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Novel ligand-binding domain truncated CPSF7::RARA::CPSF7 tripartite fusion confers primary ATRA resistance in atypical acute promyelocytic leukemia

Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Precision Medicine Research Center, Beijing Lu Daopei Institute of Hematology, Beijing
Precision Medicine Research Center, Beijing Lu Daopei Institute of Hematology, Beijing, China; Department of Pathology and Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001
Key Laboratory of Molecular Diagnosis and Treatment of Hematological Diseases of Shanxi Province，Institute of Hematology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, 030001, China; Shanxi University of Chinese Medicine, No. 121, University Street, Yuci District, Jinzhong City, Shanxi Province
Haematologica Early view Apr 9, 2026 https://doi.org/10.3324/haematol.2026.300631

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Early view : Letters to the Editor
 
DOI
https://doi.org/10.3324/haematol.2026.300631
 
Published
2026-04-09
Published By
Ferrata Storti Foundation, Pavia, Italy
Print ISSN
0390-6078
Online ISSN
1592-8721
 
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