June, 2018
No. 103 (6)

Editorials

Perspective Articles

Review Articles

Articles

Acute Lymphoblastic Leukemia

Leukemia reconstitution in vivo is driven by cells in early cell cycle and low metabolic state (408 Online Views)

Luca Trentin, Manon Queudeville, Sarah Mirjam Eckhoff, Nabiul Hasan, Vera Münch, Elena Boldrin, Felix Seyfried, Stefanie Enzenmüller, Klaus-Michael Debatin, Lüder Hinrich Meyer

https://doi.org/10.3324/haematol.2017.167502

Non-Hodgkin Lymphoma

A distinct subtype of Epstein-Barr virus-positive T/NK-cell lymphoproliferative disorder: adult patients with chronic active Epstein-Barr virus infection-like features (719 Online Views)

Keisuke Kawamoto, Hiroaki Miyoshi, Takaharu Suzuki, Yasuji Kozai, Koji Kato, Masaharu Miyahara, Toshiaki Yujiri, Ilseung Choi, Katsumichi Fujimaki, Tsuyoshi Muta, Masaaki Kume, Sayaka Moriguchi, Shinobu Tamura, Takeharu Kato, Hiroyuki Tagawa, Junya Makiyama, Yuji Kanisawa, Yuya Sasaki, Daisuke Kurita, Kyohei Yamada, Joji Shimono, Hirohito Sone, Jun Takizawa, Masao Seto, Hiroshi Kimura, Koichi Ohshima

https://doi.org/10.3324/haematol.2017.174177

Highly sensitive MYD88L265P mutation detection by droplet digital polymerase chain reaction in Waldenström macroglobulinemia (512 Online Views)

Daniela Drandi, Elisa Genuardi, Irene Dogliotti, Martina Ferrante, Cristina Jiménez, Francesca Guerrini, Mariella Lo Schirico, Barbara Mantoan, Vittorio Muccio, Giuseppe Lia, Gian Maria Zaccaria, Paola Omedè, Roberto Passera, Lorella Orsucci, Giulia Benevolo, Federica Cavallo, Sara Galimberti, Ramón García Sanz, Mario Boccadoro, Marco Ladetto, Simone Ferrero

https://doi.org/10.3324/haematol.2017.186528

Chronic Lymphocytic Leukemia

DNA polymerase ν gene expression influences fludarabine resistance in chronic lymphocytic leukemia independently of p53 status (248 Online Views)

Srdana Grgurevic, Patricia Montilla-Perez, Alice Bradbury, Julia Gilhodes, Sophie Queille, Sandrine Pelofy, Aurélien Bancaud, Thomas Filleron, Loïc Ysebaert, Christian Récher, Guy Laurent, Jean-Jacques Fournié, Christophe Cazaux, Anne Quillet-Mary, Jean-Sébastien Hoffmann

https://doi.org/10.3324/haematol.2017.174243

Plasma Cell Disorders

Treatment to suppression of focal lesions on positron emission tomography-computed tomography is a therapeutic goal in newly diagnosed multiple myeloma (214 Online Views)

Faith E. Davies, Adam Rosenthal, Leo Rasche, Nathan M. Petty, James E. McDonald, James A. Ntambi, Doug M. Steward, Susan B. Panozzo, Frits van Rhee, Maurizio Zangari, Carolina D. Schinke, Sharmilan Thanendrarajan, Brian Walker, Niels Weinhold, Bart Barlogie, Antje Hoering, Gareth J. Morgan

https://doi.org/10.3324/haematol.2017.177139

Stem Cell Transplantation

A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support (606 Online Views)

Amar Desai, Yongyou Zhang, Youngsoo Park, Dawn M. Dawson, Gretchen A. Larusch, Lakshmi Kasturi, David Wald, Joseph M. Ready, Stanton L. Gerson, Sanford D. Markowitz

https://doi.org/10.3324/haematol.2017.178376

Cell Therapy & Immunotherapy

Targeting the anion exchanger 2 with specific peptides as a new therapeutic approach in B lymphoid neoplasms (170 Online Views)

Jon Celay, Teresa Lozano, Axel R. Concepcion, Elena Beltrán, Francesc Rudilla, María José García-Barchino, Eloy F. Robles, Obdulia Rabal, Irene de Miguel, Carlos Panizo, Noelia Casares, Julen Oyarzabal, Jesús Prieto, Juan F. Medina, Juan José Lasarte, José Ángel Martínez-Climent

https://doi.org/10.3324/haematol.2017.175687

Coagulation & its Disorders

Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity (259 Online Views)

Kondababu Kurakula, Duco S. Koenis, Mark A. Herzik, Yanyun Liu, John W. Craft, Pieter B. van Loenen, Mariska Vos, M. Khang Tran, Henri H. Versteeg, Marie-José T.H. Goumans, Wolfram Ruf, Carlie J.M. de Vries, Mehmet Şen

https://doi.org/10.3324/haematol.2017.183087

Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ (221 Online Views)

