June, 2014
No. 99 (6)

Editorials

Editorials & Perspectives

A Master Class for European Hematology

Cheng Hock Toh, Janet Strivens, Margarita Guenova, Szabolcs Modok

https://doi.org/10.3324/haematol.2014.107540

Review Articles

Articles

Lactotransferrin-Cre reporter mice trace neutrophils, monocytes/macrophages and distinct subtypes of dendritic cells

Boris Kovacic, Andrea Hoelbl-Kovacic, Katrin M. Fischhuber, Nicole R. Leitner, Dagmar Gotthardt, Emilio Casanova, Veronika Sexl, Mathias Müller

https://doi.org/10.3324/haematol.2013.097154

The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice

Antonella Nai, Rosa M. Pellegrino, Marco Rausa, Alessia Pagani, Martina Boero, Laura Silvestri, Giuseppe Saglio, Antonella Roetto, Clara Camaschella

https://doi.org/10.3324/haematol.2013.103143

Molecular analysis of Fanconi anemia: the experience of the Bone Marrow Failure Study Group of the Italian Association of Pediatric Onco-Hematology

Daniela De Rocco, Roberta Bottega, Enrico Cappelli, Simona Cavani, Maria Criscuolo, Elena Nicchia, Fabio Corsolini, Chiara Greco, Adriana Borriello, Johanna Svahn, Marta Pillon, Cristina Mecucci, Gabriella Casazza, Federico Verzegnassi, Chiara Cugno, Anna Locasciulli, Piero Farruggia, Daniela Longoni, Ugo Ramenghi, Walter Barberi, Fabio Tucci, Silverio Perrotta, Paola Grammatico, Helmut Hanenberg, Fulvio Della Ragione, Carlo Dufour, Anna Savoia

https://doi.org/10.3324/haematol.2014.104224

Knockdown of Hnrnpa0, a del(5q) gene, alters myeloid cell fate in murine cells through regulation of AU-rich transcripts

David J. Young, Angela Stoddart, Joy Nakitandwe, Shann-Ching Chen, Zhijian Qian, James R. Downing, Michelle M. Le Beau

https://doi.org/10.3324/haematol.2013.098657

p53 protein expression independently predicts outcome in patients with lower-risk myelodysplastic syndromes with del(5q)

Leonie Saft, Mohsen Karimi, Mehran Ghaderi, András Matolcsy, Ghulam J. Mufti, Austin Kulasekararaj, Gudrun Göhring, Aristoteles Giagounidis, Dominik Selleslag, Petra Muus, Guillermo Sanz, Moshe Mittelman, David Bowen, Anna Porwit, Tommy Fu, Jay Backstrom, Pierre Fenaux, Kyle J. MacBeth, Eva Hellström-Lindberg

https://doi.org/10.3324/haematol.2013.098103

Attenuated measles virus controls pediatric acute B-lineage lymphoblastic leukemia in NOD/SCID mice

Nike C. Lühl, Felix Zirngibl, Carmen Dorneburg, Jiwu Wei, Meike Dahlhaus, Thomas F.E. Barth, Lüder H. Meyer, Manon Queudeville, Sarah Eckhoff, Klaus-Michael Debatin, Christian Beltinger

https://doi.org/10.3324/haematol.2013.087205

Adult B-cell acute lymphoblastic leukemia cells display decreased PTEN activity and constitutive hyperactivation of PI3K/Akt pathway despite high PTEN protein levels

A. Margarida Gomes, Maria V. D. Soares, Patrícia Ribeiro, Joana Caldas, Vanda Póvoa, Leila R. Martins, Alice Melão, Ana Serra-Caetano, Aida B. de Sousa, João F. Lacerda, João T. Barata

https://doi.org/10.3324/haematol.2013.096438

Cortactin, another player in the Lyn signaling pathway, is over-expressed and alternatively spliced in leukemic cells from patients with B-cell chronic lymphocytic leukemia

Cristina Gattazzo, Veronica Martini, Federica Frezzato, Valentina Trimarco, Elena Tibaldi, Monica Castelli, Monica Facco, Francesca Zonta, Anna Maria Brunati, Renato Zambello, Gianpietro Semenzato, Livio Trentin

https://doi.org/10.3324/haematol.2013.090183

Chronic lymphocytic leukemia nurse-like cells express hepatocyte growth factor receptor (c-MET) and indoleamine 2,3-dioxygenase and display features of immunosuppressive type 2 skewed macrophages

Paolo Giannoni, Gabriella Pietra, Giorgia Travaini, Rodolfo Quarto, Genti Shyti, Roberto Benelli, Laura Ottaggio, Maria Cristina Mingari, Simona Zupo, Giovanna Cutrona, Ivana Pierri, Enrico Balleari, Alessandra Pattarozzi, Marco Calvaruso, Claudio Tripodo, Manlio Ferrarini, Daniela de Totero

https://doi.org/10.3324/haematol.2013.091405

Interactions between comorbidity and treatment of chronic lymphocytic leukemia: results of German Chronic Lymphocytic Leukemia Study Group trials

Valentin Goede, Paula Cramer, Raymonde Busch, Manuela Bergmann, Martina Stauch, Georg Hopfinger, Stephan Stilgenbauer, Hartmut Döhner, Anne Westermann, Clemens M. Wendtner, Barbara Eichhorst, Michael Hallek

https://doi.org/10.3324/haematol.2013.096792

The predictive role of interim positron emission tomography for Hodgkin lymphoma treatment outcome is confirmed using the interpretation criteria of the Deauville five-point scale

