September, 2016
No. 101 (9)

Editorials

Review Articles

Clinical impact of recurrently mutated genes on lymphoma diagnostics: state-of-the-art and beyond

Richard Rosenquist, Andreas Rosenwald, Ming-Qing Du, Gianluca Gaidano, Patricia Groenen, Andrew Wotherspoon, Paolo Ghia, Philippe Gaulard, Elias Campo, Kostas Stamatopoulos

https://doi.org/10.3324/haematol.2015.134510

Articles

Red Cell Biology & Its Disorders

Severe Ankyrin-R deficiency results in impaired surface retention and lysosomal degradation of RhAG in human erythroblasts

Timothy J. Satchwell, Amanda J. Bell, Bethan R. Hawley, Stephanie Pellegrin, Kathryn E. Mordue, Cees Th. B. M. van Deursen, Nicole Heitink-ter Braak, Gerwin Huls, Mathie P.G Leers, Eline Overwater, Rienk Y. J. Tamminga, Bert van der Zwaag, Elisa Fermo, Paola Bianchi, Richard van Wijk, Ashley M. Toye

https://doi.org/10.3324/haematol.2016.146209

Altered heme-mediated modulation of dendritic cell function in sickle cell alloimmunization

Emmanuelle Godefroy, Yunfeng Liu, Patricia Shi, W. Beau Mitchell, Devin Cohen, Stella T. Chou, Deepa Manwani, Karina Yazdanbakhsh

https://doi.org/10.3324/haematol.2016.147181

Platelet Biology & its Disorders

Immune thrombocytopenia in adults: a prospective cohort study of clinical features and predictors of outcome

Lamiae Grimaldi-Bensouda, Clémentine Nordon, Marc Michel, Jean-François Viallard, Daniel Adoue, Nadine Magy-Bertrand, Jean-Marc Durand, Philippe Quittet, Olivier Fain, Bernard Bonnotte, Anne-Sophie Morin, Nathalie Morel, Nathalie Costedoat-Chalumeau, Brigitte Pan-Petesch, Mehdi Khellaf, Antoinette Perlat, Karim Sacre, François Lefrere, Lucien Abenhaim, Bertrand Godeau

https://doi.org/10.3324/haematol.2016.146373

Coagulation & Its Disorders

Joint effects of cancer and variants in the factor 5 gene on the risk of venous thromboembolism

Olga V. Gran, Erin N. Smith, Sigrid K. Brækkan, Hilde Jensvoll, Terry Solomon, Kristian Hindberg, Tom Wilsgaard, Frits R. Rosendaal, Kelly A. Frazer, John-Bjarne Hansen

https://doi.org/10.3324/haematol.2016.147405

Myeloproliferative Disorders

Safety and efficacy of ruxolitinib in an open-label, multicenter, single-arm phase 3b expanded-access study in patients with myelofibrosis: a snapshot of 1144 patients in the JUMP trial

Haifa Kathrin Al-Ali, Martin Griesshammer, Philipp le Coutre, Cornelius F. Waller, Anna Marina Liberati, Philippe Schafhausen, Renato Tavares, Pilar Giraldo, Lynda Foltz, Pia Raanani, Vikas Gupta, Bayane Tannir, Julian Perez Ronco, Jagannath Ghosh, Bruno Martino, Alessandro M. Vannucchi

https://doi.org/10.3324/haematol.2016.143677

Acute Myeloid Leukemia

Clinical characteristics and prognosis of acute myeloid leukemia associated with DNA-methylation regulatory gene mutations

Takeshi Ryotokuji, Hiroki Yamaguchi, Toshimitsu Ueki, Kensuke Usuki, Saiko Kurosawa, Yutaka Kobayashi, Eri Kawata, Kenji Tajika, Seiji Gomi, Junya Kanda, Anna Kobayashi, Ikuko Omori, Atsushi Marumo, Yusuke Fujiwara, Shunsuke Yui, Kazuki Terada, Keiko Fukunaga, Tsuneaki Hirakawa, Kunihito Arai, Tomoaki Kitano, Fumiko Kosaka, Hayato Tamai, Kazutaka Nakayama, Satoshi Wakita, Takahiro Fukuda, Koiti Inokuchi

https://doi.org/10.3324/haematol.2016.143073

Acute Lymphoblastic Leukemia

Characterization of leukemias with ETV6-ABL1 fusion

Marketa Zaliova, Anthony V. Moorman, Giovanni Cazzaniga, Martin Stanulla, Richard C. Harvey, Kathryn G. Roberts, Sue L. Heatley, Mignon L. Loh, Marina Konopleva, I-Ming Chen, Olga Zimmermannova, Claire Schwab, Owen Smith, Marie-Joelle Mozziconacci, Christian Chabannon, Myungshin Kim, J. H. Frederik Falkenburg, Alice Norton, Karen Marshall, Oskar A. Haas, Julia Starkova, Jan Stuchly, Stephen P. Hunger, Deborah White, Charles G. Mullighan, Cheryl L. Willman, Jan Stary, Jan Trka, Jan Zuna

https://doi.org/10.3324/haematol.2016.144345

Hodgkin Lymphoma

Detection and prognostic value of recurrent exportin 1 mutations in tumor and cell-free circulating DNA of patients with classical Hodgkin lymphoma

