May, 2016
No. 101 (5)

Editorials

Review Articles

Role of the tumor microenvironment in mature B-cell lymphoid malignancies

Nathan H. Fowler, Chan Yoon Cheah, Randy D. Gascoyne, John Gribben, Sattva S. Neelapu, Paolo Ghia, Catherine Bollard, Stephen Ansell, Michael Curran, Wyndham H. Wilson, Susan O’Brien, Cliona Grant, Richard Little, Thorsten Zenz, Loretta J. Nastoupil, Kieron Dunleavy

https://doi.org/10.3324/haematol.2015.139493

Chronic myeloid leukemia: reminiscences and dreams

Tariq I. Mughal, Jerald P. Radich, Michael W. Deininger, Jane F. Apperley, Timothy P. Hughes, Christine J. Harrison, Carlo Gambacorti-Passerini, Giuseppe Saglio, Jorge Cortes, George Q. Daley

https://doi.org/10.3324/haematol.2015.139337

Articles

Red Cell Biology & Its Disorders

ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia

Nobuto Arashiki, Yuichi Takakuwa, Narla Mohandas, John Hale, Kenichi Yoshida, Hiromi Ogura, Taiju Utsugisawa, Shouichi Ohga, Satoru Miyano, Seishi Ogawa, Seiji Kojima, Hitoshi Kanno

https://doi.org/10.3324/haematol.2016.142273

Blood Transfusion

Metabolic pathways that correlate with post-transfusion circulation of stored murine red blood cells

Karen de Wolski, Xiaoyoun Fu, Larry J. Dumont, John D. Roback, Hayley Waterman, Katherine Odem-Davis, Heather L. Howie, James C. Zimring

https://doi.org/10.3324/haematol.2015.139139

Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components

Roel P. Gazendam, Annemarie van de Geer, John L. van Hamme, Anton T.J. Tool, Dieke J. van Rees, Cathelijn E.M. Aarts, Maartje van den Biggelaar, Floris van Alphen, Paul Verkuijlen, Alexander B. Meijer, Hans Janssen, Dirk Roos, Timo K. van den Berg, Taco W. Kuijpers

https://doi.org/10.3324/haematol.2015.136630

Myeloproliferative Disorders

Long-term serial xenotransplantation of juvenile myelomonocytic leukemia recapitulates human disease in Rag2−/−γc−/− mice

Christopher Felix Krombholz, Konrad Aumann, Matthias Kollek, Daniela Bertele, Silvia Fluhr, Mirjam Kunze, Charlotte M. Niemeyer, Christian Flotho, Miriam Erlacher

https://doi.org/10.3324/haematol.2015.138545

Acute Myeloid Leukemia

Association of acute myeloid leukemia’s most immature phenotype with risk groups and outcomes

Jonathan M. Gerber, Joshua F. Zeidner, Sarah Morse, Amanda L. Blackford, Brandy Perkins, Breann Yanagisawa, Hao Zhang, Laura Morsberger, Judith Karp, Yi Ning, Christopher D. Gocke, Gary L. Rosner, B. Douglas Smith, Richard J. Jones

https://doi.org/10.3324/haematol.2015.135194

Plasma Cell Disorders

Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma

Esther Drent, Richard W.J. Groen, Willy A. Noort, Maria Themeli, Jeroen J. Lammerts van Bueren, Paul W.H.I. Parren, Jürgen Kuball, Zsolt Sebestyen, Huipin Yuan, Joost de Bruijn, Niels W.C.J. van de Donk, Anton C.M. Martens, Henk M. Lokhorst, Tuna Mutis

https://doi.org/10.3324/haematol.2015.137620

Cell Therapy & Immunotherapy

Effects of anti-NKG2A antibody administration on leukemia and normal hematopoietic cells

Loredana Ruggeri, Elena Urbani, Pascale André, Antonella Mancusi, Antonella Tosti, Fabiana Topini, Mathieu Bléry, Lucia Animobono, François Romagné, Nicolai Wagtmann, Andrea Velardi

https://doi.org/10.3324/haematol.2015.135301

Stem Cell Transplantation

Reduced intensity haplo plus single cord transplant compared to double cord transplant: improved engraftment and graft-versus-host disease-free, relapse-free survival

Koen van Besien, Parameswaran Hari, Mei-Jie Zhang, Hong-Tao Liu, Wendy Stock, Lucy Godley, Olatoyosi Odenike, Richard Larson, Michael Bishop, Amittha Wickrema, Usama Gergis, Sebastian Mayer, Tsiporah Shore, Stephanie Tsai, Joanna Rhodes, Melissa M. Cushing, Sandra Korman, Andrew Artz

https://doi.org/10.3324/haematol.2015.138594

Allogeneic unrelated bone marrow transplantation from older donors results in worse prognosis in recipients with aplastic anemia

