Vol. 101 No. 12 (2016): December, 2016

Eltrombopag, a potent stimulator of megakaryopoiesis (1521 Online Views)

Hana Raslova, William Vainchenker, Isabelle Plo

https://doi.org/10.3324/haematol.2016.153668

The Hippo-p53 pathway in megakaryopoiesis (1082 Online Views)

Praveen K Suraneni, John D. Crispino

https://doi.org/10.3324/haematol.2016.156125

Ibrutinib in the real world patient: many lights and some shades (685 Online Views)

Paolo Ghia, Antonio Cuneo

https://doi.org/10.3324/haematol.2016.155986

The myeloma stem cell concept, revisited: from phenomenology to operational terms (4364 Online Views)

Hans Erik Johnsen, Martin Bøgsted, Alexander Schmitz, Julie Støve Bødker, Tarec Christoffer El-Galaly, Preben Johansen, Peter Valent, Niklas Zojer, Els Van Valckenborgh, Karin Vanderkerken, Mark van Duin, Pieter Sonneveld, Martin Perez-Andres, Alberto Orfao, Karen Dybkær

https://doi.org/10.3324/haematol.2015.138826

‘Trained immunity’: consequences for lymphoid malignancies (2622 Online Views)

Wendy B.C. Stevens, Mihai G. Netea, Arnon P. Kater, Walter J.F.M. van der Velden

https://doi.org/10.3324/haematol.2016.149252

Uncoupling of the Hippo and Rho pathways allows megakaryocytes to escape the tetraploid checkpoint (1633 Online Views)

Anita Roy, Larissa Lordier, Catherine Pioche-Durieu, Sylvie Souquere, Lydia Roy, Philippe Rameau, Valérie Lapierre, Eric Le Cam, Isabelle Plo, Najet Debili, Hana Raslova, William Vainchenker

https://doi.org/10.3324/haematol.2016.149914

Revealing eltrombopag’s promotion of human megakaryopoiesis through AKT/ERK-dependent pathway activation (2051 Online Views)

Christian A. Di Buduo, Manuela Currao, Alessandro Pecci, David L. Kaplan, Carlo L. Balduini, Alessandra Balduini

https://doi.org/10.3324/haematol.2016.146746

Unexpected macrophage-independent dyserythropoiesis in Gaucher disease (903 Online Views)

Nelly Reihani, Jean-Benoit Arlet, Michael Dussiot, Thierry Billette de Villemeur, Nadia Belmatoug, Christian Rose, Yves Colin-Aronovicz, Olivier Hermine, Caroline Le Van Kim, Melanie Franco

https://doi.org/10.3324/haematol.2016.147546

Wnt5a is a key target for the pro-osteogenic effects of iron chelation on osteoblast progenitors (1904 Online Views)

Ulrike Baschant, Martina Rauner, Ekaterina Balaian, Heike Weidner, Antonella Roetto, Uwe Platzbecker, Lorenz C. Hofbauer

https://doi.org/10.3324/haematol.2016.144808

Response to treatment with azacitidine in children with advanced myelodysplastic syndrome prior to hematopoietic stem cell transplantation (2002 Online Views)

Nicolas Waespe, Machiel Van Den Akker, Robert J. Klaassen, Lani Lieberman, Meredith S. Irwin, Salah S. Ali, Mohamed Abdelhaleem, Bozana Zlateska, Mira Liebman, Michaela Cada, Tal Schechter, Yigal Dror

https://doi.org/10.3324/haematol.2016.145821

Chromosome abnormalities at onset of complete remission are associated with worse outcome in patients with acute myeloid leukemia and an abnormal karyotype at diagnosis: CALGB 8461 (Alliance) (957 Online Views)

Christian Niederwieser, Deedra Nicolet, Andrew J. Carroll, Jonathan E. Kolitz, Bayard L. Powell, Jessica Kohlschmidt, Richard M. Stone, John C. Byrd, Krzysztof Mrózek, Clara D. Bloomfield

https://doi.org/10.3324/haematol.2016.149542

International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia (3495 Online Views)

