Early view

Aug 4, 2022

Editorials
Letter to the Editor

Morbidity and mortality of sickle cell disease patients is unaffected by splenectomy: evidence from 3 decades follow-up in a high-income setting (52 Online Views)

Valeria Maria Pinto, Barbara Gianesin, Frédéric B. Piel, Filomena Longo, Paolo Rigano, Alessandra Quota, Vincenzo Spadola, Giovanna Graziadei, Filippo Mazzi, Maria Domenica Cappellini, Aurelio Maggio, Antonio Piga, Lucia De Franceschi, Gian Luca Forni

https://doi.org/10.3324/haematol.2022.280815

Articles

Early expression of CD94 and loss of CD96 on CD8+ T cells after allogeneic SCT is predictive of subsequent relapse and survival (183 Online Views)

Kriti Verma, Wayne Croft, Hayden Pearce, Jianmin Zuo, Christine Stephens, Jane Nunnick, Francesca AM Kinsella, Ram Malladi, Paul Moss

https://doi.org/10.3324/haematol.2021.280497

Clinical and biological impact of ATP-binding cassette transporter activity in adult acute myeloid leukemia (61 Online Views)

Elise Sourdeau, Ludovic Suner, Mara Memoli, Alexis Genthon, Frédéric Feger, Lou Soret, Nasséra Abermil, Laurence Heuberger, Chrystele Bilhou-Nabera, Hélène Guermouche, Fabrizia Favale, Simona Lapusan, Michael Chaquin, Claire Hirschauer, Mohamad Mohty, Ollivier Legrand, François Delhommeau, Pierre Hirsch

https://doi.org/10.3324/haematol.2022.280676

Translational readthrough at F8 nonsense variants in factor VIII B domain contributes to residual expression and lowers inhibitor association (46 Online Views)

Maria Francesca Testa, Silvia Lombardi, Francesco Bernardi, Mattia Ferrarese, Donata Belvini, Paolo Radossi, Giancarlo Castaman, Mirko Pinotti, Alessio Branchini

https://doi.org/10.3324/haematol.2022.281279

Letters to the Editor

Onset of blast crisis in chronic myeloid leukemia patients in treatment-free remission (73 Online Views)

Stephanie Dulucq, Sandrine Hayette, Jean-Michel Cayuela, Frédéric Bauduer, Kaddour Chabane, Patrice Chevallier, Pascale Cony-Makhoul, Pascale Flandrin-Gresta, Caroline Le Jeune, Yannick Le Bris, Laurence Legros, Hervé Maisonneuve, Lydia Roy, Francois-Xavier Mahon, Ivan Sloma, Delphine Rea, Franck Emmanuel Nicolini

https://doi.org/10.3324/haematol.2022.280740

Pulmonary function testing for fitness assessment in asymptomatic adults with newly diagnosed acute myeloid leukemia (47 Online Views)

Raffaele Palmieri, Megan Othus, Guang-Shing Cheng, Francesco Buccisano, Giovangiacinto Paterno, Luca Maurillo, Maria Ilaria Del Principe, Giuseppe Sconocchia, Adriano Venditti, Roland B. Walter

https://doi.org/10.3324/haematol.2022.281445

Case Reports

Mass-spectrometry-based proteomics amyloid typing in clinical practice: state-of-the-art from a French nationwide cohort (78 Online Views)

Magali Colombat, Margot Gaspard, Mylène Camus, Jessica Dalloux-Chioccioli, Audrey Delas, Elsa Poullot, Anissa Moktefi, Arnaud François, Anne Moreau, Jean-Bapiste Gibier, Pierre Raynaud, Antoine Huart, Alexis Piedrafita, Julia Gilhodes, Olivier Lairez, Gilles Grateau, Sophie Georgin-Lavialle, Hervé Maisonneuve, Philippe Moreau, Arnaud Jaccard, Franck Bridoux, Violaine Plante-Bordeneuve, Thibaud Damy, Hervé Mal, Pierre Brousset, Sophie Valleix, Odile Burlet-Schiltz

https://doi.org/10.3324/haematol.2022.281431

Jul 28, 2022

Editorials
Article

Improving the anti-acute myeloid leukemia activity of CD123-specific Engager T cells by MyD88 and CD40 costimulation (549 Online Views)

Abishek Vaidya, Erin Doherty, Xiya Wu, Sujuan Huang, Nikhil Hebbar, Unmesha Thanekar, Challice L. Bonifant, Cheng Cheng, Stephen Gottschalk, M. Paulina Velasquez

https://doi.org/10.3324/haematol.2021.279301

Review Articles

Articles

Analysis of rare driving events in pediatric acute myeloid leukemia (212 Online Views)

Sanne Noort, Jolieke van Oosterwijk, Jing Ma, Elizabeth A.R. Garfinkle, Stephanie Nance, Michael Walsh, Guangchun Song, Dirk Reinhardt, Martina Pigazzi, Franco Locatelli, Henrik Hasle, Jonas Abrahamsson, Marie Jarosova, Charikleia Kelaidi, Sophia Polychronopoulou, Marry M. van den Heuvel-Eibrink, Maarten Fornerod, Tanja A. Gruber, C. Michel Zwaan

https://doi.org/10.3324/haematol.2021.280250

Letters to the Editor

Minnesota acute GvHD risk score predicts survival at onset of GvHD after PTCy prophylaxis (105 Online Views)

Federica Ardizzoia, Francesca Lorentino, Alessandro Bruno, Sarah Marktel, Fabio Giglio, Daniela Clerici, Francesca Farina, Sara Mastaglio, Simona Piemontese, Andrea A. Assanelli, Matteo G. Carrabba, Massimo Bernardi, Consuelo Corti, Jacopo Peccatori, Fabio Ciceri, Raffaella Greco, Maria Teresa Lupo-Stanghellini

https://doi.org/10.3324/haematol.2022.281269

Case Reports

Acute myeloid leukemia early after anti-CD19 chimeric antigen receptor T cells infusion in a patient with refractory diffuse large B cell lymphoma and pre-existing clonal hematopoiesis (233 Online Views)

Lorenza Falini, Alessandra Venanzi, Valentina Tini, Alessandra Innocente, Stelvio Ballanti, Simonetta Saldi, Silvio Sivolella, Antonio Pierini, Cynthia Aristei, Enrico Tiacci, Vincenzo Maria Perriello, Brunangelo Falini

https://doi.org/10.3324/haematol.2022.281351

Jul 21, 2022

Editorials
Article

Hypercortisolemic Cushing's patients possess a distinct class of hematopoietic progenitor cells leading to erythrocytosis (244 Online Views)

Lilian Varricchio, Eliza B Geer, Fabrizio Martelli, Maria Mazzarini, Alister Funnell, James J Bieker, Thalia Papayannopoulou, Anna Rita Migliaccio

https://doi.org/10.3324/haematol.2021.280542

Editorials
Article

Time spent at home among older adults with acute myeloid leukemia receiving azacitidine- or venetoclax-based regimens (252 Online Views)

Christopher E. Jensen, Hilary M. Heiling, Konan E. Beke, Allison M. Deal, Ashley L. Bryant, Lorinda A. Coombs, Matthew C. Foster, Daniel R. Richardson

https://doi.org/10.3324/haematol.2022.280728

Letters to the Editor

Guidelines

Thrombosis in multiple myeloma: risk stratification, antithrombotic prophylaxis, and management of acute events. A consensus-based position paper from an ad hoc expert panel (199 Online Views)

