Early view

Sep 12, 2024

Editorials
Letter to the Editor

Rituximab maintenance after bendamustine-based treatment for follicular lymphoma and mantle cell lymphoma may exert a negative influence on SARS-CoV-2 infection outcomes (435 Online Views)

Ángel Serna, Víctor Navarro, Gloria Iacoboni, Laia López, Juan-Manuel Sancho, Eva González-Barca, Alberto López-García, Raúl Córdoba, Adolfo Sáez, Ana Jiménez Ubieto, Ainara Ferrero, Tomás García, Ángela Sánchez, Cristina García, Marc Bosch, Alba Cabirta, Moraima Jiménez, Ana Marín-Niebla, Francesc Bosch, Pau Abrisqueta

https://doi.org/10.3324/haematol.2024.285219

Articles

Immune reconstitution dynamics after unrelated allogeneic transplantation with post-transplant cyclophosphamide compared to classical immunosuppression with anti-thymocyte globulin: a prospective cohort study (75 Online Views)

Mariana Nassif Kerbauy, Fernanda Agostini Rocha, Leonardo Javier Arcuri, Priscila Silva Cunegundes, Lucila Nassif Kerbauy, Clarisse Martins Machado, Andreza Alice Feitosa Ribeiro, Pinaki P. Banerjee, Luciana Cavalheiro Marti, Nelson Hamerschlak

https://doi.org/10.3324/haematol.2024.285921

Letters to the Editor

Intra-marrow delivery of human interleukin-6-loaded biodegradable microspheres promotes growth of patient-derived multiple myeloma cells in mice (52 Online Views)

Manpreet Bariana, Weiwei Wang, Zhuozhuo Yin, Jingyu Sun, Shabnam Samimi, Shaina A. Anuncio, Elena Cassella, Nuo Xu, Wei Hu, Ariel Aptekmann, David S. Siegel, Kar F. Chow, Hongjun Wang, Johannes L. Zakrzewski

https://doi.org/10.3324/haematol.2024.285980

A phase I study of MAGE-A1-targeted T1367 T-cell receptor-based cell therapy in patients with advanced multiple myeloma (131 Online Views)

Josefine Krüger, Matthias Obenaus, Igor Wolfgang Blau, Dana Hoser, Martin Vaegler, Hana Rauschenbach, Ioannis Anagnostopoulos, Korinna Jöhrens, Vivian Scheuplein, Elisa Kieback, Judith Böhme, Ann-Christin von Brünneck, Jan Krönke, Antonia Busse, Gerald Willimsky, Thomas Blankenstein, Antonio Pezzutto, Ulrich Keller, Axel Nogai

https://doi.org/10.3324/haematol.2024.286124

Sep 5, 2024

Editorials
Article

Outcome of 421 adult patients with Philadelphia-negative acute lymphoblastic leukemia treated under an intensive program inspired by the GIMEMA LAL1913 clinical trial: a Campus ALL study (335 Online Views)

Davide Lazzarotto, Marco Cerrano, Cristina Papayannidis, Sabina Chiaretti, Federico Mosna, Nicola Fracchiolla, Patrizia Zappasodi, Silvia Imbergamo, Maria Ilaria Del Principe, Monia Lunghi, Federico Lussana, Matteo Piccini, Monica Fumagalli, Michelina Dargenio, Prassede Salutari, Fabio Forghieri, Teresa Giulia Da Molin, Massimiliano Bonifacio, Matteo Olivi, Fabio Giglio, Silvia Trappolini, Matteo Leoncin, Antonino Mule, Mario Delia, Crescenza Pasciolla, Francesco Grimaldi, Benedetta Cambo, Lidia Santoro, Fabio Guolo, Paola Minetto, Marzia Defina, Patrizia Chiusolo, Matteo Fanin, Endri Mauro, Lara Aprile, Carla Mazzone, Fabio Trastulli, Maria Ciccone, Marco De Gobbi, Alessandro Cignetti, Eleonora De Bellis, Valentina Mancini, Alfonso Piciocchi, Marco Vignetti, Giovanni Marsili, Irene Della Starza, Renato Fanin, Mario Luppi, Felicetto Ferrara, Giovanni Pizzolo, Renato Bassan, Robin Foa, Anna Candoni

https://doi.org/10.3324/haematol.2024.285638

Review Articles

Articles

Safety and efficacy of acalabrutinib plus bendamustine and rituximab in patients with treatment-naive or relapsed / refractory mantle cell lymphoma: phase Ib trial (236 Online Views)

Tycel Phillips, Michael Wang, Tadeusz Robak, David Gallinson, Don Stevens, Krish Patel, Safaa Ramadan, Chuan-Chuan Wun, Wojciech Jurczak, Stephen D. Smith

https://doi.org/10.3324/haematol.2023.284896

Loncastuximab tesirine in Chinese patients with relapsed or refractory diffuse large B-cell lymphoma: a multicenter, open-label, single-arm, phase II trial (219 Online Views)

Ningjing Lin, Xiuhua Sun, Hui Zhou, Liqun Zou, Keshu Zhou, Lihong Liu, Haiyan Yang, Kai Hu, Qingqing Cai, Yao Liu, Jie Jin, Liling Zhang, Wenyu Li, Ye Guo, Wei Yang, Feng Luo, Zhenguang Wang, Rong Zhu, Lei Yang, Dan Song, Yuqin Song, Jun Zhu

https://doi.org/10.3324/haematol.2024.284973

BCAT1 is a NOTCH1 target and sustains the oncogenic function of NOTCH1 (194 Online Views)

Valeria Tosello, Ludovica Di Martino, Adonia E. Papathanassiu, Silvia Dalla Santa, Marco Pizzi, Lara Mussolin, Jingjing Liu, Pieter van Vlierberghe, Erich Piovan

https://doi.org/10.3324/haematol.2024.285552

Rituximab and lenalidomide for the treatment of relapsed or refractory indolent non-Hodgkin lymphoma: real-life experience (244 Online Views)

Giulio Cassanello, Esther Drill, Alfredo Rivas-Delgado, Michelle Okwali, Irem Isgor, Philip C. Caron, Zachary Epstein-Peterson, Paola Ghione, Paul Hamlin, Jennifer Lue, Steven M. Horwitz, Andrew M. Intlekofer, William Johnson, Anita Kumar, Alison Moskowitz, Ariela Noy, Colette Owens, Lia M. Palomba, Pallawi Torka, Pallavi Galera, Andrew D. Zelenetz, Gilles Salles, Lorenzo Falchi

https://doi.org/10.3324/haematol.2024.285600

Letters to the Editor

Outcomes of patients with primary central nervous system lymphoma following CD19-targeted chimeric antigen receptor T-cell therapy (583 Online Views)

Santiago Mercadal, Kwang Woo Ahn, Mariam Allbee-Johnson, Siddhartha Ganguly, Praveen Ramakrishnan Geethakumari, Sanghee Hong, Adriana Malone, Hemant Murthy, Attaphol Pawarode, Alejandro R. Sica, Melhem Solh, Celalettin Ustun, Mazyar Shadman, Craig S. Sauter, Mehdi Hamadani, Alex F. Herrera, Catherine J. Lee

https://doi.org/10.3324/haematol.2024.285613

Prognostic stratification in venetoclax-based acute myeloid leukemia treatments: the molecular prognostic risk signature tested in a real-world setting (170 Online Views)

Gaia Ciolli, Matteo Piccini, Francesco Mannelli, Giacomo Gianfaldoni, Barbara Scappini, Laura Fasano, Francesca Crupi, Elisa Quinti, Andrea Pasquini, Jessica Caroprese, Giada Rotunno, Fabiana Pancani, Leonardo Signori, Chiara Maccari, Fiorenza I. Vanderwert, Paola Guglielmelli, Alessandro M. Vannucchi

https://doi.org/10.3324/haematol.2024.285934

Adverse prognostic impact of KIT exon 17 mutations despite negative flow cytometric measurable residual disease in pediatric acute myeloid leukemia with RUNX1::RUNX1T1 (269 Online Views)

Shota Kato, Shin-Ichi Tsujimoto, Jun Matsubayashi, Shotaro Iwamoto, Hidefumi Hiramatsu, Yusuke Okuno, Tatsuya Kamitori, Kentaro Ohki, Takao Deguchi, Nobutaka Kiyokawa, Motohiro Kato, Junko Takita, Shiro Tanaka, Souichi Adachi, Daisuke Tomizawa, Norio Shiba

https://doi.org/10.3324/haematol.2024.286243

Aug 29, 2024

Editorial
Article

Combinatorial strategies targeting NEAT1 and AURKA as new potential therapeutic options for multiple myeloma (567 Online Views)

Noemi Puccio, Gloria Manzotti, Elisabetta Mereu, Federica Torricelli, Domenica Ronchetti, Michela Cumerlato, Ilaria Craparotta, Laura Di Rito, Marco Bolis, Valentina Traini, Veronica Manicardi, Valentina Fragliasso, Yvan Torrente, Nicola Amodio, Niccolò Bolli, Elisa Taiana, Alessia Ciarrocchi, Roberto Piva, Antonino Neri

https://doi.org/10.3324/haematol.2024.285470

Editorial
Article

Distinctive genomic features of human T-lymphotropic virus type 1-related adult T-cell leukemia-lymphoma in Western populations (466 Online Views)

Caroline S. Myers, Eli Williams, Carlos Barrionuevo Cornejo, Georgios Pongas, Ngoc L. Toomey, Jose A. Sanches, Maxime Battistella, Samuel Mo, Melissa Pulitzer, Cristopher A. Moskaluk, Govind Bhagat, Kenneth Ofori, Jonathan J. Davick, Octavio Servitje, Denis Miyashiro, Fina Climent, Kimberley Ringbloom, Daniela Duenas, Calvin Law, Sandro Casavilca Zambrano, Luis Malpica, Brady E. Beltran, Denisse Castro, Luciana Barreto, Carlos Brites, Jennifer R. Chapman, Jaehyuk Choi, Alejandro A. Gru, Juan C. Ramos

https://doi.org/10.3324/haematol.2024.285233

Articles

Utilization of allogeneic hematopoietic stem cell transplantation among patients with newly diagnosed acute myeloid leukemia in California: a population-based linked dataset study (152 Online Views)

Christa L. Meyer, Theresa H.M. Keegan, Ann Brunson, Jeffery J. Auletta, Lindsay M. Morton, Ted Wun, Sara J. Schonfeld, Bryan Valcarcel, Renata Abrahão, Rafeek A. Yusuf, Lori Muffly

https://doi.org/10.3324/haematol.2024.285648

T-cell receptor architecture and clonal tiding provide insight into the transformation trajectory of peripheral T-cell lymphomas (340 Online Views)

Edith Willscher, Christoph Schultheiß, Lisa Paschold, Franziska Lea Schümann, Paul Schmidt-Barbo, Benjamin Thiele, Marcus Bauer, Claudia Wickenhauser, Thomas Weber, Mascha Binder

https://doi.org/10.3324/haematol.2024.285395

Letters to the Editor

Characteristics and outcomes associated with CD2 and CD25 expression on bone marrow mast cells in patients with systemic mastocytosis (178 Online Views)

