May, 2014
No. 99 (5)

Editorials

Editorials & Perspectives

Current pre-clinical and clinical advances in the BCR-ABL1-positive and -negative chronic myeloproliferative neoplasms

Tariq I. Mughal, Alessandro M. Vannucchi, Simona Soverini, Alexandra Bazeos, Raoul Tibes, Giuseppe Saglio, Omar Abdel-Wahab, Animesh Pardanani, Rudiger Hehlmann, Tiziano Barbui, Richard Van Etten, Ayalew Tefferi, John M. Goldman

https://doi.org/10.3324/haematol.2013.097832

Review Articles

Nature and importance of follicular lymphoma precursors

Emilie Mamessier, Florence Broussais-Guillaumot, Bruno Chetaille, Reda Bouabdallah, Luc Xerri, Elaine S. Jaffe, Bertrand Nadel

https://doi.org/10.3324/haematol.2013.085548

Articles

Myelodysplastic Syndromes

Complex or monosomal karyotype and not blast percentage is associated with poor survival in acute myeloid leukemia and myelodysplastic syndrome patients with inv(3)(q21q26.2)/t(3;3)(q21;q26.2): a Bone Marrow Pathology Group study

Heesun J. Rogers, James W. Vardiman, John Anastasi, Gordana Raca, Natasha M. Savage, Athena M. Cherry, Daniel Arber, Erika Moore, Jennifer JD. Morrissette, Adam Bagg, Yen-Chun Liu, Susan Mathew, Attilio Orazi, Pei Lin, Sa A. Wang, Carlos E. Bueso-Ramos, Kathryn Foucar, Robert P. Hasserjian, Ramon V. Tiu, Matthew Karafa, Eric D. Hsi

https://doi.org/10.3324/haematol.2013.096420

Myeloproliferative Disorders

SRSF2-p95 hotspot mutation is highly associated with advanced forms of mastocytosis and mutations in epigenetic regulator genes

Katia Hanssens, Fabienne Brenet, Julie Agopian, Sophie Georgin-Lavialle, Gandhi Damaj, Laure Cabaret, Maria Olivia Chandesris, Paulo de Sepulveda, Olivier Hermine, Patrice Dubreuil, Erinn Soucie

https://doi.org/10.3324/haematol.2013.095133

Acute Myeloid Leukemia

Leukemia-induced phenotypic and functional defects in natural killer cells predict failure to achieve remission in acute myeloid leukemia

Kate Stringaris, Takuya Sekine, Ahmad Khoder, Abdullah Alsuliman, Bonnie Razzaghi, Ruhena Sargeant, Jiri Pavlu, Gill Brisley, Hugues de Lavallade, Anushruti Sarvaria, David Marin, Stephan Mielke, Jane F. Apperley, Elizabeth J. Shpall, John Barrett, Katayoun Rezvani

https://doi.org/10.3324/haematol.2013.087536

Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations

Saman Abbas, Mathijs A. Sanders, Annelieke Zeilemaker, Wendy M.C. Geertsma-Kleinekoort, Jasper E. Koenders, Francois G. Kavelaars, Zabiollah G. Abbas, Souad Mahamoud, Isabel W.T. Chu, Remco Hoogenboezem, Justine K. Peeters, Ellen van Drunen, Janneke van Galen, H. Berna Beverloo, Bob Löwenberg, Peter J.M. Valk

https://doi.org/10.3324/haematol.2013.095604

t(6;9)(p22;q34)/DEK-NUP214-rearranged pediatric myeloid leukemia: an international study of 62 patients

Julie Damgaard Sandahl, Eva A. Coenen, Erik Forestier, Jochen Harbott, Bertil Johansson, Gitte Kerndrup, Souichi Adachi, Anne Auvrignon, H. Berna Beverloo, Jean-Michel Cayuela, Lucy Chilton, Maarten Fornerod, Valérie de Haas, Christine J. Harrison, Hiroto Inaba, Gertjan J.L. Kaspers, Der-Cherng Liang, Franco Locatelli, Riccardo Masetti, Christine Perot, Susana C. Raimondi, Katarina Reinhardt, Daisuke Tomizawa, Nils von Neuhoff, Marco Zecca, C. Michel Zwaan, Marry M. van den Heuvel-Eibrink, Henrik Hasle

https://doi.org/10.3324/haematol.2013.098517

Chronic Lymphocytic Leukemia

The prognostic impact of minimal residual disease in patients with chronic lymphocytic leukemia requiring first-line therapy

Rodrigo Santacruz, Neus Villamor, Marta Aymerich, Alejandra Martínez-Trillos, Cristina López, Alba Navarro, María Rozman, Sílvia Beà, Cristina Royo, Maite Cazorla, Dolors Colomer, Eva Giné, Magda Pinyol, Xose S. Puente, Carlos López-Otín, Elías Campo, Armando López-Guillermo, Julio Delgado

https://doi.org/10.3324/haematol.2013.099796

Clinical significance of LAIR1 (CD305) as assessed by flow cytometry in a prospective series of patients with chronic lymphocytic leukemia

Omar Perbellini, Erika Falisi, Ilaria Giaretta, Elisa Boscaro, Elisabetta Novella, Monica Facco, Stefania Fortuna, Silvia Finotto, Eliana Amati, Francesco Maniscalco, Anna Montaldi, Alberta Alghisi, Fiorenza Aprili, Laura Bonaldi, Rossella Paolini, Maria Teresa Scupoli, Livio Trentin, Achille Ambrosetti, Gianpietro Semenzato, Giovanni Pizzolo, Francesco Rodeghiero, Carlo Visco

https://doi.org/10.3324/haematol.2013.096362

HLA-G is a component of the chronic lymphocytic leukemia escape repertoire to generate immune suppression: impact of the HLA-G 14 base pair (rs66554220) polymorphism

