December, 2022
No. 107 (12)

Hematological Historical Vignette

About the Cover

Landmark papers in Hematology

Editorials

Review Series

Measurable Residual Disease

Articles

Acute Myeloid Leukemia

Clinical relevance of an objective flow cytometry approach based on limit of detection and limit of quantification for measurable residual disease assessment in acute myeloid leukemia. A post-hoc analysis of the GIMEMA AML1310 trial (2079 Online Views)

Francesco Buccisano, Raffaele Palmieri, Alfonso Piciocchi, Valentina Arena, Luca Maurillo, Maria-Ilaria Del Principe, Giovangiacinto Paterno, Maria-Antonietta Irno-Consalvo, Tiziana Ottone, Mariadomenica Divona, Consuelo Conti, Daniela Fraboni, Serena Lavorgna, William Arcese, Maria Teresa Voso, Adriano Venditti

https://doi.org/10.3324/haematol.2021.279777

Bone Marrow Failure

Impaired immunosuppressive role of myeloid-derived suppressor cells in acquired aplastic anemia (2418 Online Views)

Peiyuan Dong, Lingyun Chen, Hongfei Wu, Jiali Huo, Zhongxing Jiang, Yingqi Shao, Xiang Ren, Jinbo Huang, Xingxin Li, Min Wang, Neng Nie, Jing Zhang, Peng Jin, Yizhou Zheng, Meili Ge

https://doi.org/10.3324/haematol.2021.280292

Hemostasis

Thymosin β4 is essential for thrombus formation by controlling the G-actin/F-actin equilibrium in platelets (4202 Online Views)

Inga Scheller, Sarah Beck, Vanessa Göb, Carina Gross, Raluca A. I. Neagoe, Katja Aurbach, Markus Bender, David Stegner, Zoltan Nagy, Bernhard Nieswandt

https://doi.org/10.3324/haematol.2021.278537

Chronic Myeloid Leukemia

Kinetics of early and late molecular recurrences after first-line imatinib cessation in chronic myeloid leukemia: updated results from the STIM2 trial (1975 Online Views)

Stéphanie Dulucq, Franck E. Nicolini, Delphine Rea, Pascale Cony-Makhoul, Aude Charbonnier, Martine Escoffre-Barbe, Valérie Coiteux, Pascal Lenain, Françoise Rigal-Huguet, Jixing Liu, Agnès Guerci-Bresler, Laurence Legros, Jean-Christophe Ianotto, Martine Gardembas, Pascal Turlure, Viviane Dubruille, Philippe Rousselot, Juliana Martiniuc, Henry Jardel, Hyacinthe Johnson-Ansah, Bertrand Joly, Tawfiq Henni, Emilie Cayssials, Patricia Zunic, Marc G. Berger, Bruno Villemagne, Fanny Robbesyn, Stephane Morisset, François-Xavier Mahon, Gabriel Etienne

https://doi.org/10.3324/haematol.2022.280811

Complications in Hematology

Clinical features of hepatitis E infections in patients with hematologic disorders (1602 Online Views)

Susanne Ghandili, Cecilia Lindhauer, Sven Pischke, Julian Schulze zur Wiesch, Philipp H. von Kroge, Susanne Polywka, Carsten Bokemeyer, Walter Fiedler, Nicolaus Kröger, Francis Ayuk, Raissa Adjallé, Franziska Modemann

https://doi.org/10.3324/haematol.2022.280853

Hematopoiesis

Schlafen2 is a regulator of quiescence in adult murine hematopoietic stem cells (1927 Online Views)

Sarah Warsi, Maria Dahl, Emma M. K. Smith, Anna Rydstrom, Els Mansell, Valgardur Sigurdsson, Julia Sjoberg, Shamit Soneji, Emma Rorby, Kavitha Siva, Tan H. M. Grahn, Yang Liu, Ulrika Blank, Goran Karlsson, Stefan Karlsson

https://doi.org/10.3324/haematol.2021.279799

Hodgkin Lymphoma

High-risk stage IIB Hodgkin lymphoma treated in the H10 and AHL2011 trials: total metabolic tumor volume is a useful risk factor to stratify patients at baseline (2466 Online Views)

Cédric Rossi, Marc André, Jehan Dupuis, Franck Morschhauser, Bertrand Joly, Julien Lazarovici, Hervé Ghesquières, Aspasia Stamatoullas, Emmanuelle Nicolas-Virelizier, Pierre Feugier, Anne-Claire Gac, Hannah Moatti, Luc-Matthieu Fornecker, Bénédicte Deau, Clémentine Joubert, Catherine Fortpied, John Raemaekers, Massimo Federico, Salim Kanoun, Michel Meignan, Alexandra Traverse-Glehen, Anne-Ségolène Cottereau, René-Olivier Casasnova

https://doi.org/10.3324/haematol.2021.280004

Non-Hodgkin Lymphoma

The IL32/BAFF axis supports prosurvival dialogs in the lymphoma ecosystem and is disrupted by NIK inhibition (2435 Online Views)

Salomé Decombis, Antonin Papin, Céline Bellanger, Clara Sortais, Christelle Dousset, Yannick Le Bris, Thiphanie Riveron, Stéphanie Blandin, Philippe Hulin, Benoit Tessoulin, Mathieu Rouel, Steven Le Gouill, Agnès Moreau-Aubry, Catherine Pellat-Deceunynck, David Chiron

https://doi.org/10.3324/haematol.2021.279800

Quality of Life

Comparable long-term outcomes between upfront haploidentical and identical sibling donor transplant in aplastic anemia: a national registry-based study (3601 Online Views)

