March, 2015
No. 100 (3)

Editorials

Articles

Episodic angioedema with eosinophilia (Gleich syndrome) is a multilineage cell cycling disorder (631 Online Views)

Paneez Khoury, Jacqueline Herold, Alexandra Alpaugh, Ellen Dinerman, Nicole Holland-Thomas, Jennifer Stoddard, Shakuntala Gurprasad, Irina Maric, Olga Simakova, Lawrence B. Schwartz, Juelia Fong, Chyi-Chia Richard Lee, Liqiang Xi, Zengfeng Wang, Mark Raffeld, Amy D. Klion

https://doi.org/10.3324/haematol.2013.091264

Coagulation and its Disorders

Excess of heme induces tissue factor-dependent activation of coagulation in mice (530 Online Views)

Erica M. Sparkenbaugh, Pichika Chantrathammachart, Shaobin Wang, Will Jonas, Daniel Kirchhofer, David Gailani, Andras Gruber, Raj Kasthuri, Nigel S. Key, Nigel Mackman, Rafal Pawlinski

https://doi.org/10.3324/haematol.2014.114728

Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood (1286 Online Views)

Anna M. Aalbers, Marry M. van den Heuvel-Eibrink, Irith Baumann, Michael Dworzak, Henrik Hasle, Franco Locatelli, Barbara De Moerloose, Markus Schmugge, Ester Mejstrikova, Michaela Nováková, Marco Zecca, C. Michel Zwaan, Jeroen G. te Marvelde, Anton W. Langerak, Jacques J.M. van Dongen, Rob Pieters, Charlotte M. Niemeyer, Vincent H.J. van der Velden

https://doi.org/10.3324/haematol.2014.107706

ASXL1 mutations in younger adult patients with acute myeloid leukemia: a study by the German-Austrian Acute Myeloid Leukemia Study Group (583 Online Views)

Peter Paschka, Richard F. Schlenk, Verena I. Gaidzik, Julia K. Herzig, Teresa Aulitzky, Lars Bullinger, Daniela Späth, Veronika Teleanu, Andrea Kündgen, Claus-Henning Köhne, Peter Brossart, Gerhard Held, Heinz-A. Horst, Mark Ringhoffer, Katharina Götze, David Nachbaur, Thomas Kindler, Michael Heuser, Felicitas Thol, Arnold Ganser, Hartmut Döhner, Konstanze Döhner

https://doi.org/10.3324/haematol.2014.114157

Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia (1749 Online Views)

Na Yuan, Lin Song, Suping Zhang, Weiwei Lin, Yan Cao, Fei Xu, Yixuan Fang, Zhen Wang, Han Zhang, Xin Li, Zhijian Wang, Jinyang Cai, Jian Wang, Yi Zhang, Xinliang Mao, Wenli Zhao, Shaoyan Hu, Suning Chen, Jianrong Wang

https://doi.org/10.3324/haematol.2014.113324

A phase II study of vorinostat and rituximab for treatment of newly diagnosed and relapsed/refractory indolent non-Hodgkin lymphoma (306 Online Views)

Robert Chen, Paul Frankel, Leslie Popplewell, Tanya Siddiqi, Nora Ruel, Arnold Rotter, Sandra H. Thomas, Michelle Mott, Nitya Nathwani, Myo Htut, Auayporn Nademanee, Stephen J. Forman, Mark Kirschbaum

https://doi.org/10.3324/haematol.2014.117473

Revisiting the immune microenvironment of diffuse large B-cell lymphoma using a tissue microarray and immunohistochemistry: robust semi-automated analysis reveals CD3 and FoxP3 as potential predictors of response to R-CHOP (327 Online Views)

Rita Coutinho, Andrew J. Clear, Emanuele Mazzola, Andrew Owen, Paul Greaves, Andrew Wilson, Janet Matthews, Abigail Lee, Rute Alvarez, Maria Gomes da Silva, José Cabeçadas, Donna Neuberg, Maria Calaminici, John G. Gribben

https://doi.org/10.3324/haematol.2014.110189

Targeted next-generation sequencing in chronic lymphocytic leukemia: a high-throughput yet tailored approach will facilitate implementation in a clinical setting (591 Online Views)

Lesley-Ann Sutton, Viktor Ljungström, Larry Mansouri, Emma Young, Diego Cortese, Veronika Navrkalova, Jitka Malcikova, Alice F. Muggen, Martin Trbusek, Panagiotis Panagiotidis, Frederic Davi, Chrysoula Belessi, Anton W. Langerak, Paolo Ghia, Sarka Pospisilova, Kostas Stamatopoulos, Richard Rosenquist

https://doi.org/10.3324/haematol.2014.109777

GRP78-directed immunotherapy in relapsed or refractory multiple myeloma - results from a phase 1 trial with the monoclonal immunoglobulin M antibody PAT-SM6 (581 Online Views)

Leo Rasche, Johannes Duell, Inês C. Castro, Valentina Dubljevic, Manik Chatterjee, Stefan Knop, Frank Hensel, Andreas Rosenwald, Hermann Einsele, Max S. Topp, Stephanie Brändlein

https://doi.org/10.3324/haematol.2014.117945

Lenalidomide and dexamethasone for acute light chain-induced renal failure: a phase II study (359 Online Views)

Heinz Ludwig, Elisabeth Rauch, Thomas Kuehr, Zdeněk Adam, Adalbert Weißmann, Hedwig Kasparu, Eva-Maria Autzinger, Daniel Heintel, Richard Greil, Wolfram Poenisch, Ercan Müldür, Niklas Zojer

https://doi.org/10.3324/haematol.2014.115204

Tyrosine kinase inhibitors improve long-term outcome of allogeneic hematopoietic stem cell transplantation for adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia (553 Online Views)

