October, 2016
No. 101 (10)

Editorials

Review Articles

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice (5740 Online Views)

Celalettin Ustun, Michel Arock, Hanneke C. Kluin-Nelemans, Andreas Reiter, Wolfgang R. Sperr, Tracy George, Hans-Peter Horny, Karin Hartmann, Karl Sotlar, Gandhi Damaj, Olivier Hermine, Srdan Verstovsek, Dean D. Metcalfe, Jason Gotlib, Cem Akin, Peter Valent

https://doi.org/10.3324/haematol.2016.146563

Articles

Coagulation & its Disorders

A population pharmacokinetic model for perioperative dosing of factor VIII in hemophilia A patients (1319 Online Views)

Hendrika Hazendonk, Karin Fijnvandraat, Janske Lock, Mariëtte Driessens, Felix van der Meer, Karina Meijer, Marieke Kruip, Britta Laros-van Gorkom, Marjolein Peters, Saskia de Wildt, Frank Leebeek, Marjon Cnossen, Ron Mathôt

https://doi.org/10.3324/haematol.2015.136275

Platelet Biology & its Disorders

Whole exome sequencing identifies genetic variants in inherited thrombocytopenia with secondary qualitative function defects (2389 Online Views)

Ben Johnson, Gillian C. Lowe, Jane Futterer, Marie Lordkipanidzé, David MacDonald, Michael A. Simpson, Isabel Sanchez-Guiú, Sian Drake, Danai Bem, Vincenzo Leo, Sarah J. Fletcher, Ban Dawood, José Rivera, David Allsup, Tina Biss, Paula HB Bolton-Maggs, Peter Collins, Nicola Curry, Charlotte Grimley, Beki James, Mike Makris, Jayashree Motwani, Sue Pavord, Katherine Talks, Jecko Thachil, Jonathan Wilde, Mike Williams, Paul Harrison, Paul Gissen, Stuart Mundell, Andrew Mumford, Martina E. Daly, Steve P. Watson, Neil V. Morgan

https://doi.org/10.3324/haematol.2016.146316

Bone Marrow Failure

Marked overlap of four genetic syndromes with dyskeratosis congenita confounds clinical diagnosis (1728 Online Views)

Amanda J. Walne, Laura Collopy, Shirleny Cardoso, Alicia Ellison, Vincent Plagnol, Canan Albayrak, Davut Albayrak, Sara Sebnem Kilic, Turkan Patıroglu, Haluk Akar, Keith Godfrey, Tina Carter, Makia Marafie, Ajay Vora, Mikael Sundin, Thomas Vulliamy, Hemanth Tummala, Inderjeet Dokal

https://doi.org/10.3324/haematol.2016.147769

Myeloproliferative Disorders

Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency (1543 Online Views)

Zohar Sachs, Raha A. Been, Krista J. DeCoursin, Hanh T. Nguyen, Nurul A. Mohd Hassan, Klara E. Noble-Orcutt, Craig E. Eckfeldt, Emily J. Pomeroy, Ernesto Diaz-Flores, Jennifer L. Geurts, Miechaleen D. Diers, Diane E. Hasz, Kelly J. Morgan, Margaret L. MacMillan, Kevin M. Shannon, David A. Largaespada, Stephen M. Wiesner

https://doi.org/10.3324/haematol.2015.136002

Chronic Myeloid Leukemia

Nilotinib 300 mg twice daily: an academic single-arm study of newly diagnosed chronic phase chronic myeloid leukemia patients (1251 Online Views)

Fausto Castagnetti, Massimo Breccia, Gabriele Gugliotta, Bruno Martino, Mariella D’Adda, Fabio Stagno, Angelo Michele Carella, Paolo Avanzini, Mario Tiribelli, Elena Trabacchi, Giuseppe Visani, Marco Gobbi, Marzia Salvucci, Luciano Levato, Gianni Binotto, Silvana Franca Capalbo, Maria Teresa Bochicchio, Simona Soverini, Michele Cavo, Giovanni Martinelli, Giuliana Alimena, Fabrizio Pane, Giuseppe Saglio, Gianantonio Rosti, Michele Baccarani

https://doi.org/10.3324/haematol.2016.144949

Acute Myeloid Leukemia

Ciprofloxacin versus colistin prophylaxis during neutropenia in acute myeloid leukemia: two parallel patient cohorts treated in a single center (1535 Online Views)

Michele Pohlen, Julia Marx, Alexander Mellmann, Karsten Becker, Rolf M. Mesters, Jan-Henrik Mikesch, Christoph Schliemann, Georg Lenz, Carsten Müller-Tidow, Thomas Büchner, Utz Krug, Matthias Stelljes, Helge Karch, Georg Peters, Hans U. Gerth, Dennis Görlich, Wolfgang E. Berdel

https://doi.org/10.3324/haematol.2016.147934

Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner (3768 Online Views)

Yahya S. Al-Matary, Lacramioara Botezatu, Bertram Opalka, Judith M. Hönes, Robert F. Lams, Aniththa Thivakaran, Judith Schütte, Renata Köster, Klaus Lennartz, Thomas Schroeder, Rainer Haas, Ulrich Dührsen, Cyrus Khandanpour

https://doi.org/10.3324/haematol.2016.143180

Co-operative leukemogenesis in acute myeloid leukemia and acute promyelocytic leukemia reveals C/EBPα as a common target of TRIB1 and PML/RARA (1658 Online Views)

