April, 2015
No. 100 (4)

Editorials

Review Articles

Articles

Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress (288 Online Views)

Senthil Raja Jayapal, Chelsia Qiuxia Wang, Xavier Bisteau, Matias J. Caldez, Shuhui Lim, Vinay Tergaonkar, Motomi Osato, Philipp Kaldis

https://doi.org/10.3324/haematol.2014.106468

Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology (376 Online Views)

Yuichi Ishikawa, Manami Maeda, Mithun Pasham, Francois Aguet, Silvia K. Tacheva-Grigorova, Takeshi Masuda, Hai Yi, Sung-Uk Lee, Jian Xu, Julie Teruya-Feldstein, Maria Ericsson, Ann Mullally, John Heuser, Tom Kirchhausen, Takahiro Maeda

https://doi.org/10.3324/haematol.2014.119537

A genetic score for the prediction of beta-thalassemia severity (555 Online Views)

Fabrice Danjou, Marcella Francavilla, Franco Anni, Stefania Satta, Franca-Rosa Demartis, Lucia Perseu, Matteo Manca, Maria Carla Sollaino, Laura Manunza, Elisabetta Mereu, Giuseppe Marceddu, Serge Pissard, Philippe Joly, Isabelle Thuret, Raffaella Origa, Joseph Borg, Gian Luca Forni, Antonio Piga, Maria Eliana Lai, Catherine Badens, Paolo Moi, Renzo Galanello

https://doi.org/10.3324/haematol.2014.113886

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form (368 Online Views)

Alessia Pagani, Maud Vieillevoye, Antonella Nai, Marco Rausa, Meriem Ladli, Catherine Lacombe, Patrick Mayeux, Frédérique Verdier, Clara Camaschella, Laura Silvestri

https://doi.org/10.3324/haematol.2014.118521

Elevated hypercoagulability markers in hemoglobin SC disease (179 Online Views)

Marina P. Colella, Erich V. de Paula, João A. Machado-Neto, Nicola Conran, Joyce M. Annichino-Bizzacchi, Fernando F. Costa, Sara T. Olalla Saad, Fabiola Traina

https://doi.org/10.3324/haematol.2014.114587

Multicentric study underlining the interest of adding CD5, CD7 and CD56 expression assessment to the flow cytometric Ogata score in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms (218 Online Views)

Valérie Bardet, Orianne Wagner-Ballon, Julien Guy, Céline Morvan, Camille Debord, Franck Trimoreau, Emmanuel Benayoun, Nicolas Chapuis, Nicolas Freynet, Cédric Rossi, Stéphanie Mathis, Marie-Pierre Gourin, Andréa Toma, Marie C. Béné, Jean Feuillard, Estelle Guérin

https://doi.org/10.3324/haematol.2014.112755

Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I (952 Online Views)

Srdan Verstovsek, Ruben A. Mesa, Jason Gotlib, Richard S. Levy, Vikas Gupta, John F. DiPersio, John V. Catalano, Michael W.N. Deininger, Carole B. Miller, Richard T. Silver, Moshe Talpaz, Elliott F. Winton, Jimmie H. Harvey, Murat O. Arcasoy, Elizabeth O. Hexner, Roger M. Lyons, Azra Raza, Kris Vaddi, William Sun, Wei Peng, Victor Sandor, Hagop Kantarjian

https://doi.org/10.3324/haematol.2014.115840

Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKCα subversion induces up-regulation of PKCβII expression in B lymphocytes (136 Online Views)

Rinako Nakagawa, Milica Vukovic, Anuradha Tarafdar, Emilio Cosimo, Karen Dunn, Alison M. McCaig, Ailsa Holroyd, Fabienne McClanahan, Alan G. Ramsay, John G. Gribben, Alison M. Michie

https://doi.org/10.3324/haematol.2014.112276

Ofatumumab in poor-prognosis chronic lymphocytic leukemia: a Phase IV, non-interventional, observational study from the European Research Initiative on Chronic Lymphocytic Leukemia (523 Online Views)

