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October, 2008
No. 93 (10)

Editorials

New and old players in the hepcidin pathway (724 Online Views)

Clara Camaschella, Laura Silvestri

https://doi.org/10.3324/haematol.13724

Novel thrombopoietic agents: a new era for management of patients with thrombocytopenia (475 Online Views)

James N. George, Deirdra R. Terrell

https://doi.org/10.3324/haematol.13725

Allogeneic hematopoietic stem cell transplantation for myelofibrosis (259 Online Views)

Damiano Rondelli

https://doi.org/10.3324/haematol.13801

Adoptive T-cell therapy for malignant disorders (553 Online Views)

Daniel J. Powell, Bruce L. Levine

https://doi.org/10.3324/haematol.13717

Articles

Factors that influence short-term homing of human bone marrow-derived mesenchymal stem cells in a xenogeneic animal model (1197 Online Views)

Charalampia Kyriakou, Neil Rabin, Arnold Pizzey, Amit Nathwani, Kwee Yong

https://doi.org/10.3324/haematol.12553

Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response (995 Online Views)

Alessia Pagani, Laura Silvestri, Antonella Nai, Clara Camaschella

https://doi.org/10.3324/haematol.12508

A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron (2620 Online Views)

Maria Antonietta Melis, Milena Cau, Rita Congiu, Gabriella Sole, Susanna Barella, Antonio Cao, Mark Westerman, Mario Cazzola, Renzo Galanello

https://doi.org/10.3324/haematol.13342

Accumulation of hypoxia-inducible factor-1α protein and its role in the differentiation of myeloid leukemic cells induced by all-trans retinoic acid (876 Online Views)

Jing Zhang, Li-Ping Song, Ying Huang, Qian Zhao, Ke-Wen Zhao, Guo-Qiang Chen

https://doi.org/10.3324/haematol.13096

Changes in antithrombin and fibrinogen levels during induction chemotherapy with L-asparaginase in adult patients with acute lymphoblastic leukemia or lymphoblastic lymphoma. Use of supportive coagulation therapy and clinical outcome: the CAPELAL study (3325 Online Views)

Mathilde Hunault-Berger, Patrice Chevallier, Martine Delain, Claude-Eric Bulabois, Serge Bologna, Marc Bernard, Ingrid Lafon, Jérome Cornillon, Abdallah Maakaroun, Alexandra Tizon, Bruno Padrazzi, Norbert Ifrah, Yves Gruel

https://doi.org/10.3324/haematol.12948

The effect of a novel, small non-peptidyl molecule butyzamide on human thrombopoietin receptor and megakaryopoiesis (1670 Online Views)

Wataru Nogami, Hiroshi Yoshida, Kenzo Koizumi, Hajime Yamada, Kenji Abe, Akinori Arimura, Noriko Yamane, Koji Takahashi, Akiko Yamane, Atsushi Oda, Yoshikazu Tanaka, Hiroshi Takemoto, Yasuyuki Ohnishi, Yasuo Ikeda, Yoshitaka Miyakawa

https://doi.org/10.3324/haematol.12752

Molecular characterization of three novel splicing mutations causing factor V deficiency and analysis of the F5 gene splicing pattern (679 Online Views)

Claudia Dall'Osso, Ilaria Guella, Stefano Duga, Nadia Locatelli, Elvezia Maria Paraboschi, Marta Spreafico, Abdolreza Afrasiabi, Christoph Pechlaner, Flora Peyvandi, Maria Luisa Tenchini, Rosanna Asselta

https://doi.org/10.3324/haematol.12934

Allogeneic hematopoietic stem cell transplantation in myelofibrosis: the 20-year experience of the Gruppo Italiano Trapianto di Midollo Osseo (GITMO) (1010 Online Views)

Francesca Patriarca, Andrea Bacigalupo, Alessandra Sperotto, Miriam Isola, Franca Soldano, Barbara Bruno, Maria Teresa van Lint, Anna Paola Iori, Stella Santarone, Ferdinando Porretto, Pietro Pioltelli, Giuseppe Visani, Pasquale Iacopino, Renato Fanin, Alberto Bosi

https://doi.org/10.3324/haematol.12828

The effect of artificial antigen-presenting cells with preclustered anti-CD28/-CD3/-LFA-1 monoclonal antibodies on the induction of ex vivo expansion of functional human antitumor T cells (2971 Online Views)

