Vol. 101 No. 10 (2016): October, 2016

The complex relationship of Tribbles pseudokinase 1, PML/RARA and C/EBPα in leukemia: two possible couples but not a trio (853 Online Views)

Guillermo Velasco

https://doi.org/10.3324/haematol.2016.151654

Matching inside and outside the HLA molecule in allogeneic hematopoietic stem cell transplantation (470 Online Views)

J. Alejandro Madrigal, Linda D. Barber

https://doi.org/10.3324/haematol.2016.150995

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice (5691 Online Views)

Celalettin Ustun, Michel Arock, Hanneke C. Kluin-Nelemans, Andreas Reiter, Wolfgang R. Sperr, Tracy George, Hans-Peter Horny, Karin Hartmann, Karl Sotlar, Gandhi Damaj, Olivier Hermine, Srdan Verstovsek, Dean D. Metcalfe, Jason Gotlib, Cem Akin, Peter Valent

https://doi.org/10.3324/haematol.2016.146563

Catching up with solid tumor oncology: what is the evidence for a prognostic role of programmed cell death-ligand 1/programmed cell death-1 expression in B-cell lymphomas? (1224 Online Views)

Fabienne McClanahan, Thomas G. Sharp, John G. Gribben

https://doi.org/10.3324/haematol.2016.145904

A population pharmacokinetic model for perioperative dosing of factor VIII in hemophilia A patients (1309 Online Views)

Hendrika Hazendonk, Karin Fijnvandraat, Janske Lock, Mariëtte Driessens, Felix van der Meer, Karina Meijer, Marieke Kruip, Britta Laros-van Gorkom, Marjolein Peters, Saskia de Wildt, Frank Leebeek, Marjon Cnossen, Ron Mathôt

https://doi.org/10.3324/haematol.2015.136275

Whole exome sequencing identifies genetic variants in inherited thrombocytopenia with secondary qualitative function defects (2362 Online Views)

Ben Johnson, Gillian C. Lowe, Jane Futterer, Marie Lordkipanidzé, David MacDonald, Michael A. Simpson, Isabel Sanchez-Guiú, Sian Drake, Danai Bem, Vincenzo Leo, Sarah J. Fletcher, Ban Dawood, José Rivera, David Allsup, Tina Biss, Paula HB Bolton-Maggs, Peter Collins, Nicola Curry, Charlotte Grimley, Beki James, Mike Makris, Jayashree Motwani, Sue Pavord, Katherine Talks, Jecko Thachil, Jonathan Wilde, Mike Williams, Paul Harrison, Paul Gissen, Stuart Mundell, Andrew Mumford, Martina E. Daly, Steve P. Watson, Neil V. Morgan

https://doi.org/10.3324/haematol.2016.146316

Marked overlap of four genetic syndromes with dyskeratosis congenita confounds clinical diagnosis (1713 Online Views)

Amanda J. Walne, Laura Collopy, Shirleny Cardoso, Alicia Ellison, Vincent Plagnol, Canan Albayrak, Davut Albayrak, Sara Sebnem Kilic, Turkan Patıroglu, Haluk Akar, Keith Godfrey, Tina Carter, Makia Marafie, Ajay Vora, Mikael Sundin, Thomas Vulliamy, Hemanth Tummala, Inderjeet Dokal

https://doi.org/10.3324/haematol.2016.147769

Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency (1527 Online Views)

Zohar Sachs, Raha A. Been, Krista J. DeCoursin, Hanh T. Nguyen, Nurul A. Mohd Hassan, Klara E. Noble-Orcutt, Craig E. Eckfeldt, Emily J. Pomeroy, Ernesto Diaz-Flores, Jennifer L. Geurts, Miechaleen D. Diers, Diane E. Hasz, Kelly J. Morgan, Margaret L. MacMillan, Kevin M. Shannon, David A. Largaespada, Stephen M. Wiesner

https://doi.org/10.3324/haematol.2015.136002

Nilotinib 300 mg twice daily: an academic single-arm study of newly diagnosed chronic phase chronic myeloid leukemia patients (1246 Online Views)

