December, 2023
No. 108 (12)

Landmark papers in Hematology

Editorials

Review Series

Peripheral T-Cell Lymphomas

Articles

Acute Lymphoblastic Leukemia

Effect of two additional doses of intrathecal methotrexate during induction therapy on serious infectious toxicity in pediatric patients with acute lymphoblastic leukemia (1189 Online Views)

Janina Heilmann, Simon Vieth, Anja Möricke, Andishe Attarbaschi, Draga Barbaric, Nicole Bodmer, Antonella Colombini, Luciano Dalla-Pozza, Sarah Elitzur, Shai Izraeli, Georg Mann, Felix Niggli, Daniela Silvestri, Jan Stary, Carmelo Rizzari, Maria Grazia Valsecchi, Ester Zapotocka, Martin Zimmermann, Gunnar Cario, Martin Schrappe, Valentino Conter

https://doi.org/10.3324/haematol.2022.281788

Impact of central nervous system involvement in adult patients with Philadelphia-negative acute lymphoblastic leukemia: a GRAALL-2005 study (1224 Online Views)

Corentin Orvain, Sylvain Chantepie, Xavier Thomas, Martine Escofrre-Barbe, Francoise Huguet, Yohan Desbrosses, Gaelle Guillerm, Madalina Uzunov, Thibaut Leguay, Sarah Barbieux, Norbert Vey, Patrice Chevallier, Jean-Valere Malfuson, Stephane Lepretre, Michael Baumann, Murat Aykut, Abdelaziz Chaib, Magalie Joris, Hacene Zerazhi, Georg Stussi, Jacques Chapiro, Celine Berthon, Caroline Bonmati, Eric Jourdan, Diana Carp, Amb roise Marcais, Maria-Pilar Gallego-Hernanz, Iona Vaida, Karin Bilger, Alban Villate, Florence Pasquier, Yves Chalandon, Sebastien Maury, Veronique Lheritier, Norbert Ifrah, Herve Dombret, Nicolas Boissel, Mathilde Hunault-Berger.

https://doi.org/10.3324/haematol.2022.282332

Bone Marrow Failure

Conditional survival and standardized mortality ratios of patients with severe aplastic anemia surviving at least one year after hematopoietic cell transplantation or immunosuppressive therapy (1878 Online Views)

Ryotaro Nakamura, Bhavisha A. Patel, Soyoung Kim, F. Lennie Wong, Saro H. Armenian, Emma M. Groarke, Daniel A. Keesler, Kyle M. Hebert, Michael Heim, Mary Eapen, Neal S. Young

https://doi.org/10.3324/haematol.2023.282781

Hematopoiesis

Clonal hematopoiesis with DNMT3A and PPM1D mutations impairs regeneration in autologous stem cell transplant recipients (2278 Online Views)

Patrick Stelmach, Sarah Richter, Sandra Sauer, Margarete A. Fabre, Muxin Gu, Christian Rohde, Maike Janssen, Nora Liebers, Rumyana Proynova, Niels Weinhold, Marc S. Raab, Hartmut Goldschmidt, Birgit Besenbeck, Petra Pavel, Sascha Laier, Andreas Trumpp, Sascha Dietrich, George S. Vassiliou, Carsten Müller-Tidow

https://doi.org/10.3324/haematol.2023.282992

Myeloproliferative Disorders

Haploidentical donor hematopoietic cell transplantation for myelodysplastic/myeloproliferative overlap neoplasms: results from a North American collaboration (1705 Online Views)

Tania Jain, Hua-Ling Tsai, Hany Elmariah, Pankit Vachhani, Theodoros Karantanos, Sarah A Wall, Lukasz P. Gondek, Asad Bashey, Alla Keyzner, Roni Tamari, Michael R. Grunwald, Sameem Abedin, Kalyan VG Nadiminti, Madiha Iqbal, Aaron T Gerds, Auro Viswabandya, Shannon R McCurdy, Monzr M. Al Malki, Ravi Varadhan, Haris Ali, Vikas Gupta, Richard J. Jones, Salman Otoukesh

https://doi.org/10.3324/haematol.2023.283426

Non-Hodgkin Lymphoma

Long non-coding RNA mitophagy and ALK-negative anaplastic lymphoma-associated transcript: a novel regulator of mitophagy in T-cell lymphoma (1115 Online Views)

