October, 2017
No. 102 (10)

Editorials

Review Articles

Articles

Iron Metabolism & its Disorders

Blood Transfusion

Amotosalen/ultraviolet A pathogen inactivation technology reduces platelet activatability, induces apoptosis and accelerates clearance (374 Online Views)

Simona Stivala, Sara Gobbato, Laura Infanti, Martin F. Reiner, Nicole Bonetti, Sara C. Meyer, Giovanni G. Camici, Thomas F. Lüscher, Andreas Buser, Jürg H. Beer

https://doi.org/10.3324/haematol.2017.164137

Platelet Biology & its Disorders

Bone marrow pathologic abnormalities in familial platelet disorder with propensity for myeloid malignancy and germline RUNX1 mutation (525 Online Views)

Rashmi Kanagal-Shamanna, Sanam Loghavi, Courtney D. DiNardo, L. Jeffrey Medeiros, Guillermo Garcia-Manero, Elias Jabbour, Mark J. Routbort, Rajyalakshmi Luthra, Carlos E. Bueso-Ramos, Joseph D. Khoury

https://doi.org/10.3324/haematol.2017.167726

Bone Marrow Failure

Incidence and outcome of acquired aplastic anemia: real-world data from patients diagnosed in Sweden from 2000–2011 (1519 Online Views)

Krista Vaht, Magnus Göransson, Kristina Carlson, Cecilia Isaksson, Stig Lenhoff, Anna Sandstedt, Bertil Uggla, Jacek Winiarski, Per Ljungman, Mats Brune, Per-Ola Andersson

https://doi.org/10.3324/haematol.2017.169862

Rapamycin is highly effective in murine models of immune-mediated bone marrow failure (448 Online Views)

Xingmin Feng, Zenghua Lin, Wanling Sun, Maile K. Hollinger, Marie J. Desierto, Keyvan Keyvanfar, Daniela Malide, Pawel Muranski, Jichun Chen, Neal S. Young

https://doi.org/10.3324/haematol.2017.163675

Chronic Myeloid Leukemia

Prognostic discrimination based on the EUTOS long-term survival score within the International Registry for Chronic Myeloid Leukemia in children and adolescents (263 Online Views)

Frédéric Millot, Joëlle Guilhot, Meinolf Suttorp, Adalet Meral Güneş, Petr Sedlacek, Eveline De Bont, Chi Kong Li, Krzysztof Kalwak, Birgitte Lausen, Srdjana Culic, Michael Dworzak, Emilia Kaiserova, Barbara De Moerloose, Farah Roula, Andrea Biondi, André Baruchel

https://doi.org/10.3324/haematol.2017.170035

Acute Myeloid Leukemia

Vosaroxin in combination with decitabine in newly diagnosed older patients with acute myeloid leukemia or high-risk myelodysplastic syndrome (167 Online Views)

Naval Daver, Hagop Kantarjian, Guillermo Garcia-Manero, Elias Jabbour, Gautam Borthakur, Mark Brandt, Sherry Pierce, Kenneth Vaughan, Jing Ning, Graciela M. Nogueras González, Keyur Patel, Jeffery Jorgensen, Naveen Pemmaraju, Tapan Kadia, Marina Konopleva, Michael Andreeff, Courtney DiNardo, Jorge Cortes, Renee Ward, Adam Craig, Farhad Ravandi

https://doi.org/10.3324/haematol.2017.168732

Long non-coding RNA expression profile in cytogenetically normal acute myeloid leukemia identifies a distinct signature and a new biomarker in NPM1-mutated patients (222 Online Views)

Etienne De Clara, Morgane Gourvest, Hanjing Ma, François Vergez, Marie Tosolini, Sébastien Dejean, Cécile Demur, Eric Delabesse, Christian Recher, Christian Touriol, Maria Paola Martelli, Brunangelo Falini, Pierre Brousset, Marina Bousquet

https://doi.org/10.3324/haematol.2017.171645

Acute Lymphoblastic Leukemia

Prolonged versus standard native E. coli asparaginase therapy in childhood acute lymphoblastic leukemia and non-Hodgkin lymphoma: final results of the EORTC-CLG randomized phase III trial 58951 (184 Online Views)

Veerle Mondelaers, Stefan Suciu, Barbara De Moerloose, Alina Ferster, Françoise Mazingue, Geneviève Plat, Karima Yakouben, Anne Uyttebroeck, Patrick Lutz, Vitor Costa, Nicolas Sirvent, Emmanuel Plouvier, Martine Munzer, Maryline Poirée, Odile Minckes, Frédéric Millot, Dominique Plantaz, Philip Maes, Claire Hoyoux, Hélène Cavé, Pierre Rohrlich, Yves Bertrand, Yves Benoit

https://doi.org/10.3324/haematol.2017.165845

Loss-of-function but not dominant-negative intragenic IKZF1 deletions are associated with an adverse prognosis in adult BCR-ABL-negative acute lymphoblastic leukemia (307 Online Views)

