January, 2017
No. 102 (1)

Editorials

Review Articles

Articles

Myeloproliferative Disorders

Risk of thrombosis according to need of phlebotomies in patients with polycythemia vera treated with hydroxyurea (422 Online Views)

Alberto Alvarez-Larrán, Manuel Pérez-Encinas, Francisca Ferrer-Marín, Juan Carlos Hernández-Boluda, María José Ramírez, Joaquín Martínez-López, Elena Magro, Yasmina Cruz, María Isabel Mata, Pilar Aragües, María Laura Fox, Beatriz Cuevas, Sara Montesdeoca, José Angel Hernández-Rivas, Valentín García-Gutiérrez, María Teresa Gómez-Casares, Juan Luis Steegmann, María Antonia Durán, Montse Gómez, Ana Kerguelen, Abelardo Bárez, Mari Carmen García, Concepción Boqué, José María Raya, Clara Martínez, Manuel Albors, Francesc García, Carmen Burgaleta, Carlos Besses

https://doi.org/10.3324/haematol.2016.152769

Acute Myeloid Leukemia

Pre-transplantation minimal residual disease with cytogenetic and molecular diagnostic features improves risk stratification in acute myeloid leukemia (282 Online Views)

Betül Oran, Jeff L. Jorgensen, David Marin, Sa Wang, Sairah Ahmed, Amin M. Alousi, Borje S. Andersson, Qaiser Bashir, Roland Bassett, Genevieve Lyons, Julianne Chen, Katy Rezvani, Uday Popat, Partow Kebriaei, Keyur Patel, Gabriela Rondon, Elizabeth J. Shpall, Richard E. Champlin

https://doi.org/10.3324/haematol.2016.144253

Acute Lymphoblastic Leukemia

ZNF384-related fusion genes define a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with a characteristic immunotype (589 Online Views)

Shinsuke Hirabayashi, Kentaro Ohki, Kazuhiko Nakabayashi, Hitoshi Ichikawa, Yukihide Momozawa, Kohji Okamura, Akinori Yaguchi, Kazuki Terada, Yuya Saito, Ai Yoshimi, Hiroko Ogata-Kawata, Hiromi Sakamoto, Motohiro Kato, Junya Fujimura, Moeko Hino, Akitoshi Kinoshita, Harumi Kakuda, Hidemitsu Kurosawa, Keisuke Kato, Ryosuke Kajiwara, Koichi Moriwaki, Tsuyoshi Morimoto, Kozue Nakamura, Yasushi Noguchi, Tomoo Osumi, Kazuo Sakashita, Junko Takita, Yuki Yuza, Koich Matsuda, Teruhiko Yoshida, Kenji Matsumoto, Kenichiro Hata, Michiaki Kubo, Yoichi Matsubara, Takashi Fukushima, Katsuyoshi Koh, Atsushi Manabe, Akira Ohara, Nobutaka Kiyokawa

https://doi.org/10.3324/haematol.2016.151035

Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis (530 Online Views)

Tobias Herold, Stephanie Schneider, Klaus H. Metzeler, Martin Neumann, Luise Hartmann, Kathryn G. Roberts, Nikola P. Konstandin, Philipp A. Greif, Kathrin Bräundl, Bianka Ksienzyk, Natalia Huk, Irene Schneider, Evelyn Zellmeier, Vindi Jurinovic, Ulrich Mansmann, Wolfgang Hiddemann, Charles G. Mullighan, Stefan K. Bohlander, Karsten Spiekermann, Dieter Hoelzer, Monika Brüggemann, Claudia D. Baldus, Martin Dreyling, Nicola Gökbuget

https://doi.org/10.3324/haematol.2015.136366

Improving results of allogeneic hematopoietic cell transplantation for adults with acute lymphoblastic leukemia in first complete remission: an analysis from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (311 Online Views)