Valerio De Stefano, Alessandra Larocca, Monica Carpenedo, Michele Cavo, Francesco Di Raimondo, Anna Falanga, Massimo Offidani, Maria Teresa Petrucci, Marco Ruggeri, Roberto Mario Santi, Giovanni Barosi

https://doi.org/10.3324/haematol.2022.280893

Jul 14, 2022

Editorials

Articles

RHOA regulated IGFBP2 promotes invasion and drives progression of BCR-ABL1 chronic myeloid leukemia (341 Online Views)

Hualei Zhang, Baohuan Cai, Yun Liu, Yating Chong, Atsuko Matsunaga, Stephanie Fay Mori, Xuexiu Fang, Eiko Kitamura, Chang-Sheng Chang, Ping Wang, John K Cowell, Tianxiang Hu

https://doi.org/10.3324/haematol.2022.280757

Allogeneic transplant following CAR T-cell therapy for large B-cell lymphoma (692 Online Views)

Joanna Zurko, Jeremy Ramdial, Mazyar Shadman, Sairah Ahmed, Aniko Szabo, Lorenzo Iovino, Ana Alarcon Tomas, Craig Sauter, Miguel-Angel Perales, Nirav. N. Shah, Utkarsh H. Acharya, Caron Jacobson, Robert J. Soiffer, Trent Wang, Krishna V. Komanduri, Samantha Jaglowski, Adam S. Kittai, Nathan Denlinger, Madiha Iqbal, Mohamed A. Kharfan-Dabaja, Ernesto Ayala, Julio Chavez, Michael Jain, Frederick L. Locke, Yazeed Samara, Lihua E. Budde, Matthew G. Mei, Alexandra Della Pia, Tatyana Feldman, Nausheen Ahmed, Ryan Jacobs, Nilanjan Ghosh, Bhagirathbhai Dholaria, Olalekan O. Oluwole, Brian Hess, Ayesha Hassan, Vaishalee P. Kenkre, Patrick Reagan, Farrukh Awan, Yago Nieto, Mehdi Hamadani, Alex F. Herrera

https://doi.org/10.3324/haematol.2022.281242

Letters to the Editor

Histological, genetic characterization and follow-up of 130 patients with chronic triplenegative thrombocytosis. (367 Online Views)

Sandrine Lemoine, Clelia Mornet, Isabelle Quintin-Roue, Marie-Christine Rousselet, Laurane Cottin, Aurélie Georgeais, Ludovic Dubouis, Françoise Boyer, Corentin Orvain, Clara Caillon, Maxime Renard, Valoris Le Brun, Lenaig Le Clech, Jean-Christophe Ianotto, Emmanuelle Génin, Barbara Burroni, Valérie Ugo, Damien Luque Paz, Eric Lippert

https://doi.org/10.3324/haematol.2022.280917

Extranodal presentation in limited stage diffuse large B-cell lymphoma as a prognostic marker in three SWOG trials S0014, S0313 and S1001 (151 Online Views)

Deborah M. Stephens, Hongli Li, Louis S. Constine, Thomas J. Fitzgerald, John P. Leonard, Brad S. Kahl, Joo Y. Song, Michael L. LeBlanc, Sonali M. Smith, Daniel O. Persky, Jonathan W. Friedberg

https://doi.org/10.3324/haematol.2022.281004

Inflammation in Waldenström macroglobulinemia is associated with 6q deletion and need for treatment initiation (164 Online Views)

Nathalie Forgeard, Marine Baron, Jonathan Caron, Clementine Boccon-Gibod, Daphne Krzisch, Nayara Guedes, Veronique Morel, Nathalie Jacque, Maya Ouzegdouh, Sylvain Choquet, Clotilde Bravetti, Florence Nguyen-Khac, Elise Chapiro, Veronique Leblond, Damien Roos-Weil

https://doi.org/10.3324/haematol.2022.281053

Jul 7, 2022

Articles

Comparative analysis of oral and intravenous iron therapy in rat models of inflammatory anemia and iron deficiency (518 Online Views)

Lara Valente de Souza, Alexander Hoffmann, Christine Fischer, Verena Petzer, Malte Asshoff, Igor Theurl, Piotr Tymoszuk, Markus Seifert, Natascha Brigo, Richard Hilbe, Egon Demetz, Laura Von Raffay, Sylvia Berger, Marina Barros-Pinkelnig, Guenter Weiss

https://doi.org/10.3324/haematol.2022.281149

Letters to the Editor

Association of FLT3-ITD length with overall survival in acute myeloid leukemia: a systematic review and meta-analysis (450 Online Views)

Tobias B. Polak, Joost van Rosmalen, Stijn Dirven, Julia K. Herzig, Jacqueline Cloos, Soheil Meshinchi, Konstanze Döhner, Jeroen J.W.M. Janssen, David G.J. Cucchi

https://doi.org/10.3324/haematol.2022.281218

Platelet functional abnormalities and clinical presentation in pediatric patients with germline RUNX1, ANKRD26, and ETV6 mutations (705 Online Views)

Galina S. Ovsyannikova, Daria V. Fedorova, Ivan P. Tesakov, Alexey A. Martyanov, Anastasia A. Ignatova, Evgeniya A. Ponomarenko, Pavel A. Zharkov, Anna V. Pavlova, Elena V. Raykina, Michael A. Maschan, Mikhail A. Panteleev, Galina A. Novichkova, Anastasia N. Sveshnikova, Nataliya S. Smetanina

https://doi.org/10.3324/haematol.2022.281340

Case Reports

Jun 30, 2022

Editorials
Article

Comparison of autologous and allogeneic hematopoietic cell transplantation strategies in patients with primary plasma cell leukemia, with dynamic prediction modelling (472 Online Views)

Sarah Lawless, Simona Iacobelli, Nina Simone Knelange, Patrice Chevallier, Didier Blaise, Noel Milpied, Roberto Foà, Jan J. Cornelissen, Bruno Lioure, Ruben Benjamin, Xavier Poiré, Monique C. Minnema, Matthew Collin, Stig Lenhoff, John A. Snowden, Stella Santarone, Keith M. O. Wilson, Fernanda Trigo, Peter Dreger, Lara H. Böhmer, Hein Putter, Laurent Garderet, Nicolaus Kröger, Ibrahim Yaukoub-Agha, Stefan Schönland, Curly Morris

https://doi.org/10.3324/haematol.2021.280568

Editorials
Article

Comparison of autologous and allogeneic hematopoietic cell transplantation strategies in patients with primary plasma cell leukemia, with dynamic prediction modelling (472 Online Views)

Sarah Lawless, Simona Iacobelli, Nina Simone Knelange, Patrice Chevallier, Didier Blaise, Noel Milpied, Roberto Foà, Jan J. Cornelissen, Bruno Lioure, Ruben Benjamin, Xavier Poiré, Monique C. Minnema, Matthew Collin, Stig Lenhoff, John A. Snowden, Stella Santarone, Keith M. O. Wilson, Fernanda Trigo, Peter Dreger, Lara H. Böhmer, Hein Putter, Laurent Garderet, Nicolaus Kröger, Ibrahim Yaukoub-Agha, Stefan Schönland, Curly Morris

https://doi.org/10.3324/haematol.2021.280568

Review Articles

IgM monoclonal gammopathies of clinical significance: diagnosis and management (2133 Online Views)

Jahanzaib Khwaja, Shirley D’Sa, Monique C Minnema, Marie José Kersten, Ashutosh Wechalekar, Josephine M Vos

https://doi.org/10.3324/haematol.2022.280953

Articles

Combination elotuzumab and lenalidomide treatment efficacy is dependent on crosstalk between NK cells, monocytes and myeloma cells (348 Online Views)