Fausto Castagnetti, Massimo Breccia, Gabriele Gugliotta, Bruno Martino, Mariella D’Adda, Fabio Stagno, Angelo Michele Carella, Paolo Avanzini, Mario Tiribelli, Elena Trabacchi, Giuseppe Visani, Marco Gobbi, Marzia Salvucci, Luciano Levato, Gianni Binotto, Silvana Franca Capalbo, Maria Teresa Bochicchio, Simona Soverini, Michele Cavo, Giovanni Martinelli, Giuliana Alimena, Fabrizio Pane, Giuseppe Saglio, Gianantonio Rosti, Michele Baccarani

https://doi.org/10.3324/haematol.2016.144949

Ciprofloxacin versus colistin prophylaxis during neutropenia in acute myeloid leukemia: two parallel patient cohorts treated in a single center (1525 Online Views)

Michele Pohlen, Julia Marx, Alexander Mellmann, Karsten Becker, Rolf M. Mesters, Jan-Henrik Mikesch, Christoph Schliemann, Georg Lenz, Carsten Müller-Tidow, Thomas Büchner, Utz Krug, Matthias Stelljes, Helge Karch, Georg Peters, Hans U. Gerth, Dennis Görlich, Wolfgang E. Berdel

https://doi.org/10.3324/haematol.2016.147934

Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner (3733 Online Views)

Yahya S. Al-Matary, Lacramioara Botezatu, Bertram Opalka, Judith M. Hönes, Robert F. Lams, Aniththa Thivakaran, Judith Schütte, Renata Köster, Klaus Lennartz, Thomas Schroeder, Rainer Haas, Ulrich Dührsen, Cyrus Khandanpour

https://doi.org/10.3324/haematol.2016.143180

Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA (1652 Online Views)

Karen Keeshan, Pauline Vieugué, Shahzya Chaudhury, Loveena Rishi, Coline Gaillard, Lu Liang, Elaine Garcia, Takuro Nakamura, Nader Omidvar, Scott C. Kogan

https://doi.org/10.3324/haematol.2015.138503

Definition of bulky disease in early stage Hodgkin lymphoma in computed tomography era: prognostic significance of measurements in the coronal and transverse planes (11920 Online Views)

Anita Kumar, Irene A. Burger, Zhigang Zhang, Esther N. Drill, Jocelyn C. Migliacci, Andrea Ng, Ann LaCasce, Darci Wall, Thomas E. Witzig, Kay Ristow, Joachim Yahalom, Craig H. Moskowitz, Andrew D. Zelenetz

https://doi.org/10.3324/haematol.2016.141846

Non-Hodgkin lymphoma in the developing world: review of 4539 cases from the International Non-Hodgkin Lymphoma Classification Project (3901 Online Views)

Anamarija M. Perry, Jacques Diebold, Bharat N. Nathwani, Kenneth A. MacLennan, Hans K. Müller-Hermelink, Martin Bast, Eugene Boilesen, James O. Armitage, Dennis D. Weisenburger

https://doi.org/10.3324/haematol.2016.148809

A phase I study of CD25/regulatory T-cell-depleted donor lymphocyte infusion for relapse after allogeneic stem cell transplantation (1060 Online Views)

Sarah Nikiforow, Haesook T. Kim, Heather Daley, Carol Reynolds, Kyle Thomas Jones, Philippe Armand, Vincent T. Ho, Edwin P. Alyea, Corey S. Cutler, Jerome Ritz, Joseph H. Antin, Robert J. Soiffer, John Koreth

https://doi.org/10.3324/haematol.2015.141176

Donor and recipient sex in allogeneic stem cell transplantation: what really matters (2038 Online Views)

Haesook T. Kim, Mei-Jie Zhang, Ann E. Woolfrey, Andrew St. Martin, Junfang Chen, Wael Saber, Miguel-Angel Perales, Philippe Armand, Mary Eapen

https://doi.org/10.3324/haematol.2016.147645

Human leukocyte antigen supertype matching after myeloablative hematopoietic cell transplantation with 7/8 matched unrelated donor allografts: a report from the Center for International Blood and Marrow Transplant Research (1473 Online Views)

Aleksandr Lazaryan, Tao Wang, Stephen R. Spellman, Hai-Lin Wang, Joseph Pidala, Taiga Nishihori, Medhat Askar, Richard Olsson, Machteld Oudshoorn, Hisham Abdel-Azim, Agnes Yong, Manish Gandhi, Christopher Dandoy, Bipin Savani, Gregory Hale, Kristin Page, Menachem Bitan, Ran Reshef, William Drobyski, Steven GE Marsh, Kirk Schultz, Carlheinz R. Müller, Marcelo A. Fernandez-Viña, Michael R. Verneris, Mary M. Horowitz, Mukta Arora, Daniel J. Weisdorf, Stephanie J. Lee

https://doi.org/10.3324/haematol.2016.143271

Specific antibody deficiency and autoinflammatory disease extend the clinical and immunological spectrum of heterozygous NFKB1 loss-of-function mutations in humans (1887 Online Views)

