Early view

Nov 24, 2022

Articles

Hyperactive CREB subpopulations increase during therapy in paediatric B lineage acute lymphoblastic leukaemia (46 Online Views)

Dino Masic, Kayleigh Fee, Hayden Bell, Marian Case, Gabby Witherington, Sophie Lansbury, Juan Ojeda-Garcia, David McDonald, Claire Schwab, Frederik W van Delft, Andrew Filby, Julie Anne Elizabeth Irving

https://doi.org/10.3324/haematol.2022.281177

Targeting glutaminase is therapeutically effective in ibrutinib-resistant mantle cell lymphoma (57 Online Views)

Lingzhi Li, Lei Nie, Alexa Jordan, Qingsong Cai, Yang Liu, Yijing Li, Yuxuan Che, Jovanny Vargas, Zhihong Chen, Angela Leeming, Wei Wang, Yixin Yao, Michael Wang, Vivian Changying Jiang

https://doi.org/10.3324/haematol.2022.281538

Letters to the Editor

Landscape of immunoglobulin heavy chain gamma gene class switch recombination in patients with adult T-cell leukemia–lymphoma (50 Online Views)

Hiroaki Hiramatsu, Kisato Nosaka, Shigeru Kusumoto, Nobuaki Nakano, Ilseung Choi, Makoto Yoshimitsu, Yoshitaka Imaizumi, Michihiro Hidaka, Hidenori Sasaki, Junya Makiyama, Eiichi Ohtsuka, Tatsuro Jo, Masao Ogata, Asahi Ito, Kentaro Yonekura, Hiro Tatetsu, Takeharu Kato, Toshiro Kawakita, Youko Suehiro, Kenji Ishitsuka, Shinsuke Iida, Takaji Matsutani, Hiroyoshi Nishikawa, Atae Utsunomiya, Ryuzo Ueda, Takashi Ishida

https://doi.org/10.3324/haematol.2022.281435

Nov 17, 2022

Editorials
Article

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through inhibition of autophagy (498 Online Views)

Weiguo Zhang, Guopan Yu, Hongying Zhang, Mahesh Basyal, Charlie Ly, Bin Yuan, Vivian Ruvolo, Sujan Piya, Seemana Bhattacharya, Qi Zhang, Gautam Borthakur, Venkata Battula, Marina Konopleva, William G. Rice, Michael Andreeff

https://doi.org/10.3324/haematol.2022.280884

Editorials
Letter to the Editor

Age- and gender-matched controls needed for platelet-based biomarker studies (185 Online Views)

Siamack Sabrkhany, Marijke J.E. Kuijpers, Sander M.J. van Kuijk, Arjan W. Griffioen, Mirjam G.A. oude Egbrink

https://doi.org/10.3324/haematol.2022.281726

Review Articles

Animal models of Diamond-Blackfan anemia: updates and challenges (130 Online Views)

Y. Lucy Liu, Aya Shibuya, Bert Glader, Mark C. Wilkes, Maria Barna, Kathleen M. Sakamoto

https://doi.org/10.3324/haematol.2022.282042

Articles

Diffuse large B-cell lymphoma in octogenarians aged 85 and older can benefit from treatment with curative intent: a report on 129 patients prospectively registered in the Elderly Project of the Fondazione Italiana Linfomi (FIL) (118 Online Views)

Alessandra Tucci, Francesco Merli, Alberto Fabbri, Luigi Marcheselli, Chiara Pagani, Benedetta Puccini, Dario Marino, Manuela Zanni, Elsa Pennese, Leonardo Flenghi, Annalisa Arcari, Barbara Botto, Melania Celli, Caterina Mammi, Alessandro Re, Giulia Campostrini, Agostino Tafuri, Vittorio R. Zilioli, Emanuele Cencini, Roberto Sartori, Chiara Bottelli, Michele Merli, Luigi Petrucci, Guido Gini, Monica Balzarotti, Federica Cavallo, Gerardo Musuraca, Stefano Luminari, Giuseppe Rossi, Michele Spina

https://doi.org/10.3324/haematol.2022.281407

Letters to the Editor

Dysfunctional subsets of CD39+ T cells, distinct from PD-1+, driven by leukemic extracellular vesicles in myeloid leukemias (192 Online Views)

Julian Swatler, Domenico Lo Tartaro, Rebecca Borella, Marta Brewinska-Olchowik, Annamaria Paolini, Anita Neroni, Laura Turos-Korgul, Milena Wiech, Ewa Kozlowska, Dominik Cysewski, Wioleta Grabowska-Pyrzewicz, Urszula Wojda, Grzegorz Basak, Rafael J. Argüello, Andrea Cossarizza, Sara De Biasi, Katarzyna Piwocka

https://doi.org/10.3324/haematol.2022.281713

Axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma patients in complete metabolic response (131 Online Views)

Andrew P. Jallouk, Sushanth Gouni, Jason Westin, Lei Feng, Haleigh Mistry, Raphael E Steiner, Jinsu James, Mansoor Noorani, Sandra Horowitz, Nahum Puebla-Osorio, Luis E Fayad, Swaminathan P. Iyer, Misha Hawkins, Christopher R Flowers, Sairah Ahmed, Loretta J Nastoupil, Partow Kebriaei, Elizabeth J Shpall, Sattva S Neelapu, Yago Nieto, Paolo Strati

https://doi.org/10.3324/haematol.2022.281954

Case Reports

Clinical response to dabrafenib and chemotherapy in clonally-related histiocytosis and acute lymphoblastic leukemia (113 Online Views)

Gervaise Hubert, Henrique Bittencourt, Caroline Laverdière, Pierre Teira, Sonia Cellot, Sylvie Langlois, Alexandre Rouette, Thomas Sontag, Daniel Sinnett, Dorothée Dal-Soglio, Sophie Turpin, Thai Hoa Tran

https://doi.org/10.3324/haematol.2022.281926

Nov 10, 2022

Articles

Allogeneic, Off-the-Shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high risk patients (307 Online Views)

Spyridoula Vasileiou, LaQuisa Hill, Manik Kuvalekar, Aster G. Workineh, Ayumi Watanabe, Yovana Velazquez, Suhasini Lulla, Kimberly Mooney, Natalia Lapteva, Bambi J. Grilley, Helen E. Heslop, Cliona M. Rooney, Malcolm K. Brenner, Todd N. Eagar, George Carrum, Kevin A. Grimes, Ann M. Leen, Premal Lulla

https://doi.org/10.3324/haematol.2022.281946

Contribution of fetal microchimeric cells to maternal wound healing in sickle cell ulcers (145 Online Views)

Mansour Alkobtawi, Maria Sbeih, Karim Souaid, Qui Trung Ngô, Dany Nassar, Hugo Arbes, Henri Guillet, Anoosha Habibi, Pablo Bartolucci, Mathieu Castela, Sélim Aractingi, Bénédicte Oulès

https://doi.org/10.3324/haematol.2022.281140

Letters to the Editor

Identification of multiple genetic loci associated with RBC alloimmunization in mice (151 Online Views)

Arijita Jash, Heather L. Howie, Ariel M. Hay, Chance John Luckey, Krystalyn E. Hudson, Peter C. Thomson, Sarah J. Ratcliffe, Mark Smolkin, James C. Zimring

https://doi.org/10.3324/haematol.2022.281767

Longitudinal analysis of the evolution of cellular immunity to SARS-CoV-2 induced by infection and vaccination (136 Online Views)

Spyridoula Vasileiou, Manik Kuvalekar, Yovana Velazquez, Ayumi Watanabe, Mansi Narula, Aster G. Workineh, Matthew French-Kim, Alejandro Torres Chavez, Sarah Gilmore, Cliona M. Rooney, Ann M. Leen

https://doi.org/10.3324/haematol.2022.281947

Perspective Articles

Nov 3, 2022

Articles

B and T cell acute lymphoblastic leukemia evade chemotherapy at distinct sites in the bone marrow (330 Online Views)

Malwine J. Barz, Lena Behrmann, Danaëlle Capron, Gabriele Zuchtriegel, Fabio D. Steffen, Leo Kunz, Yang Zhang, Iria Jimenez Vermeerbergen, Blerim Marovca, Moritz Kirschmann, Antonia Zech, César Nombela-Arrieta, Urs Ziegler, Timm Schroeder, Beat Bornhauser, Jean-Pierre Bourquin

https://doi.org/10.3324/haematol.2021.280451

Genomics improves risk stratification of adults with T-cell acute lymphoblastic leukemia patients enrolled in measurable residual disease-oriented trials (399 Online Views)

Celia González-Gil, Mireia Morgades, Thaysa Lopes, Francisco Fuster-Tormo, Jesús García-Chica, Ran Zhao, Pau Montesinos, Anna Torrent, Marina Diaz-Beya, Rosa Coll, Lourdes Hermosín, Santiago Mercadal, José González-Campos, Lurdes Zamora, Teresa Artola, Ferran Vall-Llovera, Mar Tormo, Cristina Gil-Cortés, Pere Barba, Andrés Novo, Jordi Ribera, Teresa Bernal, Paula López de Ugarriza, María-Paz Queipo, Pilar Martínez-Sánchez, Alicia Giménez, Teresa González-Martínez, Antonia Cladera, José Cervera, Rosa Fernández-Martín, María Ángeles Ardaiz, María Jesús Vidal, Ángela Baena, Nuria López-Bigas, Anna Bigas, Jaroslaw Maciejewski, Alberto Orfao, Josep Maria Ribera, Eulalia Genescà

https://doi.org/10.3324/haematol.2022.281196

An objective assessment in newly diagnosed multiple myeloma to avoid treatment complications and strengthen therapy adherence (149 Online Views)

