November, 2016
No. 101 (11)

Editorials

Review Articles

New insights on hereditary erythrocyte membrane defects

Immacolata Andolfo, Roberta Russo, Antonella Gambale, Achille Iolascon

https://doi.org/10.3324/haematol.2016.142463

Osteonecrosis in children with acute lymphoblastic leukemia

Marina Kunstreich, Sebastian Kummer, Hans-Juergen Laws, Arndt Borkhardt, Michaela Kuhlen

https://doi.org/10.3324/haematol.2016.147595

Articles

Red Cell Biology & Its Disorders

Gene panel sequencing improves the diagnostic work-up of patients with idiopathic erythrocytosis and identifies new mutations

Carme Camps, Nayia Petousi, Celeste Bento, Holger Cario, Richard R. Copley, Mary Frances McMullin, Richard van Wijk, Peter J. Ratcliffe, Peter A. Robbins, Jenny C. Taylor

https://doi.org/10.3324/haematol.2016.144063

Blood Transfusion

Human neutrophil peptides and complement factor Bb in pathogenesis of acquired thrombotic thrombocytopenic purpura

Wenjing Cao, Huy P. Pham, Lance A. Williams, Jenny McDaniel, Rance C. Siniard, Robin G. Lorenz, Marisa B. Marques, X. Long Zheng

https://doi.org/10.3324/haematol.2016.149021

Platelet Biology & its Disorders

Comparison of two dosing schedules for subcutaneous injections of low-dose anti-CD20 veltuzumab in relapsed immune thrombocytopenia

Howard A. Liebman, Mansoor N. Saleh, James B. Bussel, O. George Negrea, Heather Horne, William A. Wegener, David M. Goldenberg

https://doi.org/10.3324/haematol.2016.146738

Clinical and pathogenic features of ETV6-related thrombocytopenia with predisposition to acute lymphoblastic leukemia

Federica Melazzini, Flavia Palombo, Alessandra Balduini, Daniela De Rocco, Caterina Marconi, Patrizia Noris, Chiara Gnan, Tommaso Pippucci, Valeria Bozzi, Michela Faleschini, Serena Barozzi, Michael Doubek, Christian A. Di Buduo, Katerina Stano Kozubik, Lenka Radova, Giuseppe Loffredo, Sarka Pospisilova, Caterina Alfano, Marco Seri, Carlo L. Balduini, Alessandro Pecci, Anna Savoia

https://doi.org/10.3324/haematol.2016.147496

Bone Marrow Failure

Genetic features of myelodysplastic syndrome and aplastic anemia in pediatric and young adult patients

Siobán B. Keel, Angela Scott, Marilyn Sanchez-Bonilla, Phoenix A. Ho, Suleyman Gulsuner, Colin C. Pritchard, Janis L. Abkowitz, Mary-Claire King, Tom Walsh, Akiko Shimamura

https://doi.org/10.3324/haematol.2016.149476

Acute Myeloid Leukemia

An operational definition of primary refractory acute myeloid leukemia allowing early identification of patients who may benefit from allogeneic stem cell transplantation

Paul Ferguson, Robert K. Hills, Angela Grech, Sophie Betteridge, Lars Kjeldsen, Michael Dennis, Paresh Vyas, Anthony H. Goldstone, Donald Milligan, Richard E. Clark, Nigel H. Russell, Charles Craddock

https://doi.org/10.3324/haematol.2016.148825

Effect of age and body weight on toxicity and survival in pediatric acute myeloid leukemia: results from NOPHO-AML 2004

