Early view

Oct 3, 2024

Articles

Pirtobrutinib monotherapy in Bruton tyrosine kinase inhibitor-intolerant patients with B-cell malignancies: results of the phase I/II BRUIN trial (196 Online Views)

Nirav N. Shah, Michael Wang, Lindsey E. Roeker, Krish Patel, Jennifer A. Woyach, William G. Wierda, Chaitra S. Ujjani, Toby A. Eyre, Pier Luigi Zinzani, Alvaro J. Alencar, Paolo Ghia, Nicole Lamanna, Marc S. Hoffmann, Manish R. Patel, Ian Flinn, James N. Gerson, Shuo Ma, Catherine C. Coombs, Chan Y. Cheah, Ewa Lech-Maranda, Bita Fakhri, Won Seog Kim, Minal A. Barve, Jonathon B. Cohen, Wojciech Jurczak, Talha Munir, Meghan C. Thompson, Donald E. Tsai, Katherine Bao, Nicholas A. Cangemi, Jennifer F. Kherani, Richard A. Walgren, Hongmei Han, Amy S. Ruppert, Jennifer R. Brown

https://doi.org/10.3324/haematol.2024.285754

Outcome of adult acute myeloid leukemia patients with extramedullary disease and treatment with venetoclax/hypomethylating agents (125 Online Views)

Sabine Kayser, Khaled Sanber, Giovanni Marconi, Agnese Mattei, Marlise R. Luskin, Amar Kelkar, Marco Cerrano, Daniel Tuyet Kristensen, Anne Stidsholt Roug, Chiara Sartor, Fabio Giglio, Marta Riva, Lorenzo Rizzo, Francesco Saraceni, Selene Guerzoni, Federica Lessi, Erika Borlenghi, Mark J. Levis, Richard F. Schlenk, Tania Jain, Cristina Papayannidis

https://doi.org/10.3324/haematol.2024.285985

Letters to the Editor

Epigenetic age acceleration in hematopoietic stem cell transplantation (105 Online Views)

Margherita Ursi, Katarzyna Malgorzata Kwiatkowska, Chiara Pirazzini, Gianluca Storci, Daria Messelodi, Salvatore Nicola Bertuccio, Serena De Matteis, Francesco Iannotta, Enrica Tomassini, Marcello Roberto, Maria Naddeo, Noemi Laprovitera, Irene Salamon, Barbara Sinigaglia, Elisa Dan, Francesco De Felice, Francesco Barbato, Enrico Maffini, Sadia Falcioni, Mario Arpinati, Manuela Ferracin, Massimiliano Bonafè, Paolo Garagnani, Francesca Bonifazi

https://doi.org/10.3324/haematol.2024.285291

Temporal changes in erythroid progenitors in critically ill patients: a prospective cohort study (56 Online Views)

Caroline Scott, Isabella Dale-Harris, Andrew E. Armitage, Alexandra E Preston, Simon J. Stanworth, Timothy James, Stuart R. McKechnie, Peter A. Robbins, Hal Drakesmith, Noemi B.A. Roy, Akshay Shah

https://doi.org/10.3324/haematol.2024.285530

Evaluating serum free light chain ratio as a biomarker in multiple myeloma (185 Online Views)

Theresia Akhlaghi, Kylee Maclachlan, Neha Korde, Sham Mailankody, Alexander Lesokhin, Hani Hassoun, Sydney X. Lu, Dhwani Patel, Urvi Shah, Carlyn Tan, Andriy Derkach, Oscar Lahoud, Heather J. Landau, Gunjan L. Shah, Michael Scordo, David J. Chung, Sergio A. Giralt, Saad Z. Usmani, Ola Landgren, Malin Hultcrantz

https://doi.org/10.3324/haematol.2024.285531

Single-cell analysis of the T-cell receptor repertoire in untreated myeloma patients suggests potential myeloma-reactive CD8+ T-cells are shared between blood and marrow (63 Online Views)

James Favaloro, Christian E. Bryant, Edward Abadir, Samuel Gardiner, Shihong Yang, Tracy King, Najah Nassif, Bronwyn A. O’Brien, Lisa M. Sedger, Richard Boyle, Douglas E. Joshua, P. Joy Ho

https://doi.org/10.3324/haematol.2024.285952

Perspective Articles

Sep 26, 2024

Articles

Letters to the Editor

Safety and efficacy of human amniotic epithelial stem cell eye drops in ocular chronic graft-versus-host disease (62 Online Views)

Xianjing Cheng, Wei Fan, Ruihao Huang, Yuancheng Zhao, Yonghong Tang, Shiqin Huang, Guanghui Zhang, Xi Zhang, Rongdi Yuan, Xiaoqi Wang

https://doi.org/10.3324/haematol.2023.284571

BET inhibitors down-regulate the expression of the essential lncRNA SMILO in multiple myeloma through regulation of the transcription factor FLI1 (102 Online Views)

Nahia Gómez-Echarte, Edurne San José-Enériz, Arantxa Carrasco-León, Naroa Barrena, Estibaliz Miranda, Leire Garate, Beatriz García-Torre, Sandra Alonso-Moreno, Naroa Gimenez-Camino, Estibaliz Urizar-Compains, Danel Olaverri-Mendizabal, Paula Aguirre-Ruiz, Beñat Ariceta, Luis-Esteban Tamariz-Amador, Paula Rodriguez-Otero, Francisco J. Planes, Laura Belver, José Ignacio Martín-Subero, Felipe Prosper, Xabier Agirre

https://doi.org/10.3324/haematol.2024.285966

Sep 19, 2024

Letters to the Editor

Susceptibility to BK polyomavirus-associated hemorrhagic cystitis in children undergoing allogeneic transplant (82 Online Views)

Sheyar Abdullah, Anthony Sabulski, Zahra Hudda, Assem Ziady, Nathan Luebbering, Lucy Giordullo, Elizabeth Odegard, Jason T. Blackard, Steve Kleiboeker, Michelle Altrich, Sonata Jodele, Alix E. Seif, Stella M. Davies, Benjamin L. Laskin

https://doi.org/10.3324/haematol.2024.286163

Comments

Sep 12, 2024

Editorials
Letter to the Editor

Rituximab maintenance after bendamustine-based treatment for follicular lymphoma and mantle cell lymphoma may exert a negative influence on SARS-CoV-2 infection outcomes (498 Online Views)

Ángel Serna, Víctor Navarro, Gloria Iacoboni, Laia López, Juan-Manuel Sancho, Eva González-Barca, Alberto López-García, Raúl Córdoba, Adolfo Sáez, Ana Jiménez Ubieto, Ainara Ferrero, Tomás García, Ángela Sánchez, Cristina García, Marc Bosch, Alba Cabirta, Moraima Jiménez, Ana Marín-Niebla, Francesc Bosch, Pau Abrisqueta

https://doi.org/10.3324/haematol.2024.285219

Articles

Immune reconstitution dynamics after unrelated allogeneic transplantation with post-transplant cyclophosphamide compared to classical immunosuppression with anti-thymocyte globulin: a prospective cohort study (260 Online Views)

Mariana Nassif Kerbauy, Fernanda Agostini Rocha, Leonardo Javier Arcuri, Priscila Silva Cunegundes, Lucila Nassif Kerbauy, Clarisse Martins Machado, Andreza Alice Feitosa Ribeiro, Pinaki P. Banerjee, Luciana Cavalheiro Marti, Nelson Hamerschlak

https://doi.org/10.3324/haematol.2024.285921

Letters to the Editor

Intra-marrow delivery of human interleukin-6-loaded biodegradable microspheres promotes growth of patient-derived multiple myeloma cells in mice (162 Online Views)

Manpreet Bariana, Weiwei Wang, Zhuozhuo Yin, Jingyu Sun, Shabnam Samimi, Shaina A. Anuncio, Elena Cassella, Nuo Xu, Wei Hu, Ariel Aptekmann, David S. Siegel, Kar F. Chow, Hongjun Wang, Johannes L. Zakrzewski

https://doi.org/10.3324/haematol.2024.285980

A phase I study of MAGE-A1-targeted T1367 T-cell receptor-based cell therapy in patients with advanced multiple myeloma (315 Online Views)

Josefine Krüger, Matthias Obenaus, Igor Wolfgang Blau, Dana Hoser, Martin Vaegler, Hana Rauschenbach, Ioannis Anagnostopoulos, Korinna Jöhrens, Vivian Scheuplein, Elisa Kieback, Judith Böhme, Ann-Christin von Brünneck, Jan Krönke, Antonia Busse, Gerald Willimsky, Thomas Blankenstein, Antonio Pezzutto, Ulrich Keller, Axel Nogai

https://doi.org/10.3324/haematol.2024.286124

Sep 5, 2024

Editorials
Article

Outcome of 421 adult patients with Philadelphia-negative acute lymphoblastic leukemia treated under an intensive program inspired by the GIMEMA LAL1913 clinical trial: a Campus ALL study (526 Online Views)

