July, 2016
No. 101 (7)

Editorials

Review Articles

Articles

Hematopoiesis

Human thrombopoiesis depends on Protein kinase Cδ/protein kinase Cε functional couple (266 Online Views)

Cecilia Carubbi, Elena Masselli, Silvia Martini, Daniela Galli, Franco Aversa, Prisco Mirandola, Joseph E. Italiano, Giuliana Gobbi, Marco Vitale

https://doi.org/10.3324/haematol.2015.137984

Myeloproliferative Disorders

Ruxolitinib versus best available therapy in patients with polycythemia vera: 80-week follow-up from the RESPONSE trial (870 Online Views)

Srdan Verstovsek, Alessandro M. Vannucchi, Martin Griesshammer, Tamas Masszi, Simon Durrant, Francesco Passamonti, Claire N. Harrison, Fabrizio Pane, Pierre Zachee, Keita Kirito, Carlos Besses, Masayuki Hino, Beatriz Moiraghi, Carole B. Miller, Mario Cazzola, Vittorio Rosti, Igor Blau, Ruben Mesa, Mark M. Jones, Huiling Zhen, Jingjin Li, Nathalie Francillard, Dany Habr, Jean-Jacques Kiladjian

https://doi.org/10.3324/haematol.2016.143644

Chronic Myeloid Leukemia

Acute Myeloid Leukemia

Salvage therapy with high-dose cytarabine and mitoxantrone in combination with all-trans retinoic acid and gemtuzumab ozogamicin in acute myeloid leukemia refractory to first induction therapy (334 Online Views)

Marie-Luise Hütter-Krönke, Axel Benner, Konstanze Döhner, Jürgen Krauter, Daniela Weber, Margit Moessner, Claus-Henning Köhne, Heinz A. Horst, Ingo G.H. Schmidt-Wolf, Mathias Rummel, Katharina Götze, Elisabeth Koller, Andreas L. Petzer, Hans Salwender, Walter Fiedler, Heinz Kirchen, Detlef Haase, Stephan Kremers, Matthias Theobald, Axel C. Matzdorff, Arnold Ganser, Hartmut Döhner, Richard F. Schlenk

https://doi.org/10.3324/haematol.2015.141622

Whole exome sequencing reveals a C-terminal germline variant in CEBPA-associated acute myeloid leukemia: 45-year follow up of a large family (408 Online Views)

Anand Pathak, Katja Seipel, Alexander Pemov, Ramita Dewan, Christina Brown, Sarangan Ravichandran, Brian T. Luke, Michael Malasky, Shalabh Suman, Meredith Yeager, NCI DCEG Cancer Genomics Research Laboratory, NCI DCEG Cancer Sequencing Working Group, Richard A. Gatti, Neil E. Caporaso, John J. Mulvihill, Lynn R. Goldin, Thomas Pabst, Mary L. McMaster, Douglas R. Stewart

https://doi.org/10.3324/haematol.2015.130799

Hodgkin Lymphoma

Whole exome sequencing in families at high risk for Hodgkin lymphoma: identification of a predisposing mutation in the KDR gene (348 Online Views)

Melissa Rotunno, Mary L. McMaster, Joseph Boland, Sara Bass, Xijun Zhang, Laurie Burdett, Belynda Hicks, Sarangan Ravichandran, Brian T. Luke, Meredith Yeager, Laura Fontaine, Paula L. Hyland, Alisa M. Goldstein, NCI DCEG Cancer Sequencing Working Group, NCI DCEG Cancer Genomics Research Laboratory, Stephen J. Chanock, Neil E. Caporaso, Margaret A. Tucker, Lynn R. Goldin

https://doi.org/10.3324/haematol.2015.135475

Non-Hodgkin Lymphoma

N-terminally truncated FOXP1 protein expression and alternate internal FOXP1 promoter usage in normal and malignant B cells (304 Online Views)

