Vol. 105 No. 7 (2020): July, 2020

Xing Fan, Chuanfeng Wu, Lauren L. Truitt, Diego A. Espinoza, Stephanie Sellers, Aylin Bonifacino, Yifan Zhou, Stefan F. Cordes, Allen Krouse, Mark Metzger, Robert E. Donahue, Rong Lu, Cynthia E. Dunbar

https://doi.org/10.3324/haematol.2019.231811

Characterization and genotype-phenotype correlation of patients with Fanconi anemia in a multi-ethnic population (3166 Online Views)

Orna Steinberg-Shemer, Tracie A. Goldberg, Joanne Yacobovich, Carina Levin, Ariel Koren, Shoshana Revel-Vilk, Tal Ben-Ami, Amir A. Kuperman, Vered Shkalim Zemer, Amos Toren, Joseph Kapelushnik, Ayelet Ben-Barak, Hagit Miskin, Tanya Krasnov, Sharon Noy-Lotan, Orly Dgany, Hannah Tamary

https://doi.org/10.3324/haematol.2019.222877

Minihepcidins improve ineffective erythropoiesis and splenomegaly in a new mouse model of adult β-thalassemia major (2862 Online Views)

Carla Casu, Roberta Chessa, Alison Liu, Ritama Gupta, Hal Drakesmith, Robert Fleming, Yelena Z. Ginzburg, Brian MacDonald, Stefano Rivella

https://doi.org/10.3324/haematol.2018.212589

Src family kinase-mediated vesicle trafficking is critical for neutrophil basement membrane penetration (1970 Online Views)

Ina Rohwedder, Angela R.M. Kurz, Monika Pruenster, Roland Immler, Robert Pick, Tanja Eggersmann, Sarah Klapproth, Jennifer L. Johnson, Sergi Masgrau Alsina, Clifford A. Lowell, Attila Mócsai, Sergio D. Catz, Markus Sperandio

https://doi.org/10.3324/haematol.2019.225722

Transforming activities of the NUP98-KMT2A fusion gene associated with myelodysplasia and acute myeloid leukemia (1549 Online Views)

James N. Fisher, Angeliki Thanasopoulou, Sabine Juge, Alexandar Tzankov, Frederik O. Bagger, Max A. Mendez, Antoine H.F.M. Peters, Juerg Schwaller

https://doi.org/10.3324/haematol.2019.219188

Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients (2502 Online Views)

Iva Truxova, Lenka Kasikova, Cyril Salek, Michal Hensler, Daniel Lysak, Peter Holicek, Pavla Bilkova, Monika Holubova, Xiufen Chen, Romana Mikyskova, Milan Reinis, Marek Kovar, Barbora Tomalova, Justin P. Kline, Lorenzo Galluzzi, Radek Spisek, Jitka Fucikova

https://doi.org/10.3324/haematol.2019.223933

Bortezomib with standard chemotherapy for children with acute myeloid leukemia does not improve treatment outcomes: a report from the Children’s Oncology Group (5651 Online Views)

Richard Aplenc, Soheil Meshinchi, Lillian Sung, Todd Alonzo, John Choi, Brian Fisher, Robert Gerbing, Betsy Hirsch, Terzah Horton, Samir Kahwash, John Levine, Michael Loken, Lisa Brodersen, Jessica Pollard, Susana Raimondi, Edward Anders Kolb, Alan Gamis

https://doi.org/10.3324/haematol.2019.220962

Relapses and treatment-related events contributed equally to poor prognosis in children with ABL-class fusion positive B-cell acute lymphoblastic leukemia treated according to AIEOP-BFM protocols (2905 Online Views)

Gunnar Cario, Veronica Leoni, Valentino Conter, Andishe Attarbaschi, Marketa Zaliova, Lucie Sramkova, Gianni Cazzaniga, Grazia Fazio, Rosemary Sutton, Sarah Elitzur, Shai Izraeli, Melchior Lauten, Franco Locatelli, Giuseppe Basso, Barbara Buldini, Anke K. Bergmann, Jana Lentes, Doris Steinemann, Gudrun Göhring, Brigitte Schlegelberger, Oskar A. Haas, Denis Schewe, Swantje Buchmann, Anja Moericke, Deborah White, Tamas Revesz, Martin Stanulla, Georg Mann, Nicole Bodmer, Nira Arad-Cohen, Jan Zuna, Maria Grazia Valsecchi, Martin Zimmermann, Martin Schrappe, Andrea Biondi

https://doi.org/10.3324/haematol.2019.231720

Genetic and phenotypic characterization of indolent T-cell lymphoproliferative disorders of the gastrointestinal tract (2876 Online Views)