Valentina Mularoni, Benedetta Donati, Annalisa Tameni, Veronica Manicardi, Francesca Reggiani, Elisabetta Sauta, Magda Zanelli, Marco Tigano, Emanuele Vitale, Federica Torricelli, Stefano Ascani, Giovanni Martino, Giorgio Inghirami, Francesca Sanguedolce, Alessia Ruffini, Alberto Bavieri, Stefano Luminari, Marco Pizzi, Angelo Paolo Dei Tos, Cinzia Fesce, Antonino Neri, Alessia Ciarrocchi, Valentina Fragliasso

https://doi.org/10.3324/haematol.2022.282552

Hodgkin Lymphoma

B-cell receptor reactivity against Rothia mucilaginosa in nodular lymphocyte-predominant Hodgkin lymphoma (1472 Online Views)

Lorenz Thurner, Natalie Fadle, Evi Regitz, Sophie Roth, Onur Cetin, Igor Age Kos, Simon Mauro Hess, Julia Bein, Rainer Maria Bohle, Martine Vornanen, Christer Sundström, Laurence de Leval, Enrico Tiacci, Peter Borchmann, Andreas Engert, Viola Poeschel, Gerhard Held, Eva C. Schwarz, Frank Neumann, Klaus-Dieter Preuss, Markus Hoth, Ralf Küppers, Karola Lehman, Martin-Leo Hansmann, Sören L. Becker, Moritz Bewarder, Sylvia Hartmann

https://doi.org/10.3324/haematol.2023.282698

Plasma Cell Disorders

Amyloidogenic light chains impair plasma cell survival (865 Online Views)

Marjorie Pick, Eyal Lebel, Sharona Elgavish, Hadar Benyamini, Yuval Nevo, Rachel Hertz, Jacob Bar-Tana, Paola Rognoni, Giampaolo Merlini, Moshe E. Gatt

https://doi.org/10.3324/haematol.2022.282484

IL6Myc mouse is an immunocompetent model for the development of aggressive multiple myeloma (817 Online Views)

Michael D. Pisano, Fumou Sun, Yan Cheng, Deepak Parashar, Vivian Zhou, Xuefang Jing, Ramakrishna Sompallae, Jenica Abrudan, Michael T. Zimmermann, Angela Mathison, Siegfried Janz, Miles A. Pufall

https://doi.org/10.3324/haematol.2022.282538

Cancer-specific mortality in multiple myeloma: a population-based retrospective cohort study (944 Online Views)

Arleigh McCurdy, Hsien Seow, Gregory P. Pond, Anastasia Gayowsky, Rajshekhar Chakraborty, Alissa Visram, Rayan Kaedbey, Anita D’Souza, Ghulam Rehman Mohyuddin, Tanya M. Wildes, Rafael Fonseca, Hira Mian

https://doi.org/10.3324/haematol.2023.282905

Disease associations with monoclonal gammopathy of undetermined significance can only be evaluated using screened cohorts: results from the population-based iStopMM study (1425 Online Views)

Aðalbjörg Ýr Sigurbergsdóttir, Sæmundur Rögnvaldsson, Sigrún Thorsteinsdóttir, Ingigerður Sverrisdóttir, Guðrún Ásta Sigurðardóttir, Brynjar Viðarsson, Páll Torfi Önundarson, Bjarni A. Agnarsson, Margrét Sigurðardóttir, Ingunn Þorsteinsdóttir, Ísleifur Ólafsson, Ásdís Rósa Þórðardóttir, Gauti Kjartan Gíslason, Andri Ólafsson, Malin Hultcrantz, Brian G. M. Durie, Stephen Harding, Ola Landgren, Thorvarður Jón Löve, Sigurður Yngvi Kristinsson

https://doi.org/10.3324/haematol.2023.283191

Changing trends in the risk factors for second primary malignancies after autologous stem cell transplantation for multiple myeloma before and after the introduction of proteasome inhibitors and immunomodulatory drugs (1130 Online Views)

Hiroyuki Takamatsu, Tomohiro Matsuda, Shohei Mizuno, Tsutomu Takahashi, Shin-ichi Fuchida, Ichiro Hanamura, Keisuke Kataoka, Nobuhiro Tsukada, Morio Matsumoto, Akira Hangaishi, Noriko Doki, Naoyuki Uchida, Masashi Sawa, Yumiko Maruyama, Shingo Kurahashi, Koji Nagafuji, Yoriko Harazaki, Shinichi Kako, Shinsuke Iida, Tatsuo Ichinohe, Yoshinobu Kanda, Yoshiko Atsuta, Kazutaka Sunami; Multiple Myeloma Working Group in the Japanese Society for Transplantation and Cellular Therapy (Collaborative Group)

https://doi.org/10.3324/haematol.2023.283202

Red Cell Biology & its Disorders

Early splenectomy in a large cohort of children with sickle cell anemia: risks and consequences (1118 Online Views)

