CURRENT ISSUE
April, 2024
No. 109 (4)

Landmark papers in Hematology

Editorials

Review Articles

How we manage a high D-dimer (3008 Online Views)

Massimo Franchini, Daniele Focosi, Mario Piergiulio Pezzo, Pier Mannuccio Mannucci

https://doi.org/10.3324/haematol.2023.283966

Articles

Acute Leukemia

Use, variability, and justification of eligibility criteria for phase II and III clinical trials in acute leukemia (844 Online Views)

Andrew Hantel, Marlise R. Luskin, Irum Khan, Elizabeth Warner, Anand A. Patel, Thomas P. Walsh, Daniel J. DeAngelo, Christopher S. Lathan, Gregory A. Abel

https://doi.org/10.3324/haematol.2023.283723

Acute Lymphoblastic Leukemia

Susceptibility of pediatric acute lymphoblastic leukemia to STAT3 inhibition depends on p53 induction (1121 Online Views)

Luca Gasparoli, Clemence Virely, Alexia Tsakaneli, Noelia Che, Darren Edwards, Jack Bartram, Michael Hubank, Deepali Pal, Olaf Heidenreich, Joost H.A. Martens, Jasper de Boer, Owen Williams

https://doi.org/10.3324/haematol.2023.283613

Acute Myeloid Leukemia

Extended exposure to low doses of azacitidine induces differentiation of leukemic stem cells through activation of myeloperoxidase (1020 Online Views)

Danny V. Jeyaraju, Maryam Alapa, Ann Polonskaia, Alberto Risueño, Prakash Subramanyam, Amit Anand, Kaushik Ghosh, Charalampos Kyriakopoulos, Daiane Hemerich, Rose Hurren, Xiaoming Wang, Marcela Gronda, Aarif Ahsan, Hsiling Chiu, Geethu Thomas, Evan F. Lind, Daniel L Menezes, Aaron D. Schimmer, Patrick R. Hagner, Anita Gandhi, Anjan G. Thakurta

https://doi.org/10.3324/haematol.2023.283437

Prognostic value of European LeukemiaNet 2022 criteria and genomic clusters using machine learning in older adults with acute myeloid leukemia (1315 Online Views)

Silvia Park, Tong Yoon Kim, Byung-Sik Cho, Daehun Kwag, Jong-Mi Lee, MyungShin Kim, Yonggoo Kim, Jamin Koo, Anjali Raman, Tae Kon Kim, Hee-Je Kim

https://doi.org/10.3324/haematol.2023.283606

Immune checkpoint molecule DNAM-1/CD112 axis is a novel target for natural killer-cell therapy in acute myeloid leukemia (1261 Online Views)

Yuta Kaito, Emi Sugimoto, Fumi Nakamura, Yutaka Tsukune, Makoto Sasaki, Shunsuke Yui, Hiroki Yamaguchi, Susumu Goyama, Yasuhito Nannya, Kinuko Mitani, Hideto Tamura, Yoichi Imai

https://doi.org/10.3324/haematol.2023.282915

Cell Therapy & Immunotherapy

HLA-C*04:09N is expressed at the cell surface and triggers peptide-specific T-cell activation (716 Online Views)

Carlotta Welters, Marthe-Lina Welters, Serena Stadler, Lars Bullinger, Julian Strobel, Holger Hackstein, Arunraj Dhamodaran, Thomas Blankenstein, Leo Hansmann

https://doi.org/10.3324/haematol.2023.283812

Hemostasis

Histiocytic Disorder

Dabrafenib and trametinib in Langerhans cell histiocytosis and other histiocytic disorders (1691 Online Views)

Eily Cournoyer, Justin Ferrell, Susan Sharp, Anish Ray, Michael Jordan, Christopher Dandoy, Michael Grimley, Somak Roy, Robert Lorsbach, Arnold C. Merrow, Adam Nelson, Allison Bartlett, Jennifer Picarsic, Ashish Kumar

https://doi.org/10.3324/haematol.2023.283295

Non-Hodgkin Lymphoma

Immunochemotherapy plus lenalidomide for high-risk mantle cell lymphoma with measurable residual disease evaluation (1170 Online Views)