Sebastian Giebel, Myriam Labopin, Gerard Socié, Dietrich Beelen, Paul Browne, Liisa Volin, Slawomira Kyrcz-Krzemien, Ibrahim Yakoub-Agha, Mahmoud Aljurf, Depei Wu, Mauricette Michallet, Renate Arnold, Mohamad Mohty, Arnon Nagler

https://doi.org/10.3324/haematol.2016.145631

Non-Hodgkin Lymphoma

Mediastinal gray zone lymphoma: clinico-pathological characteristics and outcomes of 99 patients from the Lymphoma Study Association (944 Online Views)

Clémentine Sarkozy, Thierry Molina, Hervé Ghesquières, Anne-Sophie Michallet, Jehan Dupuis, Diane Damotte, Franck Morsschauser, Marie Parrens, Laurent Martin, Peggy Dartigues, Aspasia Stamatoullas, Pierre Hirsch, Bettina Fabiani, Krimo Bouabdallah, Maria Gomes da Silva, Marie Maerevoet, Camille Laurent, Bertrand Coiffier, Gilles Salles, Alexandra Traverse-Glehen

https://doi.org/10.3324/haematol.2016.152256

Plasma Cell Disorders

High-dose therapy and autologous stem cell transplantation in patients with POEMS syndrome: a retrospective study of the Plasma Cell Disorder sub-committee of the Chronic Malignancy Working Party of the European Society for Blood & Marrow Transplantation (335 Online Views)

Gordon Cook, Simona Iacobelli, Anja van Biezen, Dimitris Ziagkos, Veronique LeBlond, Julie Abraham, Grant McQuaker, Stefan Schoenland, Alessandro Rambaldi, Kazimierz Halaburda, Maria Rovira, Simona Sica, Jenny Byrne, Ramon Garcia Sanz, Arnon Nagler, Niels W.C.J. van de Donk, Marjatta Sinisalo, Mark Cook, Nicolaus Kröger, Theo De Witte, Curly Morris, Laurant Garderet

https://doi.org/10.3324/haematol.2016.148460

Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bortezomib and dexamethasone (249 Online Views)

Ana-Alicia López-Iglesias, Lorena González-Méndez, Laura San-Segundo, Ana B. Herrero, Susana Hernández-García, Montserrat Martín-Sánchez, Norma C. Gutiérrez, Teresa Paíno, Pablo Avilés, María-Victoria Mateos, Jesús F. San-Miguel, Mercedes Garayoa, Enrique M. Ocio

https://doi.org/10.3324/haematol.2016.146076

Cell Therapy & Immunotherapy

The increase of the global donor inventory is of limited benefit to patients of non-Northwestern European descent (129 Online Views)

Suzanna M. van Walraven, Anneke Brand, Jack N.A. Bakker, Martin B.A. Heemskerk, Suzan Nillesen, Marc B. Bierings, Laura B. Bungener, Bouke G. Hepkema, Arjan Lankester, Arnold van der Meer, Kees Sintnicolaas, Judith A.E. Somers, Eric Spierings, Marcel G.J. Tilanus, Christien E.M. Voorter, Jan J. Cornelissen, Machteld Oudshoorn

https://doi.org/10.3324/haematol.2016.145730

Sequential regimen of clofarabine, cytosine arabinoside and reduced-intensity conditioned transplantation for primary refractory acute myeloid leukemia (183 Online Views)

Mohamad Mohty, Florent Malard, Didier Blaise, Noel Milpied, Gérard Socié, Anne Huynh, Oumédaly Reman, Ibrahim Yakoub-Agha, Sabine Furst, Thierry Guillaume, Resa Tabrizi, Stéphane Vigouroux, Pierre Peterlin, Jean El-Cheikh, Philippe Moreau, Myriam Labopin, Patrice Chevallier

https://doi.org/10.3324/haematol.2016.150326

The immunophenotypic fingerprint of patients with primary antibody deficiencies is partially present in their asymptomatic first-degree relatives (117 Online Views)

