January, 2014
No. 99 (1)

Editorials

Review Articles

Articles

High CD45 surface expression determines relapse risk in children with precursor B-cell and T-cell acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol (404 Online Views)

Gunnar Cario, Peter Rhein, Rita Mitlöhner, Martin Zimmermann, Obul R. Bandapalli, Renja Romey, Anja Moericke, Wolf-Dieter Ludwig, Richard Ratei, Martina U. Muckenthaler, Andreas E. Kulozik, Martin Schrappe, Martin Stanulla, Leonid Karawajew

https://doi.org/10.3324/haematol.2013.090225

Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (Alliance) (392 Online Views)

Meir Wetzler, Dorothy Watson, Wendy Stock, Gregory Koval, Flora A. Mulkey, Eva E. Hoke, John M. McCarty, William G. Blum, Bayard L. Powell, Guido Marcucci, Clara D. Bloomfield, Charles A. Linker, Richard A. Larson

https://doi.org/10.3324/haematol.2013.085811

STAT3-mediated activation of microRNA cluster 17~92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma (320 Online Views)

Elisa Spaccarotella, Elisa Pellegrino, Manuela Ferracin, Cristina Ferreri, Giuditta Cuccuru, Cuiling Liu, Javeed Iqbal, Daniela Cantarella, Riccardo Taulli, Paolo Provero, Ferdinando Di Cunto, Enzo Medico, Massimo Negrini, Wing C. Chan, Giorgio Inghirami, Roberto Piva

https://doi.org/10.3324/haematol.2013.088286

Monocyte count at diagnosis is a prognostic parameter in diffuse large B-cell lymphoma: results from a large multicenter study involving 1191 patients in the pre- and post-rituximab era (252 Online Views)

Tamar Tadmor, Alessia Bari, Stefano Sacchi, Luigi Marcheselli, Eliana Valentina Liardo, Irit Avivi, Noam Benyamini, Dina Attias, Samantha Pozzi, Maria Christina Cox, Luca Baldini, Maura Brugiatelli, Massimo Federico, Aaron Polliack

https://doi.org/10.3324/haematol.2013.088161

Aminobisphosphonates prevent the inhibitory effects exerted by lymph node stromal cells on anti-tumor Vδ 2 T lymphocytes in non-Hodgkin lymphomas (106 Online Views)

Alessandra Musso, Silvia Catellani, Paolo Canevali, Sara Tavella, Roberta Venè, Silvia Boero, Ivana Pierri, Marco Gobbi, Annalisa Kunkl, Jean-Louis Ravetti, Maria Raffaella Zocchi, Alessandro Poggi

https://doi.org/10.3324/haematol.2013.097311

Chronic lymphocytic leukemia in young (≤ 55 years) patients: a comprehensive analysis of prognostic factors and outcomes (1186 Online Views)

Sameer A. Parikh, Kari G. Rabe, Neil E. Kay, Timothy G. Call, Wei Ding, Susan M. Schwager, Deborah A. Bowen, Michael Conte, Diane F. Jelinek, Susan L. Slager, Tait D. Shanafelt

https://doi.org/10.3324/haematol.2013.086066

Bortezomib before and after autologous stem cell transplantation overcomes the negative prognostic impact of renal impairment in newly diagnosed multiple myeloma: a subgroup analysis from the HOVON-65/GMMG-HD4 trial (534 Online Views)

Christof Scheid, Pieter Sonneveld, Ingo G.H. Schmidt-Wolf, Bronno van der Holt, Laila el Jarari, Uta Bertsch, Hans Salwender, Sonja Zweegman, Igor Wolfgang Blau, Edo Vellenga, Katja Weisel, Michael Pfreundschuh, Kon-Siong Jie, Kai Neben, Helgi van de Velde, Ulrich Duehrsen, M. Ron Schaafsma, Walter Lindemann, Marie José Kersten, Norma Peter, Mathias Hänel, Sandra Croockewit, Hans Martin, Shulamiet Wittebol, Gerard MJ Bos, Marinus van Marwijk-Kooy, Pierre Wijermans, Hartmut Goldschmidt, Henk M. Lokhorst

https://doi.org/10.3324/haematol.2013.087585

Circulating clonotypic B cells in multiple myeloma and monoclonal gammopathy of undetermined significance (520 Online Views)