Ditte J. A. Løhmann, Jonas Abrahamsson, Shau-Yin Ha, Ólafur G. Jónsson, Minna Koskenvuo, Birgitte Lausen, Josefine Palle, Bernward Zeller, Henrik Hasle

https://doi.org/10.3324/haematol.2016.146175

Acute Lymphoblastic Leukemia

Non-Hodgkin Lymphoma

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis

Kebria Hezaveh, Andreas Kloetgen, Stephan H Bernhart, Kunal Das Mahapatra, Dido Lenze, Julia Richter, Andrea Haake, Anke K Bergmann, Benedikt Brors, Birgit Burkhardt, Alexander Claviez, Hans G Drexler, Roland Eils, Siegfried Haas, Steve Hoffmann, Dennis Karsch, Wolfram Klapper, Kortine Kleinheinz, Jan Korbel, Helene Kretzmer, Markus Kreuz, Ralf Küppers, Chris Lawerenz, Ellen Leich, Markus Loeffler, Luisa Mantovani-Loeffler, Cristina López, Alice C McHardy, Peter Möller, Marius Rohde, Philip Rosenstiel, Andreas Rosenwald, Markus Schilhabel, Matthias Schlesner, Ingrid Scholz, Peter F Stadler, Stephan Stilgenbauer, Stéphanie Sungalee, Monika Szczepanowski, Lorenz Trümper, Marc A Weniger, Reiner Siebert, Arndt Borkhardt, Michael Hummel, Jessica I. Hoell

https://doi.org/10.3324/haematol.2016.143891

Plasma Cell Disorders

Upfront autologous stem cell transplantation for newly diagnosed elderly multiple myeloma patients: a prospective multicenter study

Laurent Garderet, Eric Beohou, Denis Caillot, Anne Marie Stoppa, Cyrille Touzeau, Marie Lorraine Chretien, Lionel Karlin, Philippe Moreau, Jean Fontan, Didier Blaise, Emmanuelle Polge, Mor Seny Gueye, Souhila Ikhlef, Zora Marjanovic, Myriam Labopin, Mohamad Mohty

https://doi.org/10.3324/haematol.2016.150334

Cell Therapy and Immunotherapy

Autotransplant with and without induction chemotherapy in older multiple myeloma patients: long-term outcome of a randomized trial

Christian Straka, Peter Liebisch, Hans Salwender, Burkhard Hennemann, Bernd Metzner, Stefan Knop, Sigrid Adler-Reichel, Christian Gerecke, Hannes Wandt, Martin Bentz, Tim Hendrik Bruemmendorf, Marcus Hentrich, Michael Pfreundschuh, Hans-Heinrich Wolf, Orhan Sezer, Ralf Bargou, Wolfram Jung, Lorenz Trümper, Bernd Hertenstein, Else Heidemann, Helga Bernhard, Nicola Lang, Norbert Frickhofen, Holger Hebart, Ralf Schmidmaier, Andreas Sandermann, Tobias Dechow, Albrecht Reichle, Brigitte Schnabel, Kerstin Schäfer-Eckart, Christian Langer, Martin Gramatzki, Axel Hinke, Bertold Emmerich, Hermann Einsele

https://doi.org/10.3324/haematol.2016.151860

Splenic pooling and loss of VCAM-1 causes an engraftment defect in patients with myelofibrosis after allogeneic hematopoietic stem cell transplantation

Christina Hart, Sabine Klatt, Johann Barop, Gunnar Müller, Roland Schelker, Ernst Holler, Elisabeth Huber, Wolfgang Herr, Jochen Grassinger

https://doi.org/10.3324/haematol.2016.146811

The prognostic value of serum C-reactive protein, ferritin, and albumin prior to allogeneic transplantation for acute myeloid leukemia and myelodysplastic syndromes

Andrew S. Artz, Brent Logan, Xiaochun Zhu, Gorgun Akpek, Rodrigo Martino Bufarull, Vikas Gupta, Hillard M. Lazarus, Mark Litzow, Alison Loren, Navneet S. Majhail, Richard T. Maziarz, Philip McCarthy, Uday Popat, Wael Saber, Stephen Spellman, Olle Ringden, Amittha Wickrema, Marcelo C. Pasquini, Kenneth R. Cooke

https://doi.org/10.3324/haematol.2016.145847

A score of low-grade inflammation and risk of mortality: prospective findings from the Moli-sani study

