CURRENT ISSUE
May, 2024
No. 109 (5)

Landmark papers in Hematology

Editorials

Review Articles

Articles

Acute Lymphoblastic Leukemia

Profiling the activity of the para-caspase MALT1 in B-cell acute lymphoblastic leukemia for potential targeted therapeutic application (1310 Online Views)

Firas M. Safa, Terri Rasmussen, Lorena Fontan, Min Xia, Ari Melnick, Adrian Wiestner, Patricia Lobelle-Rich, Jan A. Burger, Yara Mouawad, Hana Safah, Erik K. Flemington, Nakhle S. Saba

https://doi.org/10.3324/haematol.2023.283178

Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma (1034 Online Views)

Stien De Coninck, Renate De Smedt, Beatrice Lintermans, Lindy Reunes, Hansen J. Kosasih, Alexandra Reekmans, Lauren M. Brown, Nadine Van Roy, Bruno Palhais, Juliette Roels, Malaika Van der Linden, Jo Van Dorpe, Panagiotis Ntziachristos, Frederik W. van Delft, Marc R. Mansour, Tim Pieters, Tim Lammens, Barbara De Moerloose, Charles E. de Bock, Steven Goossens, Pieter Van Vlierberghe

https://doi.org/10.3324/haematol.2023.283981

Impact of inotuzumab ozogamicin on outcome in relapsed or refractory acute B-cell lymphoblastic leukemia patients prior to allogeneic hematopoietic stem cell transplantation and risk of sinusoidal obstruction syndrome/venous occlusive disease (1343 Online Views)

Sabine Kayser, Chiara Sartor, Fabio Giglio, Alessandro Bruno, Jonathan Webster, Patrizia Chiusolo, Francesco Saraceni, Selene Guerzoni, Lara Pochintesta, Erika Borlenghi, Giovanni Marconi, Irene Zacheo, Marco Cerrano, Prassede Salutari, Francesco Restuccia, Mariachiara Abbenante, Mark J. Levis, Richard F. Schlenk, Cristina Papayannidis

https://doi.org/10.3324/haematol.2023.284310

Hematopoiesis

Differential transcriptional control of hematopoiesis in congenital and cyclic neutropenia patients harboring ELANE mutations (1068 Online Views)

Alexander Zeidler, Natalia Borbaran-Bravo, Benjamin Dannenmann, Malte Ritter, Masoud Nasri, Maksim Klimiankou, Sergey Kandabarau, Azadeh Zahabi, Josef König, Cornelia Zeidler, Julia Skokowa, Karl Welte

https://doi.org/10.3324/haematol.2023.284033

Hodgkin Lymphoma

Overall survival and causes of death in elderly patients with Hodgkin lymphoma: a Norwegian population-based case-control study (711 Online Views)

Kjersti Lia, Rasmus R.K. Jørgensen, Bente L.Wold, Øystein Fluge, Unn-Merete Fagerli, Hanne Bersvendsen, Idun B. Bø, Sameer Bhargava, Alexander Fosså

https://doi.org/10.3324/haematol.2023.283721

Iron Metabolism & its Disorders

Myelodysplastic Syndromes

ASXL1 mutations are associated with a response to alvocidib and 5-azacytidine combination in myelodysplastic neoplasms (1166 Online Views)

Vladimir Riabov, Qingyu Xu, Nanni Schmitt, Alexander Streuer, Guo Ge, Lyndsey Bolanos, Mark Wunderlich, Johann-Christoph Jann, Alina Wein, Eva Altrock, Marie Demmerle, Sanjay Mukherjee, Abdullah Mahmood Ali, Felicitas Rapp, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Ahmed Jawhar, Ali Darwich, Patrick Wuchter, Christel Weiss, Azra Raza, Jason M. Foulks, Daniel T. Starczynowski, Feng-Chun Yang, Georgia Metzgeroth, Laurenz Steiner, Mohamad Jawhar, Wolf-Karsten Hofmann, Daniel Nowak

https://doi.org/10.3324/haematol.2023.282921

Non-Hodgkin Lymphoma

Outcomes of limited stage primary bone diffuse large B-cell lymphoma in the rituximab era: a multicenter, retrospective study (902 Online Views)

