February, 2015
No. 100 (2)

Editorials

Review Articles

Articles

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

Stijn Vanhee, Katrien De Mulder, Yasmine Van Caeneghem, Greet Verstichel, Nadine Van Roy, Björn Menten, Imke Velghe, Jan Philippé, Dominique De Bleser, Bart N. Lambrecht, Tom Taghon, Georges Leclercq, Tessa Kerre, Bart Vandekerckhove

https://doi.org/10.3324/haematol.2014.112144

A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis

Patrick Gutschow, Paul J. Schmidt, Huiling Han, Vaughn Ostland, Thomas B. Bartnikas, Michael A. Pettiglio, Carolina Herrera, James S. Butler, Elizabeta Nemeth, Tomas Ganz, Mark D. Fleming, Mark Westerman

https://doi.org/10.3324/haematol.2014.116723

Dexamethasone targeted directly to macrophages induces macrophage niches that promote erythroid expansion

Mario Falchi, Lilian Varricchio, Fabrizio Martelli, Francesca Masiello, Giulia Federici, Maria Zingariello, Gabriella Girelli, Carolyn Whitsett, Emanuel F. Petricoin, Søren Kragh Moestrup, Ann Zeuner, Anna Rita Migliaccio

https://doi.org/10.3324/haematol.2014.114405

Recurrence risk after anticoagulant treatment of limited duration for late, second venous thromboembolism

Tom van der Hulle, Melanie Tan, Paul L. den Exter, Mark J.G. van Roosmalen, Felix J.M. van der Meer, Jeroen Eikenboom, Menno V. Huisman, Frederikus A. Klok

https://doi.org/10.3324/haematol.2014.112896

Validation of cytogenetic risk groups according to International Prognostic Scoring Systems by peripheral blood CD34+FISH: results from a German diagnostic study in comparison with an international control group

Friederike Braulke, Uwe Platzbecker, Catharina Müller-Thomas, Katharina Götze, Ulrich Germing, Tim H. Brümmendorf, Florian Nolte, Wolf-Karsten Hofmann, Aristoteles A. N. Giagounidis, Michael Lübbert, Peter L. Greenberg, John M. Bennett, Francesc Solé, Mar Mallo, Marilyn L. Slovak, Kazuma Ohyashiki, Michelle M. Le Beau, Heinz Tüchler, Michael Pfeilstöcker, Thomas Nösslinger, Barbara Hildebrandt, Katayoon Shirneshan, Carlo Aul, Reinhard Stauder, Wolfgang R. Sperr, Peter Valent, Christa Fonatsch, Lorenz Trümper, Detlef Haase, Julie Schanz

https://doi.org/10.3324/haematol.2014.110452

Characterization of gene mutations and copy number changes in acute myeloid leukemia using a rapid target enrichment protocol

Niccolò Bolli, Nicla Manes, Thomas McKerrell, Jianxiang Chi, Naomi Park, Gunes Gundem, Michael A. Quail, Vijitha Sathiaseelan, Bram Herman, Charles Crawley, Jenny I. O. Craig, Natalie Conte, Carolyn Grove, Elli Papaemmanuil, Peter J. Campbell, Ignacio Varela, Paul Costeas, George S. Vassiliou

https://doi.org/10.3324/haematol.2014.113381

In vivo and in vitro sensitivity of blastic plasmacytoid dendritic cell neoplasm to SL-401, an interleukin-3 receptor targeted biologic agent

Fanny Angelot-Delettre, Anne Roggy, Arthur E. Frankel, Baptiste Lamarthee, Estelle Seilles, Sabeha Biichle, Bernard Royer, Eric Deconinck, Eric K. Rowinsky, Christopher Brooks, Valerie Bardet, Blandine Benet, Hind Bennani, Zehaira Benseddik, Agathe Debliquis, Daniel Lusina, Mikael Roussel, Françoise Solly, Michel Ticchioni, Philippe Saas, Francine Garnache-Ottou

https://doi.org/10.3324/haematol.2014.111740

A phase 1b/2 study of vosaroxin in combination with cytarabine in patients with relapsed or refractory acute myeloid leukemia

