Vol. 101 No. 5 (2016): May, 2016

Next generation research and therapy in red blood cell diseases (710 Online Views)

Roberta Russo, Immacolata Andolfo, Achille Iolascon

https://doi.org/10.3324/haematol.2015.139238

Innovations in treatment and response evaluation in multiple myeloma (784 Online Views)

Ruth Wester, Pieter Sonneveld

https://doi.org/10.3324/haematol.2016.142737

Nonmyeloablative allogeneic hematopoietic cell transplantation (2419 Online Views)

Rainer Storb, Brenda M. Sandmaier

https://doi.org/10.3324/haematol.2015.132860

Role of the tumor microenvironment in mature B-cell lymphoid malignancies (4618 Online Views)

Nathan H. Fowler, Chan Yoon Cheah, Randy D. Gascoyne, John Gribben, Sattva S. Neelapu, Paolo Ghia, Catherine Bollard, Stephen Ansell, Michael Curran, Wyndham H. Wilson, Susan O’Brien, Cliona Grant, Richard Little, Thorsten Zenz, Loretta J. Nastoupil, Kieron Dunleavy

https://doi.org/10.3324/haematol.2015.139493

Chronic myeloid leukemia: reminiscences and dreams (11144 Online Views)

Tariq I. Mughal, Jerald P. Radich, Michael W. Deininger, Jane F. Apperley, Timothy P. Hughes, Christine J. Harrison, Carlo Gambacorti-Passerini, Giuseppe Saglio, Jorge Cortes, George Q. Daley

https://doi.org/10.3324/haematol.2015.139337

ATP11C is a major flippase in human erythrocytes and its defect causes congenital hemolytic anemia (2365 Online Views)

Nobuto Arashiki, Yuichi Takakuwa, Narla Mohandas, John Hale, Kenichi Yoshida, Hiromi Ogura, Taiju Utsugisawa, Shouichi Ohga, Satoru Miyano, Seishi Ogawa, Seiji Kojima, Hitoshi Kanno

https://doi.org/10.3324/haematol.2016.142273

Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation (2743 Online Views)

Lucile Vincent, Derek Vang, Julia Nguyen, Barbara Benson, Jianxun Lei, Kalpna Gupta

https://doi.org/10.3324/haematol.2015.136523

Metabolic pathways that correlate with post-transfusion circulation of stored murine red blood cells (1641 Online Views)

Karen de Wolski, Xiaoyoun Fu, Larry J. Dumont, John D. Roback, Hayley Waterman, Katherine Odem-Davis, Heather L. Howie, James C. Zimring

https://doi.org/10.3324/haematol.2015.139139

Impaired killing of Candida albicans by granulocytes mobilized for transfusion purposes: a role for granule components (1390 Online Views)

Roel P. Gazendam, Annemarie van de Geer, John L. van Hamme, Anton T.J. Tool, Dieke J. van Rees, Cathelijn E.M. Aarts, Maartje van den Biggelaar, Floris van Alphen, Paul Verkuijlen, Alexander B. Meijer, Hans Janssen, Dirk Roos, Timo K. van den Berg, Taco W. Kuijpers

https://doi.org/10.3324/haematol.2015.136630

Long-term serial xenotransplantation of juvenile myelomonocytic leukemia recapitulates human disease in Rag2−/−γc−/− mice (1503 Online Views)

Christopher Felix Krombholz, Konrad Aumann, Matthias Kollek, Daniela Bertele, Silvia Fluhr, Mirjam Kunze, Charlotte M. Niemeyer, Christian Flotho, Miriam Erlacher

https://doi.org/10.3324/haematol.2015.138545

Association of acute myeloid leukemia’s most immature phenotype with risk groups and outcomes (1164 Online Views)

Jonathan M. Gerber, Joshua F. Zeidner, Sarah Morse, Amanda L. Blackford, Brandy Perkins, Breann Yanagisawa, Hao Zhang, Laura Morsberger, Judith Karp, Yi Ning, Christopher D. Gocke, Gary L. Rosner, B. Douglas Smith, Richard J. Jones

https://doi.org/10.3324/haematol.2015.135194

Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma (4045 Online Views)

