December, 2013
No. 98 (12)

Editorials

Articles

Osteoclasts are not crucial for hematopoietic stem cell maintenance in adult mice

Carmen Flores, Ilana Moscatelli, Christian S. Thudium, Natasja Stæhr Gudmann, Jesper S. Thomsen, Annemarie Brüel, Morten A. Karsdal, Kim Henriksen, Johan Richter

https://doi.org/10.3324/haematol.2013.089466

Targeted re-sequencing analysis of 25 genes commonly mutated in myeloid disorders in del(5q) myelodysplastic syndromes

Marta Fernandez-Mercado, Adam Burns, Andrea Pellagatti, Aristoteles Giagounidis, Ulrich Germing, Xabier Agirre, Felipe Prosper, Carlo Aul, Sally Killick, James S. Wainscoat, Anna Schuh, Jacqueline Boultwood

https://doi.org/10.3324/haematol.2013.086686

Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I

Srdan Verstovsek, Ruben A. Mesa, Jason Gotlib, Richard S. Levy, Vikas Gupta, John F. DiPersio, John V. Catalano, Michael W.N. Deininger, Carole B. Miller, Richard T. Silver, Moshe Talpaz, Elliott F. Winton, Jimmie H. Harvey, Murat O. Arcasoy, Elizabeth O. Hexner, Roger M. Lyons, Ronald Paquette, Azra Raza, Kris Vaddi, Susan Erickson-Viitanen, William Sun, Victor Sandor, Hagop M. Kantarjian

https://doi.org/10.3324/haematol.2013.092155

BubR1 is frequently repressed in acute myeloid leukemia and its re-expression sensitizes cells to antimitotic therapy

Dominik Schnerch, Andrea Schmidts, Marie Follo, Josefina Udi, Julia Felthaus, Dietmar Pfeifer, Monika Engelhardt, Ralph Wäsch

https://doi.org/10.3324/haematol.2013.087452

Acute Leukemia

Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors

Denise Niewerth, Niels E. Franke, Gerrit Jansen, Yehuda G. Assaraf, Johan van Meerloo, Christopher J. Kirk, Jeremiah Degenhardt, Janet Anderl, Aaron D. Schimmer, Sonja Zweegman, Valerie de Haas, Terzah M. Horton, Gertjan J.L. Kaspers, Jacqueline Cloos

https://doi.org/10.3324/haematol.2013.092411

The synergism of MCL1 and glycolysis on pediatric acute lymphoblastic leukemia cell survival and prednisolone resistance

Ingrid M. Ariës, Bo R. Hansen, Troels Koch, Rosanna van den Dungen, William E. Evans, Rob Pieters, Monique L. den Boer

https://doi.org/10.3324/haematol.2013.093823

Genome-wide profiling identifies a DNA methylation signature that associates with TET2 mutations in diffuse large B-cell lymphoma

Fazila Asmar, Vasu Punj, Jesper Christensen, Marianne T. Pedersen, Anja Pedersen, Anders B. Nielsen, Christoffer Hother, Ulrik Ralfkiaer, Peter Brown, Elisabeth Ralfkiaer, Kristian Helin, Kirsten Grønbæk

https://doi.org/10.3324/haematol.2013.088740

Dissecting the gray zone between follicular lymphoma and marginal zone lymphoma using morphological and genetic features

Oscar Krijgsman, Patricia Gonzalez, Olga Balagué Ponz, Margaretha G.M. Roemer, Stefanie Slot, Annegien Broeks, Linde Braaf, Ron M. Kerkhoven, Freek Bot, Krijn van Groningen, Max Beijert, Bauke Ylstra, Daphne de Jong

https://doi.org/10.3324/haematol.2013.085118

Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia

Anne Rensing-Ehl, Ales Janda, Myriam R. Lorenz, Beryl P. Gladstone, Ilka Fuchs, Mario Abinun, Michael Albert, Karina Butler, Andrew Cant, Anna-Maria Cseh, Martin Ebinger, Sigune Goldacker, Sophie Hambleton, Holger Hebart, Leonora Houet, Karim Kentouche, Ingrid Kühnle, Kai Lehmberg, Ester Mejstrikova, Charlotte Niemeyer, Milen Minkov, Olaf Neth, Gregor Dückers, Stephan Owens, Joachim Rösler, Freimut H. Schilling, Volker Schuster, Markus G. Seidel, Petr Smisek, Martina Sukova, Peter Svec, Thomas Wiesel, Benjamin Gathmann, Klaus Schwarz, Werner Vach, Stephan Ehl, Carsten Speckmann

https://doi.org/10.3324/haematol.2012.081901

Subsequent donation requests among 2472 unrelated hematopoietic progenitor cell donors are associated with bone marrow harvest

