffrey L. Jorgensen, Francisco Vega, L. Jeffrey Medeiros, Shaoying Li

https://doi.org/10.3324/haematol.2022.281646

Oct 27, 2022

Editorials
Article

Improved survival in myeloma patients– a nationwide registry study of 4647 patients ≥75 years treated in Denmark and Sweden (389 Online Views)

Kari Lenita Falck Moore, Ingemar Turesson, Anna Genell, Tobias W. Klausen, Dorota Knut-Bojanowska, Louise Redder, Ingigerdur Sverrisdottir, Jonathan Thorsen, Annette J. Vangsted, Cecilie H. Blimark

https://doi.org/10.3324/haematol.2021.280424

Letters to the Editor

International multicentre retrospective analysis of thiotepa-based autologous stem cell transplantation for secondary central nervous system lymphoma (443 Online Views)

Jahanzaib Khwaja, Amy A. Kirkwood, Lisa K. Isbell, Sara Steffanoni, Harshita Goradia, Lisa Pospiech, Thomas Fail, Emma Nicholson, Kate Fletcher, Kim M. Linton, Katrina E. Parsons, Nagah Elmusharaf, Lydia Eccersley, Toby A. Eyre, Sridhar Chaganti, Jeffrey Smith, Nisha Thakrar, Alexandra Kutilina, Teresa Calimeri, Nicolas Martinez-Calle, Dima El-Sharkawi, Wendy Osborne, Gerald Illerhaus, Christopher P. Fox, Andrés J.M. Ferreri, Elisabeth Schorb, Kate Cwynarski

https://doi.org/10.3324/haematol.2022.281640

Oct 20, 2022

Editorials
Article

Pathology review identifies frequent misdiagnoses in recurrent classic Hodgkin lymphoma in a nation-wide cohort: Implications for clinical and epidemiological studies (334 Online Views)

Max V. Boot, Michael Schaapveld, Esther C. van den Broek, Nathalie J. Hijmering, PALGA Group, Kimberly van der Oord, Flora E. van Leeuwen, Avinash G. Dinmohamed, Lianne Koens, Daphne de Jong

https://doi.org/10.3324/haematol.2022.280840

Review Articles

Articles

Three-year results from phase 1 of ZUMA-4: KTE-X19 in pediatric relapsed/refractory acute lymphoblastic leukemia (657 Online Views)

Alan S. Wayne, Van Huynh, Nobuko Hijiya, Rayne H. Rouce, Patrick A. Brown, Joerg Krueger, Carrie L. Kitko, Edward Dela Ziga, Michelle L. Hermiston, Michael K. Richards, Andre Baruchel, Petra C. Schuberth, John Rossi, Lang Zhou, Lovely Goyal, Rajul Jain, Remus Vezan, Behzad Kharabi Masouleh, Daniel W. Lee

https://doi.org/10.3324/haematol.2022.280678

Treatment patterns and outcomes in relapsed/refractory follicular lymphoma: results from the international SCHOLAR-5 study (665 Online Views)

Paola Ghione, M Lia Palomba, Hervé Ghesquieres, Sabela Bobillo, Anik R Patel, Myrna Nahas, Steve Kanters, Kevin Deighton, Anthony Hatswell, Long Ma, Eve H. Limbrick-Oldfield, Julia Thornton Snider, Sally W. Wade, Maria Teresa Riberio, John Radford, Sara Beygi, John Gribben

https://doi.org/10.3324/haematol.2022.281421

Enhancing regulatory T cell function via inhibition of high mobility group box 1 protein signaling in immune thrombocytopenia (685 Online Views)

Haoyi Wang, Tianshu Yu, Ning An, Yunqi Sun, Pengcheng Xu, Panpan Han, Yajing Zhao, Lingjun Wang, Xiaofei Ni, Yubin Li, Guosheng Li, Yanfeng Liu, Jun Peng, Ming Hou, Yu Hou

https://doi.org/10.3324/haematol.2022.281557

Letters to the Editor

Prognostic value of positron emission tomography/computed tomography in transplant-eligible newly diagnosed multiple myeloma patients from CASSIOPEIA: the CASSIOPET study (422 Online Views)