Nicola Gökbuget, Hervè Dombret, Jose-Maria Ribera, Adele K. Fielding, Anjali Advani, Renato Bassan, Victoria Chia, Michael Doubek, Sebastian Giebel, Dieter Hoelzer, Norbert Ifrah, Aaron Katz, Michael Kelsh, Giovanni Martinelli, Mireia Morgades, Susan O’Brien, Jacob M. Rowe, Julia Stieglmaier, Martha Wadleigh, Hagop Kantarjian

https://doi.org/10.3324/haematol.2016.144311

CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia (1788 Online Views)

Benjamin Neveu, Jean-François Spinella, Chantal Richer, Karine Lagacé, Pauline Cassart, Mathieu Lajoie, Silvana Jananji, Simon Drouin, Jasmine Healy, Gilles R.X. Hickson, Daniel Sinnett

https://doi.org/10.3324/haematol.2016.149740

A sequential approach with imatinib, chemotherapy and transplant for adult Ph+ acute lymphoblastic leukemia: final results of the GIMEMA LAL 0904 study (2235 Online Views)

Sabina Chiaretti, Antonella Vitale, Marco Vignetti, Alfonso Piciocchi, Paola Fazi, Loredana Elia, Brunangelo Falini, Francesca Ronco, Felicetto Ferrara, Paolo De Fabritiis, Mario Luppi, Giorgio La Nasa, Alessandra Tedeschi, Catello Califano, Renato Fanin, Fausto Dore, Franco Mandelli, Giovanna Meloni, Robin Foà

https://doi.org/10.3324/haematol.2016.144535

SLP76 integrates into the B-cell receptor signaling cascade in chronic lymphocytic leukemia cells and is associated with an aggressive disease course (1039 Online Views)

Nili Dezorella, Ben-Zion Katz, Mika Shapiro, Aaron Polliack, Chava Perry, Yair Herishanu

https://doi.org/10.3324/haematol.2015.139154

Ibrutinib for relapsed/refractory chronic lymphocytic leukemia: a UK and Ireland analysis of outcomes in 315 patients (3212 Online Views)

UK CLL Forum

https://doi.org/10.3324/haematol.2016.147900

Real-world results of ibrutinib in patients with relapsed or refractory chronic lymphocytic leukemia: data from 95 consecutive patients treated in a compassionate use program. A study from the Swedish Chronic Lymphocytic Leukemia Group (1808 Online Views)

Maria Winqvist, Anna Asklid, PO Andersson, Karin Karlsson, Claes Karlsson, Birgitta Lauri, Jeanette Lundin, Mattias Mattsson, Stefan Norin, Anna Sandstedt, Lotta Hansson, Anders Österborg

https://doi.org/10.3324/haematol.2016.144576

Non-Hodgkin lymphoma and pre-existing conditions: spectrum, clinical characteristics and outcome in 213 children and adolescents (2082 Online Views)

Andishe Attarbaschi, Elisa Carraro, Oussama Abla, Shlomit Barzilai-Birenboim, Simon Bomken, Laurence Brugieres, Eva Bubanska, Birgit Burkhardt, Alan K.S. Chiang, Monika Csoka, Alina Fedorova, Janez Jazbec, Edita Kabickova, Zdenka Krenova, Jelena Lazic, Jan Loeffen, Georg Mann, Felix Niggli, Natalia Miakova, Tomoo Osumi, Leila Ronceray, Anne Uyttebroeck, Denise Williams, Wilhelm Woessmann, Grazyna Wrobel, Marta Pillon

https://doi.org/10.3324/haematol.2016.147116

Comparison of graft-versus-host disease-free, relapse-free survival according to a variety of graft sources: antithymocyte globulin and single cord blood provide favorable outcomes in some subgroups (1670 Online Views)

