July, 2022
No. 107 (7)

About the Cover

Landmark papers in Hematology

Editorials

Review Articles

Articles

Acute Myeloid Leukemia

A risk score based on real-world data to predict early death in acute promyelocytic leukemia (3523 Online Views)

Albin Österroos, Tânia Maia, Anna Eriksson, Martin Jädersten, Vladimir Lazarevic, Lovisa Wennström, Petar Antunovic, Jörg Cammenga, Stefan Deneberg, Fryderyk Lorenz, Lars Möllgård, Bertil Uggla, Emma Ölander, Eliana Aguiar, Fernanda Trigo, Martin Höglund, Gunnar Juliusson, Sören Lehmann

https://doi.org/10.3324/haematol.2021.280093

Cell Therapy and Immunotherapy

Therapeutic targeting of endoplasmic reticulum stress in acute graft-versus-host disease (2893 Online Views)

Eileen Haring, Geoffroy Andrieux, Franziska M. Uhl, Máté Krausz, Michele Proietti, Barbara Sauer, Philipp R. Esser, Stefan F. Martin, Dietmar Pfeifer, Annette Schmitt-Graeff, Justus Duyster, Natalie Köhler, Bodo Grimbacher, Melanie Boerries, Konrad Aumann, Robert Zeiser, Petya Apostolova

https://doi.org/10.3324/haematol.2021.278387

Cardiovascular events in patients treated with chimeric antigen receptor T-cell therapy for aggressive B-cell lymphoma (6277 Online Views)

Raphael E. Steiner, Jose Banchs, Efstratios Koutroumpakis, Melody Becnel, Cristina Gutierrez, Paolo Strati, Chelsea C. Pinnix, Lei Feng, Gabriela Rondon, Catherine Claussen, Nicolas Palaskas, Kaveh Karimzad, Sairah Ahmed, Sattva S. Neelapu, Elizabeth Shpall, Michael Wang, Francisco Vega, Jason Westin, Loretta J. Nastoupil, Anita Deswal

https://doi.org/10.3324/haematol.2021.280009

Hemostasis

Renal function and clinical outcome of patients with cancer-associated venous thromboembolism randomized to receive apixaban or dalteparin. Results from the Caravaggio trial (3098 Online Views)

Cecilia Becattini, Rupert Bauersachs, Giorgio Maraziti, Laurent Bertoletti, Alexander Cohen, Jean M. Connors, Dario Manfellotto, Antonio Sanchez, Benjamin Brenner, Giancarlo Agnelli

https://doi.org/10.3324/haematol.2021.279072

Hemoglobinopathies

Genetic modifiers of fetal hemoglobin affect the course of sickle cell disease in patients treated with hydroxyurea (2382 Online Views)

Pierre Allard, Nareen Alhaj, Stephan Lobitz, Holger Cario, Andreas Jarisch, Regine Grosse, Lena Oevermann, Dani Hakimeh, Laura Tagliaferri, Elisabeth Kohne, Annette Kopp-Schneider, Andreas E. Kulozik, Joachim B. Kunz

https://doi.org/10.3324/haematol.2021.278952

Iron Metabolism & its Disorders

Hepcidin regulation in Kenyan children with severe malaria and non-typhoidal Salmonella bacteremia (5027 Online Views)

Kelvin M. Abuga, John Muthii Muriuki, Sophie M. Uyoga, Kennedy Mwai, Johnstone Makale, Reagan M. Mogire, Alex W. Macharia, Shebe Mohammed, Esther Muthumbi, Salim Mwarumba, Neema Mturi, Philip Bejon, J. Anthony G. Scott, Manfred Nairz, Thomas N. Williams, Sarah H. Atkinson

https://doi.org/10.3324/haematol.2021.279316

Myeloproliferative Disorders

Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia (4606 Online Views)

Srdan Verstovsek, Ruben Mesa, Moshe Talpaz, Jean-Jacques Kiladjian, Claire N. Harrison, Stephen T. Oh, Alessandro M. Vannucchi, Raajit Rampal, Bart L. Scott, Sarah A. Buckley, Adam R. Craig, Karisse Roman-Torres, John O. Mascarenhas

https://doi.org/10.3324/haematol.2021.279415

Non-Hodgkin Lymphoma

Phase I/II clinical trial of temsirolimus and lenalidomide in patients with relapsed and refractory lymphomas (3335 Online Views)