Jeffrey E. Lancet, Gail J. Roboz, Larry D. Cripe, Glenn C. Michelson, Judith A. Fox, Richard D. Leavitt, Tianling Chen, Rachael Hawtin, Adam R. Craig, Farhad Ravandi, Michael B. Maris, Robert K. Stuart, Judith E. Karp

https://doi.org/10.3324/haematol.2014.114769

Prognostic influence of macrophages in patients with diffuse large B-cell lymphoma: a correlative study from a Nordic phase II trial

Sari Riihijärvi, Idun Fiskvik, Minna Taskinen, Heli Vajavaara, Maria Tikkala, Olav Yri, Marja-Liisa Karjalainen-Lindsberg, Jan Delabie, Erlend Smeland, Harald Holte, Sirpa Leppä

https://doi.org/10.3324/haematol.2014.113472

The NOTCH pathway is recurrently mutated in diffuse large B-cell lymphoma associated with hepatitis C virus infection

Luca Arcaini, Davide Rossi, Marco Lucioni, Marta Nicola, Alessio Bruscaggin, Valeria Fiaccadori, Roberta Riboni, Antonio Ramponi, Virginia V. Ferretti, Stefania Cresta, Gloria Margiotta Casaluci, Maurizio Bonfichi, Manuel Gotti, Michele Merli, Aldo Maffi, Mariarosa Arra, Marzia Varettoni, Sara Rattotti, Lucia Morello, Maria Luisa Guerrera, Roberta Sciarra, Gianluca Gaidano, Mario Cazzola, Marco Paulli

https://doi.org/10.3324/haematol.2014.116855

Lenalidomide interferes with tumor-promoting properties of nurse-like cells in chronic lymphocytic leukemia

Stefania Fiorcari, Silvia Martinelli, Jenny Bulgarelli, Valentina Audrito, Patrizia Zucchini, Elisabetta Colaci, Leonardo Potenza, Franco Narni, Mario Luppi, Silvia Deaglio, Roberto Marasca, Rossana Maffei

https://doi.org/10.3324/haematol.2014.113217

Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide

Inger S. Nijhof, Jeroen J. Lammerts van Bueren, Berris van Kessel, Pascale Andre, Yannis Morel, Henk M. Lokhorst, Niels W.C.J. van de Donk, Paul W.H.I. Parren, Tuna Mutis

https://doi.org/10.3324/haematol.2014.117531

Low non-relapse mortality and long-term preserved quality of life in older patients undergoing matched related donor allogeneic stem cell transplantation: a prospective multicenter phase II trial

Didier Blaise, Raynier Devillier, Anne-Gaëlle Lecoroller-Sorriano, Jean-Marie Boher, Agnès Boyer-Chammard, Reza Tabrizi, Patrice Chevallier, Nathalie Fegueux, Anne Sirvent, Mauricette Michallet, Jacques-Olivier Bay, Sabine Fürst, Jean El-Cheikh, Laure Vincent, Thierry Guillaume, Caroline Regny, Noël Milpied, Luca Castagna, Mohamad Mohty

https://doi.org/10.3324/haematol.2014.113571

Cyclosporine and methotrexate-related pharmacogenomic predictors of acute graft-versus-host disease

Isabelle Laverdière, Chantal Guillemette, Ryad Tamouza, Pascale Loiseau, Regis Peffault de Latour, Marie Robin, Félix Couture, Alain Filion, Marc Lalancette, Alan Tourancheau, Dominique Charron, Gérard Socié, Éric Lévesque

https://doi.org/10.3324/haematol.2014.109884

Pre-chemotherapy risk factors for invasive fungal diseases: prospective analysis of 1,192 patients with newly diagnosed acute myeloid leukemia (SEIFEM 2010-a multicenter study)

Morena Caira, Anna Candoni, Luisa Verga, Alessandro Busca, Mario Delia, Annamaria Nosari, Cecilia Caramatti, Carlo Castagnola, Chiara Cattaneo, Rosa Fanci, Anna Chierichini, Lorella Melillo, Maria Enza Mitra, Marco Picardi, Leonardo Potenza, Prassede Salutari, Nicola Vianelli, Luca Facchini, Monica Cesarini, Maria Rosaria De Paolis, Roberta Di Blasi, Francesca Farina, Adriano Venditti, Antonella Ferrari, Mariagrazia Garzia, Cristina Gasbarrino, Rosangela Invernizzi, Federica Lessi, Annunziata Manna, Bruno Martino, Gianpaolo Nadali, Massimo Offidani, Laura Paris, Vincenzo Pavone, Giuseppe Rossi, Antonio Spadea, Giorgina Specchia, Enrico Maria Trecarichi, Adriana Vacca, Simone Cesaro, Vincenzo Perriello, Franco Aversa, Mario Tumbarello, Livio Pagano

https://doi.org/10.3324/haematol.2014.113399

Online Only Articles

JAK2, CALR, and MPL mutation spectrum in Japanese patients with myeloproliferative neoplasms