Robert N. Lown, Sameer Tulpule, Nigel H. Russell, Charles F. Craddock, Rochelle Roest, J. Alejandro Madrigal, Bronwen E. Shaw

https://doi.org/10.3324/haematol.2013.088971

Loss of quiescence and impaired function of CD34+/CD38low cells one year following autologous stem cell transplantation

Carolien M. Woolthuis, Annet Z. Brouwers-Vos, Gerwin Huls, Joost Th. M. de Wolf, Jan Jacob Schuringa, Edo Vellenga

https://doi.org/10.3324/haematol.2013.086744

Novel exon 2 α spectrin mutation and intragenic crossover: three morphological phenotypes associated with four distinct α spectrin defects

Sabina Swierczek, Archana M. Agarwal, Kubendran Naidoo, Felipe R. Lorenzo, Jonathan Whisenant, Roberto H. Nussenzveig, Neeraj Agarwal, Theresa L. Coetzer, Josef T. Prchal

https://doi.org/10.3324/haematol.2013.086629

Guidelines

European guidelines for empirical antibacterial therapy for febrile neutropenic patients in the era of growing resistance: summary of the 2011 4th European Conference on Infections in Leukemia

Diana Averbuch, Christina Orasch, Catherine Cordonnier, David M. Livermore, Małgorzata Mikulska, Claudio Viscoli, Inge C. Gyssens, Winfried V. Kern, Galina Klyasova, Oscar Marchetti, Dan Engelhard, Murat Akova

https://doi.org/10.3324/haematol.2013.091025

Targeted therapy against multi-resistant bacteria in leukemic and hematopoietic stem cell transplant recipients: guidelines of the 4th European Conference on Infections in Leukemia (ECIL-4, 2011)

Diana Averbuch, Catherine Cordonnier, David M. Livermore, Małgorzata Mikulska, Christina Orasch, Claudio Viscoli, Inge C. Gyssens, Winfried V. Kern, Galina Klyasova, Oscar Marchetti, Dan Engelhard, Murat Akova

https://doi.org/10.3324/haematol.2013.091330

Online Only Articles

Impact of chemotherapy on venous thromboembolism

Patrizia Ferroni, Silvia Riondino, Fiorella Guadagni, Mario Roselli

https://doi.org/10.3324/haematol.2013.092528

Immunotherapy-based regimen in anti-MAG neuropathy: results in 45 patients

Marie-Anne Hospital, Karine Viala, Sonia Dragomir, Vincent Levy, Fleur Cohen-Aubart, Jean Neil, Lucile Musset, Sylvain Choquet, Jean-Marc Leger, Véronique Leblond

https://doi.org/10.3324/haematol.2013.087213

Mutation spectrum in Chinese patients affected by congenital sideroblastic anemia and a search for a genotype-phenotype relationship

Gang Liu, Shanshan Guo, Huiyuan Kang, Fuming Zhang, Yulin Hu, Lu Wang, Mianyang Li, Yongxin Ru, Clara Camaschella, Bing Han, Guangjun Nie

https://doi.org/10.3324/haematol.2013.095513

FLT3-ITD confers poor prognosis in patients with acute promyelocytic leukemia treated with AIDA protocols: long-term follow-up analysis

Massimo Breccia, Giuseppina Loglisci, Maria Giovanna Loglisci, Roberto Ricci, Daniela Diverio, Roberto Latagliata, Robin Foà, Francesco Lo-Coco

https://doi.org/10.3324/haematol.2013.095380

First description of the t(10;11)(q22;q23)/MLL-TET1 translocation in a T-cell lymphoblastic lymphoma, with subsequent lineage switch to acute myelomonocytic myeloid leukemia

Antoine Ittel, Eric Jeandidier, Catherine Helias, Nathalie Perrusson, Catherine Humbrecht, Bruno Lioure, Isabelle Mazurier, Caroline Mayeur-Rousse, Amandine Lavaux, Sylvie Thiebault, Felix Lerintiu, Carine Gervais, Laurent Mauvieux

https://doi.org/10.3324/haematol.2013.096750

Obituary