Early view

Apr 11, 2024

Editorial
Article

Enhancement of PRMT6 binding to a novel germline GATA1 mutation associated with congenital anemia (322 Online Views)

Yingsi Lu, Qingqing Zhu, Yun Wang, Meiling Luo, Junbin Huang, Qian Liang, Lifen Huang, Jing Ouyang, Chenxin Li, Nannan Tang, Yan Li, Tingting Kang, Yujia Song, Xiaoyu Xu, Liping Ye, Guoxing Zheng, Chun Chen, Chengming Zhu

https://doi.org/10.3324/haematol.2023.284183

Editorial
Article

Germline bi-allelic SH2B3/LNK alteration predisposes to a neonatal juvenile myelomonocytic leukemia-like disorder (601 Online Views)

Chloé Arfeuille, Yoann Vial, Margaux Cadenet, Aurélie Caye-Eude, Odile Fenneteau, Quentin Neven, Adeline A Bonnard, Simone Pizzi, Giovanna Carpentieri, Yline Capri, Katia Girardi, Lucia Pedace, Marina Macchiaiolo, Kamel Boudhar, Monia ben Khaled, Wadih Abou Chahla, Anne Lutun, Mony Fahd, Séverine Drunat, Elisabetta Flex, Jean-Hugues Dalle, Marion Strullu, Franco Locatelli, Marco Tartaglia, Hélène Cavé

https://doi.org/10.3324/haematol.2023.283917
Article

LNK/SH2B3 as a novel driver in juvenile myelomonocytic leukemia (713 Online Views)

Astrid Wintering, Anna Hecht, Julia Meyer, Eric B. Wong, Juwita Hübner, Sydney Abelson, Kira Feldman, Vanessa E. Kennedy, Cheryl A.C. Peretz, Deborah L. French, Jean Ann Maguire, Chintan Jobaliya, Marta Rojas Vasquez, Sunil Desai, Robin Dulman, Eneida Nemecek, Hilary Haines, Mahmoud Hammad, Alaa El Haddad, Scott C. Kogan, Zied Abdullaev, Farid F. Chehab, Sarah K. Tasian, Catherine C. Smith, Mignon L. Loh, Elliot Stieglitz

https://doi.org/10.3324/haematol.2023.283776

Review Articles

Articles

Letters to the Editor

Expedited evaluation of hereditary hematopoietic malignancies in the setting of stem cell transplantation (182 Online Views)

Gregory W. Roloff, Satyajit Kosuri, Mariam T. Nawas, Adam S. DuVall, Anand A. Patel, Peter A. Riedell, Olatoyosi Odenike, Wendy Stock, Richard A. Larson, Michael R. Bishop, Emma Nunley, Lucy A. Godley, Feighanne Hathaway, Daniela del Gaudio, Soma Das, Lorraine E. Canham, Michael W. Drazer

https://doi.org/10.3324/haematol.2023.284584

Molecular responses in decitabine- and decitabine/venetoclax-treated patients with acute myeloid leukemia and myelodysplastic syndromes (21 Online Views)

Agata Gruszczynska, Abhishek Maiti, Christopher A. Miller, Sai Mukund Ramakrishnan, Daniel C. Link, Geoffrey L. Uy, Allegra A. Petti, Kala Hayes, Courtney D. DiNardo, Farhad Ravandi, Timothy J. Ley, David H. Spencer, Feng Gao, Marina Y. Konopleva, John S. Welch

https://doi.org/10.3324/haematol.2022.281396

Apr 4, 2024

Editorials
Article

ETV6::ACSL6 translocation-driven super-enhancer activation leads to eosinophilia in acute lymphoblastic leukemia through IL-3 overexpression (492 Online Views)

Wenqian Xu, Feng Tian, Xiaolu Tai, Gaoxian Song, Yuanfang Liu, Liquan Fan, Xiangqin Weng, Eunjeong Yang, Meng Wang, Martin Bornhäuser, Chao Zhang, Richard B. Lock, Jason W.H. Wong, Jin Wang, Duohui Jing, Jian-Qing Mi

https://doi.org/10.3324/haematol.2023.284121

Articles

CD9 shapes glucocorticoid sensitivity in pediatric B-cell precursor acute lymphoblastic leukemia (235 Online Views)

Chi Zhang, Kathy Yuen Yee Chan, Wing Hei Ng, John Tak Kit Cheung, Qiwei Sun, Han Wang, Po Yee Chung, Frankie Wai Tsoi Cheng, Alex Wing Kwan Leung, Xiao-Bing Zhang, Po Yi Lee, Siu Ping Fok, Guanglan Lin, Ellen Ngar Yun Poon, Jian-Hua Feng, Yan-Lai Tang, Xue-Qun Luo, Li-Bin Huang, Wei Kang, Patrick Ming Kuen Tang, Junbin Huang, Chun Chen, Junchao Dong, Ester Mejstrikova, Jiaoyang Cai, Yu Liu, Shuhong Shen, Jun J Yang, Patrick Man Pan Yuen, Chi Kong Li, Kam Tong Leung

https://doi.org/10.3324/haematol.2023.282952

HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells (221 Online Views)

Tamara De Vos, Nicole Oatman, Lena Boehme, Tom Putteman, Imke Velghe, Yana Van Droogenbroeck, Stijn De Munter, Michaela Cesnekova, Filip Van Nieuwerburgh, Bart Vandekerckhove, Jan Philippe, Tom Taghon

https://doi.org/10.3324/haematol.2023.283432

Hematopoiesis post anti-CD117 monoclonal antibody treatment in wild-type and Fanconi anemia settings (214 Online Views)

Morgane Denis, Leah Swartzrock, Hana Willner, Quenton R. Bubb, Ethan Haslett, Yan Yi Chan, Anzhi Chen, Mark R. Krampf, Agnieszka D. Czechowicz

https://doi.org/10.3324/haematol.2023.284275

Endurance training improves oxygen uptake/demand mismatch, metabolic flexibility and recovery in patients with sickle cell disease (160 Online Views)

Loïs Mougin, Manon Riccetti, Angèle N. Merlet, Pablo Bartolucci, Barnabas Gellen, Léo Blervaque, Thomas d’Humières, Frédéric Galactéros, Chi-An W. Emhoff, Léonard Féasson, Laurent A. Messonnier

https://doi.org/10.3324/haematol.2023.284474

Mutual regulation of CD4+ T cells and intravascular fibrin in infections (194 Online Views)

Tonina T. Mueller, Mona Pilartz, Manovriti Thakur, Torben LangHeinrich, Junfu Luo, Rebecca Block, Jonathan K.L. Hoeflinger, Sarah Meister, Flavio Karaj, Laura Garcia Perez, Rupert Öllinger, Thomas Engleitner, Jakob Thoss, Michael Voelkl, Claudia Tersteeg, Uwe Koedel, Alexander Zigman Kohlmaier, Daniel Teupser, Malgorzata Wygrecka, Haifeng Ye, Klaus T. Preissner, Helena Radbruch, Sefer Elezkurtaj, Matthias Mack, Philipp von Hundelshausen, Christian Weber, Steffen Massberg, Christian Schulz, Roland Rad, Samuel Huber, Hellen Ishikawa-Ankerhold, Bernd Engelmann

https://doi.org/10.3324/haematol.2023.284619

A phase I study of pevonedistat, azacitidine, and venetoclax in patients with relapsed/refractory acute myeloid leukemia (229 Online Views)

Guru Subramanian Guru Murthy, Antoine N. Saliba, Aniko Szabo, Alexandra Harrington, Sameem Abedin, Karen Carlson, Laura Michaelis, Lyndsey Runaas, Arielle Baim, Alex Hinman, Sonia Maldonado-Schmidt, Annapoorna Venkatachalam, Karen S. Flatten, Kevin L. Peterson, Paula A. Schneider, Mark Litzow, Scott H. Kaufmann, Ehab Atallah

https://doi.org/10.3324/haematol.2024.285014

Soluble B-cell maturation antigen in lacrimal fluid as a potential biomarker and mediator of keratopathy in multiple myeloma (279 Online Views)

Umair Munawar, Johanna Theuersbacher, Maximilian J. Steinhardt, Xiang Zhou, Seungbin Han, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Thorsten Keller, Ann-Katrin Regensburger, Eva Teufel, Julia Mersi, Max Bittrich, Franziska Seifert, Malik S. Haider, Leo Rasche, Jost Hillenkamp, Hermann Einsele, Daniel Kampik, K. Martin Kortüm, Johannes M. Waldschmidt

https://doi.org/10.3324/haematol.2024.285205

Letters to the Editor

Sotatercept for anemia of myelofibrosis: a phase II investigator-initiated study (241 Online Views)

Prithviraj Bose, Lucia Masarova, Naveen Pemmaraju, Sharon D. Bledsoe, Naval G. Daver, Elias J. Jabbour, Tapan M. Kadia, Zeev Estrov, Steven M. Kornblau, Michael Andreeff, Nitin Jain, Jorge E. Cortes, Gautam Borthakur, Yesid Alvarado, Mary Ann Richie, Mackenzie H. Dobbins, Selene A. McCrackin, Lingsha Zhou, Sherry A. Pierce, Xuemei Wang, Allison M. Pike, Guillermo Garcia-Manero, Hagop M. Kantarjian, Srdan Verstovsek

https://doi.org/10.3324/haematol.2023.284078

Dexamethasone treatment for COVID-19 is related to increased mortality in hematologic malignancy patients: results from the EPICOVIDEHA Registry (611 Online Views)

Tommaso Francesco Aiello, Jon Salmanton-Garcia, Francesco Marchesi, Barbora Weinbergerova, Andreas Glenthoj, Jens Van Praet, Francesca Farina, Julio Davila-Valls, Sonia Martin-Perez, Shaimaa El-Ashwah, Martin Schonlein, Iker Falces-Romero, Jorge Labrador, Uluhan Sili, Caterina Buquicchio, Antonio Vena, Gaetan Plantefeve, Verena Petzer, Monika M. Biernat, Tobias Lahmer, Ildefonso Espigado, Jaap Van Doesum, Ola Blennow, Klara Piukovics, Carlo Tascini, Michail Samarkos, Yavuz M. Bilgin, Luana Fianchi, Federico Itri, Toni Valković, Nicola S. Fracchiolla, Michelina Dargenio, Moraima Jimenez, Ferenc Magyari, Alberto Lopez-Garcia, Lucia Prezioso, Natasha Čolović, Evgenii Shumilov, Ghaith Abu-Zeinah, Carolin Krekeler, Esperanza Lavilla-Rubira, Mario Virgilio Papa, Tomas Jose Gonzalez-Lopez, Laszlo Imre Pinczes, Fatih Demirkan, Natasha Ali, Caroline Besson, Guillemette Fouquet, Alessandra Romano, Jose-Angel Hernandez-Rivas, Maria Ilaria Del Principe, Avinash Aujayeb, Maria Merelli, Sylvain Lamure, Joyce Marques De Almeida, Maria Gomes Da Silva, Noha Eisa, Joseph Meletiadis, Ikhwan Rinaldi, Olimpia Finizio, Ozren Jaksic, Mario Delia, Summiya Nizamuddin, Monia Marchetti, Marriyam Ijaz, Marina Machado, Rebeca Bailen-Almorox, Martin Čerňan, Nicola Coppola, Eleni Gavriilaki, Chiara Cattaneo, Ana Groh, Zlate Stojanoski, Nurettin Erben, Nicola Pantic, Gustavo-Adolfo Mendez, Roberta Di Blasi, Stef Meers, Cristina De Ramon, Nathan C. Bahr, Ziad Emarah, Gina Varricchio, Milche Cvetanoski, Ramon Garcia-Sanz, Mirjana Mitrovic, Raphael Lievin, Michaela Hanakova, Zdeněk Račil, Maria Vehreschild, Athanasios Tragiannidis, Raquel Nunes Rodrigues, Daniel Garcia-Bordallo, Raul Cordoba, Alba Cabirta, Anna Nordlander, Emanuele Ammatuna, Elena Arellano, Dominik Wolf, Romane Prin, Alessandro Limongelli, Martina Bavastro, Gokce Melis Colak, Stefanie Grafe, Ditte Stampe Hersby, Laman Rahimli, Oliver A. Cornely, Carolina Garcia-Vidal, Livio Pagano; EPICOVIDEHA study group (Collaborative Group)

https://doi.org/10.3324/haematol.2023.284678

Outcomes after chimeric antigen receptor T-cell therapy across large B-cell lymphoma subtypes (139 Online Views)

Christianne Bourlon, Claire Roddie, Tobias Menne, Jane Norman, Maeve O’Reilly, Adam Gibb, Caroline Besley, Sridhar Chaganti, Carlos Gonzalez Arias, Ceri Jones, Abdalla Dikair, Sharon Allen, Frances Seymour, Wendy Osborne, Amrith Mathew, William Townsend, Piers EM Patten, Eleni Thoulouli, Ahmed Abdulgawad, Sanne Lugthart, Robin Sanderson, Amy A Kirkwood, Andrea Kuhnl

https://doi.org/10.3324/haematol.2024.285010

Universal germline genetic testing in patients with hematologic malignancies using DNA isolated from nail clippings (107 Online Views)