Davide Lazzarotto, Marco Cerrano, Cristina Papayannidis, Sabina Chiaretti, Federico Mosna, Nicola Fracchiolla, Patrizia Zappasodi, Silvia Imbergamo, Maria Ilaria Del Principe, Monia Lunghi, Federico Lussana, Matteo Piccini, Monica Fumagalli, Michelina Dargenio, Prassede Salutari, Fabio Forghieri, Teresa Giulia Da Molin, Massimiliano Bonifacio, Matteo Olivi, Fabio Giglio, Silvia Trappolini, Matteo Leoncin, Antonino Mule, Mario Delia, Crescenza Pasciolla, Francesco Grimaldi, Benedetta Cambo, Lidia Santoro, Fabio Guolo, Paola Minetto, Marzia Defina, Patrizia Chiusolo, Matteo Fanin, Endri Mauro, Lara Aprile, Carla Mazzone, Fabio Trastulli, Maria Ciccone, Marco De Gobbi, Alessandro Cignetti, Eleonora De Bellis, Valentina Mancini, Alfonso Piciocchi, Marco Vignetti, Giovanni Marsili, Irene Della Starza, Renato Fanin, Mario Luppi, Felicetto Ferrara, Giovanni Pizzolo, Renato Bassan, Robin Foa, Anna Candoni

https://doi.org/10.3324/haematol.2024.285638

Review Articles

Articles

Safety and efficacy of acalabrutinib plus bendamustine and rituximab in patients with treatment-naive or relapsed / refractory mantle cell lymphoma: phase Ib trial (373 Online Views)

Tycel Phillips, Michael Wang, Tadeusz Robak, David Gallinson, Don Stevens, Krish Patel, Safaa Ramadan, Chuan-Chuan Wun, Wojciech Jurczak, Stephen D. Smith

https://doi.org/10.3324/haematol.2023.284896

Loncastuximab tesirine in Chinese patients with relapsed or refractory diffuse large B-cell lymphoma: a multicenter, open-label, single-arm, phase II trial (325 Online Views)

Ningjing Lin, Xiuhua Sun, Hui Zhou, Liqun Zou, Keshu Zhou, Lihong Liu, Haiyan Yang, Kai Hu, Qingqing Cai, Yao Liu, Jie Jin, Liling Zhang, Wenyu Li, Ye Guo, Wei Yang, Feng Luo, Zhenguang Wang, Rong Zhu, Lei Yang, Dan Song, Yuqin Song, Jun Zhu

https://doi.org/10.3324/haematol.2024.284973

BCAT1 is a NOTCH1 target and sustains the oncogenic function of NOTCH1 (278 Online Views)

Valeria Tosello, Ludovica Di Martino, Adonia E. Papathanassiu, Silvia Dalla Santa, Marco Pizzi, Lara Mussolin, Jingjing Liu, Pieter van Vlierberghe, Erich Piovan

https://doi.org/10.3324/haematol.2024.285552

Rituximab and lenalidomide for the treatment of relapsed or refractory indolent non-Hodgkin lymphoma: real-life experience (372 Online Views)

Giulio Cassanello, Esther Drill, Alfredo Rivas-Delgado, Michelle Okwali, Irem Isgor, Philip C. Caron, Zachary Epstein-Peterson, Paola Ghione, Paul Hamlin, Jennifer Lue, Steven M. Horwitz, Andrew M. Intlekofer, William Johnson, Anita Kumar, Alison Moskowitz, Ariela Noy, Colette Owens, Lia M. Palomba, Pallawi Torka, Pallavi Galera, Andrew D. Zelenetz, Gilles Salles, Lorenzo Falchi

https://doi.org/10.3324/haematol.2024.285600

Letters to the Editor

Outcomes of patients with primary central nervous system lymphoma following CD19-targeted chimeric antigen receptor T-cell therapy (730 Online Views)

Santiago Mercadal, Kwang Woo Ahn, Mariam Allbee-Johnson, Siddhartha Ganguly, Praveen Ramakrishnan Geethakumari, Sanghee Hong, Adriana Malone, Hemant Murthy, Attaphol Pawarode, Alejandro R. Sica, Melhem Solh, Celalettin Ustun, Mazyar Shadman, Craig S. Sauter, Mehdi Hamadani, Alex F. Herrera, Catherine J. Lee

https://doi.org/10.3324/haematol.2024.285613

Prognostic stratification in venetoclax-based acute myeloid leukemia treatments: the molecular prognostic risk signature tested in a real-world setting (250 Online Views)

Gaia Ciolli, Matteo Piccini, Francesco Mannelli, Giacomo Gianfaldoni, Barbara Scappini, Laura Fasano, Francesca Crupi, Elisa Quinti, Andrea Pasquini, Jessica Caroprese, Giada Rotunno, Fabiana Pancani, Leonardo Signori, Chiara Maccari, Fiorenza I. Vanderwert, Paola Guglielmelli, Alessandro M. Vannucchi

https://doi.org/10.3324/haematol.2024.285934

Adverse prognostic impact of KIT exon 17 mutations despite negative flow cytometric measurable residual disease in pediatric acute myeloid leukemia with RUNX1::RUNX1T1 (378 Online Views)

Shota Kato, Shin-Ichi Tsujimoto, Jun Matsubayashi, Shotaro Iwamoto, Hidefumi Hiramatsu, Yusuke Okuno, Tatsuya Kamitori, Kentaro Ohki, Takao Deguchi, Nobutaka Kiyokawa, Motohiro Kato, Junko Takita, Shiro Tanaka, Souichi Adachi, Daisuke Tomizawa, Norio Shiba

https://doi.org/10.3324/haematol.2024.286243

Aug 29, 2024

Editorial
Article

Combinatorial strategies targeting NEAT1 and AURKA as new potential therapeutic options for multiple myeloma (613 Online Views)

Noemi Puccio, Gloria Manzotti, Elisabetta Mereu, Federica Torricelli, Domenica Ronchetti, Michela Cumerlato, Ilaria Craparotta, Laura Di Rito, Marco Bolis, Valentina Traini, Veronica Manicardi, Valentina Fragliasso, Yvan Torrente, Nicola Amodio, Niccolò Bolli, Elisa Taiana, Alessia Ciarrocchi, Roberto Piva, Antonino Neri

https://doi.org/10.3324/haematol.2024.285470

Editorial
Article

Distinctive genomic features of human T-lymphotropic virus type 1-related adult T-cell leukemia-lymphoma in Western populations (557 Online Views)

Caroline S. Myers, Eli Williams, Carlos Barrionuevo Cornejo, Georgios Pongas, Ngoc L. Toomey, Jose A. Sanches, Maxime Battistella, Samuel Mo, Melissa Pulitzer, Cristopher A. Moskaluk, Govind Bhagat, Kenneth Ofori, Jonathan J. Davick, Octavio Servitje, Denis Miyashiro, Fina Climent, Kimberley Ringbloom, Daniela Duenas, Calvin Law, Sandro Casavilca Zambrano, Luis Malpica, Brady E. Beltran, Denisse Castro, Luciana Barreto, Carlos Brites, Jennifer R. Chapman, Jaehyuk Choi, Alejandro A. Gru, Juan C. Ramos

https://doi.org/10.3324/haematol.2024.285233

Articles

Utilization of allogeneic hematopoietic stem cell transplantation among patients with newly diagnosed acute myeloid leukemia in California: a population-based linked dataset study (214 Online Views)

Christa L. Meyer, Theresa H.M. Keegan, Ann Brunson, Jeffery J. Auletta, Lindsay M. Morton, Ted Wun, Sara J. Schonfeld, Bryan Valcarcel, Renata Abrahão, Rafeek A. Yusuf, Lori Muffly

https://doi.org/10.3324/haematol.2024.285648

T-cell receptor architecture and clonal tiding provide insight into the transformation trajectory of peripheral T-cell lymphomas (405 Online Views)

Edith Willscher, Christoph Schultheiß, Lisa Paschold, Franziska Lea Schümann, Paul Schmidt-Barbo, Benjamin Thiele, Marcus Bauer, Claudia Wickenhauser, Thomas Weber, Mascha Binder

https://doi.org/10.3324/haematol.2024.285395

Letters to the Editor

Characteristics and outcomes associated with CD2 and CD25 expression on bone marrow mast cells in patients with systemic mastocytosis (268 Online Views)

Julien Rossignol, Sophie Georgin-Lavialle, Danielle Canioni, Omer Beganovic, Chantal Brouzes, Olivier Fain, Maël Heiblig, Clément Gourguechon, Philippe Guilpain, Cristina Bulai-Livideanu, Stéphane Barete, Julie Agopian, Fabienne Brenet, Patrice Dubreuil, Richard Lemal, Olivier Tournilhac, Louis Terriou, David Launay, Laurence Bouillet, Catharina Chatain, Ghandi Damaj, Thomas Ballul, Celine Greco, Laura Polivka, Laurent Frenzel, Cécile Meni, Hassiba Bouktit, Dina Benabou, Clotilde Devin, Caroline Gaudy-Marqueste, Marie Gousseff, Edwige Le Mouel, Antoine Neel, Dana Ranta, Roland Jaussaud, Thierry Jo Molina, Julie Bruneau, Rose-Marie Javier, Fabien Pelletier, Florence Castelain, Frederique Retornaz, Quentin Cabrera, Patricia Zunic, Marie Pierre Gourin, Ewa Wierzbicka-Hainaut, Jean François Viallard, Christian Lavigne, Cyrille Hoarau, Isabelle Durieu, Sophie Dimicoli-Salazar, Jose Miguel Torregrosa-Diaz, Audrey Duval, Nicolas Garcelon, Jeremie Lespinasse, Angèle Soria, Yannick Chantran, Michel Arock, Christine Bodemer, Olivier Lortholary, Vahid Asnafi, Olivier Hermine, Ludovic Lhermitte

https://doi.org/10.3324/haematol.2024.285740

Aug 22, 2024

Editorial
Article

Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia (714 Online Views)