Aimen Mechraoui, Ghislaine Ithier, Justine Pages, Zinedine Haouari, Liza Ali, Arnaud Bonnard, Malika Benkerrou, Florence Missud, Berengère Koehl, Laurent Holvoet, Enora Le Roux, Valentine Brousse

https://doi.org/10.3324/haematol.2022.282556

Metabolic signatures of cardiorenal dysfunction in plasma from sickle cell patients as a function of therapeutic transfusion and hydroxyurea treatment (1214 Online Views)

Angelo D’Alessandro, S. Mehdi Nouraie, Yingze Zhang, Francesca Cendali, Fabia Gamboni, Julie A. Reisz, Xu Zhang, Kyle W. Bartsch, Matthew D. Galbraith, Joaquin M. Espinosa, Victor R. Gordeuk, Mark T. Gladwin

https://doi.org/10.3324/haematol.2023.283288

Letters to the Editor

Prognostic value of early positron emission tomography in patients with large B-cell lymphoma treated with anti-CD19 chimeric antigen receptor T-cell therapy (1200 Online Views)

Jennifer L. Crombie, Caron A. Jacobson, Robert Redd, Geoffrey Shouse, Alex F. Herrera, Victor A. Chow, Jordan Gauthier, Erin Mullane, Kirk Cahill, Justin Kline, Jason Romancik, Jonathon B. Cohen, Anna Saucier, Roch Houot, Philippe Armand, Brian Hess

https://doi.org/10.3324/haematol.2022.282345

Hematological abnormalities in Jacobsen syndrome: cytopenia of varying severities and morphological abnormalities in peripheral blood and bone marrow (867 Online Views)

Daiki Yamashita, Hideki Muramatsu, Atsushi Narita, Manabu Wakamatsu, Yusuke Tsumura, Daichi Sajiki, Ryo Maemura, Ayako Yamamori, Masayuki Imaya, Kotaro Narita, Shinsuke Kataoka, Rieko Taniguchi, Nobuhiro Nishio, Yusuke Okuno, Naoto Fujita, Katsuyoshi Koh, Katsutsugu Umeda, Eiji Morihana, Hideto Iwafuchi, Masafumi Ito, Seiji Kojima, Asahito Hama, Yoshiyuki Takahashi

https://doi.org/10.3324/haematol.2022.282513

Specific blood monocyte distribution in histiocytoses correlates with vascular involvement and disease activity (704 Online Views)

Jerome Razanamahery, Maxime Samson, Julien Guy, Jessica Racine, Celine Row, Hélène Greigert, Barbara Nicolas, Stephanie Francois, Jean-François Emile, Fleur Cohen-Aubart, Sylvain Audia, Julien Haroche, Bernard Bonnotte

https://doi.org/10.3324/haematol.2023.282739

Mechanisms of endothelial injury and transplant-associated thrombotic microangiopathy in tandem autologous hematopoietic stem cell transplant for neuroblastoma (885 Online Views)

Anthony Sabulski, Sheyar Abdullah, Nathan Luebbering, Benjamin Aunins, Caitlin Castillo, Kelly Lake, Alexandra Duell, Lauren Strecker, Lucille Langenberg, William Broomhead, Scott DiMeo, Elizabeth A. Odegard, Jason T. Blackard, Assem G. Ziady, Alix E. Seif, Christopher E. Dandoy, Benjamin L. Laskin, Sonata Jodele, Stella M. Davies

https://doi.org/10.3324/haematol.2023.283351

Cross-intolerance with bosutinib after prior tyrosine kinase inhibitors for Philadelphia chromosome-positive leukemia: long-term analysis of a phase I/II study (1341 Online Views)

Jorge E. Cortes, Jeff H. Lipton, Vamsi Kota, Fausto Castagnetti, Sarit Assouline, Tim H. Brümmendorf, Eric Leip, Andrea Viqueira, Carlo Gambacorti-Passerini

https://doi.org/10.3324/haematol.2022.281944

Efficacy and toxicity of midostaurin with idarubicin and cytarabine induction in FLT3-mutated acute myeloid leukemia (777 Online Views)

Julia S. Lee, Charlotte B. Wagner, Stacy Prelewicz, Heena P. Kurish, Robert Walchack, Danielle A. Cenin, Seema Patel, Mimi Lo, Danielle Schlafer, Belinda K.T. Li, R. Donald Harvey III, Bestis Wasef, Jian Ying, Tibor Kovacsovics

https://doi.org/10.3324/haematol.2022.281967

Latexin deletion protects against radiation-induced hematopoietic damages via selective activation of Bcl-2 prosurvival pathway (623 Online Views)