Carol Moreno, Marco Montillo, Panayiotis Panayiotidis, Maria Dimou, Adrian Bloor, Jehan Dupuis, Anna Schuh, Stefan Norin, Christian Geisler, Peter Hillmen, Michael Doubek, Marek Trněný, Petra Obrtlikova, Luca Laurenti, Stephan Stilgenbauer, Lukas Smolej, Paolo Ghia, Florence Cymbalista, Ulrich Jaeger, Kostas Stamatopoulos, Niki Stavroyianni, Patrick Carrington, Hamadi Zouabi, Veronique Leblond, Juan C. Gomez-Garcia, Martin Rubio, Roberto Marasca, Gerardo Musuraca, Luigi Rigacci, Lucia Farina, Rossella Paolini, Sarka Pospisilova, Eva Kimby, Colm Bradley, Emili Montserrat

https://doi.org/10.3324/haematol.2014.118158

The genotype of MLH1 identifies a subgroup of follicular lymphoma patients who do not benefit from doxorubicin: FIL-FOLL study (227 Online Views)

Davide Rossi, Alessio Bruscaggin, Piera La Cava, Sara Galimberti, Elena Ciabatti, Stefano Luminari, Luigi Rigacci, Alessandra Tucci, Alessandro Pulsoni, Giovanni Bertoldero, Daniele Vallisa, Chiara Rusconi, Michele Spina, Luca Arcaini, Francesco Angrilli, Caterina Stelitano, Francesco Merli, Gianluca Gaidano, Massimo Federico, Giuseppe A. Palumbo

https://doi.org/10.3324/haematol.2014.108183

Trends in incidence, treatment and survival of aggressive B-cell lymphoma in the Netherlands 1989–2010 (171 Online Views)

Djamila E. Issa, Saskia A.M. van de Schans, Martine E.D. Chamuleau, Henrike E. Karim-Kos, Marielle Wondergem, Peter C. Huijgens, Jan Willem W. Coebergh, Sonja Zweegman, Otto Visser

https://doi.org/10.3324/haematol.2014.107300

Successful change of treatment strategy in elderly patients with primary central nervous system lymphoma by de-escalating induction and introducing temozolomide maintenance: results from a phase II study by The Nordic Lymphoma Group (465 Online Views)

Elisa J. Pulczynski, Outi Kuittinen, Martin Erlanson, Hans Hagberg, Alexander Fosså, Mikael Eriksson, Marie Nordstrøm, Bjørn Østenstad, Øystein Fluge, Sirpa Leppä, Bente Fiirgaard, Hanne Bersvendsen, Unn-Merete Fagerli

https://doi.org/10.3324/haematol.2014.108472

Activity of everolimus (RAD001) in relapsed and/or refractory multiple myeloma: a phase I study (227 Online Views)

Andreas Günther, Philipp Baumann, Renate Burger, Christian Kellner, Wolfram Klapper, Ralf Schmidmaier, Martin Gramatzki

https://doi.org/10.3324/haematol.2014.116269

HLA-G expression levels influence the tolerogenic activity of human DC-10 (263 Online Views)

Giada Amodio, Michela Comi, Daniela Tomasoni, Monica Emma Gianolini, Roberta Rizzo, Joël LeMaoult, Maria-Grazia Roncarolo, Silvia Gregori

https://doi.org/10.3324/haematol.2014.113803

T-cell-replete haploidentical transplantation versus autologous stem cell transplantation in adult acute leukemia: a matched pair analysis (194 Online Views)

Norbert-Claude Gorin, Myriam Labopin, Simona Piemontese, William Arcese, Stella Santarone, He Huang, Giovanna Meloni, Felicetto Ferrara, Dietrich Beelen, Miguel Sanz, Andrea Bacigalupo, Fabio Ciceri, Audrey Mailhol, Arnon Nagler, Mohamad Mohty

https://doi.org/10.3324/haematol.2014.111450

Online Only Articles

Clinical and functional implications of microRNA mutations in a cohort of 935 patients with myelodysplastic syndromes and acute myeloid leukemia (230 Online Views)

Felicitas Thol, Michaela Scherr, Aylin Kirchner, Rabia Shahswar, Karin Battmer, Sofia Kade, Anuhar Chaturvedi, Christian Koenecke, Michael Stadler, Uwe Platzbecker, Christian Thiede, Thomas Schroeder, Guido Kobbe, Gesine Bug, Oliver Ottmann, Wolf-Karsten Hofmann, Nicolaus Kröger, Walter Fiedler, Richard Schlenk, Konstanze Döhner, Hartmut Döhner, Jürgen Krauter, Matthias Eder, Arnold Ganser, Michael Heuser

https://doi.org/10.3324/haematol.2014.120345

Refractory anemia with ring sideroblasts and marked thrombocytosis cases harbor mutations in SF3B1 or other spliceosome genes accompanied by JAK2V617F and ASXL1 mutations (286 Online Views)