Philip J. Brown, Duncan M. Gascoyne, Linden Lyne, Hayley Spearman, Suet Ling Felce, Nora McFadden, Probir Chakravarty, Sharon Barrans, Steven Lynham, Dinis P. Calado, Malcolm Ward, Alison H. Banham

https://doi.org/10.3324/haematol.2016.142141

Plasma Cell Disorders

Analysis of renal impairment in MM-003, a phase III study of pomalidomide + low - dose dexamethasone versus high - dose dexamethasone in refractory or relapsed and refractory multiple myeloma (258 Online Views)

Katja C. Weisel, Meletios A. Dimopoulos, Philippe Moreau, Martha Q. Lacy, Kevin W. Song, Michel Delforge, Lionel Karlin, Hartmut Goldschmidt, Anne Banos, Albert Oriol, Adrian Alegre, Christine Chen, Michele Cavo, Laurent Garderet, Valentina Ivanova, Joaquin Martinez-Lopez, Stefan Knop, Xin Yu, Kevin Hong, Lars Sternas, Christian Jacques, Mohamed H. Zaki, Jesus San Miguel

https://doi.org/10.3324/haematol.2015.137083

Stem Cell Transplantation

Clinical activity of azacitidine in patients who relapse after allogeneic stem cell transplantation for acute myeloid leukemia (553 Online Views)

Charles Craddock, Myriam Labopin, Marie Robin, Juergen Finke, Patrice Chevallier, Ibrahim Yakoub-Agha, Jean Henri Bourhis, Henrik Sengelov, Didier Blaise, Thomas Luft, Michael Hallek, Nicolaus Kröger, Arnon Nagler, Mohamad Mohty

https://doi.org/10.3324/haematol.2015.140996

Unrelated alternative donor transplantation for severe acquired aplastic anemia: a study from the French Society of Bone Marrow Transplantation and Cell Therapies and the EBMT Severe Aplastic Anemia Working Party (350 Online Views)

Raynier Devillier, Jean-Hugues Dalle, Austin Kulasekararaj, Maud D’aveni, Laurence Clément, Alicja Chybicka, Stéphane Vigouroux, Patrice Chevallier, Mickey Koh, Yves Bertrand, Mauricette Michallet, Marco Zecca, Ibrahim Yakoub-Agha, Jean-Yves Cahn, Per Ljungman, Marc Bernard, Pascale Loiseau, Valérie Dubois, Sébastien Maury, Gérard Socié, Carlo Dufour, Regis Peffault de Latour

https://doi.org/10.3324/haematol.2015.138727

Online Only Articles

Tumor suppressors BTG1 and BTG2 regulate early mouse B-cell development (275 Online Views)

Esther Tijchon, Liesbeth van Emst, Laurensia Yuniati, Dorette van Ingen Schenau, Jørn Havinga, Jean-Pierre Rouault, Peter M. Hoogerbrugge, Frank N. van Leeuwen, Blanca Scheijen

https://doi.org/10.3324/haematol.2015.139675

Are somatic mutations predictive of response to erythropoiesis stimulating agents in lower risk myelodysplastic syndromes? (256 Online Views)

Olivier Kosmider, Marie Passet, Valeria Santini, Uwe Platzbecker, Valérie Andrieu, Gina Zini, Odile Beyne-Rauzy, Agnès Guerci, Erico Masala, Enrico Balleari, Ekaterina Bulycheva, François Dreyfus, Pierre Fenaux, Michaela Fontenay, Sophie Park

https://doi.org/10.3324/haematol.2016.142695

Relationship between event-free survival and overall survival in acute myeloid leukemia: a report from SWOG, HOVON/SAKK, and MRC/NCRI (213 Online Views)

Megan Othus, Wim van Putten, Bob Lowenberg, Stephen H. Petersdorf, Sucha Nand, Harry Erba, Frederick Appelbaum, Robert Hills, Nigel Russell, Alan Burnett, Elihu Estey

https://doi.org/10.3324/haematol.2015.138552

A novel mechanism of NPM1 cytoplasmic localization in acute myeloid leukemia: the recurrent gene fusion NPM1–HAUS1 (273 Online Views)