Mohd Minhajuddin, Amanda Winters, Haobin Ye, Shanshan Pei, Brett Stevens, Austin Gillen, Krysta Engel, Stephanie Gipson, Monica Ransom, Maria Amaya, Anagha Inguva, Maura Gasparetto, Mark J. Althoff, Regan Miller, Ian Shelton, Hunter Tolison, Anna Krug, Rachel Culp-Hill, Angelo D’Alessandro, Daniel W Sherbenou, Daniel A. Pollyea, Clayton Smith, Craig T Jordan

https://doi.org/10.3324/haematol.2023.284716

Letters to the Editor

Hodgkin/Reed-Sternberg cells induce GPNMB expression and release from macrophages to suppress T-cell responses to the Epstein-Barr virus-encoded LMP2A protein (243 Online Views)

Navta Masand, Tracey A. Perry, Matthew Pugh, Eanna Fennell, Aoife Hennessy, Wenbin Wei, Katerina Bouchalova, David Burns, Pamela Kearns, Graham Taylor, Katerina Vrzalikova, Paul G. Murray

https://doi.org/10.3324/haematol.2024.285319

Infection by Helicobacter pylori cytotoxin-A-associated antigen-positive strains is associated with iron deficiency anemia in a longitudinal birth cohort in Brazil (184 Online Views)

Dulciene M. M. Queiroz, Lucia L. C. Braga, Gifone A. Rocha, Sérgio A. Batista, Andreia M. C. Rocha, Mayuko Saito, William Checkley, Robert H. Gilman, Jean E. Crabtree

https://doi.org/10.3324/haematol.2024.285446

Comparing the clinical trial efficacy versus real-world effectiveness of treatments for multiple myeloma: a population-based study (417 Online Views)

Alissa Visram, Kelvin Kar-Wing Chan, Hsien Seow, Gregory Pond, Anastasia Gayowsky, Ghulam Rehman Mohyuddin, Arleigh McCurdy, Irwindeep Sandhu, Christopher Venner, Guido Lancman, Amaris Balitsky, Tom Kouroukis, Robert Bruins, Shaji Kumar, Rafael Fonseca, Hira Mian

https://doi.org/10.3324/haematol.2024.285768

Aug 15, 2024

Articles

Outcome of 421 adult patients with Philadelphia-negative acute lymphoblastic leukemia treated under an intensive program inspired by the GIMEMA LAL1913 clinical trial: a Campus ALL study (526 Online Views)

Davide Lazzarotto, Marco Cerrano, Cristina Papayannidis, Sabina Chiaretti, Federico Mosna, Nicola Fracchiolla, Patrizia Zappasodi, Silvia Imbergamo, Maria Ilaria Del Principe, Monia Lunghi, Federico Lussana, Matteo Piccini, Monica Fumagalli, Michelina Dargenio, Prassede Salutari, Fabio Forghieri, Teresa Giulia Da Molin, Massimiliano Bonifacio, Matteo Olivi, Fabio Giglio, Silvia Trappolini, Matteo Leoncin, Antonino Mule, Mario Delia, Crescenza Pasciolla, Francesco Grimaldi, Benedetta Cambo, Lidia Santoro, Fabio Guolo, Paola Minetto, Marzia Defina, Patrizia Chiusolo, Matteo Fanin, Endri Mauro, Lara Aprile, Carla Mazzone, Fabio Trastulli, Maria Ciccone, Marco De Gobbi, Alessandro Cignetti, Eleonora De Bellis, Valentina Mancini, Alfonso Piciocchi, Marco Vignetti, Giovanni Marsili, Irene Della Starza, Renato Fanin, Mario Luppi, Felicetto Ferrara, Giovanni Pizzolo, Renato Bassan, Robin Foa, Anna Candoni

https://doi.org/10.3324/haematol.2024.285638

Letters to the Editor

A multi-center, phase Ib study of subcutaneous administration of isatuximab in combination with pomalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma (763 Online Views)

Hang Quach, Gurdeep Parmar, Enrique M. Ocio, H. Miles Prince, Albert Oriol, Helen Crowther, Nobuhiro Tsukada, Pierre Bories, Sumit Madan, Nitya Nathwani, Kazutaka Sunami, Dorothee Semiond, Disa Yu, Paul Cordero, Sandrine Macé, Florence Suzan, Philippe Moreau

https://doi.org/10.3324/haematol.2023.284730

Cd39 and P2rx7-Wnt signaling enhance blast pathogenicity in an experimental model of acute myeloid leukemia (283 Online Views)

Lili Feng, Haohai Zhang, Changchuin Mao, Paola de Andrade Mello, Dina Stroopinsky, Eva Csizmadia, Jialin Zhou, David Avigan, Jinming Yu, Wenda Gao, Simon C. Robson

https://doi.org/10.3324/haematol.2024.285547

A novel prognostic nomogram based on imaging and molecular parameters for newly diagnosed extranodal natural killer/T-cell lymphoma patients (287 Online Views)

Dezhi Huang, Fu Li, Shijia Lin, Jing Xia, Bangdong Liu, Xinlei Li, Naya Ma, Yishuo Duan, Yunjing Zeng, Sha Zhou, Shuhan Tang, Wenqiu Huang, Lingyi Rao, Li Gao, Qiong Li, Xi Zhang, Jun Rao

https://doi.org/10.3324/haematol.2024.285362

Comments

Aug 8, 2024

Editorials
Article

Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma (864 Online Views)

Nicholas Davies, Tegan Francis, Ceri Oldreive, Maria Azam, Jordan Wilson, Philip J. Byrd, Megan Burley, Archana Sharma-Oates, Peter Keane, Sael Alatawi, Martin R. Higgs, Zbigniew Rudzki, Maha Ibrahim, Tracey Perry, Angelo Agathanggelou, Anne-Marie Hewitt, Edward Smith, Constanze Bonifer, Mark O’Connor, Josep V. Forment, Paul G. Murray, Eanna Fennell, Gemma Kelly, Catherine Chang, Grant S. Stewart, Tatjana Stankovic, Marwan Kwok, Alexander Malcolm Taylor

https://doi.org/10.3324/haematol.2023.284404

Articles

LP-118 is a novel B-cell lymphoma 2 / extra-large inhibitor that demonstrates efficacy in models of venetoclax-resistant chronic lymphocytic leukemia (543 Online Views)

Janani Ravikrishnan, Daisy Y. Diaz-Rohena, Elizabeth Muhowski, Xiaokui Mo, Tzung-Huei Lai, Shrilekha Misra, Charmelle D. Williams, John Sanchez, Andrew Mitchell, Suresh Satpati, Elizabeth Perry, Tierney Kaufman, Chaomei Liu, Arletta Lozanski, Gerard Lozanski, KerryA Rogers, Adam S. Kittai, Seema A. Bhat, Mary C. Collins, Matthew S. Davids, Nitin Jain, William G. Wierda, Rosa Lapalombella, John C. Byrd, Fenlai Tan, Yi Chen, Yu Chen, Yue Shen, Stephen P. Anthony, Jennifer A. Woyach, Deepa Sampath

https://doi.org/10.3324/haematol.2023.284353

Distinctive genomic features of human T-lymphotropic virus type 1-related adult T-cell leukemia-lymphoma in Western populations (557 Online Views)

Caroline S. Myers, Eli Williams, Carlos Barrionuevo Cornejo, Georgios Pongas, Ngoc L. Toomey, Jose A. Sanches, Maxime Battistella, Samuel Mo, Melissa Pulitzer, Cristopher A. Moskaluk, Govind Bhagat, Kenneth Ofori, Jonathan J. Davick, Octavio Servitje, Denis Miyashiro, Fina Climent, Kimberley Ringbloom, Daniela Duenas, Calvin Law, Sandro Casavilca Zambrano, Luis Malpica, Brady E. Beltran, Denisse Castro, Luciana Barreto, Carlos Brites, Jennifer R. Chapman, Jaehyuk Choi, Alejandro A. Gru, Juan C. Ramos

https://doi.org/10.3324/haematol.2024.285233

Immunoglobulin prophylaxis prevents hospital admissions for fever in pediatric acute lymphoblastic leukemia: results of a multicenter randomized trial (580 Online Views)

Kirsten A. Thus, Hester A. de Groot-Kruseman, Pauline Winkler-Seinstra, Marta Fiocco, Heidi Segers, Cor van den Bos, Inge M. van der Sluis, Wim J.E. Tissing, Margreet A. Veening, Christian Michel Zwaan, Cornelis M. van Tilburg, Rob Pieters, Marc Bierings

https://doi.org/10.3324/haematol.2024.285428

Hematopoietic cell transplantation for older acute myeloid leukemia patients in first complete remission: results of a randomized phase III study (974 Online Views)