Cyrill Schipp, Schafiq Nabhani, Kirsten Bienemann, Natalia Simanovsky, Shlomit Kfir-Erenfeld, Nathalie Assayag-Asherie, Prasad T. Oommen, Shoshana Revel-Vilk, Andrea Hönscheid, Michael Gombert, Sebastian Ginzel, Daniel Schäfer, Hans-Jürgen Laws, Eitan Yefenof, Bernhard Fleckenstein, Arndt Borkhardt, Polina Stepensky, Ute Fischer

https://doi.org/10.3324/haematol.2016.145136

Genetic inactivation of calpain-1 attenuates pain sensitivity in a humanized mouse model of sickle cell disease (686 Online Views)

Jennifer O. Nwankwo, Jianxun Lei, Jian Xu, Alicia Rivera, Kalpna Gupta, Athar H. Chishti

https://doi.org/10.3324/haematol.2016.148106

Neutrophil to lymphocyte ratio and future risk of venous thromboembolism and mortality: the Tromsø Study (946 Online Views)

Gro Grimnes, Lars D. Horvei, Vladimir Tichelaar, Sigrid K. Brækkan, John-Bjarne Hansen

https://doi.org/10.3324/haematol.2016.145151

Discrepancies of applying primary myelofibrosis prognostic scores for patients with post polycythemia vera/essential thrombocytosis myelofibrosis (9186 Online Views)

Krisstina Gowin, Maria Coakley, Heidi Kosiorek, Ruben Mesa

https://doi.org/10.3324/haematol.2016.149013

European phase II study of mogamulizumab, an anti-CCR4 monoclonal antibody, in relapsed/refractory peripheral T-cell lymphoma (1129 Online Views)

Pier Luigi Zinzani, Lionel Karlin, John Radford, Dolores Caballero, Paul Fields, Martine E. D. Chamuleau, Francesco d’Amore, Corinne Haioun, Catherine Thieblemont, Eva González-Barca, Carlos Grande García, Peter W. Johnson, Gustaaf W. van Imhoff, Thomas Ng, Karen Dwyer, Franck Morschhauser

https://doi.org/10.3324/haematol.2016.146977

Maintenance rituximab following induction R-CHOP chemotherapy in patients with composite or discordant, indolent and aggressive, B-cell non-Hodgkin lymphomas (921 Online Views)

Roopesh Kansara, Joseph M. Connors, Kerry J. Savage, Alina S. Gerrie, David W. Scott, Graham W. Slack, Randy D. Gascoyne, Laurie H. Sehn, Diego Villa

https://doi.org/10.3324/haematol.2016.144550

Baseline bone involvement in multiple myeloma – a prospective comparison of conventional X-ray, low-dose computed tomography, and 18flourodeoxyglucose positron emission tomography in previously untreated patients (1809 Online Views)

Maja Hinge, Kristian T. Andersen, Thomas Lund, Henrik B. Jørgensen, Paw C. Holdgaard, Tina E. Ormstrup, Lone L. Østergaard, Torben Plesner

https://doi.org/10.3324/haematol.2016.146092

Bone healing in multiple myeloma: a prospective evaluation of the impact of first-line anti-myeloma treatment (1248 Online Views)

Maja Hinge, Kristian T Andersen, Thomas Lund, Henrik B Jørgensen, Paw C Holdgaard, Tina E Ormstrup, Lone L Østergaard, Torben Plesner

https://doi.org/10.3324/haematol.2016.144477

Identification of a new potential mechanism responsible for severe bleeding in myeloma: immunoglobulins bind the heparin binding domain of antithrombin activating this endogenous anticoagulant (921 Online Views)

Irene Martínez-Martínez, José Ramón González-Porras, María José Cebeira, Felipe de Arriba, Salvador Espín, Nataliya Bohdan, Fernando José Corrales, Javier Corral, Vicente Vicente

https://doi.org/10.3324/haematol.2016.144873