Early view

Nov 28, 2024

Articles

Intracranial hemorrhage before start of prophylaxis in children with hemophilia: incidence, timing, and potential for prevention (118 Online Views)

Nadine G. Andersson, Marloes de Kovel, Giancarlo Castaman, Roseline d’Oiron, Gili Kenet, Christoph Konigs, Christoph Male, Beatrice Nolan, Martin Olivieri, Fernando Pinto, Sigridur Sigurgisladottir, Ester Zapotocka, Kathelijn Fischer

https://doi.org/10.3324/haematol.2024.285874

A fully humanized von Willebrand disease type 1 mouse model as unique platform to investigate novel therapeutic options (87 Online Views)

Genevieve McCluskey, Marco Heestermans, Ivan Peyron, Eloise Pascal, Marie Clavel, Eric Bun, Emilie Bocquet, Christelle Reperant, Sophie Susen, Olivier D. Christophe, Cecile V. Denis, Peter J. Lenting, Caterina Casari

https://doi.org/10.3324/haematol.2024.286076

Novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma (109 Online Views)

Aric Anloague, Hayley M. Sabol, Japneet Kaur, Sharmin Khan, Cody Ashby, Carolina Schinke, C. Lowry Barnes, Farah Alturkmani, Elena Ambrogini, Michael Tveden Gundesen, Thomas Lund, Anne Kristine Amstrup, Thomas Levin Andersen, Marta Diaz-delCastillo, G. David Roodman, Teresita Bellido, Jesus Delgado-Calle

https://doi.org/10.3324/haematol.2024.286484

Letters to the Editor

Donor cytomegalovirus serology impacts overall survival in children receiving first unrelated hematopoietic stem cell transplant for acute leukemia: European Society of Bone Marrow Transplantation Pediatric Diseases Working Party Study (145 Online Views)

Elif Ince, Jaques-Emmanuel Galimard, Marianne Ifversen, Arnaud Dalissier, Zofia Szmit, Oana Mirci-Danicar, Franco Locatelli, Petr Sedlacek, Jan Styczynski, Jean-Hugues Dalle, Cecile Renard, Adriana Balduzzi, Arjan Lankester, Marc Bierings, Franca Fagioli, Katrine Kielsen, Fanny Rialland, Jochen Büchner, Mervi Taskinen, Robert Wynn, Charlotte Jubert, Gérard Michel, Herbert Pichler, Gergely Krivan, Simone Cesaro, Selim Corbacioglu, Roland Meisel, Krzysztof Kalwak

https://doi.org/10.3324/haematol.2024.286082

Dexamethasone is associated with reduced frequency and intensity of cytokine release syndrome compared with alternative corticosteroid regimens as premedication for glofitamab in patients with relapsed / refractory large B-cell lymphoma (130 Online Views)

Lorenzo Falchi, Martin Hutchings, Carmelo Carlo-Stella, Franck Morschhauser, Michael Dickinson, Guillaume Cartron, Cyrus Khan, Monica Tani, Joaquin Martinez-Lopez, Nancy L. Bartlett, Antonio Salar, Joshua D. Brody, Sirpa Leppä, Aurelien Berthier, Martine Kallemeijn, James Relf, Fabiola Bene Tchaleu, Linda Lundberg, Emmanuel Bachy.

https://doi.org/10.3324/haematol.2024.286257

Letermovir prophylaxis for cytomegalovirus is associated with risk of post-transplant lymphoproliferative disorders after haploidentical stem cell transplantation (148 Online Views)

Xu-Ying Pei, Qiang Huang, Ling-Jie Luo, Hai-Lu Sun, Jing Liu, Yu-Qian Sun, Xiao-Dong Mo, Meng Lv, Dai-Hong Liu, Hong-Yan Ma, Yan-Wei Wu, Lan-Ping Xu, Yu Wang, Xiao-Hui Zhang, Liang Chen, Xiao-Jun Huang

https://doi.org/10.3324/haematol.2024.286265

Identification of a clinicopathologic prognostic index for newly diagnosed large B cell lymphoma patients treated with R-CHOP (72 Online Views)

Vincent Ni, Sunita D. Nasta, Stefan K. Barta, Stephen J. Schuster, Elise A. Chong, Jakub Svoboda, Jennifer J.D. Morrissette, Ashley Barlev, Adam Bagg, Salvatore F. Priore, Daniel J. Landsburg

https://doi.org/10.3324/haematol.2024.286560

Isatuximab, pomalidomide, and dexamethasone as salvage therapy for patients with multiple myeloma: the Italian, multicenter, retrospective clinical experience with 270 cases outside of controlled clinical trials (174 Online Views)

Enrica Antonia Martino, Daniele Derudas, Elena Rossi, Sofia Terlizzi, Giovanni Reddiconto, Paola Stefanoni, Jacopo Micozzi, Silvia Mangiacavalli, Elena Zamagni, Massimo Offidani, Anna Furlan, Gabriele Buda, Flavia Lotti, Carmine Liberatore, Antonio Lazzaro, Roberta Della Pepa, Giuseppe Bertuglia, Emiliano Barbieri, Concetta Conticello, Claudio De Magistris, Lorenzo De Paoli, Velia Bongarzoni, Anna Maria Cafro, Anna Mele, Pietro Benvenuti, Claudio Cerchione, Cirino Botta, Elisabetta Antonioli, Nicola Sgherza, Sara Aquino, Giuseppe Mele, Gregorio Barilà, Salvatore Palmieri, Ombretta Annibali, Rosario Bianco, Massimiliano Arangio Febbo, Gloria Margiotta Casaluci, Angela Rago, Raffaele Fontana, Francesca Farina, Ernesto Vigna, Antonella Bruzzese, Katia Mancuso, Davide Nappi, Sonia Morè, Elena Rivolti, Catello Califano, Angela Amendola, Daniela Roccotelli, Alessandra Lombardo, Annalisa Citro, Giuseppina Uccello, Renato Zambello, Alessandro Maggi, Santo Neri, Michele Monachesi, Alessandro Gozzetti, Vittorio Montefusco, Marino Brunori, Emilia Cotzia, Giuseppe Pietrantuono, Angela Maria Quinto, Valeria Amico, Nicola Di Renzo, Marta Coscia, Monica Galli, Valerio De Stefano, Maria Teresa Petrucci, Antonino Neri, Francesco Di Raimondo, Fortunato Morabito, Pellegrino Musto, Massimo Gentile

https://doi.org/10.3324/haematol.2024.286658

Nov 21, 2024

Editorials

Review Articles

Infections in sickle cell disease (313 Online Views)

Lily E.A. Scourfield, Amina Nardo-Marino, Thomas N. Williams, David C. Rees

https://doi.org/10.3324/haematol.2024.285066

Articles

Acute myeloid leukemia drug tolerant persister cells survive chemotherapy by transiently increasing plasma membrane rigidity, that also increases their sensitivity to immune cell killing (256 Online Views)

Yael Morgenstern, JongBok Lee, Yoosu Na, Brandon Y. Lieng, Nicholas S. Ly, William D. Gwynne, Rose Hurren, Li Ma, Dakai Ling, Marcela Gronda, Andrea Arruda, Avraham Frisch, Tsila Zuckerman, Yishai Ofran, Mark D. Minden, Li Zhang, Catherine O’Brien, Andrew T. Quaile, J. Rafael Montenegro-Burke, Aaron D. Schimmer

https://doi.org/10.3324/haematol.2024.286018

Predictors and implications of renal injury after CD19 chimeric antigen receptor T-cell therapy (389 Online Views)

Alexander P. Boardman, Victoria Gutgarts, Jessica Flynn, Sean M. Devlin, Adam Goldman, Ana Alarcon Tomas, Joshua A. Fein, John B. Slingerland, Allison Parascondola, Richard J. Lin, Michael Scordo, Parastoo B. Dahi, Sergio Giralt, M. Lia Palomba, Gilles Salles, Karthik Nath, Moneeza Walji, Magdalena Corona, Jae H. Park, Gunjan L. Shah, Miguel-Angel Perales, Insara Jaffer-Sathick, Roni Shouval

https://doi.org/10.3324/haematol.2024.286021

Investigating the influence of germline ATM variants in chronic lymphocytic leukemia on cancer vulnerability (158 Online Views)