Delfien J.A. Bogaert, Marieke De Bruyne, Veronique Debacker, Pauline Depuydt, Katleen De Preter, Carolien Bonroy, Jan Philippé, Victoria Bordon, Bart N. Lambrecht, Tessa Kerre, Andrea Cerutti, Karim Y. Vermaelen, Filomeen Haerynck, Melissa Dullaers

https://doi.org/10.3324/haematol.2016.149112

Treatments for hematologic malignancies in contrast to those for solid cancers are associated with reduced red cell alloimmunization (186 Online Views)

Dorothea Evers, Jaap Jan Zwaginga, Janneke Tijmensen, Rutger A. Middelburg, Masja de Haas, Karen M.K. de Vooght, Daan van de Kerkhof, Otto Visser, Nathalie C.V. Péquériaux, Francisca Hudig, Johanna G. van der Bom

https://doi.org/10.3324/haematol.2016.152074

Iron Metabolism & its Disorders

Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia (195 Online Views)

Chloé Latour, Myriam F. Wlodarczyk, Grace Jung, Aurélie Gineste, Nicolas Blanchard, Tomas Ganz, Marie-Paule Roth, Hélène Coppin, Léon Kautz

https://doi.org/10.3324/haematol.2016.150227

Bone Marrow Failure

A plasma microRNA signature as a biomarker for acquired aplastic anemia (249 Online Views)

Kohei Hosokawa, Sachiko Kajigaya, Xingmin Feng, Marie J. Desierto, Maria del Pilar Fernandez Ibanez, Olga Rios, Barbara Weinstein, Phillip Scheinberg, Danielle M. Townsley, Neal S. Young

https://doi.org/10.3324/haematol.2016.151076

Myeloproliferative Disorders

An accurate, simple prognostic model consisting of age, JAK2, CALR, and MPL mutation status for patients with primary myelofibrosis (508 Online Views)

Uri Rozovski, Srdan Verstovsek, Taghi Manshouri, Vilma Dembitz, Ksenija Bozinovic, Kate Newberry, Ying Zhang, Joseph E. Bove, Sherry Pierce, Hagop Kantarjian, Zeev Estrov

https://doi.org/10.3324/haematol.2016.149765

Associations between gender, disease features and symptom burden in patients with myeloproliferative neoplasms: an analysis by the MPN QOL International Working Group (374 Online Views)

Holly L. Geyer, Heidi Kosiorek, Amylou C. Dueck, Robyn Scherber, Stefanie Slot, Sonja Zweegman, Peter AW te Boekhorst, Zhenya Senyak, Harry C. Schouten, Federico Sackmann, Ana Kerguelen Fuentes, Dolores Hernández-Maraver, Heike L. Pahl, Martin Griesshammer, Frank Stegelmann, Konstanze Döhner, Thomas Lehmann, Karin Bonatz, Andreas Reiter, Francoise Boyer, Gabriel Etienne, Jean-Christophe Ianotto, Dana Ranta, Lydia Roy, Jean-Yves Cahn, Claire N. Harrison, Deepti Radia, Pablo Muxi, Norman Maldonado, Carlos Besses, Francisco Cervantes, Peter L. Johansson, Tiziano Barbui, Giovanni Barosi, Alessandro M. Vannucchi, Chiara Paoli, Francesco Passamonti, Bjorn Andreasson, Maria L Ferrari, Alessandro Rambaldi, Jan Samuelsson, Keith Cannon, Gunnar Birgegard, Zhijian Xiao, Zefeng Xu, Yue Zhang, Xiujuan Sun, Junqing Xu, Jean-Jacques Kiladjian, Peihong Zhang, Robert Peter Gale, Ruben A. Mesa

https://doi.org/10.3324/haematol.2016.149559

A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis (170 Online Views)

Vikas Gupta, Ruben A. Mesa, Michael W.N. Deininger, Candido E. Rivera, Shireen Sirhan, Carrie Baker Brachmann, Helen Collins, Jun Kawashima, Yan Xin, Srdan Verstovsek

https://doi.org/10.3324/haematol.2016.148924

Guidelines

Guideline for the diagnosis, treatment and response criteria for Bing-Neel syndrome (1242 Online Views)