Françoise Kraeber-Bodéré, Sonja Zweegman, Aurore Perrot, Cyrille Hulin, Denis Caillot, Thierry Facon, Xavier Leleu, Karim Belhadj, Emmanuel Itti, Lionel Karlin, Clément Bailly, Mark-David Levin, Monique C. Minnema, Bastien Jamet, Caroline Bodet-Milin, Bart de Keizer, Marie C. Béné, Hervé Avet-Loiseau, Pieter Sonneveld, Lixia Pei, Fabio Rigat, Carla de Boer, Jessica Vermeulen, Tobias Kampfenkel, Jérôme Lambert, Philippe Moreau

https://doi.org/10.3324/haematol.2021.280051

Cytomegalovirus reactivation after CD19 CAR T-cell therapy is clinically significant (445 Online Views)

George Chen, Megan Herr, Jan Nowak, Christine Ho, Nikolaos Almyroudis, Kristopher Attwood, John Bonnewell, Marissa Walsh, Brahm Segal, Maureen Ross, Philip McCarthy, Theresa Hahn

https://doi.org/10.3324/haematol.2022.281719

Oct 13, 2022

Editorials
Letter to the Editor

Clonal hematopoiesis by DNMT3A mutations as a common finding in idiopathic splanchnic vein thrombosis (307 Online Views)

Giovanna Carrà, Emilia Giugliano, Sofia Camerlo, Giorgio Rosati, Enrica Branca, Beatrice Maffeo, Isabella Russo, Rocco Piazza, Daniela Cilloni, Alessandro Morotti

https://doi.org/10.3324/haematol.2022.281705

Editorials

Articles

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through inhibition of autophagy (633 Online Views)

Weiguo Zhang, Guopan Yu, Hongying Zhang, Mahesh Basyal, Charlie Ly, Bin Yuan, Vivian Ruvolo, Sujan Piya, Seemana Bhattacharya, Qi Zhang, Gautam Borthakur, Venkata Battula, Marina Konopleva, William G. Rice, Michael Andreeff

https://doi.org/10.3324/haematol.2022.280884

Variation and impact of polygenic hematological traits in monogenic sickle cell disease (466 Online Views)

Thomas Pincez, Ken Sin Lo, Anne-Laure Pham Hung d’Alexandry d’Orengiani, Melanie E. Garrett, Carlo Brugnara, Allison E. Ashley-Koch, Marilyn J. Telen, Frederic Galacteros, Philippe Joly, Pablo Bartolucci, Guillaume Lettre

https://doi.org/10.3324/haematol.2022.281180

A phase Ib trial of mivavotinib (TAK-659), a dual SYK/FLT3 inhibitor, in patients with relapsed/refractory acute myeloid leukemia (396 Online Views)

Keith W. Pratz, Jason Kaplan, Moshe Levy, Dale Bixby, Patrick W. Burke, Harry Erba, Trisha M. Wise-Draper, Gail J. Roboz, Nikolaos Papadantonakis, Trivikram Rajkhowa, Daniela Hernandez, Iwona Dobler, Richard C. Gregory, Cheryl Li, Shining Wang, Kate Stumpo, Karuppiah Kannan, Harry Miao, Mark Levis

https://doi.org/10.3324/haematol.2022.281216

Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation (620 Online Views)

Yvonne J. Thus, Martin F.M. de Rooij, Nathalie Swier, Roderick L. Beijersbergen, Jeroen E.J. Guikema, Marie-José Kersten, Eric Eldering, Steven T. Pals, Arnon P. Kater, Marcel Spaargaren

https://doi.org/10.3324/haematol.2022.281668

Letters to the Editor

Influence of bisphosphonates or recombinant human parathyroid hormone on in vitro chemotherapy sensitivity of acute lymphoblastic leukemia cells (215 Online Views)

Demi T.C. de Winter, Jenneke E. van Atteveld, Jessica G.C.A.M. Buijs-Gladiness, Rob Pieters, Sebastian J.C.M.M. Neggers, Jules P.P. Meijerink, Marry M. van den Heuvel-Eibrink

https://doi.org/10.3324/haematol.2022.281033

Case Reports

Leon's helmet (187 Online Views)

Hugo Gonzalez, Alice Marceau-Renaut, Marc Spentchian, Maen Hassoun, Geoffroy Guignedoux

https://doi.org/10.3324/haematol.2022.281125

Oct 6, 2022

Articles

CD56brightCD16 natural killer cells as an important regulatory mechanism in chronic graft-versus-host disease (639 Online Views)