Kelden Richardson, Simon P. Keam, Joe Jiang Zhu, Deborah Meyran, Criselle D’Souza, Sean Macdonald, Kerry Campbell, Michael Robbins, Natalie A. Bezman, Kirsten Todd, Hang Quach, David S. Ritchie, Simon J. Harrison, H. Miles Prince, Joseph A. Trapani, Misty R. Jenkins, Paul A. Beavis, Phillip K. Darcy, Paul J. Neeson

https://doi.org/10.3324/haematol.2021.279930

Axicabtagene ciloleucel compared to tisagenlecleucel for the treatment of aggressive B-cell lymphoma (1534 Online Views)

Mi Kwon, Gloria Iacoboni, Juan Luis Reguera, Lucía López Corral, Rafael Hernani Morales, Valentín Ortiz-Maldonado, Manuel Guerreiro, Ana Carolina Caballero, María Luisa Guerra Domínguez, Jose Maria Sanchez Pina, Alberto Mussetti, Juan Manuel Sancho, Mariana Bastos-Oreiro, Eva Catala, Javier Delgado, Hugo Luzardo Henriquez, Jaime Sanz, María Calbacho, Rebeca Bailén, Cecilia Carpio, Jose Maria Ribera, Anna Sureda, Javier Briones, Juan Carlos Hernandez-Boluda, Nuria Martínez Cebrián, Jose Luis Diez Martin, Alejandro Martín, Pere Barba

https://doi.org/10.3324/haematol.2022.280805

Clinical features of hepatitis E infections in patients with hematological disorders (217 Online Views)

Susanne Ghandili, Cecilia Lindhauer, Sven Pischke, Julian Schulze zur Wiesch, Philipp H. von Kroge, Susanne Polywka, Carsten Bokemeyer, Walter Fiedler, Nicolaus Kröger, Francis Ayuk, Raissa Adjallé, Franziska Modemann

https://doi.org/10.3324/haematol.2022.280853

Letters to the Editor

Myeloablative fractionated busulfan conditioning regimen with post-transplant cyclophosphamide in HLA matched and haploidentical transplantation: results of a phase II study (162 Online Views)

Uday R. Popat, Borje S Andersson, Roland Bassett, Jitesh Kawedia, Ben C. Valdez, Amin M. Alousi, Gheath Al-Atrash, Qaiser Bashir, Chitra M. Hosing, Jin S. Im, Partow Kebriaei, David Marin, Yago Nieto, Betul Oran, Amanda Olson, Muzaffar H. Qazilbash, Samer A. Srour, Elizabeth J. Shpall, Richard E. Champlin, Rohtesh S. Mehta

https://doi.org/10.3324/haematol.2022.280778

Molecular predictors of response to venetoclax plus hypomethylating agent in treatment-naïve acute myeloid leukemia (450 Online Views)

Naseema Gangat, Isla Johnson, Kristen McCullough, Faiqa Farrukh, Aref Al-Kali, Hassan Alkhateeb, Kebede Begna, Abhishek Mangaonkar, Mark Litzow, William Hogan, Mithun Shah, Mrinal Patnaik, Animesh Pardanani, Ayalew Tefferi

https://doi.org/10.3324/haematol.2022.281214

Jun 23, 2022

Editorials
Article

STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of BCL2 and BCLXL following glucocorticoid treatment (306 Online Views)

Jordy C.G. van der Zwet, Valentina Cordo’, Jessica G.C.A.M. Buijs-Gladdines, Rico Hagelaar, Willem K. Smits, Eric Vroegindeweij, Laura T.M. Graus, Vera Poort, Marloes Nulle, Rob Pieters, Jules P.P. Meijerink

https://doi.org/10.3324/haematol.2021.280405

Articles

Impaired immunosuppressive role of myeloid-derived suppressor cells in acquired aplastic anemia (415 Online Views)

Peiyuan Dong, Lingyun Chen, Hongfei Wu, Jiali Huo, Zhongxing Jiang, Yingqi Shao, Xiang Ren, Jinbo Huang, Xingxin Li, Min Wang, Neng Nie, Jing Zhang, Peng Jin, Yizhou Zheng, Meili Ge

https://doi.org/10.3324/haematol.2021.280292

In-depth characterization of intratumoral heterogeneity in refractory B-cell non-Hodgkin lymphoma through the lens of a Research Autopsy Program (190 Online Views)

Keren Isaev, Ting Liu, Mehran Bakhtiari, Kit Tong, Rashmi Goswami, Bernard Lam, Ilinca Lungu, Paul M. Krzyzanowski, Amit Oza, Neesha Dhani, Anca Prica, Michael Crump, Robert Kridel

https://doi.org/10.3324/haematol.2022.280900

Letters to the Editor

A phase I/II multicenter, open-label, dose escalation and randomized trial of BI 836858 in patients with low or intermediate-1 risk myelodysplastic syndrome (236 Online Views)

Rami S. Komrokji, Hetty E. Carraway, Ulrich Germing, Martin Wermke, Amer M. Zeidan, Eric Fu, Björn Rüter, Ute Burkard, Annika Osswald, James M. Foran

https://doi.org/10.3324/haematol.2021.280500

Primary outcomes by 1q21+ status for isatuximab-treated patients with relapsed/refractory multiple myeloma: Subgroup analyses from ICARIA-MM and IKEMA (1365 Online Views)

Tom Martin, Paul G Richardson, Thierry Facon, Philippe Moreau, Aurore Perrot, Ivan Spicka, Kamlesh Bisht, Marlene Inchauspé, France Casca, Sandrine Macé, Helgi van de Velde, Kenshi Suzuki

https://doi.org/10.3324/haematol.2022.280660

COVID-19 vaccine-induced adverse events predict immunogenicity among recipients of allogeneic haematopoietic stem cell transplantation (163 Online Views)

Hanna Grauers Wiktorin, Sigrun Einarsdottir, Andreas Törnell, Mohammad Arabpour, Nuttida Issdisai, Jesper Waldenström, Johan Ringlander, Magnus Lindh, Martin Lagging, Kristoffer Hellstrand, Anna Martner

https://doi.org/10.3324/haematol.2022.280813

SARS-CoV-2-specific cellular response following third COVID-19 vaccination in patients with chronic lymphocytic leukemia (203 Online Views)

Sibylle C. Mellinghoff, Leonie Mayer, Sandra Robrecht, Leonie M. Weskamm, Christine Dahlke, Henning Gruell, Maike Schlotz, Kanika Vanshylla, Hans A. Schloser, Martin Thelen, Anna-Maria Fink, Kirsten Fischer, Florian Klein, Marylyn M. Addo, Barbara Eichhorst, Michael Hallek, Petra Langerbeins

https://doi.org/10.3324/haematol.2022.280982

Daunorubicin-60 vs daunorubicin-90 vs idarubicin-12 for induction chemotherapy in acute myeloid leukemia: a retrospective analysis of the Mayo Clinic experience (215 Online Views)

Ayalew Tefferi, Naseema Gangat, Mithun Shah, Hassan Alkhateeb, Mrinal S. Patnaik, Aref Al-Kali, Michelle A. Elliott, William J. Hogan, Mark R. Litzow, Christopher C. Hook, Abhishek Mangaonkar, David Viswanatha, Dong Chen, Animesh Pardanani, Rhett P. Ketterling, Kebede H. Begna

https://doi.org/10.3324/haematol.2022.281045

Case Reports

Jun 16, 2022

Editorials
Article

Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning (502 Online Views)

Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina M. Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang E. Berdel, Wolfgang Hiddemann, Frank Kroschinsky, Johannes Schetelig, Uwe Platzbecker, Carsten Müller-Tidow, Tim Sauer, Hubert Serve, Claudia Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan Krause, Mathias Hänel, Christoph Schliemann, Maher Hanoun, Christian Thiede, Martin Bornhäuser, Karsten Wendt, Jan Moritz Middeke

https://doi.org/10.3324/haematol.2021.280027

Review Articles

Articles

Monomorphic epitheliotropic intestinal T-cell lymphoma comprises morphologic and genomic heterogeneity impacting outcome (367 Online Views)

Luis Veloza, Doriane Cavalieri, Edoardo Missiaglia, Albane Ledoux-Pilon, Bettina Bisig, Bruno Pereira, Christophe Bonnet, Elsa Poullot, Leticia Quintanilla-Martinez, Romain Dubois, Francisco Llamas-Gutierrez, Céline Bossard, Roland De Wind, Fanny Drieux, Juliette Fontaine, Marie Parrens, Jeremy Sandrini, Virginie Fataccioli, Marie-Hélène Delfau-Larue, Adrien Daniel, Faustine Lhomme, Lauriane Clément-Filliatre, François Lemonnier, Anne Cairoli, Pierre Morel, Sylvie Glaisner, Bertrand Joly, Abderrazak El Yamani, Kamel Laribi, Emmanuel Bachy, Reiner Siebert, David Vallois, Philippe Gaulard, Olivier Tournilhac, Laurence de Leval

https://doi.org/10.3324/haematol.2022.281226

Jun 9, 2022

Articles

PET-imaging assessment for guiding strategy in patients with relapsed/refractory large B-cell lymphoma receiving CAR T-cells (387 Online Views)

Jean Galtier, Laetitia Vercellino, Loic Chartier, Pierre Olivier, Claire Tabouret-Viaud, Charles Mesguich, Roberta Di Blasi, Amandine Durand, Léo Raffy, François-Xavier Gros, Isabelle Madelaine, Veronique Meignin, Miryam Mebarki, Marie-Thérèse Rubio, Pierre Feugier, Olivier Casasnovas, Michel Meignan, Catherine Thieblemont

https://doi.org/10.3324/haematol.2021.280550

Characteristics and outcome of patients with acute myeloid leukemia and trisomy 4 (284 Online Views)

Sabine Kayser, David Martínez-Cuadrón, Maher Hanoun, Friedrich Stölzel, Cristina Gil, H. Christian Reinhardt, Eliana Aguiar, Kerstin Schäfer-Eckart, Juan Miguel Bergua Burgues, Björn Steffen, Teresa Bernal, Stefan W. Krause, Rosalía Riaza, Christoph Schliemann, Jose Cervera, Martin Kaufmann, Laura Torres-Miñana, Mathias Hänel, Evelyn Acuña-Cruz, Edgar Jost, Jesus Lorenzo Algarra, Martina Crysandt, Lars Fransecky, Javier Cornago-Navascues, Sabrina Kraus, Joaquin Martinez-Lopez, Hermann Einsele, Dirk Niemann, Andreas Neubauer, Ruth Seggewiß-Bernhardt, Sebastian Scholl, Stefan A. Klein, Christoph Schmid, Markus Schaich, Martin Schmidt-Hieber, Sven Zukunft, Anthony D. Ho, Uwe Platzbecker, Claudia D. Baldus, Carsten Müller-Tidow, Christian Thiede, Martin Bornhäuser, Hubert Serve, Mark Levis, Pau Montesinos, Christoph Röllig, Richard F. Schlenk

https://doi.org/10.3324/haematol.2022.281137

Case Reports

May 31, 2022

Editorials
Article

APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis (454 Online Views)

Simon Stritt, Paquita Nurden, Alan T. Nurden, Jean-François Schved, Jean-Claude Bordet, Maguelonne Roux, Marie-Christine Alessi, David-Alexandre Trégouët, Taija Mäkinen, Muriel Giansily-Blaizot

https://doi.org/10.3324/haematol.2022.280816

Articles

High-risk stage IIB Hodgkin lymphoma treated in the H10 and AHL2011 trials: TMTV is a useful risk factor to stratify patients at baseline (376 Online Views)

Cédric Rossi, Marc André, Jehan Dupuis, Franck Morschhauser, Bertrand Joly, Julien Lazarovici, Hervé Ghesquières, Aspasia Stamatoullas, Emmanuelle Nicolas-Virelizier, Pierre Feugier, Anne-Claire Gac, Hannah Moatti, Luc-Matthieu Fornecker, Bénédicte Deau, Clémentine Joubert, Catherine Fortpied, John Raemaekers, Massimo Federico, Salim Kanoun, Michel Meignan, Alexandra Traverse-Glehen, Anne-Ségolène Cottereau, René-Olivier Casasnova

https://doi.org/10.3324/haematol.2021.280004

Letters to the Editor

Inducing synthetic lethality for selective targeting of acute myeloid leukemia cells harboring STAG2 mutations (298 Online Views)

Agatheeswaran Subramaniam, Carl Sandén, Larissa Moura-Castro, Kristijonas Žemaitis, Ludwig Schmiderer, Aurelie Baudet, Alexandra Bäckström, Elin Arvidsson, Simon Hultmark, Natsumi Miharada, Mattias Magnusson, Kajsa Paulsson, Thoas Fioretos, Jonas Larsson

https://doi.org/10.3324/haematol.2021.280303

Cytomegalovirus proteins, maternal pregnancy cytokines, and their impact on neonatal immune cytokine profiles and acute lymphoblastic leukemogenesis in children (186 Online Views)

Joseph L. Wiemels, Rong Wang, Mi Zhou, Helen Hansen, Rachel Gallant, Junghyun Jung, Nicholas Mancuso, Adam J. de Smith, Catherine Metayer, Scott C. Kogan, Xiaomei Ma

https://doi.org/10.3324/haematol.2022.280826

May 26, 2022

Editorials
Article

Durable discontinuation of systemic therapy in patients affected by chronic graft-versus-host disease (1101 Online Views)

George L. Chen, Lynn Onstad, Paul J. Martin, Paul Carpenter, Joseph Pidala, Sally Arai, Corey Cutler, Betty K. Hamilton, Stephanie J. Lee, Mukta Arora

https://doi.org/10.3324/haematol.2021.279814

Editorials
Article

Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease (278 Online Views)

Iryna A. Khasabova, Jacob Gable, Malcolm Johns, Sergey G. Khasabov, Alexander E. Kalyuzhny, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, Virginia S. Seybold, Donald A. Simone

https://doi.org/10.3324/haematol.2021.280460

Articles

Regulation of Human T-cell leukemia virus type 1 antisense promoter by myocyte enhancer factor-2C in the context of adult T-cell leukemia and lymphoma (370 Online Views)

Kiran K. Madugula, Julie Joseph, Catherine DeMarino, Rashida Ginwala, Vanessa Teixeira, Zafar K. Khan, Dominic Sales, Sydney Wilson, Fatah Kashanchi, Amanda W. Rushing, Isabelle Lemasson, Edward W. Harhaj, Murali Janakiram, B. Hilda Ye, Pooja Jain

https://doi.org/10.3324/haematol.2021.279542

Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells (417 Online Views)

Sarah Warsi, Maria Dahl, Emma M. K. Smith, Anna Rydstrom, Els Mansell, Valgardur Sigurdsson, Julia Sjoberg, Shamit Soneji, Emma Rorby, Kavitha Siva, Tan H. M. Grahn, Yang Liu, Ulrika Blank, Goran Karlsson, Stefan Karlsson

https://doi.org/10.3324/haematol.2021.279799

Comparable long-term outcomes between upfront haploidentical and identical sibling donor transplant in aplastic anemia: a national registry-based study (778 Online Views)