Ozge Ceyhan-Birsoy, Elise Fiala, Satshil Rana, Margaret Sheehan, Jennifer Kennedy, Zarina Yelskaya, Vikas Rai, Yirong Li, Ciyu Yang, Donna Wong, Ivelise Rijo, Jacklyn Casanova, Joshua Somar, Nikita Mehta, Hyeonjin Park, Silvana Ostafi, Kanika Arora, Angelika Padunan, Mark D. Ewalt, Umut Aypar, Panieh Terraf, Maksym Misyura, Sofia Haque, Gerald G. Behr, Tamanna Haque, Maria Sulis, Mark B. Geyer, Christopher Forlenza, Meghan C. Thompson, Maria Carlo, Alicia Latham, Ying Liu, Ahmet Zehir, Rose Brannon, Michael Berger, Luis A Diaz Jr, Ahmet Dogan, Marc Ladanyi, Kseniya Petrova-Drus, Khedoudja Nafa, Kenneth Offit, Maria Arcila, Zsofia K. Stadler, Michael F. Walsh, Diana Mandelker

https://doi.org/10.3324/haematol.2024.285055

Mar 28, 2024

Editorials
Article

IELSG38: phase II trial of front-line chlorambucil plus subcutaneous rituximab induction and maintenance in mucosa-associated lymphoid tissue lymphoma (387 Online Views)

Anastasios Stathis, Maria Cristina Pirosa, Lorella Orsucci, Pierre Feugier, Monica Tani, Hervé Ghesquières, Gerardo Musuraca, Francesca Gaia Rossi, Francesco Merli, Romain Guièze, Emmanuel Gyan, Guido Gini, Dario Marino, Remy Gressin, Franck Morschhauser, Federica Cavallo, Francesca Palombi, Annarita Conconi, Benoît Tessoulin, Hervé Tilly, Manuela Zanni, Maria Giuseppina Cabras, Enrico Capochiani, Catello Califano, Melania Celli, Alessandro Pulsoni, Francesco Angrilli, Ubaldo Occhini, René-Olivier Casasnovas, Guillaume Cartron, Liliana Devizzi, Corinne Haioun, Anna Marina Liberati, Roch Houot, Michele Merli, Giuseppe Pietrantuono, Francesca Re, Michele Spina, Francesco Landi, Franco Cavalli, Francesco Bertoni, Davide Rossi, Nicoletta Ielmini, Elena Borgo, Stefano Luminari, Emanuele Zucca, Catherine Thieblemont

https://doi.org/10.3324/haematol.2023.283918

Editorials
Article

A Japanese retrospective study of non-tuberculous mycobacterial infection in children, adolescents, and young adult patients with hematologic-oncologic diseases (587 Online Views)

Yusuke Tsumura, Hideki Muramatsu, Nobuyuki Tetsuka, Takahiro Imaizumi, Kikue Sato, Kento Inoue, Yoshitomo Motomura, Yuko Cho, Daiki Yamashita, Daichi Sajiki, Ryo Maemura, Ayako Yamamori, Masayuki Imaya, Manabu Wakamatsu, Kotaro Narita, Shinsuke Kataoka, Motoharu Hamada, Rieko Taniguchi, Eri Nishikawa, Atsushi Narita, Nobuhiro Nishio, Seiji Kojima, Yoshihiko Hoshino, Yoshiyuki Takahashi

https://doi.org/10.3324/haematol.2023.283636

Articles

Tocilizumab administration in cytokine release syndrome is associated with hypofibrinogenemia after chimeric antigen receptor T-cell therapy for hematologic malignancies (248 Online Views)

Markus Perl, Konstantin Herfeld, Dennis C. Harrer, Matthias Höpting, Marina Schweiger, Ulrich Sterz, Leonard Knödler, Susanne Heimerl, Leo Hansmann, Wolfgang Herr, Hendrik Poeck, Daniel Wolff, Matthias Edinger, Christina Hart, Matthias A. Fante

https://doi.org/10.3324/haematol.2023.284564

Long-term outcomes and renal responses following autologous hematopoietic stem cell transplantation for light chain deposition disease: a retrospective study on behalf of the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation (152 Online Views)

Laurent Garderet, Luuk Gras, Linda Koster, Liesbeth de Wreede, Rovira Montserrat, Laure Vincent, Roland Fenk, Kamaraj Karunanithi, Dries Deeren, Martin Kaufmann, Jürgen Kuball, Hakan Ozdogu, Maria Jesus Pascual Cascon, Jakob Passweg, Adam Rye, Urpu Salmenniemi, John Snowden, Charlotte Toftmann Hansen, Xavier Leleu, Lauris Gastaud, Joanna Drozd Sokolowska, Kavita Raj, Meral Beksac, Stefan Schönland, Patrick Hayden, Donal McLornan

https://doi.org/10.3324/haematol.2023.284520

Gut microbiome alterations at acute myeloid leukemia diagnosis are associated with muscle weakness and anorexia (188 Online Views)

Sarah A. Pötgens, Violaine Havelange, Sophie Lecop, Fuyong Li, Audrey M. Neyrinck, Florence Bindels, Nathalie Neveux, Jean-Baptiste Demoulin, Ine Moors, Tessa Kerre, Johan Maertens, Jens Walter, Hélène Schoemans, Nathalie M. Delzenne, Laure B. Bindels

https://doi.org/10.3324/haematol.2023.284138

MYC overexpression in natural killer cell lymphoma: prognostic and therapeutic implications (190 Online Views)

Chengfeng Bi, Yuhua Huang, Roshia Ali, Fang Wang, Xia Yang, Alyssa Bouska, Lu Xu, Xinbao Hao, Matthew A. Lunning, Wing C. Chan, Javeed Iqbal, Dennis D. Weisenburger, Julie M. Vose, Kai Fu

https://doi.org/10.3324/haematol.2023.283811

Letters to the Editor

Elderly long-term survivors in the Nordic phase II study with first-line maintenance temozolomide for primary central nervous system lymphoma: a 10-year follow-up (138 Online Views)

Elisa Jacobsen Pulczynski, Mikkel Runason Simonsen, Outi Kuittinen, Unn-Merete Fagerli, Martin Erlanson, Øystein Fluge, Sirpa Leppä, Bjørn Østenstad, Alexander Fosså, Mikael Eriksson, Tarec El-Galaly, Hanne Kuitunen, Karin Papworth, Maria Ljungqvist, Martin B. Pedersen, Marjukka Pollari

https://doi.org/10.3324/haematol.2024.285207

Non-myeloma light chain cast nephropathy: a multicenter retrospective study on clinicopathological characteristics (128 Online Views)

Ana Cristina Martins, Jean-Baptiste Gibier, Charles Ronsin, Christine Kandel-Aznar, Anne Moreau, Marion Chapal, Diogo Francisco, Hamza Sakhi, Julie Oniszczuk, Lorraine Gueguen, Anne Grunenwald, Mathilde Devaux, Alexandre Karras, Virginie Royal, Marion Rabant, Viviane Gnemmi, Jérôme Olagne, Jean-Paul Duong Van Huyen, Pierre Isnard

https://doi.org/10.3324/haematol.2024.285031

High annualized bleeding rates in pediatric patients with inherited platelet function disorders (90 Online Views)

Shelly Saini, Song Zhang, Sean Yates, Jessica Garcia, Ruchika Sharma, Joseph Formella, Ravindra Sarode, Ayesha Zia

https://doi.org/10.3324/haematol.2024.284996

Acute myeloid leukemia with mast cell differentiation is characterized by interstitial mast cells, complex karyotype, TP53 alterations and poor prognosis (132 Online Views)

Do Hwan Kim, Sa A. Wang, Wei Wang, Guilin Tang, Shaoying Li, C. Cameron Yin, Pei Lin, Marina Konopleva, M. James You, Roberto N. Miranda, Xiaoqiong Wang, Qing Wei, L. Jeffrey Medeiros, Jie Xu

https://doi.org/10.3324/haematol.2024.284976

Cladribine plus cytarabine plus venetoclax in acute myeloid leukemia relapsed or refractory to venetoclax plus hypomethylating agent (634 Online Views)

Nickolas Steinauer, Kristen McCullough, Aref Al-Kali, Hassan B. Alkhateeb, Kebede H. Begna, Abhishek A. Mangaonkar, Antoine N. Saliba, Mehrdad Torghabeh, Mark R. Litzow, William J. Hogan, Mithun Shah, Mrinal M. Patnaik, Animesh Pardanani, Talha Badar, Hemant Murthy, James Foran, Cecilia Arana Yi, Ayalew Tefferi, Naseema Gangat

https://doi.org/10.3324/haematol.2024.284962

Case Reports

BCMA x CD3 T-cell engager in a patient with penta-refractory multiple myeloma and HIV: a clinical and immunological report (182 Online Views)

Leon Cords, Christoph Schaefers, Abdulaziz Kamili, Christian Hoffmann, Sophia Cichutek, Friedrich Haag, Susanne Polywka, Carsten Bokemeyer, Lisa Leypoldt, Winfried Alsdorf, Julian Schulze zur Wiesch, Katja C. Weisel

https://doi.org/10.3324/haematol.2023.284917

Mar 21, 2024

Editorials
Article

B-cell precursor acute lymphoblastic leukemia elicits an interferon-α/β response in bone marrow-derived mesenchymal stroma (261 Online Views)

Mandy W. E. Smeets, Elisabeth M. P. Steeghs, Jan Orsel, Femke Stalpers, Myrthe M. P. Vermeeren, Christina H. J. Veltman, Lotte Slenders, Stefan Nierkens, Cesca van de Ven, Monique L. den Boer

https://doi.org/10.3324/haematol.2023.283494

Articles

Steroid-free combination of 5-azacytidine and venetoclax for the treatment of multiple myeloma (873 Online Views)

Lyndsey Flanagan, Aisling Coughlan, Nicola Cosgrove, Andrew Roe, Yu Wang, Stephanie Gilmore, Izabela Drozdz, Claire Comerford, Jeremy Ryan, Emma Minihane, Salma Parvin, Michael O’Dwyer, John Quinn, Philip Murphy, Simon Furney, Siobhan Glavey, Tríona Ní Chonghaile; Leukemia Research Foundation, Science Foundation Ireland, Breakthrough Cancer Research (Collaborative Group)

https://doi.org/10.3324/haematol.2023.283771

Letters to the Editor

Systemic diffuse large B-cell lymphoma involving the central nervous system have high rates of defective antigen presentation and immune surveillance (416 Online Views)

Joel Wight, Piers Blombery, Jennifer Lickiss, Melinda Burgess, Clare Gould, Adrian Minson, Fiona Swain, Muhammed B. Sabdia, Maher K. Gandhi, Andrew Birchley, Colm Keane, Eliza A Hawkes

https://doi.org/10.3324/haematol.2023.284600

Mar 14, 2024

Editorials
Article

D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells (492 Online Views)

Kathrin Hammon, Kathrin Renner, Michael Althammer, Florian Voll, Nathalie Babl, Sonja-Maria Decking, Peter J. Siska, Carina Matos, Zugey Elizabeth Cárdenas Conejo, Karina Mendes, Friederike Einwag, Heiko Siegmund, Sabine Iberl, Raffaela S. Berger, Katja Dettmer, Rebecca Schoenmehl, Christoph Brochhausen, Wolfgang Herr, Peter J. Oefner, Michael Rehli, Simone Thomas, Marina Kreutz

https://doi.org/10.3324/haematol.2023.283597

Articles

Imatinib treatment and longitudinal growth in pediatric patients with chronic myeloid leukemia: Influence of demographic, pharmacological, and genetic factors in the German CML-PAED cohort (257 Online Views)

Sophie Stiehler, Stephanie Sembill, Oliver Schleicher, Michaela Marx, Manfred Rauh, Manuela Krumbholz, Axel Karow, Meinolf Suttorp, Joachim Woelfle, Carlo Maj, Markus Metzler

https://doi.org/10.3324/haematol.2023.284668

Stroke without cerebral arteriopathy in sickle cell disease children: causes and treatment (170 Online Views)

Sarah Liane Linguet, Suzanne Verlhac, Florence Missud, Laurent Holvoet-Vermaut, Valentine Brousse, Ghislaine Ithier, Alexandra Ntorkou, Emmanuelle Lesprit, Malika Benkerrou, Manoëlle Kossorotoff, Berengere Koehl

https://doi.org/10.3324/haematol.2023.283773

Letters to the Editor

Bendamustine and rituximab as first-line treatment for symptomatic splenic marginal zone lymphoma: long-term outcome and impact of early unmeasurable minimal residual disease attainment from the BRISMA/IELSG36 phase II study (276 Online Views)

Emilio Iannitto, Simone Ferrero, Côme Bommier, Daniela Drandi, Martina Ferrante, Krimo Bouabdallah, Sylvain Carras, Guido Gini, Vincent Camus, Salvatrice Mancuso, Luigi Marcheselli, Angela Ferrari, Michele Merli, Benoit Tessoulin, Caterina Stelitano, Kheira Beldjord, Giovanni Roti, Fabrice Jardin, Barbara Castagnari, Francesca Palombi, Lucile Baseggio, Alexandra Traverse-Glehen, Claudio Tripodo, Anna Marina Liberati, Margherita Parolini, Sara Usai, Caterina Patti, Massimo Federico, Maurizio Musso, Marco Ladetto, Emanuele Zucca, Catherine Thieblemont

https://doi.org/10.3324/haematol.2023.284109

Low-dose non-steroidal anti-inflammatory drugs: a promising approach for the treatment of symptomatic bone marrow failure in Ghosal hematodiaphyseal dysplasia (235 Online Views)