Craig R. Soderquist, Nupam Patel, Vundavalli V. Murty, Shane Betman, Nidhi Aggarwal, Ken H. Young, Luc Xerri, Rebecca Leeman-Neill, Suzanne K. Lewis, Peter H. Green, Susan Hsiao, Mahesh M. Mansukhani, Eric D. Hsi, Laurence de Leval, Bachir Alobeid, Govind Bhagat

https://doi.org/10.3324/haematol.2019.230961

Pre-treatment maximum standardized uptake value predicts outcome after frontline therapy in patients with advanced stage follicular lymphoma (6329 Online Views)

Paolo Strati, Mohamed Amin Ahmed, Nathan H. Fowler, Loretta J. Nastoupil, Felipe Samaniego, Luis E. Fayad, Fredrick B. Hagemeister, Jorge E. Romaguera, Alma Rodriguez, Michael Wang, Jason R. Westin, Chan Cheah, Mansoor Noorani, Lei Feng, Richard E. Davis, Sattva S. Neelapu

https://doi.org/10.3324/haematol.2019.230649

Efficacy of central nervous system prophylaxis with stand-alone intrathecal chemotherapy in diffuse large B-cell lymphoma patients treated with anthracycline-based chemotherapy in the rituximab era: a systematic review (5817 Online Views)

Toby A. Eyre, Faouzi Djebbari, Amy A. Kirkwood, Graham P. Collins

https://doi.org/10.3324/haematol.2019.229948

Multiple myeloma exploits Jagged1 and Jagged2 to promote intrinsic and bone marrow-dependent drug resistance (2625 Online Views)

Michela Colombo, Silvia Garavelli, Mara Mazzola, Natalia Platonova, Domenica Giannandrea, Raffaella Colella, Luana Apicella, Marialuigia Lancellotti, Elena Lesma, Silvia Ancona, Maria Teresa Palano, Marzia Barbieri, Elisa Taiana, Elisa Lazzari, Andrea Basile, Mauro Turrini, Anna Pistocchi, Antonino Neri, Raffaella Chiaramonte

https://doi.org/10.3324/haematol.2019.221077

Lenalidomide-based induction and maintenance in elderly newly diagnosed multiple myeloma patients: updated results of the EMN01 randomized trial (3411 Online Views)

Sara Bringhen, Mattia D’Agostino, Laura Paris, Stelvio Ballanti, Norbert Pescosta, Stefano Spada, Sara Pezzatti, Mariella Grasso, Delia Rota-Scalabrini, Luca De Rosa, Vincenzo Pavone, Giulia Gazzera, Sara Aquino, Marco Poggiu, Armando Santoro, Massimo Gentile, Luca Baldini, Maria Teresa Petrucci, Patrizia Tosi, Roberto Marasca, Claudia Cellini, Antonio Palumbo, Patrizia Falco, Roman Hájek, Mario Boccadoro, Alessandra Larocca

https://doi.org/10.3324/haematol.2019.226407

Antithrombotic prophylaxis for surgery-associated venous thromboembolism risk in patients with inherited platelet disorders. The SPATA-DVT Study (2111 Online Views)

Francesco Paciullo, Loredana Bury, Patrizia Noris, Emanuela Falcinelli, Federica Melazzini, Sara Orsini, Carlo Zaninetti, Rezan Abdul-Kadir, Deborah Obeng-Tuudah, Paula G. Heller, Ana C. Glembotsky, Fabrizio Fabris, Jose Rivera, Maria Luisa Lozano, Nora Butta, Remi Favier, Ana Rosa Cid, Marc Fouassier, Gian Marco Podda, Cristina Santoro, Elvira Grandone, Yvonne Henskens, Paquita Nurden, Barbara Zieger, Adam Cuker, Katrien Devreese, Alberto Tosetto, Erica De Candia, Arnaud Dupuis, Koji Miyazaki, Maha Othman, Paolo Gresele

https://doi.org/10.3324/haematol.2019.227876

Long-term neuropsychological sequelae, emotional wellbeing and quality of life in patients with acquired thrombotic thrombocytopenic purpura (2801 Online Views)