Esther Drent, Richard W.J. Groen, Willy A. Noort, Maria Themeli, Jeroen J. Lammerts van Bueren, Paul W.H.I. Parren, Jürgen Kuball, Zsolt Sebestyen, Huipin Yuan, Joost de Bruijn, Niels W.C.J. van de Donk, Anton C.M. Martens, Henk M. Lokhorst, Tuna Mutis

https://doi.org/10.3324/haematol.2015.137620

Effects of anti-NKG2A antibody administration on leukemia and normal hematopoietic cells (2951 Online Views)

Loredana Ruggeri, Elena Urbani, Pascale André, Antonella Mancusi, Antonella Tosti, Fabiana Topini, Mathieu Bléry, Lucia Animobono, François Romagné, Nicolai Wagtmann, Andrea Velardi

https://doi.org/10.3324/haematol.2015.135301

Reduced intensity haplo plus single cord transplant compared to double cord transplant: improved engraftment and graft-versus-host disease-free, relapse-free survival (1310 Online Views)

Koen van Besien, Parameswaran Hari, Mei-Jie Zhang, Hong-Tao Liu, Wendy Stock, Lucy Godley, Olatoyosi Odenike, Richard Larson, Michael Bishop, Amittha Wickrema, Usama Gergis, Sebastian Mayer, Tsiporah Shore, Stephanie Tsai, Joanna Rhodes, Melissa M. Cushing, Sandra Korman, Andrew Artz

https://doi.org/10.3324/haematol.2015.138594

Allogeneic unrelated bone marrow transplantation from older donors results in worse prognosis in recipients with aplastic anemia (1032 Online Views)

Yasuyuki Arai, Tadakazu Kondo, Hirohito Yamazaki, Katsuto Takenaka, Junichi Sugita, Takeshi Kobayashi, Yukiyasu Ozawa, Naoyuki Uchida, Koji Iwato, Naoki Kobayashi, Yoshiyuki Takahashi, Ken Ishiyama, Takahiro Fukuda, Tatsuo Ichinohe, Yoshiko Atsuta, Takehiko Mori, Takanori Teshima

https://doi.org/10.3324/haematol.2015.139469

Using zebrafish to model erythroid lineage toxicity and regeneration (1616 Online Views)

Anna Lenard, Elisa Alghisi, Hamina Daff, Massimiliano Donzelli, Claudia McGinnis, Claudia Lengerke

https://doi.org/10.3324/haematol.2016.142562

ε-globin expression is regulated by SUV4-20h1 (982 Online Views)

Yadong Wang, Gerhard Rank, Zhuchen Li, Ying Wang, Junyi Ju, Alexander Nuber, Yupeng Wu, Ming Liu, Min Nie, Feifei Huang, Loretta Cerruti, Chi Ma, Renxiang Tan, Gunnar Schotta, Stephen M. Jane, Changjiang K. Zeng, Quan Zhao

https://doi.org/10.3324/haematol.2015.139980

Anti-hemojuvelin antibody corrects anemia caused by inappropriately high hepcidin levels (1708 Online Views)

Suzana Kovac, Preethne Böser, Yifang Cui, Dunja Ferring-Appel, Daniela Casarrubea, Lili Huang, Emma Fung, Andreas Popp, Bernhard K. Mueller, Matthias W. Hentze

https://doi.org/10.3324/haematol.2015.140772

Impaired formation of erythroblastic islands is associated with erythroid failure and poor prognosis in a significant proportion of patients with myelodysplastic syndromes (1228 Online Views)

Guntram Buesche, Huesniye Teoman, Aristoteles Giagounidis, Gudrun Göhring, Brigitte Schlegelberger, Arnold Ganser, Carlo Aul, Hans-Heinrich Kreipe

https://doi.org/10.3324/haematol.2015.129015

Pegylated interferon alpha-2a for essential thrombocythemia during pregnancy: outcome and safety. A case series (2673 Online Views)