Maximilian Holler, Gabriele Ihorst, Heike Reinhardt, Amelie Rösner, Magdalena Braun, Mandy-Deborah Möller, Esther Dreyling, Katja Schoeller, Sophia Scheubeck, Ralph Wäsch, Monika Engelhardt

https://doi.org/10.3324/haematol.2022.281489

Letters to the Editor

Delayed hemolytic transfusion reaction in children with sickle cell disease: first five-year retrospective study in mainland France (135 Online Views)

Claire Falguière, Slimane Allali, Bassem Khazem, Annie Kamdem, Cécile Arnaud, Marie Belloy, Corinne Guitton, Marie-Hélène Odièvre, Sophie Pertuisel, Cecile Dumesnil, Cécile Guillaumat, Nathalie Garrec, Alexandra Gauthier, Perrine Mahe, Valerie Soussan-Banini, Laure Le-Carrer, Etienne Merlin, Audrey David, Beatrice Pellegrino, Catherine Paillard, Jean-Francois Brasme, Marie Lagarde, France Pirenne, Corinne Pondarre

https://doi.org/10.3324/haematol.2022.281050

Prognostic impact of pre-treatment immunoglobulin clonal composition in pediatric Blymphoblastic leukemia (133 Online Views)

Carol Fries, Lik Wee Lee, Meenakshi Devidas, Yunfeng Dai, Karen R. Rabin, Sumit Gupta, Mignon L. Loh, Ilan R Kirsch, Brent Wood, Rachel E. Rau

https://doi.org/10.3324/haematol.2022.281146

Unique pathologic features and gene expression signatures distinguish blastoid high-grade B-cell lymphoma from B acute lymphoblastic leukemia/lymphoma (155 Online Views)

Lianqun Qiu, Jie Xu, Pei Lin, Evan N. Cohen, Guilin Tang, Sa A. Wang, Mahsa Khanlari, Wei Wang, Joseph D. Khoury, Sergej Konoplev, C. Cameron Yin, Jeffrey L. Jorgensen, Francisco Vega, L. Jeffrey Medeiros, Shaoying Li

https://doi.org/10.3324/haematol.2022.281646

Oct 27, 2022

Editorials
Article

Improved survival in myeloma patients– a nationwide registry study of 4647 patients ≥75 years treated in Denmark and Sweden (303 Online Views)

Kari Lenita Falck Moore, Ingemar Turesson, Anna Genell, Tobias W. Klausen, Dorota Knut-Bojanowska, Louise Redder, Ingigerdur Sverrisdottir, Jonathan Thorsen, Annette J. Vangsted, Cecilie H. Blimark

https://doi.org/10.3324/haematol.2021.280424

Letters to the Editor

International multicentre retrospective analysis of thiotepa-based autologous stem cell transplantation for secondary central nervous system lymphoma (343 Online Views)

Jahanzaib Khwaja, Amy A. Kirkwood, Lisa K. Isbell, Sara Steffanoni, Harshita Goradia, Lisa Pospiech, Thomas Fail, Emma Nicholson, Kate Fletcher, Kim M. Linton, Katrina E. Parsons, Nagah Elmusharaf, Lydia Eccersley, Toby A. Eyre, Sridhar Chaganti, Jeffrey Smith, Nisha Thakrar, Alexandra Kutilina, Teresa Calimeri, Nicolas Martinez-Calle, Dima El-Sharkawi, Wendy Osborne, Gerald Illerhaus, Christopher P. Fox, Andrés J.M. Ferreri, Elisabeth Schorb, Kate Cwynarski

https://doi.org/10.3324/haematol.2022.281640

Oct 20, 2022

Editorials
Article

Pathology review identifies frequent misdiagnoses in recurrent classic Hodgkin lymphoma in a nation-wide cohort: Implications for clinical and epidemiological studies (267 Online Views)

Max V. Boot, Michael Schaapveld, Esther C. van den Broek, Nathalie J. Hijmering, PALGA Group, Kimberly van der Oord, Flora E. van Leeuwen, Avinash G. Dinmohamed, Lianne Koens, Daphne de Jong

https://doi.org/10.3324/haematol.2022.280840

Review Articles

Articles

Three-year results from phase 1 of ZUMA-4: KTE-X19 in pediatric relapsed/refractory acute lymphoblastic leukemia (497 Online Views)

Alan S. Wayne, Van Huynh, Nobuko Hijiya, Rayne H. Rouce, Patrick A. Brown, Joerg Krueger, Carrie L. Kitko, Edward Dela Ziga, Michelle L. Hermiston, Michael K. Richards, Andre Baruchel, Petra C. Schuberth, John Rossi, Lang Zhou, Lovely Goyal, Rajul Jain, Remus Vezan, Behzad Kharabi Masouleh, Daniel W. Lee

https://doi.org/10.3324/haematol.2022.280678

Treatment patterns and outcomes in relapsed/refractory follicular lymphoma: results from the international SCHOLAR-5 study (467 Online Views)

Paola Ghione, M Lia Palomba, Hervé Ghesquieres, Sabela Bobillo, Anik R Patel, Myrna Nahas, Steve Kanters, Kevin Deighton, Anthony Hatswell, Long Ma, Eve H. Limbrick-Oldfield, Julia Thornton Snider, Sally W. Wade, Maria Teresa Riberio, John Radford, Sara Beygi, John Gribben

https://doi.org/10.3324/haematol.2022.281421

Enhancing regulatory T cell function via inhibition of high mobility group box 1 protein signaling in immune thrombocytopenia (490 Online Views)

Haoyi Wang, Tianshu Yu, Ning An, Yunqi Sun, Pengcheng Xu, Panpan Han, Yajing Zhao, Lingjun Wang, Xiaofei Ni, Yubin Li, Guosheng Li, Yanfeng Liu, Jun Peng, Ming Hou, Yu Hou

https://doi.org/10.3324/haematol.2022.281557

Letters to the Editor

Prognostic value of positron emission tomography/computed tomography in transplanteligible newly diagnosed multiple myeloma patients from CASSIOPEIA: the CASSIOPET study (271 Online Views)

Françoise Kraeber-Bodéré, Sonja Zweegman, Aurore Perrot, Cyrille Hulin, Denis Caillot, Thierry Facon, Xavier Leleu, Karim Belhadj, Emmanuel Itti, Lionel Karlin, Clément Bailly, Mark-David Levin, Monique C. Minnema, Bastien Jamet, Caroline Bodet-Milin, Bart de Keizer, Marie C. Béné, Hervé Avet-Loiseau, Pieter Sonneveld, Lixia Pei, Fabio Rigat, Carla de Boer, Jessica Vermeulen, Tobias Kampfenkel, Jérôme Lambert, Philippe Moreau

https://doi.org/10.3324/haematol.2021.280051

Cytomegalovirus reactivation after CD19 CAR T cell therapy is clinically significant (378 Online Views)

George Chen, Megan Herr, Jan Nowak, Christine Ho, Nikolaos Almyroudis, Kristopher Attwood, John Bonnewell, Marissa Walsh, Brahm Segal, Maureen Ross, Philip McCarthy, Theresa Hahn

https://doi.org/10.3324/haematol.2022.281719

Oct 13, 2022

Editorials
Letter to the Editor

Clonal hematopoiesis by DNMT3A mutations as a common finding in idiopathic splanchnic vein thrombosis (239 Online Views)

Giovanna Carrà, Emilia Giugliano, Sofia Camerlo, Giorgio Rosati, Enrica Branca, Beatrice Maffeo, Isabella Russo, Rocco Piazza, Daniela Cilloni, Alessandro Morotti

https://doi.org/10.3324/haematol.2022.281705

Editorials

Articles

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through inhibition of autophagy (498 Online Views)

Weiguo Zhang, Guopan Yu, Hongying Zhang, Mahesh Basyal, Charlie Ly, Bin Yuan, Vivian Ruvolo, Sujan Piya, Seemana Bhattacharya, Qi Zhang, Gautam Borthakur, Venkata Battula, Marina Konopleva, William G. Rice, Michael Andreeff

https://doi.org/10.3324/haematol.2022.280884

Variation and impact of polygenic hematological traits in monogenic sickle cell disease (376 Online Views)

Thomas Pincez, Ken Sin Lo, Anne-Laure Pham Hung d’Alexandry d’Orengiani, Melanie E. Garrett, Carlo Brugnara, Allison E. Ashley-Koch, Marilyn J. Telen, Frederic Galacteros, Philippe Joly, Pablo Bartolucci, Guillaume Lettre

https://doi.org/10.3324/haematol.2022.281180

A phase Ib trial of mivavotinib (TAK-659), a dual SYK/FLT3 inhibitor, in patients with relapsed/refractory acute myeloid leukemia (256 Online Views)

Keith W. Pratz, Jason Kaplan, Moshe Levy, Dale Bixby, Patrick W. Burke, Harry Erba, Trisha M. Wise-Draper, Gail J. Roboz, Nikolaos Papadantonakis, Trivikram Rajkhowa, Daniela Hernandez, Iwona Dobler, Richard C. Gregory, Cheryl Li, Shining Wang, Kate Stumpo, Karuppiah Kannan, Harry Miao, Mark Levis

https://doi.org/10.3324/haematol.2022.281216

Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation (474 Online Views)

Yvonne J. Thus, Martin F.M. de Rooij, Nathalie Swier, Roderick L. Beijersbergen, Jeroen E.J. Guikema, Marie-José Kersten, Eric Eldering, Steven T. Pals, Arnon P. Kater, Marcel Spaargaren

https://doi.org/10.3324/haematol.2022.281668

Letters to the Editor

Influence of bisphosphonates or recombinant human parathyroid hormone on in vitro chemotherapy sensitivity of acute lymphoblastic leukemia cells (159 Online Views)