Jonathan Bordat, Felipe Suarez, Valérie Cormier-Daire, Regis Peffault de Latour, Jean Soulier, Veronique Meignin, Mathilde Doyard, Lise Larcher, Stephane Vanderbecken, Flore Sicre de Fontbrune

https://doi.org/10.3324/haematol.2023.284098

Case Reports

Classical meets malignant hematology: a case of acquired εγδβ-thalassemia in clonal hematopoiesis (175 Online Views)

Armin P. Piehler, Marietta Truger, Jan-Hendrik Kozik, Sandra Weissmann, Martin Schwonzen, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Gregor Hoermann, Claudia Haferlach

https://doi.org/10.3324/haematol.2024.285083

Mar 7, 2024

Editorials

Editorials
Letter to the Editor

Genomic landscape of patients in a phase II study of zanubrutinib in ibrutinib- and/or acalabrutinib-intolerant patients with B-cell malignancies (519 Online Views)

Linlin Xu, Mazyar Shadman, Ian W. Flinn, Moshe Y. Levy, Ryan Porter, John M. Burke, Syed F. Zafar, Jennifer L. Cultrera, Jamal Misleh, Edwin C. Kingsley, Habte A. Yimer, Benjamin Freeman, Arvind Chaudhry, Praveen K. Tumula, Mitul D. Gandhi, Rocco Crescenzo, Kunthel By, Aileen Cohen, Dih-Yih Chen, Adam Idoine, Sudhir Manda, Jeff P. Sharman, Vanitha Ramakrishnan

https://doi.org/10.3324/haematol.2023.283861

Review Articles

Articles

Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies (442 Online Views)

Melissa Krystel-Whittemore, Kseniya Petrova-Drus, Ryan N. Ptashkin, Mark D. Ewalt, JinJuan Yao, Ying Liu, Menglei Zhu, Jamal Benhamida, Benjamin Durham, Jyoti Kumar, Khedoudja Nafa, Iwona Kiecka, Anita S. Bowman, Erika Gedvilaite, Jacklyn Casanova, Yun-Te Lin, Abhinita S. Mohanty, Satshil Rana, Anoop Balakrishnan Rema, Ivelise Rijo, Nelio Chaves, Paulo Salazar, Anita Yun, Sean Lachhander, Wei Wang, Mohammad S. Haque, Wenbin Xiao, Mikhail Roshal, Sergio Giralt, Gilles Salles, Raajit Rampal, Eytan M. Stein, Miguel-Angel Perales, Steven Horwitz, Ann Jakubowski, Doris Ponce, Alina Markova, Ozge Birsoy, Diana Mandelker, Simon Mantha, Ahmet Dogan, Ryma Benayed, Marc Ladanyi, Michael F. Berger, A. Rose Brannon, Ahmet Zehir, Chad Vanderbilt, Maria E. Arcila

https://doi.org/10.3324/haematol.2024.285054

Functional and multi-omics signatures of mitapivat efficacy upon activation of pyruvate kinase in red blood cells from patients with sickle cell disease (364 Online Views)

Angelo D’Alessandro, Kang Le, Maureen Lundt, Quan Li, Emily B. Dunkelberger, Troy Cellmer, Andrew J. Worth, Spurthi Patil, Chris Huston, Abby Grier, Monika Dzieciatkowska, Daniel Stephenson, William A. Eaton, Swee Lay Thein

https://doi.org/10.3324/haematol.2023.284831

Prognostic impact of SF3B1 mutation and multilineage dysplasia in myelodysplastic syndromes with ring sideroblasts: a Mayo Clinic study of 170 informative cases (291 Online Views)

Faiqa Farrukh, Maymona Abdelmagid, Abhishek Mangaonkar, Mrinal Patnaik, Aref Al-Kali, Michelle A. Elliott, Kebede H. Begna, Christopher C. Hook, William J. Hogan, Animesh Pardanani, Mark R. Litzow, Rhett P. Ketterling, Naseema Gangat, Daniel A. Arber, Attilio Orazi, Rong He, Kaaren Reichard, Ayalew Tefferi

https://doi.org/10.3324/haematol.2023.284719

Impact and utility of follicular lymphoma GELF criteria in routine care: an Australasian Lymphoma Alliance study (268 Online Views)

Allison Barraclough, Shivam Agrawal, Dipti Talaulikar, Geoffrey Chong, Edward Yoo, Chan Y. Cheah, Nunzio Franco, Bianca Nguyen, Howard Mutsando, Fatima Tahir, Judith Trotman, Jing Huang, Colm Keane, Mitchel Lincoln, Tara Cochrane, Anna M. Johnston, Michael Dickinson, Stephen Opat, Zoe K. McQuilten, Erica M. Wood, Gayathri St George, Eliza A. Hawkes

https://doi.org/10.3324/haematol.2023.284538

Small extracellular vesicles derived from acute myeloid leukemia cells promote leukemogenesis by transferring miR-221-3p (497 Online Views)

Mengyu Li, Guohuan Sun, Jinlian Zhao, Shuangshuang Pu, Yanling Lv, Yifei Wang, Yapu Li, Xiangnan Zhao, Yajie Wang, Shangda Yang, Tao Cheng, Hui Cheng

https://doi.org/10.3324/haematol.2023.284145

Letters to the Editor

Incidence and outcome of central nervous system relapse after hematopoietic stem cell transplantation in patients suffering from acute myeloid leukemia and acute lymphoblastic leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (233 Online Views)

Sabine Blum, Yves Chalandon, Myriam Labopin, Jürgen Finke, Tobias Gedde-Dahl, Tarek Ben Othman, Jan J. Cornelissen, Pavel Jindra, Hélène Labussière-Wallet, Matthew Collin, Stig Lenhoff, Guido Kobbe, Norma C. Gutiérrez, Arnon Nagler, Mohamad Mohty

https://doi.org/10.3324/haematol.2023.284858

Case Reports

HJV mutations causing hemochromatosis: variable phenotypic expression in a pair of twins (162 Online Views)

Akhila Vadivelan, Sarah Zhang, Daniel N. Srole, Elizabeth A. Marcus, George Carvalho Neto, Elizabeta Nemeth, Tomas Ganz, Satiro De Oliveira

https://doi.org/10.3324/haematol.2023.284134

Perspective Articles

Feb 29, 2024

Review Articles

Spotlight Review

Articles

B-cell precursor acute lymphoblastic leukemia elicits an interferon-α/β response in bone marrow-derived mesenchymal stroma (261 Online Views)

Mandy W. E. Smeets, Elisabeth M. P. Steeghs, Jan Orsel, Femke Stalpers, Myrthe M. P. Vermeeren, Christina H. J. Veltman, Lotte Slenders, Stefan Nierkens, Cesca van de Ven, Monique L. den Boer

https://doi.org/10.3324/haematol.2023.283494

Characterization of zanubrutinib safety and tolerability profile and comparison with ibrutinib safety profile in patients with B-cell malignancies: post-hoc analysis of a large clinical trial safety database (1269 Online Views)

Jennifer R. Brown, Paolo Ghia, Wojciech Jurczak, Brad S. Kahl, Nicole Lamanna, Tadeusz Robak, Mazyar Shadman, Constantine S. Tam, Lugui Qiu, Jason Paik, Tommi Salmi, Liping Wang, Jun Zhang, Meng Zhang, Aileen Cohen, Han Ma, Alessandra Tedeschi

https://doi.org/10.3324/haematol.2023.283846

UBTF tandem duplications in pediatric myelodysplastic syndrome and acute myeloid leukemia: implications for clinical screening and diagnosis (503 Online Views)

Juan M. Barajas, Masayuki Umeda, Lisett Contreras, Mahsa Khanlari, Tamara Westover, Michael P. Walsh, Emily Xiong, Chenchen Yang, Brittney Otero, Marc Arribas-Layton, Sherif Abdelhamed, Guangchun Song, Xiaotu Ma, Melvin E. Thomas 3rd, Jing Ma, Jeffery M. Klco

https://doi.org/10.3324/haematol.2023.284683

Letters to the Editor

Proteogenomic profiling uncovers differential therapeutic vulnerabilities between TCF3::PBX1 and TCF3::HLF translocated B-cell acute lymphoblastic leukemia (398 Online Views)

Lena Blumel, Flavia Bernardi, Daniel Picard, Jacob Torrejon Diaz, Vera H. Jepsen, Rebecca Hasselmann, Julian Schliehe-Diecks, Jasmin Bartl, Nan Qin, Beat Bornhauser, Sanil Bhatia, Blerim Marovka, Veronique Marsaud, Florent Dingli, Damarys Loew, Martin Stanulla, Jean-Pierre Bourqin, Arndt Borkhardt, Marc Remke, Olivier Ayrault, Ute Fischer

https://doi.org/10.3324/haematol.2023.283928

Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia (315 Online Views)

Shannon L. Carey-Smith, Maryam H. Simad, Kunjal Panchal, Carlos Aya-Bonilla, Hannah Smolders, Sang Lin, Jesse D. Armitage, Vivien T. Nguyen, Kathryn Bentley, Jette Ford, Sajla Singh, Joyce Oommen, Anouchka P. Laurent, Thomas Mercher, John D. Crispino, Andrew P. Montgomery, Michael Kassiou, Thierry Besson, Emmanuel Deau, Laurent Meijer, Laurence C. Cheung, Rishi S. Kotecha, Sébastien Malinge

https://doi.org/10.3324/haematol.2023.284271

Mycophenolate mofetil is associated with inferior overall survival in cytomegalovirus seropositive patients with acute myeloid leukemia undergoing hematopoietic cell transplantation (234 Online Views)

Rima M. Saliba, Stephanie J. Lee, Paul A Carpenter, Geoffrey R Hill, Catherine J. Lee, Amin Alousi, May Daher, George Chen, Richard E. Champlin, Katayoun Rezvani, Elizabeth J. Shpall, Rohtesh S. Mehta

https://doi.org/10.3324/haematol.2023.284501

Health-related quality of life in relapsed/refractory multiple myeloma treated with melflufen and dexamethasone: analyses from the phase III OCEAN study (590 Online Views)

Fredrik H. Schjesvold, Heinz Ludwig, Sossana Delimpasi, Pawel Robak, Daniel Coriu, Waldemar Tomczak, Ludek Pour, Ivan Spicka, Meletios-Athanasios Dimopoulos, Tamas Masszi, Natalia G. Chernova, Anna Sandberg, Marcus Thuresson, Stefan Norin, Nicolaas A. Bakker, Maria-Victoria Mateos, Paul G. Richardson, Pieter Sonneveld

https://doi.org/10.3324/haematol.2023.284635

Feb 22, 2024

Editorials
Article

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma (658 Online Views)

Stien De Coninck, Renate De Smedt, Beatrice Lintermans, Lindy Reunes, Hansen J. Kosasih, Alexandra Reekmans, Lauren M. Brown, Nadine Van Roy, Bruno Palhais, Juliette Roels, Malaika Van der Linden, Jo Van Dorpe, Panagiotis Ntziachristos, Frederik W. van Delft, Marc R. Mansour, Tim Pieters, Tim Lammens, Barbara De Moerloose, Charles E. de Bock, Steven Goossens, Pieter Van Vlierberghe

https://doi.org/10.3324/haematol.2023.283981

Articles

Transfusion of ever-pregnant donor red blood cells and mortality of male patients (189 Online Views)

Sarah J. Valk, Camila Caram-Deelder, Rolf. H.H. Groenwold, Dorothea Evers, Karen M.K. de Vooght, Daan van de Kerkhof, Marielle J Wondergem, Nathalie C.V. Péquériaux, Francisca Hudig, Jaap Jan Zwaginga, Rutger A. Middelburg, Johanna G. van der Bom

https://doi.org/10.3324/haematol.2023.283550

Targeting TNF/IL-17/MAPK pathway in hE2A-PBX1 leukemia: effects of OUL35, KJ-Pyr-9, and CID44216842 (393 Online Views)

Haiping Luo, Qiqi Li, Jiaxin Hong, Zhibin Huang, Wenhui Deng, Kunpeng Wei, Siyu Lu, Hailong Wang, Wenqing Zhang, Wei Liu

https://doi.org/10.3324/haematol.2023.283647

Outcome of primary hemophagocytic lymphohistiocytosis: a report on 143 patients from the Italian Registry (285 Online Views)

Francesco Pegoraro, Aurora Chinnici, Linda Beneforti, Michele Tanturli, Irene Trambusti, Carmela De Fusco, Concetta Micalizzi, Veronica Barat, Simone Cesaro, Stefania Gaspari, Fabiola Dell’Acqua, Alessandra Todesco, Fabio Timeus, Maurizio Aricò, Claudio Favre, Annalisa Tondo, Maria Luisa Coniglio, Elena Sieni; AIEOP Histiocytosis Working Group (Collaborative Group)

https://doi.org/10.3324/haematol.2023.283893

IELSG38: phase II trial of front-line chlorambucil plus subcutaneous rituximab induction and maintenance in mucosa-associated lymphoid tissue lymphoma (387 Online Views)

Anastasios Stathis, Maria Cristina Pirosa, Lorella Orsucci, Pierre Feugier, Monica Tani, Hervé Ghesquières, Gerardo Musuraca, Francesca Gaia Rossi, Francesco Merli, Romain Guièze, Emmanuel Gyan, Guido Gini, Dario Marino, Remy Gressin, Franck Morschhauser, Federica Cavallo, Francesca Palombi, Annarita Conconi, Benoît Tessoulin, Hervé Tilly, Manuela Zanni, Maria Giuseppina Cabras, Enrico Capochiani, Catello Califano, Melania Celli, Alessandro Pulsoni, Francesco Angrilli, Ubaldo Occhini, René-Olivier Casasnovas, Guillaume Cartron, Liliana Devizzi, Corinne Haioun, Anna Marina Liberati, Roch Houot, Michele Merli, Giuseppe Pietrantuono, Francesca Re, Michele Spina, Francesco Landi, Franco Cavalli, Francesco Bertoni, Davide Rossi, Nicoletta Ielmini, Elena Borgo, Stefano Luminari, Emanuele Zucca, Catherine Thieblemont

https://doi.org/10.3324/haematol.2023.283918

A predictive classifier of poor prognosis in transplanted patients with juvenile myelomonocytic leukemia: a study on behalf of the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire (296 Online Views)