Zheng-Li Xu, Lan-Ping Xu, De-Pei Wu, Shun-Qing Wang, Xi Zhang, Rui Xi, Su-Jun Gao, Ling-Hui Xia, Jian-Min Yang, Ming Jiang, Xin Wang, Qi-Fa Liu, Jia Chen, Ming Zhou, Xiao-Jun Huang

https://doi.org/10.3324/haematol.2022.280758

Kinetics of early and late molecular recurrences after first-line imatinib cessation in chronic myeloid leukemia: updated results from the STIM2 trial (275 Online Views)

Stéphanie Dulucq, Franck E. Nicolini, Delphine Rea, Pascale Cony-Makhoul, Aude Charbonnier, Martine Escoffre-Barbe, Valérie Coiteux, Pascal Lenain, Françoise Rigal-Huguet, Jixing Liu, Agnès Guerci-Bresler, Laurence Legros, Jean-Christophe Ianotto, Martine Gardembas, Pascal Turlure, Viviane Dubruille, Philippe Rousselot, Juliana Martiniuc, Henry Jardel, Hyacinthe Johnson-Ansah, Bertrand Joly, Tawfiq Henni, Emilie Cayssials, Patricia Zunic, Marc G. Berger, Bruno Villemagne, Fanny Robbesyn, Stephane Morisset, François-Xavier Mahon, Gabriel Etienne

https://doi.org/10.3324/haematol.2022.280811

Letters to the Editor

Autologous stem cell transplantation in an older adult population (212 Online Views)

Kateryna Fedorov, Tanim Jain, Kith Pradhan, Jennat Mustafa, Amanda Lombardo, Fariha Khatun, Felisha Joseph, Kailyn Gillick, Anjali Naik, Richard Elkind, Karen Fehn, Alyssa de Castro, Roy Browne, Michelly Abreu, Donika Binakaj, Monika Paroder, Carlo Palesi, Kira Gritsman, R Alejandro Sica, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Nishi Shah, Amit Verma, Ira Braunschweig, Mendel Goldfinger

https://doi.org/10.3324/haematol.2022.281020

Case Reports

The successful use of eculizumab for treatment of thrombotic microangiopathy in pediatric acute SARS-CoV2 infection and multisystem inflammatory syndrome in children (284 Online Views)

Tarun Aurora, Noel Joseph, Senthil Velan Bhoopalan, Miguela A. Caniza, Tim Flerlage, Saad Ghafoor, Jane Hankins, Diego R. Hijano, Rohith Jesudas, Justin Kirkham, Hugo Martinez, Gabriela Maron Alfaro, Akshay Sharma, Melissa Hines

https://doi.org/10.3324/haematol.2022.280603

Prolonged remission with pembrolizumab and radiation therapy in a patient with multisystem Langerhans cell sarcoma (264 Online Views)

Saurabh Zanwar, Aishwarya Ravindran, Jithma P. Abeykoon, Jason R. Young, Timothy F. Kozelsky, Karen L. Rech, Gaurav Goyal, Ronald S. Go

https://doi.org/10.3324/haematol.2022.280948

May 19, 2022

Editorials
Article

Impact of PET-CT status on progression-free survival for relapsed follicular lymphoma patients undergoing autologous stem cell transplant (433 Online Views)

Toby A. Eyre, Sally F. Barrington, Jessica Okosun, Clementina Abamba, Rachel M. Pearce, Julia Lee, Ben Carpenter, Charles R. Crawley, Adrian J.C. Bloor, Maria Gilleece, Emma Nicholson, Nimish Shah, Kim Orchard, Ram Malladi, William M. Townsend

https://doi.org/10.3324/haematol.2021.280287

Letters to the Editor

Profound and sustained response with next generation ALK inhibitors in patients with relapsed or progressive ALK-positive anaplastic large cell lymphoma with central nervous system involvement (254 Online Views)

Charlotte Rigaud, Samuel Abbou, Stephane Ducassou, Mathieu Simonin, Lou Le Mouel, Victor Pereira, Stephanie Gourdon, Anne Lambilliotte, Birgit Geoerger, Veronique Minard-Colin, Laurence Brugieres

https://doi.org/10.3324/haematol.2021.280081

ETV6-related thrombocytopenia: dominant negative effect of mutations as common pathogenic mechanism (335 Online Views)

Michela Faleschini, Daniele Ammeti, Nicole Papa, Caterina Alfano, Roberta Bottega, Giorgia Fontana, Valeria Capaci, Melania E. Zanchetta, Federico Pozzani, Francesca Montanari, Valeria Petroni, Paola Giordano, Patrizia Noris, Fiorina Giona, Anna Savoia

https://doi.org/10.3324/haematol.2022.280729

May 12, 2022

Editorials
Letter to the Editor

Integrating biological HLA-DPB1 mismatch models to predict survival after unrelated hematopoietic cell transplantation (317 Online Views)

Annalisa Ruggeri, Liesbeth C. de Wreede, Carlheinz R. Müller, Pietro Crivello, Edouard F. Bonneville, Effie W. Petersdorf, Gerard Socié, Valérie Dubois, Riitta Niittyvuopio, Juha Peräsaari, Ibrahim Yakoub-Agha, Jan J. Cornelissen, Lotte Wieten, Tobias Gedde-Dahl, Edouard Forcade, Charles R. Crawley, Steven G.E. Marsh, Virginie Gandemer, Eleni Tholouli, Claude-Eric Bulabois, Anne Huynh, Goda Choi, Eric Deconinck, Maija Itäla-Remes, Stig Lenhoff, Mats Bengtsson, Jan-Erik Johansson, Gwendolyn van Gorkom, Jorinde D. Hoogenboom, Luca Vago, Vanderson Rocha, Chiara Bonini, Christian Chabannon, Katharina Fleischhauer

https://doi.org/10.3324/haematol.2021.280055

Articles

Assessment of functional shunting in patients with sickle cell disease (258 Online Views)

Liza Afzali-Hashemi, Lena Václavů, John C. Wood, Bart J. Biemond, Aart J. Nederveen, Henk J.M.M. Mutsaerts, Anouk Schrantee

https://doi.org/10.3324/haematol.2021.280183

COVID-19 in adult acute myeloid leukemia patients: a long-term followup study from the European Hematology Association survey (EPICOVIDEHA) (867 Online Views)

Francesco Marchesi, Jon Salmanton-García, Ziad Emarah, Klára Piukovics, Marcio Nucci, Alberto López-García, Zdeněk Ráčil, Francesca Farina, Marina Popova, Sofia Zompi, Ernesta Audisio, Marie-Pierre Ledoux, Luisa Verga, Barbora Weinbergerová, Tomas Szotkovski, Maria Gomes Da Silva, Nicola Fracchiolla, Nick De Jonge, Graham Collins, Monia Marchetti, Gabriele Magliano, Carolina García-Vidal, Monika M. Biernat, Jaap Van Doesum, Marina Machado, Fatih Demirkan, Murtadha Al-Khabori, Pavel Žák, Benjamín Víšek, Igor Stoma, Gustavo-Adolfo Méndez, Johan Maertens, Nina Khanna, Ildefonso Espigado, Giulia Dragonetti, Luana Fianchi, Maria Ilaria Del Principe, Alba Cabirta, Irati Ormazabal-Vélez, Ozren Jaksic, Caterina Buquicchio, Valentina Bonuomo, Josip Batinić, Ali S. Omrani, Sylvain Lamure, Olimpia Finizio, Noemí Fernández, Iker Falces-Romero, Ola Blennow, Rui Bergantim, Natasha Ali, Sein Win, Jens Van Praet, Maria Chiara Tisi, Ayten Shirinova, Martin Schönlein, Juergen Prattes, Monica Piedimonte, Verena Petzer, Milan Navrátil, Austin Kulasekararaj, Pavel Jindra, Jiří Sramek, Andreas Glenthøj, Rita Fazzi, Cristina De Ramón-Sánchez, Chiara Cattaneo, Maria Calbacho, Nathan C. Bahr, Shaimaa El-Ashwah, Raul Cordoba, Michaela Hanakova, Giovanni Zambrotta, Mariarita Sciumè, Stephen Booth, Raquel Nunes Rodrigues, Maria Vittoria Sacchi, Nicole García-Poutón, Juan-Alberto Martín-González, Sofya Khostelidi, Stefanie Gräfe, Laman Rahimli, Emanuele Ammatuna, Alessandro Busca, Paolo Corradini, Martin Hoenigl, Nikolai Klimko, Philipp Koehler, Antonio Pagliuca, Francesco Passamonti, Oliver A. Cornely, Livio Pagano

