March, 2023
No. 108 (3)

Landmark papers in Hematology

Editorials

Review Articles

Articles

Acute Myeloid Leukemia

Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning (4345 Online Views)

Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina M. Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang E. Berdel, Wolfgang Hiddemann, Frank Kroschinsky, Johannes Schetelig, Uwe Platzbecker, Carsten Müller-Tidow, Tim Sauer, Hubert Serve, Claudia Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan Krause, Mathias Hänel, Christoph Schliemann, Maher Hanoun, Christian Thiede, Martin Bornhäuser, Karsten Wendt, Jan Moritz Middeke

https://doi.org/10.3324/haematol.2021.280027

A phase Ib trial of mivavotinib (TAK-659), a dual SYK/FLT3 inhibitor, in patients with relapsed/refractory acute myeloid leukemia (1612 Online Views)

Keith W. Pratz, Jason Kaplan, Moshe Levy, Dale Bixby, Patrick W. Burke, Harry Erba, Trisha M. Wise-Draper, Gail J. Roboz, Nikolaos Papadantonakis, Trivikram Rajkhowa, Daniela Hernandez, Iwona Dobler, Richard C. Gregory, Cheryl Li, Shining Wang, Kate Stumpo, Karuppiah Kannan, Harry Miao, Mark Levis

https://doi.org/10.3324/haematol.2022.281216

Acute Lymphoblastic Leukemia

Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement (3464 Online Views)

Simon Bomken, Amir Enshaei, Edward C. Schwalbe, Aneta Mikulasova, Yunfeng Dai, Masood Zaka, Kent T.M. Fung, Matthew Bashton, Huezin Lim, Lisa Jones, Nefeli Karataraki, Emily Winterman, Cody Ashby, Andishe Attarbaschi, Yves Bertrand, Jutta Bradtke, Barbara Buldini, G.A. Amos Burke, Giovanni Cazzaniga, Gudrun Gohring, Hesta A. de Groot-Kruseman, Claudia Haferlach, Luca Lo Nigro, Mayur Parihar, Adriana Plesa, Emma Seaford, Edwin Sonneveld, Sabine Strehl, Vincent H.J. van der Velden, Vikki Rand, Stephen P. Hunger, Christine J. Harrison, Chris M. Bacon, Frederik W. van Delft, Mignon L. Loh, John Moppett, Josef Vormoor, Brian A. Walker, Anthony V. Moorman, Lisa J. Russell

https://doi.org/10.3324/haematol.2021.280557

STAT5 does not drive steroid resistance in T-cell acute lymphoblastic leukemia despite the activation of BCL2 and BCLXL following glucocorticoid treatment (1980 Online Views)

Jordy C.G. van der Zwet, Valentina Cordo’, Jessica G.C.A.M. Buijs-Gladdines, Rico Hagelaar, Willem K. Smits, Eric Vroegindeweij, Laura T.M. Graus, Vera Poort, Marloes Nulle, Rob Pieters, Jules P.P. Meijerink

https://doi.org/10.3324/haematol.2021.280405

Three-year results from phase I of ZUMA-4: KTE-X19 in pediatric relapsed/refractory acute lymphoblastic leukemia (3674 Online Views)

Alan S. Wayne, Van Huynh, Nobuko Hijiya, Rayne H. Rouce, Patrick A. Brown, Joerg Krueger, Carrie L. Kitko, Edward Dela Ziga, Michelle L. Hermiston, Michael K. Richards, Andre Baruchel, Petra C. Schuberth, John Rossi, Lang Zhou, Lovely Goyal, Rajul Jain, Remus Vezan, Behzad Kharabi Masouleh, Daniel W. Lee

https://doi.org/10.3324/haematol.2022.280678

Bone Marrow Transplantation

CD56brightCD16 natural killer cells as an important regulatory mechanism in chronic graft-versus-host disease (2323 Online Views)

Madeline Lauener, Shima AzadPour, Sayeh Abdossamadi, Vaishnavi Parthasarathy, Bernard Ng, Elena Ostroumov, Geoffrey D.E. Cuvelier, Megan K. Levings, Katherine N. MacDonald, Amina Kariminia, Kirk R. Schultz

https://doi.org/10.3324/haematol.2022.280653

Coagulation & its Disorders

APOLD1 loss causes endothelial dysfunction involving cell junctions, cytoskeletal architecture, and Weibel-Palade bodies, while disrupting hemostasis (3088 Online Views)