Déborah Meyran, Chloé Arfeuille, Sylvie Chevret, Quentin Neven, Aurélie Caye-Eude, Elodie Lainey, Arnaud Petit, Fanny Rialland, Gérard Michel, Dominique Plantaz, Charlotte Jubert, Alexandre Theron, Virginie Gandemer, Marie Ouachée-Chardin, Catherine Paillard, Bénédicte Bruno, Nimrod Buchbinder, Cécile Pochon, Charlotte Calvo, Mony Fahd, André Baruchel, Hélène Cavé, Jean-Hugues Dalle, Marion Strullu

https://doi.org/10.3324/haematol.2023.284103

Enhancement of PRMT6 binding to a novel germline GATA1 mutation associated with congenital anemia (322 Online Views)

Yingsi Lu, Qingqing Zhu, Yun Wang, Meiling Luo, Junbin Huang, Qian Liang, Lifen Huang, Jing Ouyang, Chenxin Li, Nannan Tang, Yan Li, Tingting Kang, Yujia Song, Xiaoyu Xu, Liping Ye, Guoxing Zheng, Chun Chen, Chengming Zhu

https://doi.org/10.3324/haematol.2023.284183

Selective pharmacologic targeting of CTPS1 shows single-agent activity and synergizes with BCL2 inhibition in aggressive mantle cell lymphoma (252 Online Views)

Romane Durand, Céline Bellanger, Charlotte Kervoëlen, Benoit Tessoulin, Christelle Dousset, Emmanuelle Menoret, Hélène Asnagli, Andrew Parker, Philip Beer, Catherine Pellat-Deceunynck, David Chiron

https://doi.org/10.3324/haematol.2023.284345

A NOTCH3-CXCL12-driven myeloma-tumor niche signaling axis promotes chemoresistance in multiple myeloma (500 Online Views)

Hayley M. Sabol, Cody Ashby, Manish Adhikari, Aric Anloague, Japneet Kaur, Sharmin Khan, Samrat Roy Choudhury, Carolina Schinke, Michela Palmieri, C. Lowry Barnes, Elena Ambrogini, Intawat Nookaew, Jesus Delgado-Calle

https://doi.org/10.3324/haematol.2023.284443

Genomic profiling of pediatric hematologic malignancies and diagnosis of cancer predisposition syndromes: tumor-only versus paired tumor-normal sequencing (206 Online Views)

Haley Newman, Mary Egan Clark, Derek Wong, Jinhua Wu, Garrett M Brodeur, Stephen P Hunger, Sarah K Tasian, Timothy Olson, Julia T. Warren, David T Teachey, Kira Bona, Jeffrey Schubert, Netta Golenberg, Maha Patel, Elizabeth H Denenberg, Elizabeth A Fanning, Jiani Chen, Tamara Luke, Sarah Charles, Daniel Gallo, Kajia Cao, Weixuan Fu, Zhiqian Fan, Lea F Surrey, Gerald Wertheim, Minjie Luo, Suzanne P MacFarland, Marilyn M Li, Yiming Zhong

https://doi.org/10.3324/haematol.2023.284855

Letters to the Editor

Pubertal development of transfusion-dependent thalassemia patients in the era of oral chelation with deferasirox: results from the French registry (191 Online Views)

Mathilde Veneziano Broccia, Julia Vergier, Audrey Benoit, Yoann Huguenin, Anne Lambilliotte, Marie Pierre Castex, Stephanie Gourdon, Ghislaine Ithier, Kamila Kebaili, Pierre Rohrlich, Corinne Pondarre, Abdourahim Chamouine, Pauline Simon, Kokou Placide Agbo Kpati, Slimane Allali, Sandrine Baron-Joly, Sophie Bayart, Nicolas Billaud, Valentine Brousse, Cecile Dumesnil, Nathalie Garnier, Isabelle Guichard, Laure Joseph, Annie Kamdem, Julie Maitre, Catherine Mathey, Catherine Paillard, Aurelie Phulpin, Cecile Renard, Cecile Stoven, Mohamed Touati, Capucine Trochu, Suzanne Mathieu Nafissi, Catherine Badens, Sarah Szepetowski, Isabelle Thuret

https://doi.org/10.3324/haematol.2023.283610

TENT5C/FAM46C modulation in vivo reveals a trade-off between antibody secretion and tumor growth in multiple myeloma (291 Online Views)

Massimo Resnati, Sara Pennacchio, Lisa Viviani, Tommaso Perini, Maria Materozzi, Ugo Orfanelli, Jessica Bordini, Raffaella Molteni, Mario Nuvolone, Matteo Da Vià, Francesca Lazzaroni, Niccolò Bolli, Simone Cenci, Enrico Milan

https://doi.org/10.3324/haematol.2023.284299

Randomized phase III GnG study on two schedules of gemtuzumab ozogamicin as adjunct to intensive induction therapy and double-blinded intensive post-remission therapy with or without glasdegib in patients with newly diagnosed acute myeloid leukemia (268 Online Views)

Sonia Jaramillo, Johannes Krisam, Lucian Le Cornet, Markus Kratzmann, Lukas Baumann, Olga Eissymont, Martina Crysandt, Martin Görner, Sabine Kayser, Stefan Krause, Christoph Schliemann, Tobias Gaska, Martin Kaufmann, Jens Chemnitz, Markus Schaich, Alexander Hoellein, Uwe Platzbecker, Meinhard Kieser, Carsten Müller-Tidow, Richard F. Schlenk

https://doi.org/10.3324/haematol.2023.284346

Belantamab mafodotin: an important treatment option for vulnerable patients with triple class exposed relapsed and/or refractory multiple myeloma (358 Online Views)

Maria Victoria Mateos, Katja Weisel, Evangelos Terpos, Sossana Delimpasi, Efstathios Kastritis, Elena Zamagni, Michel Delforge, Enrique Ocio, Eirini Katodritou, Francesca Gay, Alessandra Larocca, Xavier Leleu, Paula Rodriguez Otero, Fredik Schjesvold, Michele Cavo, Meletios A. Dimopoulos

https://doi.org/10.3324/haematol.2023.284694

TP53 DNA binding domain mutational status and rituximab-based treatment are independent prognostic factors for pediatric Burkitt lymphoma patients stratification (244 Online Views)

Gaia Martire, Federica Lovisa, Elisa Carraro, Domenico Rizzato, Simone Cesaro, Rosa Maria Mura, Annalisa Tondo, Cinzia Bertolin, Francesca Boaretto, Leonardo Salviati, Alessandra Biffi, Marta Pillon, Lara Mussolin

https://doi.org/10.3324/haematol.2023.284868

Case Reports

Phenomenon of tumor flare with talquetamab in a patient with extramedullary myeloma (275 Online Views)

Mark Forsberg, Santiago Beltran, Mendel Goldfinger, Murali Janakiram, Deepak Kalbi, Amit Verma, Dennis Cooper, Nishi Shah

https://doi.org/10.3324/haematol.2023.284436

Treatment of immune-mediated thrombotic thrombocytopenic purpura without plasma exchange (255 Online Views)

Marco Capecchi, Giada Gazzola, Pasquale Agosti, Pasqualina De Leo, Ilaria Mancini, Barbara Ferrari, Juri Alessandro Giannotta, Andrea Artoni, Flora Peyvandi

https://doi.org/10.3324/haematol.2023.284438

Feb 15, 2024

Editorials
Article

Matching-adjusted indirect comparison from the Lymphoma Epidemiology of Outcomes Consortium for Real World Evidence (LEO CReWE) study to a clinical trial of mosunetuzumab in relapsed or refractory follicular lymphoma (823 Online Views)

Matthew J. Maurer, Carla Casulo, Melissa C. Larson, Thomas M. Habermann, Izidore S. Lossos, Yucai Wang, Loretta J. Nastoupil, Christopher Strouse, Dai Chihara, Peter Martin, Jonathon B. Cohen, Brad S. Kahl, W Richard Burack, Jean L. Koff, Yong Mun, Anthony Masaquel, Mei Wu, Michael C. Wei, Ashwini Shewade, Jia Li, James R. Cerhan, Brian K. Link, Christopher R. Flowers

https://doi.org/10.3324/haematol.2023.283737

Editorials
Article

Histone deacetylase inhibition sensitizes p53-deficient B-cell precursor acute lymphoblastic leukemia to chemotherapy (525 Online Views)

Willem P.J. Cox, Nils Evander, Dorette S. van Ingen Schenau, Gawin R. Stoll, Nadia Anderson, Lieke de Groot, Kari J.T. Grünewald, Rico Hagelaar, Miriam Butler, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

https://doi.org/10.3324/haematol.2023.284101

Review Articles

Spotlight Review

Articles

Selinexor, daratumumab, bortezomib and dexamethasone for the treatment of patients with relapsed or refractory multiple myeloma: results of the phase II, non-randomized, multicenter GEM-SELIBORDARA study (916 Online Views)

Verónica González-Calle, Paula Rodríguez-Otero, Anna Sureda, Felipe de Arriba, Marta Reinoso, Paz Ribas, Ana Pilar González-Rodríguez, Yolanda González, Albert Oriol, Joaquín Martínez-López, Marta Sonia González, Miguel T. Hernández, Maialen Sirvent, Teresa Cedena, Noemí Puig, Bruno Paiva, Joan Bladé, Juan José Lahuerta, Jesús F. San-Miguel, María-Victoria Mateos

https://doi.org/10.3324/haematol.2023.284089

ETV6::ACSL6 translocation-driven super-enhancer activation leads to eosinophilia in acute lymphoblastic leukemia through IL-3 overexpression (492 Online Views)

Wenqian Xu, Feng Tian, Xiaolu Tai, Gaoxian Song, Yuanfang Liu, Liquan Fan, Xiangqin Weng, Eunjeong Yang, Meng Wang, Martin Bornhäuser, Chao Zhang, Richard B. Lock, Jason W.H. Wong, Jin Wang, Duohui Jing, Jian-Qing Mi

https://doi.org/10.3324/haematol.2023.284121

Belantamab mafodotin, lenalidomide and dexamethasone in transplant-ineligible patients with newly diagnosed multiple myeloma: Part 1 results of a phase I/II study (469 Online Views)

Evangelos Terpos, Maria Gavriatopoulou, Ioannis Ntanasis-Stathopoulos, Panagiotis Malandrakis, Despina Fotiou, Magdalini Migkou, Foteini Theodorakakou, Vasiliki Spiliopoulou, Ioannis V Kostopoulos, Rodanthi-Eleni Syrigou, Evangelos Eleutherakis-Papaiakovou, Stavros Gkolfinopoulos, Ourania E Tsitsilonis, Efstathios Kastritis, Meletios A. Dimopoulos

https://doi.org/10.3324/haematol.2023.284347

Effects of allopurinol on 6-mercaptopurine metabolism in unselected patients with pediatric acute lymphoblastic leukemia: a prospective phase II study (334 Online Views)

Jonatan Källström, Riita Niinimäki, Johan Fredlund, Hartmut Vogt, Laura Korhonen, Anders Castor, Josefine Palle, Arja Harila, Magnus Borssén, Jonas Abrahamsson, Torben Ek

https://doi.org/10.3324/haematol.2023.284390

Letters to the Editor

Guidelines

Approaches for bridging therapy prior to chimeric antigen receptor T cells for relapsed/refractory acute lymphoblastic B-lineage leukaemia in children and young adults (459 Online Views)

Tobias Feuchtinger, Peter Bader, Marion Subklewe, Maike Breidenbach, Semjon Willier, Markus Metzler, Nicola Gökbuget, Julia Hauer, Fabian Müller, Paul-Gerhardt Schlegel, Michael Frühwald, Christoph Schmid, Anja Troeger, Claudia Baldus, Roland Meisel, Annette Künkele, Max Topp, Jean-Pierre Bourquin, Gunnar Cario, Arend von Stackelberg, Christina Peters

https://doi.org/10.3324/haematol.2023.283780

Feb 8, 2024

Editorials
Case Report

Cerebral venous sinus thrombosis and thrombocytopenia due to heparin-independent anti-PF4 antibodies after adenovirus infection (842 Online Views)

Günalp Uzun, Jan Zlamal, Karina Althaus, Andrea Bevot, Florian Hennersdorf, Nina Wolska, Anna Jock, Jan Kern, Vanya Icheva, Sven Poli, Ulrike Ernemann, Andreas Neu, Tamam Bakchoul

https://doi.org/10.3324/haematol.2023.284127

Editorials

Editorials
Article

Genetic landscape and clinical outcomes of patients with BCOR mutated myeloid neoplasms (589 Online Views)