Julien Rossignol, Sophie Georgin-Lavialle, Danielle Canioni, Omer Beganovic, Chantal Brouzes, Olivier Fain, Maël Heiblig, Clément Gourguechon, Philippe Guilpain, Cristina Bulai-Livideanu, Stéphane Barete, Julie Agopian, Fabienne Brenet, Patrice Dubreuil, Richard Lemal, Olivier Tournilhac, Louis Terriou, David Launay, Laurence Bouillet, Catharina Chatain, Ghandi Damaj, Thomas Ballul, Celine Greco, Laura Polivka, Laurent Frenzel, Cécile Meni, Hassiba Bouktit, Dina Benabou, Clotilde Devin, Caroline Gaudy-Marqueste, Marie Gousseff, Edwige Le Mouel, Antoine Neel, Dana Ranta, Roland Jaussaud, Thierry Jo Molina, Julie Bruneau, Rose-Marie Javier, Fabien Pelletier, Florence Castelain, Frederique Retornaz, Quentin Cabrera, Patricia Zunic, Marie Pierre Gourin, Ewa Wierzbicka-Hainaut, Jean François Viallard, Christian Lavigne, Cyrille Hoarau, Isabelle Durieu, Sophie Dimicoli-Salazar, Jose Miguel Torregrosa-Diaz, Audrey Duval, Nicolas Garcelon, Jeremie Lespinasse, Angèle Soria, Yannick Chantran, Michel Arock, Christine Bodemer, Olivier Lortholary, Vahid Asnafi, Olivier Hermine, Ludovic Lhermitte

https://doi.org/10.3324/haematol.2024.285740

Aug 22, 2024

Editorial
Article

Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia (662 Online Views)

Mohd Minhajuddin, Amanda Winters, Haobin Ye, Shanshan Pei, Brett Stevens, Austin Gillen, Krysta Engel, Stephanie Gipson, Monica Ransom, Maria Amaya, Anagha Inguva, Maura Gasparetto, Mark J. Althoff, Regan Miller, Ian Shelton, Hunter Tolison, Anna Krug, Rachel Culp-Hill, Angelo D’Alessandro, Daniel W Sherbenou, Daniel A. Pollyea, Clayton Smith, Craig T Jordan

https://doi.org/10.3324/haematol.2023.284716

Letters to the Editor

Hodgkin/Reed-Sternberg cells induce GPNMB expression and release from macrophages to suppress T-cell responses to the Epstein-Barr virus-encoded LMP2A protein (178 Online Views)

Navta Masand, Tracey A. Perry, Matthew Pugh, Eanna Fennell, Aoife Hennessy, Wenbin Wei, Katerina Bouchalova, David Burns, Pamela Kearns, Graham Taylor, Katerina Vrzalikova, Paul G. Murray

https://doi.org/10.3324/haematol.2024.285319

Infection by Helicobacter pylori cytotoxin-A-associated antigen-positive strains is associated with iron deficiency anemia in a longitudinal birth cohort in Brazil (151 Online Views)

Dulciene M. M. Queiroz, Lucia L. C. Braga, Gifone A. Rocha, Sérgio A. Batista, Andreia M. C. Rocha, Mayuko Saito, William Checkley, Robert H. Gilman, Jean E. Crabtree

https://doi.org/10.3324/haematol.2024.285446

Comparing the clinical trial efficacy versus real-world effectiveness of treatments for multiple myeloma: a population-based study (345 Online Views)

Alissa Visram, Kelvin Kar-Wing Chan, Hsien Seow, Gregory Pond, Anastasia Gayowsky, Ghulam Rehman Mohyuddin, Arleigh McCurdy, Irwindeep Sandhu, Christopher Venner, Guido Lancman, Amaris Balitsky, Tom Kouroukis, Robert Bruins, Shaji Kumar, Rafael Fonseca, Hira Mian

https://doi.org/10.3324/haematol.2024.285768

Aug 15, 2024

Articles

Outcome of 421 adult patients with Philadelphia-negative acute lymphoblastic leukemia treated under an intensive program inspired by the GIMEMA LAL1913 clinical trial: a Campus ALL study (335 Online Views)

Davide Lazzarotto, Marco Cerrano, Cristina Papayannidis, Sabina Chiaretti, Federico Mosna, Nicola Fracchiolla, Patrizia Zappasodi, Silvia Imbergamo, Maria Ilaria Del Principe, Monia Lunghi, Federico Lussana, Matteo Piccini, Monica Fumagalli, Michelina Dargenio, Prassede Salutari, Fabio Forghieri, Teresa Giulia Da Molin, Massimiliano Bonifacio, Matteo Olivi, Fabio Giglio, Silvia Trappolini, Matteo Leoncin, Antonino Mule, Mario Delia, Crescenza Pasciolla, Francesco Grimaldi, Benedetta Cambo, Lidia Santoro, Fabio Guolo, Paola Minetto, Marzia Defina, Patrizia Chiusolo, Matteo Fanin, Endri Mauro, Lara Aprile, Carla Mazzone, Fabio Trastulli, Maria Ciccone, Marco De Gobbi, Alessandro Cignetti, Eleonora De Bellis, Valentina Mancini, Alfonso Piciocchi, Marco Vignetti, Giovanni Marsili, Irene Della Starza, Renato Fanin, Mario Luppi, Felicetto Ferrara, Giovanni Pizzolo, Renato Bassan, Robin Foa, Anna Candoni

https://doi.org/10.3324/haematol.2024.285638

Letters to the Editor

A multi-center, phase Ib study of subcutaneous administration of isatuximab in combination with pomalidomide and dexamethasone in patients with relapsed/refractory multiple myeloma (681 Online Views)

Hang Quach, Gurdeep Parmar, Enrique M. Ocio, H. Miles Prince, Albert Oriol, Helen Crowther, Nobuhiro Tsukada, Pierre Bories, Sumit Madan, Nitya Nathwani, Kazutaka Sunami, Dorothee Semiond, Disa Yu, Paul Cordero, Sandrine Macé, Florence Suzan, Philippe Moreau

https://doi.org/10.3324/haematol.2023.284730

Cd39 and P2rx7-Wnt signaling enhance blast pathogenicity in an experimental model of acute myeloid leukemia (230 Online Views)

Lili Feng, Haohai Zhang, Changchuin Mao, Paola de Andrade Mello, Dina Stroopinsky, Eva Csizmadia, Jialin Zhou, David Avigan, Jinming Yu, Wenda Gao, Simon C. Robson

https://doi.org/10.3324/haematol.2024.285547

A novel prognostic nomogram based on imaging and molecular parameters for newly diagnosed extranodal natural killer/T-cell lymphoma patients (240 Online Views)

Dezhi Huang, Fu Li, Shijia Lin, Jing Xia, Bangdong Liu, Xinlei Li, Naya Ma, Yishuo Duan, Yunjing Zeng, Sha Zhou, Shuhan Tang, Wenqiu Huang, Lingyi Rao, Li Gao, Qiong Li, Xi Zhang, Jun Rao

https://doi.org/10.3324/haematol.2024.285362

Comments

Aug 8, 2024

Editorials
Article

Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma (804 Online Views)

Nicholas Davies, Tegan Francis, Ceri Oldreive, Maria Azam, Jordan Wilson, Philip J. Byrd, Megan Burley, Archana Sharma-Oates, Peter Keane, Sael Alatawi, Martin R. Higgs, Zbigniew Rudzki, Maha Ibrahim, Tracey Perry, Angelo Agathanggelou, Anne-Marie Hewitt, Edward Smith, Constanze Bonifer, Mark O’Connor, Josep V. Forment, Paul G. Murray, Eanna Fennell, Gemma Kelly, Catherine Chang, Grant S. Stewart, Tatjana Stankovic, Marwan Kwok, Alexander Malcolm Taylor

https://doi.org/10.3324/haematol.2023.284404

Articles

LP-118 is a novel B-cell lymphoma 2 / extra-large inhibitor that demonstrates efficacy in models of venetoclax-resistant chronic lymphocytic leukemia (449 Online Views)

Janani Ravikrishnan, Daisy Y. Diaz-Rohena, Elizabeth Muhowski, Xiaokui Mo, Tzung-Huei Lai, Shrilekha Misra, Charmelle D. Williams, John Sanchez, Andrew Mitchell, Suresh Satpati, Elizabeth Perry, Tierney Kaufman, Chaomei Liu, Arletta Lozanski, Gerard Lozanski, KerryA Rogers, Adam S. Kittai, Seema A. Bhat, Mary C. Collins, Matthew S. Davids, Nitin Jain, William G. Wierda, Rosa Lapalombella, John C. Byrd, Fenlai Tan, Yi Chen, Yu Chen, Yue Shen, Stephen P. Anthony, Jennifer A. Woyach, Deepa Sampath

https://doi.org/10.3324/haematol.2023.284353

Distinctive genomic features of human T-lymphotropic virus type 1-related adult T-cell leukemia-lymphoma in Western populations (466 Online Views)

Caroline S. Myers, Eli Williams, Carlos Barrionuevo Cornejo, Georgios Pongas, Ngoc L. Toomey, Jose A. Sanches, Maxime Battistella, Samuel Mo, Melissa Pulitzer, Cristopher A. Moskaluk, Govind Bhagat, Kenneth Ofori, Jonathan J. Davick, Octavio Servitje, Denis Miyashiro, Fina Climent, Kimberley Ringbloom, Daniela Duenas, Calvin Law, Sandro Casavilca Zambrano, Luis Malpica, Brady E. Beltran, Denisse Castro, Luciana Barreto, Carlos Brites, Jennifer R. Chapman, Jaehyuk Choi, Alejandro A. Gru, Juan C. Ramos

https://doi.org/10.3324/haematol.2024.285233

Immunoglobulin prophylaxis prevents hospital admissions for fever in pediatric acute lymphoblastic leukemia: results of a multicenter randomized trial (489 Online Views)

Kirsten A. Thus, Hester A. de Groot-Kruseman, Pauline Winkler-Seinstra, Marta Fiocco, Heidi Segers, Cor van den Bos, Inge M. van der Sluis, Wim J.E. Tissing, Margreet A. Veening, Christian Michel Zwaan, Cornelis M. van Tilburg, Rob Pieters, Marc Bierings

https://doi.org/10.3324/haematol.2024.285428

Hematopoietic cell transplantation for older acute myeloid leukemia patients in first complete remission: results of a randomized phase III study (844 Online Views)

Dietger Niederwieser, Dirk Hasenclever, Wolfgang E. Berdel, Bart J. Biemond, Haifa Al-Ali, Yves Chalandon, Michel van Gelder, Christian Junghanß, Gösta Gahrton, Mathias Hänel, Rüdiger Hehlmann, Thomas Heinicke, Andreas Hochhaus, Simona Iacobelli, Rien van Marwijk Kooy, Nicolaus Kröger, Jeroen Janssen, Madlen Jentzsch, Frank Breywisch, Mohamad Mohty, Stavroula Masouridi-Levrat, Gert Ossenkoppele, Jacob Passweg, Wolfram Pönisch, Johannes Schetelig, Christoph Schliemann, Sebastian Schwind, Matthias Stelljes, Leo F. Verdonck, Vladan Vucinic, Bob Löwenberg, Jan Cornelissen

https://doi.org/10.3324/haematol.2024.285879

Letters to the Editor

A phase II study of post-remission therapy with pembrolizumab in older patients with acute myeloid leukemia (231 Online Views)

Kevin Quann, Konstantinos Lontos, Alison Sehgal, Anastasios Raptis, Annie Im, Robert L. Redner, Kathleen A. Dorritie, Mounzer Agha, Jing-Zhou Hou, Rafic Farah, James Rossetti, Daniel P. Normolle, Theresa L. Whiteside, Yen-Michael Sheng Hsu, Michael Boyiadzis

https://doi.org/10.3324/haematol.2024.285313

Contribution of copy number to improve risk stratification of adult T-cell acute lymphoblastic leukemia patients enrolled in measurable residual disease-oriented trials (197 Online Views)