Roberta S. Azevedo, Francesca Morelli, Kiyomi Mashima, Rayan Fardoun, Svitlana Tyekucheva, Stacey Fernandes, Samantha Shupe, Marissa Terra, Anisha Patel, Matthew S. Davids, Joseph Yu, Jennifer R. Brown

https://doi.org/10.3324/haematol.2024.286031

Targeting P-selectin and interleukin-1β in mice with sickle cell disease: effects on vaso-occlusion, liver injury and organ iron deposition (246 Online Views)

Érica M. F. Gotardo, Lidiane S. Torres, Bruna Cunha Zaidan, Lucas F. S. Gushiken, Pâmela L. Brito, Flavia C. Leonardo, Claudia H. Pellizzon, John Millholland, Sergei Agoulnik, Jiri Kovarik, Fernando F. Costa, Nicola Conran

https://doi.org/10.3324/haematol.2024.286418

Letters to the Editor

FLT3 ligand kinetic profile predicts response to treatment in patients with high-risk myelodysplastic syndrome / chronic myelomonocytic leukemia receiving CPX-351: a study from the Groupe Francophone des Myélodysplasies (169 Online Views)

Pierre Peterlin, Joëlle Gaschet, Pascal Turlure, Marie-Pierre Gourin, Pierre-Yves Dumas, Sylvain Thepot, Ana Berceanu, Sophie Park, Marie-Anne Hospital, Thomas Cluzeau, Jose-Miguel Torregrosa-Diaz, Louis Drevon, Rosa Sapena, Fatiha Chermat, Lionel Ades, Sophie Dimicoli-Salazar, Maxime Jullien, Pierre Fenaux, Patrice Chevallier.

https://doi.org/10.3324/haematol.2024.286025

Teclistamab in relapsed refractory multiple myeloma: a multi-institutional real-world study from the French early access program (253 Online Views)

Aurore Perrot, Cyrille Hulin, Ariane Boumendil, Hamza Manjra, Antoine Leveque, Carolyne Croizier, Arthur Dony, Mohamad Mohty, Murielle Roussel, Salomon Manier, Frédérique Orsini-Piocelle, Loic Bauschert, Arthur Bobin, Laurent Frenzel, Laure Vincent, Claire Breal, Jean Richard Eveillard, Thomas Gerome, Mourad Tiab, Emilie Chalayer, Rakiba Belkhir, Clara Mariette, Perrine Moyer, Thomas Chalopin, Brieuc Cherel, Lydia Montes, Arthur Coste, Reza Tabrizi, Lionel Karlin, Daniella Robu, Amandine Huguet, Stéphanie Harel, Philippe Moreau

https://doi.org/10.3324/haematol.2024.286118

Calaspargase pegol and pegaspargase cause similar hepatosteatosis in mice (71 Online Views)

Veronica Ruiz-Torres, Jennifer J. Chia, Michael Cohen, Jia Tan, Teresa Rushing, Jose Tinajero, Etan Orgel, Steven D. Mittelman

https://doi.org/10.3324/haematol.2024.286549

Nov 14, 2024

Editorials
Letter to the Editor

Polytypic B cells, monotypic/monoclonal B-cell proliferations, and neoplastic T cells diverge from TET2-/DNMT3A-mutant clonal hematopoiesis in follicular helper T-cell lymphomas (770 Online Views)

Natasha E. Lewis, Kseniya Petrova-Drus, Rohan Sardana, Sarah Huet, Qi Gao, Shenon Sethi, Chad Vanderbilt, Wenbin Xiao, Mikhail Roshal, Jeeyeon Baik, Himanshu Bhurtel, Alison J. Moskowitz, Steven M. Horwitz, Ahmet Dogan

https://doi.org/10.3324/haematol.2024.285183

Editorials

Editorials
Article

Long-term survival can be achieved in a significant fraction of older patients with core binding factor acute myeloid leukemia treated with intensive chemotherapy (671 Online Views)

Federico Mosna, Erika Borlenghi, Mark Litzow, John C. Byrd, Cristina Papayannidis, Cristina Tecchio, Felicetto Ferrara, Guido Marcucci, Roberto Cairoli, Elizabeth A. Morgan, Carmela Gurrieri, Cecilia C.S. Yeung, H. Joachim Deeg, Debora Capelli, Anna Candoni, Jason R. Gotlib, Monia Lunghi, Sheeja Pullarkat, Francesco Lanza, Sara Galimberti, Fabio Forghieri, Adriano Venditti, Moreno Festuccia, Ernesta Audisio, Denise Marvalle, Gian Matteo Rigolin, Giovanni Roti, Eros DiBona, Giuseppe Visani, Francesco Albano, Ann-Kathrin Eisfeld, Peter Valent, Gerwin Huls, Gautam Borthakur, Mauro Krampera, Giovanni Martinelli, Nicolaus Kröger, Alessandra Sperotto, Michele Gottardi

https://doi.org/10.3324/haematol.2024.285448

Editorials
Article

Lysine succinylation precisely controls normal erythropoiesis (466 Online Views)

Bin Hu, Han Gong, Ling Nie, Ji Zhang, Yanan Li, Dandan Liu, Huifang Zhang, Haihang Zhang, Lu Han, Chaoying Yang, Maohua Li, Wenwen Xu, Yukio Nakamura, Lihong Shi, Mao Ye, Christopher D. Hillyer, Narla Mohandas, Long Liang, Yue Sheng, Jing Liu

https://doi.org/10.3324/haematol.2024.285752

Review Articles

Articles

Challenges associated with access to recently developed hemophilia treatments in routine care: perspectives of healthcare professionals (139 Online Views)

Karin Berger, Roxy H. O’Rourke, Matteo Nicola Dario Di Minno, Angelika Batorova, Kaan Kavakli, Pier Mannuccio Mannucci, Wolfgang Schramm, Rhonda L. Bohn, Louis Aledort

https://doi.org/10.3324/haematol.2024.285647

Loncastuximab in high-risk and heavily pretreated relapsed/refractory diffuse large B-cell lymphoma: a real-world analysis from 21 US centers (359 Online Views)

Viktoriya Zelikson, Ashwath Gurumurthi, Yazeed Sawalha, Kaitlin Annunzio, Aditi Saha, Ning Dong, David Qualls, Behzad Amoozgar, Brad Kahl, John Baird, Pavan Challa, Scott F. Huntington, Jennifer Santos, Steven Bair, Mayur Narkhede, Shuning Li, Zachary Frosch, Carrie Ho, Stephen D. Smith, Allison Winter, Daniel Landsburg, Fateeha Furqan, Mehdi Hamadani, Katelin Baird, Jason Romancik, Hanan Alharthy, Jennie Law, Leyla Bojanini, Ranjana Advani, Boyu Hu, Patrick Connor Johnson, Natalie S. Grover, Mwanasha Merril, Jennifer L. Crombie, Nazila Shafagati, Cole Sterling, Loretta J. Nastoupil, Narendranath Epperla, Emily C. Ayers

https://doi.org/10.3324/haematol.2024.285977

Letters to the Editor

Ixazomib, pomalidomide and dexamethasone in relapsed or refractory multiple myeloma characterized with high-risk cytogenetics: the IFM 2014-01 study (320 Online Views)

Arthur Bobin, Salomon Manier, Joe de Keizer, Jaydeep K. Srimani, Cyrille Hulin, Lionel Karlin, Denis Caillot, Ingrid Lafon, Clara Mariette, Carla Araujo, Bertrand Arnulf, Benoît Bareau, Karim Belhadj, Lofti Benboubker, Thorsten Braun, Claire Calmettes, Olivier Decaux, Mamoun Dib, Hélène Demarquette, Caroline Jacquet, Cécile Sonntag, Sophie Godet, Arnaud Jaccard, Pascal Lenain, Margaret Macro, Valentine Richez-Olivier, Mourad Tiab, Laure Vincent, Hacene Zerazhi, Marie-Odile Pétillon, Sandrine Rollet, Helene Gardeney, Geraldine Durand, Anthony Levy, Cyrille Touzeau, Aurore Perrot, Philippe Moreau, Thierry Facon, Jill Corre, Stephanie Ragot, Herve Avet-Loiseau, Xavier Leleu

https://doi.org/10.3324/haematol.2024.285916

Germline genetics, disease, and exposure to medication influence longitudinal dynamics of clonal hematopoiesis (416 Online Views)