Silvia Riva, Ilaria Mancini, Alberto Maino, Barbara Ferrari, Andrea Artoni, Pasquale Agosti, Flora Peyvandi

https://doi.org/10.3324/haematol.2019.226423

Fibrinogen gamma gene rs2066865 and risk of cancer-related venous thromboembolism (1880 Online Views)

Benedikte Paulsen, Hanne Skille, Erin N. Smith, Kristian Hveem, Maiken E. Gabrielsen, Sigrid K. Brækkan, Frits R. Rosendaal, Kelly A. Frazer, Olga V. Gran, John-Bjarne Hansen

https://doi.org/10.3324/haematol.2019.224279

Bleeding disorders in adolescents with heavy menstrual bleeding in a multicenter prospective US cohort (3487 Online Views)

Ayesha Zia, Shilpa Jain, Peter Kouides, Song Zhang, Ang Gao, Niavana Salas, May Lau, Ellen Wilson, Nicole DeSimone, Ravi Sarode

https://doi.org/10.3324/haematol.2019.225656

Association of uric acid levels before start of conditioning with mortality after allogeneic hematopoietic stem cell transplantation – a prospective, non-interventional study of the EBMT Transplant Complication Working Party (1505 Online Views)

Olaf Penack, Christophe Peczynski, Steffie van der Werf, Jürgen Finke, Arnold Ganser, Helene Schoemans, Jiri Pavlu, Riitta Niittyvuopio, Wilfried Schroyens, Leylagül Kaynar, Igor W. Blau, Walter van der Velden, Jorge Sierra, Agostino Cortelezzi, Gerald Wulf, Pascal Turlure, Montserat Rovira, Zubeydenur Ozkurt, Maria J. Pascual-Cascon, Maria C. Moreira, Johannes Clausen, Hildegard Greinix, Rafael F. Duarte, Grzegorz W. Basak

https://doi.org/10.3324/haematol.2019.228668

International recommendations on the diagnosis and treatment of acquired hemophilia A (57156 Online Views)

Andreas Tiede, Peter Collins, Paul Knoebl, Jerome Teitel, Craig Kessler, Midori Shima, Giovanni Di Minno, Roseline d’Oiron, Peter Salaj, Victor Jiménez-Yuste, Angela Huth-Kühne, Paul Giangrande

https://doi.org/10.3324/haematol.2019.230771

Kinetics of cytokine receptor internalization under steady-state conditions affects growth of neighboring blood cells (1889 Online Views)

Akiko Nagamachi, Jiro Kikuchi, Akinori Kanai, Yusuke Furukawa, Toshiya Inaba

https://doi.org/10.3324/haematol.2019.232959

Hematopoietic alterations in chronic heart failure patients by somatic mutations leading to clonal hematopoiesis (1702 Online Views)

Lena Dorsheimer, Birgit Assmus, Tina Rasper, Christina A. Ortmann, Khalil Abou-El-Ardat, Katharina C. Kiefer, Jedrzej Hoffmann, Florian Seeger, Halvard Bonig, Stefanie Dimmeler, Andreas M. Zeiher, Michael A. Rieger

https://doi.org/10.3324/haematol.2019.224402

Aplastic anemia related to thymoma: a survey on behalf of the French reference center of aplastic anemia and a review of the literature (2033 Online Views)

Nicolas Gendron, Flore Sicre de Fontbrune, Alice Guyard, Jehane Fadlallah, Sylvain Chantepie, Maud D’Aveni, Ronan Le Calloch, Alice Garnier, Marie-Anne Couturier, Véronique Morel, Claire Bernard, Louis Terriou, Estibaliz Lazaro, Gérard Socié, Régis Peffault de Latour

https://doi.org/10.3324/haematol.2019.226134

Predisposed genomic instability in pre-treatment bone marrow evolves to therapy-related myeloid neoplasms in malignant lymphoma (910 Online Views)

Seiichiro Katagiri, Hideki Makishima, Kenko Azuma, Yasuhito Nannya, Yuu Saitoh, Seiichiro Yoshizawa, Daigo Akahane, Hiroaki Fujimoto, Yoshikazu Ito, Ravi Velaga, Tomohiro Umezu, Junko H. Ohyashiki, Seishi Ogawa, Kazuma Ohyashiki

https://doi.org/10.3324/haematol.2019.229856

Acute erythroid leukemias have a distinct molecular hierarchy from non-erythroid acute myeloid leukemias (1477 Online Views)