Celia Gonzalez-Gil, Mireia Morgades, Thaysa Lopes, Francisco Fuster-Tormo, Pau Montesinos, Pere Barba, Marina Diaz-Beya, Lourdes Hermosin, Clara Maluquer, Jose Gonzalez-Campos, Teresa Bernal, Marta Sitges Arriaga, Lurdes Zamora, Marta Pratcorona, Rodrigo Martino, Maria Jose Larrayoz, Teresa Artola, Anna Torrent, Ferran Vall-llovera, Mar Tormo, Cristina Gil, Andres Novo, Pilar Martinez-Sanchez, Jordi Ribera, Maria-Paz Queipo, Teresa Gonzalez-Martinez, Monica Cabrero, Antonia Cladera, Jose Cervera, Alberto Orfao, Josep Maria Ribera, Eulalia Genesca

https://doi.org/10.3324/haematol.2024.285416

Repurposing CD19-directed immunotherapies for pediatric t(8;21) acute myeloid leukemia (499 Online Views)

Farnaz Barneh, Joost B. Koedijk, Noa E. Wijnen, Tom Meulendijks, Minoo Ashtiani, Ester Dunnebach, Noël Dautzenberg, Annelisa M. Cornel, Anja Krippner-Heidenreich, Kim Klein, Michel C. Zwaan, Jürgen Kuball, Stefan Nierkens, Jacqueline Cloos, Gertjan J.L. Kaspers, Olaf Heidenreich

https://doi.org/10.3324/haematol.2024.285707

Case Reports

Aug 1, 2024

Letters to the Editor

Superior survival with allogeneic hematopoietic stem cell transplantation versus chemotherapy for high-risk adult acute lymphoblastic leukemia in a PDT-ALL-2016 pediatric-inspired cohort (271 Online Views)

Junjie Chen, Zihong Cai, Zicong Huang, Jieping Lin, Zhixiang Wang, Jiawang Ou, Xiuli Xu, Bingqing Tang, Chenhao Ding, Jia Li, Ren Lin, Ting Zhang, Li Xuan, Qifa Liu, Hongsheng Zhou

https://doi.org/10.3324/haematol.2024.285590

Comments

Case Reports

Ponatinib alone or with chemo-immunotherapy in heavily pre-treated Philadelphia-like acute lymphoblastic leukemia: a CAMPUS ALL real-life study (384 Online Views)

Francesca Kaiser, Monia Lunghi, Deborah Cardinali, Vittorio Bellomarino, Marco Beldinanzi, Irene Della Starza, Francesco Malfona, Claudia M. Basilico, Marzia Defina, Sara Mastaglio, Fabio Giglio, Davide Lazzarotto, Prassede Salutari, Matteo Piccini, Valeria Cardinali, Antonio Pierini, Nicola S. Fracchiolla, Federica Di Biase, Mario Annunziata, Mariangela Di Trani, Robin Foa, Sabina Chiaretti

https://doi.org/10.3324/haematol.2024.285258

Expanding the genetic landscape of congenital neutropenia: CXCR2 mutations in three families revealed through whole exome sequencing (298 Online Views)

Maksim Klimiankou, Ivan Tesakov, Grigorios Tsaknakis, Erasmia Boutakoglou, Irene Mavroudi, Malte Ritter, Marc Sturm, Julia Skokowa, Helen A. Papadaki

https://doi.org/10.3324/haematol.2024.285569

Spotlight Review

Jul 25, 2024

Editorials

Articles

Co-shared genomic alterations within tumors from patients with both myeloproliferative neoplasms and lymphoma (262 Online Views)

Johanne M. Holst, Martin B. Pedersen, Marie B. Enemark, Marcus C. Hansen, Patrick R. Noerhave, Trine L. Plesner, Henrik Frederiksen, Michael B. Moeller, Stephen J. Hamilton-Dutoit, Peter Noergaard, Bo K. Mortensen, Hans B. Ommen, Jesper Stentoft, Wayne Tam, Maja Ludvigsen, Wing C. Chan, Nicolai J. Birkbak, Giorgio Inghirami, Francesco d’Amore

https://doi.org/10.3324/haematol.2023.283798

A transgenic mouse model of Down syndrome acute lymphoblastic leukemia identifies targetable vulnerabilities (244 Online Views)

Jacob J. Junco, Max Rochette, Michelle Alozie, Raushan Rashid, Maci Terrell, Barry Zorman, Pavel Sumazin, Lauren Rowland, Gino Dettorre, Reid T. Powell, Clifford C. Stephan, Peter J. Davies, Margarita Martinez-Moczygemba, Jun J. Yang, Karen R. Rabin

https://doi.org/10.3324/haematol.2023.284761

Unlocking the therapeutic potential of selective CDK7 and BRD4 Inhibition against multiple myeloma cell growth (329 Online Views)

Yao Yao, Shuhui Deng, Jessica Fong Ng, Mei Yuan, Chandraditya Chakraborty, Vera JoyWeiler, Nikhil Munshi, Mariateresa Fulciniti

https://doi.org/10.3324/haematol.2024.285491

Letters to the Editor

Increased frequency of clonal hematopoiesis of indeterminate potential in Bloom syndrome probands and carriers (225 Online Views)

Isabella Lin, Angela Wei, Tsumugi A. Gebo, Paul C. Boutros, Maeve Flanagan, Nicole Kucine, Christopher Cunniff, Valerie A. Arboleda, Vivian Y. Chang

https://doi.org/10.3324/haematol.2024.285239

Jul 18, 2024

Editorials
Article

Azacitidine as epigenetic priming for chemotherapy is safe and well-tolerated in infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia: Children’s Oncology Group trial AALL15P1 (490 Online Views)

Erin M. Guest, John A. Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew J. Carroll, Nyla A. Heerema, Holly R. Kubaney, Margaret A. August, Sidharth Ramesh, Byunggil Yoo, Midhat S. Farooqi, Melinda G. Pauly, Daniel S. Wechsler, Rodney R. Miles, Joel M. Reid, Cynthia D. Kihei, Lia Gore, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown

https://doi.org/10.3324/haematol.2024.285158

Articles

Atezolizumab combined with immunogenic salvage chemoimmunotherapy in patients with transformed diffuse large B-cell lymphoma (425 Online Views)

Tamer Othman, Paul Frankel, Pamela Allen, Leslie L. Popplewell, Geoffrey Shouse, Tanya Siddiqi, Alexey V. Danilov, Nora Ruel, Shari Daniels, Lacolle Peters, Stella Khoo, Steven T. Rosen, Elad Sharon, Miguel Villalona-Calero, Christopher Ruel, Joseph Tuscano, Alex F. Herrera

https://doi.org/10.3324/haematol.2024.285185

Multiple myeloma in the young: insights on prognosis, clinical features and treatment outcome derived from nationwide German registry data and a nested multicenter sample (441 Online Views)

Abdulaziz Kamili, Paymon Ahmadi, Lisa Leypoldt, Franziska Marquard, Christoph Schaefers, Ricardo Kosch, Frederik Peters, Henrik Kusche, Tanja Zamrik, Christine Hanoun, Maximilian Seib, Evgenii Shumilov, Theo Leitner, Cyrus Khandanpour, Carsten Bokemeyer, Katja Weisel, Susanne Ghandili

https://doi.org/10.3324/haematol.2024.285630

Risk of infections in multiple myeloma. A population-based study on 8672 multiple myeloma patients diagnosed 2008-2021 from the Swedish Myeloma Registry (389 Online Views)

Cecilie Hveding Blimark, Kristina Carlson, Christopher Day, Sigrun Einarsdottir, Gunnar Juliusson, Moshtak Karma, Dorota Knut-Bojanowska, Gunnar Larfors, Ingemar Turesson, Mariana Villegas-Scivetti, Ingigerdur Sverrisdóttir

https://doi.org/10.3324/haematol.2024.285645

Letters to the Editor

Reference interval of free light chains ratio in patients with end-stage renal disease on chronic hemodialysis (232 Online Views)

Camila Peña, Ricardo Valjalo, Ramón Pérez, Marco Álvarez, Pablo Bustamante, Esteban Forray, Viviana Balboa, Alexis Bondi

https://doi.org/10.3324/haematol.2024.285093

Co-transfection of murine NXPE2 and murine glycophorin A confers reactivity with Ter-119 (220 Online Views)

Gregory R. Keele, Ariel M. Hay, Nadia K. Holness, Arijita Jash, Sarah E. Ewald, Callan O’Connor, Matthew Vincent, Monika Dzieciatkowska, Angelo D’Alessandro, Gary A. Churchill, James C. Zimring

https://doi.org/10.3324/haematol.2024.285168

Polytypic B cells, monotypic/monoclonal B-cell proliferations, and neoplastic T cells diverge from TET2-/DNMT3A-mutant clonal hematopoiesis in follicular helper T-cell lymphomas (408 Online Views)

Natasha E. Lewis, Kseniya Petrova-Drus, Rohan Sardana, Sarah Huet, Qi Gao, Shenon Sethi, Chad Vanderbilt, Wenbin Xiao, Mikhail Roshal, Jeeyeon Baik, Himanshu Bhurtel, Alison J. Moskowitz, Steven M. Horwitz, Ahmet Dogan

https://doi.org/10.3324/haematol.2024.285183

No clear benefit of preventive cranial radiotherapy in childhood Philadelphia-positive acute lymphoblastic leukemia: a retrospective analysis of the EsPhALL2010 study (283 Online Views)

Valentino Conter, Maria Grazia Valsecchi, Paola De Lorenzo, Virginie Gandemer, Mats Heyman, Vaskar Saha, Paulina Diaz, Chi-Kong Li, Andishe Attarbaschi, Gabriele Escherich, Jan Stary, Martin Schrappe, Rob Pieters, Gunnar Cario, Andrea Biondi

https://doi.org/10.3324/haematol.2024.285253

A targeted gene signature stratifying mediastinal gray zone lymphoma into classical HL-like or PMBL-like subtypes (643 Online Views)

Grazia Gargano, Maria Carmela Vegliante, Flavia Esposito, Susanna A. Pappagallo, Elena Sabattini, Claudio Agostinelli, Stefano A. Pileri, Valentina Tabanelli, Maurilio Ponzoni, Luisa Lorenzi, Fabio Facchetti, Arianna Di Napoli, Marco Lucioni, Marco Paulli, Lorenzo Leoncini, Stefano Lazzi, Stefano Ascani, Giuseppina Opinto, Gian Maria Zaccaria, Giacomo Volpe, Paolo Mondelli, Antonella Bucci, Laura Selicato, Antonio Negri, Giacomo Loseto, Felice Clemente, Anna Scattone, Alfredo F. Zito, Luca Nassi, Nicoletta Del Buono, Attilio Guarini, Sabino Ciavarella

https://doi.org/10.3324/haematol.2024.285266

Spotlight Review

Jul 11, 2024

Editorials
Article

IKZF1 gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia (524 Online Views)

Britt M. T. Vervoort, Miriam Butler, Kari J.T. Grünewald, Dorette S. van Ingen Schenau, Trisha M. Tee, Luc Lucas, Alwin D. R. Huitema, Judith M. Boer, Beat C. Bornhauser, Jean-Pierre Bourquin, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

https://doi.org/10.3324/haematol.2023.284357

Editorials
Article

Decision analysis for transplant candidates with primary myelofibrosis in the ruxolitinib era (529 Online Views)