Taralynn Mack, Yash Pershad, Caitlyn Vlasschaert, Cosmin A. Bejan, Jonathan Brett Heimlich, Yajing Li, Nicole A. Mickels, Joseph C. Van Amburg, Jessica Ulloa, Alexander J. Silver, Leo Y. Luo, Angela Jones, Paul Brent Ferrell, Ashwin Kishtagari, Yaomin Xu, Michael R. Savona, Alexander G. Bick

https://doi.org/10.3324/haematol.2024.286513

Nov 7, 2024

Spotlight Review

Articles

Outcomes with intensive treatment for acute myeloid leukemia: an analysis of two decades of data from the HARMONY Alliance (1010 Online Views)

Marta Anna Sobas, Amin T. Turki, Angela Villaverde Ramiro, Alberto Hernández-Sánchez, Javier Martinez Elicegui, Teresa González, Raúl Azibeiro Melchor, María Abáigar, Laura Tur, Daniele Dall'Olio, Eric Sträng, Jesse M. Tettero, Gastone Castellani, Axel Benner, Konstanze Döhner, Christian Thiede, Klaus H. Metzeler, Torsten Haferlach, Frederik Damm, Rosa Ayala, Joaquín Martínez-López, Ken I Mills, Jorge Sierra, Sören Lehmann, Matteo G. Della Porta, Jiri Mayer, Dirk Reinhardt, Rubén Villoria Medina, Renate Schulze-Rath, Martje Barbus, Jesús María Hernández-Rivas, Brian J.P Huntly, Gert Ossenkoppele, Hartmut Döhner, Lars Bullinger

https://doi.org/10.3324/haematol.2024.285805

Arsenic trioxide versus Realgar-Indigo naturalis formula in non-high-risk acute promyelocytic leukemia: a multicenter, randomized trial (261 Online Views)

Shu Chen, Weiwei Qin, Xiaohong Lu, Li Liu, Yinsuo Zheng, Xinhua Lu, Xiaohui Wang, Xiaojuan Zhang, Sha Gong, Suhua Wei, Huiyun Zhang, Hanru Ding, Ranjbarha Seifollah, Jing Li, Haitao Zhang, Di Wu, Olubukola Abiona, Pengcheng He, Rong Zhang, David Wald, Huaiyu Wang

https://doi.org/10.3324/haematol.2024.285905

Venetoclax in combination with a pediatric-inspired regimen for the treatment of newly diagnosed adults with Philadelphia chromosome-negative acute lymphoblastic leukemia (523 Online Views)

Ibrahim Aldoss, Jianying Zhang, Kathryn Shimamoto, Caner Saygin, Marjorie Robbins, Vaibhav Agrawal, Ahmed Aribi, Diren Arda Karaoglu, Hoda Pourhassan, Paul Koller, Haris Ali, Amanda Blackmon, Salman Otoukesh, Karamjeet Sandhu, Brian Ball, Andrew S. Artz, Monzr M. Al Malki, Amandeep Salhotra, Jose Tinajero, Zhaohui Gu, Ian Lagman, Michelle Velasquez, Jacqueline Dang, Pamela S. Becker, Michelle Afkhami, Lucy Ghoda, Wendy Stock, Stephen J Forman, Anthony Stein, Guido Marcucci, Vinod Pullarkat

https://doi.org/10.3324/haematol.2024.286427

Letters to the Editor

Comparison of EasyM, a clonotypic mass spectrometry assay, and EuroFlow minimal residual disease assessment in multiple myeloma (577 Online Views)

Jessie Zhao, Tiffany Khong, Malgorzata Gorniak, Abir Khaled, Zac McDonald, John Reynolds, Sridurga Mithraprabhu, Nicholas Bingham, Suehli Lim, Daniel Wong, Anna Johnston, Olga Motorna, Nicholas Murphy, Hang Quach, Liqiang Yang, Andrew Spencer

https://doi.org/10.3324/haematol.2024.285933

Cumulative review of hypertension in patients with chronic lymphocytic leukemia treated with acalabrutinib (402 Online Views)

Alessandra Ferrajoli, George Follows, Yotvat Marmor, Jack Roos, Naghmana Bajwa, Venkata Madhira, Kenji Nozaki, Paulo Miranda, Dinci Pennap, Krish Patel

https://doi.org/10.3324/haematol.2024.285757

Oct 31, 2024

Review Articles

Articles

Comparative efficacy of lisocabtagene maraleucel in the PILOT study versus second-line chemotherapy regimens in the real world (319 Online Views)

Nilanjan Ghosh, Alison Sehgal, Fei Fei Liu, Ana Kostic, Alessandro Crotta, Marc De Benedetti, Jillian Faccone, Lily Peng, Leo I. Gordon

https://doi.org/10.3324/haematol.2024.285828

Outcomes of children and young adults with B-cell acute lymphoblastic leukemia given blinatumomab as last consolidation treatment before allogeneic hematopoietic stem cell transplantation (586 Online Views)

Mattia Algeri, Michele Massa, Daria Pagliara, Valentina Bertaina, Federica Galaverna, Ilaria Pili, Giuseppina Li Pira, Roberto Carta, Francesco Quagliarella, Rita M. Pinto, Chiara Rosignoli, Barbarella Lucarelli, Maria G. Cefalo, Emilia Boccieri, Francesca Benini, Francesca Del Bufalo, Marco Becilli, Pietro Merli, Gerhard Zugmaier, Franco Locatelli

https://doi.org/10.3324/haematol.2024.286350

Letters to the Editor

Impact of daratumumab/bortezomib/thalidomide and dexamethasone induction therapy on chemo-free stem cell mobilization in transplant eligible newly diagnosed multiple myeloma: a multicentre real-world experience. (332 Online Views)

Marika Porrazzo, Tiziana Moscato, Giuseppe Sapienza, Fabrizio Accardi, Caterina Patti, Clotilde Cangialosi, Carmelo Costanza, Roberto Bono, Stefania Tringali, Cristina Rotolo, Emilia Gigliotta, Andrea Rizzuto, Manuela Giuseppa Ingrascè, Giulia Butera, Laura Di Noto, Alessandra Santoro, Anna Marfia, Cirino Botta, Sergio Siragusa, Massimo Martino, Luca Castagna

https://doi.org/10.3324/haematol.2024.286332

Early death and intracranial hemorrhage prediction in acute promyelocytic leukemia: validation of a risk score in a chemotherapy plus ATRA cohort from an international consortium (370 Online Views)

Wellington F. Silva, Haesook T Kim, Maria S. Undurraga, Juan R. Navarro-Cabrera, Victor Salinas, Pablo Muxi, Raul A.M. Melo, Ana Beatriz F. Gloria, Katia B.B. Pagnano, Elenaide C. Nunes, Rosane Isabel Bittencourt, Ninoska Rojas, Shirley M.Q. Truyenque, Ana Ilda Ayala-Lugo, Ana Carolina Oliver, Lorena L. Figueiredo-Pontes, Fabiola Traina, Frederico Moreira, Evandro M. Fagundes, Bruno K.L. Duarte, Analí Pamela Mora-Alferez, Percy Ortiz, Jose Luis Untama, Martin S. Tallman, Raul C. Ribeiro, Arnold Ganser, Richard James Dillon, Peter J.M. Valk, Miguel A. Sanz, Bob Löwenberg, Nancy Berliner, Eduardo M. Rego

https://doi.org/10.3324/haematol.2024.286338

Oct 24, 2024

Editorials
Article

BCAT1 is a NOTCH1 target and sustains the oncogenic function of NOTCH1 (585 Online Views)

