Vol. 104 No. 11 (2019): November, 2019

Lijian Shao, Kilian Sottoriva, Karol Palasiewicz, Jizhou Zhang, James Hyun, Sweta S. Soni, Na Yoon Paik, Xiaopei Gao, Henar Cuervo, Asrar B. Malik, Jalees Rehman, Daniel Lucas, Kostandin V. Pajcini

https://doi.org/10.3324/haematol.2018.208660

Deubiquitylase USP7 regulates human terminal erythroid differentiation by stabilizing GATA1 (2717 Online Views)

Long Liang, Yuanliang Peng, Jieying Zhang, Yibin Zhang, Mridul Roy, Xu Han, Xiaojuan Xiao, Shuming Sun, Hong Liu, Ling Nie, Yijin Kuang, Zesen Zhu, Jinghui Deng, Yang Xia, Vijay G. Sankaran, Christopher D. Hillyer, Narla Mohandas, Mao Ye, Xiuli An, Jing Liu

https://doi.org/10.3324/haematol.2018.206227

Altered parasite life-cycle processes characterize Babesia divergens infection in human sickle cell anemia (3064 Online Views)

Jeny R. Cursino-Santos, Manpreet Singh, Eric Senaldi, Deepa Manwani, Karina Yazdanbakhsh, Cheryl A. Lobo

https://doi.org/10.3324/haematol.2018.214304

Distinguishing essential thrombocythemia JAK2V617F from polycythemia vera: limitations of erythrocyte values (2704 Online Views)

Richard T. Silver, Spencer Krichevsky

https://doi.org/10.3324/haematol.2018.213108

MR4 sustained for 12 months is associated with stable deep molecular responses in chronic myeloid leukemia (4713 Online Views)

Simone Claudiani, Aoife Gatenby, Richard Szydlo, George Nesr, Adi Shacham Abulafia, Renuka Palanicawandar, Georgios Nteliopoulos, Jamshid Khorashad, Letizia Foroni, Jane F. Apperley, Dragana Milojkovic

https://doi.org/10.3324/haematol.2018.214809

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation (2093 Online Views)

Cristina Di Genua, Ruggiero Norfo, Alba Rodriguez-Meira, Wei Xiong Wen, Roy Drissen, Christopher A.G. Booth, Benjamin Povinelli, Emmanouela Repapi, Nicki Gray, Joana Carrelha, Laura M. Kettyle, Lauren Jamieson, Wen Hao Neo, Supat Thongjuea, Claus Nerlov, Adam J. Mead

https://doi.org/10.3324/haematol.2018.205351

Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia (2142 Online Views)

Xinyu Li, Yongwei Su, Gerard Madlambayan, Holly Edwards, Lisa Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Jun Ma, Tristan Knight, Guan Wang, Yue Wang, Jay Yang, Jeffrey W. Taub, Hai Lin, Yubin Ge

https://doi.org/10.3324/haematol.2018.201343

Prolonged survival in the absence of disease-recurrence in advanced-stage follicular lymphoma following chemo-immunotherapy: 13-year update of the prospective, multicenter randomized GITMO-IIL trial (5557 Online Views)

Riccardo Bruna, Fabio Benedetti, Carola Boccomini, Caterina Patti, Anna Maria Barbui, Alessandro Pulsoni, Maurizio Musso, Anna Marina Liberati, Guido Gini, Claudia Castellino, Fausto Rossini, Fabio Ciceri, Delia Rota-Scalabrini, Caterina Stelitano, Francesco Di Raimondo, Alessandra Tucci, Liliana Devizzi, Valerio Zoli, Francesco Zallio, Franco Narni, Alessandra Dondi, Guido Parvis, Gianpietro Semenzato, Francesco Lanza, Tommasina Perrone, Francesco Angrilli, Atto Billio, Angela Gueli, Barbara Mantoan, Alessandro Rambaldi, Alessandro Massimo Gianni, Paolo Corradini, Roberto Passera, Marco Ladetto, Corrado Tarella

https://doi.org/10.3324/haematol.2018.209932

High prognostic value of measurable residual disease detection by flow cytometry in chronic lymphocytic leukemia patients treated with front-line fludarabine, cyclophosphamide, and rituximab, followed by three years of rituximab maintenance (1967 Online Views)