Simon Stritt, Paquita Nurden, Alan T. Nurden, Jean-François Schved, Jean-Claude Bordet, Maguelonne Roux, Marie-Christine Alessi, David-Alexandre Trégouët, Taija Mäkinen, Muriel Giansily-Blaizot

https://doi.org/10.3324/haematol.2022.280816

Non-Hodgkin Lymphoma

Impact of positron emission tomography - computed tomography status on progression-free survival for relapsed follicular lymphoma patients undergoing autologous stem cell transplantation (2106 Online Views)

Toby A. Eyre, Sally F. Barrington, Jessica Okosun, Clementina Abamba, Rachel M. Pearce, Julia Lee, Ben Carpenter, Charles R. Crawley, Adrian J.C. Bloor, Maria Gilleece, Emma Nicholson, Nimish Shah, Kim Orchard, Ram Malladi, William M. Townsend

https://doi.org/10.3324/haematol.2021.280287

Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation (1811 Online Views)

Yvonne J. Thus, Martin F.M. de Rooij, Nathalie Swier, Roderick L. Beijersbergen, Jeroen E.J. Guikema, Marie-José Kersten, Eric Eldering, Steven T. Pals, Arnon P. Kater, Marcel Spaargaren

https://doi.org/10.3324/haematol.2022.281668

Oral HDAC inhibitor tucidinostat in patients with relapsed or refractory peripheral T-cell lymphoma: phase IIb results (4626 Online Views)

Shinya Rai, Won Seog Kim, Kiyoshi Ando, Ilseung Choi, Koji Izutsu, Norifumi Tsukamoto, Masahiro Yokoyama, Kunihiro Tsukasaki, Junya Kuroda, Jun Ando, Michihiro Hidaka, Youngil Koh, Hirohiko Shibayama, Toshiki Uchida, Deok Hwan Yang, Kenji Ishitsuka, Kenichi Ishizawa, Jin Seok Kim, Hong Ghi Lee, Hironobu Minami, Hyeon Seok Eom, Mitsutoshi Kurosawa, Jae Hoon Lee, Jong Seok Lee, Won Sik Lee, Hirokazu Nagai, Takero Shindo, Dok Hyun Yoon, Shinichiro Yoshida, Mireille Gillings, Hiroshi Onogi, Kensei Tobinai

https://doi.org/10.3324/haematol.2022.280996

Treatment patterns and outcomes in relapsed/refractory follicular lymphoma: results from the international SCHOLAR-5 study (2567 Online Views)

Paola Ghione, M Lia Palomba, Hervé Ghesquieres, Sabela Bobillo, Anik R Patel, Myrna Nahas, Steve Kanters, Kevin Deighton, Anthony Hatswell, Long Ma, Eve H. Limbrick-Oldfield, Julia Thornton Snider, Sally W. Wade, Maria Teresa Riberio, John Radford, Sara Beygi, John Gribben

https://doi.org/10.3324/haematol.2022.281421

Plasma Cell Disorders

Lenalidomide-based triplet regimens in first relapsed multiple myeloma patients: real-world evidence from a propensity score matched analysis (2177 Online Views)

Silvia Mangiacavalli, Claudio Salvatore Cartia, Monica Galli, Sara Pezzatti, Angelo Belotti, Francesca Fazio, Roberto Mina, Magda Marcatti, Anna Cafro, Renato Zambello, Laura Paris, Gregorio Barilà, Cecilia Olivares, Alessandra Pompa, Rita Mazza, Francesca Farina, Martina Soldarini, Pietro Benvenuti, Giuseppina Pagani, Michele Palumbo, Valeria Masoni, Virginia Valeria Ferretti, Catherine Klersy, Luca Arcaini, Maria Teresa Petrucci

https://doi.org/10.3324/haematol.2022.281342

Platelet Biology & its Disorders

Enhancing regulatory T-cell function via inhibition of high mobility group box 1 protein signaling in immune thrombocytopenia (2338 Online Views)

Haoyi Wang, Tianshu Yu, Ning An, Yunqi Sun, Pengcheng Xu, Panpan Han, Yajing Zhao, Lingjun Wang, Xiaofei Ni, Yubin Li, Guosheng Li, Yanfeng Liu, Jun Peng, Ming Hou, Yu Hou

https://doi.org/10.3324/haematol.2022.281557

Red Cell Biology & its Disorders

Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease (2567 Online Views)

Iryna A. Khasabova, Jacob Gable, Malcolm Johns, Sergey G. Khasabov, Alexander E. Kalyuzhny, Mikhail Y. Golovko, Svetlana A. Golovko, Stacy Kiven, Kalpna Gupta, Virginia S. Seybold, Donald A. Simone

https://doi.org/10.3324/haematol.2021.280460

Variation and impact of polygenic hematologic traits in monogenic sickle cell disease (1578 Online Views)