Demi T.C. de Winter, Jenneke E. van Atteveld, Jessica G.C.A.M. Buijs-Gladiness, Rob Pieters, Sebastian J.C.M.M. Neggers, Jules P.P. Meijerink, Marry M. van den Heuvel-Eibrink

https://doi.org/10.3324/haematol.2022.281033

Case Reports

Leon's helmet (162 Online Views)

Hugo Gonzalez, Alice Marceau-Renaut, Marc Spentchian, Maen Hassoun, Geoffroy Guignedoux

https://doi.org/10.3324/haematol.2022.281125

Oct 6, 2022

Articles

CD56brightCD16 natural killer cells as an important regulatory mechanism in chronic graft-versus-host disease (528 Online Views)

Madeline Lauener, Shima AzadPour, Sayeh Abdossamadi, Vaishnavi Parthasarathy, Bernard Ng, Elena Ostroumov, Geoffrey D.E. Cuvelier, Megan K. Levings, Katherine N. MacDonald, Amina Kariminia, Kirk R. Schultz

https://doi.org/10.3324/haematol.2022.280653

Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on Cytomegalovirus reactivation risk after allogeneic hematopoietic stem cell transplantation (468 Online Views)

Elena Tassi, Maddalena Noviello, Pantaleo De Simone, Maria T. Lupo-Stanghellini, Matteo Doglio, Francesca Serio, Danilo Abbati, Valeria Beretta, Veronica Valtolina, Giacomo Oliveira, Sara Racca, Edoardo Campodonico, Eliana Ruggiero, Daniela Clerici, Fabio Giglio, Francesca Lorentino, Roee Dvir, Elisabetta Xue, Francesca Farina, Chiara Oltolini, Francesco Manfredi, Luca Vago, Consuelo Corti, Massimo Bernardi, Massimo Clementi, Liselotte Brix, Fabio Ciceri, Jacopo Peccatori, Raffaella Greco, Chiara Bonini

https://doi.org/10.3324/haematol.2022.280685

Oral HDAC inhibitor tucidinostat in patients with relapsed or refractory peripheral T-cell lymphoma: phase IIb results (970 Online Views)

Shinya Rai, Won Seog Kim, Kiyoshi Ando, Ilseung Choi, Koji Izutsu, Norifumi Tsukamoto, Masahiro Yokoyama, Kunihiro Tsukasaki, Junya Kuroda, Jun Ando, Michihiro Hidaka, Youngil Koh, Hirohiko Shibayama, Toshiki Uchida, Deok Hwan Yang, Kenji Ishitsuka, Kenichi Ishizawa, Jin Seok Kim, Hong Ghi Lee, Hironobu Minami, Hyeon Seok Eom, Mitsutoshi Kurosawa, Jae Hoon Lee, Jong Seok Lee, Won Sik Lee, Hirokazu Nagai, Takero Shindo, Dok Hyun Yoon, Shinichiro Yoshida, Mireille Gillings, Hiroshi Onogi, Kensei Tobinai

https://doi.org/10.3324/haematol.2022.280996

Lenalidomide-based triplet regimens in first relapsed multiple myeloma patients: real-world evidence from a propensity score matched analysis (508 Online Views)

Silvia Mangiacavalli, Claudio Salvatore Cartia, Monica Galli, Sara Pezzatti, Angelo Belotti, Francesca Fazio, Roberto Mina, Magda Marcatti, Anna Cafro, Renato Zambello, Laura Paris, Gregorio Barilà, Cecilia Olivares, Alessandra Pompa, Rita Mazza, Francesca Farina, Martina Soldarini, Pietro Benvenuti, Giuseppina Pagani, Michele Palumbo, Valeria Masoni, Virginia Valeria Ferretti, Catherine Klersy, Luca Arcaini, Maria Teresa Petrucci

https://doi.org/10.3324/haematol.2022.281342

Development and manufacturing of novel locally produced anti-BCMA CART cells for the treatment of relapsed/refractory multiple myeloma: phase I clinical results (471 Online Views)

Nathalie Asherie, Shlomit Kfir-Erenfeld, Batia Avni, Miri Assayag, Tatyana Dubnikov, Nomi Zalcman, Eyal Lebel, Eran Zimran, Adir Shaulov, Marjorie Pick, Yael Cohen, Irit Avivi, Cyrille Cohen, Moshe E. Gatt, Sigal Grisariu, Polina Stepensky

https://doi.org/10.3324/haematol.2022.281628

Letters to the Editor

Mutations in the RACGAP1 gene cause autosomal recessive congenital dyserythropoietic anemia type III (246 Online Views)

Gonzalo Hernández, Lídia Romero-Cortadellas, Xènia Ferrer-Cortès, Veronica Venturi, Mercedes Dessy-Rodriguez, Mireia Olivella, Ammar Husami, Concepción Pérez de Soto, Rosario M. Morales-Camacho, Ana Villegas, Fernando-Ataulfo González-Fernández, Marta Morado, Theodosia A. Kalfa, Oscar Quintana-Bustamante, Santiago Pérez-Montero, Cristian Tornador, Jose-Carlos Segovia, Mayka Sánchez

https://doi.org/10.3324/haematol.2022.281277

Impact of daratumumab-based induction on stem cell collection parameters in Swedish myeloma patients (299 Online Views)

Konstantinos Lemonakis, Love Tatting, Mikael Lisak, Kristina Carlson, Jacob Crafoord, Cecilie H Blimark, Antonio I Santamaria, Stina Wichert, Stig Lenhoff, Markus Hansson

https://doi.org/10.3324/haematol.2022.281610

Age- and gender-matched controls needed for platelet-based biomarker studies (185 Online Views)

Siamack Sabrkhany, Marijke J.E. Kuijpers, Sander M.J. van Kuijk, Arjan W. Griffioen, Mirjam G.A. oude Egbrink

https://doi.org/10.3324/haematol.2022.281726

Associations between socio-economic status and bispecific LV20.19 CAR T cell therapy outcomes (232 Online Views)

Jennifer M. Knight, Edward Hackett, Aniko Szabo, Ruizhe Wu, Garrett Sauber, Bryon Johnson, Rachel N. Cusatis, Elizabeth Aughey, Steve W. Cole, Cecilia J. Hillard, Nirav N. Shah

https://doi.org/10.3324/haematol.2022.281957

Comments

Sep 29, 2022

Editorials
Article

Heterogeneity in long term outcomes for R-ISS stage II in newly diagnosed multiple myeloma patients (349 Online Views)

Anais Schavgoulidze, Valerie Lauwers-Cances, Aurore Perrot, Titouan Cazaubiel, Marie-Lorraine Chretien, Philippe Moreau, Thierry Facon, Xavier Leleu, Lionel Karlin, Anne-Marie Stoppa, Olivier Decaux, Karim Belhadj, Bertrand Arnulf, Mohamad Mohty, Clara M ariette, Cecile Fohrer-Sonntag, Pascal Lenain, Jean-Pierre Marolleau, Mourad Tiab, Carla Araujo, Frederique Orsini-Piocelle, Arnaud Jaccard, Murielle Roussel, Lotfi Benboubker, Jean-Richard Eveillard, Mamoun Dib, Marion Divoux, Michel Attal, Herve Avet-Loiseau, Jill Corre

https://doi.org/10.3324/haematol.2021.280566

Articles

Plasminogen activator-coated nanobubbles targeting cell-bound β2-glycoprotein I as a novel thrombus-specific thrombolytic strategy (278 Online Views)

Paolo Macor, Paolo Durigutto, Monica Argenziano, Kate Smith-Jackson, Sara Capolla, Valeria Di Leonardo, Kevin Marchbank, Valerio Stefano Tolva, Fabrizio Semeraro, Concetta T. Ammollo, Mario Colucci, Roberta Cavalli, Pierluigi Meroni, Francesco Tedesco

https://doi.org/10.3324/haematol.2022.281505

Comments

Sep 22, 2022

Articles

Genome-wide CRISPR screens identify ferroptosis as a novel therapeutic vulnerability in acute lymphoblastic leukemia (537 Online Views)

Marie-Eve Lalonde, Marc Sasseville, Anne-Marie Gélinas, Jean-Sébastien Milanese, Kathie Béland, Simon Drouin, Elie Haddad, Richard Marcotte

https://doi.org/10.3324/haematol.2022.280786

Small molecule SUMO inhibition for biomarker-informed B-cell lymphoma therapy (472 Online Views)

Uta M. Demel, Matthias Wirth, Schayan Yousefian, Le Zhang, Konstandina Isaakidis, Judith Dönig, Marlitt Böger, Nikita Singh, Hazal Köse, Simon Haas, Stefan Müller, Markus Schick, Ulrich Keller

https://doi.org/10.3324/haematol.2022.280995

Letters to the Editor

Rituximab therapy after pediatric hematopoietic stem cell transplantation can cause prolonged B cell impairment and increases the risk for infections - a retrospective matched cohort study (248 Online Views)

Michael Launspach, Dennis Temel, Emily Ohlendorf, Felix Zirngibl, Bianca Materne, Lena Oevermann, Hedwig E. Deubzer, Anton G. Henssen, Annette Künkele, Patrick Hundsdörfer, Horst von Bernuth, Axel Pruß, Angelika Eggert, Arend von Stackelberg, Peter Lang, Johannes H. Schulte

https://doi.org/10.3324/haematol.2022.281134

Von Willebrand factor in the plasma and in the tumor tissue predicts cancerassociated thrombosis and mortality (254 Online Views)