Zachary D. Epstein-Peterson, Esther Drill, Umut Aypar, Connie Lee Batlevi, Philip Caron, Ahmet Dogan, Pamela Drullinsky, John Gerecitano, Paul A. Hamlin, Caleb Ho, Allison Jacob, Ashlee Joseph, Leana Laraque, Matthew J. Matasar, Alison J. Moskowitz, Craig H. Moskowitz, Chelsea Mullins, Colette Owens, Gilles Salles, Heiko Schöder, David J. Straus, Anas Younes, Andrew D. Zelenetz, Anita Kumar

https://doi.org/10.3324/haematol.2023.282898

Outcome of combined modality treatment in first-line for stage I(E) peripheral T-cell lymphoma; a nationwide population-based cohort study from the Netherlands (1139 Online Views)

Frederik O. Meeuwes, Mirian Brink, Wouter Plattel, Marjolein W.M. van der Poel, Marie José Kersten, Mariëlle Wondergem, Lara Böhmer, F.J. Sherida H. Woei-A-Jin, Otto Visser, Rimke Oostvogels, Patty M. Jansen, Karen J. Neelis, Anne P.G. Crijns, Laurien A. Daniëls, Tjeerd J.F. Snijders, Joost S.P. Vermaat, Gerwin A. Huls, Marcel Nijland

https://doi.org/10.3324/haematol.2023.283174

MYC protein is a high-risk factor in mantle cell lymphoma and identifies cases beyond morphology, proliferation and TP53/p53 – a Nordic Lymphoma Group study (1041 Online Views)

Joana M. Rodrigues, Peter Hollander, Lina Schmidt, Eirinaios Gkika, Masoud Razmara, Darshan Kumar, Christian Geisler, Kirsten Grønbæk, Christian W. Eskelund, Riikka Räty, Arne Kolstad, Christer Sundström, Ingrid Glimelius, Anna Porwit, Mats Jerkeman, Sara Ek

https://doi.org/10.3324/haematol.2023.283352

Loncastuximab tesirine in relapsed/refractory diffuse large B-cell lymphoma: long-term efficacy and safety from the phase II LOTIS-2 study (2582 Online Views)

Paolo F. Caimi, Weiyun Z. Ai, Juan Pablo Alderuccio, Kirit M. Ardeshna, Mehdi Hamadani, Brian Hess, Brad S. Kahl, John Radford, Melhem Solh, Anastasios Stathis, Pier Luigi Zinzani, Ying Wang, Yajuan Qin, Luqiang Wang, Zhiying Cindy Xu, Carmelo Carlo-Stella

https://doi.org/10.3324/haematol.2023.283459

Polatuzumab vedotin plus bendamustine and rituximab or obinutuzumab in relapsed/refractory follicular lymphoma: a phase Ib/II study (1617 Online Views)

Christopher R. Flowers, Matthew J. Matasar, Alex F. Herrera, Mark Hertzberg, Sarit Assouline, Judit Demeter, Andrew McMillan, Amitkumar Mehta, Stephen Opat, Marek Trnňný, Lisa Musick, Jamie Hirata, Annie Yang, Laurie H. Sehn

https://doi.org/10.3324/haematol.2023.283557

Plasma Cell Disorders

Ribosomal protein S3 mediates drug resistance of proteasome inhibitor: potential therapeutic application in multiple myeloma (1101 Online Views)

Gege Chen, Xuejie Gao, Xinyan Jia, Yingcong Wang, Li Xu, Dandan Yu, Shuaikang Chang, Hui Deng, Ke Hu, Guanli Wang, Bo Li, Zhijian Xu, Yumeng Lu, Huaping Wang, Ting Zhang, Dongliang Song, Guang Yang, Xiaosong Wu, Huabin Zhu, Weiliang Zhu, Jumei Shi

https://doi.org/10.3324/haematol.2023.282789

Stem Cell Transplantation

Targeting TFH cells is a novel approach for donor-specific antibody desensitization of allograft candidates: an in vitro and in vivo study (737 Online Views)