Thomas Pincez, Ken Sin Lo, Anne-Laure Pham Hung d’Alexandry d’Orengiani, Melanie E. Garrett, Carlo Brugnara, Allison E. Ashley-Koch, Marilyn J. Telen, Frederic Galacteros, Philippe Joly, Pablo Bartolucci, Guillaume Lettre

https://doi.org/10.3324/haematol.2022.281180

Letters to the Editor

International multicenter retrospective analysis of thiotepa-based autologous stem cell transplantation for secondary central nervous system lymphoma (2219 Online Views)

Jahanzaib Khwaja, Amy A. Kirkwood, Lisa K. Isbell, Sara Steffanoni, Harshita Goradia, Lisa Pospiech, Thomas Fail, Emma Nicholson, Kate Fletcher, Kim M. Linton, Katrina E. Parsons, Nagah Elmusharaf, Lydia Eccersley, Toby A. Eyre, Sridhar Chaganti, Jeffrey Smith, Nisha Thakrar, Alexandra Kutilina, Teresa Calimeri, Nicolas Martinez-Calle, Dima El-Sharkawi, Wendy Osborne, Gerald Illerhaus, Christopher P. Fox, Andrés J.M. Ferreri, Elisabeth Schorb, Kate Cwynarski

https://doi.org/10.3324/haematol.2022.281640

Delayed hemolytic transfusion reaction in children with sickle cell disease: first 5-year retrospective study in mainland France (1234 Online Views)

Claire Falguière, Slimane Allali, Bassem Khazem, Annie Kamdem, Cécile Arnaud, Marie Belloy, Corinne Guitton, Marie-Hélène Odièvre, Sophie Pertuisel, Cecile Dumesnil, Cécile Guillaumat, Nathalie Garrec, Alexandra Gauthier, Perrine Mahe, Valerie Soussan-Banini, Laure Le-Carrer, Etienne Merlin, Audrey David, Beatrice Pellegrino, Catherine Paillard, Jean-Francois Brasme, Marie Lagarde, France Pirenne, Corinne Pondarre

https://doi.org/10.3324/haematol.2022.281050

Unique pathologic features and gene expression signatures distinguish blastoid high-grade B-cell lymphoma from B-acute lymphoblastic leukemia/lymphoma (1607 Online Views)

Lianqun Qiu, Jie Xu, Pei Lin, Evan N. Cohen, Guilin Tang, Sa A. Wang, Mahsa Khanlari, Wei Wang, Joseph D. Khoury, Sergej Konoplev, C. Cameron Yin, Jeffrey L. Jorgensen, Francisco Vega, L. Jeffrey Medeiros, Shaoying Li

https://doi.org/10.3324/haematol.2022.281646

Prognostic impact of pretreatment immunoglobulin clonal composition in pediatric B-lymphoblastic leukemia (884 Online Views)

Carol Fries, Lik Wee Lee, Meenakshi Devidas, Yunfeng Dai, Karen R. Rabin, Sumit Gupta, Mignon L. Loh, Ilan R Kirsch, Brent Wood, Rachel E. Rau

https://doi.org/10.3324/haematol.2022.281146

Identification of multiple genetic loci associated with red blood cell alloimmunization in mice (4773 Online Views)

Arijita Jash, Heather L. Howie, Ariel M. Hay, Chance John Luckey, Krystalyn E. Hudson, Peter C. Thomson, Sarah J. Ratcliffe, Mark Smolkin, James C. Zimring

https://doi.org/10.3324/haematol.2022.281767

Dysfunctional subsets of CD39+ T cells, distinct from PD-1+, driven by leukemic extracellular vesicles in myeloid leukemias (4521 Online Views)

Julian Swatler, Domenico Lo Tartaro, Rebecca Borella, Marta Brewinska-Olchowik, Annamaria Paolini, Anita Neroni, Laura Turos-Korgul, Milena Wiech, Ewa Kozlowska, Dominik Cysewski, Wioleta Grabowska-Pyrzewicz, Urszula Wojda, Grzegorz Basak, Rafael J. Argüello, Andrea Cossarizza, Sara De Biasi, Katarzyna Piwocka

https://doi.org/10.3324/haematol.2022.281713

COVID-19 pandemic affects the ability of negative D-dimer to identify venous thromboembolism patients at low risk of recurrence: insights from the Apidulcis study (2243 Online Views)

Gualtiero Palareti, Cristina Legnani, Daniela Poli, Walter Ageno, Vittorio Pengo, Sophie Testa, Alberto Tosetto, Paolo Prandoni; NEUROFARBA, University of Florence, Italy (Collaborative Group)

https://doi.org/10.3324/haematol.2022.282130

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