Dietger Niederwieser, Dirk Hasenclever, Wolfgang E. Berdel, Bart J. Biemond, Haifa Al-Ali, Yves Chalandon, Michel van Gelder, Christian Junghanß, Gösta Gahrton, Mathias Hänel, Rüdiger Hehlmann, Thomas Heinicke, Andreas Hochhaus, Simona Iacobelli, Rien van Marwijk Kooy, Nicolaus Kröger, Jeroen Janssen, Madlen Jentzsch, Frank Breywisch, Mohamad Mohty, Stavroula Masouridi-Levrat, Gert Ossenkoppele, Jacob Passweg, Wolfram Pönisch, Johannes Schetelig, Christoph Schliemann, Sebastian Schwind, Matthias Stelljes, Leo F. Verdonck, Vladan Vucinic, Bob Löwenberg, Jan Cornelissen

https://doi.org/10.3324/haematol.2024.285879

Letters to the Editor

A phase II study of post-remission therapy with pembrolizumab in older patients with acute myeloid leukemia (268 Online Views)

Kevin Quann, Konstantinos Lontos, Alison Sehgal, Anastasios Raptis, Annie Im, Robert L. Redner, Kathleen A. Dorritie, Mounzer Agha, Jing-Zhou Hou, Rafic Farah, James Rossetti, Daniel P. Normolle, Theresa L. Whiteside, Yen-Michael Sheng Hsu, Michael Boyiadzis

https://doi.org/10.3324/haematol.2024.285313

Contribution of copy number to improve risk stratification of adult T-cell acute lymphoblastic leukemia patients enrolled in measurable residual disease-oriented trials (232 Online Views)

Celia Gonzalez-Gil, Mireia Morgades, Thaysa Lopes, Francisco Fuster-Tormo, Pau Montesinos, Pere Barba, Marina Diaz-Beya, Lourdes Hermosin, Clara Maluquer, Jose Gonzalez-Campos, Teresa Bernal, Marta Sitges Arriaga, Lurdes Zamora, Marta Pratcorona, Rodrigo Martino, Maria Jose Larrayoz, Teresa Artola, Anna Torrent, Ferran Vall-llovera, Mar Tormo, Cristina Gil, Andres Novo, Pilar Martinez-Sanchez, Jordi Ribera, Maria-Paz Queipo, Teresa Gonzalez-Martinez, Monica Cabrero, Antonia Cladera, Jose Cervera, Alberto Orfao, Josep Maria Ribera, Eulalia Genesca

https://doi.org/10.3324/haematol.2024.285416

Repurposing CD19-directed immunotherapies for pediatric t(8;21) acute myeloid leukemia (539 Online Views)

Farnaz Barneh, Joost B. Koedijk, Noa E. Wijnen, Tom Meulendijks, Minoo Ashtiani, Ester Dunnebach, Noël Dautzenberg, Annelisa M. Cornel, Anja Krippner-Heidenreich, Kim Klein, Michel C. Zwaan, Jürgen Kuball, Stefan Nierkens, Jacqueline Cloos, Gertjan J.L. Kaspers, Olaf Heidenreich

https://doi.org/10.3324/haematol.2024.285707

Case Reports

Aug 1, 2024

Letters to the Editor

Superior survival with allogeneic hematopoietic stem cell transplantation versus chemotherapy for high-risk adult acute lymphoblastic leukemia in a PDT-ALL-2016 pediatric-inspired cohort (312 Online Views)

Junjie Chen, Zihong Cai, Zicong Huang, Jieping Lin, Zhixiang Wang, Jiawang Ou, Xiuli Xu, Bingqing Tang, Chenhao Ding, Jia Li, Ren Lin, Ting Zhang, Li Xuan, Qifa Liu, Hongsheng Zhou

https://doi.org/10.3324/haematol.2024.285590

Comments

Case Reports

Ponatinib alone or with chemo-immunotherapy in heavily pre-treated Philadelphia-like acute lymphoblastic leukemia: a CAMPUS ALL real-life study (468 Online Views)

Francesca Kaiser, Monia Lunghi, Deborah Cardinali, Vittorio Bellomarino, Marco Beldinanzi, Irene Della Starza, Francesco Malfona, Claudia M. Basilico, Marzia Defina, Sara Mastaglio, Fabio Giglio, Davide Lazzarotto, Prassede Salutari, Matteo Piccini, Valeria Cardinali, Antonio Pierini, Nicola S. Fracchiolla, Federica Di Biase, Mario Annunziata, Mariangela Di Trani, Robin Foa, Sabina Chiaretti

https://doi.org/10.3324/haematol.2024.285258

Expanding the genetic landscape of congenital neutropenia: CXCR2 mutations in three families revealed through whole exome sequencing (346 Online Views)

Maksim Klimiankou, Ivan Tesakov, Grigorios Tsaknakis, Erasmia Boutakoglou, Irene Mavroudi, Malte Ritter, Marc Sturm, Julia Skokowa, Helen A. Papadaki

https://doi.org/10.3324/haematol.2024.285569

Spotlight Review

Jul 25, 2024

Articles

Co-shared genomic alterations within tumors from patients with both myeloproliferative neoplasms and lymphoma (299 Online Views)

Johanne M. Holst, Martin B. Pedersen, Marie B. Enemark, Marcus C. Hansen, Patrick R. Noerhave, Trine L. Plesner, Henrik Frederiksen, Michael B. Moeller, Stephen J. Hamilton-Dutoit, Peter Noergaard, Bo K. Mortensen, Hans B. Ommen, Jesper Stentoft, Wayne Tam, Maja Ludvigsen, Wing C. Chan, Nicolai J. Birkbak, Giorgio Inghirami, Francesco d’Amore

https://doi.org/10.3324/haematol.2023.283798

A transgenic mouse model of Down syndrome acute lymphoblastic leukemia identifies targetable vulnerabilities (277 Online Views)

Jacob J. Junco, Max Rochette, Michelle Alozie, Raushan Rashid, Maci Terrell, Barry Zorman, Pavel Sumazin, Lauren Rowland, Gino Dettorre, Reid T. Powell, Clifford C. Stephan, Peter J. Davies, Margarita Martinez-Moczygemba, Jun J. Yang, Karen R. Rabin

https://doi.org/10.3324/haematol.2023.284761

Unlocking the therapeutic potential of selective CDK7 and BRD4 Inhibition against multiple myeloma cell growth (387 Online Views)

Yao Yao, Shuhui Deng, Jessica Fong Ng, Mei Yuan, Chandraditya Chakraborty, Vera JoyWeiler, Nikhil Munshi, Mariateresa Fulciniti

https://doi.org/10.3324/haematol.2024.285491

Letters to the Editor

Increased frequency of clonal hematopoiesis of indeterminate potential in Bloom syndrome probands and carriers (266 Online Views)

Isabella Lin, Angela Wei, Tsumugi A. Gebo, Paul C. Boutros, Maeve Flanagan, Nicole Kucine, Christopher Cunniff, Valerie A. Arboleda, Vivian Y. Chang

https://doi.org/10.3324/haematol.2024.285239

Jul 18, 2024

Editorials
Article

Azacitidine as epigenetic priming for chemotherapy is safe and well-tolerated in infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia: Children’s Oncology Group trial AALL15P1 (520 Online Views)

Erin M. Guest, John A. Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew J. Carroll, Nyla A. Heerema, Holly R. Kubaney, Margaret A. August, Sidharth Ramesh, Byunggil Yoo, Midhat S. Farooqi, Melinda G. Pauly, Daniel S. Wechsler, Rodney R. Miles, Joel M. Reid, Cynthia D. Kihei, Lia Gore, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown

https://doi.org/10.3324/haematol.2024.285158

Articles

Atezolizumab combined with immunogenic salvage chemoimmunotherapy in patients with transformed diffuse large B-cell lymphoma (481 Online Views)

Tamer Othman, Paul Frankel, Pamela Allen, Leslie L. Popplewell, Geoffrey Shouse, Tanya Siddiqi, Alexey V. Danilov, Nora Ruel, Shari Daniels, Lacolle Peters, Stella Khoo, Steven T. Rosen, Elad Sharon, Miguel Villalona-Calero, Christopher Ruel, Joseph Tuscano, Alex F. Herrera

https://doi.org/10.3324/haematol.2024.285185

Multiple myeloma in the young: insights on prognosis, clinical features and treatment outcome derived from nationwide German registry data and a nested multicenter sample (479 Online Views)

Abdulaziz Kamili, Paymon Ahmadi, Lisa Leypoldt, Franziska Marquard, Christoph Schaefers, Ricardo Kosch, Frederik Peters, Henrik Kusche, Tanja Zamrik, Christine Hanoun, Maximilian Seib, Evgenii Shumilov, Theo Leitner, Cyrus Khandanpour, Carsten Bokemeyer, Katja Weisel, Susanne Ghandili

https://doi.org/10.3324/haematol.2024.285630

Risk of infections in multiple myeloma. A population-based study on 8672 multiple myeloma patients diagnosed 2008-2021 from the Swedish Myeloma Registry (444 Online Views)

