CURRENT ISSUE
April, 2025
No. 110 (4)

Landmark papers in Hematology

Editorials

Review Series

Myeloproliferative Neoplasms

Articles

Acute Lymphoblastic Leukemia

Cyclin C promotes development and progression of B-cell acute lymphoblastic leukemia by counteracting p53-mediated stress responses (1147 Online Views)

Jana Trifinopoulos, Julia List, Thorsten Klampfl, Klara Klein, Michaela Prchal-Murphy, Agnieszka Witalisz-Siepracka, Florian Bellutti, Luca L. Fava, Gerwin Heller, Sarah Stummer, Patricia Testori, Monique L. den Boer, Judith M. Boer, Sonja Marinovic, Gregor Hoermann, Wencke Walter, Andreas Villunger, Piotr Sicinski, Veronika Sexl, Dagmar Gotthardt

https://doi.org/10.3324/haematol.2024.285701

Acute Myeloid Leukemia

Acute myeloid leukemia drug-tolerant persister cells survive chemotherapy by transiently increasing plasma membrane rigidity, that also increases their sensitivity to immune cell killing (1150 Online Views)

Yael Morgenstern, JongBok Lee, Yoosu Na, Brandon Y. Lieng, Nicholas S. Ly, William D. Gwynne, Rose Hurren, Li Ma, Dakai Ling, Marcela Gronda, Andrea Arruda, Avraham Frisch, Tsila Zuckerman, Yishai Ofran, Mark D. Minden, Li Zhang, Catherine O’Brien, Andrew T. Quaile, J. Rafael Montenegro-Burke, Aaron D. Schimmer

https://doi.org/10.3324/haematol.2024.286018

Chronic Lymphocytic Leukemia

Investigating the influence of germline ATM variants in chronic lymphocytic leukemia on cancer vulnerability (1098 Online Views)

Roberta S. Azevedo, Francesca Morelli, Kiyomi Mashima, Rayan Fardoun, Svitlana Tyekucheva, Stacey Fernandes, Samantha Shupe, Marissa Terra, Anisha Patel, Matthew S. Davids, Joseph Yu, Jennifer R. Brown

https://doi.org/10.3324/haematol.2024.286031

Hemostasis

Intracranial hemorrhage before start of prophylaxis in children with hemophilia: incidence, timing, and potential for prevention (878 Online Views)

Nadine G. Andersson, Marloes de Kovel, Giancarlo Castaman, Roseline d’Oiron, Gili Kenet, Christoph Konigs, Christoph Male, Beatrice Nolan, Martin Olivieri, Fernando Pinto, Sigridur Sigurgisladottir, Ester Zapotocka, Kathelijn Fischer

https://doi.org/10.3324/haematol.2024.285874

A fully humanized von Willebrand disease type 1 mouse model as unique platform to investigate novel therapeutic options (976 Online Views)

Genevieve McCluskey, Marco Heestermans, Ivan Peyron, Eloise Pascal, Marie Clavel, Eric Bun, Emilie Bocquet, Christelle Reperant, Sophie Susen, Olivier D. Christophe, Cecile V. Denis, Peter J. Lenting, Caterina Casari

https://doi.org/10.3324/haematol.2024.286076

Myeloproliferative Disorders

Plasma Cell Disorders

A novel CCL3-HMGB1 signaling axis regulating osteocyte RANKL expression in multiple myeloma (866 Online Views)

Aric Anloague, Hayley M. Sabol, Japneet Kaur, Sharmin Khan, Cody Ashby, Carolina Schinke, C. Lowry Barnes, Farah Alturkmani, Elena Ambrogini, Michael Tveden Gundesen, Thomas Lund, Anne Kristine Amstrup, Thomas Levin Andersen, Marta Diaz-delCastillo, G. David Roodman, Teresita Bellido, Jesus Delgado-Calle

https://doi.org/10.3324/haematol.2024.286484

Letters to the Editor

Depletion of the RNA binding protein QKI and circular RNA dysregulation in T-cell acute lymphoblastic leukemia (815 Online Views)

Alessia Buratin, Bruno Palhais, Enrico Gaffo, Juliette Roels, Julie Morscio, Jolien Van Laere, Silvia Orsi, Geertruij te Kronnie, Pieter Van Vlierberghe, Panagiotis Ntziachristos, Stefania Bortoluzzi

https://doi.org/10.3324/haematol.2024.285971

FLT3 ligand kinetic profile predicts response to treatment in patients with high-risk myelodysplastic syndrome/chronic myelomonocytic leukemia receiving CPX-351: a study from the Groupe Francophone des Myélodysplasies (649 Online Views)