Yan Beauverd, Deepti Radia, Catherine Cargo, Steve Knapper, Mark Drummond, Arvind Pillai, Claire Harrison, Susan Robinson

https://doi.org/10.3324/haematol.2015.139691

Acute myeloid leukemia patients’ clinical response to idasanutlin (RG7388) is associated with pre-treatment MDM2 protein expression in leukemic blasts (1385 Online Views)

Bernhard Reis, Lori Jukofsky, Gong Chen, Giovanni Martinelli, Hua Zhong, W. Venus So, Michael J. Dickinson, Mark Drummond, Sarit Assouline, Maneja Hashemyan, Michel Theron, Steven Blotner, Je-Hwan Lee, Margaret Kasner, Sung-Soo Yoon, Ruediger Rueger, Karen Seiter, Steven A. Middleton, Kevin R. Kelly, Norbert Vey, Karen Yee, Gwen Nichols, Lin-Chi Chen, William E. Pierceall

https://doi.org/10.3324/haematol.2015.139717

Structural modeling of JAK1 mutations in T-cell acute lymphoblastic leukemia reveals a second contact site between pseudokinase and kinase domains (810 Online Views)

Kirsten Canté-Barrett, Joost C.M. Uitdehaag, Jules P.P. Meijerink

https://doi.org/10.3324/haematol.2015.138248

Activity of the Janus kinase inhibitor ruxolitinib in chronic lymphocytic leukemia: results of a phase II trial (1054 Online Views)

David E. Spaner, Guizhei Wang, Lindsay McCaw, Yanmei Li, Patricia Disperati, Mary-Ann Cussen, Yonghong Shi

https://doi.org/10.3324/haematol.2015.135418

Safety and efficacy of lenalidomide in combination with rituximab in recurrent indolent non-follicular lymphoma: final results of a phase II study conducted by the Fondazione Italiana Linfomi (1376 Online Views)

Stefano Sacchi, Raffaella Marcheselli, Alessia Bari, Gabriele Buda, Anna Lia Molinari, Luca Baldini, Daniele Vallisa, Marina Cesaretti, Pellegrino Musto, Sonia Ronconi, Giorgina Specchia, Franco Silvestris, Luciano Guardigni, Angela Ferrari, Annalisa Chiapella, Angelo Michele Carella, Armando Santoro, Francesco Di Raimondo, Luigi Marcheselli, Samantha Pozzi

https://doi.org/10.3324/haematol.2015.139329

Identification of a novel stereotypic IGHV4-59/IGHJ5-encoded B-cell receptor subset expressed by various B-cell lymphomas with high affinity rheumatoid factor activity (732 Online Views)

Richard J. Bende, Jerry Janssen, Thera A.M. Wormhoudt, Koen Wagner, Jeroen E.J. Guikema, Carel J.M. van Noesel

https://doi.org/10.3324/haematol.2015.139626

Early Th1 immunity promotes immune tolerance and may impair graft-versus-leukemia effect after allogeneic hematopoietic cell transplantation (1289 Online Views)

Brian G. Engelhardt, Sophie Paczesny, Dae Kwang Jung, Etienne Daguindau, Madan Jagasia, Bipin N. Savani, Wichai Chinratanalab, Robert F. Cornell, Stacey Goodman, John P. Greer, Adetola A. Kassim, Salyka Sengsayadeth, Sandra M. Yoder, Michael T. Rock, James E. Crowe

https://doi.org/10.3324/haematol.2015.139501

Natural killer cell licensing after double cord blood transplantation is driven by the self-HLA class I molecules from the dominant cord blood (605 Online Views)

Nicolas Guillaume, Pascale Loiseau, Katia Gagne, Hélène Moins-Teissserenc, Jean-Michel Cayuela, Guylaine Henry, Marie Robin, Régis Peffault de Latour, Eliane Gluckman, Gérard Socié, Christelle Retiere, Nicolas Dulphy, Antoine Toubert

https://doi.org/10.3324/haematol.2015.138883