Madeline Lauener, Shima AzadPour, Sayeh Abdossamadi, Vaishnavi Parthasarathy, Bernard Ng, Elena Ostroumov, Geoffrey D.E. Cuvelier, Megan K. Levings, Katherine N. MacDonald, Amina Kariminia, Kirk R. Schultz

https://doi.org/10.3324/haematol.2022.280653

Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on Cytomegalovirus reactivation risk after allogeneic hematopoietic stem cell transplantation (603 Online Views)

Elena Tassi, Maddalena Noviello, Pantaleo De Simone, Maria T. Lupo-Stanghellini, Matteo Doglio, Francesca Serio, Danilo Abbati, Valeria Beretta, Veronica Valtolina, Giacomo Oliveira, Sara Racca, Edoardo Campodonico, Eliana Ruggiero, Daniela Clerici, Fabio Giglio, Francesca Lorentino, Roee Dvir, Elisabetta Xue, Francesca Farina, Chiara Oltolini, Francesco Manfredi, Luca Vago, Consuelo Corti, Massimo Bernardi, Massimo Clementi, Liselotte Brix, Fabio Ciceri, Jacopo Peccatori, Raffaella Greco, Chiara Bonini

https://doi.org/10.3324/haematol.2022.280685

Oral HDAC inhibitor tucidinostat in patients with relapsed or refractory peripheral T-cell lymphoma: phase IIb results (1292 Online Views)

Shinya Rai, Won Seog Kim, Kiyoshi Ando, Ilseung Choi, Koji Izutsu, Norifumi Tsukamoto, Masahiro Yokoyama, Kunihiro Tsukasaki, Junya Kuroda, Jun Ando, Michihiro Hidaka, Youngil Koh, Hirohiko Shibayama, Toshiki Uchida, Deok Hwan Yang, Kenji Ishitsuka, Kenichi Ishizawa, Jin Seok Kim, Hong Ghi Lee, Hironobu Minami, Hyeon Seok Eom, Mitsutoshi Kurosawa, Jae Hoon Lee, Jong Seok Lee, Won Sik Lee, Hirokazu Nagai, Takero Shindo, Dok Hyun Yoon, Shinichiro Yoshida, Mireille Gillings, Hiroshi Onogi, Kensei Tobinai

https://doi.org/10.3324/haematol.2022.280996

Lenalidomide-based triplet regimens in first relapsed multiple myeloma patients: real-world evidence from a propensity score matched analysis (634 Online Views)

Silvia Mangiacavalli, Claudio Salvatore Cartia, Monica Galli, Sara Pezzatti, Angelo Belotti, Francesca Fazio, Roberto Mina, Magda Marcatti, Anna Cafro, Renato Zambello, Laura Paris, Gregorio Barilà, Cecilia Olivares, Alessandra Pompa, Rita Mazza, Francesca Farina, Martina Soldarini, Pietro Benvenuti, Giuseppina Pagani, Michele Palumbo, Valeria Masoni, Virginia Valeria Ferretti, Catherine Klersy, Luca Arcaini, Maria Teresa Petrucci

https://doi.org/10.3324/haematol.2022.281342

Development and manufacturing of novel locally produced anti-BCMA CART cells for the treatment of relapsed/refractory multiple myeloma: phase I clinical results (1587 Online Views)

Nathalie Asherie, Shlomit Kfir-Erenfeld, Batia Avni, Miri Assayag, Tatyana Dubnikov, Nomi Zalcman, Eyal Lebel, Eran Zimran, Adir Shaulov, Marjorie Pick, Yael Cohen, Irit Avivi, Cyrille Cohen, Moshe E. Gatt, Sigal Grisariu, Polina Stepensky

https://doi.org/10.3324/haematol.2022.281628

Letters to the Editor

Mutations in the RACGAP1 gene cause autosomal recessive congenital dyserythropoietic anemia type III (319 Online Views)

Gonzalo Hernández, Lídia Romero-Cortadellas, Xènia Ferrer-Cortès, Veronica Venturi, Mercedes Dessy-Rodriguez, Mireia Olivella, Ammar Husami, Concepción Pérez de Soto, Rosario M. Morales-Camacho, Ana Villegas, Fernando-Ataulfo González-Fernández, Marta Morado, Theodosia A. Kalfa, Oscar Quintana-Bustamante, Santiago Pérez-Montero, Cristian Tornador, Jose-Carlos Segovia, Mayka Sánchez

https://doi.org/10.3324/haematol.2022.281277

Impact of daratumumab-based induction on stem cell collection parameters in Swedish myeloma patients (371 Online Views)