Yoshihiro Inamoto, Fumihiko Kimura, Junya Kanda, Junichi Sugita, Kazuhiro Ikegame, Hideki Nakasone, Yasuhito Nannya, Naoyuki Uchida, Takahiro Fukuda, Kosuke Yoshioka, Yukiyasu Ozawa, Ichiro Kawano, Yoshiko Atsuta, Koji Kato, Tatsuo Ichinohe, Masami Inoue, Takanori Teshima

https://doi.org/10.3324/haematol.2016.149427

Metabolic syndrome in long-term survivors of childhood acute leukemia treated without hematopoietic stem cell transplantation: an L.E.A. study (1378 Online Views)

Paul Saultier, Pascal Auquier, Yves Bertrand, Camille Vercasson, Claire Oudin, Audrey Contet, Dominique Plantaz, Marilyne Poirée, Stéphane Ducassou, Justyna Kanold, Marie-Dominique Tabone, Jean-Hugues Dalle, Patrick Lutz, Virginie Gandemer, Nicolas Sirvent, Sandrine Thouvenin, Julie Berbis, Hervé Chambost, André Baruchel, Guy Leverger, Gérard Michel

https://doi.org/10.3324/haematol.2016.148908

Nocturnal enuresis and K+ transport in red blood cells from patients with sickle cell anemia (625 Online Views)

Sanjay Tewari, David C. Rees, Anke Hannemann, Oluwabukola T. Gbotosho, Halima W. M. Al Balushi, John S. Gibson

https://doi.org/10.3324/haematol.2016.149500

D-dimer measured at first venous thromboembolism is associated with future risk of cancer (1690 Online Views)

Olga V. Gran, Sigrid K. Brækkan, Benedikte Paulsen, Hanne Skille, John-Bjarne Hansen

https://doi.org/10.3324/haematol.2016.151712

Remissions after long-term use of romiplostim for immune thrombocytopenia (781 Online Views)

Ariela L. Marshall, Roberta Scarpone, Melanie De Greef, Robert Bird, David J. Kuter

https://doi.org/10.3324/haematol.2016.151886

Lack of splice factor and cohesin complex mutations in pediatric myelodysplastic syndrome (606 Online Views)

Julia C. Obenauer, François G. Kavelaars, Mathijs A. Sanders, Remco M. Hoogenboezem, Andrica C. H. de Vries, Paulina M. H. van Strien, Valerie de Haas, Franco Locatelli, Henrik Hasle, Peter J. M. Valk, Ivo P. Touw, Marry M. van den Heuvel-Eibrink

https://doi.org/10.3324/haematol.2016.151753

The impact of anemia on overall survival in patients with myelofibrosis treated with ruxolitinib in the COMFORT studies (1647 Online Views)

Vikas Gupta, Claire Harrison, Elizabeth O. Hexner, Haifa Kathrin Al-Ali, Lynda Foltz, Michael Montgomery, William Sun, Prashanth Gopalakrishna, Hagop Kantarjian, Srdan Verstovsek

https://doi.org/10.3324/haematol.2016.151449

Peripheral neuropathy associated with subcutaneous or intravenous bortezomib in patients with newly diagnosed myeloma treated within the GMMG MM5 phase III trial (902 Online Views)

Maximilian Merz, Hans Salwender, Mathias Haenel, Elias K. Mai, Uta Bertsch, Christina Kunz, Thomas Hielscher, Igor W. Blau, Christof Scheid, Dirk Hose, Anja Seckinger, Anna Jauch, Jens Hillengass, Marc S. Raab, Baerbel Schurich, Markus Munder, Peter Brossart, Christian Gerecke, Hans-Walter Lindemann, Matthias Zeis, Katja Weisel, Jan Duerig, Hartmut Goldschmidt

https://doi.org/10.3324/haematol.2016.151266