Benjamin Kobitzsch, Nicola Gökbuget, Stefan Schwartz, Richard Reinhardt, Monika Brüggemann, Andreas Viardot, Ralph Wäsch, Michael Starck, Eckhard Thiel, Dieter Hoelzer, Thomas Burmeister

https://doi.org/10.3324/haematol.2016.161273

Hodgkin Lymphoma

Secondary malignant neoplasms, progression-free survival and overall survival in patients treated for Hodgkin lymphoma: a systematic review and meta-analysis of randomized clinical trials (310 Online Views)

Dennis A. Eichenauer, Ingrid Becker, Ina Monsef, Nicholas Chadwick, Vitaliana de Sanctis, Massimo Federico, Catherine Fortpied, Alessandro M. Gianni, Michel Henry-Amar, Peter Hoskin, Peter Johnson, Stefano Luminari, Monica Bellei, Alessandro Pulsoni, Matthew R. Sydes, Pinuccia Valagussa, Simonetta Viviani, Andreas Engert, Jeremy Franklin

https://doi.org/10.3324/haematol.2017.167478

Non-Hodgkin Lymphoma

Exome sequencing identifies recurrent BCOR alterations and the absence of KLF2, TNFAIP3 and MYD88 mutations in splenic diffuse red pulp small B-cell lymphoma (307 Online Views)

Laurent Jallades, Lucile Baseggio, Pierre Sujobert, Sarah Huet, Kaddour Chabane, Evelyne Callet-Bauchu, Aurélie Verney, Sandrine Hayette, Jean-Pierre Desvignes, David Salgado, Nicolas Levy, Christophe Béroud, Pascale Felman, Françoise Berger, Jean-Pierre Magaud, Laurent Genestier, Gilles Salles, Alexandra Traverse-Glehen

https://doi.org/10.3324/haematol.2016.160192

Plasma Cell Disorders

Impact of prior therapy on the efficacy and safety of oral ixazomib-lenalidomide-dexamethasone vs. placebo-lenalidomide-dexamethasone in patients with relapsed/refractory multiple myeloma in TOURMALINE-MM1 (444 Online Views)

María-Victoria Mateos, Tamas Masszi, Norbert Grzasko, Markus Hansson, Irwindeep Sandhu, Ludek Pour, Luísa Viterbo, Sharon R. Jackson, Anne-Marie Stoppa, Peter Gimsing, Mehdi Hamadani, Gabriela Borsaru, Deborah Berg, Jianchang Lin, Alessandra Di Bacco, Helgi van de Velde, Paul G. Richardson, Philippe Moreau

https://doi.org/10.3324/haematol.2017.170118

The BET bromodomain inhibitor CPI203 improves lenalidomide and dexamethasone activity in in vitro and in vivo models of multiple myeloma by blockade of Ikaros and MYC signaling (251 Online Views)

Tania Díaz, Vanina Rodríguez, Ester Lozano, Mari-Pau Mena, Marcos Calderón, Laura Rosiñol, Antonio Martínez, Natalia Tovar, Patricia Pérez-Galán, Joan Bladé, Gaël Roué, Carlos Fernández de Larrea

https://doi.org/10.3324/haematol.2017.164632

Cell Therapy & Immunotherapy

Notch2 blockade enhances hematopoietic stem cell mobilization and homing (159 Online Views)

Weihuan Wang, Shuiliang Yu, Jay Myers, Yiwei Wang, William W. Xin, Marwah Albakri, Alison W. Xin, Ming Li, Alex Y. Huang, Wei Xin, Christian W. Siebel, Hillard M. Lazarus, Lan Zhou

https://doi.org/10.3324/haematol.2017.168674

Complications in Hematology

Characterization of atrial fibrillation adverse events reported in ibrutinib randomized controlled registration trials (697 Online Views)

Jennifer R. Brown, Javid Moslehi, Susan O’Brien, Paolo Ghia, Peter Hillmen, Florence Cymbalista, Tait D. Shanafelt, Graeme Fraser, Simon Rule, Thomas J. Kipps, Steven Coutre, Marie-Sarah Dilhuydy, Paula Cramer, Alessandra Tedeschi, Ulrich Jaeger, Martin Dreyling, John C. Byrd, Angela Howes, Michael Todd, Jessica Vermeulen, Danelle F. James, Fong Clow, Lori Styles, Rudy Valentino, Mark Wildgust, Michelle Mahler, Jan A. Burger

https://doi.org/10.3324/haematol.2017.171041

Online Only Articles

Feasibility study of online yoga for symptom management in patients with myeloproliferative neoplasms (190 Online Views)