Yosuke Okada, Hideki Nakasone, Shunto Kawamura, Kosuke Takano, Kazuki Yoshimura, Masaharu Tamaki, Akari Matsuoka, Takuto Ishikawa, Tomohiro Meno, Yuhei Nakamura, Masakatsu Kawamura, Junko Takeshita, Nozomu Yoshino, Yukiko Misaki, Machiko Kusuda, Aki Tanihara, Shun-ichi Kimura, Shinichi Kako, Yoshinobu Kanda

https://doi.org/10.3324/haematol.2024.285256

Articles

Umbilical cord blood T cells can be isolated and enriched by CD62L selection for use in 'off the shelf' chimeric antigen receptor T-cell therapies to widen transplant options (608 Online Views)

Christos Georgiadis, Lauren Nickolay, Farhatullah Syed, Hong Zhan, Soragia Athina Gkazi, Annie Etuk, Ulrike Abramowski-Mock, Roland Preece, Piotr Cuber, Stuart Adams, Giorgio Ottaviano, Waseem Qasim

https://doi.org/10.3324/haematol.2024.285101

Combinatorial strategies targeting NEAT1 and AURKA as new potential therapeutic options for multiple myeloma (567 Online Views)

Noemi Puccio, Gloria Manzotti, Elisabetta Mereu, Federica Torricelli, Domenica Ronchetti, Michela Cumerlato, Ilaria Craparotta, Laura Di Rito, Marco Bolis, Valentina Traini, Veronica Manicardi, Valentina Fragliasso, Yvan Torrente, Nicola Amodio, Niccolò Bolli, Elisa Taiana, Alessia Ciarrocchi, Roberto Piva, Antonino Neri

https://doi.org/10.3324/haematol.2024.285470

Single-point and kinetics of peripheral residual disease by mass spectrometry to predict outcome in patients with high risk smoldering multiple myeloma included in the GEM-CESAR trial (653 Online Views)

Noemí Puig, Cristina Agulló, Teresa Contreras, José-Juan Pérez, Irene Aires, María-José Calasanz, Ramón García-Sanz, Sergio Castro, Joaquín Martínez-López, Paula Rodríguez-Otero, Verónica González-Calle, Marta S González, Albert Oriol, Norma C Gutiérrez, Rafael Ríos-Tamayo, Laura Rosiñol, Miguel-Ángel Álvarez, Joan Bargay, Ana-Pilar González-Rodríguez, Adrián Alegre, Fernando Escalante, María-Belén Iñigo, Javier de la Rubia, Ana-Isabel Teruel, Felipe de Arriba, Luis Palomera, Miguel T Hernández, Javier López-Jiménez, Marta Reinoso, Aránzazu García-Mateo, Enrique M Ocio, Joan Bladé, Juan-José Lahuerta, María-Teresa Cedena, Bruno Paiva, Jesús F San Miguel, María-Victoria Mateos

https://doi.org/10.3324/haematol.2024.285742

Letters to the Editor

Rituximab maintenance after bendamustine-based treatment for follicular lymphoma and mantle cell lymphoma may exert a negative influence on SARS-CoV-2 infection outcomes (435 Online Views)

Ángel Serna, Víctor Navarro, Gloria Iacoboni, Laia López, Juan-Manuel Sancho, Eva González-Barca, Alberto López-García, Raúl Córdoba, Adolfo Sáez, Ana Jiménez Ubieto, Ainara Ferrero, Tomás García, Ángela Sánchez, Cristina García, Marc Bosch, Alba Cabirta, Moraima Jiménez, Ana Marín-Niebla, Francesc Bosch, Pau Abrisqueta

https://doi.org/10.3324/haematol.2024.285219

Excellent outcome of children/adolescents with primary mediastinal large B-cell lymphoma treated with FAB/LMB-based chemotherapy regimen with rituximab (327 Online Views)

Marie Emilie Dourthe, Anne Auperin, Charlotte Rigaud, Melissa Barbati, Jacinthe Bonneau, Nimrod Buchbinder, Marie-Laure Couec, Peggy Dartigues, Stéphane Ducassou, Nathalie Garnier, Stéphanie Haouy, Bénédicte Jonca, Anne Jourdain, Amaury Leruste, Thierry Molina, Françoise Montravers, Marlène Pasquet, Aurélie Phulpin, Maryline Poirée, Mathieu Simonin, Alexandra Spiegel, Arnauld Verschuur, Thierry Leblanc, Judith Landman-Parker, Catherine Patte, Véronique Minard-Colin

https://doi.org/10.3324/haematol.2024.285403

Microbiota signature of oral chronic graft-versus-host disease 6+ years after transplantation (299 Online Views)

Armin Rashidi, Lang Liang, Ted Gooley, Philippe P. Hujoel, Alex Zevin, Marilynn Rothen, Mary K. Hagstrom, Corey Cutler, Stephanie J. Lee, David R. Dean, Hervé Y. Sroussi, Nathaniel S. Treister

https://doi.org/10.3324/haematol.2024.285650

Extending duration of letermovir prophylaxis in haploidentical stem cell transplantation (328 Online Views)

Pongthep Vittayawacharin, Benjamin J. Lee, Shawn Griffin, Jean Doh, Julie Smith, Hannah Nam, Emily Blodget, Deepa Jeyakumar, Piyanuch Kongtim, Stefan O. Ciurea

https://doi.org/10.3324/haematol.2024.285766

Comments

Jul 4, 2024

Editorials
Article

Pilot study of lung cancer screening for survivors of Hodgkin lymphoma (545 Online Views)

Rachel Broadbent, Philip Crosbie, Christopher J. Armitage, Ben Taylor, Sean Tenant, Joseph Mercer, John Radford, Kim Linton

https://doi.org/10.3324/haematol.2023.283287

Editorials
Article

Outcomes and genetic dynamics of acute myeloid leukemia at first relapse (1269 Online Views)

Alex Bataller, Hagop Kantarjian, Alexandre Bazinet, Tapan Kadia, Naval Daver, Courtney D. DiNardo, Gautam Borthakur, Sanam Loghavi, Keyur Patel, Guilin Tang, Koji Sasaki, Nicholas J. Short, Musa Yilmaz, Ghayas C. Issa, Yesid Alvarado, Guillermo Montalban-Bravo, Abhishek Maiti, Hussein A. Abbas, Koichi Takahashi, Sherry Pierce, Elias Jabbour, Guillermo Garcia-Manero, Farhad Ravandi

https://doi.org/10.3324/haematol.2024.285057

Articles

A novel role of AURKA kinase in erythroblast enucleation (489 Online Views)

Yuanlin Xu, Peijun Jia, Yating Li, Huan Zhang, Jingxin Zhang, Wanxin Li, Yazhe Zhen, Yan Li, Jiaming Cao, Tingting Zheng, Yihan Wang, Yanyan Liu, Xiuli An, Shijie Zhang

https://doi.org/10.3324/haematol.2023.284873

LSD1/KDM1A and GFI1B repress endothelial fate and induce hematopoietic fate in induced pluripotent stem cell-derived hemogenic endotheliums (557 Online Views)

Huan Zhang, Marten Hansen, Franca di Summa, Marieke von Lindern, Nynke Gillemans, Wilfred F.J. van IJcken, Arthur Flohr Svendsen, Sjaak Philipsen, Bert van der Reijden, Eszter Varga, Emile van den Akker

https://doi.org/10.3324/haematol.2024.285214

Letters to the Editor

Response to DA-EPOCH-R is associated with activation of 'fitter' cytotoxic T-cells in patients with newly diagnosed double and triple hit high-grade B-cell lymphoma (359 Online Views)

A. Vera de Jonge, Wassilis S.C. Bruins, Carolien Duetz, Charlotte L.B.M. Korst, Rosa Rentenaar, Meliha Cosovic, Merve Eken, Marie-Jose Kersten, Yorick Sandberg, Rozemarijn S. van Rijn, Rob Fijnheer, Pim Mutsaers, Vibeke K.J. Vergote, Djamila Issa, Aart Beeker, Yavuz M. Bilgin, Otto Visser, Erik van Werkhoven, Margaretha G.M. Roemer, Martine E.D. Chamuleau, Tuna Mutis

https://doi.org/10.3324/haematol.2024.285170

Case Reports

Jun 27, 2024

Editorials
Article

CD74 is expressed in a subset of pediatric acute myeloid leukemia patients and is a promising target for therapy: a report from the Children’s Oncology Group (735 Online Views)

Andrew J. Menssen, Chad A. Hudson, Todd Alonzo, Robert Gerbing, Laura Pardo, Amanda Leonti, Jacqueline A. Cook, Fan-Chi Hsu, Loren L. Lott, Fangyan Dai, Collette Fearing, Keely Ghirardelli, Tiffany Hylkema, Katherine Tarlock, Keith R. Loeb, Edward A. Kolb, Todd Cooper, Jessica Pollard, Denise A. Wells, Michael R. Loken, Richard Aplenc, Soheil Meshinchi, Lisa Eidenschink Brodersen

https://doi.org/10.3324/haematol.2023.283757

Articles

Core regions in immunoglobulin heavy chain enhancers essential for survival of non-Hodgkin lymphoma cells are identified by a CRISPR interference screen (508 Online Views)

Marta Elżbieta Kasprzyk, Weronika Sura, Marta Podralska, Marta Kazimierska, Annika Seitz, Wojciech Łosiewski, Tomasz Woźniak, Jeroen E. J. Guikema, Arjan Diepstra, Joost Kluiver, Anke van den Berg, Natalia Rozwadowska, Agnieszka Dzikiewicz-Krawczyk

https://doi.org/10.3324/haematol.2023.284672

Lysosomal acid lipase A modulates leukemia stem cell response to venetoclax/tyrosine kinase inhibitor combination therapy in blast phase chronic myeloid leukemia (662 Online Views)

Mohd Minhajuddin, Amanda Winters, Haobin Ye, Shanshan Pei, Brett Stevens, Austin Gillen, Krysta Engel, Stephanie Gipson, Monica Ransom, Maria Amaya, Anagha Inguva, Maura Gasparetto, Mark J. Althoff, Regan Miller, Ian Shelton, Hunter Tolison, Anna Krug, Rachel Culp-Hill, Angelo D’Alessandro, Daniel W Sherbenou, Daniel A. Pollyea, Clayton Smith, Craig T Jordan

https://doi.org/10.3324/haematol.2023.284716

Blockade of the CD47/SIRPα checkpoint axis potentiates the macrophage-mediated anti-tumor efficacy of tafasitamab (734 Online Views)

Alexander Biedermann, Maria Patra-Kneuer, Dimitrios Mougiakakos, Maike Büttner-Herold, Doris Mangelberger-Eberl, Johannes Berges, Christian Kellner, Sarah Altmeyer, Jörg Thomas Bittenbring, Christian Augsberger, Kristina Ilieva-Babinsky, Stefan Haskamp, Fabian Beier, Christopher Lischer, Julio Vera, Anja Lührmann, Simone Bertz, Simon Völkl, Benedikt Jacobs, Stefan Steidl, Andreas Mackensen, Heiko Bruns

https://doi.org/10.3324/haematol.2023.284795

Safety and efficacy of flumatinib as later-line therapy in patients with chronic myeloid leukemia (506 Online Views)