Leandro S. Thiago, Martin Perez-Andres, Ana Balanzategui, Maria E. Sarasquete, Bruno Paiva, Maria Jara-Acevedo, Paloma Barcena, Maria Luz Sanchez, Julia Almeida, Marcos González, Jesus F. San Miguel, Ramón Garcia-Sanz, Alberto Orfao

https://doi.org/10.3324/haematol.2013.092817

Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells (470 Online Views)

Jacqueline E. Noll, Sharon A. Williams, Christine M. Tong, Hongsheng Wang, Julie M. Quach, Louise E. Purton, Katherine Pilkington, Luen B. To, Andreas Evdokiou, Stan Gronthos, Andrew C.W. Zannettino

https://doi.org/10.3324/haematol.2013.090977

Glutathione transferase-A2 S112T polymorphism predicts survival, transplant-related mortality, busulfan and bilirubin blood levels after allogeneic stem cell transplantation (254 Online Views)

Francesca Bonifazi, Gianluca Storci, Giuseppe Bandini, Elena Marasco, Elisa Dan, Elena Zani, Fiorenzo Albani, Sara Bertoni, Andrea Bontadini, Sabrina De Carolis, Maria Rosaria Sapienza, Simonetta Rizzi, Maria Rosa Motta, Martina Ferioli, Paolo Garagnani, Michele Cavo, Vilma Mantovani, Massimiliano Bonafè

https://doi.org/10.3324/haematol.2013.089888

Treosulfan-based conditioning regimen for children and adolescents with hemophagocytic lymphohistiocytosis (327 Online Views)

Kai Lehmberg, Michael H. Albert, Rita Beier, Karin Beutel, Bernd Gruhn, Nicolaus Kröger, Roland Meisel, Ansgar Schulz, Daniel Stachel, Wilhelm Woessmann, Gritta Janka, Ingo Müller

https://doi.org/10.3324/haematol.2013.094730

Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis (265 Online Views)

Tatsuya Morishima, Ken-ichiro Watanabe, Akira Niwa, Hideyo Hirai, Satoshi Saida, Takayuki Tanaka, Itaru Kato, Katsutsugu Umeda, Hidefumi Hiramatsu, Megumu K. Saito, Kousaku Matsubara, Souichi Adachi, Masao Kobayashi, Tatsutoshi Nakahata, Toshio Heike

https://doi.org/10.3324/haematol.2013.083873

Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations (394 Online Views)

Tung-Liang Lin, Yasunobu Nagata, Hsiao-Wen Kao, Masashi Sanada, Yusuke Okuno, Chein-Fuang Huang, Der-Cherng Liang, Ming-Chung Kuo, Chang-Liang Lai, En-Hui Lee, Yu-Shu Shih, Hiroko Tanaka, Yuichi Shiraishi, Kenichi Chiba, Tung-Huei Lin, Jin-Hou Wu, Satoru Miyano, Seishi Ogawa, Lee-Yung Shih

https://doi.org/10.3324/haematol.2013.091249

Array comparative genomic hybridization and sequencing of 23 genes in 80 patients with myelofibrosis at chronic or acute phase (397 Online Views)

Mandy Brecqueville, Jérôme Rey, Raynier Devillier, Arnaud Guille, Rémi Gillet, José Adélaide, Véronique Gelsi-Boyer, Christine Arnoulet, Max Chaffanet, Marie-Joelle Mozziconacci, Norbert Vey, Daniel Birnbaum, Anne Murati

https://doi.org/10.3324/haematol.2013.091454

Prognostic impact of day 15 blast clearance in risk-adapted remission induction chemotherapy for younger patients with acute myeloid leukemia: long-term results of the multicenter prospective LAM-2001 trial by the GOELAMS study group (135 Online Views)