Ning Ma, Wei-Bing Wu, Xiang-Yu Zhao, Lan-Ping Xu, Xiao-Hui Zhang, Yu Wang, Xiao-Dong Mo, Yuan-Yuan Zhang, Xiao-Su Zhao, Yu-Qian Sun, Yi-Fei Cheng, Kai-Yan Liu, Ying-Jun Chang, Xiao-Jun Huang

https://doi.org/10.3324/haematol.2023.283698

Letters to the Editor

Genome-wide assessment of genetic risk loci for childhood acute lymphoblastic leukemia in Japanese patients (1003 Online Views)

Mayumi Hangai, Takahisa Kawaguchi, Masatoshi Takagi, Keitaro Matsuo, Soyoung Jeon, Charleston W.K. Chiang, Andrew T. Dewan, Adam J. de Smith, Toshihiko Imamura, Yasuhiro Okamoto, Akiko M. Saito, Takao Deguchi, Michiaki Kubo, Yoichi Tanaka, Yoko Ayukawa, Toshinari Hori, Kentaro Ohki, Nobutaka Kiyokawa, Takeshi Inukai, Yuki Arakawa, Makiko Mori, Daisuke Hasegawa, Daisuke Tomizawa, Hiroko Fukushima, Yuki Yuza, Yasushi Noguchi, Yuichi Taneyama, Setsuo Ota, Hiroaki Goto, Masakatsu Yanagimachi, Dai Keino, Kazutoshi Koike, Daisuke Toyama, Yozo Nakazawa, Kozue Nakamura, Koichi Moriwaki, Yujin Sekinaka, Daisuke Morita, Shinsuke Hirabayashi, Yosuke Hosoya, Yuri Yoshimoto, Hiroki Yoshihara, Miwa Ozawa, Shinobu Kobayashi, Naho Morisaki, Tshewang Gyeltshen, Osamu Takahashi, Yukinori Okada, Makiko Matsuda, Toshihiro Tanaka, Johji Inazawa, Junko Takita, Yasushi Ishida, Akira Ohara, Catherine Metayer, Joseph L. Wiemels, Xiaomei Ma, Shuki Mizutani, Katsuyoshi Koh, Yukihide Momozawa, Keizo Horibe, Fumihiko Matsuda, Motohiro Kato, Atsushi Manabe, Kevin Y. Urayama

https://doi.org/10.3324/haematol.2023.282914

BH3 profiling as pharmacodynamic biomarker for the activity of BH3 mimetics (1093 Online Views)

Rongqing Aaron Pan, Youzhen Wang, Shumei Qiu, Mariana Villalobos-Ortiz, Jeremy Ryan, Erick Morris, Ensar Halilovic, Anthony Letai

https://doi.org/10.3324/haematol.2023.283060

Subcutaneous injection of IHP-102 prevents lung vaso-occlusion in sickle cell disease mice (706 Online Views)

Rikesh K. Dubey, Ravi Vats, Tomasz Brzoska, Tomasz W. Kaminski, Omika Katoch, Jesus Tejero, Gabriel Njikang, John Paderi, Prithu Sundd

https://doi.org/10.3324/haematol.2023.283716

Long-term outcome after autologous BCR::ABL1-negative peripheral blood stem cell transplantation in adults with Philadelphia-positive acute lymphoblastic leukemia: a comparative study (498 Online Views)

Leo Caillot, Mathieu Leclerc, Emmanuel Jacques Raphael Sleiman, Ivan Sloma, Orianne Wagner-Ballon, Alexis Claudel, Florence Beckerich, Rabah Redjoul, Christine Robin, Vincent Parinet, Cecile Pautas, Dehbia Menouche, Selwa Bouledroua, Ludovic Cabanne, Yakout Nait-Sidenas, Eric Gautier, Helene Rouard, Ingrid Lafon, Yves Chalandon, Nicolas Boissel, Denis Caillot, Sebastien Maury

https://doi.org/10.3324/haematol.2023.283742

Low-dose azacitidine, pioglitazone and all-trans retinoic acid is safe in patients aged ≥60 years with acute myeloid leukemia refractory to standard induction chemotherapy (AMLSG 26-16/AML-ViVA): results of the safety run-in phase (979 Online Views)