Anmol Baranwal, Mark Gurney, Rami Basmaci, Bahga Katamesh, Rong He, David S. Viswanatha, Patricia Greipp, James Foran, Talha Badar, Hemant Murthy, Cecilia Arana Yi, Jeanne Palmer, Abhishek A. Mangaonkar, Mrinal M. Patnaik, Mark R. Litzow, William J. Hogan, Kebede Begna, Naseema Gangat, Ayalew Tefferi, Aref Al-Kali, Mithun V. Shah, Hassan B. Alkhateeb

https://doi.org/10.3324/haematol.2023.284185

Review Articles

Articles

Letters to the Editor

Targeting CCR4 with mogamulizumab in refractory CD3-CD4+ lymphocytic-variant hypereosinophilic syndrome (244 Online Views)

Emmanuel Ledoult, Matthieu Groh, Bertrand Meresse, Romain Dubois, Jacques Trauet, Elise Toussaint, Marie Delbeke, Eric Hachulla, Louis Terriou, Adèle De Masson, Michele Vasseur, Myriam Labalette, David Launay, Jean-Emmanuel Kahn, Guillaume Lefevre

https://doi.org/10.3324/haematol.2023.284429

Role of red cell mass evaluation in myeloproliferative neoplasms with splanchnic vein thrombosis and normal hemoglobin value: a study of the France Intergroupe des Syndromes myeloprolifératifs (268 Online Views)

Jean Galtier, Louis Drevon, Yannick Le Bris, Stephane Giraudier, Mathieu Wemeau, Laurence Legros, Damien Luque Paz, François Girodon, Jean-Jacques Kiladjian, Charles Mesguich, Marie Parrens, Clémence Mediavilla, Lydia Roy, Alexandre Guy, Olivier Mansier, Jean-Christophe Ianotto, Chloe James

https://doi.org/10.3324/haematol.2023.284488

A phase II randomized, placebo-controlled, multicenter trial to evaluate the efficacy of cytomegalovirus PepVax vaccine in preventing cytomegalovirus reactivation and disease after allogeneic hematopoietic stem cell transplant (355 Online Views)

Ryotaro Nakamura, Corinna La Rosa, Dongyun Yang, Joshua A. Hill, Armin Rashidi, Hannah Choe, Qiao Zhou, Chetan Raj Lingaraju, Teodora Kaltcheva, Jeffrey Longmate, Jennifer Drake, Cynthia Slape, Lupe Duarte, Monzr M. Al Malki, Vinod A. Pullarkat, Ahmed Aribi, Steven Devine, Michael R. Verneris, Jeffrey S. Miller, Stephen J. Forman, Ibrahim Aldoss, Don J. Diamond

https://doi.org/10.3324/haematol.2023.284544

Feb 1, 2024

Editorials
Letter to the Editor

Home time among older adults with acute myeloid leukemia by therapy intensity (312 Online Views)

Christopher E. Jensen, Allison M. Deal, Alexis C. Wardell, Hillary M. Heiling, Konan E. Beke, Daniel R. Richardson

https://doi.org/10.3324/haematol.2023.284133

Articles

Patterns of lower risk myelodysplastic syndrome progression: factors predicting progression to high-risk myelodysplastic syndrome and acute myeloid leukemia (631 Online Views)

Akriti G. Jain, Somedeb Ball, Luis Aguirre, Najla Al Ali, David Kaldas, Sara Tinsley-Vance, Andrew Kuykendall, Onyee Chan, Kendra Sweet, Jeffrey E. Lancet, Eric Padron, David A. Sallman, Rami Komrokji

https://doi.org/10.3324/haematol.2023.283661

CD74 is expressed in a subset of pediatric acute myeloid leukemia patients and is a promising target for therapy: a report from the Children’s Oncology Group (387 Online Views)

Andrew J. Menssen, Chad A. Hudson, Todd Alonzo, Robert Gerbing, Laura Pardo, Amanda Leonti, Jacqueline A. Cook, Fan-Chi Hsu, Loren L. Lott, Fangyan Dai, Collette Fearing, Keely Ghirardelli, Tiffany Hylkema, Katherine Tarlock, Keith R. Loeb, Edward A. Kolb, Todd Cooper, Jessica Pollard, Denise A. Wells, Michael R. Loken, Richard Aplenc, Soheil Meshinchi, Lisa Eidenschink Brodersen

https://doi.org/10.3324/haematol.2023.283757

Genetic landscape and clinical outcomes of patients with BCOR mutated myeloid neoplasms (589 Online Views)

Anmol Baranwal, Mark Gurney, Rami Basmaci, Bahga Katamesh, Rong He, David S. Viswanatha, Patricia Greipp, James Foran, Talha Badar, Hemant Murthy, Cecilia Arana Yi, Jeanne Palmer, Abhishek A. Mangaonkar, Mrinal M. Patnaik, Mark R. Litzow, William J. Hogan, Kebede Begna, Naseema Gangat, Ayalew Tefferi, Aref Al-Kali, Mithun V. Shah, Hassan B. Alkhateeb

https://doi.org/10.3324/haematol.2023.284185

Isatuximab-pomalidomide-dexamethasone versus pomalidomide-dexamethasone in patients with relapsed and refractory multiple myeloma: final overall survival analysis (1240 Online Views)

Paul G. Richardson, Aurore Perrot, Jesus San Miguel, Meral Beksac, Ivan Spicka, Xavier Leleu, Fredrik Schjesvold, Philippe Moreau, Meletios A. Dimopoulos, Shang-Yi Huang, Jiri Minarik, Michele Cavo, H. Miles Prince, Sandrine Macé, Rick Zhang, Franck Dubin, Mony Chenda Morisse, Kenneth C. Anderson

https://doi.org/10.3324/haematol.2023.284325

Letters to the Editor

A retrospective analysis of gene fusions and treatment outcomes in pediatric acute megakaryoblastic leukemia without Down syndrome (219 Online Views)

Kyogo Suzuki, Asahito Hama, Yusuke Okuno, Yinyan Xu, Atsushi Narita, Nao Yoshida, Hideki Muramatsu, Nobuhiro Nishio, Koji Kato, Seiji Kojima, Keon Hee Yoo, Yoshiyuki Takahashi

https://doi.org/10.3324/haematol.2023.283760

Update and European consensus on a patient-centered core outcome set for multiple myeloma in clinical practice and research (308 Online Views)

Simone Oerlemans, Belle H. de Rooij, Christine Bennink, Lars Bullinger, Annemiek Broijl, Mattia D’Agostino, Edward Laane, Maria Teresa Lupo-Stanghellini, Aurore Perrot, Ruth Wester, Viorica Cursaru, Hans Scheurer, Jan Vesseur, Mehul Dalal, Rohini Sen, Tanja Stamm, Heinz Ludwig, Pieter Sonneveld

https://doi.org/10.3324/haematol.2023.284282

The outcome and predictive model of allogeneic hematopoietic stem cell transplantation among elderly patients with severe aplastic anemia from the Chinese Blood and Marrow Transplant Registry Group (567 Online Views)

Zheng-Li Xu, Lan-Ping Xu, Yi-Cheng Zhang, Yu-Hong Zhou, Er-Lie Jiang, Jian-Ping Zhang, Bin Fu, Gui-Fang Ouyang, Xian-Min Song, Xue-Jun Zhang, Yu-Jun Dong, Nai-Nong Li, Ling Wang, Xi Zhang, Peng-Cheng He, Fan-Sheng Kong, Hui-Xia Liu, Li Liu, Lin Liu, Tai-Wu Xiao, Wen-Wei Xu, Xiao-Jun Xu, Guo-Lin Yuan, Hai Yi, Dan Yu, Li Yu, Xiao-Jun Huang

https://doi.org/10.3324/haematol.2023.284581

Jan 25, 2024

Editorials

Articles

Harnessing the cytotoxic granule exocytosis to augment the efficacy of T-cell-engaging bispecific antibody therapy (478 Online Views)

Mika Casey, Carol Lee, Sharon M. Hoyte, Rebecca L. Johnston, Wing Yu Kwok, Soi Cheng Law, Maher K Gandhi, Simon J Harrison, Kyohei Nakamura

https://doi.org/10.3324/haematol.2023.284435

Letters to the Editor

Hepatosplenic T-cell lymphoma displays an original oyster-shell cytological pattern and a distinct genomic profile from that of gamma-delta T-cell large granular lymphocytic leukemia (302 Online Views)

Anne Desmares, Simon Bouzy, Florian Thonier, Julien Goustille, Francisco Llamas-Gutierrez, Franck Genevieve, Laurane Cottin, Lucile Baseggio, Pierre Lemaire, Carinne Lecoq Lafon, Pascale Cornillet-Lefebvre, Anne-Cécile Galoisy, Chantal Brouzes, Emmanuelle Rault, Elodie Dindinaud, Carole Fleury, Florence Blanc-Jouvan, Soraya Wuilleme, Valérie Bardet, Thierry Fest, Thierry Lamy, Mikael Roussel, Mélanie Pannetier, Cédric Pastoret

https://doi.org/10.3324/haematol.2023.283856

Genomic landscape of patients in a phase II study of zanubrutinib in ibrutinib- and/or acalabrutinib-intolerant patients with B-cell malignancies (519 Online Views)

Linlin Xu, Mazyar Shadman, Ian W. Flinn, Moshe Y. Levy, Ryan Porter, John M. Burke, Syed F. Zafar, Jennifer L. Cultrera, Jamal Misleh, Edwin C. Kingsley, Habte A. Yimer, Benjamin Freeman, Arvind Chaudhry, Praveen K. Tumula, Mitul D. Gandhi, Rocco Crescenzo, Kunthel By, Aileen Cohen, Dih-Yih Chen, Adam Idoine, Sudhir Manda, Jeff P. Sharman, Vanitha Ramakrishnan

https://doi.org/10.3324/haematol.2023.283861

Longitudinal dynamics and clinically available predictors of poor response to COVID-19 vaccination in multiple myeloma (241 Online Views)

Gaurav Agarwal, Sally Moore, Ross Sadler, Sherin Varghese, Alison Turner, Lucia Y Chen, Jemma Larham, Nathanael Gray, Oluremi Carty, Joe Barrett, Constantinos Koshiaris, Jaimal Kothari, Stella Bowcock, Udo Oppermann, Vicky Gamble, Gordon Cook, Chara Kyriakou, Mark Drayson, Supratik Basu, Sarah McDonald, Shelagh McKinley, Sarah Gooding, Muhammad K Javaid, Karthik Ramasamy

https://doi.org/10.3324/haematol.2023.284286

A randomized, double-blind study of zinpentraxin alfa in patients with myelofibrosis who were previously treated with or ineligible for ruxolitinib: Stage 2 of a phase II trial (401 Online Views)

Srdan Verstovsek, Moshe Talpaz, Martha Wadleigh, Alessandro Isidori, Peter te Boekhorst, Michael R. Savona, Prithviraj Bose, Olga Pozdnyakova, Ruben Mesa, Tarec C. El-Galaly, Jennifer O’Sullivan, Katia Gamel, Brian Higgins, Sudhakar Katakam, Boyan Todorov, Kerstin Trunzer, Claire N. Harrison

https://doi.org/10.3324/haematol.2023.284410

Case Reports

Jan 18, 2024

Editorials
Article

CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia (1026 Online Views)

Bruno A. Cardoso, Mafalda Duque, Ana Gírio, Rita Fragoso, Mariana L. Oliveira, James R. Allen, Leila R. Martins, Nádia C. Correia, André Bortolini Silveira, Alexandra Veloso, Shunsuke Kimura, Lisa Demoen, Filip Matthijssens, Sima Jeha, Cheng Cheng, Ching-Hon Pui, Ana R. Grosso, João L. Neto, Sérgio F. de Almeida, Pieter Van Vlieberghe, Charles G. Mullighan, J. Andres Yunes, David M. Langenau, Françoise Pflumio, João T. Barata

https://doi.org/10.3324/haematol.2023.282854

Articles

Phase I study of the Syk inhibitor sovleplenib in relapsed or refractory mature B-cell tumors (456 Online Views)

Yuqin Song, Junning Cao, Qingyuan Zhang, Caixia Li, Lugui Qiu, Junyuan Qi, Huilai Zhang, Wenyu Li, Lihong Liu, Hongmei Jing, Keshu Zhou, Weijing Zhang, Liling Zhang, Daqi Li, Liqun Zou, Haiyan Yang, Wenbin Qian, Hui Zhou, Jianda Hu, Hongyan Yin, Sisi Fu, Songhua Fan, Qian Xu, Jian Wang, Xiaoyun Jia, Guangxiu Dai, Weiguo Su, Jun Zhu

https://doi.org/10.3324/haematol.2022.282401

D-2-hydroxyglutarate supports a tolerogenic phenotype with lowered major histocompatibility class II expression in non-malignant dendritic cells and acute myeloid leukemia cells (492 Online Views)

Kathrin Hammon, Kathrin Renner, Michael Althammer, Florian Voll, Nathalie Babl, Sonja-Maria Decking, Peter J. Siska, Carina Matos, Zugey Elizabeth Cárdenas Conejo, Karina Mendes, Friederike Einwag, Heiko Siegmund, Sabine Iberl, Raffaela S. Berger, Katja Dettmer, Rebecca Schoenmehl, Christoph Brochhausen, Wolfgang Herr, Peter J. Oefner, Michael Rehli, Simone Thomas, Marina Kreutz

https://doi.org/10.3324/haematol.2023.283597

Pediatric-inspired regimen for adolescent and adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia: a prospective study from China (653 Online Views)