Konstantinos Lemonakis, Love Tatting, Mikael Lisak, Kristina Carlson, Jacob Crafoord, Cecilie H Blimark, Antonio I Santamaria, Stina Wichert, Stig Lenhoff, Markus Hansson

https://doi.org/10.3324/haematol.2022.281610

Age- and gender-matched controls needed for platelet-based biomarker studies (222 Online Views)

Siamack Sabrkhany, Marijke J.E. Kuijpers, Sander M.J. van Kuijk, Arjan W. Griffioen, Mirjam G.A. oude Egbrink

https://doi.org/10.3324/haematol.2022.281726

Associations between socioeconomic status and bispecific LV20.19 CAR T-cell therapy outcomes (333 Online Views)

Jennifer M. Knight, Edward Hackett, Aniko Szabo, Ruizhe Wu, Garrett Sauber, Bryon Johnson, Rachel N. Cusatis, Elizabeth Aughey, Steve W. Cole, Cecilia J. Hillard, Nirav N. Shah

https://doi.org/10.3324/haematol.2022.281957

Comments

Sep 29, 2022

Editorials
Article

Heterogeneity in long term outcomes for R-ISS stage II in newly diagnosed multiple myeloma patients (413 Online Views)

Anais Schavgoulidze, Valerie Lauwers-Cances, Aurore Perrot, Titouan Cazaubiel, Marie-Lorraine Chretien, Philippe Moreau, Thierry Facon, Xavier Leleu, Lionel Karlin, Anne-Marie Stoppa, Olivier Decaux, Karim Belhadj, Bertrand Arnulf, Mohamad Mohty, Clara M ariette, Cecile Fohrer-Sonntag, Pascal Lenain, Jean-Pierre Marolleau, Mourad Tiab, Carla Araujo, Frederique Orsini-Piocelle, Arnaud Jaccard, Murielle Roussel, Lotfi Benboubker, Jean-Richard Eveillard, Mamoun Dib, Marion Divoux, Michel Attal, Herve Avet-Loiseau, Jill Corre

https://doi.org/10.3324/haematol.2021.280566

Articles

Plasminogen activator-coated nanobubbles targeting cell-bound β2-glycoprotein I as a novel thrombus-specific thrombolytic strategy (344 Online Views)

Paolo Macor, Paolo Durigutto, Monica Argenziano, Kate Smith-Jackson, Sara Capolla, Valeria Di Leonardo, Kevin Marchbank, Valerio Stefano Tolva, Fabrizio Semeraro, Concetta T. Ammollo, Mario Colucci, Roberta Cavalli, Pierluigi Meroni, Francesco Tedesco

https://doi.org/10.3324/haematol.2022.281505

Comments

Sep 22, 2022

Articles

Genome-wide CRISPR screens identify ferroptosis as a novel therapeutic vulnerability in acute lymphoblastic leukemia (652 Online Views)

Marie-Eve Lalonde, Marc Sasseville, Anne-Marie Gélinas, Jean-Sébastien Milanese, Kathie Béland, Simon Drouin, Elie Haddad, Richard Marcotte

https://doi.org/10.3324/haematol.2022.280786

Small-molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy (631 Online Views)

Uta M. Demel, Matthias Wirth, Schayan Yousefian, Le Zhang, Konstandina Isaakidis, Judith Dönig, Marlitt Böger, Nikita Singh, Hazal Köse, Simon Haas, Stefan Müller, Markus Schick, Ulrich Keller

https://doi.org/10.3324/haematol.2022.280995

Sep 8, 2022

Articles

Targeting dual oncogenic machineries driven by TAL1 and PI3K-AKT pathways in T-cell acute lymphoblastic leukemia (483 Online Views)

Fang Qi Lim, Allison Si-Yu Chan, Rui Yokomori, Xiao Zi Huang, Madelaine Skolastika Theardy, Allen Eng Juh Yeoh, Shi Hao Tan, Takaomi Sanda

https://doi.org/10.3324/haematol.2022.280761

Sep 1, 2022

Articles

All-trans retinoic acid works synergistically with the γ-secretase inhibitor crenigacestat to augment BCMA on multiple myeloma and the efficacy of BCMA-CAR T cells (436 Online Views)

