May, 2018
No. 103 (5)

Editorials

Perspective Articles

Osteoprotective medication in the era of novel agents: a European perspective on values, risks and future solutions (280 Online Views)

Monika Engelhardt, Georg W. Herget, Giulia Graziani, Gabriele Ihorst, Heike Reinhardt, Stefanie Ajayi, Stefan Knop, Ralph Wasch

https://doi.org/10.3324/haematol.2018.188516

Articles

Bone Marrow Failure

Red Cell Biology & its Disorders

Safety and efficacy of plerixafor dose escalation for the mobilization of CD34+ hematopoietic progenitor cells in patients with sickle cell disease: interim results (780 Online Views)

Farid Boulad, Tsiporah Shore, Koen van Besien, Caterina Minniti, Mihaela Barbu-Stevanovic, Sylvie Wiener Fedus, Fabiana Perna, June Greenberg, Danielle Guarneri, Vijay Nandi, Audrey Mauguen, Karina Yazdanbakhsh, Michel Sadelain, Patricia A. Shi

https://doi.org/10.3324/haematol.2017.187047

Plerixafor enables safe, rapid, efficient mobilization of hematopoietic stem cells in sickle cell disease patients after exchange transfusion (987 Online Views)

Chantal Lagresle-Peyrou, François Lefrère, Elisa Magrin, Jean-Antoine Ribeil, Oriana Romano, Leslie Weber, Alessandra Magnani, Hanem Sadek, Clémence Plantier, Aurélie Gabrion, Brigitte Ternaux, Tristan Félix, Chloé Couzin, Aurélie Stanislas, Jean-Marc Tréluyer, Lionel Lamhaut, Laure Joseph, Marianne Delville, Annarita Miccio, Isabelle André-Schmutz, Marina Cavazzana

https://doi.org/10.3324/haematol.2017.184788

RON kinase inhibition reduces renal endothelial injury in sickle cell disease mice (406 Online Views)

Alfia Khaibullina, Elena A. Adjei, Nowah Afangbedji, Andrey Ivanov, Namita Kumari, Luis E.F. Almeida, Zenaide M.N. Quezado, Sergei Nekhai, Marina Jerebtsova

https://doi.org/10.3324/haematol.2017.180992

Myeloproliferative Disorders

The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis (723 Online Views)

Mathias Schneeweiss, Barbara Peter, Siham Bibi, Gregor Eisenwort, Dubravka Smiljkovic, Katharina Blatt, Mohamad Jawhar, Daniela Berger, Gabriele Stefanzl, Susanne Herndlhofer, Georg Greiner, Gregor Hoermann, Emir Hadzijusufovic, Karoline V. Gleixner, Peter Bettelheim, Klaus Geissler, Wolfgang R. Sperr, Andreas Reiter, Michel Arock, Peter Valent

https://doi.org/10.3324/haematol.2017.179895

Acute Myeloid Leukemia

Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival (541 Online Views)

Steven M. Kornblau, Peter P. Ruvolo, Rui-Yu Wang, V. Lokesh Battula, Elizabeth J. Shpall, Vivian R. Ruvolo, Teresa McQueen, YiHua Qui, Zhihong Zeng, Sherry Pierce, Rodrigo Jacamo, Suk-Young Yoo, Phuong M. Le, Jeffrey Sun, Numsen Hail, Marina Konopleva, Michael Andreeff

https://doi.org/10.3324/haematol.2017.172429

Clinical relevance of IDH1/2 mutant allele burden during follow-up in acute myeloid leukemia. A study by the French ALFA group (515 Online Views)

Yann Ferret, Nicolas Boissel, Nathalie Helevaut, Jordan Madic, Olivier Nibourel, Alice Marceau-Renaut, Maxime Bucci, Sandrine Geffroy, Karine Celli-Lebras, Sylvie Castaigne, Xavier Thomas, Christine Terré, Hervé Dombret, Claude Preudhomme, Aline Renneville

https://doi.org/10.3324/haematol.2017.183525

Acute Lymphoblastic Leukemia

MSH6 haploinsufficiency at relapse contributes to the development of thiopurine resistance in pediatric B-lymphoblastic leukemia (400 Online Views)

Nikki A. Evensen, P. Pallavi Madhusoodhan, Julia Meyer, Jason Saliba, Ashfiyah Chowdhury, David J. Araten, Jacob Nersting, Teena Bhatla, Tiffaney L. Vincent, David Teachey, Stephen P. Hunger, Jun Yang, Kjeld Schmiegelow, William L. Carroll

https://doi.org/10.3324/haematol.2017.176362

Hodgkin Lymphoma

A phase II study of the oral JAK1/JAK2 inhibitor ruxolitinib in advanced relapsed/refractory Hodgkin lymphoma (455 Online Views)