José A. García-Marco, Javier López Jiménez, Valle Recasens, Miguel Fernández Zarzoso, Eva González-Barca, Nieves Somolinos De Marcos, M. Jose Ramírez, Francisco Javier Peñalver Parraga, Lucrecia Yañez, Javier De La Serna Torroba, Maria Dolores Garcia Malo, Guillermo Deben Ariznavarreta, Ernesto Perez Persona, M. Angeles Ruiz Guinaldo, Raquel De Paz Arias, Elena Bañas Llanos, Isidro Jarque, M. del Carmen Fernandez Valle, Ana Carral Tatay, Jaime Perez De Oteyza, Eva Maria Donato Martin, Inmaculada Perez Fernández, Rafael Martinez Martinez, M. Angeles Andreu Costa, Diana Champ, Julio García Suarez, Marcos González Díaz, Secundino Ferrer, Félix Carbonell, José A. García-Vela

https://doi.org/10.3324/haematol.2018.204891

Utility of positron emission tomography-computed tomography in patients with chronic lymphocytic leukemia following B-cell receptor pathway inhibitor therapy (1917 Online Views)

Anthony R. Mato, William G. Wierda, Matthew S. Davids, Bruce D. Cheson, Steven E. Coutre, Michael Choi, Richard R. Furman, Leonard Heffner, Paul M. Barr, Herbert Eradat, Sharanya M. Ford, Lang Zhou, Maria Verdugo, Rod A. Humerickhouse, Jalaja Potluri, John C. Byrd

https://doi.org/10.3324/haematol.2018.207068

Phase II study of carfilzomib, thalidomide, and low-dose dexamethasone as induction and consolidation in newly diagnosed, transplant eligible patients with multiple myeloma; the Carthadex trial (2558 Online Views)

Ruth Wester, Bronno van der Holt, Emelie Asselbergs, Sonja Zweegman, Marie Jose Kersten, Edo Vellenga, Marinus van Marwijk Kooy, Okke de Weerdt, Monique Minnema, Sarah Lonergan, Antonio Palumbo, Henk Lokhorst, Annemiek Broijl, Pieter Sonneveld

https://doi.org/10.3324/haematol.2018.205476

Bortezomib-based induction followed by stem cell transplantation in light chain amyloidosis: results of the multicenter HOVON 104 trial (1654 Online Views)

Monique C. Minnema, Kazem Nasserinejad, Bouke Hazenberg, Ute Hegenbart, Philip Vlummens, Paula F. Ypma, Nicolaus Kröger, Ka Lung Wu, Marie Jose Kersten, M. Ron Schaafsma, Sandra Croockewit, Esther de Waal, Sonja Zweegman, Lidwien Tick, Annemieke Broijl, Harry Koene, Gerard Bos, Pieter Sonneveld, Stefan Schönland

https://doi.org/10.3324/haematol.2018.213900

Long-term treatment with romiplostim and treatment-free platelet responses in children with chronic immune thrombocytopenia (3091 Online Views)

Michael D. Tarantino, James B. Bussel, Victor S. Blanchette, Donald Beam, John Roy, Jenny Despotovic, Ashok Raj, Nancy Carpenter, Bhakti Mehta, Melissa Eisen

https://doi.org/10.3324/haematol.2018.202283

Differences and similarities in the effects of ibrutinib and acalabrutinib on platelet functions (5143 Online Views)

Jennifer Series, Cédric Garcia, Marie Levade, Julien Viaud, Pierre Sié, Loïc Ysebaert, Bernard Payrastre

https://doi.org/10.3324/haematol.2018.207183

Dynamic prediction of bleeding risk in thrombocytopenic preterm neonates (1444 Online Views)