Ioannis Karampinis, Kai Nowak, Julian Koett, Christian Mess, Laura Wagner, Timo Gaiser, Frank Thomas Mayer, Lukas Goertz, Stefan Werner Schneider, Alexander Thomas Bauer

https://doi.org/10.3324/haematol.2022.281315

Donor cell-derived myelofibrosis relapse after allogeneic stem cell transplantation (246 Online Views)

Patrizia Chiusolo, Nicoletta Orlando, Sabrina Giammarco, Monica Rossi, Elisabetta Metafuni, Salvatore Leotta, Giuseppe Milone, Caterina Giovanna Valentini, Maria Bianchi, Filippo Frioni, Claudio Pellegrino, Federica Sorà, Luigi Maria Larocca, Simona Sica, Andrea Bacigalupo, Luciana Teofili

https://doi.org/10.3324/haematol.2022.281564

Contribution of measurable residual disease status to prediction accuracy of relapse and survival in adults with acute myeloid leukemia undergoing allogeneic hematopoietic cell transplantation (301 Online Views)

Eduardo Rodríguez-Arbolí, Megan Othus, Corentin Orvain, Lucas C. Zarling, Brenda M. Sandmaier, Filippo Milano, Gary Schoch, Chris Davis, H. Joachim Deeg, Frederick R. Appelbaum, Rainer Storb, Roland B. Walter

https://doi.org/10.3324/haematol.2022.281631

Sep 15, 2022

Letters to the Editor

Clinical impact of clonal hematopoiesis on severe COVID-19 patients without canonical risk factors (380 Online Views)

Chang Kyung Kang, Baekgyu Choi, Sugyeong Kim, Choong Hyun Sun, Soon Ho Yoon, Kyukwang Kim, Euijin Chang, Jongtak Jung, Pyoeng Gyun Choe, Wan Beom Park, Eu Suk Kim, Hong Bin Kim, Nam Joong Kim, Myoung-don Oh, Hogune Im, Joohae Kim, Yong Hoon Lee, Jaehee Lee, Hyonho Chun, Youngil Koh, Ji Yeon Lee, Joon Ho Moon, Kyoung-Ho Song, Inkyung Jung

https://doi.org/10.3324/haematol.2022.280621

Mitigation of gastrointestinal graft versus host disease with tocilizumab prophylaxis is accompanied by preservation of microbial diversity and attenuation of enterococcal domination (683 Online Views)

Saurabh Chhabra, Aniko Szabo, Annelie Clurman, Katelynn McShane, Nicholas Waters, Daniel Eastwood, Lisa Samanas, Teng Fei, Gabriel Armijo, Sameen Abedin, Walter Longo, Parameswaran Hari, Mehdi Hamadani, Nirav N. Shah, Lyndsey Runaas, James H. Jerkins, Marcel van den Brink, Jonathan U. Peled, William R. Drobyski

https://doi.org/10.3324/haematol.2022.281309

Sep 8, 2022

Articles

Targeting dual oncogenic machineries driven by TAL1 and PI3K-AKT pathways in T-cell acute lymphoblastic leukemia (389 Online Views)

Fang Qi Lim, Allison Si-Yu Chan, Rui Yokomori, Xiao Zi Huang, Madelaine Skolastika Theardy, Allen Eng Juh Yeoh, Shi Hao Tan, Takaomi Sanda

https://doi.org/10.3324/haematol.2022.280761

Activation of lncRNA NEAT1 leads to survival advantage of multiple myeloma cells by supporting a positive regulatory loop with DNA repair proteins (521 Online Views)

Elisa Taiana, Cecilia Bandini, Vanessa Katia Favasuli, Domenica Ronchetti, Ilaria Silvestris, Noemi Puccio, Katia Todoerti, Silvia Erratico, Domenica Giannandrea, Niccolò Bolli, Nicola Amodio, Alessia Ciarrocchi, Raffaella Chiaramonte, Yvan Torrente, Roberto Piva, Antonino Neri

https://doi.org/10.3324/haematol.2022.281167

Letters to the Editor

Treatment patterns and clinical outcomes of asciminib in a real-world multi-resistant chronic myeloid leukemia patient population (514 Online Views)

Camille C.B. Kockerols, Jeroen J.W.M Janssen, Nicole M.A. Blijlevens, Saskia K. Klein, Laura G.M. van Hussen-Daenen, Gwendolyn G.Y. van Gorkom, Willem M. Smit, Peter van Balen, Bart J. Biemond, Marjan J. Cruijsen, Maarten F. Corsten, Peter A.W. te Boekhorst, Harry R. Koene, Geerte L. van Sluis, Jan J. Cornelissen, Peter E. Westerweel

https://doi.org/10.3324/haematol.2022.281386

Adverse karyotype subcategories in acute myeloid leukemia display significant differences in mutation composition and transplant-augmented survival (276 Online Views)

Ayalew Tefferi, Amritpal Singh, Naseema Gangat, Aref Al-Kali, Hassan Alkhateeb, Mithun Shah, Mrinal S. Patnaik, Michelle A. Elliott, William J. Hogan, Mark R. Litzow, Alexandra Wolanskyj-Spinner, Christopher C. Hook, Abhishek Mangaonkar, David Viswanatha, Dong Chen, Animesh Pardanani, Kebede H. Begna, Rhett P. Ketterling

https://doi.org/10.3324/haematol.2022.281495

Sep 1, 2022

Articles

ATRA works synergistically with the γ-secretase inhibitor crenigacestat to augment BCMA on multiple myeloma and the efficacy of BCMA-CAR T-cells (381 Online Views)

Estefanía García-Guerrero, Luis G. Rodríguez-Lobato, Belén Sierro-Martínez, Sophia Danhof, Stephan Bates, Silke Frenz, Larissa Härtle, Ralph Götz, Markus Sauer, Leo Rasche, K. Martin Kortüm, Jose A. Pérez-Simón, Hermann Einsele, Michael Hudecek, Sabrina R. Prommersberger

https://doi.org/10.3324/haematol.2022.281339

Aug 25, 2022

Editorials
Article

ASXL1 mutations accelerate bone marrow fibrosis via EGR1-TNFA axis mediated neoplastic fibrocyte generation in myeloproliferative neoplasms (464 Online Views)

Zhongxun Shi, Jinqin Liu, Yingying Zhao, Lin Yang, Yanan Cai, Peihong Zhang, Zefeng Xu, Tiejun Qin, Shiqiang Qu, Lijuan Pan, Junying Wu, Xin Yan, Zexing Li, Wenjun Zhang, Yiru Yan, Huijun Huang, Gang Huang, Bing Li, Xudong Wu, Zhijian Xiao

https://doi.org/10.3324/haematol.2021.280320

Editorials
Article

Characterization of therapy-related acute myeloid leukemia: increasing incidence and prognostic implications (719 Online Views)

Christer Nilsson, Fredrika Linde, Erik Hulegårdh, Hege Garelius, Vladimir Lazarevic, Petar Antunovic, Jörg Cammenga, Stefan Deneberg, Anna Eriksson, Martin Jädersten, Cecilia Kämpe Björkvall, Lars Möllgård, Lovisa Wennström, Emma Ölander, Martin Höglund, Gunnar Juliusson, Sören Lehmann

https://doi.org/10.3324/haematol.2022.281233

Editorials
Article

Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia (691 Online Views)

Binay K. Sahoo, Yuh-Charn Lin, Cheng-Fen Tu, Chien-Chin Lin, Wei-Ju Liao, Fu-An Li, Ling-Hui Li, Kurt Yun Mou, Steve R. Roffler, Shu-Ping Wang, Chi-Tai Yeh, Chi-Yuan Yao, Hsin-An Hou, Wen-Chien Chou, Hwei-Fang Tien, Ruey-Bing Yang

https://doi.org/10.3324/haematol.2022.281151

Articles

Serum vascular endothelial growth factor is associated with cardiovascular involvement and response to therapy in Erdheim-Chester disease (345 Online Views)

Anais Roeser, Marine Bravetti, Lida Dong, Levi-Dan Azoulay, Frederic Charlotte, Makoto Miyara, Pascale Ghillani-Dalbin, Jean-Francois Emile, Fadwa El Kouari, Hamza Ouni, Jean-Marc Lacorte, Isabelle Brocheriou, Zahir Amoura, Fleur Cohen-Aubart, Julien Haroche

https://doi.org/10.3324/haematol.2022.280755

BCL6 inhibition ameliorates ruxolitinib resistance in CRLF2-rearranged acute lymphoblastic leukemia (477 Online Views)

Shinobu Tsuzuki, Takahiko Yasuda, Hiroaki Goto, Naoko Maeda, Koshi Akahane, Takeshi Inukai, Hideyuki Yamamoto, Sivasundaram Karnan, Akinobu Ota, Toshinori Hyodo, Hiroyuki Konishi, Yoshitaka Hosokawa, Hitoshi Kiyoi, Fumihiko Hayakawa

https://doi.org/10.3324/haematol.2022.280879

Letters to the Editor

Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization (505 Online Views)

Fiona E. Reed, Nicole M. Eskow, Elizabeth Min, Maximillian Carlino, Rubia Mancuso, Nayoung Kwon, Elenoe C. Smith, Shannon T. Larsuel, Lin Wang, Vanessa Scanlon, Diane S. Krause

https://doi.org/10.3324/haematol.2021.280499

αβT- and B-cell-depleted HLA-haploidentical hematopoietic stem cell transplantation in children with myelodysplastic syndromes (322 Online Views)