Yunfan Yang, Yuntao Liu, Hui Sun, Li Meng, Hai Lin, Chunyan Chen, Jianda Hu, Xuliang Shen, Minghui Duan, Yanli Zhang, Dilinazi Abulaiti, Jinghua Wang, Hongqian Zhu, Luoming Hua, Qing Leng, Chun Zhang, Lili Sun, Weiming Li, Huanling Zhu, Bingcheng Liu, Jianxiang Wang

https://doi.org/10.3324/haematol.2023.284892

Letters to the Editor

Respiratory syncytial virus and other vaccine-preventable infections in Multiple Myeloma. A population-based study on 8672 myeloma patients diagnosed 2008-2021 from the Swedish Myeloma Registry (298 Online Views)

Sigrun Einarsdottir, Ingigerdur Sverrisdottir, Mariana Villegas-Scivetti, Chris Day, Ingemar Turesson, Gunnar Juliusson, Markus Hansson, Gunnar Larfors, Cecilie Hveding Blimark

https://doi.org/10.3324/haematol.2024.285161

Comments

Jun 20, 2024

Articles

A first-in-class Wiskott-Aldrich syndrome protein activator with anti-tumor activity in hematologic cancers (693 Online Views)

Filippo Spriano, Giulio Sartori, Jacopo Sgrignani, Laura Barnabei, Alberto J. Arribas, Matilde Guala, Ana Maria Carrasco Del Amor, Meagan R. Tomasso, Chiara Tarantelli, Luciano Cascione, Gaetanina Golino, Maria E Riveiro, Roberta Bortolozzi, Antonio Lupia, Francesco Paduano, Samuel Huguet, Keyvan Rezai, Andrea Rinaldi, Francesco Margheriti, Pedro Ventura, Greta Guarda, Giosuè Costa, Roberta Rocca, Alberto Furlan, Luuk M. Verdonk, Paolo Innocenti, Nathaniel I. Martin, Giampietro Viola, Christoph Driessen, Emanuele Zucca, Anastasios Stathis, Digvijay Gahtory, Maurits van den Nieuwboer, Beat Bornhauser, Stefano Alcaro, Francesco Trapasso, Susana Cristobal, Shae B. Padrick, Natalina Pazzi, Franco Cavalli, Andrea Cavalli, Eugenio Gaudio, Francesco Bertoni

https://doi.org/10.3324/haematol.2022.282672

Anti-CD19 chimeric antigen receptor T-cell therapy has less efficacy in Richter transformation than in de novo large B-cell lymphoma and transformed low-grade B-cell lymphoma (828 Online Views)

Ohad Benjamini, Shalev Fried, Roni Shouval, Jessica R. Flynn, Ofrat Beyar-Katz, Lori A Leslie, Tsilla Zucherman, Ronit Yerushalmi, Noga Shem-Tov, Maria Lia Palomba, Ivetta Danylesko, Inbal Sdayoor, Hila Malka, Orit Itzhaki, Hyung Suh, Sean M. Devlin, Ronit Marcus, Parastoo B Dahi, Elad Jacoby, Gunjan L Shah, Craig S Sauter, Andrew Ip, Miguel-Angel Perales, Arnon Nagler, Avichai Shimoni, Michael Scordo, Abraham Avigdor

https://doi.org/10.3324/haematol.2023.284664

Brexucabtagene autoleucel in relapsed or refractory mantle cell lymphoma, intention-to-treat use in the DESCAR-T registry (543 Online Views)

Charles Herbaux, Caroline Bret, Emmanuel Bachy, Pierre Bories, Roberta Di Blasi, Alexis Cuffel, Thomas Gastinne, Thierry Lamy, Mikael Roussel, Krimo Bouabdallah, David Beauvais, Guillaume Cartron, Jacques-Olivier Bay, Didier Blaise, Marie-Therese Rubio, Mohamad Mohty, Fabien Le Bras, Olivier Casasnovas, Julien Guy, Stephanie Guidez, Cristina Castilla Llorente, Olivier Hermine, Laurianne Drieu La Rochelle, Sylvain Carras, Blandine Guffroy, Sophie Caillat-Zucman, Roch Houot, Steven Le Gouill

https://doi.org/10.3324/haematol.2023.284786

Decision analysis for transplant candidates with primary myelofibrosis in the ruxolitinib era (529 Online Views)

Yosuke Okada, Hideki Nakasone, Shunto Kawamura, Kosuke Takano, Kazuki Yoshimura, Masaharu Tamaki, Akari Matsuoka, Takuto Ishikawa, Tomohiro Meno, Yuhei Nakamura, Masakatsu Kawamura, Junko Takeshita, Nozomu Yoshino, Yukiko Misaki, Machiko Kusuda, Aki Tanihara, Shun-ichi Kimura, Shinichi Kako, Yoshinobu Kanda

https://doi.org/10.3324/haematol.2024.285256

Letters to the Editor

FLT3 inhibitors potentially improve response rates in acute myeloid leukemia harboring t(6;9)(DEK::NUP214): The Mayo Clinic experience (180 Online Views)

Clifford M. Csizmar, Antoine N. Saliba, Patricia T. Greipp, Hassan Alkhateeb, Kebede H. Begna, James M. Foran, Naseema Gangat, William J. Hogan, C. Christopher Hook, Mark R. Litzow, Abhishek A. Mangaonkar, Jeanne M. Palmer, Animesh Pardanani, Mithun V. Shah, Ayalew Tefferi, Mehrdad Hefazi Torghabeh, Alexandra P. Wolanskyj-Spinner, Mrinal M. Patnaik, Scott H Kaufmann, Aref Al-Kali

https://doi.org/10.3324/haematol.2024.285359

ASXL1/TET2 genotype-based risk stratification outperforms ASXL1 mutational impact and is independent of mutant variant allele fractions in chronic myelomonocytic leukemia (347 Online Views)

Clifford M. Csizmar, Mark Gurney, Rashmi Kanagal-Shamanna, Kelly Chien, Danielle Hammond, Terra L. Lasho, Christy M. Finke, Christopher Dean, Anuya Natu, Abhishek A. Mangaonkar, Aref Al-Kali, Naseema Gangat, Ayalew Tefferi, Hassan Alkhateeb, Guillermo Garcia-Manero, Rami S. Komrokji, Najla A. Ali, Eric Padron, Guillermo Montalban-Bravo, Mrinal M. Patnaik

https://doi.org/10.3324/haematol.2024.285410

Jun 13, 2024

Review Articles

Articles

Event-free survival at 36 months is a suitable endpoint for diffuse large B-cell lymphoma patients treated with immunochemotherapy: real-world evidence from the North Japan Hematology Study Group (639 Online Views)

Koh Izumiyama, Tasuku Inao, Hideki Goto, Shinpei Harada, Hajime Senjo, Keito Suto, Junichi Hashiguchi, Reiki Ogasawara, Tomoyuki Saga, Tetsuyuki Igarashi, Kentaro Wakasa, Ikumi Kasahara, Yukari Takeda, Keisuke Yamaguchi, Akio Shigematsu, Mutsumi Takahata, Katsuya Fujimoto, Yoshihito Haseyama, Takahiro Nagashima, Hajime Sakai, Yasutaka Kakinoki, Mitsutoshi Kurosawa, Isao Yokota, Takanori Teshima

https://doi.org/10.3324/haematol.2023.284841

Azacitidine as epigenetic priming for chemotherapy is safe and well-tolerated in infants with newly diagnosed KMT2A-rearranged acute lymphoblastic leukemia: Children’s Oncology Group trial AALL15P1 (490 Online Views)

Erin M. Guest, John A. Kairalla, Meenakshi Devidas, Emily Hibbitts, Andrew J. Carroll, Nyla A. Heerema, Holly R. Kubaney, Margaret A. August, Sidharth Ramesh, Byunggil Yoo, Midhat S. Farooqi, Melinda G. Pauly, Daniel S. Wechsler, Rodney R. Miles, Joel M. Reid, Cynthia D. Kihei, Lia Gore, Elizabeth A. Raetz, Stephen P. Hunger, Mignon L. Loh, Patrick A. Brown

https://doi.org/10.3324/haematol.2024.285158

Letters to the Editor

PD-1 blockade and allogeneic hematopoietic stem cell transplantation in Hodgkin lymphoma, a matter of time: a national study on behalf of the Société Francophone de Greffe de Moelle et de Thérapie Cellulaire (331 Online Views)

Eleonore Kaphan, Francois Bettega, Nicolas Vallet, Nathalie Fegueux, Marie Robin, Ali Bazarbachi, Stephanie Nguyen, David Beauvais, Edouard Forcade, Maria Carolina Montes De Oca, Raynier Devillier, Patrice Chevallier, Michael Loschi, Anne Huynh, Jacques-Olivier Bay, Marie-Therese Rubio, Felipe Suarez, Sylvie Francois, Xavier Poire, Nathalie Contentin, Deborah Desmier, Amandine Charbonnier, Jerome Cornillon, Sylvain Chantepie, Pascal Turlure, Claude-Eric Bulabois, David Michonneau, Alban Villate; SFGM-TC (Collaborative Group)

https://doi.org/10.3324/haematol.2024.284968

Changes in sex-specific incidence of lymphoid neoplasms across the lifespan (200 Online Views)

Bryan Valcarcel, Sara J. Schonfeld, Sarah S. Jackson, Graça M. Dores, Martha S. Linet, Lindsay M. Morton

https://doi.org/10.3324/haematol.2024.285281

Soluble SLAMF7 is generated by alternative splicing in multiple myeloma cells (435 Online Views)

Jiro Kikuchi, Mitsuo Hori, Naoki Osada, Sae Matsuoka, Atsushi Suzuki, Satoshi Kakugawa, Hiroshi Yasui, Takeshi Harada, Hirofumi Tenshin, Masahiro Abe, Hideki Nakasone, Yusuke Furukawa

https://doi.org/10.3324/haematol.2024.285368

De-escalation of corticosteroids and clonal remission in UBA1 mutation-driven VEXAS syndrome with 5-azacytidine (425 Online Views)

Roochi Trikha, Kar Lok Kong, James Galloway, Tanya N. Basu, Lynn Quek, Jamie Wilson, Louise Gamble, Henna Wong, Steven Best, Austin Kulasekararaj

https://doi.org/10.3324/haematol.2024.285519

Jun 6, 2024

Articles

Epstein-Barr Virus and immune status imprint the immunogenomics of non-Hodgkin lymphomas occurring in immune-suppressed environments (678 Online Views)

Marine Baron, Karim Labreche, Marianne Veyri, Nathalie Désiré, Amira Bouzidi, Fatou Seck-Thiam, Frédéric Charlotte, Alice Rousseau, Véronique Morin, Cécilia Nakid-Cordero, Baptiste Abbar, Alberto Picca, Marie Le Cann, Noureddine Balegroune, Nicolas Gauthier, Ioannis Theodorou, Mehdi Touat, Véronique Morel, Franck Bielle, Assia Samri, Agusti Alentorn, Marc Sanson, Damien Roos-Weil, Corinne Haioun, Elsa Poullot, Anne Langlois de Septenville, Frédéric Davi, Amélie Guihot, Pierre-Yves Boelle, Véronique Leblond, Florence Coulet, Jean-Philippe Spano, Sylvain Choquet, Brigitte Autran; IDeATIon study group (Collaborative Group)

https://doi.org/10.3324/haematol.2023.284332

IKZF1 gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia (524 Online Views)