Ajay Major, Justin Kline, Theodore G. Karrison, Paul A. S. Fishkin, Amy S. Kimball, Adam M. Petrich, Sreenivasa Nattam, Krishna Rao, Bethany G. Sleckman, Kenneth Cohen, Koen van Besien, Aaron P. Rapoport, Sonali M. Smith

https://doi.org/10.3324/haematol.2021.278853

Whole-genome profiling of primary cutaneous anaplastic large cell lymphoma (3633 Online Views)

Armando N. Bastidas Torres, Rutger C. Melchers, Liana van Grieken, Jacoba J. Out-Luiting, Hailiang Mei, Cedrick Agaser, Thomas B. Kuipers, Koen D. Quint, Rein Willemze, Maarten H. Vermeer, Cornelis P. Tensen

https://doi.org/10.3324/haematol.2020.263251

Total metabolic tumor volume as a survival predictor for patients with diffuse large B-cell lymphoma in the GOYA study (2609 Online Views)

Lale Kostakoglu, Federico Mattiello, Maurizio Martelli, Laurie H. Sehn, David Belada, Chiara Ghiggi, Neil Chua, Eva González-Barca, Xiaonan Hong, Antonio Pinto, Yuankai Shi, Yoichi Tatsumi, Christopher Bolen, Andrea Knapp, Gila Sellam, Tina Nielsen, Deniz Sahin, Umberto Vitolo, Marek Trněný

https://doi.org/10.3324/haematol.2021.278663

Platelet Biology & its Disorders

Establishment of a Bernard-Soulier syndrome model in zebrafish (2974 Online Views)

Qing Lin, Riyang Zhou, Panpan Meng, Liangliang Wu, Lian Yang, Wenyu Liu, Jiaye Wu, Yuhuan Cheng, Linjuan Shi, Yiyue Zhang

https://doi.org/10.3324/haematol.2021.278893

Single platelet and megakaryocyte morpho-dynamics uncovered by multicolor reporter mouse strains in vitro and in vivo (2697 Online Views)

Leo Nicolai, Rainer Kaiser, Raphael Escaig, Marie-Louise Hoffknecht, Afra Anjum, Alexander Leunig, Joachim Pircher, Andreas Ehrlich, Michael Lorenz, Hellen Ishikawa-Ankerhold, William C. Aird, Steffen Massberg, Florian Gaertner

https://doi.org/10.3324/haematol.2021.278896

Letters to the Editor

Outcomes of refractory or relapsed Hodgkin lymphoma patients with post-autologous stem cell transplantation brentuximab vedotin maintenance: a French multicenter observational cohort study (2731 Online Views)

Amira Marouf, Anne Segolene Cottereau, Salim Kanoun, Paul Deschamps, Michel Meignan, Patricia Franchi, David Sibon, Clara Antoine, Thomas Gastinne, Cecile Borel, Mohammad Hammoud, Guillaume Sicard, Romane Gille, Doriane Cavalieri, Aspasia Stamatoullas, Lauriane Filliatre-Clement, Julien Lazarovici, Adrien Chauchet, Luc-Matthieu Fornecker, Sandy Amorin, Mathieu Rocquet, Nicole Raus, Barbara Burroni, Marie Therese Rubio, Didier Bouscary, Philippe Quittet, Rene Olivier Casasnovas, Pauline Brice, Herve Ghesquieres, Jérôme Tamburini, Benedicte Deau

https://doi.org/10.3324/haematol.2021.279564

Vaccine-induced immune thrombotic thrombocytopenia: a possible pathogenic role of ChAdOx1 nCoV-19 vaccine-encoded soluble SARS-CoV-2 spike protein (1425 Online Views)

Manuela De Michele, Paola Piscopo, Alessio Crestini, Roberto Rivabene, Giulia d’Amati, Martina Leopizzi, Lucia Stefanini, Fabio Pulcinelli, Antonio Chistolini, Marta Iacobucci, Oscar G. Schiavo, Irene Berto, Ettore Nicolini, Luca Petraglia, Maria Teresa Di Mascio, Danilo Toni

https://doi.org/10.3324/haematol.2021.280180

All-oral triplet combination of ixazomib, lenalidomide, and dexamethasone in newly diagnosed transplant-eligible multiple myeloma patients: final results of the phase II IFM 2013-06 study (2330 Online Views)

Cyrille Touzeau, Aurore Perrot, Murielle Roussel, Lionel Karlin, Lotfi Benboubker, Caroline Jacquet, Mohamad Mohty, Thierry Facon, Salomon Manier, Marie-Lorraine Chretien, Mourad Tiab, Cyrille Hulin, Xavier Leleu, Hervé Avet Loiseau, Thomas Dejoie, Lucie Planche, Michel Attal, Philippe Moreau

https://doi.org/10.3324/haematol.2021.280394

Complement C1s inhibition with sutimlimab results in durable response in cold agglutinin disease: CARDINAL study 1-year interim follow-up results (4041 Online Views)