Estefanía García-Guerrero, Luis G. Rodríguez-Lobato, Belén Sierro-Martínez, Sophia Danhof, Stephan Bates, Silke Frenz, Larissa Härtle, Ralph Götz, Markus Sauer, Leo Rasche, K. Martin Kortüm, Jose A. Pérez-Simón, Hermann Einsele, Michael Hudecek, Sabrina R. Prommersberger

https://doi.org/10.3324/haematol.2022.281339

Aug 25, 2022

Editorials
Article

ASXL1 mutations accelerate bone marrow fibrosis via EGR1-TNFA axis mediated neoplastic fibrocyte generation in myeloproliferative neoplasms (599 Online Views)

Zhongxun Shi, Jinqin Liu, Yingying Zhao, Lin Yang, Yanan Cai, Peihong Zhang, Zefeng Xu, Tiejun Qin, Shiqiang Qu, Lijuan Pan, Junying Wu, Xin Yan, Zexing Li, Wenjun Zhang, Yiru Yan, Huijun Huang, Gang Huang, Bing Li, Xudong Wu, Zhijian Xiao

https://doi.org/10.3324/haematol.2021.280320

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Article

Characterization of therapy-related acute myeloid leukemia: increasing incidence and prognostic implications (805 Online Views)

Christer Nilsson, Fredrika Linde, Erik Hulegårdh, Hege Garelius, Vladimir Lazarevic, Petar Antunovic, Jörg Cammenga, Stefan Deneberg, Anna Eriksson, Martin Jädersten, Cecilia Kämpe Björkvall, Lars Möllgård, Lovisa Wennström, Emma Ölander, Martin Höglund, Gunnar Juliusson, Sören Lehmann

https://doi.org/10.3324/haematol.2022.281233

Editorials
Article

Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia (840 Online Views)

Binay K. Sahoo, Yuh-Charn Lin, Cheng-Fen Tu, Chien-Chin Lin, Wei-Ju Liao, Fu-An Li, Ling-Hui Li, Kurt Yun Mou, Steve R. Roffler, Shu-Ping Wang, Chi-Tai Yeh, Chi-Yuan Yao, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Ruey-Bing Yang

https://doi.org/10.3324/haematol.2022.281151

Articles

Serum vascular endothelial growth factor is associated with cardiovascular involvement and response to therapy in Erdheim-Chester disease (399 Online Views)

Anais Roeser, Marine Bravetti, Lida Dong, Levi-Dan Azoulay, Frederic Charlotte, Makoto Miyara, Pascale Ghillani-Dalbin, Jean-Francois Emile, Fadwa El Kouari, Hamza Ouni, Jean-Marc Lacorte, Isabelle Brocheriou, Zahir Amoura, Fleur Cohen-Aubart, Julien Haroche

https://doi.org/10.3324/haematol.2022.280755

BCL6 inhibition ameliorates resistance to ruxolitinib in CRLF2-rearranged acute lymphoblastic leukemia (609 Online Views)

Shinobu Tsuzuki, Takahiko Yasuda, Hiroaki Goto, Naoko Maeda, Koshi Akahane, Takeshi Inukai, Hideyuki Yamamoto, Sivasundaram Karnan, Akinobu Ota, Toshinori Hyodo, Hiroyuki Konishi, Yoshitaka Hosokawa, Hitoshi Kiyoi, Fumihiko Hayakawa

https://doi.org/10.3324/haematol.2022.280879

Aug 18, 2022

Articles

High transferrin saturation predicts inferior clinical outcomes in patients with myelodysplastic syndromes (500 Online Views)

Jennifer Teichman, Michelle Geddes, Nancy Zhu, Mary-Margaret Keating, Mitchell Sabloff, Grace Christou, Brian Leber, Dina Khalaf, Eve St-Hilaire, Nicholas Finn, April Shamy, Karen W.L. Yee, John M. Storring, Thomas J. Nevill, Robert Delage, Mohamed Elemary, Versha Banerji, Brett Houston, Lee Mozessohn, Lisa Chodirker, Liying Zhang, Mohammed Siddiqui, Anne Parmentier, Heather A. Leitch, Rena J. Buckstein

https://doi.org/10.3324/haematol.2022.280723

Selective inhibition of MCL1 overcomes venetoclax resistance in a murine model of myelodysplastic syndromes (763 Online Views)

Melissa A. Fischer, Yuanbin Song, Maria P. Arrate, Rana Gbyli, Matthew T. Villaume, Brianna N. Smith, Merrida A. Childress, Thomas P. Stricker, Stephanie Halene, Michael R. Savona

https://doi.org/10.3324/haematol.2022.280631

In vivo stabilization of a less toxic asparaginase variant leads to a durable antitumor response in acute leukemia (589 Online Views)