Yasuyuki Arai, Tadakazu Kondo, Hirohito Yamazaki, Katsuto Takenaka, Junichi Sugita, Takeshi Kobayashi, Yukiyasu Ozawa, Naoyuki Uchida, Koji Iwato, Naoki Kobayashi, Yoshiyuki Takahashi, Ken Ishiyama, Takahiro Fukuda, Tatsuo Ichinohe, Yoshiko Atsuta, Takehiko Mori, Takanori Teshima

https://doi.org/10.3324/haematol.2015.139469

Online Only Articles

Using zebrafish to model erythroid lineage toxicity and regeneration

Anna Lenard, Elisa Alghisi, Hamina Daff, Massimiliano Donzelli, Claudia McGinnis, Claudia Lengerke

https://doi.org/10.3324/haematol.2016.142562

ε-globin expression is regulated by SUV4-20h1

Yadong Wang, Gerhard Rank, Zhuchen Li, Ying Wang, Junyi Ju, Alexander Nuber, Yupeng Wu, Ming Liu, Min Nie, Feifei Huang, Loretta Cerruti, Chi Ma, Renxiang Tan, Gunnar Schotta, Stephen M. Jane, Changjiang K. Zeng, Quan Zhao

https://doi.org/10.3324/haematol.2015.139980

Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels

Suzana Kovac, Preethne Böser, Yifang Cui, Dunja Ferring-Appel, Daniela Casarrubea, Lili Huang, Emma Fung, Andreas Popp, Bernhard K. Mueller, Matthias W. Hentze

https://doi.org/10.3324/haematol.2015.140772

Impaired formation of erythroblastic islands is associated with erythroid failure and poor prognosis in a significant proportion of patients with myelodysplastic syndromes

Guntram Buesche, Huesniye Teoman, Aristoteles Giagounidis, Gudrun Göhring, Brigitte Schlegelberger, Arnold Ganser, Carlo Aul, Hans-Heinrich Kreipe

https://doi.org/10.3324/haematol.2015.129015

Pegylated interferon alpha-2a for essential thrombocythemia during pregnancy: outcome and safety. A case series

Yan Beauverd, Deepti Radia, Catherine Cargo, Steve Knapper, Mark Drummond, Arvind Pillai, Claire Harrison, Susan Robinson

https://doi.org/10.3324/haematol.2015.139691

Acute myeloid leukemia patients’ clinical response to idasanutlin (RG7388) is associated with pre-treatment MDM2 protein expression in leukemic blasts

Bernhard Reis, Lori Jukofsky, Gong Chen, Giovanni Martinelli, Hua Zhong, W. Venus So, Michael J. Dickinson, Mark Drummond, Sarit Assouline, Maneja Hashemyan, Michel Theron, Steven Blotner, Je-Hwan Lee, Margaret Kasner, Sung-Soo Yoon, Ruediger Rueger, Karen Seiter, Steven A. Middleton, Kevin R. Kelly, Norbert Vey, Karen Yee, Gwen Nichols, Lin-Chi Chen, William E. Pierceall

https://doi.org/10.3324/haematol.2015.139717

Activity of the Janus kinase inhibitor ruxolitinib in chronic lymphocytic leukemia: results of a phase II trial

David E. Spaner, Guizhei Wang, Lindsay McCaw, Yanmei Li, Patricia Disperati, Mary-Ann Cussen, Yonghong Shi

https://doi.org/10.3324/haematol.2015.135418

Safety and efficacy of lenalidomide in combination with rituximab in recurrent indolent non-follicular lymphoma: final results of a phase II study conducted by the Fondazione Italiana Linfomi

Stefano Sacchi, Raffaella Marcheselli, Alessia Bari, Gabriele Buda, Anna Lia Molinari, Luca Baldini, Daniele Vallisa, Marina Cesaretti, Pellegrino Musto, Sonia Ronconi, Giorgina Specchia, Franco Silvestris, Luciano Guardigni, Angela Ferrari, Annalisa Chiapella, Angelo Michele Carella, Armando Santoro, Francesco Di Raimondo, Luigi Marcheselli, Samantha Pozzi

https://doi.org/10.3324/haematol.2015.139329

Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation

Brian G. Engelhardt, Sophie Paczesny, Dae Kwang Jung, Etienne Daguindau, Madan Jagasia, Bipin N. Savani, Wichai Chinratanalab, Robert F. Cornell, Stacey Goodman, John P. Greer, Adetola A. Kassim, Salyka Sengsayadeth, Sandra M. Yoder, Michael T. Rock, James E. Crowe

https://doi.org/10.3324/haematol.2015.139501

Natural killer cell licensing after double cord blood transplantation is driven by the self-HLA class I molecules from the dominant cord blood

Nicolas Guillaume, Pascale Loiseau, Katia Gagne, Hélène Moins-Teissserenc, Jean-Michel Cayuela, Guylaine Henry, Marie Robin, Régis Peffault de Latour, Eliane Gluckman, Gérard Socié, Christelle Retiere, Nicolas Dulphy, Antoine Toubert

https://doi.org/10.3324/haematol.2015.138883