Jennifer Huberty, Ryan Eckert, Krisstina Gowin, Jules Mitchell, Amylou C. Dueck, Brenda F. Ginos, Linda Larkey, Ruben Mesa

https://doi.org/10.3324/haematol.2017.168583

Calreticulin as a novel B-cell receptor antigen in chronic lymphocytic leukemia (118 Online Views)

Elisa ten Hacken, Maria Gounari, Jaap Willem Back, Ekaterina Shimanovskaya, Lydia Scarfò, Ekaterina Kim, Jared Burks, Maurilio Ponzoni, Giuseppe Alvise Ramirez, William G. Wierda, Zeev Estrov, Michael J. Keating, Alessandra Ferrajoli, Kostas Stamatopoulos, Paolo Ghia, Jan A. Burger

https://doi.org/10.3324/haematol.2017.169102

Ibrutinib may impair serological responses to influenza vaccination (202 Online Views)

Abby P. Douglas, Jason A. Trubiano, Ian Barr, Vivian Leung, Monica A. Slavin, Constantine S. Tam

https://doi.org/10.3324/haematol.2017.164285

Reliable subtype classification of diffuse large B-cell lymphoma samples from GELA LNH2003 trials using the Lymph2Cx gene expression assay (157 Online Views)

Jean-Philippe Jais, Thierry Jo Molina, Philippe Ruminy, David Gentien, Cecile Reyes, David W. Scott, Lisa M. Rimsza, George Wright, Randy D. Gascoyne, Louis M. Staudt, Corinne Haioun, Herve Tilly, Philippe Gaulard, Gilles A. Salles, Fabrice Jardin, Karen Leroy

https://doi.org/10.3324/haematol.2017.166827

Changes in the incidence of candidemia and related mortality in patients with hematologic malignancies in the last ten years. A SEIFEM 2015-B report (109 Online Views)

Livio Pagano, Giulia Dragonetti, Chiara Cattaneo, Francesco Marchesi, Barbara Veggia, Alessandro Busca, Anna Candoni, Lucia Prezioso, Marianna Criscuolo, Simone Cesaro, Mario Delia, Rosa Fanci, Marta Stanzani, Antonella Ferrari, Bruno Martino, Lorella Melillo, Gianpaolo Nadali, Edoardo Simonetti, Stelvio Ballanti, Marco Picardi, Carlo Castagnola, Nunzia Decembrino, Marco Gazzola, Nicola Stefano Fracchiolla, Valentina Mancini, Annamaria Nosari, Maria Ilaria Del Principe, Franco Aversa, Mario Tumbarello

https://doi.org/10.3324/haematol.2017.172536

Genome-wide association study of clinical parameters in immunoglobulin light chain amyloidosis in three patient cohorts (180 Online Views)

Iman Meziane, Stefanie Huhn, Miguel Inacio da Silva Filho, Niels Weinhold, Chiara Campo, Jolanta Nickel, Per Hoffmann, Markus M. Nöthen, Karl-Heinz Jöckel, Stefano Landi, Jonathan S. Mitchell, David Johnson, Anna Jauch, Gareth J. Morgan, Richard Houlston, Hartmut Goldschmidt, Paolo Milani, Giampaolo Merlini, Dorota Rowcieno, Philip Hawkins, Ute Hegenbart, Giovanni Palladini, Ashutosh Wechalekar, Asta Försti, Stefan O. Schönland, Kari Hemminki

https://doi.org/10.3324/haematol.2017.171108

Red blood cell Gardos channel (KCNN4): the essential determinant of erythrocyte dehydration in hereditary xerocytosis (236 Online Views)

Raphaël Rapetti-Mauss, Véronique Picard, Corinne Guitton, Khaldoun Ghazal, Valérie Proulle, Catherine Badens, Olivier Soriani, Loïc Garçon, Hélène Guizouarn

https://doi.org/10.3324/haematol.2017.171389

Failure of long-term lamivudine prophylaxis in patients with resolved hepatitis B infection undergoing chemotherapy and allogenic hematopoietic stem cell transplantation for hematological malignancies: two case reports (73 Online Views)

Glenda Grossi, Mauro Viganò, Floriana Facchetti, Sara Labanca, Alessandro Loglio, Anna Dodero, Vittorio Montefusco, Paolo Corradini, Anna Cafro, Roberto Cairoli, Massimo Colombo, Pietro Lampertico

https://doi.org/10.3324/haematol.2017.168609