Pietro Merli, Daria Pagliara, Tommaso Mina, Valentina Bertaina, Giuseppina Li Pira, Stefania Lazzaro, Simone Biagini, Federica Galaverna, Luisa Strocchio, Roberto Carta, Maria Luigia Catanoso, Francesco Quagliarella, Marco Becilli, Emilia Boccieri, Francesca Del Bufalo, Arianna Panigari, Annalisa Agostini, Lucia Pedace, Simone Pizzi, Cesare Perotti, Mattia Algeri, Marco Zecca, Franco Locatelli

https://doi.org/10.3324/haematol.2022.280698

Investigational venetoclax combination therapy in acute myeloid leukemia – a systematic review and meta-analysis (206 Online Views)

Shai Shimony, Alon Rozental, Jan P. Bewersdorf, Aaron D. Goldberg, Eytan M. Stein, Alyssa A. Grimshaw, Richard M. Stone, Daniel J. DeAngelo, Ofir Wolach, Maximilian Stahl

https://doi.org/10.3324/haematol.2022.281453

Under-representation of ethnic minorities in early phase clinical trials for multiple myeloma (277 Online Views)

Samir Asher, Aikaterini Kazantzi, Fatjon Dekaj, Luke Steventon, Aisha Khatun, Louise Ainley, Annabel McMillan, Neil Rabin, Ashu Wechalekar, Jonathan Sive, Charalampia Kyriakou, Xenofon Papanikolaou, Ke Xu, Shameem Mahmood, Brendan Wisniowski, Lydia Lee, Kwee Yong, Rakesh Popat

https://doi.org/10.3324/haematol.2022.281322

Aug 18, 2022

Articles

High transferrin saturation predicts inferior clinical outcomes in patients with MDS (431 Online Views)

Jennifer Teichman, Michelle Geddes, Nancy Zhu, Mary-Margaret Keating, Mitchell Sabloff, Grace Christou, Brian Leber, Dina Khalaf, Eve St-Hilaire, Nicholas Finn, April Shamy, Karen W.L. Yee, John M. Storring, Thomas J. Nevill, Robert Delage, Mohamed Elemary, Versha Banerji, Brett Houston, Lee Mozessohn, Lisa Chodirker, Liying Zhang, Mohammed Siddiqui, Anne Parmentier, Heather A. Leitch, Rena J. Buckstein

https://doi.org/10.3324/haematol.2022.280723

Selective inhibition of MCL1 overcomes venetoclax-resistance in a murine model of myelodysplastic syndromes (658 Online Views)

Melissa A. Fischer, Yuanbin Song, Maria P. Arrate, Rana Gbyli, Matthew T. Villaume, Brianna N. Smith, Merrida A. Childress, Thomas P. Stricker, Stephanie Halene, Michael R. Savona

https://doi.org/10.3324/haematol.2022.280631

In vivo stabilization of a less toxic asparaginase variant leads to a durable anti-tumor response in acute leukemia (420 Online Views)

Maaike Van Trimpont, Amanda M. Schalk, Yanti De Visser, Hien Anh Nguyen, Lindy Reunes, Katrien Vandemeulebroecke, Evelien Peeters, Ying Su, Hyun Lee, Philip L. Lorenzi, Wai-Kin Chan, Veerle Mondelaers, Barbara De Moerloose, Tim Lammens, Steven Goossens, Pieter Van Vlierberghe, Arnon Lavie

https://doi.org/10.3324/haematol.2022.281390

Letters to the Editor

Circulating endothelial cells and the study of vascular injury in children undergoing hematopoietic stem cell transplant (297 Online Views)

Anthony Sabulski, Sheyar Abdullah, Nathan Luebbering, Benjamin Aunins, Caitlin Castillo, Kelly Lake, Alexandra Duell, Lauren Strecker, Lucille Giordullo, William Broomhead, Scott Dimeo, Elizabeth A. Odegard, Jason T. Blackard, Assem Ziady, Alix E. Seif, Christopher E. Dandoy, Benjamin L. Laskin, Sonata Jodele, Stella M. Davies

https://doi.org/10.3324/haematol.2022.280788

Hematological Historical Vignette

Aug 11, 2022

Articles

Osteoprogenitor SFRP1 prevents exhaustion of hematopoietic stem cells via PP2A-PR72/130-mediated regulation of p300 (484 Online Views)

Franziska Hettler, Christina Schreck, Sandra Romero Marquez, Thomas Engleitner, Baiba Vilne, Theresa Landspersky, Heike Weidner, Renate Hausinger, Ritu Mishra, Rupert Oellinger, Martina Rauner, Ronald Naumann, Christian Peschel, Florian Bassermann, Roland Rad, Rouzanna Istvanffy, Robert A.J. Oostendorp

https://doi.org/10.3324/haematol.2022.280760

Molecular monitoring of T-cell kinetics and migration in severe neurotoxicity after real-world CD19-specific chimeric antigen receptor-T cell therapy (1379 Online Views)

Susanna Carolina Berger, Boris Fehse, Nuray Akyüz, Maria Geffken, Christine Wolschke, Dietlinde Janson, Nico Gagelmann, Marlene Luther, Dominic Wichmann, Christian Frenzel, Guenther Thayssen, Anna Alegiani, Anita Badbaran, Silke Zeschke, Judith Dierlamm, Nicolaus Kröger, Francis A. Ayuk

https://doi.org/10.3324/haematol.2022.281110

Potent preclinical activity of FLT3-directed chimeric antigen receptor T cell immunotherapy against FLT3-mutant acute myeloid leukemia and KMT2A-rearranged acute lymphoblastic leukemia (1047 Online Views)

Lisa M. Niswander, Zachary T. Graff, Christopher D. Chien, John A. Chukinas, Christina A. Meadows, Lillie C. Leach, Joseph P. Loftus, M. Eric Kohler, Sarah K. Tasian, Terry J. Fry

https://doi.org/10.3324/haematol.2022.281456

Case Reports

Aug 4, 2022

Editorials
Letter to the Editor

Morbidity and mortality of sickle cell disease patients is unaffected by splenectomy: evidence from 3 decades follow-up in a high-income setting (284 Online Views)

Valeria Maria Pinto, Barbara Gianesin, Frédéric B. Piel, Filomena Longo, Paolo Rigano, Alessandra Quota, Vincenzo Spadola, Giovanna Graziadei, Filippo Mazzi, Maria Domenica Cappellini, Aurelio Maggio, Antonio Piga, Lucia De Franceschi, Gian Luca Forni

https://doi.org/10.3324/haematol.2022.280815

Articles

Early expression of CD94 and loss of CD96 on CD8+ T cells after allogeneic SCT is predictive of subsequent relapse and survival (561 Online Views)

Kriti Verma, Wayne Croft, Hayden Pearce, Jianmin Zuo, Christine Stephens, Jane Nunnick, Francesca AM Kinsella, Ram Malladi, Paul Moss

https://doi.org/10.3324/haematol.2021.280497

Clinical and biological impact of ATP-binding cassette transporter activity in adult acute myeloid leukemia (384 Online Views)

Elise Sourdeau, Ludovic Suner, Mara Memoli, Alexis Genthon, Frédéric Feger, Lou Soret, Nasséra Abermil, Laurence Heuberger, Chrystele Bilhou-Nabera, Hélène Guermouche, Fabrizia Favale, Simona Lapusan, Michael Chaquin, Claire Hirschauer, Mohamad Mohty, Ollivier Legrand, François Delhommeau, Pierre Hirsch

https://doi.org/10.3324/haematol.2022.280676

Translational readthrough at F8 nonsense variants in factor VIII B domain contributes to residual expression and lowers inhibitor association (371 Online Views)

Maria Francesca Testa, Silvia Lombardi, Francesco Bernardi, Mattia Ferrarese, Donata Belvini, Paolo Radossi, Giancarlo Castaman, Mirko Pinotti, Alessio Branchini

https://doi.org/10.3324/haematol.2022.281279

Letters to the Editor

Onset of blast crisis in chronic myeloid leukemia patients in treatment-free remission (612 Online Views)

Stephanie Dulucq, Sandrine Hayette, Jean-Michel Cayuela, Frédéric Bauduer, Kaddour Chabane, Patrice Chevallier, Pascale Cony-Makhoul, Pascale Flandrin-Gresta, Caroline Le Jeune, Yannick Le Bris, Laurence Legros, Hervé Maisonneuve, Lydia Roy, Francois-Xavier Mahon, Ivan Sloma, Delphine Rea, Franck Emmanuel Nicolini

https://doi.org/10.3324/haematol.2022.280740

Case Reports

Mass spectrometry-based proteomics in clinical practice amyloid typing: state-of-the-art from a French nationwide cohort (391 Online Views)

Magali Colombat, Margot Gaspard, Mylène Camus, Jessica Dalloux-Chioccioli, Audrey Delas, Elsa Poullot, Anissa Moktefi, Arnaud François, Anne Moreau, Jean-Bapiste Gibier, Pierre Raynaud, Antoine Huart, Alexis Piedrafita, Julia Gilhodes, Olivier Lairez, Gilles Grateau, Sophie Georgin-Lavialle, Hervé Maisonneuve, Philippe Moreau, Arnaud Jaccard, Franck Bridoux, Violaine Plante-Bordeneuve, Thibaud Damy, Hervé Mal, Pierre Brousset, Sophie Valleix, Odile Burlet-Schiltz

https://doi.org/10.3324/haematol.2022.281431

Jul 28, 2022

Editorials
Article

Improving the anti-acute myeloid leukemia activity of CD123-specific Engager T cells by MyD88 and CD40 costimulation (1262 Online Views)