Eric Van Den Neste, Marc André, Thomas Gastinne, Aspasia Stamatoullas, Corinne Haioun, Amine Belhabri, Oumedaly Reman, Olivier Casasnovas, Hervé Ghesquieres, Gregor Verhoef, Marie-José Claessen, Hélène A. Poirel, Marie-Christine Copin, Romain Dubois, Peter Vandenberghe, Ioanna-Andrea Stoian, Anne S. Cottereau, Sarah Bailly, Laurent Knoops, Franck Morschhauser

https://doi.org/10.3324/haematol.2017.180554

Non-Hodgkin Lymphoma

A B-cell receptor-related gene signature predicts survival in mantle cell lymphoma: results from the Fondazione Italiana Linfomi MCL-0208 trial (430 Online Views)

Riccardo Bomben, Simone Ferrero, Tiziana D’Agaro, Michele Dal Bo, Alessandro Re, Andrea Evangelista, Angelo Michele Carella, Alberto Zamò, Umberto Vitolo, Paola Omedè, Chiara Rusconi, Luca Arcaini, Luigi Rigacci, Stefano Luminari, Andrea Piccin, Delong Liu, Adrian Wiestner, Gianluca Gaidano, Sergio Cortelazzo, Marco Ladetto, Valter Gattei

https://doi.org/10.3324/haematol.2017.184325

Incidence and risk factors for relapses in HIV-associated non-Hodgkin lymphoma as observed in the German HIV-related lymphoma cohort study (634 Online Views)

Philipp Schommers, Daniel Gillor, Marcus Hentrich, Christoph Wyen, Timo Wolf, Mark Oette, Alexander Zoufaly, Jan-Christian Wasmuth, Johannes R. Bogner, Markus Müller, Stefan Esser, Alisa Schleicher, Björn Jensen, Albrecht Stoehr, Georg Behrens, Alexander Schultze, Jan Siehl, Jan Thoden, Ninon Taylor, Christian Hoffmann

https://doi.org/10.3324/haematol.2017.180893

Chronic Lymphocytic Leukemia

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations (473 Online Views)

Andreas Agathangelidis, Viktor Ljungström, Lydia Scarfò, Claudia Fazi, Maria Gounari, Tatjana Pandzic, Lesley-Ann Sutton, Kostas Stamatopoulos, Giovanni Tonon, Richard Rosenquist, Paolo Ghia

https://doi.org/10.3324/haematol.2017.177212

Toxicities and outcomes of 616 ibrutinib-treated patients in the United States: a real-world analysis (1900 Online Views)

Anthony R. Mato, Chadhi Nabhan, Meghan C. Thompson, Nicole Lamanna, Danielle M. Brander, Brian Hill, Christina Howlett, Alan Skarbnik, Bruce D. Cheson, Clive Zent, Jeffrey Pu, Pavel Kiselev, Andre Goy, David Claxton, Krista Isaac, Kaitlin H. Kennard, Colleen Timlin, Daniel Landsburg, Allison Winter, Sunita D. Nasta, Spencer H. Bachow, Stephen J. Schuster, Colleen Dorsey, Jakub Svoboda, Paul Barr, Chaitra S. Ujjani

https://doi.org/10.3324/haematol.2017.182907

Plasma Cell Disorders

A novel nano-immunoassay method for quantification of proteins from CD138-purified myeloma cells: biological and clinical utility (787 Online Views)

Irena Misiewicz-Krzeminska, Luis Antonio Corchete, Elizabeta A. Rojas, Joaquín Martínez-López, Ramón García-Sanz, Albert Oriol, Joan Bladé, Juan-José Lahuerta, Jesús San Miguel, María-Victoria Mateos, Norma C. Gutiérrez

https://doi.org/10.3324/haematol.2017.181628

Impact of extramedullary disease in patients with newly diagnosed multiple myeloma undergoing autologous stem cell transplantation: a study from the Chronic Malignancies Working Party of the EBMT (472 Online Views)

Nico Gagelmann, Diderik-Jan Eikema, Simona Iacobelli, Linda Koster, Hareth Nahi, Anne-Marie Stoppa, Tamás Masszi, Denis Caillot, Stig Lenhoff, Miklos Udvardy, Charles Crawley, William Arcese, Clara Mariette, Ann Hunter, Xavier Leleu, Martin Schipperus, Michel Delforge, Pietro Pioltelli, John A. Snowden, Maija Itälä-Remes, Maurizio Musso, Anja van Biezen, Laurent Garderet, Nicolaus Kröger

https://doi.org/10.3324/haematol.2017.178434

Hemostasis

Immobilized fibrinogen activates human platelets through glycoprotein VI (918 Online Views)