https://doi.org/10.3324/haematol.2022.280847

Letters to the Editor

The gut microbiome in patients with chronic lymphocytic leukemia (361 Online Views)

Tereza Faitová, Rebecka Svanberg, Caspar da Cunha-Bang, Emma E. Ilett, Mette Jørgensen, Marc Noguera-Julian, Roger Paredes, Cameron R. MacPherson, Carsten U. Niemann

https://doi.org/10.3324/haematol.2021.280455

A validated clinical-genetic score for assessing the risk of thrombosis in patients with COVID-19 receiving thromboprophylaxis (343 Online Views)

José Manuel Soria, Sergi Mojal, Angel Martinez-Perez, Francisco René Acosta, Sonia López, Sara Miqueleiz, Diana Rodriguez, Maria Angeles Quijada, Antonio Cardenas, Francisco Vidal, Angel Remacha, Rosa Maria Antonijoan, Juan Carlos Souto

https://doi.org/10.3324/haematol.2022.281068

May 5, 2022

Articles

Patient- and physician-reported pain after tyrosine kinase inhibitor discontinuation among patients with chronic myeloid leukemia (590 Online Views)

Kathryn E Flynn, Ehab Atallah, Li Lin, Neil P Shah, Richard T Silver, Richard A. Larson, Javier Panilla-Ibarz, James E. Thompson, Vivian G. Oehler, Jerald P. Radich, Vamsi Kota, Michael J Mauro, Charles A Schiffer, Jorge Cortes, Kevin P Weinfurt

https://doi.org/10.3324/haematol.2021.280377

Relapse of immune-mediated thrombotic thrombocytopenic purpura following mRNA COVID-19 vaccination: a prospective cohort study (701 Online Views)

Gaetano Giuffrida, Uros Markovic, Annalisa Condorelli, Marianna Calagna, Stephanie Grasso, Andrea Duminuco, Carla Riccobene, Angelo Curto Pelle, Guido Zanghi, Francesco Di Raimondo

https://doi.org/10.3324/haematol.2022.280702

Letters to the Editor

Deregulated JAK3 mediates growth advantage and hemophagocytosis in extranodal nasal-type natural killer/T cell lymphoma (372 Online Views)

Adrien Picod, Suella Martino, Pascale Cervera, Gregory Manuceau, Marc Arca, Monica Wittner, YanYan Zhang, He Liang, Florian Beghi, Eric Solary, Fawzia Louache, Paul Coppo

https://doi.org/10.3324/haematol.2021.280349

Pure erythroid leukemia is characterized by biallelic TP53 inactivation and abnormal p53 expression patterns in de novo and secondary cases (438 Online Views)

Hong Fang, Sa A. Wang, Joseph D. Khoury, Siba El Hussein, Do Hwan Kim, Mehrnoosh Tashakori, Zhenya Tang, Shaoying Li, Zhihong Hu, Fatima Zahra Jelloul, Keyur P. Patel, Timothy J. McDonnell, Tapan Kadia, L. Jeffrey Medeiros, Wei Wang

https://doi.org/10.3324/haematol.2021.280487

Beta adrenergic signaling regulates HSPC commitment and therapy sensitivity in multiple myeloma (476 Online Views)

Remya Nair, Vimal Subramaniam, Benjamin G. Barwick, Vikas A. Gupta, Shannon M. Matulis, Sagar Lonial, Lawrence H. Boise, Ajay K. Nooka, Kuzhali Muthumalaiappan, Mala Shanmugam

https://doi.org/10.3324/haematol.2022.280907

Apr 28, 2022

Editorials
Article

Focal structural variants revealed by whole genome sequencing disrupt the histone demethylase KDM4C in B cell lymphomas (538 Online Views)

Cristina Lopez, Nikolai Schleussner, Stephan H. Bernhart, Kortine Kleinheinz, Stephanie Sungalee, Henrike L. Sczakiel, Helene Kretzmer, Umut H. Toprak, Selina Glaser, Rabea Wagener, Ole Ammerpohl, Susanne Bens, Maciej Giefing, Juan C. Gonzalez Sanchez, Gordana Apic, Daniel Hubschmann, Martin Janz, Markus Kreuz, Anja Mottok, Judith M. Muller, Julian Seufert, Steve Hoffmann, Jan O. Korbel, Robert B. Russell, Roland Schule, Lorenz Trumper, Wolfram Klapper, Bernhard Radlwimmer, Peter Lichter, Ralf Kuppers, Matthias Schlesner, Stephan Mathas, Reiner Siebert

https://doi.org/10.3324/haematol.2021.280005

Editorials

Editorials

Editorials
Article

Molecular characterisation and clinical outcome of B-cell precursor acute lymphoblastic leukaemia with IG-MYC rearrangement (668 Online Views)

Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. de Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell

https://doi.org/10.3324/haematol.2021.280557

Articles

Resistance to PI3κδ inhibitors in marginal zone lymphoma can be reverted by targeting the IL-6/PDGFRA axis (920 Online Views)

Alberto J. Arribas, Sara Napoli, Luciano Cascione, Giulio Sartori, Laura Barnabei, Eugenio Gaudio, Chiara Tarantelli, Afua Adjeiwaa Mensah, Filippo Spriano, Antonella Zucchetto, Francesca M Rossi, Andrea Rinaldi, Manuel Castro de Moura, Sandra Jovic, Roberta Bordone-Pittau, Alessandra Di Veroli, Anastasios Stathis, Gabriele Cruciani, Georg Stussi, Valter Gattei, Jennifer R Brown, Manel Esteller, Emanuele Zucca, Davide Rossi, Francesco Bertoni

https://doi.org/10.3324/haematol.2021.279957

Total late effect burden in long-term lymphoma survivors after high-dose therapy with autologous stem-cell transplant and its effect on health-related quality of life (809 Online Views)

Knut Smeland, Harald Holte, Unn-Merete Fagerli, Hanne Bersvendsen, Marianne J. Hjermstad, Jon H. Loge, Klaus Murbrach, Marianne D. Linnsund, Oystein Fluge, Jo S. Stenehjem, May B. Lund, Stein Kvaloy, Cecilie E. Kiserud

https://doi.org/10.3324/haematol.2021.280413

Phenotypic and functional characterization of the CD6-ALCAM T cell costimulatory pathway after allogeneic cell transplantation (571 Online Views)