Paulo Vidal Campregher, Welbert de Oliveira Pereira, Bianca Lisboa, Renato Puga, Elvira Rodrigues Pereira Velloso Deolinda, Ricardo Helman, Luciana Cavalheiro Marti, João Carlos Campos Guerra, Kalliopi N. Manola, Roberta Cardoso Petroni, Alanna Mara Pinheiro Sobreira Bezerra, Fernando Ferreira Costa, Nelson Hamerschlak, Fábio Pires de Souza Santos

https://doi.org/10.3324/haematol.2015.137364

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia (122 Online Views)

Anna Wojtuszkiewicz, Yehuda G. Assaraf, Mirthe Hoekstra, Rocco Sciarrillo, Gerrit Jansen, Godefridus J. Peters, Rob Pieters, Edwin Sonneveld, Gabriele Escherich, Gertjan J.L. Kaspers, Jacqueline Cloos

https://doi.org/10.3324/haematol.2016.142794

Phase I study of single-agent CC-292, a highly selective Bruton’s tyrosine kinase inhibitor, in relapsed/refractory chronic lymphocytic leukemia (242 Online Views)

Jennifer R. Brown, Wael A. Harb, Brian T. Hill, Janice Gabrilove, Jeff P. Sharman, Marshall T. Schreeder, Paul M. Barr, James M. Foran, Thomas P. Miller, Jan A. Burger, Kevin R. Kelly, Daruka Mahadevan, Shuo Ma, Yan Li, Daniel W. Pierce, Evelyn Barnett, Jeffrey Marine, Monika Miranda, Ada Azaryan, Xujie Yu, Pilar Nava-Parada, Jay Mei, Thomas J. Kipps

https://doi.org/10.3324/haematol.2015.140806

Additional trisomies amongst patients with chronic lymphocytic leukemia carrying trisomy 12: the accompanying chromosome makes a difference (207 Online Views)

Panagiotis Baliakas, Anna Puiggros, Aliki Xochelli, Lesley-Ann Sutton, Florence Nguyen-Khac, Anne Gardiner, Karla Plevova, Eva Minga, Anastasia Hadzidimitriou, Renata Walewska, Helen McCarthy, Margarita Ortega, Rosa Collado, Teresa González, Isabel Granada, Elisa Luño, Jana Kotašková, Theodoros Moysiadis, Zadie Davis, Niki Stavroyianni, Achilles Anagnostopoulos, Jonathan C. Strefford, Sarka Pospisilova, Frederic Davi, Anastasia Athanasiadou, Richard Rosenquist, David Oscier, Blanca Espinet, Kostas Stamatopoulos

https://doi.org/10.3324/haematol.2015.140202

Associations between B-cell non-Hodgkin lymphoma and exposure, persistence and immune response to hepatitis B (215 Online Views)

Geffen Kleinstern, Rania Abu Seir, Riki Perlman, Ziad Abdeen, Areej Khatib, Husein Elyan, Eldad J. Dann, Meirav Kedmi, Martin Ellis, Arnon Nagler, Gail Amir, Dina Ben Yehuda, Rifaat Safadi, Ora Paltiel

https://doi.org/10.3324/haematol.2016.144840

Newly established myeloma-derived stromal cell line MSP-1 supports multiple myeloma proliferation, migration, and adhesion and induces drug resistance more than normal-derived stroma (265 Online Views)

Pilar de la Puente, Nancy Quan, Ryan Soo Hoo, Barbara Muz, Rebecca C. Gilson, Micah Luderer, Justin King, Samuel Achilefu, Noha Nabil Salama, Ravi Vij, Abdel Kareem Azab

https://doi.org/10.3324/haematol.2016.142190

APRIL levels are associated with disease activity in human chronic graft-versus-host disease (155 Online Views)

François Chasset, Adèle de Masson, Hélène Le Buanec, Aliénor Xhaard, Flore Sicre de Fontbrune, Marie Robin, Michel Rybojad, Nathalie Parquet, Anne C. Brignier, Tereza Coman, Djaouida Bengoufa, Anne Bergeron, Régis Peffault de Latour, Martine Bagot, Armand Bensussan, Gérard Socié, Jean-David Bouaziz

https://doi.org/10.3324/haematol.2016.145409