Abishek Vaidya, Erin Doherty, Xiya Wu, Sujuan Huang, Nikhil Hebbar, Unmesha Thanekar, Challice L. Bonifant, Cheng Cheng, Stephen Gottschalk, M. Paulina Velasquez

https://doi.org/10.3324/haematol.2021.279301

Review Articles

Articles

Analysis of rare driving events in pediatric acute myeloid leukemia (593 Online Views)

Sanne Noort, Jolieke van Oosterwijk, Jing Ma, Elizabeth A.R. Garfinkle, Stephanie Nance, Michael Walsh, Guangchun Song, Dirk Reinhardt, Martina Pigazzi, Franco Locatelli, Henrik Hasle, Jonas Abrahamsson, Marie Jarosova, Charikleia Kelaidi, Sophia Polychronopoulou, Marry M. van den Heuvel-Eibrink, Maarten Fornerod, Tanja A. Gruber, C. Michel Zwaan

https://doi.org/10.3324/haematol.2021.280250

Case Reports

Acute myeloid leukemia early after anti-CD19 chimeric antigen receptor T cells infusion in a patient with refractory diffuse large B cell lymphoma and pre-existing clonal hematopoiesis (542 Online Views)

Lorenza Falini, Alessandra Venanzi, Valentina Tini, Alessandra Innocente, Stelvio Ballanti, Simonetta Saldi, Silvio Sivolella, Antonio Pierini, Cynthia Aristei, Enrico Tiacci, Vincenzo Maria Perriello, Brunangelo Falini

https://doi.org/10.3324/haematol.2022.281351

Jul 21, 2022

Editorials
Article

Hypercortisolemic Cushing's patients possess a distinct class of hematopoietic progenitor cells leading to erythrocytosis (555 Online Views)

Lilian Varricchio, Eliza B Geer, Fabrizio Martelli, Maria Mazzarini, Alister Funnell, James J Bieker, Thalia Papayannopoulou, Anna Rita Migliaccio

https://doi.org/10.3324/haematol.2021.280542

Editorials
Article

Time spent at home among older adults with acute myeloid leukemia receiving azacitidine- or venetoclax-based regimens (621 Online Views)

Christopher E. Jensen, Hilary M. Heiling, Konan E. Beke, Allison M. Deal, Ashley L. Bryant, Lorinda A. Coombs, Matthew C. Foster, Daniel R. Richardson

https://doi.org/10.3324/haematol.2022.280728

Jul 14, 2022

Editorials

Articles

RHOA regulated IGFBP2 promotes invasion and drives progression of BCR-ABL1 chronic myeloid leukemia (752 Online Views)

Hualei Zhang, Baohuan Cai, Yun Liu, Yating Chong, Atsuko Matsunaga, Stephanie Fay Mori, Xuexiu Fang, Eiko Kitamura, Chang-Sheng Chang, Ping Wang, John K Cowell, Tianxiang Hu

https://doi.org/10.3324/haematol.2022.280757

Allogeneic transplant following CAR T-cell therapy for large B-cell lymphoma (1661 Online Views)

Joanna Zurko, Jeremy Ramdial, Mazyar Shadman, Sairah Ahmed, Aniko Szabo, Lorenzo Iovino, Ana Alarcon Tomas, Craig Sauter, Miguel-Angel Perales, Nirav. N. Shah, Utkarsh H. Acharya, Caron Jacobson, Robert J. Soiffer, Trent Wang, Krishna V. Komanduri, Samantha Jaglowski, Adam S. Kittai, Nathan Denlinger, Madiha Iqbal, Mohamed A. Kharfan-Dabaja, Ernesto Ayala, Julio Chavez, Michael Jain, Frederick L. Locke, Yazeed Samara, Lihua E. Budde, Matthew G. Mei, Alexandra Della Pia, Tatyana Feldman, Nausheen Ahmed, Ryan Jacobs, Nilanjan Ghosh, Bhagirathbhai Dholaria, Olalekan O. Oluwole, Brian Hess, Ayesha Hassan, Vaishalee P. Kenkre, Patrick Reagan, Farrukh Awan, Yago Nieto, Mehdi Hamadani, Alex F. Herrera

https://doi.org/10.3324/haematol.2022.281242

Jul 7, 2022

Articles

Comparative analysis of oral and intravenous iron therapy in rat models of inflammatory anemia and iron deficiency (1020 Online Views)

Lara Valente de Souza, Alexander Hoffmann, Christine Fischer, Verena Petzer, Malte Asshoff, Igor Theurl, Piotr Tymoszuk, Markus Seifert, Natascha Brigo, Richard Hilbe, Egon Demetz, Laura Von Raffay, Sylvia Berger, Marina Barros-Pinkelnig, Guenter Weiss

https://doi.org/10.3324/haematol.2022.281149

Jun 30, 2022

Editorials
Article

Comparison of autologous and allogeneic hematopoietic cell transplantation strategies in patients with primary plasma cell leukemia, with dynamic prediction modelling (803 Online Views)

Sarah Lawless, Simona Iacobelli, Nina Simone Knelange, Patrice Chevallier, Didier Blaise, Noel Milpied, Roberto Foà, Jan J. Cornelissen, Bruno Lioure, Ruben Benjamin, Xavier Poiré, Monique C. Minnema, Matthew Collin, Stig Lenhoff, John A. Snowden, Stella Santarone, Keith M. O. Wilson, Fernanda Trigo, Peter Dreger, Lara H. Böhmer, Hein Putter, Laurent Garderet, Nicolaus Kröger, Ibrahim Yaukoub-Agha, Stefan Schönland, Curly Morris

https://doi.org/10.3324/haematol.2021.280568

Editorials

Articles

Comparison of autologous and allogeneic hematopoietic cell transplantation strategies in patients with primary plasma cell leukemia, with dynamic prediction modelling (803 Online Views)

Sarah Lawless, Simona Iacobelli, Nina Simone Knelange, Patrice Chevallier, Didier Blaise, Noel Milpied, Roberto Foà, Jan J. Cornelissen, Bruno Lioure, Ruben Benjamin, Xavier Poiré, Monique C. Minnema, Matthew Collin, Stig Lenhoff, John A. Snowden, Stella Santarone, Keith M. O. Wilson, Fernanda Trigo, Peter Dreger, Lara H. Böhmer, Hein Putter, Laurent Garderet, Nicolaus Kröger, Ibrahim Yaukoub-Agha, Stefan Schönland, Curly Morris

https://doi.org/10.3324/haematol.2021.280568

Combination elotuzumab and lenalidomide treatment efficacy is dependent on crosstalk between NK cells, monocytes and myeloma cells (679 Online Views)

Kelden Richardson, Simon P. Keam, Joe Jiang Zhu, Deborah Meyran, Criselle D’Souza, Sean Macdonald, Kerry Campbell, Michael Robbins, Natalie A. Bezman, Kirsten Todd, Hang Quach, David S. Ritchie, Simon J. Harrison, H. Miles Prince, Joseph A. Trapani, Misty R. Jenkins, Paul A. Beavis, Phillip K. Darcy, Paul J. Neeson

https://doi.org/10.3324/haematol.2021.279930

Axicabtagene ciloleucel compared to tisagenlecleucel for the treatment of aggressive B-cell lymphoma (2230 Online Views)

Mi Kwon, Gloria Iacoboni, Juan Luis Reguera, Lucía López Corral, Rafael Hernani Morales, Valentín Ortiz-Maldonado, Manuel Guerreiro, Ana Carolina Caballero, María Luisa Guerra Domínguez, Jose Maria Sanchez Pina, Alberto Mussetti, Juan Manuel Sancho, Mariana Bastos-Oreiro, Eva Catala, Javier Delgado, Hugo Luzardo Henriquez, Jaime Sanz, María Calbacho, Rebeca Bailén, Cecilia Carpio, Jose Maria Ribera, Anna Sureda, Javier Briones, Juan Carlos Hernandez-Boluda, Nuria Martínez Cebrián, Jose Luis Diez Martin, Alejandro Martín, Pere Barba

https://doi.org/10.3324/haematol.2022.280805

Clinical features of hepatitis E infections in patients with hematologic disorders (441 Online Views)

Susanne Ghandili, Cecilia Lindhauer, Sven Pischke, Julian Schulze zur Wiesch, Philipp H. von Kroge, Susanne Polywka, Carsten Bokemeyer, Walter Fiedler, Nicolaus Kröger, Francis Ayuk, Raissa Adjallé, Franziska Modemann

https://doi.org/10.3324/haematol.2022.280853

Jun 23, 2022

Editorials
Article

STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of BCL2 and BCLXL following glucocorticoid treatment (570 Online Views)

Jordy C.G. van der Zwet, Valentina Cordo’, Jessica G.C.A.M. Buijs-Gladdines, Rico Hagelaar, Willem K. Smits, Eric Vroegindeweij, Laura T.M. Graus, Vera Poort, Marloes Nulle, Rob Pieters, Jules P.P. Meijerink

https://doi.org/10.3324/haematol.2021.280405

Articles

Impaired immunosuppressive role of myeloid-derived suppressor cells in acquired aplastic anemia (779 Online Views)

Peiyuan Dong, Lingyun Chen, Hongfei Wu, Jiali Huo, Zhongxing Jiang, Yingqi Shao, Xiang Ren, Jinbo Huang, Xingxin Li, Min Wang, Neng Nie, Jing Zhang, Peng Jin, Yizhou Zheng, Meili Ge

https://doi.org/10.3324/haematol.2021.280292

In-depth characterization of intratumoral heterogeneity in refractory B-cell non-Hodgkin lymphoma through the lens of a Research Autopsy Program (417 Online Views)