Roberta Zappasodi, Massimo Di Nicola, Carmelo Carlo-Stella, Roberta Mortarini, Alessandra Molla, Claudia Vegetti, Salvatore Albani, Andrea Anichini, Alessandro M. Gianni

https://doi.org/10.3324/haematol.12521

Genetic engineering of virus-specific T cells with T-cell receptors recognizing minor histocompatibility antigens for clinical application (1100 Online Views)

Marieke Griffioen, H.M. Esther van Egmond, Helen Barnby-Porritt, Menno A.W.G. van der Hoorn, Renate S. Hagedoorn, Michel G.D. Kester, Nikolai Schwabe, Roel Willemze, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk

https://doi.org/10.3324/haematol.13067

Rapid identification of JAK2 exon 12 mutations using high resolution melting analysis (1171 Online Views)

Amy V. Jones, Nicholas C.P. Cross, Helen E. White, Anthony R. Green, Linda M. Scott

https://doi.org/10.3324/haematol.12883

Nucleophosmin mutation in Southeast Asian acute myeloid leukemia: eight novel variants, FLT3 coexistence and prognostic impact of NPM1/FLT3 mutations (1334 Online Views)

Chetsada Boonthimat, Wanna Thongnoppakhun, Chirayu U. Auewarakul

https://doi.org/10.3324/haematol.12937

Brief Reports

Serum hepcidin level and erythropoietic activity after hematopoietic stem cell transplantation (664 Online Views)

Junya Kanda, Chisaki Mizumoto, Hiroshi Kawabata, Hideyuki Tsuchida, Naohisa Tomosugi, Keitaro Matsuo, Takashi Uchiyama

https://doi.org/10.3324/haematol.12399

Long-term responses and outcomes following immunosuppressive therapy in large granular lymphocyte leukemia-associated pure red cell aplasia: a Nationwide Cohort Study in Japan for the PRCA Collaborative Study Group (1102 Online Views)

Naohito Fujishima, Ken-ichi Sawada, Makoto Hirokawa, Kazuo Oshimi, Koichi Sugimoto, Akira Matsuda, Masanao Teramura, Masamitsu Karasawa, Ayako Arai, Yuji Yonemura, Shinji Nakao, Akio Urabe, Mitsuhiro Omine, Keiya Ozawa

https://doi.org/10.3324/haematol.12871

Impaired dexamethasone-related increase of anticoagulants is associated with the development of osteonecrosis in childhood acute lymphoblastic leukemia (503 Online Views)

Mariel L. te Winkel, Inge M. Appel, Rob Pieters, Marry M. van den Heuvel-Eibrink

https://doi.org/10.3324/haematol.12956
Lymphoproliferative Disorders

CD49d expression is an independent risk factor of progressive disease in early stage chronic lymphocytic leukemia (1059 Online Views)

Davide Rossi, Antonella Zucchetto, Francesca Maria Rossi, Daniela Capello, Michaela Cerri, Clara Deambrogi, Stefania Cresta, Silvia Rasi, Lorenzo De Paoli, Chiara Lobetti Bodoni, Pietro Bulian, Giovanni Del Poeta, Marco Ladetto, Valter Gattei, Gianluca Gaidano

https://doi.org/10.3324/haematol.13103

Letters to the Editor

The transcription factor nuclear factor Y regulates the proliferation of myeloid progenitor cells (256 Online Views)

Sake van Wageningen, Gorica Nikoloski, Gerty Vierwinden, Ruth Knops, Bert A. van der Reijden, Joop H. Jansen

https://doi.org/10.3324/haematol.12425

Congenital sideroblastic anemia associated with germline polymorphisms reducing expression of FECH (1626 Online Views)

Jonathan S. Caudill, Hamayun Imran, Julie C. Porcher, David P. Steensma

https://doi.org/10.3324/haematol.12597
Thalassemia Syndromes

Correlation of liver iron concentration determined by R2 magnetic resonance imaging with serum ferritin in patients with thalassemia intermedia (1525 Online Views)