Britt M. T. Vervoort, Miriam Butler, Kari J.T. Grünewald, Dorette S. van Ingen Schenau, Trisha M. Tee, Luc Lucas, Alwin D. R. Huitema, Judith M. Boer, Beat C. Bornhauser, Jean-Pierre Bourquin, Peter M. Hoogerbrugge, Vincent H.J. van der Velden, Roland P. Kuiper, Laurens T. van der Meer, Frank N. van Leeuwen

https://doi.org/10.3324/haematol.2023.284357

Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma (804 Online Views)

Nicholas Davies, Tegan Francis, Ceri Oldreive, Maria Azam, Jordan Wilson, Philip J. Byrd, Megan Burley, Archana Sharma-Oates, Peter Keane, Sael Alatawi, Martin R. Higgs, Zbigniew Rudzki, Maha Ibrahim, Tracey Perry, Angelo Agathanggelou, Anne-Marie Hewitt, Edward Smith, Constanze Bonifer, Mark O’Connor, Josep V. Forment, Paul G. Murray, Eanna Fennell, Gemma Kelly, Catherine Chang, Grant S. Stewart, Tatjana Stankovic, Marwan Kwok, Alexander Malcolm Taylor

https://doi.org/10.3324/haematol.2023.284404

Asciminib stands out as the superior tyrosine kinase inhibitor to combine with anti-CD20 monoclonal antibodies for the treatment of CD20+ Philadelphia-positive B-cell precursor acute lymphoblastic leukemia in preclinical models (677 Online Views)

Krzysztof Domka, Agnieszka Dąbkowska, Martyna Janowska, Zuzanna Urbańska, Agata Pastorczak, Magdalena Winiarska, Klaudyna Fidyt, Mieszko Lachota, Elżbieta Patkowska, Łukasz Sędek, Bartosz Perkowski, Jaromir Hunia, Justyna Jakubowska, Beata Krzymieniewska, Ewa Lech-Marańda, Wojciech Młynarski, Tomasz Szczepański, Małgorzata Firczuk

https://doi.org/10.3324/haematol.2023.284853

Impact of genetic alterations on central nervous system progression of primary vitreoretinal lymphoma (505 Online Views)

Kota Yoshifuji, Daichi Sadato, Takashi Toya, Yotaro Motomura, Chizuko Hirama, Hiroshi Takase, Kouhei Yamamoto, Yuka Harada, Takehiko Mori, Toshikage Nagao

https://doi.org/10.3324/haematol.2023.284953

Factor VIII promotes angiogenesis and vessel stability regulating extracellular matrix proteins (399 Online Views)

Cristina Olgasi, Alessia Cucci, Ivan Molineris, Simone Assanelli, Francesca Anselmi, Chiara Borsotti, Chiara Sgromo, Andrea Lauria, Simone Merlin, Gillian E. Walker, Salvatore Oliviero, Antonia Follenzi

https://doi.org/10.3324/haematol.2024.285089

Superior outcomes and high-risk features with carfilzomib, lenalidomide, and dexamethasone combination therapy for patients with relapsed and refractory multiple myeloma: Results of the multicenter KMMWP2201 study (608 Online Views)

Ji Hyun Lee, Jimin Choi, Chang-Ki Min, Sung-Soo Park, Jae-Cheol Jo, Yoo Jin Lee, Jin Seok Kim, Hyeon-Seok Eom, Jongheon Jung, Joon Ho Moon, Hee Jeong Cho, Myung-won Lee, Sung-Soo Yoon, Ja Min Byun, Jae Hoon Lee, Je-Jung Lee, Sung-Hoon Jung, Ho-Jin Shin, Do Young Kim, Jun Ho Yi, Seung-Shin Lee, Young Rok Do, Dok Hyun Yoon, Hyungwoo Cho, Won Sik Lee, Ho Sup Lee, Jieun Uhm, Hyo Jung Kim, Hee Ryeong Jang, Sung-Hyun Kim, Kihyun Kim

https://doi.org/10.3324/haematol.2024.285534

Letters to the Editor

Long-term efficacy and safety of tucidinostat in patients with relapsed or refractory peripheral T-cell lymphoma: final analysis of phase IIb results (770 Online Views)

Shinya Rai, Won Seog Kim, Kiyoshi Ando, Ilseung Choi, Koji Izutsu, Norifumi Tsukamoto, Dai Maruyama, Kunihiro Tsukasaki, Junya Kuroda, Jun Ando, Michihiro Hidaka, Youngil Koh, Hisashi Kato, Toshiki Uchida, Deok Hwan Yang, Kenji Ishitsuka, Kenichi Ishizawa, Jin Seok Kim, Hong Ghi Lee, Hironobu Minami, Hyeon Seok Eom, Mitsutoshi Kurosawa, Jae Hoon Lee, Jong Seok Lee, Won Sik Lee, Hirokazu Nagai, Takero Shindo, Dok Hyun Yoon, Shinichiro Yoshida, Mireille Gillings, Hiroshi Onogi, Kensei Tobinai

https://doi.org/10.3324/haematol.2023.283992

Comments

May 30, 2024

Articles

The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival (549 Online Views)

Vesna S. Stanulović, Shorog Al Omair, Michelle A.C. Reed, Jennie Roberts, Sandeep Potluri, Taylor Fulton-Ward, Nancy Gudgeon, Emma L. Bishop, Juliette Roels, Tracey A. Perry, Sovan Sarkar, Guy Pratt, Tom Taghon, Sarah Dimeloe, Ulrich L. Günther, Christian Ludwig, Maarten Hoogenkamp

https://doi.org/10.3324/haematol.2023.283471

Deep phenotyping of nodal T-cell lymphomas reveals immune alterations and therapeutic targets (492 Online Views)

Pierre Stephan, Jimmy Perrot, Allison Voisin, Maud Barbery, Thibault Andrieu, Maxime Grimont, Julie Caramel, Mathilde Bardou, Garance Tondeur, Edoardo Missiaglia, Philippe Gaulard, François Lemmonier, Laurence de Leval, Emmanuel Bachy, Pierre Sujobert, Laurent Genestier, Alexandra Traverse-Glehen, Yenkel Grinberg-Bleyer

https://doi.org/10.3324/haematol.2023.284448

Mucosal-associated invariant T cells are functionally impaired in pediatric and young adult patients following allogeneic hematopoietic stem cell transplantation and their recovery correlates with clinical outcomes (740 Online Views)

Federica Galaverna, Sara Flamini, Carmen Dolores De Luca, Ilaria Pili, Emilia Boccieri, Francesca Benini, Francesco Quagliarella, Chiara Rosignoli, Marco Rosichini, Shirley Genah, Marialuigia Catanoso, Antonella Cardinale, Gabriele Volpe, Marianna Coccetti, Angela Pitisci, Giuseppina Li Pira, Roberto Carta, Barbarella Lucarelli, Francesca Del Bufalo, Valentina Bertaina, Marco Becilli, Daria Pagliara, Mattia Algeri, Pietro Merli, Franco Locatelli, Enrico Velardi

https://doi.org/10.3324/haematol.2023.284649

Management of complications of chimeric antigen receptor T-cell therapy: a report by the European Society of Blood and Marrow Transplantation (922 Online Views)

Olaf Penack, Christophe Peczynski, William Boreland, Daniel Wolff, Ivan Moiseev, Hélène Schoemans, Christian Koenecke, Charlotte Graham, Zinaida Peric

https://doi.org/10.3324/haematol.2023.284810

Prognostic impact of ‘multi-hit’ versus ‘single hit’ TP53 alteration in patients with acute myeloid leukemia: results from the Consortium on Myeloid Malignancies and Neoplastic Diseases (1077 Online Views)

Talha Badar, Ahmad Nanaa, Ehab Atallah, Rory M. Shallis, Emily C. Craver, Zhuo Li, Aaron D. Goldberg, Antoine N. Saliba, Anand Patel, Jan P. Bewersdorf, Adam Duvall, Madelyn Burkart, Danielle Bradshaw, Yasmin Abaza, Maximilian Stahl, Neil Palmisiano, Guru Subramanian Guru Murthy, Amer M. Zeidan, Vamsi Kota, Mrinal M. Patnaik, Mark R. Litzow

https://doi.org/10.3324/haematol.2024.285000

LILRB4 represents a promising target for immunotherapy by dual targeting tumor cells and myeloid-derived suppressive cells in multiple myeloma (1075 Online Views)

Lixin Gong, Hao Sun, Lanting Liu, Xiyue Sun, Teng Fang, Zhen Yu, Weiwei Sui, Jingyu Xu, Tingyu Wang, Fangshuo Feng, Lei Lei, Wei Rui, Yuxuan Liu, Xueqiang Zhao, Gang An, Xin Lin, Lugui Qiu, Mu Hao

https://doi.org/10.3324/haematol.2024.285099

The role of PALLD-STAT3 interaction in megakaryocyte differentiation and thrombocytopenia treatment (547 Online Views)

Guoming Li, Haojie Jiang, Lingbin Wang, Tingting Liang, Chen Ding, Mina Yang, Yingzhi Shen, Min Xin, Lin Zhang, Jing Dai, Xueqing Sun, Xuejiao Chen, Junling Liu, Yanyan Xu

https://doi.org/10.3324/haematol.2024.285242

Letters to the Editor

Validation and molecular integration of the RR6 model to predict survival after 6 months of therapy with ruxolitinib (430 Online Views)

Giacomo Coltro, Giulio Capecchi, Margherita Maffioli, Francesco Mannelli, Barbara Mora, Alessandro Atanasio, Alessandra Iurlo, Chiara Maccari, Mirko Farina, Elena Nacca, Marianna Caramella, Leonardo Signori, Miriam Borella, Lorenza Bertù, Maria Esposito, Paola Guglielmelli, Francesco Passamonti, Alessandro Maria Vannucchi

https://doi.org/10.3324/haematol.2024.285098

Infrequent fractures and resilient bone mineral density: bone health in patients with Fanconi anemia (241 Online Views)

Jane Koo, Jonathan C. Howell, Lindsey Hornung, Anthony Sabulski, Parinda A. Mehta, Stella M. Davies, Kasiani C. Myers

https://doi.org/10.3324/haematol.2024.285612

Case Reports

Treatment strategies for progressive immune effector cell-associated hemophagocytic lymphohistiocytosis-like syndrome: case series (491 Online Views)

Jack J. Scala, Michael J. Eckrich, Keagan Lipak, Bonnie Yates, Constance Yuan, Hao-Wei Wang, Saurabh Dahiya, Jan-Inge Henter, Jeffrey S. Huo, Matthew J. Frank, Nirali N. Shah

https://doi.org/10.3324/haematol.2023.284784

Late-onset NPM1 mutation in a MYC-amplified relapsed/refractory acute myeloid leukemia patient treated with gemtuzumab ozogamicin and glasdegib (517 Online Views)

Sonia Jaramillo, Michael Scherer, Chelsea Szu-Tu, Sergi Beneyto-Calabuig, Carsten Müller-Tidow, Richard F. Schlenk, Michael Hundemer, Lars Velten, Caroline Pabst

https://doi.org/10.3324/haematol.2023.284922

Myeloid neoplasm with histiocytosis and spleen tyrosine kinase fusion responds to fostamatinib (454 Online Views)