Valeria Tosello, Ludovica Di Martino, Adonia E. Papathanassiu, Silvia Dalla Santa, Marco Pizzi, Lara Mussolin, Jingjing Liu, Pieter van Vlierberghe, Erich Piovan

https://doi.org/10.3324/haematol.2024.285552

Letters to the Editor

Posterior cerebral circulation in children with sickle cell anemia: an uncharted territory (197 Online Views)

Alvise Fattorello Salimbeni, Ludovica De Rosa, Alessia Volpato, Federica Viaro, Alessio Pieroni, Stefano Mozzetta, Francesco Favruzzo, Alessandra Pes, Matteo Zaccagnino, Giulia Reggiani, Maria Paola Boaro, Raffaella Colombatti, Renzo Manara, Claudio Baracchini

https://doi.org/10.3324/haematol.2024.285773

Review Articles of Review Series on Myelodysplastic Syndromes

Review Articles of Review Series on Myeloproliferative Syndromes

Oct 17, 2024

Editorials
Article

Pirtobrutinib monotherapy in Bruton tyrosine kinase inhibitor-intolerant patients with B-cell malignancies: results of the phase I/II BRUIN trial (1338 Online Views)

Nirav N. Shah, Michael Wang, Lindsey E. Roeker, Krish Patel, Jennifer A. Woyach, William G. Wierda, Chaitra S. Ujjani, Toby A. Eyre, Pier Luigi Zinzani, Alvaro J. Alencar, Paolo Ghia, Nicole Lamanna, Marc S. Hoffmann, Manish R. Patel, Ian Flinn, James N. Gerson, Shuo Ma, Catherine C. Coombs, Chan Y. Cheah, Ewa Lech-Maranda, Bita Fakhri, Won Seog Kim, Minal A. Barve, Jonathon B. Cohen, Wojciech Jurczak, Talha Munir, Meghan C. Thompson, Donald E. Tsai, Katherine Bao, Nicholas A. Cangemi, Jennifer F. Kherani, Richard A. Walgren, Hongmei Han, Amy S. Ruppert, Jennifer R. Brown

https://doi.org/10.3324/haematol.2024.285754

Review Articles

Articles

Lysine succinylation precisely controls normal erythropoiesis (466 Online Views)

Bin Hu, Han Gong, Ling Nie, Ji Zhang, Yanan Li, Dandan Liu, Huifang Zhang, Haihang Zhang, Lu Han, Chaoying Yang, Maohua Li, Wenwen Xu, Yukio Nakamura, Lihong Shi, Mao Ye, Christopher D. Hillyer, Narla Mohandas, Long Liang, Yue Sheng, Jing Liu

https://doi.org/10.3324/haematol.2024.285752

Letters to the Editor

Belantamab mafodotin monotherapy for relapsed or refractory multiple myeloma: a real-world observational study in the United States (463 Online Views)

Malin Hultcrantz, David Kleinman, Ravi Vij, Fernando Escalante, Michel Delforge, Nirali Kotowsky, Jacopo Bitetti, Natalie Boytsov, Leena Camadoo-O'Byrne, Lindsey Powers Happ, Guillaume Germain, Ana Urosevic, Malena Mahendran, Mei Sheng Duh, Francois Laliberte, Michele Cavo, Hans C. Lee

https://doi.org/10.3324/haematol.2024.285893

Exposure toxicity of venetoclax in acute myeloid leukemia patients in the real-life setting: impact of high exposure on delayed neutropenia (447 Online Views)

Florent Puisset, Emmanuel Raffoux, Lionel Ades, Tony Huynh, Raphaël Itzykson, Didier Bouscary, Loréa Aguinana, Florence Rabian, Marie Sebert, Anne Vekhoff, Eolia Brissot, Mohamad Mohty, Agnes Bonnin, Alexis Genthon, Jeremie Zerbit, Lise Willems, Justine Decrocq, Adrien Contejean, Etienne Lengline, Samia Mourah, Lauriane Goldwirt

https://doi.org/10.3324/haematol.2024.286062

Eleven cases of laryngeal edema after tisagenlecleucel infusion: a 3-year single center retrospective study of CD19-directed chimeric antigen receptor T-cell therapy for relapsed and refractory B-cell lymphomas (452 Online Views)

Erina Hosoya, Jun Ando, Shintaro Kinoshita, Yoshiki Furukawa, Yuko Toyoshima, Yoko Azusawa, Toru Mitsumori, Eriko Sato, Hina Takano, Yutaka Tsukune, Naoki Watanabe, Tomoiku Takaku, Hajime Yasuda, Yasuharu Hamano, Makoto Sasaki, Shuko Nojiri, Midori Ishii, Miki Ando

https://doi.org/10.3324/haematol.2024.286169

Case Reports

Oct 10, 2024

Editorials
Article

Deep phenotyping of nodal T-cell lymphomas reveals immune alterations and therapeutic targets (691 Online Views)

Pierre Stephan, Jimmy Perrot, Allison Voisin, Maud Barbery, Thibault Andrieu, Maxime Grimont, Julie Caramel, Mathilde Bardou, Garance Tondeur, Edoardo Missiaglia, Philippe Gaulard, François Lemmonier, Laurence de Leval, Emmanuel Bachy, Pierre Sujobert, Laurent Genestier, Alexandra Traverse-Glehen, Yenkel Grinberg-Bleyer

https://doi.org/10.3324/haematol.2023.284448

Articles

Long-term survival can be achieved in a significant fraction of older patients with core binding factor acute myeloid leukemia treated with intensive chemotherapy (671 Online Views)

Federico Mosna, Erika Borlenghi, Mark Litzow, John C. Byrd, Cristina Papayannidis, Cristina Tecchio, Felicetto Ferrara, Guido Marcucci, Roberto Cairoli, Elizabeth A. Morgan, Carmela Gurrieri, Cecilia C.S. Yeung, H. Joachim Deeg, Debora Capelli, Anna Candoni, Jason R. Gotlib, Monia Lunghi, Sheeja Pullarkat, Francesco Lanza, Sara Galimberti, Fabio Forghieri, Adriano Venditti, Moreno Festuccia, Ernesta Audisio, Denise Marvalle, Gian Matteo Rigolin, Giovanni Roti, Eros DiBona, Giuseppe Visani, Francesco Albano, Ann-Kathrin Eisfeld, Peter Valent, Gerwin Huls, Gautam Borthakur, Mauro Krampera, Giovanni Martinelli, Nicolaus Kröger, Alessandra Sperotto, Michele Gottardi

https://doi.org/10.3324/haematol.2024.285448

Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses (502 Online Views)

Jana Trifinopoulos, Julia List, Thorsten Klampfl, Klara Klein, Michaela Prchal-Murphy, Agnieszka Witalisz-Siepracka, Florian Bellutti, Luca L. Fava, Gerwin Heller, Sarah Stummer, Patricia Testori, Monique L. den Boer, Judith M. Boer, Sonja Marinovic, Gregor Hoermann, Wencke Walter, Andreas Villunger, Piotr Sicinski, Veronika Sexl, Dagmar Gotthardt

https://doi.org/10.3324/haematol.2024.285701

CODOX-M/IVAC-R versus DA-EPOCH-R in double hit/triple hit lymphoma patients aged 60 years or under (497 Online Views)

Suheil Albert Atallah-Yunes, Matthew J. Rees, Thomas E. Witzig, Thomas M. Habermann, Javier Munoz, Madiha Iqbal, Ellen D. McPhail, Grzegorz S. Nowakowski

https://doi.org/10.3324/haematol.2024.286168

Letters to the Editor

Expression levels of genes implicated in the working mechanism of lenalidomide predict treatment response in lower risk myelodysplastic syndrome patients (263 Online Views)