Keren Isaev, Ting Liu, Mehran Bakhtiari, Kit Tong, Rashmi Goswami, Bernard Lam, Ilinca Lungu, Paul M. Krzyzanowski, Amit Oza, Neesha Dhani, Anca Prica, Michael Crump, Robert Kridel

https://doi.org/10.3324/haematol.2022.280900

Jun 16, 2022

Editorials
Article

Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning (1089 Online Views)

Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina M. Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang E. Berdel, Wolfgang Hiddemann, Frank Kroschinsky, Johannes Schetelig, Uwe Platzbecker, Carsten Müller-Tidow, Tim Sauer, Hubert Serve, Claudia Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan Krause, Mathias Hänel, Christoph Schliemann, Maher Hanoun, Christian Thiede, Martin Bornhäuser, Karsten Wendt, Jan Moritz Middeke

https://doi.org/10.3324/haematol.2021.280027

Articles

Monomorphic epitheliotropic intestinal T-cell lymphoma comprises morphologic and genomic heterogeneity impacting outcome (799 Online Views)

Luis Veloza, Doriane Cavalieri, Edoardo Missiaglia, Albane Ledoux-Pilon, Bettina Bisig, Bruno Pereira, Christophe Bonnet, Elsa Poullot, Leticia Quintanilla-Martinez, Romain Dubois, Francisco Llamas-Gutierrez, Céline Bossard, Roland De Wind, Fanny Drieux, Juliette Fontaine, Marie Parrens, Jeremy Sandrini, Virginie Fataccioli, Marie-Hélène Delfau-Larue, Adrien Daniel, Faustine Lhomme, Lauriane Clément-Filliatre, François Lemonnier, Anne Cairoli, Pierre Morel, Sylvie Glaisner, Bertrand Joly, Abderrazak El Yamani, Kamel Laribi, Emmanuel Bachy, Reiner Siebert, David Vallois, Philippe Gaulard, Olivier Tournilhac, Laurence de Leval

https://doi.org/10.3324/haematol.2022.281226

Jun 9, 2022

Articles

PET-imaging assessment for guiding strategy in patients with relapsed/refractory large B-cell lymphoma receiving CAR T-cells (662 Online Views)

Jean Galtier, Laetitia Vercellino, Loic Chartier, Pierre Olivier, Claire Tabouret-Viaud, Charles Mesguich, Roberta Di Blasi, Amandine Durand, Léo Raffy, François-Xavier Gros, Isabelle Madelaine, Veronique Meignin, Miryam Mebarki, Marie-Thérèse Rubio, Pierre Feugier, Olivier Casasnovas, Michel Meignan, Catherine Thieblemont

https://doi.org/10.3324/haematol.2021.280550

Characteristics and outcome of patients with acute myeloid leukemia and trisomy 4 (603 Online Views)

Sabine Kayser, David Martínez-Cuadrón, Maher Hanoun, Friedrich Stölzel, Cristina Gil, H. Christian Reinhardt, Eliana Aguiar, Kerstin Schäfer-Eckart, Juan Miguel Bergua Burgues, Björn Steffen, Teresa Bernal, Stefan W. Krause, Rosalía Riaza, Christoph Schliemann, Jose Cervera, Martin Kaufmann, Laura Torres-Miñana, Mathias Hänel, Evelyn Acuña-Cruz, Edgar Jost, Jesus Lorenzo Algarra, Martina Crysandt, Lars Fransecky, Javier Cornago-Navascues, Sabrina Kraus, Joaquin Martinez-Lopez, Hermann Einsele, Dirk Niemann, Andreas Neubauer, Ruth Seggewiß-Bernhardt, Sebastian Scholl, Stefan A. Klein, Christoph Schmid, Markus Schaich, Martin Schmidt-Hieber, Sven Zukunft, Anthony D. Ho, Uwe Platzbecker, Claudia D. Baldus, Carsten Müller-Tidow, Christian Thiede, Martin Bornhäuser, Hubert Serve, Mark Levis, Pau Montesinos, Christoph Röllig, Richard F. Schlenk

https://doi.org/10.3324/haematol.2022.281137

May 31, 2022

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Article

APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis (807 Online Views)

Simon Stritt, Paquita Nurden, Alan T. Nurden, Jean-François Schved, Jean-Claude Bordet, Maguelonne Roux, Marie-Christine Alessi, David-Alexandre Trégouët, Taija Mäkinen, Muriel Giansily-Blaizot

https://doi.org/10.3324/haematol.2022.280816

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High-risk stage IIB Hodgkin lymphoma treated in the H10 and AHL2011 trials: total metabolic tumor volume is a useful risk factor to stratify patients at baseline (584 Online Views)

Cédric Rossi, Marc André, Jehan Dupuis, Franck Morschhauser, Bertrand Joly, Julien Lazarovici, Hervé Ghesquières, Aspasia Stamatoullas, Emmanuelle Nicolas-Virelizier, Pierre Feugier, Anne-Claire Gac, Hannah Moatti, Luc-Matthieu Fornecker, Bénédicte Deau, Clémentine Joubert, Catherine Fortpied, John Raemaekers, Massimo Federico, Salim Kanoun, Michel Meignan, Alexandra Traverse-Glehen, Anne-Ségolène Cottereau, René-Olivier Casasnova

https://doi.org/10.3324/haematol.2021.280004

May 26, 2022

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Article

Durable discontinuation of systemic therapy in patients affected by chronic graft-versus-host disease (1272 Online Views)

George L. Chen, Lynn Onstad, Paul J. Martin, Paul Carpenter, Joseph Pidala, Sally Arai, Corey Cutler, Betty K. Hamilton, Stephanie J. Lee, Mukta Arora

https://doi.org/10.3324/haematol.2021.279814

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Article

Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease (528 Online Views)

Iryna A. Khasabova, Jacob Gable, Malcolm Johns, Sergey G. Khasabov, Alexander E. Kalyuzhny, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, Virginia S. Seybold, Donald A. Simone

https://doi.org/10.3324/haematol.2021.280460

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Regulation of human T-cell leukemia virus type 1 antisense promoter by myocyte enhancer factor-2C in the context of adult T-cell leukemia and lymphoma (649 Online Views)

Kiran K. Madugula, Julie Joseph, Catherine DeMarino, Rashida Ginwala, Vanessa Teixeira, Zafar K. Khan, Dominic Sales, Sydney Wilson, Fatah Kashanchi, Amanda W. Rushing, Isabelle Lemasson, Edward W. Harhaj, Murali Janakiram, B. Hilda Ye, Pooja Jain

https://doi.org/10.3324/haematol.2021.279542

Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells (641 Online Views)

Sarah Warsi, Maria Dahl, Emma M. K. Smith, Anna Rydstrom, Els Mansell, Valgardur Sigurdsson, Julia Sjoberg, Shamit Soneji, Emma Rorby, Kavitha Siva, Tan H. M. Grahn, Yang Liu, Ulrika Blank, Goran Karlsson, Stefan Karlsson

https://doi.org/10.3324/haematol.2021.279799

Comparable long-term outcomes between upfront haploidentical and identical sibling donor transplant in aplastic anemia: a national registry-based study (1204 Online Views)

Zheng-Li Xu, Lan-Ping Xu, De-Pei Wu, Shun-Qing Wang, Xi Zhang, Rui Xi, Su-Jun Gao, Ling-Hui Xia, Jian-Min Yang, Ming Jiang, Xin Wang, Qi-Fa Liu, Jia Chen, Ming Zhou, Xiao-Jun Huang

https://doi.org/10.3324/haematol.2022.280758

Kinetics of early and late molecular recurrences after first-line imatinib cessation in chronic myeloid leukemia: updated results from the STIM2 trial (519 Online Views)

Stéphanie Dulucq, Franck E. Nicolini, Delphine Rea, Pascale Cony-Makhoul, Aude Charbonnier, Martine Escoffre-Barbe, Valérie Coiteux, Pascal Lenain, Françoise Rigal-Huguet, Jixing Liu, Agnès Guerci-Bresler, Laurence Legros, Jean-Christophe Ianotto, Martine Gardembas, Pascal Turlure, Viviane Dubruille, Philippe Rousselot, Juliana Martiniuc, Henry Jardel, Hyacinthe Johnson-Ansah, Bertrand Joly, Tawfiq Henni, Emilie Cayssials, Patricia Zunic, Marc G. Berger, Bruno Villemagne, Fanny Robbesyn, Stephane Morisset, François-Xavier Mahon, Gabriel Etienne

https://doi.org/10.3324/haematol.2022.280811

May 19, 2022

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Article

Impact of PET-CT status on progression-free survival for relapsed follicular lymphoma patients undergoing autologous stem cell transplant (675 Online Views)

Toby A. Eyre, Sally F. Barrington, Jessica Okosun, Clementina Abamba, Rachel M. Pearce, Julia Lee, Ben Carpenter, Charles R. Crawley, Adrian J.C. Bloor, Maria Gilleece, Emma Nicholson, Nimish Shah, Kim Orchard, Ram Malladi, William M. Townsend

https://doi.org/10.3324/haematol.2021.280287

May 12, 2022

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Letter to the Editor

Integrating biological HLA-DPB1 mismatch models to predict survival after unrelated hematopoietic cell transplantation (627 Online Views)