Xiaoyuan Gong, Qiuyun Fang, Runxia Gu, Shaowei Qiu, Kaiqi Liu, Dong Lin, Chunlin Zhou, Guangji Zhang, Benfa Gong, Yuntao Liu, Yan Li, Bingcheng Liu, Ying Wang, Hui Wei, Yingchang Mi, Jianxiang Wang

https://doi.org/10.3324/haematol.2023.284228

Carfilzomib, thalidomide, and dexamethasone is safe and effective in relapsed and/or refractory multiple myeloma: final report of the single arm, multicenter phase II ALLG MM018/AMN002 study. (490 Online Views)

Slavisa Ninkovic, Simon J Harrison, Je-Jung Lee, Nick Murphy, Jae Hoon Lee, Jane Estell, Vivien M Chen, Noemi Horvath, Kihuyn Kim, Richard Eek, Bradley Augustson, Soo-Mee Bang, Shang-Yi Huang, Rajeev Rajagopal, Ferenc Szabo, Daniel Engeler, Belinda E Butcher, Peter Mollee, Brian Durie, Wee Joo Chng, Hang Quach

https://doi.org/10.3324/haematol.2023.284238

Autologous stem cell transplant in fit patients with refractory or early relapsed diffuse large B-cell lymphoma that responded to salvage chemotherapy (772 Online Views)

Aung M. Tun, Yucai Wang, Seth Maliske, Ivana Micallef, David J. Inwards, Thomas M. Habermann, Luis Porrata, Jonas Paludo, Jose Villasboas Bisneto, Allison Rosenthal, Mohamed A Kharfan-Dabaja, Stephen M. Ansell, Grzegorz S. Nowakowski, Umar Farooq, Patrick B. Johnston

https://doi.org/10.3324/haematol.2023.284704

Letters to the Editor

MAF translocation remains a strong prognostic factor despite concurrent chromosomal abnormalities (747 Online Views)

Yuntong Liu, Rui Lv, Wenqiang Yan, Jingyu Xu, Huishou Fan, Lingna Li, Jian Cui, Chenxing Du, Shuhui Deng, Weiwei Sui, Dehui Zou, Yan Xu, Lugui Qiu, Gang An

https://doi.org/10.3324/haematol.2023.284666

Jan 11, 2024

Articles

Longitudinal, natural history study reveals the disease burden of idiopathic multicentric Castleman disease (610 Online Views)

Mateo Sarmiento Bustamante, Sheila K. Pierson, Yue Ren, Adam Bagg, Joshua D. Brandstadter, Gordan Srkalovic, Natalie Mango, Daisy Alapat, Mary Jo Lechowicz, Hongzhe Li, Frits van Rhee, Megan S. Lim, David C. Fajgenbaum

https://doi.org/10.3324/haematol.2023.283603

Elucidation of molecular basis of osteolytic bone lesions in advanced multiple myeloma (494 Online Views)

Dongyeop Shin, Myung-Jin Kim, Soyeon Chun, Dongchan Kim, Chansu Lee, Kwang-Sung Ahn, Eunyoung Jung, Dayeon Kim, Byung-Chul Lee, Daehee Hwang, Yonghwan Kim, Sung-Soo Yoon

https://doi.org/10.3324/haematol.2023.283784

Prior cancer and risk of monoclonal gammopathy of undetermined significance: a population-based study in Iceland and Sweden (467 Online Views)

Sæmundur Rögnvaldsson, Sigrun Thorsteinsdóttir, Elisavet Syriopoulou, Ingigerdur Sverrisdottir, Ingemar Turesson, Elias Eythorsson, Jon Thorir Oskarsson, Thorir Einarsson Long, Brynjar Vidarsson, Pall Torfi Onundarson, Bjarni A. Agnarsson, Margret Sigurdardottir, Isleifur Olafsson, Ingunn Thorsteinsdottir, Thor Aspelund, Gauti Kjartan Gislason, Andri Olafsson, Jon Kristinn Sigurdsson, Malin Hultcrantz, Brian G. M. Durie, Stephen Harding, Magnus Bjorkholm, Ola Landgren, Thorvardur Jon Love, Sigurdur Yngvi Kristinsson

https://doi.org/10.3324/haematol.2023.284365

Letters to the Editor

The role of the mineralocorticoid receptor in steroid-induced cytotoxicity in pediatric acute lymphoblastic leukemia (263 Online Views)

Annelienke M. van Hulst, Jordy C.G. van der Zwet, Jessica G.C.A.M. Buijs-Gladdines, Willem K. Smits, Marta Fiocco, Rob Pieters, Frank N. van Leeuwen, Marry M. van den Heuvel-Eibrink, Erica L.T. van den Akker, Jules P.P. Meijerink

https://doi.org/10.3324/haematol.2023.282928

Limited utility of Mayo 2012 cardiac staging system for risk stratification of patients with advanced cardiac AL amyloidosis - analysis of a uniformly treated cohort of 1,275 patients (381 Online Views)

Jahanzaib Khwaja, Sriram Ravichandran, Joshua Bomsztyk, Oliver Cohen, Darren Foard, Ana Martinez-Naharro, Lucia Venneri, Marianna Fontana, Philip N Hawkins, Julian Gillmore, Helen J Lachmann, Shameem Mahmood, Carol Whelan, Amy A Kirkwood, Ashutosh Wechalekar

https://doi.org/10.3324/haematol.2023.284348

Rituximab plus cyclophosphamide and dexamethasone versus bortezomib plus cyclophosphamide and dexamethasone in newly diagnosed symptomatic Waldenström macroglobulinemia: a randomized controlled trial (864 Online Views)

Wenjie Xiong, Rui Lyu, Ying Yu, Tingyu Wang, Yuting Yan, Yi Wang, Wei Liu, Gang An, Shuhui Deng, Yan Xu, Weiwei Sui, Wenyang Huang, Dehui Zou, Jianxiang Wang, Lugui Qiu, Shuhua Yi

https://doi.org/10.3324/haematol.2023.284588

Autologous hematopoietic cell transplantation for T-cell prolymphocytic leukemia: a retrospective study on behalf of the Chronic Malignancies Working Party of the EBMT (322 Online Views)

Joanna Drozd-Sokolowska, Luuk Gras, Linda Koster, Rodrigo Martino, María Queralt Salas, Urpu Salmenniemi, Teresa Zudaire, Lucrecia Yañez, Mar Bellido, Matthew Collin, Martin Kaufmann, Piotr Kozlowski, Xavier Poiré, Christelle Ferra, Antònia Sampol, Keith M. O. Wilson, Anne Cairoli, Tobias Gedde-Dahl, Eric Deconinck, Milena Mirabile, Felipe Suarez, Kavita Raj, Michel van Gelder, Ibrahim Yakoub-Agha, Olivier Tournilhac, Donal P. McLornan

https://doi.org/10.3324/haematol.2023.284359

Jan 4, 2024

Articles

Matched unrelated donor transplantation versus haploidentical transplantation with post-transplant cyclophosphamide in children with acute myeloid leukemia: a PDWP-EBMT study (744 Online Views)

Annalisa Ruggeri, Nicole Santoro, Jacques-Emmanuel Galimard, Krzysztof Kalwak, Mattia Algeri, Ludmila Zubarovskaya, Krzysztof Czyzewski, Elena Skorobogatova, Petr Sedlacek, Caroline Besley, Adriana Balduzzi, Yves Bertrand, Julia Peristeri, Franca Fagioli, Mariane Ifversen, Jolanta Gozdzik, Christina Peters, Birgitta Versluijs, Alessandra Biffi, Arcangelo Prete, Maura Faraci, Ibrahim Ghemlas, Ivana Bodova, Olga Aleinikova, Arnaud Dalissier, Vanderson Rocha, Selim Corbacioglu

https://doi.org/10.3324/haematol.2023.284445

Inotuzumab ozogamicin combined with chemotherapy in pediatric B-cell precursor CD22+ acute lymphoblastic leukemia: results of the phase IB ITCC-059 trial (744 Online Views)

Edoardo Pennesi, Erica Brivio, Anneke C. J. Ammerlaan, Yilin Jiang, Vincent H. J. van der Velden, H. Berna Beverloo, Barbara Sleight, Franco Locatelli, Benoit Brethon, Claudia Rossig, Gernot Engstler, Anna Nilsson, Benedicte Bruno, Arnaud Petit, Bella Bielorai, Carmelo Rizzari, Fanny Rialland, Alba Rubio-San-Simón, Francisco J. Bautista Sirvent, Cristina Diaz-de-Heredia, Susana Rives, Christian M. Zwaan

https://doi.org/10.3324/haematol.2023.284409

Letters to the Editor

Acute myeloid leukemia driven IL-3-dependent upregulation of BCL2 in non-malignant hematopoietic stem and progenitor cells increases venetoclax-induced cytopenias (397 Online Views)

Dominic J. Fowler-Shorten, Rebecca S. Maynard, Katherine Hampton, Annalisa Altera, Matthew Markham, Martha Ehikioya, Edyta E. Wojtowicz, Kristian M. Bowles, Stuart A. Rushworth, Charlotte Hellmich

https://doi.org/10.3324/haematol.2023.283944

Case Reports

Dec 28, 2023

Articles

LNK/SH2B3 as a novel driver in juvenile myelomonocytic leukemia (713 Online Views)

Astrid Wintering, Anna Hecht, Julia Meyer, Eric B. Wong, Juwita Hübner, Sydney Abelson, Kira Feldman, Vanessa E. Kennedy, Cheryl A.C. Peretz, Deborah L. French, Jean Ann Maguire, Chintan Jobaliya, Marta Rojas Vasquez, Sunil Desai, Robin Dulman, Eneida Nemecek, Hilary Haines, Mahmoud Hammad, Alaa El Haddad, Scott C. Kogan, Zied Abdullaev, Farid F. Chehab, Sarah K. Tasian, Catherine C. Smith, Mignon L. Loh, Elliot Stieglitz

https://doi.org/10.3324/haematol.2023.283776

TLR3 agonism augments CD47 inhibition in acute myeloid leukemia (566 Online Views)

Haley E. Ramsey, Agnieszka E. Gorska, Brianna N. Smith, Andrew J. Monteith, Londa Fuller, Maria P. Arrate, Michael R. Savona

https://doi.org/10.3324/haematol.2023.283850

Letters to the Editor

Efficacy of combined low-dose ruxolitinib and cyclosporine in murine immune bone marrow failure (338 Online Views)

Xingmin Feng, Ash Lee Manley, Zhijie Wu, Haoran Li, Shouguo Gao, Jibran Durrani, Nidhi Aggarwal, Hiroki Mizumaki, Jichun Chen, Neal S. Young, Emma M. Groarke

https://doi.org/10.3324/haematol.2023.284358

Dec 21, 2023

Editorials

Articles

Epigenetic dysregulation of eukaryotic initiation factor 3 subunit E (eIF3E) by lysine methyltransferase REIIBP confers a pro-inflammatory phenotype in t(4;14) myeloma (446 Online Views)

Phyllis S.Y. Chong, Jing Yuan Chooi, Sze Lynn Julia Lim, Tae-Hoon Chung, Reinhard Brunmeir, Aaron Chung Yong Leow, Sabrina Hui Min Toh, Kalpnaa Balan, Muhamad Irfan Bin Azaman, Zhengwei Wu, Nagavidya Subramaniam, Leah A Vardy, Wee-Joo Chng

https://doi.org/10.3324/haematol.2023.283467

Histone deacetylase inhibition sensitizes p53-deficient B-cell precursor acute lymphoblastic leukemia to chemotherapy (525 Online Views)

Willem P.J. Cox, Nils Evander, Dorette S. van Ingen Schenau, Gawin R. Stoll, Nadia Anderson, Lieke de Groot, Kari J.T. Grünewald, Rico Hagelaar, Miriam Butler, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

https://doi.org/10.3324/haematol.2023.284101

Letters to the Editor

Home time among older adults with acute myeloid leukemia by therapy intensity (312 Online Views)

Christopher E. Jensen, Allison M. Deal, Alexis C. Wardell, Hillary M. Heiling, Konan E. Beke, Daniel R. Richardson

https://doi.org/10.3324/haematol.2023.284133

Dec 14, 2023

Editorials
Article

Impact of mild thrombocytopenia on bleeding and recurrent thrombosis in cancer (419 Online Views)

Rushad Patell, Charles Hsu, Minggao Shi, Michael A. Grosso, Anil Duggal, Harry R. Buller, Gary Raskob, Jeffrey I. Zwicker

https://doi.org/10.3324/haematol.2023.284192

Editorials

Articles

Multi-gene measurable residual disease assessed by digital polymerase chain reaction has clinical and biological utility in acute myeloid leukemia patients receiving venetoclax/azacitidine (785 Online Views)

Amanda C. Winters, Mohd Minhajuddin, Brett M. Stevens, Ajay Major, Grace Bosma, Diana Abbott, Nicholas Miltgen, Ji Yuan, Amy L. Treece, Bradford J. Siegele, Mark D. Ewalt, Jonathan A. Gutman, Craig T. Jordan, Daniel A. Pollyea

https://doi.org/10.3324/haematol.2023.283790

Epeleuton, a novel synthetic ω-3 fatty acid, reduces the hypoxia/reperfusion stress in a mouse model of sickle cell disease (449 Online Views)

Alessandro Mattè, Enrica Federti, Antonio Recchiuti, Moayed Hamza, Giulia Ferri, Veronica Riccardi, Jacopo Ceolan, Alice Passarini, Filippo Mazzi, Angela Siciliano, Deepak L Bhatt, David Coughlan, John Climax, Elisa Gremese, Carlo Brugnara, Lucia De Franceschi

https://doi.org/10.3324/haematol.2023.284028

Guidelines

Dec 7, 2023

Editorials
Letter to the Editor

A study of 28 pregnant women with sickle cell disease and COVID-19: elevated maternal and fetal morbidity rates (279 Online Views)