Zachary Risch, Benjamin H. Kaffenberger, Catherine G. Chung, Eric Samorodnitsky, Emily L. Hoskins, Thuy Dao, Amy Smith, Sarah A. Wall, Jonathan Brammer, Julie W. Reeser, Michele R. Wing, Julia F. Hopkins, Lee A. Albacker, Lynne V. Abruzzo, Caprice D. Eisele, Aharon G. Freud, Sameek Roychowdhury, Katherine E. Walsh

https://doi.org/10.3324/haematol.2024.285146

May 23, 2024

Review Articles

Articles

Checkpoint inhibition enhances cell contacts between CD4+ T cells and Hodgkin-Reed-Sternberg cells of classic Hodgkin lymphoma (405 Online Views)

Kübra Yadigaroglu, Sonja Scharf, Steffen Gretser, Hendrik Schäfer, Aresu Sadeghi Shoreh Deli, Andreas G. Loth, Hasmik Yegoryan, Roland Schmitz, Emmanuel Donnadieu, Martin-Leo Hansmann, Sylvia Hartmann

https://doi.org/10.3324/haematol.2023.284512

Use of defibrotide in COVID-19 pneumonia: comparison of a phase II study and a matched real-world cohort control (470 Online Views)

Annalisa Ruggeri, Francesco Corrado, Antonio Voza, Lee-Jen Wei, Gloria Catalano, Carmine Liberatore, Rosamaria Nitti, Carlo Fedeli, Alessandro Bruno, Eleonora Calabretta, Fabio Giglio, Fabio Sciutti, Francesca Lunghi, Giovanni Landoni, Alessio Aghemo, Massimo Iacobelli, Patrizia Rovere Querini, Paul G. Richardson, Andrea Assanelli, Jacopo Peccatori, Fabio Ciceri, Carmelo Carlo-Stella

https://doi.org/10.3324/haematol.2024.285345

Comments

May 16, 2024

Editorials
Article

Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies (902 Online Views)

Melissa Krystel-Whittemore, Kseniya Petrova-Drus, Ryan N. Ptashkin, Mark D. Ewalt, JinJuan Yao, Ying Liu, Menglei Zhu, Jamal Benhamida, Benjamin Durham, Jyoti Kumar, Khedoudja Nafa, Iwona Kiecka, Anita S. Bowman, Erika Gedvilaite, Jacklyn Casanova, Yun-Te Lin, Abhinita S. Mohanty, Satshil Rana, Anoop Balakrishnan Rema, Ivelise Rijo, Nelio Chaves, Paulo Salazar, Anita Yun, Sean Lachhander, Wei Wang, Mohammad S. Haque, Wenbin Xiao, Mikhail Roshal, Sergio Giralt, Gilles Salles, Raajit Rampal, Eytan M. Stein, Miguel-Angel Perales, Steven Horwitz, Ann Jakubowski, Doris Ponce, Alina Markova, Ozge Birsoy, Diana Mandelker, Simon Mantha, Ahmet Dogan, Ryma Benayed, Marc Ladanyi, Michael F. Berger, A. Rose Brannon, Ahmet Zehir, Chad Vanderbilt, Maria E. Arcila

https://doi.org/10.3324/haematol.2024.285054

Editorials
Article

Stroke without cerebral arteriopathy in sickle cell disease children: causes and treatment (510 Online Views)

Sarah Liane Linguet, Suzanne Verlhac, Florence Missud, Laurent Holvoet-Vermaut, Valentine Brousse, Ghislaine Ithier, Alexandra Ntorkou, Emmanuelle Lesprit, Malika Benkerrou, Manoëlle Kossorotoff, Berengere Koehl

https://doi.org/10.3324/haematol.2023.283773

Editorials

Editorials
Letter to the Editor

Expedited evaluation of hereditary hematopoietic malignancies in the setting of stem cell transplantation (679 Online Views)

Gregory W. Roloff, Satyajit Kosuri, Mariam T. Nawas, Adam S. DuVall, Anand A. Patel, Peter A. Riedell, Olatoyosi Odenike, Wendy Stock, Richard A. Larson, Michael R. Bishop, Emma Nunley, Lucy A. Godley, Feighanne Hathaway, Daniela del Gaudio, Soma Das, Lorraine E. Canham, Michael W. Drazer

https://doi.org/10.3324/haematol.2023.284584

Comments

May 9, 2024

Editorials
Article

HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells (747 Online Views)

Tamara De Vos, Nicole Oatman, Lena Boehme, Tom Putteman, Imke Velghe, Yana Van Droogenbroeck, Stijn De Munter, Michaela Cesnekova, Filip Van Nieuwerburgh, Bart Vandekerckhove, Jan Philippe, Tom Taghon

https://doi.org/10.3324/haematol.2023.283432

Editorials
Article

Gut microbiome alterations at acute myeloid leukemia diagnosis are associated with muscle weakness and anorexia (912 Online Views)

Sarah A. Pötgens, Violaine Havelange, Sophie Lecop, Fuyong Li, Audrey M. Neyrinck, Florence Bindels, Nathalie Neveux, Jean-Baptiste Demoulin, Ine Moors, Tessa Kerre, Johan Maertens, Jens Walter, Hélène Schoemans, Nathalie M. Delzenne, Laure B. Bindels

https://doi.org/10.3324/haematol.2023.284138

Articles

Targeting CD19-positive lymphomas with the antibody-drug conjugate loncastuximab tesirine: preclinical evidence as single agent and in combination therapy (926 Online Views)

Chiara Tarantelli, David Wald, Nicolas Munz, Filippo Spriano, Alessio Bruscaggin, Eleonora Cannas, Luciano Cascione, Eugenio Gaudio, Alberto J. Arribas, Shivaprasad Manjappa, Gaetanina Golino, Lorenzo Scalise, Maria Teresa Cacciapuoti, Emanuele Zucca, Anastasios Stathis, Giorgio Inghirami, Patrick H. van Berkel, Davide Rossi, Paolo F. Caimi, Francesca Zammarchi, Francesco Bertoni

https://doi.org/10.3324/haematol.2023.284197

The diversity of the microbiome impacts chronic lymphocytic leukemia development in mice and humans (646 Online Views)

Tereza Faitova, Mariana Coelho, Caspar da Cunha-Bang, Selcen Ozturk, Ece Kartal, Peer Bork, Martina Seiffert, Carsten U. Niemann

https://doi.org/10.3324/haematol.2023.284693

Continuous and differential improvement in worldwide access to hematopoietic cell transplantation: activity has doubled in a decade with a notable increase in unrelated and non-identical related donors (733 Online Views)

Yoshiko Atsuta, Helen Baldomero, Daniel Neumann, Anna Sureda, Jakob D. DeVos, Minako Iida, Amado Karduss, Duncan Purtill, Alaa M. Elhaddad, Nosa G. Bazuaye, Carmem Bonfim, Rafael de la Camara, Naeem A. Chaudhri, Fabio Ciceri, Cinthya Correa, Cristobal Frutos, Sebastian Galeano, Laurent Garderet, Oscar Gonzalez-Ramella, Raffaella Greco, Nada Hamad, Mette D. Hazenberg, Mary M. Horowitz, Krzysztof Kalwak, Bor-Sheng Ko, Yoshihisa Kodera, Mickey BC Koh, Kaiyan Liu, Donal P. McLornan, Joon Ho Moon, Benedicte Neven, Shinichiro Okamoto, Marcelo C Pasquini, Jakob R. Passweg, Kristjan Paulson, Damiano Rondelli, Annalisa Ruggeri, Adriana Seber, John A. Snowden, Alok Srivastava, Jeff Szer, Daniel Weisdorf, Nina Worel, Hildegard Greinix, Wael Saber, Mahmoud Aljurf, Dietger Niederwieser

https://doi.org/10.3324/haematol.2024.285002

Case Reports

A case of familial donor-derived acute myeloid leukemia with underlying pre-leukemic mutations (306 Online Views)

Luca Vincenzo Cappelli, Clara Minotti, Manja Meggendorfer, Marietta Truger, Torsten Haferlach, Cristina Mecucci, Caterina Matteucci, Caterina Alati, Anna Paola Iori, Maurizio Martelli, Robin Foà

https://doi.org/10.3324/haematol.2024.285156

May 2, 2024

Articles

Treatment of chronic-phase chronic myeloid leukemia in patients randomized to dasatinib or imatinib after suboptimal responses to three months of imatinib therapy: final 5-year results from DASCERN (807 Online Views)

Jorge E. Cortes, Qian Jiang, Jianxiang Wang, Jianyu Weng, Huanling Zhu, Xiaoli Liu, Andreas Hochhaus, Dong-Wook Kim, Jerald Radich, Michael Savona, Patricia Martin-Regueira, Oumar Sy, Giuseppe Saglio

https://doi.org/10.3324/haematol.2023.283428

Outcomes and genetic dynamics of acute myeloid leukemia at first relapse (1269 Online Views)

Alex Bataller, Hagop Kantarjian, Alexandre Bazinet, Tapan Kadia, Naval Daver, Courtney D. DiNardo, Gautam Borthakur, Sanam Loghavi, Keyur Patel, Guilin Tang, Koji Sasaki, Nicholas J. Short, Musa Yilmaz, Ghayas C. Issa, Yesid Alvarado, Guillermo Montalban-Bravo, Abhishek Maiti, Hussein A. Abbas, Koichi Takahashi, Sherry Pierce, Elias Jabbour, Guillermo Garcia-Manero, Farhad Ravandi

https://doi.org/10.3324/haematol.2024.285057

Letters to the Editor

Soluble urokinase plasminogen activator receptor is associated with kidney disease and its progression in sickle cell anemia (358 Online Views)

Rima S. Zahr, Sara R. Rashkin, Maria Armila Ruiz, Laila Elsherif, Guohui Ren, Guadalupe Salas, Kenneth I. Ataga, Victor R. Gordeuk, Jeffrey Lebensburger, Xu Zhang, Santosh L. Saraf

https://doi.org/10.3324/haematol.2023.284920

Apr 24, 2024

Editorials
Article

Impact and utility of follicular lymphoma GELF criteria in routine care: an Australasian Lymphoma Alliance study (744 Online Views)

Allison Barraclough, Shivam Agrawal, Dipti Talaulikar, Geoffrey Chong, Edward Yoo, Chan Y. Cheah, Nunzio Franco, Bianca Nguyen, Howard Mutsando, Fatima Tahir, Judith Trotman, Jing Huang, Colm Keane, Mitchel Lincoln, Tara Cochrane, Anna M. Johnston, Michael Dickinson, Stephen Opat, Zoe K. McQuilten, Erica M. Wood, Gayathri St George, Eliza A. Hawkes

https://doi.org/10.3324/haematol.2023.284538

Editorials

Apr 18, 2024

Editorials
Article

Small extracellular vesicles derived from acute myeloid leukemia cells promote leukemogenesis by transferring miR-221-3p (903 Online Views)

Mengyu Li, Guohuan Sun, Jinlian Zhao, Shuangshuang Pu, Yanling Lv, Yifei Wang, Yapu Li, Xiangnan Zhao, Yajie Wang, Shangda Yang, Tao Cheng, Hui Cheng

https://doi.org/10.3324/haematol.2023.284145

Apr 11, 2024

Articles

Letters to the Editor

Expedited evaluation of hereditary hematopoietic malignancies in the setting of stem cell transplantation (679 Online Views)