Shuichi Shirane, Marito Araki, Soji Morishita, Yoko Edahiro, Hiraku Takei, Yongjin Yoo, Murim Choi, Yoshitaka Sunami, Yumi Hironaka, Masaaki Noguchi, Michiaki Koike, Naohiro Noda, Akimichi Ohsaka, Norio Komatsu

https://doi.org/10.3324/haematol.2014.115113

Pharmacological targeting of β-catenin in normal karyotype acute myeloid leukemia blasts

Elizabeth A. Griffiths, Michelle C. Golding, Pragya Srivastava, Benjamin J. Povinelli, Smitha R. James, Laurie A. Ford, Meir Wetzler, Eunice S. Wang, Michael J. Nemeth

https://doi.org/10.3324/haematol.2014.113118

The prognostic value of multiparameter flow cytometry minimal residual disease assessment in relapsed multiple myeloma

Bruno Paiva, Mauricio Chandia, Noemi Puig, Maria-Belen Vidriales, Jose J. Perez, Lucia Lopez-Corral, Enrique M. Ocio, Ramon Garcia-Sanz, Norma C. Gutierrez, Ana Jimenez-Ubieto, Juan-José Lahuerta, Maria-Victoria Mateos, Jesús F. San Miguel

https://doi.org/10.3324/haematol.2014.115162

Phase II study of bendamustine, bortezomib and dexamethasone as second-line treatment for elderly patients with multiple myeloma: the Intergroupe Francophone du Myelome 2009-01 trial

Philippe Rodon, Cyrille Hulin, Brigitte Pegourie, Mourad Tiab, Bruno Anglaret, Lotfi Benboubker, Henry Jardel, Olivier Decaux, Brigitte Kolb, Murielle Roussel, Laurent Garderet, Xavier Leleu, Olivier Fitoussi, Carine Chaleteix, Philippe Casassus, Pascal Lenain, Bruno Royer, Anne Banos, Riad Benramdane, Pascale Cony-Makhoul, Mamoun Dib, Jean Fontan, Anne-Marie Stoppa, Catherine Traullé, Jean-Pierre Vilque, Marie-Odile Pétillon, Claire Mathiot, Thomas Dejoie, Hervé Avet-Loiseau, Philippe Moreau

https://doi.org/10.3324/haematol.2014.110890

A rare case of IGH/MYC and IGH/BCL2 double hit primary plasma cell leukemia

Anna Kalff, Tiffany Khong, Meaghan Wall, Malgorzata Gorniak, Sridurga Mithraprabhu, Lynda J. Campbell, Andrew Spencer

https://doi.org/10.3324/haematol.2014.111385

Health-related quality of life from the MM-003 trial of pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed and/or refractory multiple myeloma

Kevin W. Song, Meletios A. Dimopoulos, Katja C. Weisel, Philippe Moreau, Antonio Palumbo, Andrew Belch, Stephen Schey, Pieter Sonneveld, Lars Sternas, Xin Yu, Ramesh Amatya, Mara S. Monzini, Mohamed Zaki, Christian Jacques, Jesus San Miguel

https://doi.org/10.3324/haematol.2014.112557

Oral administration of a bone morphogenetic protein type I receptor inhibitor prevents the development of anemia of inflammation

Claire Mayeur, Starsha A. Kolodziej, Amy Wang, Xin Xu, Arthur Lee, Paul B. Yu, John Shen, Kenneth D. Bloch, Donald B. Bloch

https://doi.org/10.3324/haematol.2014.111484

Extending the clinical and immunological phenotype of human interleukin-21 receptor deficiency

Polina Stepensky, Baerbel Keller, Omar Abuzaitoun, Avraham Shaag, Barak Yaacov, Susanne Unger, Maximilian Seidl, Marta Rizzi, Michael Weintraub, Orly Elpeleg, Klaus Warnatz

https://doi.org/10.3324/haematol.2014.112508