Ali Taher, Fuad El Rassi, Hussain Isma’eel, Suzane Koussa, Adlette Inati, Maria Domenica Cappellini

https://doi.org/10.3324/haematol.13098

Pregnancy outcome in patients with β-thalassemia intermedia at two tertiary care centers, in Beirut and Milan (1152 Online Views)

Anwar H. Nassar, Mohammed Naja, Claudia Cesaretti, Bruno Eprassi, Maria Domenica Cappellini, Ali Taher

https://doi.org/10.3324/haematol.13152
Thalassemia Syndromes

Continuous improvement of bone mineral density two years post zoledronic acid discontinuation in patients with thalassemia-induced osteoporosis: long-term follow-up of a randomized, placebo-controlled trial (350 Online Views)

Ersi Voskaridou, Dimitrios Christoulas, Marialena Konstantinidou, Evangelos Tsiftsakis, Panagiotis Alexakos, Evangelos Terpos

https://doi.org/10.3324/haematol.12849

Large deletion in UGT1A1 gene encompassing the promoter and the exon 1 responsible for Crigler-Najjar type I syndrome (471 Online Views)

François M. Petit, Marylise Hébert, Vincent Gajdos, Liliane Capel, Ridha M’Rad, Philippe Labrune

https://doi.org/10.3324/haematol.13295

Two novel variants of MOZ-CBP fusion transcripts in spontaneously remitted infant leukemia with t(1;16;8)(p13;p13;p11), a new variant of t(8;16)(p11;p13) (638 Online Views)

Kiminori Terui, Tomohiko Sato, Shinya Sasaki, Ko Kudo, Takuya Kamio, Etsuro Ito

https://doi.org/10.3324/haematol.13020

Pulmonary extramedullary hematopoiesis in patients with myelofibrosis undergoing allogeneic stem cell transplantation (1163 Online Views)

Sandeep Chunduri, Sujata Gaitonde, Stefan O. Ciurea, Ronald Hoffman, Damiano Rondelli

https://doi.org/10.3324/haematol.13203
Acute Myeloid Leukemia

Exon 8 splice site mutations in the gene encoding the E3-ligase CBL are associated with core binding factor acute myeloid leukemias (922 Online Views)

Saman Abbas, Gabriëlle Rotmans, Bob Löwenberg, Peter J.M. Valk

https://doi.org/10.3324/haematol.13187
Malignant Lymphomas

Genetic variation in genes expressed in the germinal center and risk of B cell lymphoma among Caucasians (297 Online Views)

Kathryn Scott, Peter J. Adamson, Eleanor V. Willett, Lisa J. Worrillow, James M. Allan

https://doi.org/10.3324/haematol.13159

Decision Making and Problem Solving

Recent trends in long-term survival of patients with chronic myelocytic leukemia: disclosing the impact of advances in therapy on the population level (722 Online Views)

Hermann Brenner, Adam Gondos, Dianne Pulte

https://doi.org/10.3324/haematol.13045

Online Only Articles

Factor XI mutation and the origin of Ashkenazi Jews (324 Online Views)

Avshalom Zoossmann-Diskin

https://doi.org/10.3324/haematol.13374

Reply to: [Factor XI mutation and the origin of Ashkenazi Jews. Haematologica 2008; 93:e59] (381 Online Views)

G. Zadra, R. Asselta, M.L. Tenchini, G. Castaman, U. Seligsohn, P.M. Mannucci, S. Duga

https://doi.org/10.3324/haematol.13480

Efficacy of cyclosporine as a single agent therapy in chronic idiopathic thrombocytopenic purpura (2042 Online Views)

D.R. Choudhary, R. Naithani, M. Mahapatra, R. Kumar, P. Mishra, R. Saxena

https://doi.org/10.3324/haematol.13481

Reply to: [Efficacy of cyclosporine as a single agent therapy in chronic idiopathic thrombocytopenic purpura”. Haematologica 2008; 93:e61] (355 Online Views)

G. Emilia, M. Luppi, M. Morselli, F. Forghieri, L. Potenza, G. Torelli

https://doi.org/10.3324/haematol.13631

Reply to: [Non-Hodgkin’s lymphoma and residential proximity to toxic industrial waste in Southern Israel. Haematologica 2005; 90:1709-10] (204 Online Views)

R.S. Carel

https://doi.org/10.3324/haematol.13357
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