Benedetta Rambaldi, Haesook T. Kim, Yohei Arihara, Takeru Asano, Carol Reynolds, Mariah Manter, Max Halpern, Augustine Weber, John Koreth, Corey Cutler, Mahasweta Gooptu, Sarah Nikiforow, Vincent T. Ho, Joseph H. Antin, Rizwan Romee, Jeanette Ampudia, Cherie Ng, Stephen Connelly, Robert J. Soiffer, Jerome Ritz

https://doi.org/10.3324/haematol.2021.280444

Erdheim-Chester disease: look it in the eye. An orbital MRI study (239 Online Views)

Julien Haroche, Yoram Gueniche, Damien Galanaud, Fleur Cohen-Aubart, Didier Dormont, Théophile Rousseau, Zahir Amoura, Valerie Touitou, Natalia Shor

https://doi.org/10.3324/haematol.2021.280510

Apr 21, 2022

Editorials
Article

The mutational landscape in chronic myelomonocytic leukemia and its impact on allogeneic hematopoietic cell transplantation outcomes: a Center for Blood and Marrow Transplantation Research (CIBMTR) analysis (1294 Online Views)

Matthew Mei, Raju Pillai, Soyoung Kim, Noel Estrada-Merly, Michelle Afkhami, Lixin Yang, Zhuo Meng, Muhammad Bilal Abid, Mahmoud Aljurf, Ulrike Bacher, Amer Beitinjaneh, Christopher Bredeson, Jean-Yves Cahn, Jan Cerny, Edward Copelan, Corey Cutler, Zachariah DeFilipp, Miguel Angel Diaz Perez, Nosha Farhadfar, César O. Freytes, Shahinaz M. Gadalla, Siddhartha Ganguly, Robert Peter Gale, Usama Gergis, Michael R. Grunwald, Betty K. Hamilton, Shahrukh Hashmi, Gerhard C. Hildebrandt, Hillard M. Lazarus, Mark Litzow, Reinhold Munker, Hemant S. Murthy, Sunita Nathan, Taiga Nishihori, Sagar S. Patel, David Rizzieri, Sachiko Seo, Mithun Vinod Shah, Melhem Solh, Leo F. Verdonck, Ravi Vij, Ronald M. Sobecks, Betul Oran, Bart L. Scott, Wael Saber, Ryotaro Nakamura

https://doi.org/10.3324/haematol.2021.280203

Editorials
Letter to the Editor

Crosstalk between β-catenin and WT1 signalling activity in acute myeloid leukemia (549 Online Views)

Megan Wagstaff, Olga Tsaponina, Gilian Caalim, Hayley Greenfield, Leanne Milton-Harris, Erika J Mancini, Allison Blair, Kate J Heesom, Alex Tonks, Richard L Darley, Stefan G Roberts, Rhys G Morgan

https://doi.org/10.3324/haematol.2021.280294

Articles

Evidence of protective effects of recombinant ADAMTS13* in humanized model for sickle cell disease (392 Online Views)

Paolo Rossato, Enrica Federti, Alessandro Matte, Helmut Glantschnig, Fabio Canneva, Maria Schuster, Sogue Coulibaly, Gerald Schrenk, Dirk Voelkel, Michael Dockal, Barbara Plaimauer, Immacolata Andolfo, Achille Iolascon, Hanspeter Rottensteiner, Herbert Gritsch, Friedrich Scheiflinger, Werner Hoellriegl, Lucia De Franceschi

https://doi.org/10.3324/haematol.2021.280233

Case Reports

Apr 14, 2022

Editorials

Articles

Genomic determinants impacting the clinical outcome of mogamulizumab treatment for adult T-cell leukemia/lymphoma (498 Online Views)

Norio Tanaka, Seiichi Mori, Kazuma Kiyotani, Yuki Ota, Osamu Gotoh, Shigeru Kusumoto, Nobuaki Nakano, Youko Suehiro, Asahi Ito, Ilseung Choi, Eiichi Ohtsuka, Michihiro Hidaka, Kisato Nosaka, Makoto Yoshimitsu, Yoshitaka Imaizumi, Shinsuke Iida, Atae Utsunomiya, Tetsuo Noda, Hiroyoshi Nishikawa, Ryuzo Ueda, Takashi Ishida

https://doi.org/10.3324/haematol.2021.280352

Apr 7, 2022

Articles

Treatment-free remission in chronic myeloid leukemia patients treated front-line with nilotinib: 10-year follow-up of the GIMEMA CML 0307 study (612 Online Views)

Gabriele Gugliotta, Fausto Castagnetti, Massimo Breccia, Luciano Levato, Tamara Intermesoli, Mariella D'Adda, Marzia Salvucci, Fabio Stagno, Giovanna Rege-Cambrin, Mario Tiribelli, Bruno Martino, Monica Bocchia, Michele Cedrone, Elena Trabacchi, Francesco Cavazzini, Ferdinando Porretto, Federica Sorà, Maria Pina Simula, Francesco Albano, Simona Soverini, Robin Foà, Fabrizio Pane, Michele Cavo, Giuseppe Saglio, Michele Baccarani, Gianantonio Rosti

https://doi.org/10.3324/haematol.2021.280175

Iron- and erythropoietin-resistant anemia in a spontaneous breast cancer mouse model (500 Online Views)

Nuria Fabregas Bregolat, Maja Ruetten, Milene Costa da Silva, Mostafa A. Aboouf, Hyrije Ademi, Nadine von Büren, Julia Armbruster, Martina Stirn, Sandro Altamura, Oriana Marques, Josep M. Monné Rodriguez, Victor J. Samillan, Rashim Pal Singh, Ben Wielockx, Martina U. Muckenthaler, Max Gassmann, Markus Thiersch

https://doi.org/10.3324/haematol.2022.280732

The deglycosylated form of 1E12 inhibits platelet activation and prothrombotic effects induced by VITT antibodies (489 Online Views)

Caroline Vayne, Raghavendra Palankar, Sandra Billy, Stefan Handtke, Thomas Thiele, Charlotte Cordonnier, Claire Pouplard, Andreas Greinacher, Yves Gruel, Jérôme Rollin

https://doi.org/10.3324/haematol.2021.280251

Mar 31, 2022

Articles

Final analysis of the phase 3 non-inferiority COLUMBA study of subcutaneous versus intravenous daratumumab in patients with relapsed or refractory multiple myeloma (1091 Online Views)

Saad Z. Usmani, Hareth Nahi, Wojciech Legiec, Sebastian Grosicki, Vladimir Vorobyev, Ivan Spicka, Vania Hungria, Sibirina Korenkova, Nizar J. Bahlis, Max Flogegard, Joan Bladé, Philippe Moreau, Martin Kaiser, Shinsuke Iida, Jacob Laubach, Hila Magen, Michele Cavo, Cyrille Hulin, Darrell White, Valerio De Stefano, Kristen Lantz, Lisa O’Rourke, Christoph Heuck, Maria Delioukina, Xiang Qin, Ivo Nnane, Ming Qi, Maria-Victoria Mateos

https://doi.org/10.3324/haematol.2021.279459

Glycolytic enzyme PFKFB3 determines bone marrow endothelial progenitor cell damage post chemotherapy and irradiation (652 Online Views)

Zhong-Shi Lyu, Shu-Qian Tang, Tong Xing, Yang Zhou, Meng Lv, Hai-Xia Fu, Yu Wang, Lan-Ping Xu, Xiao-Hui Zhang, Hsiang-Ying Lee, Yuan Kong, Xiao-Jun Huang

https://doi.org/10.3324/haematol.2021.279756

Acute central nervous system toxicity during treatment of pediatric acute lymphoblastic leukemia: phenotypes, risk factors and genotypes (662 Online Views)