Laure Joseph, Gonzalo De Luna, Emmanuelle Bernit, Pierre Cougoul, Aline Santin, Benoit Faucher, Anoosha Habibi, Alain Garou, Gylna Loko, Sarah Mattioni, Sandra Manceau, Jean Benoit Arlet, François Lionnet

https://doi.org/10.3324/haematol.2023.283300

Articles

CASZ1 upregulates PI3K-AKT-mTOR signaling and promotes T-cell acute lymphoblastic leukemia (1026 Online Views)

Bruno A. Cardoso, Mafalda Duque, Ana Gírio, Rita Fragoso, Mariana L. Oliveira, James R. Allen, Leila R. Martins, Nádia C. Correia, André Bortolini Silveira, Alexandra Veloso, Shunsuke Kimura, Lisa Demoen, Filip Matthijssens, Sima Jeha, Cheng Cheng, Ching-Hon Pui, Ana R. Grosso, João L. Neto, Sérgio F. de Almeida, Pieter Van Vlieberghe, Charles G. Mullighan, J. Andres Yunes, David M. Langenau, Françoise Pflumio, João T. Barata

https://doi.org/10.3324/haematol.2023.282854

Granulocyte transfusions in severe aplastic anemia (945 Online Views)

Roma V. Rajput, Vaani Shah, Ruba N. Shalhoub, Kamille West-Mitchell, Nu Ri Cha, Cathy Conry-Cantilena, Susan F. Leitman, David J. Young, Brian Wells, Georg Aue, Cynthia E. Dunbar, Bhavisha A. Patel, Richard W. Childs, Neal S. Young, Colin O. Wu, Emma M. Groarke, Shelley S. Kalsi

https://doi.org/10.3324/haematol.2023.283826

MicroRNA and long non-coding RNA analysis in IgM monoclonal gammopathies reveals epigenetic influence on cellular functions and oncogenesis (282 Online Views)

Karan Chohan, Jonas Paludo, Surendra Dasari, Patrizia Mondello, Joseph P Novak, Jithma P. Abeykoon, Kerstin Wenzl, Zhi-Zhang Yang, Shahrzad Jalali, Jordan E Krull, Esteban Braggio, Michelle K. Manske, Aneel Paulus, Craig B. Reeder, Sikander Ailawadhi, Asher Chanan-Khan, Prashant Kapoor, Robert A. Kyle, Morie A Gertz, Anne J. Novak, Stephen M. Ansell

https://doi.org/10.3324/haematol.2023.283927

PELI2 regulates early B-cell progenitor differentiation and related leukemia via the IL-7R expression (487 Online Views)

Yan Xu, Qian Zhou, Xiaoming Wang, Aijun Zhang, Wentao Qi, Yuan Li, Chengzu Zheng, Jianmin Guan, Tao Sun, Jingxin Li, Chunhua Lu, Yuemao Shen, Baobing Zhao

https://doi.org/10.3324/haematol.2023.284041

Differences in venous clot structures between hemophilic mice treated with emicizumab versus factor VIII or factor VIIIFc (710 Online Views)

Thibaud Sefiane, Hortense Maynadié, Carmen Escurola Ettingshausen, Vincent Muczynski, Xavier Heiligenstein, Julien Dumont, Olivier D. Christophe, Cécile V. Denis, Caterina Casari, Peter J. Lenting

https://doi.org/10.3324/haematol.2023.284142

Impact of inotuzumab ozogamicin on outcome in relapsed or refractory acute B-cell lymphoblastic leukemia patients prior to allogeneic hematopoietic stem cell transplantation and risk of sinusoidal obstruction syndrome/venous occlusive disease (709 Online Views)

Sabine Kayser, Chiara Sartor, Fabio Giglio, Alessandro Bruno, Jonathan Webster, Patrizia Chiusolo, Francesco Saraceni, Selene Guerzoni, Lara Pochintesta, Erika Borlenghi, Giovanni Marconi, Irene Zacheo, Marco Cerrano, Prassede Salutari, Francesco Restuccia, Mariachiara Abbenante, Mark J. Levis, Richard F. Schlenk, Cristina Papayannidis

https://doi.org/10.3324/haematol.2023.284310

Nov 30, 2023

Articles

Real-world multiple myeloma risk factors and outcomes by non-Hispanic Black/African American and non-Hispanic White race/ethnicity in the United States (586 Online Views)

Tondre Buck, Monique A. Hartley-Brown, Yvonne A. Efebera, Carter P. Milner, Jeffrey A. Zonder, Paul G. Richardson, Taylor Salinardi, Megan S. Rice

https://doi.org/10.3324/haematol.2023.282788

Long-term analysis of the RiBVD phase II trial reveals the unfavorable impact of TP53 mutations and hypoalbuminemia in older adults with mantle cell lymphoma; for the LYSA group (400 Online Views)

Sylvain Carras, Alexia Torroja, Anouk Emadali, Emilie Montaut, Nicolas Daguindau, Adrian Tempescul, Anne Moreau, Emmanuelle Tchernonog, Anna Schmitt, Roch Houot, Caroline Dartigeas, Sarah Barbieux, Selim Corm, Anne Banos, Ludovic Fouillet, Jehan Dupuis, Margaret Macro, Joel Fleury, Fabrice Jardin, Clementine Sarkozy, Ghandi Damaj, Pierre Feugier, Luc Matthieu Fornecker, Cecile Chabrot, Veronique Dorvaux, Krimo Bouabdallah, Sandy Amorim, Reda Garidi, Laurent Voillat, Bertrand Joly, Nadine Morineau, Marie Pierre Moles, Hacene Zerazhi, Jean Fontan, Yazid Arkam, Magda Alexis, Vincent Delwail, Jean Pierre Vilque, Loic Ysebaert, Barbara Burroni, Mary Callanan, Steven Le Gouill, Rémy Gressin

https://doi.org/10.3324/haematol.2023.283724

Matching-adjusted indirect comparison from the Lymphoma Epidemiology of Outcomes Consortium for Real World Evidence (LEO CReWE) study to a clinical trial of mosunetuzumab in relapsed or refractory follicular lymphoma (823 Online Views)

Matthew J. Maurer, Carla Casulo, Melissa C. Larson, Thomas M. Habermann, Izidore S. Lossos, Yucai Wang, Loretta J. Nastoupil, Christopher Strouse, Dai Chihara, Peter Martin, Jonathon B. Cohen, Brad S. Kahl, W Richard Burack, Jean L. Koff, Yong Mun, Anthony Masaquel, Mei Wu, Michael C. Wei, Ashwini Shewade, Jia Li, James R. Cerhan, Brian K. Link, Christopher R. Flowers

https://doi.org/10.3324/haematol.2023.283737

Recovery of uninvolved heavy/light chain pair immunoparesis in newly diagnosed transplant-eligible myeloma patients complements the prognostic value of minimal residual disease detection (491 Online Views)

Sunil Lakhwani, Laura Rosiñol, Noemí Puig, Miguel-Angel Pico-Picos, Laura Medina-González, Joaquín Martínez-López, Bruno Paiva, María-Teresa Cedena, Albert Oriol, Rafael Ríos-Tamayo, María-Jesús Blanchard, Isidro Jarque, Joan Bargay, José-María Moraleda, Estrella Carrillo-Cruz, Anna Sureda, Isabel Krsnik, Esther González, Luis Felipe Casado, Josep M Martí, Cristina Encinas, Felipe De Arriba, Luis Palomera, Antonia Sampol, Yolanda González-Montes, Cristina Motlló, Javier De La Cruz, Rafael Alonso, María-Victoria Mateos, Joan Bladé, Juan-José Lahuerta, Jesús San-Miguel, Miguel-Teodoro Hernández

https://doi.org/10.3324/haematol.2023.284154

Effect of delayed cell infusion in patients with large B-cell lymphoma treated with chimeric antigen receptor T-cell therapy (1160 Online Views)

Andrew P. Jallouk, Naishu Kui, Ryan Sun, Jason R. Westin, Raphael E. Steiner, Ranjit Nair, Loretta J. Nastoupil, Luis E. Fayad, Ajlan Al Zaki, Misha Hawkins, Sherry Adkins, Mansoor Noorani, Kaberi Das, Jared Henderson, Elizabeth J. Shpall, Partow Kebriaei, Jeremy Ramdial, Christopher R. Flowers, Sattva S. Neelapu, Sairah Ahmed, Paolo Strati

https://doi.org/10.3324/haematol.2023.284453

Letters to the Editor

Deciphering the molecular complexity of the IKZF1plus genomic profile using Optical Genome Mapping (510 Online Views)

Jonathan L. Lühmann, Martin Zimmermann, Winfried Hofmann, Anke K. Bergmann, Anja Möricke, Gunnar Cario, Martin Schrappe, Brigitte Schlegelberger, Martin Stanulla, Doris Steinemann

https://doi.org/10.3324/haematol.2023.284115

Case Reports

B-cell acute lymphoblastic leukemia and juvenile xanthogranuloma in a patient with ETV6 thrombocytopenia and leukemia predisposition syndrome: novel clinical presentation and perspective (308 Online Views)

Haley Newman, Suzanne P. MacFarland, Garrett M. Brodeur, Timothy Olson, Deepa Bhojwani, Jamie Stokke, Alexandra E. Kovach, Mary Egan Clark, Minjie Luo, Marilyn Li, Amish Shah, Stephen P. Hunger

https://doi.org/10.3324/haematol.2023.284151

Nov 23, 2023

Articles

Massive parallel sequencing unveils homologous recombination deficiency in follicular dendritic cell sarcoma (598 Online Views)

Luisa Lorenzi, Torsten Haferlach, Luigi Mori, Matteo Simbeni, Wencke Walter, Piera Balzarini, Manja Meggendorfer, Claudia Döring, Silvia Lonardi, Mattia Bugatti, Claudio Agostinelli, Jay Mehta, Anita Borges, Abbas Agaimy, Ingrid Simonitsch-Klupp, José Cabeçadas, Elias Campo, Stefano Aldo Pileri, Fabio Facchetti, Martin Leo Hansmann, Sylvia Hartmann

https://doi.org/10.3324/haematol.2023.283669

Nov 16, 2023

Editorials
Article

Autologous-allogeneic versus autologous tandem stem cell transplantation and maintenance therapy with thalidomide for multiple myeloma patients less than 60 years of age: a prospective phase II study (1007 Online Views)

Nicolaus Kröger, Gerald Wulf, Ute Hegenbart, Andreas Burchert, Matthias Stelljes, Nico Gagelmann, Arne Brecht, Martin Kaufmann, Lutz Müller, Arnold Ganser, Dominik Wolf, Wolfgang Bethge, Martin Bornhäuser, Michael Kiehl, Eva-Maria Wagner, Christoph Schmid, Hans Christian Reinhardt, Guido Kobbe, Hans Salwender, Thomas Heinicke, Martin Kropff, Marion Heinzelmann, Francis Ayuk, Lorenz Trümper, Andreas Neubauer, Andreas Völp, Evgeny Kluychnikov, Stefan Schönland, Christine Wolschke

https://doi.org/10.3324/haematol.2023.282920

Editorials
Article

Outcomes of limited stage primary bone diffuse large B-cell lymphoma in the rituximab era: a multicenter, retrospective study (563 Online Views)

Alexandra Rezazadeh, Aniko Szabo, Arushi Khurana, David J. Inwards, Matthew A. Lunning, Nancy L. Bartlett, Paolo F. Caimi, Thomas D. Rodgers, Paul M. Barr, Sayan Mullick Chowdhury, Narendranath Epperla, Hiruni Mendries, Brian T. Hill, Timothy S. Oh, Reem Karmali, Julie E. Chang, Gaurav Goyal, Benjamin M. Parsons, Krista M. Isaac, Craig A. Portell, Kathleen Monahan, Malika Siker, David M. King, Timothy S. Fenske

https://doi.org/10.3324/haematol.2023.283210

Articles

STAT5B mutations in myeloid neoplasms differ by disease subtypes but characterize a subset of chronic myeloid neoplasms with eosinophilia and/or basophilia (466 Online Views)

C. Cameron Yin, Wayne Tam, Serena M. Walker, Amandeep Kaur, Madhu M. Ouseph, Wei Xie, Olga K.Weinberg, Peng Li, Zhuang Zuo, Mark J. Routbort, Simon Chen, L. Jeffrey Medeiros, Tracy I George, Attilio Orazi, Daniel A. Arber, Adam Bagg, Robert P. Hasserjian, Sa A. Wang

https://doi.org/10.3324/haematol.2023.284311

A prospective, multicenter study on hematopoietic stem-cell mobilization with cyclophosphamide plus granulocyte colony-stimulating factor and 'on-demand' plerixafor in multiple myeloma patients treated with novel agents (563 Online Views)

Roberto Mina, Maria Teresa Petrucci, Francesca Bonello, Velia Bongarzoni, Riccardo Saccardi, Giuseppe Bertuglia, Andrea Mengarelli, Andrea Spadaro, Chiara Lisi, Paola Curci, Roberto Massimo Lemoli, Stelvio Ballanti, Rita Floris, Luca Cupelli, Patrizia Tosi, Attilio Olivieri, Delia Rota-Scalabrini, Clotilde Cangialosi, Chiara Nozzoli, Barbara Anaclerico, Francesca Fazio, Benedetto Bruno, Katia Mancuso, Paolo Corradini, Giuseppe Milone, Mario Boccadoro

https://doi.org/10.3324/haematol.2023.284023

Germline bi-allelic SH2B3/LNK alteration predisposes to a neonatal juvenile myelomonocytic leukemia-like disorder (601 Online Views)