Maaike Van Trimpont, Amanda M. Schalk, Yanti De Visser, Hien Anh Nguyen, Lindy Reunes, Katrien Vandemeulebroecke, Evelien Peeters, Ying Su, Hyun Lee, Philip L. Lorenzi, Wai-Kin Chan, Veerle Mondelaers, Barbara De Moerloose, Tim Lammens, Steven Goossens, Pieter Van Vlierberghe, Arnon Lavie

https://doi.org/10.3324/haematol.2022.281390

Aug 11, 2022

Articles

Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300 (553 Online Views)

Franziska Hettler, Christina Schreck, Sandra Romero Marquez, Thomas Engleitner, Baiba Vilne, Theresa Landspersky, Heike Weidner, Renate Hausinger, Ritu Mishra, Rupert Oellinger, Martina Rauner, Ronald Naumann, Christian Peschel, Florian Bassermann, Roland Rad, Rouzanna Istvanffy, Robert A.J. Oostendorp

https://doi.org/10.3324/haematol.2022.280760

Molecular monitoring of T-cell kinetics and migration in severe neurotoxicity after real-world CD19-specific chimeric antigen receptor T cell therapy (1577 Online Views)

Susanna Carolina Berger, Boris Fehse, Nuray Akyüz, Maria Geffken, Christine Wolschke, Dietlinde Janson, Nico Gagelmann, Marlene Luther, Dominic Wichmann, Christian Frenzel, Guenther Thayssen, Anna Alegiani, Anita Badbaran, Silke Zeschke, Judith Dierlamm, Nicolaus Kröger, Francis A. Ayuk

https://doi.org/10.3324/haematol.2022.281110

Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against FLT3- mutant acute myeloid leukemia and KMT2A-rearranged acute lymphoblastic leukemia (1252 Online Views)

Lisa M. Niswander, Zachary T. Graff, Christopher D. Chien, John A. Chukinas, Christina A. Meadows, Lillie C. Leach, Joseph P. Loftus, M. Eric Kohler, Sarah K. Tasian, Terry J. Fry

https://doi.org/10.3324/haematol.2022.281456

Aug 4, 2022

Editorials
Letter to the Editor

Morbidity and mortality of sickle cell disease patients is unaffected by splenectomy: evidence from 3 decades follow-up in a high-income setting (332 Online Views)

Valeria Maria Pinto, Barbara Gianesin, Frédéric B. Piel, Filomena Longo, Paolo Rigano, Alessandra Quota, Vincenzo Spadola, Giovanna Graziadei, Filippo Mazzi, Maria Domenica Cappellini, Aurelio Maggio, Antonio Piga, Lucia De Franceschi, Gian Luca Forni

https://doi.org/10.3324/haematol.2022.280815

Articles

Translational readthrough at F8 nonsense variants in the factor VIII B domain contributes to residual expression and lowers inhibitor association (460 Online Views)

Maria Francesca Testa, Silvia Lombardi, Francesco Bernardi, Mattia Ferrarese, Donata Belvini, Paolo Radossi, Giancarlo Castaman, Mirko Pinotti, Alessio Branchini

https://doi.org/10.3324/haematol.2022.281279

Jul 28, 2022

Editorials
Article

Improving the anti-acute myeloid leukemia activity of CD123-specific Engager T cells by MyD88 and CD40 costimulation (1383 Online Views)

Abishek Vaidya, Erin Doherty, Xiya Wu, Sujuan Huang, Nikhil Hebbar, Unmesha Thanekar, Challice L. Bonifant, Cheng Cheng, Stephen Gottschalk, M. Paulina Velasquez

https://doi.org/10.3324/haematol.2021.279301

Jul 21, 2022

Editorials
Article

Hypercortisolemic Cushing's patients possess a distinct class of hematopoietic progenitor cells leading to erythrocytosis (633 Online Views)

Lilian Varricchio, Eliza B Geer, Fabrizio Martelli, Maria Mazzarini, Alister Funnell, James J Bieker, Thalia Papayannopoulou, Anna Rita Migliaccio

https://doi.org/10.3324/haematol.2021.280542

Editorials
Article

Time spent at home among older adults with acute myeloid leukemia receiving azacitidine- or venetoclax-based regimens (692 Online Views)