Johana Hrdinová, Fabian C. Verbij, Paul H.P. Kaijen, Robin B. Hartholt, Floris van Alphen, Neubury Lardy, Anja ten Brinke, Karen Vanhoorelbeke, Pooja J. Hindocha, Anne S. De Groot, Alexander B. Meijer, Jan Voorberg, Ivan Peyron

https://doi.org/10.3324/haematol.2017.179119

Hematopoiesis

BET-inhibition by JQ1 promotes proliferation and self-renewal capacity of hematopoietic stem cells (644 Online Views)

Mark Wroblewski, Marina Scheller-Wendorff, Florian Udonta, Raimund Bauer, Jara Schlichting, Lin Zhao, Isabel Ben Batalla, Victoria Gensch, Sarina Päsler, Lei Wu, Marek Wanior, Hanna Taipaleenmäki, Simona Bolamperti, Zeynab Najafova, Klaus Pantel, Carsten Bokemeyer, Jun Qi, Eric Hesse, Stefan Knapp, Steven Johnsen, Sonja Loges

https://doi.org/10.3324/haematol.2017.181354

Red Cell Biology & its Disorders

Recurring mutations in RPL15 are linked to hydrops fetalis and treatment independence in Diamond-Blackfan anemia (511 Online Views)

Marcin W. Wlodarski, Lydie Da Costa, Marie-Françoise O’Donohue, Marc Gastou, Narjesse Karboul, Nathalie Montel-Lehry, Ina Hainmann, Dominika Danda, Amina Szvetnik, Victor Pastor, Nahuel Paolini, Franca M. di Summa, Hannah Tamary, Abed Abu Quider, Anna Aspesi, Riekelt H. Houtkooper, Thierry Leblanc, Charlotte M. Niemeyer, Pierre-Emmanuel Gleizes, Alyson W. MacInnes

https://doi.org/10.3324/haematol.2017.177980

Myelodysplastic Syndromes

Cytokines increase engraftment of human acute myeloid leukemia cells in immunocompromised mice but not engraftment of human myelodysplastic syndrome cells (471 Online Views)

Maria Krevvata, Xiaochuan Shan, Chenghui Zhou, Cedric Dos Santos, Georges Habineza Ndikuyeze, Anthony Secreto, Joshua Glover, Winifred Trotman, Gisela Brake-Silla, Selene Nunez-Cruz, Gerald Wertheim, Hyun-Jeong Ra, Elizabeth Griffiths, Charalampos Papachristou, Gwenn Danet-Desnoyers, Martin Carroll

https://doi.org/10.3324/haematol.2017.183202

Myeloproliferative Neoplasms

Impact of hydroxycarbamide and interferon-α on red cell adhesion and membrane protein expression in polycythemia vera (281 Online Views)

Mégane Brusson, Maria De Grandis, Sylvie Cochet, Sylvain Bigot, Mickaël Marin, Marjorie Leduc, François Guillonneau, Patrick Mayeux, Thierry Peyrard, Christine Chomienne, Caroline Le Van Kim, Bruno Cassinat, Jean-Jacques Kiladjian, Wassim El Nemer

https://doi.org/10.3324/haematol.2017.182303

Acute Myeloid Leukemia

A novel regimen for relapsed/refractory adult acute myeloid leukemia using a KMT2A partial tandem duplication targeted therapy: results of phase 1 study NCI 8485 (401 Online Views)

Alice S. Mims, Anjali Mishra, Shelley Orwick, James Blachly, Rebecca B. Klisovic, Ramiro Garzon, Alison R. Walker, Steven M. Devine, Katherine J. Walsh, Sumithira Vasu, Susan Whitman, Guido Marcucci, Daniel Jones, Nyla A. Heerema, Gerard Lozanski, Michael A. Caligiuri, Clara D. Bloomfield, John C. Byrd, Richard Piekarz, Michael R. Grever, William Blum

https://doi.org/10.3324/haematol.2017.186890

Dexamethasone in hyperleukocytic acute myeloid leukemia (1915 Online Views)

Sarah Bertoli, Muriel Picard, Emilie Bérard, Emmanuel Griessinger, Clément Larrue, Pierre Luc Mouchel, François Vergez, Suzanne Tavitian, Edwige Yon, Jean Ruiz, Eric Delabesse, Isabelle Luquet, Laetitia Karine Linares, Estelle Saland, Martin Carroll, Gwenn Danet-Desnoyers, Audrey Sarry, Françoise Huguet, Jean Emmanuel Sarry, Christian Récher

https://doi.org/10.3324/haematol.2017.184267

Acute Lymphoblastic Leukemia

Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes (319 Online Views)

Stéphanie Gon, Marie Loosveld, Thomas Crouzet, Delphine Potier, Mélanie Bonnet, Stéphanie O. Morin, Gérard Michel, Norbert Vey, Jacques A. Nunès, Bernard Malissen, Romain Roncagalli, Bertrand Nadel, Dominique Payet-Bornet

https://doi.org/10.3324/haematol.2018.188359

Online Only Articles

Memory CD8+ T cells support the maintenance of hematopoietic stem cells in the bone marrow (280 Online Views)