Florentien E.M. in’t Hout, Thessa N. Scheele, Theresia M. Westers, Canan Alhan, Carolien Duetz, Eline M.P. Cremers, Heleen A. Visser-Wisselaar, Annelies Verbrugge, Dana A. Chitu, Bert A. van der Reijden, Aniek O. de Graaf, Arjan A. van de Loosdrecht, Joop H. Jansen

https://doi.org/10.3324/haematol.2024.286157

Oct 3, 2024

Perspective Articles

Articles

Pirtobrutinib monotherapy in Bruton tyrosine kinase inhibitor-intolerant patients with B-cell malignancies: results of the phase I/II BRUIN trial (1338 Online Views)

Nirav N. Shah, Michael Wang, Lindsey E. Roeker, Krish Patel, Jennifer A. Woyach, William G. Wierda, Chaitra S. Ujjani, Toby A. Eyre, Pier Luigi Zinzani, Alvaro J. Alencar, Paolo Ghia, Nicole Lamanna, Marc S. Hoffmann, Manish R. Patel, Ian Flinn, James N. Gerson, Shuo Ma, Catherine C. Coombs, Chan Y. Cheah, Ewa Lech-Maranda, Bita Fakhri, Won Seog Kim, Minal A. Barve, Jonathon B. Cohen, Wojciech Jurczak, Talha Munir, Meghan C. Thompson, Donald E. Tsai, Katherine Bao, Nicholas A. Cangemi, Jennifer F. Kherani, Richard A. Walgren, Hongmei Han, Amy S. Ruppert, Jennifer R. Brown

https://doi.org/10.3324/haematol.2024.285754

Outcome of adult acute myeloid leukemia patients with extramedullary disease and treatment with venetoclax/hypomethylating agents (462 Online Views)

Sabine Kayser, Khaled Sanber, Giovanni Marconi, Agnese Mattei, Marlise R. Luskin, Amar Kelkar, Marco Cerrano, Daniel Tuyet Kristensen, Anne Stidsholt Roug, Chiara Sartor, Fabio Giglio, Marta Riva, Lorenzo Rizzo, Francesco Saraceni, Selene Guerzoni, Federica Lessi, Erika Borlenghi, Mark J. Levis, Richard F. Schlenk, Tania Jain, Cristina Papayannidis

https://doi.org/10.3324/haematol.2024.285985

Letters to the Editor

Epigenetic age acceleration in hematopoietic stem cell transplantation (317 Online Views)

Margherita Ursi, Katarzyna Malgorzata Kwiatkowska, Chiara Pirazzini, Gianluca Storci, Daria Messelodi, Salvatore Nicola Bertuccio, Serena De Matteis, Francesco Iannotta, Enrica Tomassini, Marcello Roberto, Maria Naddeo, Noemi Laprovitera, Irene Salamon, Barbara Sinigaglia, Elisa Dan, Francesco De Felice, Francesco Barbato, Enrico Maffini, Sadia Falcioni, Mario Arpinati, Manuela Ferracin, Massimiliano Bonafè, Paolo Garagnani, Francesca Bonifazi

https://doi.org/10.3324/haematol.2024.285291

Temporal changes in erythroid progenitors in critically ill patients: a prospective cohort study (193 Online Views)

Caroline Scott, Isabella Dale-Harris, Andrew E. Armitage, Alexandra E Preston, Simon J. Stanworth, Timothy James, Stuart R. McKechnie, Peter A. Robbins, Hal Drakesmith, Noemi B.A. Roy, Akshay Shah

https://doi.org/10.3324/haematol.2024.285530

Evaluating serum free light chain ratio as a biomarker in multiple myeloma (445 Online Views)

Theresia Akhlaghi, Kylee Maclachlan, Neha Korde, Sham Mailankody, Alexander Lesokhin, Hani Hassoun, Sydney X. Lu, Dhwani Patel, Urvi Shah, Carlyn Tan, Andriy Derkach, Oscar Lahoud, Heather J. Landau, Gunjan L. Shah, Michael Scordo, David J. Chung, Sergio A. Giralt, Saad Z. Usmani, Ola Landgren, Malin Hultcrantz

https://doi.org/10.3324/haematol.2024.285531

Single-cell analysis of the T-cell receptor repertoire in untreated myeloma patients suggests potential myeloma-reactive CD8+ T-cells are shared between blood and marrow (245 Online Views)

James Favaloro, Christian E. Bryant, Edward Abadir, Samuel Gardiner, Shihong Yang, Tracy King, Najah Nassif, Bronwyn A. O’Brien, Lisa M. Sedger, Richard Boyle, Douglas E. Joshua, P. Joy Ho

https://doi.org/10.3324/haematol.2024.285952

Sep 26, 2024

Articles

Letters to the Editor

Safety and efficacy of human amniotic epithelial stem cell eye drops in ocular chronic graft-versus-host disease (214 Online Views)

Xianjing Cheng, Wei Fan, Ruihao Huang, Yuancheng Zhao, Yonghong Tang, Shiqin Huang, Guanghui Zhang, Xi Zhang, Rongdi Yuan, Xiaoqi Wang

https://doi.org/10.3324/haematol.2023.284571

BET inhibitors down-regulate the expression of the essential lncRNA SMILO in multiple myeloma through regulation of the transcription factor FLI1 (276 Online Views)

Nahia Gómez-Echarte, Edurne San José-Enériz, Arantxa Carrasco-León, Naroa Barrena, Estibaliz Miranda, Leire Garate, Beatriz García-Torre, Sandra Alonso-Moreno, Naroa Gimenez-Camino, Estibaliz Urizar-Compains, Danel Olaverri-Mendizabal, Paula Aguirre-Ruiz, Beñat Ariceta, Luis-Esteban Tamariz-Amador, Paula Rodriguez-Otero, Francisco J. Planes, Laura Belver, José Ignacio Martín-Subero, Felipe Prosper, Xabier Agirre

https://doi.org/10.3324/haematol.2024.285966

Sep 19, 2024

Letters to the Editor

Susceptibility to BK polyomavirus-associated hemorrhagic cystitis in children undergoing allogeneic transplant (183 Online Views)

Sheyar Abdullah, Anthony Sabulski, Zahra Hudda, Assem Ziady, Nathan Luebbering, Lucy Giordullo, Elizabeth Odegard, Jason T. Blackard, Steve Kleiboeker, Michelle Altrich, Sonata Jodele, Alix E. Seif, Stella M. Davies, Benjamin L. Laskin

https://doi.org/10.3324/haematol.2024.286163

Comments

Sep 12, 2024

Editorials
Letter to the Editor

Rituximab maintenance after bendamustine-based treatment for follicular lymphoma and mantle cell lymphoma may exert a negative influence on SARS-CoV-2 infection outcomes (726 Online Views)

Ángel Serna, Víctor Navarro, Gloria Iacoboni, Laia López, Juan-Manuel Sancho, Eva González-Barca, Alberto López-García, Raúl Córdoba, Adolfo Sáez, Ana Jiménez Ubieto, Ainara Ferrero, Tomás García, Ángela Sánchez, Cristina García, Marc Bosch, Alba Cabirta, Moraima Jiménez, Ana Marín-Niebla, Francesc Bosch, Pau Abrisqueta

https://doi.org/10.3324/haematol.2024.285219

Articles

Immune reconstitution dynamics after unrelated allogeneic transplantation with post-transplant cyclophosphamide compared to classical immunosuppression with anti-thymocyte globulin: a prospective cohort study (479 Online Views)

Mariana Nassif Kerbauy, Fernanda Agostini Rocha, Leonardo Javier Arcuri, Priscila Silva Cunegundes, Lucila Nassif Kerbauy, Clarisse Martins Machado, Andreza Alice Feitosa Ribeiro, Pinaki P. Banerjee, Luciana Cavalheiro Marti, Nelson Hamerschlak

https://doi.org/10.3324/haematol.2024.285921

Letters to the Editor

Intra-marrow delivery of human interleukin-6-loaded biodegradable microspheres promotes growth of patient-derived multiple myeloma cells in mice (268 Online Views)