Daniel Heudobler, Florian Luke, Joachim Hahn, Matthias Grube, Pavla Schlosser, Stephan Kremers, Thomas Sudhoff, Jorg Westermann, Marie Luise Hutter-Kronke, Richard F. Schlenk, Daniela Weber, Peter Paschka, Florian Zeman, Hartmut Dohner, Wolfgang Herr, Albrecht Reichle, Simone Thomas

https://doi.org/10.3324/haematol.2023.283864

Catheter-related thrombosis in stem cell recipients: comparison of different types of catheter (588 Online Views)

Slawomir Milczarek, Piotr Kulig, Oliwia Piotrowska, Alina Zuchmanska, Anna Bielikowicz, Bogusław Machalinski

https://doi.org/10.3324/haematol.2023.283924

Small myeloid subclones are present at diagnosis of multiple myeloma in patients who develop secondary myelodysplastic syndromes (569 Online Views)

Guillaume Escure, Elise Fournier, Cynthia Saade, Lama Hasan Bou Issa, Inès Arib, Rémi Tilmont, Nicolas Gazeau, Binta M. Thiam, Morgane Chovet, Maxime Delforge, Nicolas Gower, Léa Fléchon, Doriane Cavalieri, Paul Chauvet, Morgane Nudel, Laure Goursaud, Céline Berthon, Bruno Quesnel, Thierry Facon, Claude Preudhomme, Nicolas Duployez, Salomon Manier

https://doi.org/10.3324/haematol.2023.284050

CD38 expression by plasma cells in extramedullary multiple myeloma (732 Online Views)

Laura Notarfranchi, Fabrizio Accardi, Cristina Mancini, Eugenia Martella, Sabrina Bonomini, Roberta Segreto, Rosanna Vescovini, Anna Benedetta Dalla Palma, Gabriella Sammarelli, Giannalisa Todaro, Paola Storti, Jessica Burroughs-Garcia, Nicolas Thomas Iannozzi, Vincenzo Raimondi, Oxana Lungu, Stefania Ricci, Luisa Craviotto, Nicola Giuliani

https://doi.org/10.3324/haematol.2023.284169

Case Reports

A patient with minimal myeloma treatment who survived for 20 years (1330 Online Views)

Alenka Djarmila Behsen, Esten Nymoen Vandsemb, Tobias Schmidt Slørdahl, Henrik Hjorth-Hansen, Petter Quist-Paulsen, Kristine Misund, Anne-Marit Sponaas, Anders Waage

https://doi.org/10.3324/haematol.2023.283563

Erratum

Erratum to: Retrospective analysis of pacritinib in patients with myelofibrosis and severe thrombocytopenia (246 Online Views)

Srdan Verstovsek, Ruben Mesa, Moshe Talpaz, Jean-Jacques Kiladjian, Claire N. Harrison, Stephen T. Oh, Alessandro M. Vannucchi, Raajit Rampal, Bart L. Scott, Sarah A. Buckley, Adam R. Craig, Karisse Roman-Torres, John O. Mascarenhas

https://doi.org/10.3324/haematol.2023.284815

Erratum to: Utility of clinical comprehensive genomic characterization for diagnostic categorization in patients presenting with hypocellular bone marrow failure syndromes (158 Online Views)

Piers Blombery, Lucy Fox, Georgina L. Ryland, Ella R. Thompson, Jennifer Lickiss, Michelle McBean, Satwica Yerneni, Alison Trainer, David Hughes, Anthea Greenway, Francoise Mechinaud, Erica M. Wood, Graham J. Lieschke, Jeff Szer, Pasquale Barbaro, John Roy, Joel Wight, Elly Lynch, Melissa Martyn, Clara Gaff, David Ritchie

https://doi.org/10.3324/haematol.2023.284760