Christopher E. Jensen, Hilary M. Heiling, Konan E. Beke, Allison M. Deal, Ashley L. Bryant, Lorinda A. Coombs, Matthew C. Foster, Daniel R. Richardson

https://doi.org/10.3324/haematol.2022.280728

Jul 14, 2022

Editorials

Jun 30, 2022

Editorials
Article

Comparison of autologous and allogeneic hematopoietic cell transplantation strategies in patients with primary plasma cell leukemia, with dynamic prediction modelling (901 Online Views)

Sarah Lawless, Simona Iacobelli, Nina Simone Knelange, Patrice Chevallier, Didier Blaise, Noel Milpied, Roberto Foà, Jan J. Cornelissen, Bruno Lioure, Ruben Benjamin, Xavier Poiré, Monique C. Minnema, Matthew Collin, Stig Lenhoff, John A. Snowden, Stella Santarone, Keith M. O. Wilson, Fernanda Trigo, Peter Dreger, Lara H. Böhmer, Hein Putter, Laurent Garderet, Nicolaus Kröger, Ibrahim Yaukoub-Agha, Stefan Schönland, Curly Morris

https://doi.org/10.3324/haematol.2021.280568

Editorials

Articles

Comparison of autologous and allogeneic hematopoietic cell transplantation strategies in patients with primary plasma cell leukemia, with dynamic prediction modelling (901 Online Views)

Sarah Lawless, Simona Iacobelli, Nina Simone Knelange, Patrice Chevallier, Didier Blaise, Noel Milpied, Roberto Foà, Jan J. Cornelissen, Bruno Lioure, Ruben Benjamin, Xavier Poiré, Monique C. Minnema, Matthew Collin, Stig Lenhoff, John A. Snowden, Stella Santarone, Keith M. O. Wilson, Fernanda Trigo, Peter Dreger, Lara H. Böhmer, Hein Putter, Laurent Garderet, Nicolaus Kröger, Ibrahim Yaukoub-Agha, Stefan Schönland, Curly Morris

https://doi.org/10.3324/haematol.2021.280568

Jun 23, 2022

Editorials
Article

STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of BCL2 and BCLXL following glucocorticoid treatment (641 Online Views)

Jordy C.G. van der Zwet, Valentina Cordo’, Jessica G.C.A.M. Buijs-Gladdines, Rico Hagelaar, Willem K. Smits, Eric Vroegindeweij, Laura T.M. Graus, Vera Poort, Marloes Nulle, Rob Pieters, Jules P.P. Meijerink

https://doi.org/10.3324/haematol.2021.280405

Jun 16, 2022

Editorials
Article

Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning (1273 Online Views)

Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina M. Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang E. Berdel, Wolfgang Hiddemann, Frank Kroschinsky, Johannes Schetelig, Uwe Platzbecker, Carsten Müller-Tidow, Tim Sauer, Hubert Serve, Claudia Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan Krause, Mathias Hänel, Christoph Schliemann, Maher Hanoun, Christian Thiede, Martin Bornhäuser, Karsten Wendt, Jan Moritz Middeke

https://doi.org/10.3324/haematol.2021.280027

May 31, 2022

Editorials
Article

APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis (936 Online Views)

Simon Stritt, Paquita Nurden, Alan T. Nurden, Jean-François Schved, Jean-Claude Bordet, Maguelonne Roux, Marie-Christine Alessi, David-Alexandre Trégouët, Taija Mäkinen, Muriel Giansily-Blaizot

https://doi.org/10.3324/haematol.2022.280816

May 26, 2022

Editorials
Article

Durable discontinuation of systemic therapy in patients affected by chronic graft-versus-host disease (1344 Online Views)

George L. Chen, Lynn Onstad, Paul J. Martin, Paul Carpenter, Joseph Pidala, Sally Arai, Corey Cutler, Betty K. Hamilton, Stephanie J. Lee, Mukta Arora

https://doi.org/10.3324/haematol.2021.279814

Editorials
Article

Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease (607 Online Views)

Iryna A. Khasabova, Jacob Gable, Malcolm Johns, Sergey G. Khasabov, Alexander E. Kalyuzhny, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, Virginia S. Seybold, Donald A. Simone

https://doi.org/10.3324/haematol.2021.280460

May 19, 2022

Editorials
Article

Impact of PET-CT status on progression-free survival for relapsed follicular lymphoma patients undergoing autologous stem cell transplant (753 Online Views)