Alexandra Rezazadeh, Aniko Szabo, Arushi Khurana, David J. Inwards, Matthew A. Lunning, Nancy L. Bartlett, Paolo F. Caimi, Thomas D. Rodgers, Paul M. Barr, Sayan Mullick Chowdhury, Narendranath Epperla, Hiruni Mendries, Brian T. Hill, Timothy S. Oh, Reem Karmali, Julie E. Chang, Gaurav Goyal, Benjamin M. Parsons, Krista M. Isaac, Craig A. Portell, Kathleen Monahan, Malika Siker, David M. King, Timothy S. Fenske

https://doi.org/10.3324/haematol.2023.283210

SH2 domain-containing inositol 5-phosphatases support the survival of Burkitt lymphoma cells by promoting energy metabolism (902 Online Views)

Florian Mayr, Vanessa Kruse, Dominik C. Fuhrmann, Sebastian Wolf, Jens Löber, Saed Alsouri, Nadia Paglilla, Kwang Lee, Björn Chapuy, Bernhard Brüne, Thorsten Zenz, Björn Häupl, Thomas Oellerich, Michael Engelke

https://doi.org/10.3324/haematol.2023.283663

Effect of delayed cell infusion in patients with large B-cell lymphoma treated with chimeric antigen receptor T-cell therapy (1809 Online Views)

Andrew P. Jallouk, Naishu Kui, Ryan Sun, Jason R. Westin, Raphael E. Steiner, Ranjit Nair, Loretta J. Nastoupil, Luis E. Fayad, Ajlan Al Zaki, Misha Hawkins, Sherry Adkins, Mansoor Noorani, Kaberi Das, Jared Henderson, Elizabeth J. Shpall, Partow Kebriaei, Jeremy Ramdial, Christopher R. Flowers, Sattva S. Neelapu, Sairah Ahmed, Paolo Strati

https://doi.org/10.3324/haematol.2023.284453

Plasma Cell Disorders

Autologous-allogeneic versus autologous tandem stem cell transplantation and maintenance therapy with thalidomide for multiple myeloma patients under 60 years of age: a prospective, phase II study (1576 Online Views)

Nicolaus Kröger, Gerald Wulf, Ute Hegenbart, Andreas Burchert, Matthias Stelljes, Nico Gagelmann, Arne Brecht, Martin Kaufmann, Lutz Müller, Arnold Ganser, Dominik Wolf, Wolfgang Bethge, Martin Bornhäuser, Michael Kiehl, Eva-Maria Wagner, Christoph Schmid, Hans Christian Reinhardt, Guido Kobbe, Hans Salwender, Thomas Heinicke, Martin Kropff, Marion Heinzelmann, Francis Ayuk, Lorenz Trümper, Andreas Neubauer, Andreas Völp, Evgeny Kluychnikov, Stefan Schönland, Christine Wolschke

https://doi.org/10.3324/haematol.2023.282920

Impact of race and ethnicity on early mortality in multiple myeloma: a SEER analysis (974 Online Views)

John X. Wei, Aditi Shastri, R. Alejandro Sica, Ioannis Mantzaris, Noah Kornblum, Urvi Shah, Murali Janakiram, Kira Gritsman, Amit Verma, Mendel Goldfinger, Dennis Cooper, Nishi Shah

https://doi.org/10.3324/haematol.2023.283304

Pharmacologic targeting of the p62 ZZ domain enhances both anti-tumor and bone-anabolic effects of bortezomib in multiple myeloma (985 Online Views)

Silvia Marino, Daniela N. Petrusca, Ryan T. Bishop, Judith L. Anderson, Hayley M. Sabol, Cody Ashby, Justin H. Layer, Annamaria Cesarano, Utpal P. Davé, Fabiana Perna, Jesus Delgado-Calle, John M. Chirgwin, G. David Roodman

https://doi.org/10.3324/haematol.2023.283787

Factors associated with refractoriness or early progression after idecabtagene vicleucel in patients with relapsed/ refractory multiple myeloma: US Myeloma Immunotherapy Consortium real world experience (1814 Online Views)

Hamza Hashmi, Doris K. Hansen, Lauren C. Peres, Omar Castaneda Puglianini, Ciara Freeman, Gabriel De Avila, Surbhi Sidana, Leyla Shune, Douglas W. Sborov, James Davis, Charlotte Wagner, Mehmet H. Kocoglu, Shebli Atrash, Peter Voorhees, Gary Simmons, Christopher Ferreri, Nilesh Kalariya, Larry D. Anderson Jr., Aimaz Afrough, Danai Dima, Jack Khouri, Joseph McGuirk, Fred Locke, Rachid Baz, Krina K. Patel, Melissa Alsina

https://doi.org/10.3324/haematol.2023.283888

A prospective, multicenter study on hematopoietic stemcell mobilization with cyclophosphamide plus granulocyte colony-stimulating factor and ‘on-demand’ plerixafor in multiple myeloma patients treated with novel agents (854 Online Views)