Sarah Bertoli, Pierre Bories, Marie C. Béné, Sylvie Daliphard, Bruno Lioure, Arnaud Pigneux, Norbert Vey, Jacques Delaunay, Vincent Leymarie, Isabelle Luquet, Odile Blanchet, Pascale Cornillet-Lefebvre, Mathilde Hunault, Didier Bouscary, Nathalie Fegueux, Philippe Guardiola, François Dreyfus, Jean Luc Harousseau, Jean Yves Cahn, Norbert Ifrah, Christian Récher

https://doi.org/10.3324/haematol.2013.091819

Farnesyltransferase inhibitor tipifarnib inhibits Rheb prenylation and stabilizes Bax in acute myelogenous leukemia cells (206 Online Views)

Husheng Ding, Jennifer S. McDonald, Seongseok Yun, Paula A. Schneider, Kevin L. Peterson, Karen S. Flatten, David A. Loegering, Ann L. Oberg, Shaun M. Riska, Shengbing Huang, Frank A. Sinicrope, Alex A. Adjei, Judith E. Karp, X. Wei Meng, Scott H. Kaufmann

https://doi.org/10.3324/haematol.2013.087734

In vivo activation of the human δ-globin gene: the therapeutic potential in β-thalassemic mice (198 Online Views)

Maria F. Manchinu, Maria F. Marongiu, Daniela Poddie, Carla Casu, Veronica Latini, Michela Simbula, Renzo Galanello, Paolo Moi, Antonio Cao, Susanna Porcu, Maria S. Ristaldi

https://doi.org/10.3324/haematol.2012.082768

NUP214-ABL1-mediated cell proliferation in T-cell acute lymphoblastic leukemia is dependent on the LCK kinase and various interacting proteins (706 Online Views)

Kim De Keersmaecker, Michaël Porcu, Luk Cox, Tiziana Girardi, Roel Vandepoel, Joyce Op de Beeck, Olga Gielen, Nicole Mentens, Keiryn L. Bennett, Oliver Hantschel

https://doi.org/10.3324/haematol.2013.088674

Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors (339 Online Views)

Linda Zuurbier, Alejandro Gutierrez, Charles G. Mullighan, Kirsten Canté-Barrett, A. Olivier Gevaert, Johan de Rooi, Yunlei Li, Willem K. Smits, Jessica G.C.A.M. Buijs-Gladdines, Edwin Sonneveld, A. Thomas Look, Martin Horstmann, Rob Pieters, Jules P.P. Meijerink

https://doi.org/10.3324/haematol.2013.090233

Letters to the Editor

Tricuspid regurgitant jet velocity and hospitalization in Tanzanian children with sickle cell anemia (100 Online Views)

Sharon E. Cox, Deogratias Soka, Fenella J. Kirkham, Charles R. J. Newton, Andrew M. Prentice, Julie Makani, Adel K. Younoszai

https://doi.org/10.3324/haematol.2013.089235

Molecular characterization and clinical impact of t(11;15)(q23;q14–15) MLL-CASC5 rearrangement (188 Online Views)

John Jeongseok Yang, Tae Sung Park, Seung-Tae Lee, Ja-Young Seo, Seung Hwan Oh, Eun Hae Cho, Sabine Strehl, Nora Mühlegger, Michael N. Dworzak, Jan Zuna, Dagmar Pospisilova, Claus Meyer, Rolf Marschalek, Hee-Jin Kim, Sun-Hee Kim

https://doi.org/10.3324/haematol.2013.095638

Prognostic significance of reproducible immunophenotypic markers of marrow dysplasia (82 Online Views)

Matteo G. Della Porta, Cristina Picone, Annamaria Tenore, Norio Yokose, Luca Malcovati, Mario Cazzola, Kiyoyuki Ogata

https://doi.org/10.3324/haematol.2013.097188