Toby A. Eyre, Sally F. Barrington, Jessica Okosun, Clementina Abamba, Rachel M. Pearce, Julia Lee, Ben Carpenter, Charles R. Crawley, Adrian J.C. Bloor, Maria Gilleece, Emma Nicholson, Nimish Shah, Kim Orchard, Ram Malladi, William M. Townsend

https://doi.org/10.3324/haematol.2021.280287

May 12, 2022

Editorials
Letter to the Editor

Integrating biological HLA-DPB1 mismatch models to predict survival after unrelated hematopoietic cell transplantation (741 Online Views)

Annalisa Ruggeri, Liesbeth C. de Wreede, Carlheinz R. Müller, Pietro Crivello, Edouard F. Bonneville, Effie W. Petersdorf, Gerard Socié, Valérie Dubois, Riitta Niittyvuopio, Juha Peräsaari, Ibrahim Yakoub-Agha, Jan J. Cornelissen, Lotte Wieten, Tobias Gedde-Dahl, Edouard Forcade, Charles R. Crawley, Steven G.E. Marsh, Virginie Gandemer, Eleni Tholouli, Claude-Eric Bulabois, Anne Huynh, Goda Choi, Eric Deconinck, Maija Itäla-Remes, Stig Lenhoff, Mats Bengtsson, Jan-Erik Johansson, Gwendolyn van Gorkom, Jorinde D. Hoogenboom, Luca Vago, Vanderson Rocha, Chiara Bonini, Christian Chabannon, Katharina Fleischhauer

https://doi.org/10.3324/haematol.2021.280055

Apr 28, 2022

Editorials
Article

Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B-cell lymphomas (992 Online Views)

Cristina Lopez, Nikolai Schleussner, Stephan H. Bernhart, Kortine Kleinheinz, Stephanie Sungalee, Henrike L. Sczakiel, Helene Kretzmer, Umut H. Toprak, Selina Glaser, Rabea Wagener, Ole Ammerpohl, Susanne Bens, Maciej Giefing, Juan C. Gonzalez Sanchez, Gordana Apic, Daniel Hubschmann, Martin Janz, Markus Kreuz, Anja Mottok, Judith M. Muller, Julian Seufert, Steve Hoffmann, Jan O. Korbel, Robert B. Russell, Roland Schule, Lorenz Trumper, Wolfram Klapper, Bernhard Radlwimmer, Peter Lichter, Ralf Kuppers, Matthias Schlesner, Stephan Mathas, Reiner Siebert

https://doi.org/10.3324/haematol.2021.280005

Editorials

Editorials
Article

Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement (1296 Online Views)

Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. de Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell

https://doi.org/10.3324/haematol.2021.280557

Jan 13, 2022

Articles

Oncogenic TYK2P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade (1160 Online Views)

Katharina Woess, Sabine Macho-Maschler, Dorette S. van Ingen Schenau, Miriam Butler, Caroline Lassnig, Daniel Valcanover, Andrea Poelzl, Katrin Meissl, Barbara Maurer, Tania Brandstoetter, Claus Vogl, Anna Koren, Stefan Kubicek, Anna Orlova, Richard Moriggl, Birgit Strobl, Veronika Sexl, Frank N. van Leeuwen, Roland P. Kuiper, Mathias Mueller

https://doi.org/10.3324/haematol.2021.279848

Aug 19, 2021

Errata Corrige

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma (2564 Online Views)

Johannes Duell, Kami J. Maddocks, Eva González-Barca, Wojciech Jurczak, Anna Marina Liberati, Sven de Vos, Zsolt Nagy, Aleš Obr, Gianluca Gaidano, Pau Abrisqueta, Nagesh Kalakonda, Marc André, Martin Dreyling, Tobias Menne, Olivier Tournilhac, Marinela Augustin, Andreas Rosenwald, Maren Dirnberger-Hertweck, Johannes Weirather, Sumeet Ambarkhane, Gilles Salles

https://doi.org/10.3324/haematol.2021.279802

May 10, 2018

Articles

GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells (1011 Online Views)

Beibei Zhang, Pilar Ayuda Durán, Laure Piechaczyk, Yngvar Fløisand, Mireia Mayoral Safont Safont, Ida Tveit Karlsen, Zina Fandalyuk, Dagim Tadele, Pepijn van Mierlo, Alexander D. Rowe, Joseph M. Robertson, Bjørn Tore Gjertsen, Emmet McCormack, Jorrit M. Enserink, Bjørn Tore Gjertsen Group, Emmet McCormack Group

https://doi.org/10.3324/haematol.2018.189399