Pierre Peterlin, Joëlle Gaschet, Pascal Turlure, Marie-Pierre Gourin, Pierre-Yves Dumas, Sylvain Thepot, Ana Berceanu, Sophie Park, Marie-Anne Hospital, Thomas Cluzeau, Jose-Miguel Torregrosa-Diaz, Louis Drevon, Rosa Sapena, Fatiha Chermat, Lionel Ades, Sophie Dimicoli-Salazar, Maxime Jullien, Pierre Fenaux, Patrice Chevallier.

https://doi.org/10.3324/haematol.2024.286025

Donor cytomegalovirus serology impacts overall survival in children receiving first unrelated hematopoietic stem cell transplant for acute leukemia: European Society of Bone Marrow Transplantation Pediatric Diseases Working Party Study (752 Online Views)

Elif Ince, Jaques-Emmanuel Galimard, Marianne Ifversen, Arnaud Dalissier, Zofia Szmit, Oana Mirci-Danicar, Franco Locatelli, Petr Sedlacek, Jan Styczynski, Jean-Hugues Dalle, Cecile Renard, Adriana Balduzzi, Arjan Lankester, Marc Bierings, Franca Fagioli, Katrine Kielsen, Fanny Rialland, Jochen Büchner, Mervi Taskinen, Robert Wynn, Charlotte Jubert, Gérard Michel, Herbert Pichler, Gergely Krivan, Simone Cesaro, Selim Corbacioglu, Roland Meisel, Krzysztof Kalwak

https://doi.org/10.3324/haematol.2024.286082

Teclistamab in relapsed refractory multiple myeloma: a multi-institutional real-world study from the French early access program (1265 Online Views)

Aurore Perrot, Cyrille Hulin, Ariane Boumendil, Hamza Manjra, Antoine Leveque, Carolyne Croizier, Arthur Dony, Mohamad Mohty, Murielle Roussel, Salomon Manier, Frédérique Orsini-Piocelle, Loic Bauschert, Arthur Bobin, Laurent Frenzel, Laure Vincent, Claire Breal, Jean Richard Eveillard, Thomas Gerome, Mourad Tiab, Emilie Chalayer, Rakiba Belkhir, Clara Mariette, Perrine Moyer, Thomas Chalopin, Brieuc Cherel, Lydia Montes, Arthur Coste, Reza Tabrizi, Lionel Karlin, Daniella Robu, Amandine Huguet, Stéphanie Harel, Philippe Moreau

https://doi.org/10.3324/haematol.2024.286118

Dexamethasone is associated with reduced frequency and intensity of cytokine release syndrome compared with alternative corticosteroid regimens as premedication for glofitamab in patients with relapsed/refractory large B-cell lymphoma (1249 Online Views)

Lorenzo Falchi, Martin Hutchings, Carmelo Carlo-Stella, Franck Morschhauser, Michael Dickinson, Guillaume Cartron, Cyrus Khan, Monica Tani, Joaquin Martinez-Lopez, Nancy L. Bartlett, Antonio Salar, Joshua D. Brody, Sirpa Leppä, Aurelien Berthier, Martine Kallemeijn, James Relf, Fabiola Bene Tchaleu, Linda Lundberg, Emmanuel Bachy.

https://doi.org/10.3324/haematol.2024.286257

Letermovir prophylaxis for cytomegalovirus is associated with risk of post-transplant lymphoproliferative disorders after haploidentical stem cell transplantation (1032 Online Views)

Xu-Ying Pei, Qiang Huang, Ling-Jie Luo, Hai-Lu Sun, Jing Liu, Yu-Qian Sun, Xiao-Dong Mo, Meng Lv, Dai-Hong Liu, Hong-Yan Ma, Yan-Wei Wu, Lan-Ping Xu, Yu Wang, Xiao-Hui Zhang, Liang Chen, Xiao-Jun Huang

https://doi.org/10.3324/haematol.2024.286265

Germline genetics, disease, and exposure to medication influence longitudinal dynamics of clonal hematopoiesis (1255 Online Views)

Taralynn Mack, Yash Pershad, Caitlyn Vlasschaert, Cosmin A. Bejan, Jonathan Brett Heimlich, Yajing Li, Nicole A. Mickels, Joseph C. Van Amburg, Jessica Ulloa, Alexander J. Silver, Leo Y. Luo, Angela Jones, Paul Brent Ferrell, Ashwin Kishtagari, Yaomin Xu, Michael R. Savona, Alexander G. Bick

https://doi.org/10.3324/haematol.2024.286513

Calaspargase pegol and pegaspargase cause similar hepatosteatosis in mice (412 Online Views)

Veronica Ruiz-Torres, Jennifer J. Chia, Michael Cohen, Jia Tan, Teresa Rushing, Jose Tinajero, Etan Orgel, Steven D. Mittelman

https://doi.org/10.3324/haematol.2024.286549

Identification of a clinicopathologic prognostic index for newly diagnosed large B-cell lymphoma patients treated with R-CHOP (624 Online Views)