Marialaura Bonaccio, Augusto Di Castelnuovo, George Pounis, Amalia De Curtis, Simona Costanzo, Mariarosaria Persichillo, Chiara Cerletti, Maria Benedetta Donati, Giovanni de Gaetano, Licia Iacoviello

https://doi.org/10.3324/haematol.2016.144055

Online Only Articles

Mutating heme oxygenase-1 into a peroxidase causes a defect in bilirubin synthesis associated with microcytic anemia and severe hyperinflammation

Johann Greil, Maria V. Verga-Falzacappa, Nicole E. Echner, Wolfgang Behnisch, Obul R. Bandapalli, Paulina Pechanska, Stephan Immenschuh, Vijith Vijayan, Jozsef Balla, Hirokatsu Tsukahara, Marion Schneider, Gritta Janka, Maren Claus, Thomas Longerich, Martina U. Muckenthaler, Andreas E. Kulozik

https://doi.org/10.3324/haematol.2016.147090

BNIP3L in myelodysplastic syndromes and acute myeloid leukemia: impact on disease outcome and cellular response to decitabine

Mariana Lazarini, João Agostinho Machado-Neto, Adriana da Silva Santos Duarte, Fernando Vieira Pericole, Karla Priscila Vieira, Fernanda S. Niemann, Marisa Alvarez, Fabiola Traina, Sara Teresinha Olalla Saad

https://doi.org/10.3324/haematol.2016.142521

Erlotinib synergizes with the poly(ADP-ribose) glycohydrolase inhibitor ethacridine in acute myeloid leukemia cells

Lianne E. Rotin, Neil MacLean, Ahmed Aman, Marcela Gronda, Feng-Hsu Lin, Rose Hurren, XiaoMing Wang, Jeffrey L Wrana, Alessandro Datti, Rima Al-awar, Mark D. Minden, Aaron D. Schimmer

https://doi.org/10.3324/haematol.2016.146894

MicroRNA expression-based outcome prediction in acute myeloid leukemia: novel insights through cross-platform integrative analyses

Velizar Shivarov, Anna Dolnik, Katharina M. Lang, Jan Krönke, Florian Kuchenbauer, Peter Paschka, Verena I. Gaidzik, Hartmut Döhner, Richard F. Schlenk, Konstanze Döhner, Lars Bullinger

https://doi.org/10.3324/haematol.2016.146555

Mutational correlates of response to hypomethylating agent therapy in acute myeloid leukemia

Catherine C. Coombs, David A. Sallman, Sean M. Devlin, Shweta Dixit, Abhinita Mohanty, Kristina Knapp, Najla H. Al Ali, Jeffrey E. Lancet, Alan F. List, Rami S. Komrokji, Eric Padron, Maria E. Arcila, Virginia M. Klimek, Marcel R. M. van den Brink, Martin S. Tallman, Ross L. Levine, Raajit K. Rampal, Franck Rapaport

https://doi.org/10.3324/haematol.2016.148999

Innate lymphoid cells are expanded and functionally altered in chronic lymphocytic leukemia

Iris de Weerdt, Vera van Hoeven, J. Marius Munneke, Sanne Endstra, Tom Hofland, Mette D. Hazenberg, Arnon P. Kater

https://doi.org/10.3324/haematol.2016.144725

Cytomegalovirus viremia, disease, and impact on relapse in T-cell replete peripheral blood haploidentical hematopoietic cell transplantation with post-transplant cyclophosphamide

Scott R. Goldsmith, Michael Slade, John F. DiPersio, Peter Westervelt, Steven J. Lawrence, Geoffrey L. Uy, Camille N. Abboud, Ravi Vij, Mark A. Schroeder, Todd A. Fehniger, Erik R. Dubberke, Kathryn Trinkaus, Rizwan Romee

https://doi.org/10.3324/haematol.2016.149880