Andrea Gallamini, Sally F. Barrington, Alberto Biggi, Stephane Chauvie, Lale Kostakoglu, Michele Gregianin, Michel Meignan, George N. Mikhaeel, Annika Loft, Jan M. Zaucha, John F. Seymour, Michael S. Hofman, Luigi Rigacci, Alessandro Pulsoni, Morton Coleman, Eldad J. Dann, Livio Trentin, Olivier Casasnovas, Chiara Rusconi, Pauline Brice, Silvia Bolis, Simonetta Viviani, Flavia Salvi, Stefano Luminari, Martin Hutchings

https://doi.org/10.3324/haematol.2013.103218

Bortezomib cumulative dose, efficacy, and tolerability with three different bortezomib-melphalan-prednisone regimens in previously untreated myeloma patients ineligible for high-dose therapy

María-Victoria Mateos, Sara Bringhen, Paul G. Richardson, Juan Jose Lahuerta, Alessandra Larocca, Albert Oriol, Mario Boccadoro, Ramón García-Sanz, Francesco Di Raimondo, Dixie-Lee Esseltine, Helgi van de Velde, Avinash Desai, Anil Londhe, Jesús F. San Miguel, Antonio Palumbo

https://doi.org/10.3324/haematol.2013.099341

MicroRNA-23a mediates post-transcriptional regulation of CXCL12 in bone marrow stromal cells

Laleh S. Arabanian, Fernando A. Fierro, Friedrich Stölzel, Carolin Heder, David M. Poitz, Ruth H. Strasser, Manja Wobus, Martin Borhäuser, Ruben A. Ferrer, Uwe Platzbecker, Matthias Schieker, Denitsa Docheva, Gerhard Ehninger, Thomas Illmer

https://doi.org/10.3324/haematol.2013.097675

Guidelines

The clinical relevance and management of monoclonal gammopathy of undetermined significance and related disorders: recommendations from the European Myeloma Network

Niels W.C.J. van de Donk, Antonio Palumbo, Hans Erik Johnsen, Monika Engelhardt, Francesca Gay, Henrik Gregersen, Roman Hajek, Martina Kleber, Heinz Ludwig, Gareth Morgan, Pellegrino Musto, Torben Plesner, Orhan Sezer, Evangelos Terpos, Anders Waage, Sonja Zweegman, Hermann Einsele, Pieter Sonneveld, Henk M. Lokhorst

https://doi.org/10.3324/haematol.2013.100552

Online Only Articles

Imatinib and ruxolitinib association: first experience in two patients

Alessandra Iurlo, Umberto Gianelli, Davide Rapezzi, Daniele Cattaneo, Elisa Fermo, Francesca Binda, Elisa Santambrogio, Cristina Bucelli, Agostino Cortelezzi

https://doi.org/10.3324/haematol.2013.102525

Markedly elevated serum total N-terminal propeptide of type I collagen is a novel marker for the diagnosis and follow up of patients with POEMS syndrome

Chen Wang, Ying-Lei Zhou, Hao Cai, Xin-Qi Cheng, Wei Zhang, Wen-Ying Kang, Xu-Zhen Qin, Ming-Hui Duan, Hui-Juan Han, Xin-Xin Cao, Dao-Bin Zhou, Jian Li

https://doi.org/10.3324/haematol.2013.102962

A phase II trial of pan-KIR2D blockade with IPH2101 in smoldering multiple myeloma

Neha Korde, Mattias Carlsten, Min-Jung Lee, Alex Minter, Esther Tan, Mary Kwok, Elisabet Manasanch, Manisha Bhutani, Nishant Tageja, Mark Roschewski, Adriana Zingone, Rene Costello, Marcia Mulquin, Diamond Zuchlinski, Irina Maric, Katherine R. Calvo, Raul Braylan, Prashant Tembhare, Constance Yuan, Maryalice Stetler-Stevenson, Jane Trepel, Richard Childs, Ola Landgren

https://doi.org/10.3324/haematol.2013.103085

The importance of harmonizing interim positron emission tomography in non-Hodgkin lymphoma: focus on the Deauville criteria

Elske Quak, Narinée Hovhannisyan, Charline Lasnon, Christophe Fruchart, Jean-Pierre Vilque, Dada Musafiri, Nicolas Aide

https://doi.org/10.3324/haematol.2014.104125

Proinflammatory human 6-sulfo LacNAc-positive dendritic cells accumulate in intestinal acute graft-versus-host disease

Ulrich Sommer, Brit Larsson, Sebastian Tuve, Rebekka Wehner, Nick Zimmermann, Michael Kramer, Anja Kloβ, Claudia Günther, Jana Babatz, Renate Schmelz, Stefan Brückner, Johannes Schetelig, Martin Bornhäuser, Knut Schäkel, Michael Philipp Bachmann, Daniela Aust, Gustavo Baretton, Marc Schmitz

https://doi.org/10.3324/haematol.2013.101071

Clinically relevant doses of FLT3-kinase inhibitors quizartinib and midostaurin do not impair T-cell reactivity and function

Denise Wolleschak, Thomas S. Mack, Florian Perner, Stephanie Frey, Tina M. Schnöder, Marie-Christine Wagner, Christine Höding, Marina C. Pils, Andreas Parkner, Stefanie Kliche, Burkhart Schraven, Katrin Hebel, Monika Brunner-Weinzierl, Satish Ranjan, Berend Isermann, Daniel B. Lipka, Thomas Fischer, Florian H. Heidel

https://doi.org/10.3324/haematol.2014.104331

Frequent occurrence of non-malignant genetic alterations in clinical grade mesenchymal stromal cells expanded for cell therapy protocols

Chiara Capelli, Olga Pedrini, Gisella Cassina, Orietta Spinelli, Silvia Salmoiraghi, Josée Golay, Alessandro Rambaldi, Ursula Giussani, Martino Introna

https://doi.org/10.3324/haematol.2014.104711