Karen Keeshan, Pauline Vieugué, Shahzya Chaudhury, Loveena Rishi, Coline Gaillard, Lu Liang, Elaine Garcia, Takuro Nakamura, Nader Omidvar, Scott C. Kogan

https://doi.org/10.3324/haematol.2015.138503

Hodgkin Lymphoma

Definition of bulky disease in early stage Hodgkin lymphoma in computed tomography era: prognostic significance of measurements in the coronal and transverse planes (11941 Online Views)

Anita Kumar, Irene A. Burger, Zhigang Zhang, Esther N. Drill, Jocelyn C. Migliacci, Andrea Ng, Ann LaCasce, Darci Wall, Thomas E. Witzig, Kay Ristow, Joachim Yahalom, Craig H. Moskowitz, Andrew D. Zelenetz

https://doi.org/10.3324/haematol.2016.141846

Non-Hodgkin Lymphoma

Non-Hodgkin lymphoma in the developing world: review of 4539 cases from the International Non-Hodgkin Lymphoma Classification Project (3960 Online Views)

Anamarija M. Perry, Jacques Diebold, Bharat N. Nathwani, Kenneth A. MacLennan, Hans K. Müller-Hermelink, Martin Bast, Eugene Boilesen, James O. Armitage, Dennis D. Weisenburger

https://doi.org/10.3324/haematol.2016.148809

Cell Therapy & Immunotherapy

A phase I study of CD25/regulatory T-cell-depleted donor lymphocyte infusion for relapse after allogeneic stem cell transplantation (1084 Online Views)

Sarah Nikiforow, Haesook T. Kim, Heather Daley, Carol Reynolds, Kyle Thomas Jones, Philippe Armand, Vincent T. Ho, Edwin P. Alyea, Corey S. Cutler, Jerome Ritz, Joseph H. Antin, Robert J. Soiffer, John Koreth

https://doi.org/10.3324/haematol.2015.141176

Donor and recipient sex in allogeneic stem cell transplantation: what really matters (2062 Online Views)

Haesook T. Kim, Mei-Jie Zhang, Ann E. Woolfrey, Andrew St. Martin, Junfang Chen, Wael Saber, Miguel-Angel Perales, Philippe Armand, Mary Eapen

https://doi.org/10.3324/haematol.2016.147645

Human leukocyte antigen supertype matching after myeloablative hematopoietic cell transplantation with 7/8 matched unrelated donor allografts: a report from the Center for International Blood and Marrow Transplant Research (1484 Online Views)

Aleksandr Lazaryan, Tao Wang, Stephen R. Spellman, Hai-Lin Wang, Joseph Pidala, Taiga Nishihori, Medhat Askar, Richard Olsson, Machteld Oudshoorn, Hisham Abdel-Azim, Agnes Yong, Manish Gandhi, Christopher Dandoy, Bipin Savani, Gregory Hale, Kristin Page, Menachem Bitan, Ran Reshef, William Drobyski, Steven GE Marsh, Kirk Schultz, Carlheinz R. Müller, Marcelo A. Fernandez-Viña, Michael R. Verneris, Mary M. Horowitz, Mukta Arora, Daniel J. Weisdorf, Stephanie J. Lee

https://doi.org/10.3324/haematol.2016.143271

Online Only Articles

Specific antibody deficiency and autoinflammatory disease extend the clinical and immunological spectrum of heterozygous NFKB1 loss-of-function mutations in humans (1893 Online Views)

Cyrill Schipp, Schafiq Nabhani, Kirsten Bienemann, Natalia Simanovsky, Shlomit Kfir-Erenfeld, Nathalie Assayag-Asherie, Prasad T. Oommen, Shoshana Revel-Vilk, Andrea Hönscheid, Michael Gombert, Sebastian Ginzel, Daniel Schäfer, Hans-Jürgen Laws, Eitan Yefenof, Bernhard Fleckenstein, Arndt Borkhardt, Polina Stepensky, Ute Fischer

https://doi.org/10.3324/haematol.2016.145136

European phase II study of mogamulizumab, an anti-CCR4 monoclonal antibody, in relapsed/refractory peripheral T-cell lymphoma (1144 Online Views)

Pier Luigi Zinzani, Lionel Karlin, John Radford, Dolores Caballero, Paul Fields, Martine E. D. Chamuleau, Francesco d’Amore, Corinne Haioun, Catherine Thieblemont, Eva González-Barca, Carlos Grande García, Peter W. Johnson, Gustaaf W. van Imhoff, Thomas Ng, Karen Dwyer, Franck Morschhauser

https://doi.org/10.3324/haematol.2016.146977

Bone healing in multiple myeloma: a prospective evaluation of the impact of first-line anti-myeloma treatment (1261 Online Views)

Maja Hinge, Kristian T Andersen, Thomas Lund, Henrik B Jørgensen, Paw C Holdgaard, Tina E Ormstrup, Lone L Østergaard, Torben Plesner

https://doi.org/10.3324/haematol.2016.144477

Identification of a new potential mechanism responsible for severe bleeding in myeloma: immunoglobulins bind the heparin binding domain of antithrombin activating this endogenous anticoagulant (928 Online Views)

Irene Martínez-Martínez, José Ramón González-Porras, María José Cebeira, Felipe de Arriba, Salvador Espín, Nataliya Bohdan, Fernando José Corrales, Javier Corral, Vicente Vicente

https://doi.org/10.3324/haematol.2016.144873