Annalisa Ruggeri, Liesbeth C. de Wreede, Carlheinz R. Müller, Pietro Crivello, Edouard F. Bonneville, Effie W. Petersdorf, Gerard Socié, Valérie Dubois, Riitta Niittyvuopio, Juha Peräsaari, Ibrahim Yakoub-Agha, Jan J. Cornelissen, Lotte Wieten, Tobias Gedde-Dahl, Edouard Forcade, Charles R. Crawley, Steven G.E. Marsh, Virginie Gandemer, Eleni Tholouli, Claude-Eric Bulabois, Anne Huynh, Goda Choi, Eric Deconinck, Maija Itäla-Remes, Stig Lenhoff, Mats Bengtsson, Jan-Erik Johansson, Gwendolyn van Gorkom, Jorinde D. Hoogenboom, Luca Vago, Vanderson Rocha, Chiara Bonini, Christian Chabannon, Katharina Fleischhauer

https://doi.org/10.3324/haematol.2021.280055

Articles

COVID-19 in adult acute myeloid leukemia patients: a long-term followup study from the European Hematology Association survey (EPICOVIDEHA) (1432 Online Views)

Francesco Marchesi, Jon Salmanton-García, Ziad Emarah, Klára Piukovics, Marcio Nucci, Alberto López-García, Zdeněk Ráčil, Francesca Farina, Marina Popova, Sofia Zompi, Ernesta Audisio, Marie-Pierre Ledoux, Luisa Verga, Barbora Weinbergerová, Tomas Szotkovski, Maria Gomes Da Silva, Nicola Fracchiolla, Nick De Jonge, Graham Collins, Monia Marchetti, Gabriele Magliano, Carolina García-Vidal, Monika M. Biernat, Jaap Van Doesum, Marina Machado, Fatih Demirkan, Murtadha Al-Khabori, Pavel Žák, Benjamín Víšek, Igor Stoma, Gustavo-Adolfo Méndez, Johan Maertens, Nina Khanna, Ildefonso Espigado, Giulia Dragonetti, Luana Fianchi, Maria Ilaria Del Principe, Alba Cabirta, Irati Ormazabal-Vélez, Ozren Jaksic, Caterina Buquicchio, Valentina Bonuomo, Josip Batinić, Ali S. Omrani, Sylvain Lamure, Olimpia Finizio, Noemí Fernández, Iker Falces-Romero, Ola Blennow, Rui Bergantim, Natasha Ali, Sein Win, Jens Van Praet, Maria Chiara Tisi, Ayten Shirinova, Martin Schönlein, Juergen Prattes, Monica Piedimonte, Verena Petzer, Milan Navrátil, Austin Kulasekararaj, Pavel Jindra, Jiří Sramek, Andreas Glenthøj, Rita Fazzi, Cristina De Ramón-Sánchez, Chiara Cattaneo, Maria Calbacho, Nathan C. Bahr, Shaimaa El-Ashwah, Raul Cordoba, Michaela Hanakova, Giovanni Zambrotta, Mariarita Sciumè, Stephen Booth, Raquel Nunes Rodrigues, Maria Vittoria Sacchi, Nicole García-Poutón, Juan-Alberto Martín-González, Sofya Khostelidi, Stefanie Gräfe, Laman Rahimli, Emanuele Ammatuna, Alessandro Busca, Paolo Corradini, Martin Hoenigl, Nikolai Klimko, Philipp Koehler, Antonio Pagliuca, Francesco Passamonti, Oliver A. Cornely, Livio Pagano

https://doi.org/10.3324/haematol.2022.280847

Apr 28, 2022

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Article

Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B cell lymphomas (881 Online Views)

Cristina Lopez, Nikolai Schleussner, Stephan H. Bernhart, Kortine Kleinheinz, Stephanie Sungalee, Henrike L. Sczakiel, Helene Kretzmer, Umut H. Toprak, Selina Glaser, Rabea Wagener, Ole Ammerpohl, Susanne Bens, Maciej Giefing, Juan C. Gonzalez Sanchez, Gordana Apic, Daniel Hubschmann, Martin Janz, Markus Kreuz, Anja Mottok, Judith M. Muller, Julian Seufert, Steve Hoffmann, Jan O. Korbel, Robert B. Russell, Roland Schule, Lorenz Trumper, Wolfram Klapper, Bernhard Radlwimmer, Peter Lichter, Ralf Kuppers, Matthias Schlesner, Stephan Mathas, Reiner Siebert

https://doi.org/10.3324/haematol.2021.280005

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Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement (1061 Online Views)

Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. de Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell

https://doi.org/10.3324/haematol.2021.280557

Apr 21, 2022

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Article

The mutational landscape in chronic myelomonocytic leukemia and its impact on allogeneic hematopoietic cell transplantation outcomes: a Center for Blood and Marrow Transplantation Research (CIBMTR) analysis (1642 Online Views)

Matthew Mei, Raju Pillai, Soyoung Kim, Noel Estrada-Merly, Michelle Afkhami, Lixin Yang, Zhuo Meng, Muhammad Bilal Abid, Mahmoud Aljurf, Ulrike Bacher, Amer Beitinjaneh, Christopher Bredeson, Jean-Yves Cahn, Jan Cerny, Edward Copelan, Corey Cutler, Zachariah DeFilipp, Miguel Angel Diaz Perez, Nosha Farhadfar, César O. Freytes, Shahinaz M. Gadalla, Siddhartha Ganguly, Robert Peter Gale, Usama Gergis, Michael R. Grunwald, Betty K. Hamilton, Shahrukh Hashmi, Gerhard C. Hildebrandt, Hillard M. Lazarus, Mark Litzow, Reinhold Munker, Hemant S. Murthy, Sunita Nathan, Taiga Nishihori, Sagar S. Patel, David Rizzieri, Sachiko Seo, Mithun Vinod Shah, Melhem Solh, Leo F. Verdonck, Ravi Vij, Ronald M. Sobecks, Betul Oran, Bart L. Scott, Wael Saber, Ryotaro Nakamura

https://doi.org/10.3324/haematol.2021.280203

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Letter to the Editor

Crosstalk between β-catenin and WT1 signalling activity in acute myeloid leukemia (787 Online Views)

Megan Wagstaff, Olga Tsaponina, Gilian Caalim, Hayley Greenfield, Leanne Milton-Harris, Erika J Mancini, Allison Blair, Kate J Heesom, Alex Tonks, Richard L Darley, Stefan G Roberts, Rhys G Morgan

https://doi.org/10.3324/haematol.2021.280294

Apr 14, 2022

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Mar 17, 2022

Editorials
Article

Clinical relevance of an objective flow cytometry approach based on limit of detection and limit of quantification for measurable residual disease assessment in acute myeloid leukemia. A post-hoc analysis of the GIMEMA AML1310 trial (727 Online Views)

Francesco Buccisano, Raffaele Palmieri, Alfonso Piciocchi, Valentina Arena, Luca Maurillo, Maria-Ilaria Del Principe, Giovangiacinto Paterno, Maria-Antonietta Irno-Consalvo, Tiziana Ottone, Mariadomenica Divona, Consuelo Conti, Daniela Fraboni, Serena Lavorgna, William Arcese, Maria Teresa Voso, Adriano Venditti

https://doi.org/10.3324/haematol.2021.279777

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Mar 10, 2022

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Article

The IL32/BAFF axis supports prosurvival dialogs in the lymphoma ecosystem and is disrupted by NIK inhibition (865 Online Views)

Salomé Decombis, Antonin Papin, Céline Bellanger, Clara Sortais, Christelle Dousset, Yannick Le Bris, Thiphanie Riveron, Stéphanie Blandin, Philippe Hulin, Benoit Tessoulin, Mathieu Rouel, Steven Le Gouill, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck, David Chiron

https://doi.org/10.3324/haematol.2021.279800

Jan 13, 2022

Articles

Oncogenic TYK2P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade (1063 Online Views)

Katharina Woess, Sabine Macho-Maschler, Dorette S. van Ingen Schenau, Miriam Butler, Caroline Lassnig, Daniel Valcanover, Andrea Poelzl, Katrin Meissl, Barbara Maurer, Tania Brandstoetter, Claus Vogl, Anna Koren, Stefan Kubicek, Anna Orlova, Richard Moriggl, Birgit Strobl, Veronika Sexl, Frank N. van Leeuwen, Roland P. Kuiper, Mathias Mueller

https://doi.org/10.3324/haematol.2021.279848

Aug 19, 2021

Errata Corrige

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma (2421 Online Views)

Johannes Duell, Kami J. Maddocks, Eva González-Barca, Wojciech Jurczak, Anna Marina Liberati, Sven de Vos, Zsolt Nagy, Aleš Obr, Gianluca Gaidano, Pau Abrisqueta, Nagesh Kalakonda, Marc André, Martin Dreyling, Tobias Menne, Olivier Tournilhac, Marinela Augustin, Andreas Rosenwald, Maren Dirnberger-Hertweck, Johannes Weirather, Sumeet Ambarkhane, Gilles Salles

https://doi.org/10.3324/haematol.2021.279802

Aug 5, 2021

Articles

Thymosin β4 is essential for thrombus formation by controlling the G-actin/F-actin equilibrium in platelets (1362 Online Views)

Inga Scheller, Sarah Beck, Vanessa Göb, Carina Gross, Raluca A. I. Neagoe, Katja Aurbach, Markus Bender, David Stegner, Zoltan Nagy, Bernhard Nieswandt

https://doi.org/10.3324/haematol.2021.278537

May 10, 2018

Articles

GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells (967 Online Views)

Beibei Zhang, Pilar Ayuda Durán, Laure Piechaczyk, Yngvar Fløisand, Mireia Mayoral Safont Safont, Ida Tveit Karlsen, Zina Fandalyuk, Dagim Tadele, Pepijn van Mierlo, Alexander D. Rowe, Joseph M. Robertson, Bjørn Tore Gjertsen, Emmet McCormack, Jorrit M. Enserink, Bjørn Tore Gjertsen Group, Emmet McCormack Group

https://doi.org/10.3324/haematol.2018.189399