Manpreet Bariana, Weiwei Wang, Zhuozhuo Yin, Jingyu Sun, Shabnam Samimi, Shaina A. Anuncio, Elena Cassella, Nuo Xu, Wei Hu, Ariel Aptekmann, David S. Siegel, Kar F. Chow, Hongjun Wang, Johannes L. Zakrzewski

https://doi.org/10.3324/haematol.2024.285980

A phase I study of MAGE-A1-targeted T1367 T-cell receptor-based cell therapy in patients with advanced multiple myeloma (503 Online Views)

Josefine Krüger, Matthias Obenaus, Igor Wolfgang Blau, Dana Hoser, Martin Vaegler, Hana Rauschenbach, Ioannis Anagnostopoulos, Korinna Jöhrens, Vivian Scheuplein, Elisa Kieback, Judith Böhme, Ann-Christin von Brünneck, Jan Krönke, Antonia Busse, Gerald Willimsky, Thomas Blankenstein, Antonio Pezzutto, Ulrich Keller, Axel Nogai

https://doi.org/10.3324/haematol.2024.286124

Sep 5, 2024

Editorials
Article

Outcome of 421 adult patients with Philadelphia-negative acute lymphoblastic leukemia treated under an intensive program inspired by the GIMEMA LAL1913 clinical trial: a Campus ALL study (746 Online Views)

Davide Lazzarotto, Marco Cerrano, Cristina Papayannidis, Sabina Chiaretti, Federico Mosna, Nicola Fracchiolla, Patrizia Zappasodi, Silvia Imbergamo, Maria Ilaria Del Principe, Monia Lunghi, Federico Lussana, Matteo Piccini, Monica Fumagalli, Michelina Dargenio, Prassede Salutari, Fabio Forghieri, Teresa Giulia Da Molin, Massimiliano Bonifacio, Matteo Olivi, Fabio Giglio, Silvia Trappolini, Matteo Leoncin, Antonino Mule, Mario Delia, Crescenza Pasciolla, Francesco Grimaldi, Benedetta Cambo, Lidia Santoro, Fabio Guolo, Paola Minetto, Marzia Defina, Patrizia Chiusolo, Matteo Fanin, Endri Mauro, Lara Aprile, Carla Mazzone, Fabio Trastulli, Maria Ciccone, Marco De Gobbi, Alessandro Cignetti, Eleonora De Bellis, Valentina Mancini, Alfonso Piciocchi, Marco Vignetti, Giovanni Marsili, Irene Della Starza, Renato Fanin, Mario Luppi, Felicetto Ferrara, Giovanni Pizzolo, Renato Bassan, Robin Foa, Anna Candoni

https://doi.org/10.3324/haematol.2024.285638

Articles

Safety and efficacy of acalabrutinib plus bendamustine and rituximab in patients with treatment-naive or relapsed / refractory mantle cell lymphoma: phase Ib trial (668 Online Views)

Tycel Phillips, Michael Wang, Tadeusz Robak, David Gallinson, Don Stevens, Krish Patel, Safaa Ramadan, Chuan-Chuan Wun, Wojciech Jurczak, Stephen D. Smith

https://doi.org/10.3324/haematol.2023.284896

Loncastuximab tesirine in Chinese patients with relapsed or refractory diffuse large B-cell lymphoma: a multicenter, open-label, single-arm, phase II trial (544 Online Views)

Ningjing Lin, Xiuhua Sun, Hui Zhou, Liqun Zou, Keshu Zhou, Lihong Liu, Haiyan Yang, Kai Hu, Qingqing Cai, Yao Liu, Jie Jin, Liling Zhang, Wenyu Li, Ye Guo, Wei Yang, Feng Luo, Zhenguang Wang, Rong Zhu, Lei Yang, Dan Song, Yuqin Song, Jun Zhu

https://doi.org/10.3324/haematol.2024.284973

BCAT1 is a NOTCH1 target and sustains the oncogenic function of NOTCH1 (585 Online Views)

Valeria Tosello, Ludovica Di Martino, Adonia E. Papathanassiu, Silvia Dalla Santa, Marco Pizzi, Lara Mussolin, Jingjing Liu, Pieter van Vlierberghe, Erich Piovan

https://doi.org/10.3324/haematol.2024.285552

Rituximab and lenalidomide for the treatment of relapsed or refractory indolent non-Hodgkin lymphoma: real-life experience (665 Online Views)

Giulio Cassanello, Esther Drill, Alfredo Rivas-Delgado, Michelle Okwali, Irem Isgor, Philip C. Caron, Zachary Epstein-Peterson, Paola Ghione, Paul Hamlin, Jennifer Lue, Steven M. Horwitz, Andrew M. Intlekofer, William Johnson, Anita Kumar, Alison Moskowitz, Ariela Noy, Colette Owens, Lia M. Palomba, Pallawi Torka, Pallavi Galera, Andrew D. Zelenetz, Gilles Salles, Lorenzo Falchi

https://doi.org/10.3324/haematol.2024.285600

Letters to the Editor

Outcomes of patients with primary central nervous system lymphoma following CD19-targeted chimeric antigen receptor T-cell therapy (933 Online Views)

Santiago Mercadal, Kwang Woo Ahn, Mariam Allbee-Johnson, Siddhartha Ganguly, Praveen Ramakrishnan Geethakumari, Sanghee Hong, Adriana Malone, Hemant Murthy, Attaphol Pawarode, Alejandro R. Sica, Melhem Solh, Celalettin Ustun, Mazyar Shadman, Craig S. Sauter, Mehdi Hamadani, Alex F. Herrera, Catherine J. Lee

https://doi.org/10.3324/haematol.2024.285613

Prognostic stratification in venetoclax-based acute myeloid leukemia treatments: the molecular prognostic risk signature tested in a real-world setting (379 Online Views)

Gaia Ciolli, Matteo Piccini, Francesco Mannelli, Giacomo Gianfaldoni, Barbara Scappini, Laura Fasano, Francesca Crupi, Elisa Quinti, Andrea Pasquini, Jessica Caroprese, Giada Rotunno, Fabiana Pancani, Leonardo Signori, Chiara Maccari, Fiorenza I. Vanderwert, Paola Guglielmelli, Alessandro M. Vannucchi

https://doi.org/10.3324/haematol.2024.285934

Adverse prognostic impact of KIT exon 17 mutations despite negative flow cytometric measurable residual disease in pediatric acute myeloid leukemia with RUNX1::RUNX1T1 (534 Online Views)

Shota Kato, Shin-Ichi Tsujimoto, Jun Matsubayashi, Shotaro Iwamoto, Hidefumi Hiramatsu, Yusuke Okuno, Tatsuya Kamitori, Kentaro Ohki, Takao Deguchi, Nobutaka Kiyokawa, Motohiro Kato, Junko Takita, Shiro Tanaka, Souichi Adachi, Daisuke Tomizawa, Norio Shiba

https://doi.org/10.3324/haematol.2024.286243

Aug 29, 2024

Articles

Utilization of allogeneic hematopoietic stem cell transplantation among patients with newly diagnosed acute myeloid leukemia in California: a population-based linked dataset study (323 Online Views)

Christa L. Meyer, Theresa H.M. Keegan, Ann Brunson, Jeffery J. Auletta, Lindsay M. Morton, Ted Wun, Sara J. Schonfeld, Bryan Valcarcel, Renata Abrahão, Rafeek A. Yusuf, Lori Muffly

https://doi.org/10.3324/haematol.2024.285648

T-cell receptor architecture and clonal tiding provide insight into the transformation trajectory of peripheral T-cell lymphomas (545 Online Views)

Edith Willscher, Christoph Schultheiß, Lisa Paschold, Franziska Lea Schümann, Paul Schmidt-Barbo, Benjamin Thiele, Marcus Bauer, Claudia Wickenhauser, Thomas Weber, Mascha Binder

https://doi.org/10.3324/haematol.2024.285395

Letters to the Editor

Characteristics and outcomes associated with CD2 and CD25 expression on bone marrow mast cells in patients with systemic mastocytosis (443 Online Views)