Gregory W. Roloff, Satyajit Kosuri, Mariam T. Nawas, Adam S. DuVall, Anand A. Patel, Peter A. Riedell, Olatoyosi Odenike, Wendy Stock, Richard A. Larson, Michael R. Bishop, Emma Nunley, Lucy A. Godley, Feighanne Hathaway, Daniela del Gaudio, Soma Das, Lorraine E. Canham, Michael W. Drazer

https://doi.org/10.3324/haematol.2023.284584

Apr 4, 2024

Articles

HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells (747 Online Views)

Tamara De Vos, Nicole Oatman, Lena Boehme, Tom Putteman, Imke Velghe, Yana Van Droogenbroeck, Stijn De Munter, Michaela Cesnekova, Filip Van Nieuwerburgh, Bart Vandekerckhove, Jan Philippe, Tom Taghon

https://doi.org/10.3324/haematol.2023.283432

Soluble B-cell maturation antigen in lacrimal fluid as a potential biomarker and mediator of keratopathy in multiple myeloma (982 Online Views)

Umair Munawar, Johanna Theuersbacher, Maximilian J. Steinhardt, Xiang Zhou, Seungbin Han, Silvia Nerreter, Cornelia Vogt, Shilpa Kurian, Thorsten Keller, Ann-Katrin Regensburger, Eva Teufel, Julia Mersi, Max Bittrich, Franziska Seifert, Malik S. Haider, Leo Rasche, Jost Hillenkamp, Hermann Einsele, Daniel Kampik, K. Martin Kortüm, Johannes M. Waldschmidt

https://doi.org/10.3324/haematol.2024.285205

Letters to the Editor

Universal germline genetic testing in patients with hematologic malignancies using DNA isolated from nail clippings (578 Online Views)

Ozge Ceyhan-Birsoy, Elise Fiala, Satshil Rana, Margaret Sheehan, Jennifer Kennedy, Zarina Yelskaya, Vikas Rai, Yirong Li, Ciyu Yang, Donna Wong, Ivelise Rijo, Jacklyn Casanova, Joshua Somar, Nikita Mehta, Hyeonjin Park, Silvana Ostafi, Kanika Arora, Angelika Padunan, Mark D. Ewalt, Umut Aypar, Panieh Terraf, Maksym Misyura, Sofia Haque, Gerald G. Behr, Tamanna Haque, Maria Sulis, Mark B. Geyer, Christopher Forlenza, Meghan C. Thompson, Maria Carlo, Alicia Latham, Ying Liu, Ahmet Zehir, Rose Brannon, Michael Berger, Luis A Diaz Jr, Ahmet Dogan, Marc Ladanyi, Kseniya Petrova-Drus, Khedoudja Nafa, Kenneth Offit, Maria Arcila, Zsofia K. Stadler, Michael F. Walsh, Diana Mandelker

https://doi.org/10.3324/haematol.2024.285055

Mar 28, 2024

Articles

Gut microbiome alterations at acute myeloid leukemia diagnosis are associated with muscle weakness and anorexia (912 Online Views)

Sarah A. Pötgens, Violaine Havelange, Sophie Lecop, Fuyong Li, Audrey M. Neyrinck, Florence Bindels, Nathalie Neveux, Jean-Baptiste Demoulin, Ine Moors, Tessa Kerre, Johan Maertens, Jens Walter, Hélène Schoemans, Nathalie M. Delzenne, Laure B. Bindels

https://doi.org/10.3324/haematol.2023.284138

Letters to the Editor

Mar 14, 2024

Articles

Stroke without cerebral arteriopathy in sickle cell disease children: causes and treatment (510 Online Views)

Sarah Liane Linguet, Suzanne Verlhac, Florence Missud, Laurent Holvoet-Vermaut, Valentine Brousse, Ghislaine Ithier, Alexandra Ntorkou, Emmanuelle Lesprit, Malika Benkerrou, Manoëlle Kossorotoff, Berengere Koehl

https://doi.org/10.3324/haematol.2023.283773

Mar 7, 2024

Articles

Cell-free DNA from nail clippings as source of normal control for genomic studies in hematologic malignancies (902 Online Views)

Melissa Krystel-Whittemore, Kseniya Petrova-Drus, Ryan N. Ptashkin, Mark D. Ewalt, JinJuan Yao, Ying Liu, Menglei Zhu, Jamal Benhamida, Benjamin Durham, Jyoti Kumar, Khedoudja Nafa, Iwona Kiecka, Anita S. Bowman, Erika Gedvilaite, Jacklyn Casanova, Yun-Te Lin, Abhinita S. Mohanty, Satshil Rana, Anoop Balakrishnan Rema, Ivelise Rijo, Nelio Chaves, Paulo Salazar, Anita Yun, Sean Lachhander, Wei Wang, Mohammad S. Haque, Wenbin Xiao, Mikhail Roshal, Sergio Giralt, Gilles Salles, Raajit Rampal, Eytan M. Stein, Miguel-Angel Perales, Steven Horwitz, Ann Jakubowski, Doris Ponce, Alina Markova, Ozge Birsoy, Diana Mandelker, Simon Mantha, Ahmet Dogan, Ryma Benayed, Marc Ladanyi, Michael F. Berger, A. Rose Brannon, Ahmet Zehir, Chad Vanderbilt, Maria E. Arcila

https://doi.org/10.3324/haematol.2024.285054

Impact and utility of follicular lymphoma GELF criteria in routine care: an Australasian Lymphoma Alliance study (744 Online Views)

Allison Barraclough, Shivam Agrawal, Dipti Talaulikar, Geoffrey Chong, Edward Yoo, Chan Y. Cheah, Nunzio Franco, Bianca Nguyen, Howard Mutsando, Fatima Tahir, Judith Trotman, Jing Huang, Colm Keane, Mitchel Lincoln, Tara Cochrane, Anna M. Johnston, Michael Dickinson, Stephen Opat, Zoe K. McQuilten, Erica M. Wood, Gayathri St George, Eliza A. Hawkes

https://doi.org/10.3324/haematol.2023.284538

Small extracellular vesicles derived from acute myeloid leukemia cells promote leukemogenesis by transferring miR-221-3p (903 Online Views)

Mengyu Li, Guohuan Sun, Jinlian Zhao, Shuangshuang Pu, Yanling Lv, Yifei Wang, Yapu Li, Xiangnan Zhao, Yajie Wang, Shangda Yang, Tao Cheng, Hui Cheng

https://doi.org/10.3324/haematol.2023.284145

Perspective Articles

Feb 22, 2024

Editorials
Article

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma (1467 Online Views)

Stien De Coninck, Renate De Smedt, Beatrice Lintermans, Lindy Reunes, Hansen J. Kosasih, Alexandra Reekmans, Lauren M. Brown, Nadine Van Roy, Bruno Palhais, Juliette Roels, Malaika Van der Linden, Jo Van Dorpe, Panagiotis Ntziachristos, Frederik W. van Delft, Marc R. Mansour, Tim Pieters, Tim Lammens, Barbara De Moerloose, Charles E. de Bock, Steven Goossens, Pieter Van Vlierberghe

https://doi.org/10.3324/haematol.2023.283981

Feb 15, 2024

Guidelines

Approaches for bridging therapy prior to chimeric antigen receptor T cells for relapsed/refractory acute lymphoblastic B-lineage leukaemia in children and young adults (885 Online Views)

Tobias Feuchtinger, Peter Bader, Marion Subklewe, Maike Breidenbach, Semjon Willier, Markus Metzler, Nicola Gökbuget, Julia Hauer, Fabian Müller, Paul-Gerhardt Schlegel, Michael Frühwald, Christoph Schmid, Anja Troeger, Claudia Baldus, Roland Meisel, Annette Künkele, Max Topp, Jean-Pierre Bourquin, Gunnar Cario, Arend von Stackelberg, Christina Peters

https://doi.org/10.3324/haematol.2023.283780

Feb 1, 2024

Articles

CD74 is expressed in a subset of pediatric acute myeloid leukemia patients and is a promising target for therapy: a report from the Children’s Oncology Group (735 Online Views)

Andrew J. Menssen, Chad A. Hudson, Todd Alonzo, Robert Gerbing, Laura Pardo, Amanda Leonti, Jacqueline A. Cook, Fan-Chi Hsu, Loren L. Lott, Fangyan Dai, Collette Fearing, Keely Ghirardelli, Tiffany Hylkema, Katherine Tarlock, Keith R. Loeb, Edward A. Kolb, Todd Cooper, Jessica Pollard, Denise A. Wells, Michael R. Loken, Richard Aplenc, Soheil Meshinchi, Lisa Eidenschink Brodersen

https://doi.org/10.3324/haematol.2023.283757

Jan 18, 2024

Articles

Pediatric-inspired regimen for adolescent and adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia: a prospective study from China (955 Online Views)

Xiaoyuan Gong, Qiuyun Fang, Runxia Gu, Shaowei Qiu, Kaiqi Liu, Dong Lin, Chunlin Zhou, Guangji Zhang, Benfa Gong, Yuntao Liu, Yan Li, Bingcheng Liu, Ying Wang, Hui Wei, Yingchang Mi, Jianxiang Wang

https://doi.org/10.3324/haematol.2023.284228

Jan 4, 2024

Articles

Inotuzumab ozogamicin combined with chemotherapy in pediatric B-cell precursor CD22+ acute lymphoblastic leukemia: results of the phase IB ITCC-059 trial (1172 Online Views)

Edoardo Pennesi, Erica Brivio, Anneke C. J. Ammerlaan, Yilin Jiang, Vincent H. J. van der Velden, H. Berna Beverloo, Barbara Sleight, Franco Locatelli, Benoit Brethon, Claudia Rossig, Gernot Engstler, Anna Nilsson, Benedicte Bruno, Arnaud Petit, Bella Bielorai, Carmelo Rizzari, Fanny Rialland, Alba Rubio-San-Simón, Francisco J. Bautista Sirvent, Cristina Diaz-de-Heredia, Susana Rives, Christian M. Zwaan

https://doi.org/10.3324/haematol.2023.284409

Dec 14, 2023

Guidelines

Nov 16, 2023

Articles

Pilot study of lung cancer screening for survivors of Hodgkin lymphoma (545 Online Views)

Rachel Broadbent, Philip Crosbie, Christopher J. Armitage, Ben Taylor, Sean Tenant, Joseph Mercer, John Radford, Kim Linton

https://doi.org/10.3324/haematol.2023.283287

Aug 19, 2021

Errata Corrige

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma (3713 Online Views)

Johannes Duell, Kami J. Maddocks, Eva González-Barca, Wojciech Jurczak, Anna Marina Liberati, Sven de Vos, Zsolt Nagy, Aleš Obr, Gianluca Gaidano, Pau Abrisqueta, Nagesh Kalakonda, Marc André, Martin Dreyling, Tobias Menne, Olivier Tournilhac, Marinela Augustin, Andreas Rosenwald, Maren Dirnberger-Hertweck, Johannes Weirather, Sumeet Ambarkhane, Gilles Salles

https://doi.org/10.3324/haematol.2021.279802

May 10, 2018

Articles

GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells (1425 Online Views)

Beibei Zhang, Pilar Ayuda Durán, Laure Piechaczyk, Yngvar Fløisand, Mireia Mayoral Safont Safont, Ida Tveit Karlsen, Zina Fandalyuk, Dagim Tadele, Pepijn van Mierlo, Alexander D. Rowe, Joseph M. Robertson, Bjørn Tore Gjertsen, Emmet McCormack, Jorrit M. Enserink, Bjørn Tore Gjertsen Group, Emmet McCormack Group

https://doi.org/10.3324/haematol.2018.189399