Vincent Ni, Sunita D. Nasta, Stefan K. Barta, Stephen J. Schuster, Elise A. Chong, Jakub Svoboda, Jennifer J.D. Morrissette, Ashley Barlev, Adam Bagg, Salvatore F. Priore, Daniel J. Landsburg

https://doi.org/10.3324/haematol.2024.286560

Isatuximab, pomalidomide, and dexamethasone as salvage therapy for patients with multiple myeloma: the Italian, multicenter, retrospective clinical experience with 270 cases outside of controlled clinical trials (1398 Online Views)

Enrica Antonia Martino, Daniele Derudas, Elena Rossi, Sofia Terlizzi, Giovanni Reddiconto, Paola Stefanoni, Jacopo Micozzi, Silvia Mangiacavalli, Elena Zamagni, Massimo Offidani, Anna Furlan, Gabriele Buda, Flavia Lotti, Carmine Liberatore, Antonio Lazzaro, Roberta Della Pepa, Giuseppe Bertuglia, Emiliano Barbieri, Concetta Conticello, Claudio De Magistris, Lorenzo De Paoli, Velia Bongarzoni, Anna Maria Cafro, Anna Mele, Pietro Benvenuti, Claudio Cerchione, Cirino Botta, Elisabetta Antonioli, Nicola Sgherza, Sara Aquino, Giuseppe Mele, Gregorio Barilà, Salvatore Palmieri, Ombretta Annibali, Rosario Bianco, Massimiliano Arangio Febbo, Gloria Margiotta Casaluci, Angela Rago, Raffaele Fontana, Francesca Farina, Ernesto Vigna, Antonella Bruzzese, Katia Mancuso, Davide Nappi, Sonia Morè, Elena Rivolti, Catello Califano, Angela Amendola, Daniela Roccotelli, Alessandra Lombardo, Annalisa Citro, Giuseppina Uccello, Renato Zambello, Alessandro Maggi, Santo Neri, Michele Monachesi, Alessandro Gozzetti, Vittorio Montefusco, Marino Brunori, Emilia Cotzia, Giuseppe Pietrantuono, Angela Maria Quinto, Valeria Amico, Nicola Di Renzo, Marta Coscia, Monica Galli, Valerio De Stefano, Maria Teresa Petrucci, Antonino Neri, Francesco Di Raimondo, Fortunato Morabito, Pellegrino Musto, Massimo Gentile

https://doi.org/10.3324/haematol.2024.286658

Case Reports

Intestinal perforation following allogeneic stem cell transplantation caused by Epstein-Barr virus-positive mucocutaneous ulcer (431 Online Views)

Klaus Hirschbühl, Tina Schaller, Bruno Märkl, Adriana Amerein, Michael Gebhard, Georg Braun, Susanne Wasserberg, Elisa Sala, Martin Trepel, Christoph Schmid

https://doi.org/10.3324/haematol.2024.286488

Complete remission of NUP98 fusion-positive acute myeloid leukemia with the covalent menin inhibitor BMF-219, icovamenib (916 Online Views)

Hetty E. Carraway, Joy Nakitandwe, Alexandru Cacovean, Yan Ma, Brian Munneke, Ganesh Waghmare, Clarissa Mandap, Uzma Ahmed, Nicole Kowalczyk, Thomas Butler, Stephan W. Morris

https://doi.org/10.3324/haematol.2024.286537

Erratum

Erratum to: Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin’s lymphoma B cells (153 Online Views)

Guillaume Jacquemin, Virginie Granci, Anne Sophie Gallouet, Najoua Lalaoui, Aymeric Morlé, Elisabetta Iessi, Alexandre Morizot, Carmen Garrido, Thierry Guillaudeux, Olivier Micheau

https://doi.org/10.3324/haematol.2024.287014

Erratum to: Bendamustine and rituximab as first-line treatment for symptomatic splenic marginal zone lymphoma: long-term outcome and impact of early unmeasurable minimal residual disease attainment from the BRISMA/IELSG36 phase II study (253 Online Views)

Emilio Iannitto, Simone Ferrero, Côme Bommier, Daniela Drandi, Martina Ferrante, Krimo Bouabdallah, Sylvain Carras, Guido Gini, Vincent Camus, Salvatrice Mancuso, Luigi Marcheselli, Angela Ferrari, Michele Merli, Benoit Tessoulin, Caterina Stelitano, Kheira Beldjord, Giovanni Roti, Fabrice Jardin, Barbara Castagnari, Francesca Palombi, Lucile Baseggio, Alexandra Traverse-Glehen, Claudio Tripodo, Anna Marina Liberati, Margherita Parolini, Sara Usai, Caterina Patti, Massimo Federico, Maurizio Musso, Marco Ladetto, Emanuele Zucca, Catherine Thieblemont

https://doi.org/10.3324/haematol.2024.287031