Cecilie Hveding Blimark, Kristina Carlson, Christopher Day, Sigrun Einarsdottir, Gunnar Juliusson, Moshtak Karma, Dorota Knut-Bojanowska, Gunnar Larfors, Ingemar Turesson, Mariana Villegas-Scivetti, Ingigerdur Sverrisdóttir

https://doi.org/10.3324/haematol.2024.285645

Letters to the Editor

Reference interval of free light chains ratio in patients with end-stage renal disease on chronic hemodialysis (255 Online Views)

Camila Peña, Ricardo Valjalo, Ramón Pérez, Marco Álvarez, Pablo Bustamante, Esteban Forray, Viviana Balboa, Alexis Bondi

https://doi.org/10.3324/haematol.2024.285093

Co-transfection of murine NXPE2 and murine glycophorin A confers reactivity with Ter-119 (262 Online Views)

Gregory R. Keele, Ariel M. Hay, Nadia K. Holness, Arijita Jash, Sarah E. Ewald, Callan O’Connor, Matthew Vincent, Monika Dzieciatkowska, Angelo D’Alessandro, Gary A. Churchill, James C. Zimring

https://doi.org/10.3324/haematol.2024.285168

Polytypic B cells, monotypic/monoclonal B-cell proliferations, and neoplastic T cells diverge from TET2-/DNMT3A-mutant clonal hematopoiesis in follicular helper T-cell lymphomas (500 Online Views)

Natasha E. Lewis, Kseniya Petrova-Drus, Rohan Sardana, Sarah Huet, Qi Gao, Shenon Sethi, Chad Vanderbilt, Wenbin Xiao, Mikhail Roshal, Jeeyeon Baik, Himanshu Bhurtel, Alison J. Moskowitz, Steven M. Horwitz, Ahmet Dogan

https://doi.org/10.3324/haematol.2024.285183

No clear benefit of preventive cranial radiotherapy in childhood Philadelphia-positive acute lymphoblastic leukemia: a retrospective analysis of the EsPhALL2010 study (305 Online Views)

Valentino Conter, Maria Grazia Valsecchi, Paola De Lorenzo, Virginie Gandemer, Mats Heyman, Vaskar Saha, Paulina Diaz, Chi-Kong Li, Andishe Attarbaschi, Gabriele Escherich, Jan Stary, Martin Schrappe, Rob Pieters, Gunnar Cario, Andrea Biondi

https://doi.org/10.3324/haematol.2024.285253

A targeted gene signature stratifying mediastinal gray zone lymphoma into classical HL-like or PMBL-like subtypes (700 Online Views)

Grazia Gargano, Maria Carmela Vegliante, Flavia Esposito, Susanna A. Pappagallo, Elena Sabattini, Claudio Agostinelli, Stefano A. Pileri, Valentina Tabanelli, Maurilio Ponzoni, Luisa Lorenzi, Fabio Facchetti, Arianna Di Napoli, Marco Lucioni, Marco Paulli, Lorenzo Leoncini, Stefano Lazzi, Stefano Ascani, Giuseppina Opinto, Gian Maria Zaccaria, Giacomo Volpe, Paolo Mondelli, Antonella Bucci, Laura Selicato, Antonio Negri, Giacomo Loseto, Felice Clemente, Anna Scattone, Alfredo F. Zito, Luca Nassi, Nicoletta Del Buono, Attilio Guarini, Sabino Ciavarella

https://doi.org/10.3324/haematol.2024.285266

Jul 11, 2024

Editorials
Article

IKZF1 gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia (594 Online Views)

Britt M. T. Vervoort, Miriam Butler, Kari J.T. Grünewald, Dorette S. van Ingen Schenau, Trisha M. Tee, Luc Lucas, Alwin D. R. Huitema, Judith M. Boer, Beat C. Bornhauser, Jean-Pierre Bourquin, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

https://doi.org/10.3324/haematol.2023.284357

Editorials
Article

Decision analysis for transplant candidates with primary myelofibrosis in the ruxolitinib era (581 Online Views)

Yosuke Okada, Hideki Nakasone, Shunto Kawamura, Kosuke Takano, Kazuki Yoshimura, Masaharu Tamaki, Akari Matsuoka, Takuto Ishikawa, Tomohiro Meno, Yuhei Nakamura, Masakatsu Kawamura, Junko Takeshita, Nozomu Yoshino, Yukiko Misaki, Machiko Kusuda, Aki Tanihara, Shun-ichi Kimura, Shinichi Kako, Yoshinobu Kanda

https://doi.org/10.3324/haematol.2024.285256

Articles

Umbilical cord blood T cells can be isolated and enriched by CD62L selection for use in 'off the shelf' chimeric antigen receptor T-cell therapies to widen transplant options (662 Online Views)

Christos Georgiadis, Lauren Nickolay, Farhatullah Syed, Hong Zhan, Soragia Athina Gkazi, Annie Etuk, Ulrike Abramowski-Mock, Roland Preece, Piotr Cuber, Stuart Adams, Giorgio Ottaviano, Waseem Qasim

https://doi.org/10.3324/haematol.2024.285101

Combinatorial strategies targeting NEAT1 and AURKA as new potential therapeutic options for multiple myeloma (613 Online Views)

Noemi Puccio, Gloria Manzotti, Elisabetta Mereu, Federica Torricelli, Domenica Ronchetti, Michela Cumerlato, Ilaria Craparotta, Laura Di Rito, Marco Bolis, Valentina Traini, Veronica Manicardi, Valentina Fragliasso, Yvan Torrente, Nicola Amodio, Niccolò Bolli, Elisa Taiana, Alessia Ciarrocchi, Roberto Piva, Antonino Neri

https://doi.org/10.3324/haematol.2024.285470

Single-point and kinetics of peripheral residual disease by mass spectrometry to predict outcome in patients with high risk smoldering multiple myeloma included in the GEM-CESAR trial (782 Online Views)

Noemí Puig, Cristina Agulló, Teresa Contreras, José-Juan Pérez, Irene Aires, María-José Calasanz, Ramón García-Sanz, Sergio Castro, Joaquín Martínez-López, Paula Rodríguez-Otero, Verónica González-Calle, Marta S González, Albert Oriol, Norma C Gutiérrez, Rafael Ríos-Tamayo, Laura Rosiñol, Miguel-Ángel Álvarez, Joan Bargay, Ana-Pilar González-Rodríguez, Adrián Alegre, Fernando Escalante, María-Belén Iñigo, Javier de la Rubia, Ana-Isabel Teruel, Felipe de Arriba, Luis Palomera, Miguel T Hernández, Javier López-Jiménez, Marta Reinoso, Aránzazu García-Mateo, Enrique M Ocio, Joan Bladé, Juan-José Lahuerta, María-Teresa Cedena, Bruno Paiva, Jesús F San Miguel, María-Victoria Mateos

https://doi.org/10.3324/haematol.2024.285742

Letters to the Editor

Rituximab maintenance after bendamustine-based treatment for follicular lymphoma and mantle cell lymphoma may exert a negative influence on SARS-CoV-2 infection outcomes (498 Online Views)

Ángel Serna, Víctor Navarro, Gloria Iacoboni, Laia López, Juan-Manuel Sancho, Eva González-Barca, Alberto López-García, Raúl Córdoba, Adolfo Sáez, Ana Jiménez Ubieto, Ainara Ferrero, Tomás García, Ángela Sánchez, Cristina García, Marc Bosch, Alba Cabirta, Moraima Jiménez, Ana Marín-Niebla, Francesc Bosch, Pau Abrisqueta

https://doi.org/10.3324/haematol.2024.285219

Excellent outcome of children/adolescents with primary mediastinal large B-cell lymphoma treated with FAB/LMB-based chemotherapy regimen with rituximab (361 Online Views)

Marie Emilie Dourthe, Anne Auperin, Charlotte Rigaud, Melissa Barbati, Jacinthe Bonneau, Nimrod Buchbinder, Marie-Laure Couec, Peggy Dartigues, Stéphane Ducassou, Nathalie Garnier, Stéphanie Haouy, Bénédicte Jonca, Anne Jourdain, Amaury Leruste, Thierry Molina, Françoise Montravers, Marlène Pasquet, Aurélie Phulpin, Maryline Poirée, Mathieu Simonin, Alexandra Spiegel, Arnauld Verschuur, Thierry Leblanc, Judith Landman-Parker, Catherine Patte, Véronique Minard-Colin

https://doi.org/10.3324/haematol.2024.285403

Microbiota signature of oral chronic graft-versus-host disease 6+ years after transplantation (335 Online Views)

Armin Rashidi, Lang Liang, Ted Gooley, Philippe P. Hujoel, Alex Zevin, Marilynn Rothen, Mary K. Hagstrom, Corey Cutler, Stephanie J. Lee, David R. Dean, Hervé Y. Sroussi, Nathaniel S. Treister

https://doi.org/10.3324/haematol.2024.285650

Extending duration of letermovir prophylaxis in haploidentical stem cell transplantation (363 Online Views)