Monique C. Minnema, Eva Kimby, Shirley D’Sa, Luc-Matthieu Fornecker, Stéphanie Poulain, Tom J. Snijders, Efstathios Kastritis, Stéphane Kremer, Aikaterini Fitsiori, Laurence Simon, Frédéric Davi, Michael Lunn, Jorge J. Castillo, Christopher J. Patterson, Magali Le Garff-Tavernier, Myrto Costopoulos, Véronique Leblond, Marie-José Kersten, Meletios A. Dimopoulos, Steven P. Treon

https://doi.org/10.3324/haematol.2016.147728

Online Only Articles

Letters to the Editor

APOL1, α-thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia (236 Online Views)

Santosh L. Saraf, Binal N. Shah, Xu Zhang, Jin Han, Bamidele O. Tayo, Taimur Abbasi, Adam Ostrower, Elizabeth Guzman, Robert E. Molokie, Michel Gowhari, Johara Hassan, Shivi Jain, Richard S. Cooper, Roberto F. Machado, James P. Lash, Victor R. Gordeuk

https://doi.org/10.3324/haematol.2016.154153

Genomic analysis of myeloproliferative neoplasms in chronic and acute phases (189 Online Views)

Frédéric Courtier, Nadine Carbuccia, Séverine Garnier, Arnaud Guille, José Adélaïde, Nathalie Cervera, Véronique Gelsi-Boyer, Marie-Joelle Mozziconacci, Jérôme Rey, Norbert Vey, Max Chaffanet, Daniel Birnbaum, Anne Murati

https://doi.org/10.3324/haematol.2016.152363

Absence of CALR mutations in JAK2-negative polycythemia (161 Online Views)

Aurélie Chauveau, Olivier Nibourel, Sylvie Tondeur, Damien Luque Paz, Olivier Mansier, Franciane Paul, Mathieu Wemeau, Claude Preudhomme, Eric Lippert, Valérie Ugo

https://doi.org/10.3324/haematol.2016.154799

CK2 inhibitor CX-4945 destabilizes NOTCH1 and synergizes with JQ1 against human T-acute lymphoblastic leukemic cells (200 Online Views)

Haiwei Lian, Dun Li, Yun Zhou, Esther Landesman-Bollag, Guanglan Zhang, Nicole M. Anderson, Kevin Charles Tang, Justine E. Roderick, Michelle A. Kelliher, David C. Seldin, Hui Fu, Hui Feng

https://doi.org/10.3324/haematol.2016.154013

Renal insufficiency is an independent prognostic factor in patients with chronic lymphocytic leukemia (101 Online Views)

Paolo Strati, Kari G. Chaffee, Sara J. Achenbach, Susan L. Slager, Nelson Leung, Timothy G. Call, Wei Ding, Sameer A. Parikh, Neil E Kay, Tait D. Shanafelt

https://doi.org/10.3324/haematol.2016.150706

Impaired pulmonary endothelial barrier function in sickle cell mice (77 Online Views)

Nagavedi S. Umapathy, Joyce Gonzales, Levi H. Makala, Hongyan Xu, Paul Biddinger, Betty S. Pace

https://doi.org/10.3324/haematol.2016.153098

Comment

Gene panel sequencing in idiopathic erythrocytosis (170 Online Views)

François Girodon, Fabrice Airaud, Céline Garrec, Stéphane Bézieau, Betty Gardie

https://doi.org/10.3324/haematol.2016.158337

Letters to the Editor

Myelodysplastic syndrome can propagate from the multipotent progenitor compartment (134 Online Views)

Kevin Rouault-Pierre, Alexander E. Smith, Syed A. Mian, Irene Pizzitola, Austin G. Kulasekararaj, Ghulam J. Mufti, Dominique Bonnet

https://doi.org/10.3324/haematol.2016.152520