Sabine Jeromin, Torsten Haferlach, Sandra Weissmann, Manja Meggendorfer, Christiane Eder, Niroshan Nadarajah, Tamara Alpermann, Alexander Kohlmann, Wolfgang Kern, Claudia Haferlach, Susanne Schnittger

https://doi.org/10.3324/haematol.2014.119032

Vincristine, dexamethasone and epratuzumab for older relapsed/refractory CD22+ B-acute lymphoblastic leukemia patients: a phase II study (173 Online Views)

Patrice Chevallier, Francoise Huguet, Emmanuel Raffoux, Anne Etienne, Thibaut Leguay, Francoise Isnard, Nelly Robillard, Thierry Guillaume, Jacques Delaunay, Aude Charbonnier, Arnaud Pigneux, Pierre Peterlin, Marie C. Bené, William A. Wegener, David M. Goldenberg, Hervé Dombret

https://doi.org/10.3324/haematol.2014.120220

Towards personalized therapy in pediatric acute lymphoblastic leukemia: RAS mutations and prednisolone resistance (134 Online Views)

Ingrid M. Ariës, Rosanna E. van den Dungen, Marco J. Koudijs, Edwin Cuppen, Emile Voest, Jan J. Molenaar, Huib N. Caron, Rob Pieters, Monique L. den Boer

https://doi.org/10.3324/haematol.2014.112995

Hydrocortisone does not influence glucocorticoid sensitivity of acute lymphoblastic leukemia cells (183 Online Views)

Lidewij T. Warris, Marry M. van den Heuvel-Eibrink, Ingrid M. Ariës, Rob Pieters, Erica L.T. van den Akker, Monique L. den Boer

https://doi.org/10.3324/haematol.2014.112177

Ibrutinib impairs the phagocytosis of rituximab-coated leukemic cells from chronic lymphocytic leukemia patients by human macrophages (229 Online Views)

Mercedes Borge, María Belén Almejún, Enrique Podaza, Ana Colado, Horacio Fernández Grecco, María Cabrejo, Raimundo F. Bezares, Mirta Giordano, Romina Gamberale

https://doi.org/10.3324/haematol.2014.119669

Evidence for idiotype-directed immunosurveillance is restricted to follicular lymphoma and attributable to somatic hypermutation (154 Online Views)

Dimitrios Papaioannou, Anna-Maria Strothmeyer, Marcus Dühren-von Minden, Andrea Keppler-Hafkemeyer, Katja Zirlik, Kristina Mikesch, Cornelis A.M. van Bergen, Marcelo A. Navarrete, Hendrik Veelken

https://doi.org/10.3324/haematol.2014.111252

The optimized anti-CD20 monoclonal antibody ublituximab bypasses natural killer phenotypic features in Waldenström macroglobulinemia (118 Online Views)

Magali Le Garff-Tavernier, Linda Herbi, Christophe de Romeuf, Nabih Azar, Damien Roos-Weil, Patrick Bonnemye, Rémi Urbain, Véronique Leblond, Hélène Merle-Beral, Vincent Vieillard

https://doi.org/10.3324/haematol.2014.118083

Identification of IG-clonality status as a pre-treatment predictor for mortality in patients with immunodeficiency-associated Epstein-Barr virus-related lymphoproliferative disorders (107 Online Views)

Walter J.F.M. van der Velden, Loes Nissen, Marieke van Rijn, Jos Rijntjes, Anton de Haan, Lakshmi Venkatraman, Mark Catherwood, Hongxiang Liu, Hesham El-Daly, Lisette van de Laar, Moniek H.C.Craenmehr, J. Han J.M. van Krieken, Wendy B.C. Stevens, Patricia J.T.A. Groenen

https://doi.org/10.3324/haematol.2014.116780

Contiguous follicular lymphoma and follicular lymphoma in situ harboring N-glycosylated sites (193 Online Views)

Emilie Mamessier, Charlotte Drevet, Florence Broussais-Guillaumot, Marie-Laure Mollichella, Sylvain Garciaz, Sandrine Roulland, Maxime Benchetrit, Bertrand Nadel, Luc Xerri

https://doi.org/10.3324/haematol.2014.115782