Pongthep Vittayawacharin, Benjamin J. Lee, Shawn Griffin, Jean Doh, Julie Smith, Hannah Nam, Emily Blodget, Deepa Jeyakumar, Piyanuch Kongtim, Stefan O. Ciurea

https://doi.org/10.3324/haematol.2024.285766

Comments

Jul 4, 2024

Editorials
Article

Outcomes and genetic dynamics of acute myeloid leukemia at first relapse (1317 Online Views)

Alex Bataller, Hagop Kantarjian, Alexandre Bazinet, Tapan Kadia, Naval Daver, Courtney D. DiNardo, Gautam Borthakur, Sanam Loghavi, Keyur Patel, Guilin Tang, Koji Sasaki, Nicholas J. Short, Musa Yilmaz, Ghayas C. Issa, Yesid Alvarado, Guillermo Montalban-Bravo, Abhishek Maiti, Hussein A. Abbas, Koichi Takahashi, Sherry Pierce, Elias Jabbour, Guillermo Garcia-Manero, Farhad Ravandi

https://doi.org/10.3324/haematol.2024.285057

Articles

A novel role of AURKA kinase in erythroblast enucleation (530 Online Views)

Yuanlin Xu, Peijun Jia, Yating Li, Huan Zhang, Jingxin Zhang, Wanxin Li, Yazhe Zhen, Yan Li, Jiaming Cao, Tingting Zheng, Yihan Wang, Yanyan Liu, Xiuli An, Shijie Zhang

https://doi.org/10.3324/haematol.2023.284873

LSD1/KDM1A and GFI1B repress endothelial fate and induce hematopoietic fate in induced pluripotent stem cell-derived hemogenic endotheliums (603 Online Views)

Huan Zhang, Marten Hansen, Franca di Summa, Marieke von Lindern, Nynke Gillemans, Wilfred F.J. van IJcken, Arthur Flohr Svendsen, Sjaak Philipsen, Bert van der Reijden, Eszter Varga, Emile van den Akker

https://doi.org/10.3324/haematol.2024.285214

Letters to the Editor

Response to DA-EPOCH-R is associated with activation of 'fitter' cytotoxic T-cells in patients with newly diagnosed double and triple hit high-grade B-cell lymphoma (388 Online Views)

A. Vera de Jonge, Wassilis S.C. Bruins, Carolien Duetz, Charlotte L.B.M. Korst, Rosa Rentenaar, Meliha Cosovic, Merve Eken, Marie-Jose Kersten, Yorick Sandberg, Rozemarijn S. van Rijn, Rob Fijnheer, Pim Mutsaers, Vibeke K.J. Vergote, Djamila Issa, Aart Beeker, Yavuz M. Bilgin, Otto Visser, Erik van Werkhoven, Margaretha G.M. Roemer, Martine E.D. Chamuleau, Tuna Mutis

https://doi.org/10.3324/haematol.2024.285170

Case Reports

Jun 27, 2024

Articles

Core regions in immunoglobulin heavy chain enhancers essential for survival of non-Hodgkin lymphoma cells are identified by a CRISPR interference screen (551 Online Views)

Marta Elżbieta Kasprzyk, Weronika Sura, Marta Podralska, Marta Kazimierska, Annika Seitz, Wojciech Łosiewski, Tomasz Woźniak, Jeroen E. J. Guikema, Arjan Diepstra, Joost Kluiver, Anke van den Berg, Natalia Rozwadowska, Agnieszka Dzikiewicz-Krawczyk

https://doi.org/10.3324/haematol.2023.284672

Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia (714 Online Views)

Mohd Minhajuddin, Amanda Winters, Haobin Ye, Shanshan Pei, Brett Stevens, Austin Gillen, Krysta Engel, Stephanie Gipson, Monica Ransom, Maria Amaya, Anagha Inguva, Maura Gasparetto, Mark J. Althoff, Regan Miller, Ian Shelton, Hunter Tolison, Anna Krug, Rachel Culp-Hill, Angelo D’Alessandro, Daniel W Sherbenou, Daniel A. Pollyea, Clayton Smith, Craig T Jordan

https://doi.org/10.3324/haematol.2023.284716

Blockade of the CD47/SIRPα checkpoint axis potentiates the macrophage-mediated anti-tumor efficacy of tafasitamab (795 Online Views)

Alexander Biedermann, Maria Patra-Kneuer, Dimitrios Mougiakakos, Maike Büttner-Herold, Doris Mangelberger-Eberl, Johannes Berges, Christian Kellner, Sarah Altmeyer, Jörg Thomas Bittenbring, Christian Augsberger, Kristina Ilieva-Babinsky, Stefan Haskamp, Fabian Beier, Christopher Lischer, Julio Vera, Anja Lührmann, Simone Bertz, Simon Völkl, Benedikt Jacobs, Stefan Steidl, Andreas Mackensen, Heiko Bruns

https://doi.org/10.3324/haematol.2023.284795

Safety and efficacy of flumatinib as later-line therapy in patients with chronic myeloid leukemia (551 Online Views)

Yunfan Yang, Yuntao Liu, Hui Sun, Li Meng, Hai Lin, Chunyan Chen, Jianda Hu, Xuliang Shen, Minghui Duan, Yanli Zhang, Dilinazi Abulaiti, Jinghua Wang, Hongqian Zhu, Luoming Hua, Qing Leng, Chun Zhang, Lili Sun, Weiming Li, Huanling Zhu, Bingcheng Liu, Jianxiang Wang

https://doi.org/10.3324/haematol.2023.284892

Letters to the Editor

Respiratory syncytial virus and other vaccine-preventable infections in Multiple Myeloma. A population-based study on 8672 myeloma patients diagnosed 2008-2021 from the Swedish Myeloma Registry (340 Online Views)

Sigrun Einarsdottir, Ingigerdur Sverrisdottir, Mariana Villegas-Scivetti, Chris Day, Ingemar Turesson, Gunnar Juliusson, Markus Hansson, Gunnar Larfors, Cecilie Hveding Blimark

https://doi.org/10.3324/haematol.2024.285161

Comments

Jun 20, 2024

Articles

A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers (761 Online Views)

Filippo Spriano, Giulio Sartori, Jacopo Sgrignani, Laura Barnabei, Alberto J. Arribas, Matilde Guala, Ana Maria Carrasco Del Amor, Meagan R. Tomasso, Chiara Tarantelli, Luciano Cascione, Gaetanina Golino, Maria E Riveiro, Roberta Bortolozzi, Antonio Lupia, Francesco Paduano, Samuel Huguet, Keyvan Rezai, Andrea Rinaldi, Francesco Margheriti, Pedro Ventura, Greta Guarda, Giosuè Costa, Roberta Rocca, Alberto Furlan, Luuk M. Verdonk, Paolo Innocenti, Nathaniel I. Martin, Giampietro Viola, Christoph Driessen, Emanuele Zucca, Anastasios Stathis, Digvijay Gahtory, Maurits van den Nieuwboer, Beat Bornhauser, Stefano Alcaro, Francesco Trapasso, Susana Cristobal, Shae B. Padrick, Natalina Pazzi, Franco Cavalli, Andrea Cavalli, Eugenio Gaudio, Francesco Bertoni

https://doi.org/10.3324/haematol.2022.282672

Anti-CD19 chimeric antigen receptor T-cell therapy has less efficacy in Richter transformation than in de novo large B-cell lymphoma and transformed low-grade B-cell lymphoma (897 Online Views)

Ohad Benjamini, Shalev Fried, Roni Shouval, Jessica R. Flynn, Ofrat Beyar-Katz, Lori A Leslie, Tsilla Zucherman, Ronit Yerushalmi, Noga Shem-Tov, Maria Lia Palomba, Ivetta Danylesko, Inbal Sdayoor, Hila Malka, Orit Itzhaki, Hyung Suh, Sean M. Devlin, Ronit Marcus, Parastoo B Dahi, Elad Jacoby, Gunjan L Shah, Craig S Sauter, Andrew Ip, Miguel-Angel Perales, Arnon Nagler, Avichai Shimoni, Michael Scordo, Abraham Avigdor

https://doi.org/10.3324/haematol.2023.284664

Brexucabtagene autoleucel in relapsed or refractory mantle cell lymphoma, intention-to-treat use in the DESCAR-T registry (638 Online Views)

Charles Herbaux, Caroline Bret, Emmanuel Bachy, Pierre Bories, Roberta Di Blasi, Alexis Cuffel, Thomas Gastinne, Thierry Lamy, Mikael Roussel, Krimo Bouabdallah, David Beauvais, Guillaume Cartron, Jacques-Olivier Bay, Didier Blaise, Marie-Therese Rubio, Mohamad Mohty, Fabien Le Bras, Olivier Casasnovas, Julien Guy, Stephanie Guidez, Cristina Castilla Llorente, Olivier Hermine, Laurianne Drieu La Rochelle, Sylvain Carras, Blandine Guffroy, Sophie Caillat-Zucman, Roch Houot, Steven Le Gouill

https://doi.org/10.3324/haematol.2023.284786

Decision analysis for transplant candidates with primary myelofibrosis in the ruxolitinib era (581 Online Views)