Julien Rossignol, Sophie Georgin-Lavialle, Danielle Canioni, Omer Beganovic, Chantal Brouzes, Olivier Fain, Maël Heiblig, Clément Gourguechon, Philippe Guilpain, Cristina Bulai-Livideanu, Stéphane Barete, Julie Agopian, Fabienne Brenet, Patrice Dubreuil, Richard Lemal, Olivier Tournilhac, Louis Terriou, David Launay, Laurence Bouillet, Catharina Chatain, Ghandi Damaj, Thomas Ballul, Celine Greco, Laura Polivka, Laurent Frenzel, Cécile Meni, Hassiba Bouktit, Dina Benabou, Clotilde Devin, Caroline Gaudy-Marqueste, Marie Gousseff, Edwige Le Mouel, Antoine Neel, Dana Ranta, Roland Jaussaud, Thierry Jo Molina, Julie Bruneau, Rose-Marie Javier, Fabien Pelletier, Florence Castelain, Frederique Retornaz, Quentin Cabrera, Patricia Zunic, Marie Pierre Gourin, Ewa Wierzbicka-Hainaut, Jean François Viallard, Christian Lavigne, Cyrille Hoarau, Isabelle Durieu, Sophie Dimicoli-Salazar, Jose Miguel Torregrosa-Diaz, Audrey Duval, Nicolas Garcelon, Jeremie Lespinasse, Angèle Soria, Yannick Chantran, Michel Arock, Christine Bodemer, Olivier Lortholary, Vahid Asnafi, Olivier Hermine, Ludovic Lhermitte

https://doi.org/10.3324/haematol.2024.285740

Aug 22, 2024

Editorials
Article

Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia (869 Online Views)

Mohd Minhajuddin, Amanda Winters, Haobin Ye, Shanshan Pei, Brett Stevens, Austin Gillen, Krysta Engel, Stephanie Gipson, Monica Ransom, Maria Amaya, Anagha Inguva, Maura Gasparetto, Mark J. Althoff, Regan Miller, Ian Shelton, Hunter Tolison, Anna Krug, Rachel Culp-Hill, Angelo D’Alessandro, Daniel W Sherbenou, Daniel A. Pollyea, Clayton Smith, Craig T Jordan

https://doi.org/10.3324/haematol.2023.284716

Letters to the Editor

Hodgkin/Reed-Sternberg cells induce GPNMB expression and release from macrophages to suppress T-cell responses to the Epstein-Barr virus-encoded LMP2A protein (384 Online Views)

Navta Masand, Tracey A. Perry, Matthew Pugh, Eanna Fennell, Aoife Hennessy, Wenbin Wei, Katerina Bouchalova, David Burns, Pamela Kearns, Graham Taylor, Katerina Vrzalikova, Paul G. Murray

https://doi.org/10.3324/haematol.2024.285319

Comparing the clinical trial efficacy versus real-world effectiveness of treatments for multiple myeloma: a population-based study (521 Online Views)

Alissa Visram, Kelvin Kar-Wing Chan, Hsien Seow, Gregory Pond, Anastasia Gayowsky, Ghulam Rehman Mohyuddin, Arleigh McCurdy, Irwindeep Sandhu, Christopher Venner, Guido Lancman, Amaris Balitsky, Tom Kouroukis, Robert Bruins, Shaji Kumar, Rafael Fonseca, Hira Mian

https://doi.org/10.3324/haematol.2024.285768

Aug 15, 2024

Articles

Outcome of 421 adult patients with Philadelphia-negative acute lymphoblastic leukemia treated under an intensive program inspired by the GIMEMA LAL1913 clinical trial: a Campus ALL study (746 Online Views)

Davide Lazzarotto, Marco Cerrano, Cristina Papayannidis, Sabina Chiaretti, Federico Mosna, Nicola Fracchiolla, Patrizia Zappasodi, Silvia Imbergamo, Maria Ilaria Del Principe, Monia Lunghi, Federico Lussana, Matteo Piccini, Monica Fumagalli, Michelina Dargenio, Prassede Salutari, Fabio Forghieri, Teresa Giulia Da Molin, Massimiliano Bonifacio, Matteo Olivi, Fabio Giglio, Silvia Trappolini, Matteo Leoncin, Antonino Mule, Mario Delia, Crescenza Pasciolla, Francesco Grimaldi, Benedetta Cambo, Lidia Santoro, Fabio Guolo, Paola Minetto, Marzia Defina, Patrizia Chiusolo, Matteo Fanin, Endri Mauro, Lara Aprile, Carla Mazzone, Fabio Trastulli, Maria Ciccone, Marco De Gobbi, Alessandro Cignetti, Eleonora De Bellis, Valentina Mancini, Alfonso Piciocchi, Marco Vignetti, Giovanni Marsili, Irene Della Starza, Renato Fanin, Mario Luppi, Felicetto Ferrara, Giovanni Pizzolo, Renato Bassan, Robin Foa, Anna Candoni

https://doi.org/10.3324/haematol.2024.285638

Letters to the Editor

Cd39 and P2rx7-Wnt signaling enhance blast pathogenicity in an experimental model of acute myeloid leukemia (414 Online Views)

Lili Feng, Haohai Zhang, Changchuin Mao, Paola de Andrade Mello, Dina Stroopinsky, Eva Csizmadia, Jialin Zhou, David Avigan, Jinming Yu, Wenda Gao, Simon C. Robson

https://doi.org/10.3324/haematol.2024.285547

A novel prognostic nomogram based on imaging and molecular parameters for newly diagnosed extranodal natural killer/T-cell lymphoma patients (401 Online Views)

Dezhi Huang, Fu Li, Shijia Lin, Jing Xia, Bangdong Liu, Xinlei Li, Naya Ma, Yishuo Duan, Yunjing Zeng, Sha Zhou, Shuhan Tang, Wenqiu Huang, Lingyi Rao, Li Gao, Qiong Li, Xi Zhang, Jun Rao

https://doi.org/10.3324/haematol.2024.285362

Comments

Aug 8, 2024

Articles

LP-118 is a novel B-cell lymphoma 2 / extra-large inhibitor that demonstrates efficacy in models of venetoclax-resistant chronic lymphocytic leukemia (792 Online Views)

Janani Ravikrishnan, Daisy Y. Diaz-Rohena, Elizabeth Muhowski, Xiaokui Mo, Tzung-Huei Lai, Shrilekha Misra, Charmelle D. Williams, John Sanchez, Andrew Mitchell, Suresh Satpati, Elizabeth Perry, Tierney Kaufman, Chaomei Liu, Arletta Lozanski, Gerard Lozanski, KerryA Rogers, Adam S. Kittai, Seema A. Bhat, Mary C. Collins, Matthew S. Davids, Nitin Jain, William G. Wierda, Rosa Lapalombella, John C. Byrd, Fenlai Tan, Yi Chen, Yu Chen, Yue Shen, Stephen P. Anthony, Jennifer A. Woyach, Deepa Sampath

https://doi.org/10.3324/haematol.2023.284353

Immunoglobulin prophylaxis prevents hospital admissions for fever in pediatric acute lymphoblastic leukemia: results of a multicenter randomized trial (800 Online Views)

Kirsten A. Thus, Hester A. de Groot-Kruseman, Pauline Winkler-Seinstra, Marta Fiocco, Heidi Segers, Cor van den Bos, Inge M. van der Sluis, Wim J.E. Tissing, Margreet A. Veening, Christian Michel Zwaan, Cornelis M. van Tilburg, Rob Pieters, Marc Bierings

https://doi.org/10.3324/haematol.2024.285428

Hematopoietic cell transplantation for older acute myeloid leukemia patients in first complete remission: results of a randomized phase III study (1227 Online Views)

