Vol. 104 No. 2 (2019): February, 2019

Xiaomin Wang, Yanan Gao, Juan Gao, Minghao Li, Mi Zhou, Jinhong Wang, Yakun Pang, Hui Cheng, Chase Yuan, Yajing Chu, Yu Jiang, Jianfeng Zhou, Hongbo R. Luo, Zhenyu Ju, Tao Cheng, Weiping Yuan

https://doi.org/10.3324/haematol.2018.194811

Aplastic anemia in the elderly: a nationwide survey on behalf of the French Reference Center for Aplastic Anemia (4042 Online Views)

Adrien Contejean, Matthieu Resche-Rigon, Jérôme Tamburini, Marion Alcantara, Fabrice Jardin, Etienne Lengliné, Lionel Adès, Didier Bouscary, Ambroise Marçais, Delphine Lebon, Cécile Chabrot, Louis Terriou, Fiorenza Barraco, Anne Banos, Lucile Bussot, Jean-Yves Cahn, Pierre Hirsch, Natacha Maillard, Laurence Simon, Luc-Matthieu Fornecker, Gerard Socié, Regis Peffault de Latour, Flore Sicre de Fontbrune

https://doi.org/10.3324/haematol.2018.198440

Exposure to non-inherited maternal antigens by breastfeeding affects antibody responsiveness (2827 Online Views)

Henk Schonewille, Jon J. van Rood, Esther P. Verduin, Leo M.G. van de Watering, Geert W. Haasnoot, Frans H.J. Claas, Dick Oepkes, Enrico Lopriore, Anneke Brand

https://doi.org/10.3324/haematol.2018.199406

Treatment outcomes and prognostic factors in adult patients with secondary hemophagocytic lymphohistiocytosis not associated with malignancy (14302 Online Views)

Jae-Ho Yoon, Sung-Soo Park, Young-Woo Jeon, Sung-Eun Lee, Byung-Sik Cho, Ki-Seong Eom, Yoo-Jin Kim, Hee-Je Kim, Seok Lee, Chang-Ki Min, Seok-Goo Cho, Jong Wook Lee

https://doi.org/10.3324/haematol.2018.198655

Comprehensive genetic diagnosis of acute myeloid leukemia by next-generation sequencing (3417 Online Views)

Elisabeth K.M. Mack, André Marquardt, Danny Langer, Petra Ross, Alfred Ultsch, Michael G. Kiehl, Hildegard I.D. Mack, Torsten Haferlach, Andreas Neubauer, Cornelia Brendel

https://doi.org/10.3324/haematol.2018.194258

A novel deep targeted sequencing method for minimal residual disease monitoring in acute myeloid leukemia (1803 Online Views)

Esther Onecha, Maria Linares, Inmaculada Rapado, Yanira Ruiz-Heredia, Pilar Martinez-Sanchez, Teresa Cedena, Marta Pratcorona, Jaime Perez Oteyza, Pilar Herrera, Eva Barragan, Pau Montesinos, Jose Antonio Garcia Vela, Elena Magro, Eduardo Anguita, Angela Figuera, Rosalia Riaza, Pilar Martinez-Barranco, Beatriz Sanchez-Vega, Josep Nomdedeu, Miguel Gallardo, Joaquin Martinez-Lopez, Rosa Ayala

https://doi.org/10.3324/haematol.2018.194712

Targeted RNA-sequencing for the quantification of measurable residual disease in acute myeloid leukemia (2015 Online Views)

Laura W. Dillon, Sheida Hayati, Gregory W. Roloff, Ilker Tunc, Mehdi Pirooznia, Antonina Mitrofanova, Christopher S. Hourigan

https://doi.org/10.3324/haematol.2018.203133

Persistent IDH1/2 mutations in remission can predict relapse in patients with acute myeloid leukemia (2904 Online Views)

Chi Young Ok, Sanam Loghavi, Dawen Sui, Peng Wei, Rashmi Kanagal-Shamanna, C. Cameron Yin, Zhuang Zuo, Mark J. Routbort, Guilin Tang, Zhenya Tang, Jeffrey L. Jorgensen, Rajyalakshmi Luthra, Farhad Ravandi, Hagop M. Kantarjian, Courtney D. DiNardo, L. Jeffrey Medeiros, Sa A. Wang, Keyur P. Patel

https://doi.org/10.3324/haematol.2018.191148

Prognostic implications of additional genomic lesions in adult Philadelphia chromosome-positive acute lymphoblastic leukemia (1971 Online Views)

Anna Lucia Fedullo, Monica Messina, Loredana Elia, Alfonso Piciocchi, Valentina Gianfelici, Alessia Lauretti, Stefano Soddu, Maria Cristina Puzzolo, Clara Minotti, Felicetto Ferrara, Bruno Martino, Patrizia Chiusolo, Valeria Calafiore, Stefania Paolini, Marco Vignetti, Antonella Vitale, Anna Guarini, Robin Foà, Sabina Chiaretti

https://doi.org/10.3324/haematol.2018.196055

Hypersensitivity reactions to asparaginase in mice are mediated by anti-asparaginase IgE and IgG and the immunoglobulin receptors FcεRI and FcγRIII (1627 Online Views)