Eolia Brissot, Myriam Labopin, Marielle M. Beckers, Gérard Socié, Alessandro Rambaldi, Liisa Volin, Jürgen Finke, Stig Lenhoff, Nicolaus Kröger, Gert J. Ossenkoppele, Charles F. Craddock, Ibrahim Yakoub-Agha, Günhan Gürman, Nigel H. Russell, Mahmoud Aljurf, Michael N. Potter, Armon Nagler, Oliver Ottmann, Jan J. Cornelissen, Jordi Esteve, Mohamad Mohty

https://doi.org/10.3324/haematol.2014.116954

Letters to the Editor

Online Only Articles

Hedgehog pathway mutations in T-cell acute lymphoblastic leukemia (217 Online Views)

Antonis Dagklis, Daphnie Pauwels, Idoya Lahortiga, Ellen Geerdens, Emilie Bittoun, Barbara Cauwelier, Thomas Tousseyn, Anne Uyttebroeck, Johan Maertens, Gregor Verhoef, Peter Vandenberghe, Jan Cools

https://doi.org/10.3324/haematol.2014.119248

The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells (291 Online Views)

Niels Weinhold, Tobias Meissner, David C Johnson, Anja Seckinger, Jérôme Moreaux, Asta Försti, Bowang Chen, Jolanta Nickel, Daniel Chubb, Andrew C. Rawstron, Chi Doughty, Nasrin B. Dahir, Dil B. Begum, Kwee Young, Brian A. Walker, Per Hoffmann, Marcus M. Nöthen, Faith E. Davies, Bernard Klein, Hartmut Goldschmidt, Gareth J. Morgan, Richard S Houlston, Dirk Hose, Kari Hemminki

https://doi.org/10.3324/haematol.2014.118786

Comments

The closely related rare and severe acute myeloid leukemias carrying EVI1 or PRDM16 rearrangements share singular biological features (102 Online Views)

Marion Eveillard, Jacques Delaunay, Steven Richebourg, Laurence Lodé, Richard Garand, Soraya Wuillème, François Duhoux, Hélène Antoine-Poirel, Catherine Godon, Marie C. Béné

https://doi.org/10.3324/haematol.2014.121079

Rapid elevation of transferrin saturation and serum hepcidin concentration in hemodialysis patients after intravenous iron infusion (228 Online Views)

Natalia Kitsati, Dimitrios Liakos, Eleni Ermeidi, Michalis D. Mantzaris, Spyros Vasakos, Eleni Kyratzopoulou, Petros Eliadis, Emilios Andrikos, Elisavet Kokkolou, Georgios Sferopoulos, Avgi Mamalaki, Konstantinos Siamopoulos, Dimitrios Galaris

https://doi.org/10.3324/haematol.2014.116806

Bleeding before prophylaxis in severe hemophilia: paradigm shift over two decades (147 Online Views)

Annelies Nijdam, Carmen Altisent, Manuel D. Carcao, Ana R. Cid, Ségolène Claeyssens-Donadel, Karin Kurnik, Rolf Ljung, Beatrice Nolan, Pia Petrini, Helen Platokouki, Anne Rafowicz, Angela E. Thomas, Kathelijn Fischer

https://doi.org/10.3324/haematol.2014.115709

A novel CD46 mutation in a patient with microangiopathy clinically resembling thrombotic thrombocytopenic purpura and normal ADAMTS13 activity (236 Online Views)

Raffaella Rossio, Luca Andrea Lotta, Silvia Pontiggia, Nicolò Ghiringhelli Borsa, Isabella Garagiola, Gianluigi Ardissino, Danijela Mikovic, Massimo Cugno, Flora Peyvandi

https://doi.org/10.3324/haematol.2014.111062

Multi-center randomized open label phase II trial on three rituximab dosing schemes in immune thrombocytopenia patients (450 Online Views)

Jaap J. Zwaginga, Bronno van der Holt, Peter A. te Boekhorst, Bart J. Biemond, Mark-David Levin, René van der Griend, Anneke Brand, Sonja Zweegman, Hans F.M. Pruijt, Vera M.J. Novotny, Art Vreugdenhil, Marco R. de Groot, Okke de Weerdt, Elisabeth C.M. van Pampus, Tanja M. van Maanen-Lamme, Shulamiet Wittebol, Martin R. Schipperus, Matthijs H. Silbermann, Peter C. Huijgens, Marleen Luten, Rene Hollestein, Jan A.C. Brakenhoff, Jolanda G. Schrama, Fransje A.A. Valster, Gerjo A. Velders, Harry R. Koene

https://doi.org/10.3324/haematol.2014.110213

Myelodysplastic syndromes with a deletion 5q display a characteristic immunophenotypic profile suitable for diagnostics and response monitoring (159 Online Views)

Uta Oelschlaegel, Theresia M. Westers, Brigitte Mohr, Michael Kramer, Stefani Parmentier, Katja Sockel, Christian Thiede, Martin Bornhäuser, Gerhard Ehninger, Arjan A. van de Loosdrecht, Uwe Platzbecker

https://doi.org/10.3324/haematol.2014.115725

Minimal residual disease monitored after induction therapy by RQ-PCR can contribute to tailor treatment of patients with t(8;21) RUNX1-RUNX1T1 rearrangement (259 Online Views)

Martina Pigazzi, Elena Manara, Barbara Buldini, Valzerda Beqiri, Valeria Bisio, Claudia Tregnago, Roberto Rondelli, Riccardo Masetti, Maria Caterina Putti, Franca Fagioli, Carmelo Rizzari, Andrea Pession, Franco Locatelli, Giuseppe Basso

https://doi.org/10.3324/haematol.2014.114579