Roberto Mina, Maria Teresa Petrucci, Francesca Bonello, Velia Bongarzoni, Riccardo Saccardi, Giuseppe Bertuglia, Andrea Mengarelli, Andrea Spadaro, Chiara Lisi, Paola Curci, Roberto Massimo Lemoli, Stelvio Ballanti, Rita Floris, Luca Cupelli, Patrizia Tosi, Attilio Olivieri, Delia Rota-Scalabrini, Clotilde Cangialosi, Chiara Nozzoli, Barbara Anaclerico, Francesca Fazio, Benedetto Bruno, Katia Mancuso, Paolo Corradini, Giuseppe Milone, Mario Boccadoro

https://doi.org/10.3324/haematol.2023.284023

Red Cell Biology & its Disorders

Impaired hemoglobin clearance by sinusoidal endothelium promotes vaso-occlusion and liver injury in sickle cell disease (1075 Online Views)

Tomasz W. Kaminski, Omika Katoch, Ziming Li, Corrine B. Hanway, Rikesh K. Dubey, Adekunle Alagbe, Tomasz Brzoska, Hong Zhang, Prithu Sundd, Gregory J. Kato, Enrico M. Novelli, Tirthadipa Pradhan-Sundd

https://doi.org/10.3324/haematol.2023.283792

Letters to the Editor

The role of the mineralocorticoid receptor in steroidinduced cytotoxicity in pediatric acute lymphoblastic leukemia (535 Online Views)

Annelienke M. van Hulst, Jordy C.G. van der Zwet, Jessica G.C.A.M. Buijs-Gladdines, Willem K. Smits, Marta Fiocco, Rob Pieters, Frank N. van Leeuwen, Marry M. van den Heuvel-Eibrink, Erica L.T. van den Akker, Jules P.P. Meijerink

https://doi.org/10.3324/haematol.2023.282928

Amphiregulin as a biomarker for monitoring lifethreatening acute graft-versus-host disease: secondary analysis of two prospective clinical trials (686 Online Views)

Shernan G. Holtan, Najla El Jurdi, Armin Rashidi, Brian C. Betts, Connor Demorest, John P Galvin, Margaret L. MacMillan, Daniel J. Weisdorf, Angela Panoskaltsis-Mortari, Michael A. Pratta

https://doi.org/10.3324/haematol.2023.283215

A study of 28 pregnant women with sickle cell disease and COVID-19: elevated maternal and fetal morbidity rates (510 Online Views)

Laure Joseph, Gonzalo De Luna, Emmanuelle Bernit, Pierre Cougoul, Aline Santin, Benoit Faucher, Anoosha Habibi, Alain Garou, Gylna Loko, Sarah Mattioni, Sandra Manceau, Jean Benoit Arlet, François Lionnet

https://doi.org/10.3324/haematol.2023.283300

MicroRNA and long non-coding RNA analysis in IgM-monoclonal gammopathies reveals epigenetic influence on cellular functions and oncogenesis (482 Online Views)

Karan Chohan, Jonas Paludo, Surendra Dasari, Patrizia Mondello, Joseph P Novak, Jithma P. Abeykoon, Kerstin Wenzl, Zhi-Zhang Yang, Shahrzad Jalali, Jordan E Krull, Esteban Braggio, Michelle K. Manske, Aneel Paulus, Craig B. Reeder, Sikander Ailawadhi, Asher Chanan-Khan, Prashant Kapoor, Robert A. Kyle, Morie A Gertz, Anne J. Novak, Stephen M. Ansell

https://doi.org/10.3324/haematol.2023.283927

Acute myeloid leukemia-driven IL-3-dependent upregulation of BCL2 in non-malignant hematopoietic stem and progenitor cells increases venetoclax-induced cytopenias (813 Online Views)

Dominic J. Fowler-Shorten, Rebecca S. Maynard, Katherine Hampton, Annalisa Altera, Matthew Markham, Martha Ehikioya, Edyta E. Wojtowicz, Kristian M. Bowles, Stuart A. Rushworth, Charlotte Hellmich

https://doi.org/10.3324/haematol.2023.283944

Deciphering the molecular complexity of the IKZF1plus genomic profile using Optical Genome Mapping (954 Online Views)