Zheng-Li Xu, Lan-Ping Xu, De-Pei Wu, Shun-Qing Wang, Xi Zhang, Rui Xi, Su-Jun Gao, Ling-Hui Xia, Jian-Min Yang, Ming Jiang, Xin Wang, Qi-Fa Liu, Jia Chen, Ming Zhou, Xiao-Jun Huang

https://doi.org/10.3324/haematol.2022.280758

T-cell Leukemia/lymphoma

Regulation of human T-cell leukemia virus type 1 antisense promoter by myocyte enhancer factor-2C in the context of adult T-cell leukemia and lymphoma (1805 Online Views)

Kiran K. Madugula, Julie Joseph, Catherine DeMarino, Rashida Ginwala, Vanessa Teixeira, Zafar K. Khan, Dominic Sales, Sydney Wilson, Fatah Kashanchi, Amanda W. Rushing, Isabelle Lemasson, Edward W. Harhaj, Murali Janakiram, B. Hilda Ye, Pooja Jain

https://doi.org/10.3324/haematol.2021.279542

Letters to the Editor

Onset of blast crisis in chronic myeloid leukemia patients in treatment-free remission (2181 Online Views)

Stephanie Dulucq, Sandrine Hayette, Jean-Michel Cayuela, Frédéric Bauduer, Kaddour Chabane, Patrice Chevallier, Pascale Cony-Makhoul, Pascale Flandrin-Gresta, Caroline Le Jeune, Yannick Le Bris, Laurence Legros, Hervé Maisonneuve, Lydia Roy, Francois-Xavier Mahon, Ivan Sloma, Delphine Rea, Franck Emmanuel Nicolini

https://doi.org/10.3324/haematol.2022.280740

Circulating endothelial cells and the study of vascular injury in children undergoing hematopoietic stem cell transplant (1471 Online Views)

Anthony Sabulski, Sheyar Abdullah, Nathan Luebbering, Benjamin Aunins, Caitlin Castillo, Kelly Lake, Alexandra Duell, Lauren Strecker, Lucille Giordullo, William Broomhead, Scott Dimeo, Elizabeth A. Odegard, Jason T. Blackard, Assem Ziady, Alix E. Seif, Christopher E. Dandoy, Benjamin L. Laskin, Sonata Jodele, Stella M. Davies

https://doi.org/10.3324/haematol.2022.280788

Investigational venetoclax combination therapy in acute myeloid leukemia – a systematic review and meta-analysis (1734 Online Views)

Shai Shimony, Alon Rozental, Jan P. Bewersdorf, Aaron D. Goldberg, Eytan M. Stein, Alyssa A. Grimshaw, Richard M. Stone, Daniel J. DeAngelo, Ofir Wolach, Maximilian Stahl

https://doi.org/10.3324/haematol.2022.281453

Under-representation of ethnic minorities in early phase clinical trials for multiple myeloma (2379 Online Views)

Samir Asher, Aikaterini Kazantzi, Fatjon Dekaj, Luke Steventon, Aisha Khatun, Louise Ainley, Annabel McMillan, Neil Rabin, Ashu Wechalekar, Jonathan Sive, Charalampia Kyriakou, Xenofon Papanikolaou, Ke Xu, Shameem Mahmood, Brendan Wisniowski, Lydia Lee, Kwee Yong, Rakesh Popat

https://doi.org/10.3324/haematol.2022.281322

αβT- and B-cell-depleted HLA-haploidentical hematopoietic stem cell transplantation in children with myelodysplastic syndromes (1390 Online Views)

Pietro Merli, Daria Pagliara, Tommaso Mina, Valentina Bertaina, Giuseppina Li Pira, Stefania Lazzaro, Simone Biagini, Federica Galaverna, Luisa Strocchio, Roberto Carta, Maria Luigia Catanoso, Francesco Quagliarella, Marco Becilli, Emilia Boccieri, Francesca Del Bufalo, Arianna Panigari, Annalisa Agostini, Lucia Pedace, Simone Pizzi, Cesare Perotti, Mattia Algeri, Marco Zecca, Franco Locatelli

https://doi.org/10.3324/haematol.2022.280698

Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization (1623 Online Views)

Fiona E. Reed, Nicole M. Eskow, Elizabeth Min, Maximillian Carlino, Rubia Mancuso, Nayoung Kwon, Elenoe C. Smith, Shannon T. Larsuel, Lin Wang, Vanessa Scanlon, Diane S. Krause

https://doi.org/10.3324/haematol.2021.280499

Case Reports

Mass spectrometry-based proteomics in clinical practice amyloid typing: state-of-the-art from a French nationwide cohort (1743 Online Views)

Magali Colombat, Margot Gaspard, Mylène Camus, Jessica Dalloux-Chioccioli, Audrey Delas, Elsa Poullot, Anissa Moktefi, Arnaud François, Anne Moreau, Jean-Bapiste Gibier, Pierre Raynaud, Antoine Huart, Alexis Piedrafita, Julia Gilhodes, Olivier Lairez, Gilles Grateau, Sophie Georgin-Lavialle, Hervé Maisonneuve, Philippe Moreau, Arnaud Jaccard, Franck Bridoux, Violaine Plante-Bordeneuve, Thibaud Damy, Hervé Mal, Pierre Brousset, Sophie Valleix, Odile Burlet-Schiltz

https://doi.org/10.3324/haematol.2022.281431

Errata Corrige