Pierre H Mangin, Marie-Blanche Onselaer, Nicolas Receveur, Nicolas Le Lay, Alexander T Hardy, Clare Wilson, Ximena Sanchez, Stéphane Loyau, Arnaud Dupuis, Amir K Babar, Jeanette LC Miller, Helen Philippou, Craig E Hughes, Andrew B Herr, Robert AS Ariëns, Diego Mezzano, Martine Jandrot-Perrus, Christian Gachet, Steve P. Watson

https://doi.org/10.3324/haematol.2017.182972

Coagulation & its Disorders

Circulating microRNAs as biomarkers of disease and typification of the atherothrombotic status in antiphospholipid syndrome (426 Online Views)

Carlos Pérez-Sánchez, Iván Arias-de la Rosa, María Ángeles Aguirre, María Luque-Tévar, Patricia Ruiz-Limón, Nuria Barbarroja, Yolanda Jiménez-Gómez, María Carmen Ábalos-Aguilera, Eduardo Collantes-Estévez, Pedro Segui, Francisco Velasco, María Teresa Herranz, Jesús Lozano-Herrero, María Julia Hernandez-Vidal, Constantino Martínez, Rocío González-Conejero, Massimo Radin, Savino Sciascia, Irene Cecchi, María José Cuadrado, Chary López-Pedrera

https://doi.org/10.3324/haematol.2017.184416

Online Only Articles

Iron overload in transfusion-dependent survivors of hemoglobin Bart’s hydrops fetalis (195 Online Views)

Ali Amid, Shiyi Chen, Uma Athale, Karen Charpentier, Manuela Merelles-Pulcini, Isaac Odame, Melanie Kirby-Allen

https://doi.org/10.3324/haematol.2017.178368

Clonal evolution in the transition from cutaneous disease to acute leukemia suggested by liquid biopsy in blastic plasmacytoid dendritic cell neoplasm (323 Online Views)

Eleni Ladikou, Barbara Ottolini, Nadia Nawaz, Rebecca L. Allchin, Daniel Payne, Hebah Ali, Teresa Marafioti, Jacqui Shaw, Matthew J. Ahearne, Simon D. Wagner

https://doi.org/10.3324/haematol.2017.171876

Heterozygous carriers of germline c.657_661del5 founder mutation in NBN gene are at risk of central nervous system relapse of B-cell precursor acute lymphoblastic leukemia (380 Online Views)

Bartłomiej Tomasik, Agata Pastorczak, Wojciech Fendler, Marcin Bartłomiejczyk, Marcin Braun, Marcin Mycko, Joanna Madzio, Ewa Polakowska, Edyta Ulińska, Michał Matysiak, Katarzyna Derwich, Monika Lejman, Jerzy Kowalczyk, Wanda Badowska, Bernarda Kazanowska, Tomasz Szczepański, Jan Styczyński, Nina Irga-Jaworska, Wojciech Młynarski

https://doi.org/10.3324/haematol.2017.181198

IGHV segment utilization in immunoglobulin gene rearrangement differentiates patients with anti-myelin-associated glycoprotein neuropathy from others immunoglobulin M-gammopathies (404 Online Views)

Jean-Sebastien Allain, Florian Thonier, Morgane Pihan, Marie-Laure Boulland, Sophie de Guibert, Vincent Launay, Anne-Violaine Doncker, Michel Ganard, Amyra Aliouat, Céline Pangault, Roch Houot, Marie De Tayrac, Thierry Lamy, Mikael Roussel, Thierry Fest, Olivier Decaux, Cedric Pastoret

https://doi.org/10.3324/haematol.2017.177444

Outcomes of patients with relapsed aggressive adult T-cell leukemia-lymphoma: clinical effectiveness of anti-CCR4 antibody and allogeneic hematopoietic stem cell transplantation (269 Online Views)

Shigeo Fuji, Atae Utsunomiya, Yoshitaka Inoue, Takashi Miyagi, Satsuki Owatari, Yasushi Sawayama, Yukiyoshi Moriuchi, Ilseung Choi, Takero Shindo, Shin-ichiro Yoshida, Satoshi Yamasaki, Takuhiro Yamaguchi, Takahiro Fukuda

https://doi.org/10.3324/haematol.2017.184564

Sequential loss of tumor surface antigens following chimeric antigen receptor T-cell therapies in diffuse large B-cell lymphoma (470 Online Views)

Haneen Shalabi, Ira L. Kraft, Hao-Wei Wang, Constance M. Yuan, Bonnie Yates, Cindy Delbrook, Julie D. Zimbelman, Roger Giller, Maryalice Stetler-Stevenson, Elaine S. Jaffe, Daniel W. Lee, Jack F. Shern, Terry J. Fry, Nirali N. Shah

https://doi.org/10.3324/haematol.2017.183459