Dietger Niederwieser, Dirk Hasenclever, Wolfgang E. Berdel, Bart J. Biemond, Haifa Al-Ali, Yves Chalandon, Michel van Gelder, Christian Junghanß, Gösta Gahrton, Mathias Hänel, Rüdiger Hehlmann, Thomas Heinicke, Andreas Hochhaus, Simona Iacobelli, Rien van Marwijk Kooy, Nicolaus Kröger, Jeroen Janssen, Madlen Jentzsch, Frank Breywisch, Mohamad Mohty, Stavroula Masouridi-Levrat, Gert Ossenkoppele, Jacob Passweg, Wolfram Pönisch, Johannes Schetelig, Christoph Schliemann, Sebastian Schwind, Matthias Stelljes, Leo F. Verdonck, Vladan Vucinic, Bob Löwenberg, Jan Cornelissen

https://doi.org/10.3324/haematol.2024.285879

Letters to the Editor

Contribution of copy number to improve risk stratification of adult T-cell acute lymphoblastic leukemia patients enrolled in measurable residual disease-oriented trials (347 Online Views)

Celia Gonzalez-Gil, Mireia Morgades, Thaysa Lopes, Francisco Fuster-Tormo, Pau Montesinos, Pere Barba, Marina Diaz-Beya, Lourdes Hermosin, Clara Maluquer, Jose Gonzalez-Campos, Teresa Bernal, Marta Sitges Arriaga, Lurdes Zamora, Marta Pratcorona, Rodrigo Martino, Maria Jose Larrayoz, Teresa Artola, Anna Torrent, Ferran Vall-llovera, Mar Tormo, Cristina Gil, Andres Novo, Pilar Martinez-Sanchez, Jordi Ribera, Maria-Paz Queipo, Teresa Gonzalez-Martinez, Monica Cabrero, Antonia Cladera, Jose Cervera, Alberto Orfao, Josep Maria Ribera, Eulalia Genesca

https://doi.org/10.3324/haematol.2024.285416

Aug 1, 2024

Comments

Jul 25, 2024

Articles

Unlocking the therapeutic potential of selective CDK7 and BRD4 Inhibition against multiple myeloma cell growth (506 Online Views)

Yao Yao, Shuhui Deng, Jessica Fong Ng, Mei Yuan, Chandraditya Chakraborty, Vera JoyWeiler, Nikhil Munshi, Mariateresa Fulciniti

https://doi.org/10.3324/haematol.2024.285491

Letters to the Editor

Increased frequency of clonal hematopoiesis of indeterminate potential in Bloom syndrome probands and carriers (354 Online Views)

Isabella Lin, Angela Wei, Tsumugi A. Gebo, Paul C. Boutros, Maeve Flanagan, Nicole Kucine, Christopher Cunniff, Valerie A. Arboleda, Vivian Y. Chang

https://doi.org/10.3324/haematol.2024.285239

Jul 18, 2024

Articles

Atezolizumab combined with immunogenic salvage chemoimmunotherapy in patients with transformed diffuse large B-cell lymphoma (611 Online Views)

Tamer Othman, Paul Frankel, Pamela Allen, Leslie L. Popplewell, Geoffrey Shouse, Tanya Siddiqi, Alexey V. Danilov, Nora Ruel, Shari Daniels, Lacolle Peters, Stella Khoo, Steven T. Rosen, Elad Sharon, Miguel Villalona-Calero, Christopher Ruel, Joseph Tuscano, Alex F. Herrera

https://doi.org/10.3324/haematol.2024.285185

Risk of infections in multiple myeloma. A population-based study on 8672 multiple myeloma patients diagnosed 2008-2021 from the Swedish Myeloma Registry (631 Online Views)

Cecilie Hveding Blimark, Kristina Carlson, Christopher Day, Sigrun Einarsdottir, Gunnar Juliusson, Moshtak Karma, Dorota Knut-Bojanowska, Gunnar Larfors, Ingemar Turesson, Mariana Villegas-Scivetti, Ingigerdur Sverrisdóttir

https://doi.org/10.3324/haematol.2024.285645

Letters to the Editor

Polytypic B cells, monotypic/monoclonal B-cell proliferations, and neoplastic T cells diverge from TET2-/DNMT3A-mutant clonal hematopoiesis in follicular helper T-cell lymphomas (770 Online Views)

Natasha E. Lewis, Kseniya Petrova-Drus, Rohan Sardana, Sarah Huet, Qi Gao, Shenon Sethi, Chad Vanderbilt, Wenbin Xiao, Mikhail Roshal, Jeeyeon Baik, Himanshu Bhurtel, Alison J. Moskowitz, Steven M. Horwitz, Ahmet Dogan

https://doi.org/10.3324/haematol.2024.285183

Jul 11, 2024

Letters to the Editor

Rituximab maintenance after bendamustine-based treatment for follicular lymphoma and mantle cell lymphoma may exert a negative influence on SARS-CoV-2 infection outcomes (726 Online Views)

Ángel Serna, Víctor Navarro, Gloria Iacoboni, Laia López, Juan-Manuel Sancho, Eva González-Barca, Alberto López-García, Raúl Córdoba, Adolfo Sáez, Ana Jiménez Ubieto, Ainara Ferrero, Tomás García, Ángela Sánchez, Cristina García, Marc Bosch, Alba Cabirta, Moraima Jiménez, Ana Marín-Niebla, Francesc Bosch, Pau Abrisqueta

https://doi.org/10.3324/haematol.2024.285219

Jun 27, 2024

Articles

Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia (869 Online Views)

Mohd Minhajuddin, Amanda Winters, Haobin Ye, Shanshan Pei, Brett Stevens, Austin Gillen, Krysta Engel, Stephanie Gipson, Monica Ransom, Maria Amaya, Anagha Inguva, Maura Gasparetto, Mark J. Althoff, Regan Miller, Ian Shelton, Hunter Tolison, Anna Krug, Rachel Culp-Hill, Angelo D’Alessandro, Daniel W Sherbenou, Daniel A. Pollyea, Clayton Smith, Craig T Jordan

https://doi.org/10.3324/haematol.2023.284716

Letters to the Editor

Respiratory syncytial virus and other vaccine-preventable infections in Multiple Myeloma. A population-based study on 8672 myeloma patients diagnosed 2008-2021 from the Swedish Myeloma Registry (425 Online Views)

Sigrun Einarsdottir, Ingigerdur Sverrisdottir, Mariana Villegas-Scivetti, Chris Day, Ingemar Turesson, Gunnar Juliusson, Markus Hansson, Gunnar Larfors, Cecilie Hveding Blimark

https://doi.org/10.3324/haematol.2024.285161

May 30, 2024

Articles

Deep phenotyping of nodal T-cell lymphomas reveals immune alterations and therapeutic targets (691 Online Views)

Pierre Stephan, Jimmy Perrot, Allison Voisin, Maud Barbery, Thibault Andrieu, Maxime Grimont, Julie Caramel, Mathilde Bardou, Garance Tondeur, Edoardo Missiaglia, Philippe Gaulard, François Lemmonier, Laurence de Leval, Emmanuel Bachy, Pierre Sujobert, Laurent Genestier, Alexandra Traverse-Glehen, Yenkel Grinberg-Bleyer

https://doi.org/10.3324/haematol.2023.284448

Aug 19, 2021

Errata Corrige

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma (3783 Online Views)

Johannes Duell, Kami J. Maddocks, Eva González-Barca, Wojciech Jurczak, Anna Marina Liberati, Sven de Vos, Zsolt Nagy, Aleš Obr, Gianluca Gaidano, Pau Abrisqueta, Nagesh Kalakonda, Marc André, Martin Dreyling, Tobias Menne, Olivier Tournilhac, Marinela Augustin, Andreas Rosenwald, Maren Dirnberger-Hertweck, Johannes Weirather, Sumeet Ambarkhane, Gilles Salles

https://doi.org/10.3324/haematol.2021.279802

May 10, 2018

Articles

GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells (1478 Online Views)

Beibei Zhang, Pilar Ayuda Durán, Laure Piechaczyk, Yngvar Fløisand, Mireia Mayoral Safont Safont, Ida Tveit Karlsen, Zina Fandalyuk, Dagim Tadele, Pepijn van Mierlo, Alexander D. Rowe, Joseph M. Robertson, Bjørn Tore Gjertsen, Emmet McCormack, Jorrit M. Enserink, Bjørn Tore Gjertsen Group, Emmet McCormack Group

https://doi.org/10.3324/haematol.2018.189399