Yosuke Okada, Hideki Nakasone, Shunto Kawamura, Kosuke Takano, Kazuki Yoshimura, Masaharu Tamaki, Akari Matsuoka, Takuto Ishikawa, Tomohiro Meno, Yuhei Nakamura, Masakatsu Kawamura, Junko Takeshita, Nozomu Yoshino, Yukiko Misaki, Machiko Kusuda, Aki Tanihara, Shun-ichi Kimura, Shinichi Kako, Yoshinobu Kanda

https://doi.org/10.3324/haematol.2024.285256

Letters to the Editor

FLT3 inhibitors potentially improve response rates in acute myeloid leukemia harboring t(6;9)(DEK::NUP214): The Mayo Clinic experience (209 Online Views)

Clifford M. Csizmar, Antoine N. Saliba, Patricia T. Greipp, Hassan Alkhateeb, Kebede H. Begna, James M. Foran, Naseema Gangat, William J. Hogan, C. Christopher Hook, Mark R. Litzow, Abhishek A. Mangaonkar, Jeanne M. Palmer, Animesh Pardanani, Mithun V. Shah, Ayalew Tefferi, Mehrdad Hefazi Torghabeh, Alexandra P. Wolanskyj-Spinner, Mrinal M. Patnaik, Scott H Kaufmann, Aref Al-Kali

https://doi.org/10.3324/haematol.2024.285359

Jun 13, 2024

Articles

Event-free survival at 36 months is a suitable endpoint for diffuse large B-cell lymphoma patients treated with immunochemotherapy: real-world evidence from the North Japan Hematology Study Group (685 Online Views)

Koh Izumiyama, Tasuku Inao, Hideki Goto, Shinpei Harada, Hajime Senjo, Keito Suto, Junichi Hashiguchi, Reiki Ogasawara, Tomoyuki Saga, Tetsuyuki Igarashi, Kentaro Wakasa, Ikumi Kasahara, Yukari Takeda, Keisuke Yamaguchi, Akio Shigematsu, Mutsumi Takahata, Katsuya Fujimoto, Yoshihito Haseyama, Takahiro Nagashima, Hajime Sakai, Yasutaka Kakinoki, Mitsutoshi Kurosawa, Isao Yokota, Takanori Teshima

https://doi.org/10.3324/haematol.2023.284841

Azacitidine as epigenetic priming for chemotherapy is safe and well-tolerated in infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia: Children’s Oncology Group trial AALL15P1 (520 Online Views)

Erin M. Guest, John A. Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew J. Carroll, Nyla A. Heerema, Holly R. Kubaney, Margaret A. August, Sidharth Ramesh, Byunggil Yoo, Midhat S. Farooqi, Melinda G. Pauly, Daniel S. Wechsler, Rodney R. Miles, Joel M. Reid, Cynthia D. Kihei, Lia Gore, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown

https://doi.org/10.3324/haematol.2024.285158

Jun 6, 2024

Articles

Epstein-Barr Virus and immune status imprint the immunogenomics of non-Hodgkin lymphomas occurring in immune-suppressed environments (719 Online Views)

Marine Baron, Karim Labreche, Marianne Veyri, Nathalie Désiré, Amira Bouzidi, Fatou Seck-Thiam, Frédéric Charlotte, Alice Rousseau, Véronique Morin, Cécilia Nakid-Cordero, Baptiste Abbar, Alberto Picca, Marie Le Cann, Noureddine Balegroune, Nicolas Gauthier, Ioannis Theodorou, Mehdi Touat, Véronique Morel, Franck Bielle, Assia Samri, Agusti Alentorn, Marc Sanson, Damien Roos-Weil, Corinne Haioun, Elsa Poullot, Anne Langlois de Septenville, Frédéric Davi, Amélie Guihot, Pierre-Yves Boelle, Véronique Leblond, Florence Coulet, Jean-Philippe Spano, Sylvain Choquet, Brigitte Autran; IDeATIon study group (Collaborative Group)

https://doi.org/10.3324/haematol.2023.284332

IKZF1 gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia (594 Online Views)

Britt M. T. Vervoort, Miriam Butler, Kari J.T. Grünewald, Dorette S. van Ingen Schenau, Trisha M. Tee, Luc Lucas, Alwin D. R. Huitema, Judith M. Boer, Beat C. Bornhauser, Jean-Pierre Bourquin, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

https://doi.org/10.3324/haematol.2023.284357

Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma (864 Online Views)

Nicholas Davies, Tegan Francis, Ceri Oldreive, Maria Azam, Jordan Wilson, Philip J. Byrd, Megan Burley, Archana Sharma-Oates, Peter Keane, Sael Alatawi, Martin R. Higgs, Zbigniew Rudzki, Maha Ibrahim, Tracey Perry, Angelo Agathanggelou, Anne-Marie Hewitt, Edward Smith, Constanze Bonifer, Mark O’Connor, Josep V. Forment, Paul G. Murray, Eanna Fennell, Gemma Kelly, Catherine Chang, Grant S. Stewart, Tatjana Stankovic, Marwan Kwok, Alexander Malcolm Taylor

https://doi.org/10.3324/haematol.2023.284404

Asciminib stands out as the superior tyrosine kinase inhibitor to combine with anti-CD20 monoclonal antibodies for the treatment of CD20+ Philadelphia-positive B-cell precursor acute lymphoblastic leukemia in preclinical models (743 Online Views)

Krzysztof Domka, Agnieszka Dąbkowska, Martyna Janowska, Zuzanna Urbańska, Agata Pastorczak, Magdalena Winiarska, Klaudyna Fidyt, Mieszko Lachota, Elżbieta Patkowska, Łukasz Sędek, Bartosz Perkowski, Jaromir Hunia, Justyna Jakubowska, Beata Krzymieniewska, Ewa Lech-Marańda, Wojciech Młynarski, Tomasz Szczepański, Małgorzata Firczuk

https://doi.org/10.3324/haematol.2023.284853

Impact of genetic alterations on central nervous system progression of primary vitreoretinal lymphoma (551 Online Views)

Kota Yoshifuji, Daichi Sadato, Takashi Toya, Yotaro Motomura, Chizuko Hirama, Hiroshi Takase, Kouhei Yamamoto, Yuka Harada, Takehiko Mori, Toshikage Nagao

https://doi.org/10.3324/haematol.2023.284953

Superior outcomes and high-risk features with carfilzomib, lenalidomide, and dexamethasone combination therapy for patients with relapsed and refractory multiple myeloma: Results of the multicenter KMMWP2201 study (663 Online Views)

Ji Hyun Lee, Jimin Choi, Chang-Ki Min, Sung-Soo Park, Jae-Cheol Jo, Yoo Jin Lee, Jin Seok Kim, Hyeon-Seok Eom, Jongheon Jung, Joon Ho Moon, Hee Jeong Cho, Myung-won Lee, Sung-Soo Yoon, Ja Min Byun, Jae Hoon Lee, Je-Jung Lee, Sung-Hoon Jung, Ho-Jin Shin, Do Young Kim, Jun Ho Yi, Seung-Shin Lee, Young Rok Do, Dok Hyun Yoon, Hyungwoo Cho, Won Sik Lee, Ho Sup Lee, Jieun Uhm, Hyo Jung Kim, Hee Ryeong Jang, Sung-Hyun Kim, Kihyun Kim

https://doi.org/10.3324/haematol.2024.285534

May 30, 2024

Articles

The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival (616 Online Views)

Vesna S. Stanulović, Shorog Al Omair, Michelle A.C. Reed, Jennie Roberts, Sandeep Potluri, Taylor Fulton-Ward, Nancy Gudgeon, Emma L. Bishop, Juliette Roels, Tracey A. Perry, Sovan Sarkar, Guy Pratt, Tom Taghon, Sarah Dimeloe, Ulrich L. Günther, Christian Ludwig, Maarten Hoogenkamp

https://doi.org/10.3324/haematol.2023.283471

Deep phenotyping of nodal T-cell lymphomas reveals immune alterations and therapeutic targets (523 Online Views)

Pierre Stephan, Jimmy Perrot, Allison Voisin, Maud Barbery, Thibault Andrieu, Maxime Grimont, Julie Caramel, Mathilde Bardou, Garance Tondeur, Edoardo Missiaglia, Philippe Gaulard, François Lemmonier, Laurence de Leval, Emmanuel Bachy, Pierre Sujobert, Laurent Genestier, Alexandra Traverse-Glehen, Yenkel Grinberg-Bleyer

https://doi.org/10.3324/haematol.2023.284448

Management of complications of chimeric antigen receptor T-cell therapy: a report by the European Society of Blood and Marrow Transplantation (975 Online Views)

Olaf Penack, Christophe Peczynski, William Boreland, Daniel Wolff, Ivan Moiseev, Hélène Schoemans, Christian Koenecke, Charlotte Graham, Zinaida Peric

https://doi.org/10.3324/haematol.2023.284810

Prognostic impact of ‘multi-hit’ versus ‘single hit’ TP53 alteration in patients with acute myeloid leukemia: results from the Consortium on Myeloid Malignancies and Neoplastic Diseases (1147 Online Views)