Stavroula Anastasopoulou, Rikke Linnemann Nielsen, Bodil Als-Nielsen, Joanna Banerjee, Mats A. Eriksson, Marianne Helenius, Mats M. Heyman, Inga Maria Johannsdottir, Olafur Gisli Jonsson, Stuart MacGregor, Marion K. Mateos, Chelsea Mayoh, Sirje Mikkel, Ida Hed Myrberg, Riitta Niinimäki, Kjeld Schmiegelow, Mervi Taskinen, Goda Vaitkeviciene, Anna Warnqvist, Benjamin Wolthers, Arja Harila-Saari, Susanna Ranta

https://doi.org/10.3324/haematol.2021.280016

Preclinical evaluation and structural optimization of anti-BCMA CAR to target multiple myeloma (825 Online Views)

Ortal Harush, Nathalie Asherie, Shlomit Kfir-Erenfeld, Galit Adler, Tilda Barliya, Miri Assayag, Moshe E. Gatt, Polina Stepensky, Cyrille J. Cohen

https://doi.org/10.3324/haematol.2021.280169

Fc galactosylation of anti-platelet hIgG1 alloantibodies enhance complement activation on platelets (566 Online Views)

Thijs L.J. van Osch, Janita J. Oosterhoff, Arthur E. H. Bentlage, Jan Nouta, Carolien A. M. Koeleman, Dionne M. Geerdes, Juk Yee Mok, Sebastiaan Heidt, Arend Mulder, Wim J. E. van Esch, Rick Kapur, Leendert Porcelijn, C. Ellen van der Schoot, Masja de Haas, Manfred Wuhrer, Jan Voorberg, Gestur Vidarsson

https://doi.org/10.3324/haematol.2021.280493

Mar 24, 2022

Editorials
Article

Autologous stem cell transplantation as consolidation of first-line chemotherapy in patients with peripheral T-cell lymphoma: a multicenter GELTAMO/FIL study (965 Online Views)

Alejandro Martín García-Sancho, Monica Bellei, Miriam López-Parra, Giuseppe Gritti, María Cortés, Silvana Novelli, Carlos Panizo, Luigi Petrucci, Antonio Gutiérrez, Ivan Dlouhy, Mariana Bastos-Oreiro, Juan M. Sancho, María J. Ramírez, José M. Moraleda, Estrella Carrillo, Ana I. Jiménez-Ubieto, Isidro Jarque, Lorella Orsucci, Estefanía García-Torres, Carlos Montalbán, Anna Dodero, Reyes Arranz, Natalia de las Heras, María J. Pascual, Javier López-Jiménez, Michelle Spina, Alessandro Re, Sonia González de Villambrosia, Sabela Bobillo, Massimo Federico, Dolores Caballero

https://doi.org/10.3324/haematol.2021.279426

Mar 17, 2022

Editorials
Article

Clinical relevance of an objective – limit of detection – limit of quantification - based flow cytometry approach for measurable residual disease assessment in acute myeloid leukemia. A post-hoc analysis of the GIMEMA AML1310 trial. (497 Online Views)

Francesco Buccisano, Raffaele Palmieri, Alfonso Piciocchi, Valentina Arena, Luca Maurillo, Maria-Ilaria Del Principe, Giovangiacinto Paterno, Maria-Antonietta Irno-Consalvo, Tiziana Ottone, Mariadomenica Divona, Consuelo Conti, Daniela Fraboni, Serena Lavorgna, William Arcese, Maria Teresa Voso, Adriano Venditti

https://doi.org/10.3324/haematol.2021.279777

Editorials

Articles

Specific inhibition of the transporter MRP4/ABCC4 affects multiple signaling pathways and thrombus formation in human platelets (435 Online Views)

Robert Wolf, Sophie Grammbauer, Raghavendra Palankar, Céline Tolksdorf, Eileen Moritz, Andreas Böhm, Mahmoud Hasan, Annika Hafkemeyer, Andreas Greinacher, Mladen V. Tzvetkov, Bernhard H. Rauch, Gabriele Jedlitschky

https://doi.org/10.3324/haematol.2021.279761

Syndromes predisposing to leukemia are a major cause of inherited cytopenias in children (774 Online Views)

Oded Gilad, Orly Dgany, Sharon Noy-Lotan, Tanya Krasnov, Joanne Yacobovich, Ron Rabinowicz, Tracie Goldberg, Amir A. Kuperman, Abed Abu-Quider, Hagit Miskin, Noa Kapelushnik, Noa Mandel-Shorer, Shai Shimony, Dan Harlev, Tal Ben-Ami, Etai Adam, Carina Levin, Shraga Aviner, Ronit Elhasid, Sivan Berger-Achituv, Lilach Chaitman-Yerushalmi, Yona Kodman, Nino Oniashvilli, Michal Hameiri-Grosman, Shai Izraeli, Hannah Tamary, Orna Steinberg-Shemer

https://doi.org/10.3324/haematol.2021.280116

Mar 10, 2022

Editorials
Article

The IL32/BAFF axis supports prosurvival dialogs in the lymphoma ecosystem and is disrupted by NIK inhibition (575 Online Views)

Salomé Decombis, Antonin Papin, Céline Bellanger, Clara Sortais, Christelle Dousset, Yannick Le Bris, Thiphanie Riveron, Stéphanie Blandin, Philippe Hulin, Benoit Tessoulin, Mathieu Rouel, Steven Le Gouill, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck, David Chiron

https://doi.org/10.3324/haematol.2021.279800

Articles

Extracellular vesicles mediate the communication between multiple myeloma and bone marrow microenvironment in a NOTCH dependent way (711 Online Views)

Domenica Giannandrea, Natalia Platonova, Michela Colombo, Mara Mazzola, Valentina Citro, Raffaella Adami, Filippo Maltoni, Silvia Ancona, Vincenza Dolo, Ilaria Giusti, Andrea Basile, Anna Pistocchi, Laura Cantone, Valentina Bollati, Lavinia Casati, Elisabetta Calzavara, Mauro Turrini, Elena Lesma, Raffaella Chiaramonte

https://doi.org/10.3324/haematol.2021.279716

High tumor burden before blinatumomab has a negative impact on the outcome of adult patients with B-cell precursor acute lymphoblastic leukemia. A real-world study by the GRAALL (679 Online Views)

Aurelie Cabannes-Hamy, Eolia Brissot, Thibaut Leguay, Francoise Huguet, Patrice Chevallier, Mathilde Hunault, Martine Escoffre-Barbe, Thomas Cluzeau, Marie Balsat, Stephanie Nguyen, Florence Pasquier, Magda Alexis, Veronique Lheritier, Cedric Pastoret, Eric Delabesse, Emmanuelle Clappier, Herve Dombret, Nicolas Boissel

https://doi.org/10.3324/haematol.2021.280078

Mar 3, 2022

Articles

Rituximab in addition to LMB-based chemotherapy regimen in children and adolescents with primary mediastinal large B-cell lymphoma: results of the French LMB2001 prospective study. (697 Online Views)

Marie Emilie Dourthe, Aurélie Phulpin, Anne Auperin, Jacques Bosq, Marie-Laure Couec, Peggy Dartigues, Stéphane Ducassou, Nathalie Garnier, Stéphanie Haouy, Thierry Leblanc, Amaury Leruste, Catherine Paillard, Charlotte Rigaud, Mathieu Simonin, Catherine Patte, Véronique Minard-Colin

https://doi.org/10.3324/haematol.2021.280257

Feb 24, 2022

Editorials
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Pseudo-mutant P53 is a unique phenotype of DNMT3A-mutated pre-leukemia (887 Online Views)

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