Sulima Geerman, Giso Brasser, Sudeep Bhushal, Fiamma Salerno, Natasja A. Kragten, Mark Hoogenboezem, Gerald de Haan, Monika C. Wolkers, María Fernanda Pascutti, Martijn A. Nolte

https://doi.org/10.3324/haematol.2017.169516

Outcomes of a large cohort of individuals with clinically ascertained high-count monoclonal B-cell lymphocytosis (158 Online Views)

Sameer A. Parikh, Kari G. Chaffee, Melissa C. Larson, Paul J. Hampel, Timothy G. Call, Wei Ding, Saad S. Kenderian, Jose F. Leis, Asher A. Chanan-Khan, Michael J. Conte, Deborah Bowen, Susan M. Schwager, Susan L. Slager, Curtis A. Hanson, Neil E. Kay, Tait D. Shanafelt

https://doi.org/10.3324/haematol.2017.183194

Liquid biopsy for the identification of intravascular large B-cell lymphoma (393 Online Views)

Yasuhito Suehara, Mamiko Sakata-Yanagimoto, Keiichiro Hattori, Toru Nanmoku, Takayoshi Itoh, Daisuke Kaji, Go Yamamoto, Yoshiaki Abe, Kentaro Narita, Masami Takeuchi, Kosei Matsue, Taiki Sato, Masayuki Noguchi, Naoko Baba, Tatsuhiro Sakamoto, Manabu Kusakabe, Naoki Kurita, Takayasu Kato, Yasuhisa Yokoyama, Hidekazu Nishikii, Naoshi Obara, Yuichi Hasegawa, Shigeru Chiba

https://doi.org/10.3324/haematol.2017.178830

Circulating tumor DNA as a liquid biopsy in plasma cell dyscrasias (263 Online Views)

Bernhard Gerber, Martina Manzoni, Valeria Spina, Alessio Bruscaggin, Marta Lionetti, Sonia Fabris, Marzia Barbieri, Gabriella Ciceri, Alessandra Pompa, Gabriela Forestieri, Erika Lerch, Paolo Servida, Francesco Bertoni, Emanuele Zucca, Michele Ghielmini, Agostino Cortelezzi, Franco Cavalli, Georg Stussi, Luca Baldini, Davide Rossi, Antonino Neri

https://doi.org/10.3324/haematol.2017.184358

Survival adjusting for crossover: phase 3 study of ibrutinib vs. chlorambucil in older patients with untreated chronic lymphocytic leukemia/small lymphocytic lymphoma (394 Online Views)

Steven Coutre, Alessandra Tedeschi, Tadeusz Robak, Paul M. Barr, Carolyn Owen, Osnat Bairey, Jan Burger, Cathy Zhou, Lori Styles, Danelle F. James, Thomas J. Kipps

https://doi.org/10.3324/haematol.2017.175380

Non-myeloablative allogeneic hematopoietic cell transplantation for relapsed or refractory Waldenström macroglobulinemia: evidence for a graft-versus-lymphoma effect (122 Online Views)

Enrico Maffini, Larry D. Anderson, Brenda M. Sandmaier, Damian J. Green, Barry E. Storer, Dietger Niederwieser, Richard T. Maziarz, David G. Maloney, Rainer Storb

https://doi.org/10.3324/haematol.2017.184176

The contribution of platelet glycoprotein receptors to inflammatory bleeding prevention is stimulus and organ dependent (261 Online Views)

Julie Rayes, Soumaya Jadoui, Siân Lax, Angèle Gros, Surasak Wichaiyo, Véronique Ollivier, Cécile V. Denis, Jerry Ware, Bernhard Nieswandt, Martine Jandrot-Perrus, Steve P. Watson, Benoît Ho-Tin-Noé

https://doi.org/10.3324/haematol.2017.182162

Long-term management of leukocyte adhesion deficiency type III without hematopoietic stem cell transplantation (474 Online Views)

Paul Saultier, Sarah Szepetowski, Matthias Canault, Céline Falaise, Marjorie Poggi, Pierre Suchon, Vincent Barlogis, Gérard Michel, Stéphane Loyau, Martine Jandrot-Perrus, Jean-Claude Bordet, Marie-Christine Alessi, Hervé Chambost

https://doi.org/10.3324/haematol.2017.186304

Down syndrome-like acute megakaryoblastic leukemia in a patient with Cornelia de Lange syndrome (184 Online Views)

Yoann Vial, Julie Lachenaud, Alain Verloes, Marianne Besnard, Odile Fenneteau, Elodie Lainey, Alice Marceau-Renaut, Claude Preudhomme, André Baruchel, Hélène Cavé, Séverine Drunat

https://doi.org/10.3324/haematol.2017.178590