Susanna F. Fustolo-Gunnink, Karin Fijnvandraat, Hein Putter, Isabelle M. Ree, Camila Caram-Deelder, Peter Andriessen, Esther J. d’Haens, Christian V. Hulzebos, Wes Onland, André A. Kroon, Daniël C. Vijlbrief, Enrico Lopriore, Johanna G. van der Bom

https://doi.org/10.3324/haematol.2018.208595

Christmas disease in a Hovawart family resembling human hemophilia B Leyden is caused by a single nucleotide deletion in a highly conserved transcription factor binding site of the F9 gene promoter (1792 Online Views)

Bertram Brenig, Lilith Steingräber, Shuwen Shan, Fangzheng Xu, Marc Hirschfeld, Reiner Andag, Mirjam Spengeler, Elisabeth Dietschi, Reinhard Mischke, Tosso Leeb

https://doi.org/10.3324/haematol.2018.215426

Role of interferon-γ in immune-mediated graft failure after allogeneic hematopoietic stem cell transplantation (2745 Online Views)

Pietro Merli, Ignazio Caruana, Rita De Vito, Luisa Strocchio, Gerrit Weber, Francesca Del Bufalo, Vanessa Buatois, Paolo Montanari, Maria Giuseppina Cefalo, Angela Pitisci, Mattia Algeri, Federica Galaverna, Concetta Quintarelli, Valentina Cirillo, Daria Pagliara, Walter Ferlin, Maria Ballabio, Cristina De Min, Franco Locatelli

https://doi.org/10.3324/haematol.2019.216101

Guidelines from the 2017 European Conference on Infections in Leukaemia for management of HHV-6 infection in patients with hematologic malignancies and after hematopoietic stem cell transplantation (18903 Online Views)

Katherine N Ward, Joshua A Hill, Petr Hubacek, Rafael de la Camara, Roberto Crocchiolo, Hermann Einsele, David Navarro, Christine Robin, Catherine Cordonnier, Per Ljungman

https://doi.org/10.3324/haematol.2019.223073

Clinical and morphological predictors of outcome in older aplastic anemia patients treated with eltrombopag (1258 Online Views)

Bruno Fattizzo, Austin G. Kulasekararaj, Anita Hill, Nana Benson-Quarm, Morag Griffin, Talha Munir, Louise Arnold, Kathryn Riley, Robin Ireland, Hugues De Lavallade, Victoria Potter, Dario Consonni, Peter Hillmen, Ghulam J. Mufti, Wilma Barcellini, Judith C. W. Marsh

https://doi.org/10.3324/haematol.2019.216374

Correction of IVS I-110(G>A) β-thalassemia by CRISPR/Cas-and TALEN-mediated disruption of aberrant regulatory elements in human hematopoietic stem and progenitor cells (3296 Online Views)

Petros Patsali, Giandomenico Turchiano, Panayiota Papasavva, Marianna Romito, Constantinos C. Loucari, Coralea Stephanou, Soteroulla Christou, Maria Sitarou, Claudio Mussolino, Tatjana I. Cornu, Michael N. Antoniou, Carsten W. Lederer, Toni Cathomen, Marina Kleanthous

https://doi.org/10.3324/haematol.2018.215178

Autoimmunity associated with Erdheim-Chester disease improves with BRAF/MEK inhibitors (733 Online Views)

Anaïs Roeser, Fleur Cohen-Aubart, Paul Breillat, Makoto Miyara, Jean-François Emile, Frédéric Charlotte, Jean Donadieu, Zahir Amoura, Julien Haroche

https://doi.org/10.3324/haematol.2018.214007

Evidence for prevention of renal dysfunction associated with primary myelofibrosis by cytoreductive therapy (1568 Online Views)