Sanjay Rathod, Manda Ramsey, Mary V. Relling, Fred D. Finkelman, Christian A. Fernandez

https://doi.org/10.3324/haematol.2018.199448

JUNB, DUSP2, SGK1, SOCS1 and CREBBP are frequently mutated in T-cell/histiocyte-rich large B-cell lymphoma (2514 Online Views)

Bianca Schuhmacher, Julia Bein, Tobias Rausch, Vladimir Benes, Thomas Tousseyn, Martine Vornanen, Maurilio Ponzoni, Lorenz Thurner, Randy Gascoyne, Christian Steidl, Ralf Küppers, Martin-Leo Hansmann, Sylvia Hartmann

https://doi.org/10.3324/haematol.2018.203224

T-cell inflamed tumor microenvironment predicts favorable prognosis in primary testicular lymphoma (1677 Online Views)

Suvi-Katri Leivonen, Marjukka Pollari, Oscar Brück, Teijo Pellinen, Matias Autio, Marja-Liisa Karjalainen-Lindsberg, Susanna Mannisto, Pirkko-Liisa Kellokumpu-Lehtinen, Olli Kallioniemi, Satu Mustjoki, Sirpa Leppä

https://doi.org/10.3324/haematol.2018.200105

miR-497 suppresses cycle progression through an axis involving CDK6 in ALK-positive cells (1049 Online Views)

Coralie Hoareau-Aveilla, Cathy Quelen, Annabelle Congras, Nina Caillet, Delphine Labourdette, Christine Dozier, Pierre Brousset, Laurence Lamant, Fabienne Meggetto

https://doi.org/10.3324/haematol.2018.195131

Tailored approaches grounded on immunogenetic features for refined prognostication in chronic lymphocytic leukemia (1694 Online Views)

Panagiotis Baliakas, Theodoros Moysiadis, Anastasia Hadzidimitriou, Aliki Xochelli, Sabine Jeromin, Andreas Agathangelidis, Mattias Mattsson, Lesley-Ann Sutton, Eva Minga, Lydia Scarfò, Davide Rossi, Zadie Davis, Neus Villamor, Helen Parker, Jana Kotaskova, Evangelia Stalika, Karla Plevova, Larry Mansouri, Diego Cortese, Alba Navarro, Julio Delgado, Marta Larrayoz, Emma Young, Achilles Anagnostopoulos, Karin E. Smedby, Gunnar Juliusson, Oonagh Sheehy, Mark Catherwood, Jonathan C. Strefford, Niki Stavroyianni, Chrysoula Belessi, Sarka Pospisilova, David Oscier, Gianluca Gaidano, Elias Campo, Claudia Haferlach, Paolo Ghia, Richard Rosenquist, Kostas Stamatopoulos

https://doi.org/10.3324/haematol.2018.195032

Allogeneic transplantation of multiple myeloma patients may allow long-term survival in carefully selected patients with acceptable toxicity and preserved quality of life (5054 Online Views)

Christine Greil, Monika Engelhardt, Gabriele Ihorst, Katja Schoeller, Hartmut Bertz, Reinhard Marks, Robert Zeiser, Justus Duyster, Hermann Einsele, Jürgen Finke, Ralph Wäsch

https://doi.org/10.3324/haematol.2018.200881

Long-term follow up of tandem autologous-allogeneic hematopoietic cell transplantation for multiple myeloma (1854 Online Views)

Enrico Maffini, Barry E. Storer, Brenda M. Sandmaier, Benedetto Bruno, Firoozeh Sahebi, Judith A. Shizuru, Thomas R. Chauncey, Parameswaran Hari, Thoralf Lange, Michael A. Pulsipher, Peter A. McSweeney, Leona Holmberg, Pamela S. Becker, Damian J. Green, Marco Mielcarek, David G. Maloney, Rainer Storb

https://doi.org/10.3324/haematol.2018.200253

The TLR7 ligand R848 prevents mouse graft-versus-host disease and cooperates with anti-interleukin-27 antibody for maximal protection and regulatory T-cell upregulation (1035 Online Views)

Mélanie Gaignage, Reece G. Marillier, Perrine M. Cochez, Laure Dumoutier, Catherine Uyttenhove, Jean-Paul Coutelier, Jacques Van Snick

https://doi.org/10.3324/haematol.2018.195628

Anti-HLA antibodies with complementary and synergistic interaction geometries promote classical complement activation on platelets (1887 Online Views)

Maaike Rijkers, David Schmidt, Nina Lu, Cynthia S.M. Kramer, Sebastiaan Heidt, Arend Mulder, Leendert Porcelijn, Frans H.J. Claas, Frank W.G. Leebeek, A.J. Gerard Jansen, Ilse Jongerius, Sacha S. Zeerleder, Gestur Vidarsson, Jan Voorberg, Masja de Haas

https://doi.org/10.3324/haematol.2018.201665

Endothelial protein C receptor (EPCR) expression marks human fetal liver hematopoietic stem cells (1301 Online Views)