Roberta Rizzo, Valentina Audrito, Paola Vacca, Davide Rossi, Davide Brusa, Marina Stignani, Daria Bortolotti, Giovanni D’Arena, Marta Coscia, Luca Laurenti, Francesco Forconi, Gianluca Gaidano, Maria Cristina Mingari, Lorenzo Moretta, Fabio Malavasi, Silvia Deaglio

https://doi.org/10.3324/haematol.2013.095281

Non-Hodgkin Lymphoma

Molecular and cytogenetic characterization of expanded B-cell clones from multiclonal versus monoclonal B-cell chronic lymphoproliferative disorders

Ana Henriques, Arancha Rodríguez-Caballero, Ignacio Criado, Anton W. Langerak, Wendy G. Nieto, Quentin Lécrevisse, Marcos González, Emília Cortesão, Artur Paiva, Julia Almeida, Alberto Orfao

https://doi.org/10.3324/haematol.2013.098913

Stem Cell Transplantation

Use of the quality management system “JACIE” and outcome after hematopoietic stem cell transplantation

Alois Gratwohl, Ronald Brand, Eoin McGrath, Anja van Biezen, Anna Sureda, Per Ljungman, Helen Baldomero, Christian Chabannon, Jane Apperley

https://doi.org/10.3324/haematol.2013.096461

Allogeneic hematopoietic stem cell transplantation in patients with polycythemia vera or essential thrombocythemia transformed to myelofibrosis or acute myeloid leukemia: a report from the MPN Subcommittee of the Chronic Malignancies Working Party of the European Group for Blood and Marrow Transplantation

Federico Lussana, Alessandro Rambaldi, Maria Chiara Finazzi, Anja van Biezen, Marijke Scholten, Elena Oldani, Alessandra Carobbio, Simona Iacobelli, Jurgen Finke, Arnon Nagler, Liisa Volin, Thierry Lamy, Renate Arnold, Mohamad Mohty, Mauricette Michallet, Theo de Witte, Eduardo Olavarria, Nicolaus Kröger

https://doi.org/10.3324/haematol.2013.094284

Baseline characteristics and disease burden in patients in the International Paroxysmal Nocturnal Hemoglobinuria Registry

Hubert Schrezenmeier, Petra Muus, Gérard Socié, Jeffrey Szer, Alvaro Urbano-Ispizua, Jaroslaw P. Maciejewski, Robert A. Brodsky, Monica Bessler, Yuzuru Kanakura, Wendell Rosse, Gus Khursigara, Camille Bedrosian, Peter Hillmen

https://doi.org/10.3324/haematol.2013.093161

Platelet Disorders

Abnormal platelet count is an independent predictor of mortality in the elderly and is influenced by ethnicity

Pavlos Msaouel, Anthony P. Lam, Krishna Gundabolu, Grigorios Chrysofakis, Yiting Yu, Ioannis Mantzaris, Ellen Friedman, Amit Verma

https://doi.org/10.3324/haematol.2013.101949

Guidelines

Hematopoietic stem cell transplantation in thalassemia major and sickle cell disease: indications and management recommendations from an international expert panel

Emanuele Angelucci, Susanne Matthes-Martin, Donatella Baronciani, Françoise Bernaudin, Sonia Bonanomi, Maria Domenica Cappellini, Jean-Hugues Dalle, Paolo Di Bartolomeo, Cristina Díaz de Heredia, Roswitha Dickerhoff, Claudio Giardini, Eliane Gluckman, Ayad Achmed Hussein, Naynesh Kamani, Milen Minkov, Franco Locatelli, Vanderson Rocha, Petr Sedlacek, Frans Smiers, Isabelle Thuret, Isaac Yaniv, Marina Cavazzana, Christina Peters

https://doi.org/10.3324/haematol.2013.099747

Online Only Articles

DDX3X-MLLT10 fusion in adults with NOTCH1 positive T-cell acute lymphoblastic leukemia

Lucia Brandimarte, Roberta La Starza, Valentina Gianfelici, Gianluca Barba, Valentina Pierini, Danika Di Giacomo, Jan Cools, Loredana Elia, Antonella Vitale, Luigiana Luciano, Antonella Bardi, Sabina Chiaretti, Caterina Matteucci, Giorgina Specchia, Cristina Mecucci

https://doi.org/10.3324/haematol.2013.101725

Chemotherapy-induced augmentation of T cells expressing inhibitory receptors is reversed by treatment with lenalidomide in chronic lymphocytic leukemia

Franz J. Gassner, Nadja Zaborsky, Daniel Neureiter, Michael Huemer, Thomas Melchardt, Alexander Egle, Stefan Rebhandl, Kemal Catakovic, Tanja N. Hartmann, Richard Greil, Roland Geisberger

https://doi.org/10.3324/haematol.2013.098459

Hepatitis B or C virus infection and risk of non-Hodgkin lymphoma among solid organ transplant recipients

Lindsay M. Morton, Todd M. Gibson, Christina A. Clarke, Charles F. Lynch, Dennis D. Weisenburger, Eric A. Engels

https://doi.org/10.3324/haematol.2013.101600

Impaired blood rheology plays a role in the chronic disorders associated with sickle cell-hemoglobin C disease

Nathalie Lemonne, Yann Lamarre, Marc Romana, Marie-Dominique Hardy-Dessources, François Lionnet, Xavier Waltz, Vanessa Tarer, Danielle Mougenel, Benoît Tressières, Marie-Laure Lalanne-Mistrih, Maryse Etienne-Julan, Philippe Connes

https://doi.org/10.3324/haematol.2014.104745