Nathalie Cervera, Anne-Catherine Lhoumeau, José Adélaïde, Arnaud Guille, Anne Murati, Marie-Joëlle Mozziconacci, Norbert Vey, Daniel Birnbaum, Véronique Gelsi-Boyer

https://doi.org/10.3324/haematol.2019.231142

circASXL1-1 regulates BAP1 deubiquitinase activity in leukemia (1433 Online Views)

Shweta Pradip Jadhav, Nishi Kumari, Larry Ng, Pei Fang Tan, Nicole Shu Ling Yeo-Teh, Yufen Goh, Wee Nih Fam, Jia Qi Tng, Johann Shane Tian, Bryan T. H. Koh, Chan Ming Chun, Wilson Wang, Wee Joo Chng, Melissa Jane Fullwood, Ernesto Guccione, Neerja Karnani, Daniel G. Tenen, Sudhakar Jha

https://doi.org/10.3324/haematol.2019.225961

A multicenter prospective study of first-line antibiotic therapy for early-stage gastric mucosa-associated lymphoid tissue lymphoma and diffuse large B-cell lymphoma with histological evidence of mucosa-associated lymphoid tissue (1379 Online Views)

Hui-Jen Tsai, John Jen Tai, Li-Tzong Chen, Ming-Shiang Wu, Kun-Huei Yeh, Chung-Wu Lin, Tsang-En Wang, Hsiu-Po Wang, Fang-Jung Yu, Jyh-Ming Liou, Chin-Fu Hsiao, Tsu-Yao Cheng, Hong-Jen Yeh, Chung-Wang Ko, Ming-Jen Chen, Gin-Ho Lo, Ping-I Hsu, Cheng-Shyong Chang, Wei-Shou Hwang, Shih-Sung Chuang, Hsiao-Wei Lee, Chia-Tung Shun, Chang-Fang Chiu, Wen-Ming Wang, Ching-Yun Hsieh, Tsang-Wu Liu, Jaw-Town Lin, Sung-Hsin Kuo, Ann-Lii Cheng, for the Taiwan Cooperative Oncology Group

https://doi.org/10.3324/haematol.2019.228775

New paradigm for radiation in multiple myeloma: lower yet effective dose to avoid radiation toxicity (4274 Online Views)

Adnan Elhammali, Behrang Amini, Ethan B. Ludmir, Jillian R. Gunther, Sarah A. Milgrom, Chelsea C. Pinnix, Therese Andraos, Alison Yoder, Donna Weber, Robert Orlowski, Elisabet Manasanch, Krina Patel, Paolo Strati, Ranjit Nair, Hans C. Lee, Sheeba Thomas, Swaminathan Iyer, Gregory Kaufmann, Naveen Garg, Bouthaina S. Dabaja

https://doi.org/10.3324/haematol.2019.235804

Genetic variation of platelet glycoprotein VI and the risk of venous thromboembolism (1023 Online Views)

Hanne Skille, Benedikte Paulsen, Kristian Hveem, Maiken E. Gabrielsen, Ben Brumpton, Kristian Hindberg, Olga V. Gran, Frits R. Rosendaal, Sigrid K. Brækkan, John-Bjarne Hansen

https://doi.org/10.3324/haematol.2019.231225

Severe bleeding and absent ADP-induced platelet aggregation associated with inherited combined CalDAG-GEFI and P2Y12 deficiencies (3297 Online Views)

Barbara Lunghi, Anna Lecchi, Rosa Santacroce, Mariangela Scavone, Rita Paniccia, Andrea Artoni, Christian Gachet, Giancarlo Castaman, Maurizio Margaglione, Francesco Bernardi, Marco Cattaneo

https://doi.org/10.3324/haematol.2019.232850

Rare variants lowering the levels of coagulation factor X are protective against ischemic heart disease (1690 Online Views)

Elvezia Maria Paraboschi, Amit Vikram Khera, Piera Angelica Merlini, Laura Gigante, Flora Peyvandi, Mark Chaffin, Marzia Menegatti, Fabiana Busti, Domenico Girelli, Nicola Martinelli, Oliviero Olivieri, Sekar Kathiresan, Diego Ardissino, Rosanna Asselta, Stefano Duga

https://doi.org/10.3324/haematol.2019.237750