Agatheeswaran Subramaniam, Mehrnaz Safaee Talkhoncheh, Mattias Magnusson, Jonas Larsson

https://doi.org/10.3324/haematol.2018.198515

Prevalence and management of iron overload in pyruvate kinase deficiency: report from the Pyruvate Kinase Deficiency Natural History Study (1241 Online Views)

Eduard J. van Beers, Stephanie van Straaten, D. Holmes Morton, Wilma Barcellini, Stefan W. Eber, Bertil Glader, Hassan M. Yaish, Satheesh Chonat, Janet L. Kwiatkowski, Jennifer A. Rothman, Mukta Sharma, Ellis J. Neufeld, Sujit Sheth, Jenny M. Despotovic, Nina Kollmar, Dagmar Pospíšilová, Christine M. Knoll, Kevin Kuo, Yves D. Pastore, Alexis A. Thompson, Peter E. Newburger, Yaddanapudi Ravindranath, Winfred C. Wang, Marcin W. Wlodarski, Heng Wang, Susanne Holzhauer, Vicky R. Breakey, Madeleine Verhovsek, Joachim Kunz, Melissa A. McNaull, Melissa J. Rose, Heather A. Bradeen, Kathryn Addonizio, Anran Li, Hasan Al-Sayegh, Wendy B. London, Rachael F. Grace

https://doi.org/10.3324/haematol.2018.196295

Bone marrow mesenchymal stem/stromal cells from risk-stratified acute myeloid leukemia patients are anti-inflammatory in in vivo preclinical models of hematopoietic reconstitution and severe colitis (817 Online Views)

Rafael Diaz de la Guardia, Belen Lopez-Millan, Heleia Roca-Ho, Clara Bueno, Francisco Gutiérrez-Agüera, Jose Luis Fuster, Eduardo Anguita, Samanta Romina Zanetti, Susana Vives, Josep Nomdedeu, Robert Sackstein, Jessie Lavoie, Elena Gónzalez-Rey, Mario Delgado, Michael Rosu-Myles, Pablo Menendez

https://doi.org/10.3324/haematol.2018.196568

Relationship between CD33 expression, splicing polymorphism, and in vitro cytotoxicity of gemtuzumab ozogamicin and the CD33/CD3 BiTE® AMG 330 (846 Online Views)

George S. Laszlo, Mary E. Beddoe, Colin D. Godwin, Olivia M. Bates, Chelsea J. Gudgeon, Kimberly H. Harrington, Roland B. Walter

https://doi.org/10.3324/haematol.2018.202069

Continuous high dosing of lenalidomide in relapsed, refractory or older newly diagnosed acute myeloid leukemia patients not suitable for other treatment options - results from a phase I study (927 Online Views)

Marie Luise Hütter-Krönke, Walter Fiedler, Andrea Kündgen, Jürgen Krauter, Marie von Lilienfeld-Toal, Hartmut Döhner, Richard F. Schlenk

https://doi.org/10.3324/haematol.2018.199794

ABVD plus rituximab versus ABVD alone for advanced stage, high-risk classical Hodgkin lymphoma: a randomized phase 2 study (3036 Online Views)

Paolo Strati, Michelle A. Fanale, Yasuhiro Oki, Francesco Turturro, Luis E Fayad, Nancy L. Bartlett, Douglas E. Gladstone, Yvette L. Kasamon, Carol S. Portlock, Wyndham H. Wilson, Andre Goy, Anas Younes, Hun Ju Lee

https://doi.org/10.3324/haematol.2018.199844

Efficacy of venetoclax monotherapy in patients with relapsed, refractory mantle cell lymphoma after Bruton tyrosine kinase inhibitor therapy (2323 Online Views)

Toby A. Eyre, Harriet S. Walter, Sunil Iyengar, George Follows, Matthew Cross, Christopher P. Fox, Andrew Hodson, Josh Coats, Santosh Narat, Nick Morley, Martin J.S. Dyer, Graham P. Collins

https://doi.org/10.3324/haematol.2018.198812

Long non-coding RNA NEAT1 shows high expression unrelated to molecular features and clinical outcome in multiple myeloma (1047 Online Views)

Elisa Taiana, Domenica Ronchetti, Vanessa Favasuli, Katia Todoerti, Martina Manzoni, Nicola Amodio, Pierfrancesco Tassone, Luca Agnelli, Antonino Neri

https://doi.org/10.3324/haematol.2018.201301

Unrelated cord blood transplantation and post-transplant cyclophosphamide (890 Online Views)

Andrea Bacigalupo, Simona Sica, Luca Laurenti, Federica Sora’, Sabrina Giammarco, Elisabetta Metafuni, Idanna Innocenti, Francesco Autore, Luciana Teofili, Maria Bianchi, Patrizia Chiusolo

https://doi.org/10.3324/haematol.2018.202598