Chloé Arfeuille, Yoann Vial, Margaux Cadenet, Aurélie Caye-Eude, Odile Fenneteau, Quentin Neven, Adeline A Bonnard, Simone Pizzi, Giovanna Carpentieri, Yline Capri, Katia Girardi, Lucia Pedace, Marina Macchiaiolo, Kamel Boudhar, Monia ben Khaled, Wadih Abou Chahla, Anne Lutun, Mony Fahd, Séverine Drunat, Elisabetta Flex, Jean-Hugues Dalle, Marion Strullu, Franco Locatelli, Marco Tartaglia, Hélène Cavé

https://doi.org/10.3324/haematol.2023.283917

Pharmacologic targeting of the p62 ZZ domain enhances both anti-tumor and bone-anabolic effects of bortezomib in multiple myeloma (590 Online Views)

Silvia Marino, Daniela N. Petrusca, Ryan T. Bishop, Judith L. Anderson, Hayley M. Sabol, Cody Ashby, Justin H. Layer, Annamaria Cesarano, Utpal P. Davé, Fabiana Perna, Jesus Delgado-Calle, John M. Chirgwin, G. David Roodman

https://doi.org/10.3324/haematol.2023.283787

Pilot study of lung cancer screening for survivors of Hodgkin lymphoma (378 Online Views)

Rachel Broadbent, Philip Crosbie, Christopher J. Armitage, Ben Taylor, Sean Tenant, Joseph Mercer, John Radford, Kim Linton

https://doi.org/10.3324/haematol.2023.283287

Nov 9, 2023

Articles

Autologous-allogeneic versus autologous tandem stem cell transplantation and maintenance therapy with thalidomide for multiple myeloma patients less than 60 years of age: a prospective phase II study (1007 Online Views)

Nicolaus Kröger, Gerald Wulf, Ute Hegenbart, Andreas Burchert, Matthias Stelljes, Nico Gagelmann, Arne Brecht, Martin Kaufmann, Lutz Müller, Arnold Ganser, Dominik Wolf, Wolfgang Bethge, Martin Bornhäuser, Michael Kiehl, Eva-Maria Wagner, Christoph Schmid, Hans Christian Reinhardt, Guido Kobbe, Hans Salwender, Thomas Heinicke, Martin Kropff, Marion Heinzelmann, Francis Ayuk, Lorenz Trümper, Andreas Neubauer, Andreas Völp, Evgeny Kluychnikov, Stefan Schönland, Christine Wolschke

https://doi.org/10.3324/haematol.2023.282920

Impaired hemoglobin clearance by sinusoidal endothelium promotes vaso-occlusion and liver injury in sickle cell disease (656 Online Views)

Tomasz W. Kaminski, Omika Katoch, Ziming Li, Corrine B Hanway, Rikesh K Dubey, Adekunle Alagbe, Tomasz Brzoska, Hong Zhang, Prithu Sundd, Gregory J. Kato, Enrico M. Novelli, Tirthadipa Pradhan-Sundd

https://doi.org/10.3324/haematol.2023.283792

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma (658 Online Views)

Stien De Coninck, Renate De Smedt, Beatrice Lintermans, Lindy Reunes, Hansen J. Kosasih, Alexandra Reekmans, Lauren M. Brown, Nadine Van Roy, Bruno Palhais, Juliette Roels, Malaika Van der Linden, Jo Van Dorpe, Panagiotis Ntziachristos, Frederik W. van Delft, Marc R. Mansour, Tim Pieters, Tim Lammens, Barbara De Moerloose, Charles E. de Bock, Steven Goossens, Pieter Van Vlierberghe

https://doi.org/10.3324/haematol.2023.283981

Nov 2, 2023

Editorials
Article

Profiling the activity of the para-caspase MALT1 in B-cell acute lymphoblastic leukemia for potential targeted therapeutic application (859 Online Views)

Firas M. Safa, Terri Rasmussen, Lorena Fontan, Min Xia, Ari Melnick, Adrian Wiestner, Patricia Lobelle-Rich, Jan A. Burger, Yara Mouawad, Hana Safah, Erik K Flemington, Nakhle S. Saba

https://doi.org/10.3324/haematol.2023.283178

Spotlight Review

Articles

ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms (828 Online Views)

Vladimir Riabov, Qingyu Xu, Nanni Schmitt, Alexander Streuer, Guo Ge, Lyndsey Bolanos, Mark Wunderlich, Johann-Christoph Jann, Alina Wein, Eva Altrock, Marie Demmerle, Sanjay Mukherjee, Abdullah Mahmood Ali, Felicitas Rapp, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Ahmed Jawhar, Ali Darwich, Patrick Wuchter, Christel Weiss, Azra Raza, Jason M. Foulks, Daniel T Starczynowski, Feng-Chun Yang, Georgia Metzgeroth, Laurenz Steiner, Mohamad Jawhar, Wolf-Karsten Hofmann, Daniel Nowak

https://doi.org/10.3324/haematol.2023.282921

SH2 domain-containing inositol 5-phosphatases support the survival of Burkitt lymphoma cells by promoting energy metabolism (681 Online Views)

Florian Mayr, Vanessa Kruse, Dominik C. Fuhrmann, Sebastian Wolf, Jens Löber, Saed Alsouri, Nadia Paglilla, Kwang Lee, Björn Chapuy, Bernhard Brüne, Thorsten Zenz, Björn Häupl, Thomas Oellerich, Michael Engelke

https://doi.org/10.3324/haematol.2023.283663

Oct 26, 2023

Articles

Impact of race and ethnicity on early mortality in multiple myeloma: a SEER analysis (696 Online Views)

John X. Wei, Aditi Shastri, R. Alejandro Sica, Ioannis Mantzaris, Noah Kornblum, Urvi Shah, Murali Janakiram, Kira Gritsman, Amit Verma, Mendel Goldfinger, Dennis Cooper, Nishi Shah

https://doi.org/10.3324/haematol.2023.283304

A Japanese retrospective study of non-tuberculous mycobacterial infection in children, adolescents, and young adult patients with hematologic-oncologic diseases (587 Online Views)

Yusuke Tsumura, Hideki Muramatsu, Nobuyuki Tetsuka, Takahiro Imaizumi, Kikue Sato, Kento Inoue, Yoshitomo Motomura, Yuko Cho, Daiki Yamashita, Daichi Sajiki, Ryo Maemura, Ayako Yamamori, Masayuki Imaya, Manabu Wakamatsu, Kotaro Narita, Shinsuke Kataoka, Motoharu Hamada, Rieko Taniguchi, Eri Nishikawa, Atsushi Narita, Nobuhiro Nishio, Seiji Kojima, Yoshihiko Hoshino, Yoshiyuki Takahashi

https://doi.org/10.3324/haematol.2023.283636

Overall survival and causes of death in elderly patients with Hodgkin lymphoma: a Norwegian population-based case-control study (425 Online Views)

Kjersti Lia, Rasmus R.K. Jørgensen, Bente L.Wold, Øystein Fluge, Unn-Merete Fagerli, Hanne Bersvendsen, Idun B. Bø, Sameer Bhargava, Alexander Fosså

https://doi.org/10.3324/haematol.2023.283721

Case Reports

Cerebral venous sinus thrombosis and thrombocytopenia due to heparin-independent anti-PF4 antibodies after adenovirus infection (842 Online Views)

Günalp Uzun, Jan Zlamal, Karina Althaus, Andrea Bevot, Florian Hennersdorf, Nina Wolska, Anna Jock, Jan Kern, Vanya Icheva, Sven Poli, Ulrike Ernemann, Andreas Neu, Tamam Bakchoul

https://doi.org/10.3324/haematol.2023.284127

Oct 19, 2023

Articles

Outcomes of limited stage primary bone diffuse large B-cell lymphoma in the rituximab era: a multicenter, retrospective study (563 Online Views)

Alexandra Rezazadeh, Aniko Szabo, Arushi Khurana, David J. Inwards, Matthew A. Lunning, Nancy L. Bartlett, Paolo F. Caimi, Thomas D. Rodgers, Paul M. Barr, Sayan Mullick Chowdhury, Narendranath Epperla, Hiruni Mendries, Brian T. Hill, Timothy S. Oh, Reem Karmali, Julie E. Chang, Gaurav Goyal, Benjamin M. Parsons, Krista M. Isaac, Craig A. Portell, Kathleen Monahan, Malika Siker, David M. King, Timothy S. Fenske

https://doi.org/10.3324/haematol.2023.283210

Factors associated with refractoriness or early progression after idecabtagene vicleucel in patients with relapsed/refractory multiple myeloma: U.S. Myeloma Immunotherapy Consortium real world experience (1252 Online Views)

Hamza Hashmi, Doris K. Hansen, Lauren C. Peres, Omar Castaneda Puglianini, Ciara Freeman, Gabriel De Avila, Surbhi Sidana, Leyla Shune, Douglas W. Sborov, James Davis, Charlotte Wagner, Mehmet H. Kocoglu, Shebli Atrash, Peter Voorhees, Gary Simmons, Christopher Ferreri, Nilesh Kalariya, Larry D. Anderson Jr., Aimaz Afrough, Danai Dima, Jack Khouri, Joseph McGuirk, Fred Locke, Rachid Baz, Krina K. Patel, Melissa Alsina

https://doi.org/10.3324/haematol.2023.283888

Differential transcriptional control of hematopoiesis in congenital and cyclic neutropenia patients harboring ELANE mutations (550 Online Views)

Alexander Zeidler, Natalia Borbaran-Bravo, Benjamin Dannenmann, Malte Ritter, Masoud Nasri, Maksim Klimiankou, Sergey Kandabarau, Azadeh Zahabi, Josef König, Cornelia Zeidler, Julia Skokowa, Karl Welte

https://doi.org/10.3324/haematol.2023.284033

Impact of mild thrombocytopenia on bleeding and recurrent thrombosis in cancer (419 Online Views)

Rushad Patell, Charles Hsu, Minggao Shi, Michael A. Grosso, Anil Duggal, Harry R. Buller, Gary Raskob, Jeffrey I. Zwicker

https://doi.org/10.3324/haematol.2023.284192

Letters to the Editor

A study of 28 pregnant women with sickle cell disease and COVID-19: elevated maternal and fetal morbidity rates (279 Online Views)

Laure Joseph, Gonzalo De Luna, Emmanuelle Bernit, Pierre Cougoul, Aline Santin, Benoit Faucher, Anoosha Habibi, Alain Garou, Gylna Loko, Sarah Mattioni, Sandra Manceau, Jean Benoit Arlet, François Lionnet

https://doi.org/10.3324/haematol.2023.283300

Oct 12, 2023

Editorials
Letter to the Editor

Amphiregulin as monitoring biomarker for life-threatening acute graft-versus-host disease: secondary analysis of two prospective clinical trials (413 Online Views)

Shernan G. Holtan, Najla El Jurdi, Armin Rashidi, Brian C. Betts, Connor Demorest, John P Galvin, Margaret L. MacMillan, Daniel J. Weisdorf, Angela Panoskaltsis-Mortari, Michael A. Pratta

https://doi.org/10.3324/haematol.2023.283215

Sep 28, 2023

Articles

Profiling the activity of the para-caspase MALT1 in B-cell acute lymphoblastic leukemia for potential targeted therapeutic application (859 Online Views)

Firas M. Safa, Terri Rasmussen, Lorena Fontan, Min Xia, Ari Melnick, Adrian Wiestner, Patricia Lobelle-Rich, Jan A. Burger, Yara Mouawad, Hana Safah, Erik K Flemington, Nakhle S. Saba

https://doi.org/10.3324/haematol.2023.283178

Sep 14, 2023

Letters to the Editor

Amphiregulin as monitoring biomarker for life-threatening acute graft-versus-host disease: secondary analysis of two prospective clinical trials (413 Online Views)

Shernan G. Holtan, Najla El Jurdi, Armin Rashidi, Brian C. Betts, Connor Demorest, John P Galvin, Margaret L. MacMillan, Daniel J. Weisdorf, Angela Panoskaltsis-Mortari, Michael A. Pratta

https://doi.org/10.3324/haematol.2023.283215

Aug 19, 2021

Errata Corrige

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma (3564 Online Views)

Johannes Duell, Kami J. Maddocks, Eva González-Barca, Wojciech Jurczak, Anna Marina Liberati, Sven de Vos, Zsolt Nagy, Aleš Obr, Gianluca Gaidano, Pau Abrisqueta, Nagesh Kalakonda, Marc André, Martin Dreyling, Tobias Menne, Olivier Tournilhac, Marinela Augustin, Andreas Rosenwald, Maren Dirnberger-Hertweck, Johannes Weirather, Sumeet Ambarkhane, Gilles Salles

https://doi.org/10.3324/haematol.2021.279802

May 10, 2018

Articles

GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells (1327 Online Views)

Beibei Zhang, Pilar Ayuda Durán, Laure Piechaczyk, Yngvar Fløisand, Mireia Mayoral Safont Safont, Ida Tveit Karlsen, Zina Fandalyuk, Dagim Tadele, Pepijn van Mierlo, Alexander D. Rowe, Joseph M. Robertson, Bjørn Tore Gjertsen, Emmet McCormack, Jorrit M. Enserink, Bjørn Tore Gjertsen Group, Emmet McCormack Group

https://doi.org/10.3324/haematol.2018.189399