Alexander Roth, Wilma Barcellini, Shirley D’Sa, Yoshitaka Miyakawa, Catherine M. Broome, Marc Michel, David J. Kuter, Bernd Jilma, Tor Henrik Anderson Tvedt, Ilene C. Weitz, Parija Patel, Xiaoyu Jiang, Caroline Reuter, Jun Su, Frank Shafer, Michelle Lee, Sigbjorn Berentsen

https://doi.org/10.3324/haematol.2021.279812

Decitabine salvage for TP53-mutated, relapsed/refractory acute myeloid leukemia after cytotoxic induction therapy (2010 Online Views)

Francesca Ferraro, Agata Gruszczynska, Marianna B. Ruzinova, Christopher A. Miller, Mary Elizabeth Percival, Geoffrey L. Uy, Iskra Pusic, Meagan A. Jacoby, Mathew J. Christopher, Miriam Y. Kim, Peter Westervelt, Amanda F. Cashen, Mark A. Schroeder, John F. DiPersio, Camille N. Abboud, Lukas D. Wartman, Feng Gao, Daniel C. Link, Timothy J. Ley, John S. Welch

https://doi.org/10.3324/haematol.2021.280153

Tricuspid-valve regurgitant jet velocity as a risk factor for death in β-thalassemia (2288 Online Views)

Giorgio Derchi, Khaled M. Musallam, Valeria Maria Pinto, Giovanna Graziadei, Marianna Giuditta, Susanna Barella, Raffaella Origa, Gavino Casu, Annamaria Pasanisi, Filomena Longo, Maddalena Casale, Roberta Miceli, Pierluigi Merella, Barbara Gianesin, Pietro Ameri, Immacolata Tartaglione, Silverio Perrotta, Antonio Piga, Maria Domenica Cappellini, Gian Luca Forni

https://doi.org/10.3324/haematol.2021.280389

BRAF V600E-positive cells as molecular markers of bone marrow disease in pediatric Langerhans cell histiocytosis (1984 Online Views)

Ko Kudo, Tsutomu Toki, Rika Kanezaki, Tatsuhiko Tanaka, Takuya Kamio, Tomohiko Sato, Shinya Sasaki, Masaru Imamura, Chihaya Imai, Kumiko Ando, Harumi Kakuda, Takehiko Doi, Hiroshi Kawaguchi, Masahiro Irie, Yoji Sasahara, Akihiro Tamura, Daiichiro Hasegawa, Yosuke Itakura, Kenichiro Watanabe, Kenichi Sakamoto, Yoko Shioda, Motohiro Kato, Kazuko Kudo, Reiji Fukano, Atsushi Sato, Hiroshi Yagasaki, Hirokazu Kanegane, Itaru Kato, Katsutsugu Umeda, Souichi Adachi, Tatsuki Kataoka, Akira Kurose, Atsuko Nakazawa, Kiminori Terui, Etsuro Ito

https://doi.org/10.3324/haematol.2021.279857

Treatment emergent peripheral neuropathy in the CASSIOPEIA trial (1952 Online Views)

Cathelijne Fokkema, Phillipe Moreau, Bronno van der Holt, Jérôme Lambert, Mark van Duin, Ruth Wester, Joost L.M. Jongen, Pieter A. van Doorn, Sophie Godet, Kon Siong Jie, Olivier Fitoussi, Michel Delforge, Awa Keita-Manta, Odile Luycx, Tom Cupedo, Niels W.C.J. van de Donk, Sonja Zweegman, Jessica T. Vermeulen, Pieter Sonneveld, Annemiek Broijl

https://doi.org/10.3324/haematol.2021.280567

Prolonged viral replication in patients with hematologic malignancies hospitalized with COVID-19 (3011 Online Views)

Carolina Garcia-Vidal, Pedro Puerta-Alcalde, Aina Mateu, Genoveva Cuesta-Chasco, Fernanda Meira, Carlos Lopera, Patricia Monzo, Marta Santos-Bravo, Gerard Duenas, Mariana Chumbita, Nicole Garcia-Pouton, Anna Gaya, Marta Bodro, Sabina Herrera, Mar Mosquera, Francesc Fernandez-Aviles, Jose Antonio Martinez, Josep Mensa, Eva Gine, Maria Angeles Marcos, Alex Soriano

https://doi.org/10.3324/haematol.2021.280407