Jonathan L. Lühmann, Martin Zimmermann, Winfried Hofmann, Anke K. Bergmann, Anja Möricke, Gunnar Cario, Martin Schrappe, Brigitte Schlegelberger, Martin Stanulla, Doris Steinemann

https://doi.org/10.3324/haematol.2023.284115

Home time among older adults with acute myeloid leukemia by therapy intensity (567 Online Views)

Christopher E. Jensen, Allison M. Deal, Alexis C. Wardell, Hillary M. Heiling, Konan E. Beke, Daniel R. Richardson

https://doi.org/10.3324/haematol.2023.284133

Limited utility of Mayo 2012 cardiac staging system for risk stratification of patients with advanced cardiac AL amyloidosis - analysis of a uniformly treated cohort of 1,275 patients (620 Online Views)

Jahanzaib Khwaja, Sriram Ravichandran, Joshua Bomsztyk, Oliver Cohen, Darren Foard, Ana Martinez-Naharro, Lucia Venneri, Marianna Fontana, Philip N. Hawkins, Julian Gillmore, Helen J. Lachmann, Shameem Mahmood, Carol Whelan, Amy A. Kirkwood, Ashutosh Wechalekar

https://doi.org/10.3324/haematol.2023.284348

Efficacy of combined low-dose ruxolitinib and cyclosporine in murine immune bone marrow failure (551 Online Views)

Xingmin Feng, Ash Lee Manley, Zhijie Wu, Haoran Li, Shouguo Gao, Jibran Durrani, Nidhi Aggarwal, Hiroki Mizumaki, Jichun Chen, Neal S. Young, Emma M. Groarke

https://doi.org/10.3324/haematol.2023.284358

Autologous hematopoietic cell transplantation for T-cell prolymphocytic leukemia: a retrospective study on behalf of the Chronic Malignancies Working Party of the EBMT (556 Online Views)

Joanna Drozd-Sokolowska, Luuk Gras, Linda Koster, Rodrigo Martino, María Queralt Salas, Urpu Salmenniemi, Teresa Zudaire, Lucrecia Yañez, Mar Bellido, Matthew Collin, Martin Kaufmann, Piotr Kozlowski, Xavier Poiré, Christelle Ferra, Antònia Sampol, Keith M. O. Wilson, Anne Cairoli, Tobias Gedde-Dahl, Eric Deconinck, Milena Mirabile, Felipe Suarez, Kavita Raj, Michel van Gelder, Ibrahim Yakoub-Agha, Olivier Tournilhac, Donal P. McLornan

https://doi.org/10.3324/haematol.2023.284359

Rituximab plus cyclophosphamide and dexamethasone versus bortezomib plus cyclophosphamide and dexamethasone in newly diagnosed symptomatic Waldenström macroglobulinemia: a randomized controlled trial (1814 Online Views)

Wenjie Xiong, Rui Lyu, Ying Yu, Tingyu Wang, Yuting Yan, Yi Wang, Wei Liu, Gang An, Shuhui Deng, Yan Xu, Weiwei Sui, Wenyang Huang, Dehui Zou, Jianxiang Wang, Lugui Qiu, Shuhua Yi

https://doi.org/10.3324/haematol.2023.284588

MAF translocation remains a strong prognostic factor despite concurrent chromosomal abnormalities (1341 Online Views)

Yuntong Liu, Rui Lv, Wenqiang Yan, Jingyu Xu, Huishou Fan, Lingna Li, Jian Cui, Chenxing Du, Shuhui Deng, Weiwei Sui, Dehui Zou, Yan Xu, Lugui Qiu, Gang An

https://doi.org/10.3324/haematol.2023.284666

Case Reports

B-cell acute lymphoblastic leukemia and juvenile xanthogranuloma in a patient with ETV6 thrombocytopenia and leukemia predisposition syndrome: novel clinical presentation and perspective (566 Online Views)

Haley Newman, Suzanne P. MacFarland, Garrett M. Brodeur, Timothy Olson, Deepa Bhojwani, Jamie Stokke, Alexandra E. Kovach, Mary Egan Clark, Minjie Luo, Marilyn Li, Amish Shah, Stephen P. Hunger

https://doi.org/10.3324/haematol.2023.284151