Yasutaka Fukuda, Marito Araki, Kouji Yamamoto, Soji Morishita, Tadaaki Inano, Kyohei Misawa, Tomonori Ochiai, Yoko Edahiro, Misa Imai, Hajime Yasuda, Akihiko Gotoh, Akimichi Ohsaka, Norio Komatsu

https://doi.org/10.3324/haematol.2018.208876

Response assessment in acute myeloid leukemia by flow cytometry supersedes cytomorphology at time of aplasia, amends cases without molecular residual disease marker and serves as an independent prognostic marker at time of aplasia and post-induction (1086 Online Views)

Thomas Köhnke, Veit Bücklein, Sandra Rechkemmer, Stephanie Schneider, Maja Rothenberg-Thurley, Klaus H. Metzeler, Maria-Cristina Sauerland, Wolfgang Hiddemann, Karsten Spiekermann, Marion Subklewe

https://doi.org/10.3324/haematol.2018.215236

Increased neonatal level of arginase 2 in cases of childhood acute lymphoblastic leukemia implicates immunosuppression in the etiology (650 Online Views)

Amalie B. Nielsen, Mi Zhou, Adam J. de Smith, Rong Wang, Lucie McCoy, Helen Hansen, Libby Morimoto, Kirsten Grønbæk, Christoffer Johansen, Scott C. Kogan, Catherine Metayer, Paige M. Bracci, Xiaomei Ma, Joseph L. Wiemels

https://doi.org/10.3324/haematol.2019.216465

Impact of corticosteroid pretreatment in pediatric patients with newly diagnosed B-lymphoblastic leukemia: a report from the Children’s Oncology Group (1263 Online Views)

Elizabeth A. Raetz, Mignon L. Loh, Meenakshi Devidas, Kelly Maloney, Leonard A. Mattano, Eric Larsen, Andrew Carroll, Nyla A. Heerema, Julie M. Gastier-Foster, Brent Wood, Michael J. Borowitz, Naomi Winick, Stephen P. Hunger, William L. Carroll

https://doi.org/10.3324/haematol.2018.215616

PD-1 blockade as bridge to allogeneic stem cell transplantation in relapsed/refractory Hodgkin lymphoma patients: a retrospective single center case series (1422 Online Views)

Beatrice Casadei, Alessandro Broccoli, Vittorio Stefoni, Cinzia Pellegrini, Miriam Marangon, Alice Morigi, Laura Nanni, Ginevra Lolli, Matteo Carella, Lisa Argnani, Michele Cavo, Pier Luigi Zinzani

https://doi.org/10.3324/haematol.2019.215962

Possibilities and limitations of an in vitro three-dimensional bone marrow model for the prediction of clinical responses in patients with relapsed multiple myeloma (1083 Online Views)

Maaike V.J. Braham, Jacqueline Alblas, Wouter J. A. Dhert, F. Cumhur Öner, Monique C. Minnema

https://doi.org/10.3324/haematol.2018.213355

Variation of rs3754689 at lactase gene and inhibitors in admixed Brazilian patients with hemophilia A (771 Online Views)

Luciana W. Zuccherato, Silvana M. Elói-Santos, Letícia L. Jardim, Ricardo M. Camelo, Daniel G. Chaves, Renan P. Souza, Edward J. Hollox, Suely M. Rezende

https://doi.org/10.3324/haematol.2019.220608

Erdheim-Chester disease associated with chronic myelomonocytic leukemia harboring the same clonal mutation (1216 Online Views)

Pauline Bonnet, François Chasset, Philippe Moguelet, Noémie Abisror, Raphaël Itzykson, Jean-David Bouaziz, Pierre Hirsch, Annick Barbaud, Julien Haroche, Arsène Mekinian, Zofia Hélias-Rodzewicz, Emmanuelle Clappier, Pierre Fenaux, Olivier Fain, Abdellatif Tazi, Jean-François Emile

https://doi.org/10.3324/haematol.2019.223552