Talha Badar, Ahmad Nanaa, Ehab Atallah, Rory M. Shallis, Emily C. Craver, Zhuo Li, Aaron D. Goldberg, Antoine N. Saliba, Anand Patel, Jan P. Bewersdorf, Adam Duvall, Madelyn Burkart, Danielle Bradshaw, Yasmin Abaza, Maximilian Stahl, Neil Palmisiano, Guru Subramanian Guru Murthy, Amer M. Zeidan, Vamsi Kota, Mrinal M. Patnaik, Mark R. Litzow

https://doi.org/10.3324/haematol.2024.285000

LILRB4 represents a promising target for immunotherapy by dual targeting tumor cells and myeloid-derived suppressive cells in multiple myeloma (1182 Online Views)

Lixin Gong, Hao Sun, Lanting Liu, Xiyue Sun, Teng Fang, Zhen Yu, Weiwei Sui, Jingyu Xu, Tingyu Wang, Fangshuo Feng, Lei Lei, Wei Rui, Yuxuan Liu, Xueqiang Zhao, Gang An, Xin Lin, Lugui Qiu, Mu Hao

https://doi.org/10.3324/haematol.2024.285099

The role of PALLD-STAT3 interaction in megakaryocyte differentiation and thrombocytopenia treatment (590 Online Views)

Guoming Li, Haojie Jiang, Lingbin Wang, Tingting Liang, Chen Ding, Mina Yang, Yingzhi Shen, Min Xin, Lin Zhang, Jing Dai, Xueqing Sun, Xuejiao Chen, Junling Liu, Yanyan Xu

https://doi.org/10.3324/haematol.2024.285242

Case Reports

Late-onset NPM1 mutation in a MYC-amplified relapsed/refractory acute myeloid leukemia patient treated with gemtuzumab ozogamicin and glasdegib (544 Online Views)

Sonia Jaramillo, Michael Scherer, Chelsea Szu-Tu, Sergi Beneyto-Calabuig, Carsten Müller-Tidow, Richard F. Schlenk, Michael Hundemer, Lars Velten, Caroline Pabst

https://doi.org/10.3324/haematol.2023.284922

Myeloid neoplasm with histiocytosis and spleen tyrosine kinase fusion responds to fostamatinib (489 Online Views)

Zachary Risch, Benjamin H. Kaffenberger, Catherine G. Chung, Eric Samorodnitsky, Emily L. Hoskins, Thuy Dao, Amy Smith, Sarah A. Wall, Jonathan Brammer, Julie W. Reeser, Michele R. Wing, Julia F. Hopkins, Lee A. Albacker, Lynne V. Abruzzo, Caprice D. Eisele, Aharon G. Freud, Sameek Roychowdhury, Katherine E. Walsh

https://doi.org/10.3324/haematol.2024.285146

May 16, 2024

Editorials

Editorials
Letter to the Editor

Expedited evaluation of hereditary hematopoietic malignancies in the setting of stem cell transplantation (704 Online Views)

Gregory W. Roloff, Satyajit Kosuri, Mariam T. Nawas, Adam S. DuVall, Anand A. Patel, Peter A. Riedell, Olatoyosi Odenike, Wendy Stock, Richard A. Larson, Michael R. Bishop, Emma Nunley, Lucy A. Godley, Feighanne Hathaway, Daniela del Gaudio, Soma Das, Lorraine E. Canham, Michael W. Drazer

https://doi.org/10.3324/haematol.2023.284584

May 9, 2024

Editorials
Article

HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells (770 Online Views)

Tamara De Vos, Nicole Oatman, Lena Boehme, Tom Putteman, Imke Velghe, Yana Van Droogenbroeck, Stijn De Munter, Michaela Cesnekova, Filip Van Nieuwerburgh, Bart Vandekerckhove, Jan Philippe, Tom Taghon

https://doi.org/10.3324/haematol.2023.283432

May 2, 2024

Articles

Outcomes and genetic dynamics of acute myeloid leukemia at first relapse (1317 Online Views)

Alex Bataller, Hagop Kantarjian, Alexandre Bazinet, Tapan Kadia, Naval Daver, Courtney D. DiNardo, Gautam Borthakur, Sanam Loghavi, Keyur Patel, Guilin Tang, Koji Sasaki, Nicholas J. Short, Musa Yilmaz, Ghayas C. Issa, Yesid Alvarado, Guillermo Montalban-Bravo, Abhishek Maiti, Hussein A. Abbas, Koichi Takahashi, Sherry Pierce, Elias Jabbour, Guillermo Garcia-Manero, Farhad Ravandi

https://doi.org/10.3324/haematol.2024.285057

Apr 11, 2024

Articles

Letters to the Editor

Expedited evaluation of hereditary hematopoietic malignancies in the setting of stem cell transplantation (704 Online Views)

Gregory W. Roloff, Satyajit Kosuri, Mariam T. Nawas, Adam S. DuVall, Anand A. Patel, Peter A. Riedell, Olatoyosi Odenike, Wendy Stock, Richard A. Larson, Michael R. Bishop, Emma Nunley, Lucy A. Godley, Feighanne Hathaway, Daniela del Gaudio, Soma Das, Lorraine E. Canham, Michael W. Drazer

https://doi.org/10.3324/haematol.2023.284584

Apr 4, 2024

Articles

HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells (770 Online Views)

Tamara De Vos, Nicole Oatman, Lena Boehme, Tom Putteman, Imke Velghe, Yana Van Droogenbroeck, Stijn De Munter, Michaela Cesnekova, Filip Van Nieuwerburgh, Bart Vandekerckhove, Jan Philippe, Tom Taghon

https://doi.org/10.3324/haematol.2023.283432

Soluble B-cell maturation antigen in lacrimal fluid as a potential biomarker and mediator of keratopathy in multiple myeloma (1024 Online Views)

Umair Munawar, Johanna Theuersbacher, Maximilian J. Steinhardt, Xiang Zhou, Seungbin Han, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Thorsten Keller, Ann-Katrin Regensburger, Eva Teufel, Julia Mersi, Max Bittrich, Franziska Seifert, Malik S. Haider, Leo Rasche, Jost Hillenkamp, Hermann Einsele, Daniel Kampik, K. Martin Kortüm, Johannes M. Waldschmidt

https://doi.org/10.3324/haematol.2024.285205

Mar 28, 2024

Letters to the Editor

Mar 7, 2024

Perspective Articles

Feb 22, 2024

Editorials
Article

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma (1499 Online Views)

Stien De Coninck, Renate De Smedt, Beatrice Lintermans, Lindy Reunes, Hansen J. Kosasih, Alexandra Reekmans, Lauren M. Brown, Nadine Van Roy, Bruno Palhais, Juliette Roels, Malaika Van der Linden, Jo Van Dorpe, Panagiotis Ntziachristos, Frederik W. van Delft, Marc R. Mansour, Tim Pieters, Tim Lammens, Barbara De Moerloose, Charles E. de Bock, Steven Goossens, Pieter Van Vlierberghe

https://doi.org/10.3324/haematol.2023.283981

Feb 15, 2024

Guidelines

Approaches for bridging therapy prior to chimeric antigen receptor T cells for relapsed/refractory acute lymphoblastic B-lineage leukaemia in children and young adults (915 Online Views)

Tobias Feuchtinger, Peter Bader, Marion Subklewe, Maike Breidenbach, Semjon Willier, Markus Metzler, Nicola Gökbuget, Julia Hauer, Fabian Müller, Paul-Gerhardt Schlegel, Michael Frühwald, Christoph Schmid, Anja Troeger, Claudia Baldus, Roland Meisel, Annette Künkele, Max Topp, Jean-Pierre Bourquin, Gunnar Cario, Arend von Stackelberg, Christina Peters

https://doi.org/10.3324/haematol.2023.283780

Dec 14, 2023

Guidelines

Aug 19, 2021

Errata Corrige

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma (3725 Online Views)

Johannes Duell, Kami J. Maddocks, Eva González-Barca, Wojciech Jurczak, Anna Marina Liberati, Sven de Vos, Zsolt Nagy, Aleš Obr, Gianluca Gaidano, Pau Abrisqueta, Nagesh Kalakonda, Marc André, Martin Dreyling, Tobias Menne, Olivier Tournilhac, Marinela Augustin, Andreas Rosenwald, Maren Dirnberger-Hertweck, Johannes Weirather, Sumeet Ambarkhane, Gilles Salles

https://doi.org/10.3324/haematol.2021.279802

May 10, 2018

Articles

GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells (1434 Online Views)

Beibei Zhang, Pilar Ayuda Durán, Laure Piechaczyk, Yngvar Fløisand, Mireia Mayoral Safont Safont, Ida Tveit Karlsen, Zina Fandalyuk, Dagim Tadele, Pepijn van Mierlo, Alexander D. Rowe, Joseph M. Robertson, Bjørn Tore Gjertsen, Emmet McCormack, Jorrit M. Enserink, Bjørn Tore Gjertsen Group, Emmet McCormack Group

https://doi.org/10.3324/haematol.2018.189399