Cuiping Zhang, Xiaojing Cui, Yi Liu, Fang Wang, Robert Signer, Kapana Nattamai, Daohong Zhou, Yi Zheng, Hartmut Geiger, Fengyi Wan, Ying Liang

https://doi.org/10.3324/haematol.2022.282028

ETV6 fusions from insertions of exons 3-5 in pediatric hematologic malignancies (595 Online Views)

Sarah B. Mueller, Yana Pikman, Sarah K. Tasian, Lewis B. Silverman, Marian H. Harris, Harrison K. Tsai

https://doi.org/10.3324/haematol.2022.282498

Modified carfilzomib dosing is associated with improved treatment responses and longer time on treatment in patients with multiple myeloma (1151 Online Views)

Abdullah M. Khan, Kiatlyn Dvorak, Qiuhong Zhao, Naresh Bumma, Francesca Cottini, Srinivas Devarakonda, Elvira Umyarova, Nidhi Sharma, Don Benson, Ashley Rosko

https://doi.org/10.3324/haematol.2022.282521

CAR T-cell therapy for central nervous system lymphomas: blood and cerebrospinal fluid biology, and outcomes (1194 Online Views)

Claire Lacan, Jonathan Caron, Nadine Tarantino, Baptiste Fouquet, Mustapha Cherai, Christophe Parizot, Véronique Morel, Laetitia Souchet, Madalina Uzunov, Guy Gorochov, Stéphanie Nguyen-Quoc, Elise Sourdeau, Vincent Vieillard, Makoto Miyara, Angélique Vinit, Silvia Solorzano, Carole Soussain, Caroline Houillier, Carole Metz, Brigitte Autran, Elena Litvinova, Magali Le Garff-Tavernier, Françoise Norol, Damien Roos-Weil, Sylvan Choquet, Amélie Guihot, Marine Baron

https://doi.org/10.3324/haematol.2023.282875

CD47 expression in acute myeloid leukemia varies according to genotype (2185 Online Views)

Andrea Marra, Ayse U Akarca, Giovanni Martino, Alan Ramsay, Stefano Ascani, Vincenzo Maria Perriello, Jenny O’Nions, Andrew J Wilson, Rajeev Gupta, Anna Childerhouse, Ian Proctor, Manuel Rodriguez-Justo, Sabine Pomplun, Maria Paola Martelli, Cristina Lo Celso, Brunangelo Falini, Teresa Marafioti

https://doi.org/10.3324/haematol.2023.283154

Co-stimulatory and immune checkpoint molecules are important in the tumor microenvironment of Hodgkin-like adult T-cell leukemia/lymphoma (630 Online Views)

Mai Takeuchi, Hiroaki Miyoshi, Yuichiro Semba, Kyohei Yamada, Kazutaka Nakashima, Kensaku Sato, Takuya Furuta, Mayuko Moritsubo, Yusuke Ogura, Ken Tanaka, Teppei Imamoto, Fumiko Arakawa, Kei Kohno, Koichi Ohshima

https://doi.org/10.3324/haematol.2023.283163

Higher cyclophosphamide dose grants optimal stem cell collection after daratumumab-based induction in multiple myeloma (1109 Online Views)

Carmine Liberatore, Tommaso Perini, Cecilia Passeri, Valeria Ferla, Francesca Fioritoni, Virginia Girlando, Ornella Iuliani, Alessia Orsini, Guido Montanaro, Francesca Farina, Alessandro Di Nicola, Rosamaria Nitti, Stefano Pulini, Sara Mastaglio, Stella Santarone, Milena Coppola, Sarah Marktel, Patrizia Accorsi, Fabio Ciceri, Magda Marcatti, Mauro Di Ianni

https://doi.org/10.3324/haematol.2023.283452

Case Reports

Myeloid lineage switch following CD7-targeted chimeric antigen receptor T-cell therapy in relapsed/refractory T-cell acute lymphoblastic leukemia (1796 Online Views)

Ibrahim Aldoss, Parastou Tizro, Davsheen Bedi, James K. Mangan, Mary C. Clark, David Spencer, Joo Y. Song, Sindhu Cherian, Raju Pillai, Young Kim, Nitin Mahajan, Ketevan Gendzekhadze, Mike James, Kenneth Jacobs, Jan Davidson-Moncada, Stephen J. Forman, Huan-You Wang, Michelle Afkhami

https://doi.org/10.3324/haematol.2023.283566