Vincent Camus, Aspasia Stamatoullas, Sylvain Mareschal, Pierre-Julien Viailly, Nasrin Sarafan-Vasseur, Elodie Bohers, Sydney Dubois, Jean Michel Picquenot, Philippe Ruminy, Catherine Maingonnat, Philippe Bertrand, Marie Cornic, Valérie Tallon-Simon, Stéphanie Becker, Liana Veresezan, Thierry Frebourg, Pierre Vera, Christian Bastard, Hervé Tilly, Fabrice Jardin

https://doi.org/10.3324/haematol.2016.145102

Plasma Cell Disorders

Immunoparesis status in immunoglobulin light chain amyloidosis at diagnosis affects response and survival by regimen type

Eli Muchtar, Angela Dispenzieri, Shaji K. Kumar, David Dingli, Martha Q. Lacy, Francis K. Buadi, Suzanne R. Hayman, Prashant Kapoor, Nelson Leung, Rajshekhar Chakraborty, Stephen Russell, John A. Lust, Yi Lin, Ronald S. Go, Steven Zeldenrust, Robert A. Kyle, S. Vincent Rajkumar, Morie A. Gertz

https://doi.org/10.3324/haematol.2016.147041

Acute Lymphoblastic Leukemia

Geriatric assessment in multiple myeloma patients: validation of the International Myeloma Working Group (IMWG) score and comparison with other common comorbidity scores

Monika Engelhardt, Sandra Maria Dold, Gabriele Ihorst, Alexander Zober, Mandy Möller, Heike Reinhardt, Stefanie Hieke, Martin Schumacher, Ralph Wäsch

https://doi.org/10.3324/haematol.2016.148189

Stem Cell Transplantation

Outcomes of unrelated cord blood transplantation in patients with multiple myeloma: a survey on behalf of Eurocord, the Cord Blood Committee of Cellular Therapy and Immunobiology Working Party, and the Chronic Leukemia Working Party of the EBMT

Annalisa Paviglianiti, Erick Xavier, Annalisa Ruggeri, Patrice Ceballos, Eric Deconinck, Jan J. Cornelissen, Stephanie Nguyen-Quoc, Natacha Maillard, Guillermo Sanz, Pierre-Simon Rohrlich, Laurent Garderet, Fernanda Volt, Vanderson Rocha, Nicolaus Kroeger, Eliane Gluckman, Nathalie Fegueux, Mohamad Mohty

https://doi.org/10.3324/haematol.2015.138917

Online Only Articles

Efficacy estimation of erythropoiesis-stimulating agents using erythropoietin-deficient anemic mice

Norio Suzuki, Yusuke Sasaki, Koichiro Kato, Shun Yamazaki, Mitsue Kurasawa, Keigo Yorozu, Yasushi Shimonaka, Masayuki Yamamoto

https://doi.org/10.3324/haematol.2015.140814

Immunoglobulin heavy and light chain gene features are correlated with primary cold agglutinin disease onset and activity

Agnieszka Małecka, Gunhild Trøen, Anne Tierens, Ingunn Østlie, Jędrzej Małecki, Ulla Randen, Sigbjørn Berentsen, Geir E. Tjønnfjord, Jan M.A. Delabie

https://doi.org/10.3324/haematol.2016.146126

Microparticle phenotypes are associated with driver mutations and distinct thrombotic risks in essential thrombocythemia

Agnès Charpentier, Aurélien Lebreton, Antoine Rauch, Anne Bauters, Nathalie Trillot, Oliver Nibourel, Véronique Tintillier, Mathieu Wemeau, Jean-Loup Demory, Claude Preudhomme, Brigitte Jude, Thomas Lecompte, Nathalie Cambier, Sophie Susen

https://doi.org/10.3324/haematol.2016.144279

ATM mutations in major stereotyped subsets of chronic lymphocytic leukemia: enrichment in subset #2 is associated with markedly short telomeres

Veronika Navrkalova, Emma Young, Panagiotis Baliakas, Lenka Radova, Lesley-Ann Sutton, Karla Plevova, Larry Mansouri, Viktor Ljungström, Stavroula Ntoufa, Zadie Davis, Gunnar Juliusson, Karin E. Smedby, Chrysoula Belessi, Panagiotis Panagiotidis, Tasoula Touloumenidou, Frederic Davi, Anton W. Langerak, Paolo Ghia, Jonathan C. Strefford, David Oscier, Jiri Mayer, Kostas Stamatopoulos, Sarka Pospisilova, Richard Rosenquist, Martin Trbusek

https://doi.org/10.3324/haematol.2016.142968

Complementarity determining region-independent recognition of a superantigen by B-cell antigen receptors of mantle cell lymphoma

Michael Fichtner, Elmar Spies, Henning Seismann, Kristoffer Riecken, Niklas Engels, Barbara Gösch, Judith Dierlamm, Helwe Gerull, Peter Nollau, Wolfram Klapper, Martin Dreyling, Mascha Binder, Martin Trepel

https://doi.org/10.3324/haematol.2016.141929

Whole exome sequencing reveals activating JAK1 and STAT3 mutations in breast implant-associated anaplastic large cell lymphoma anaplastic large cell lymphoma

Piers Blombery, Ella R. Thompson, Kate Jones, Gisela Mir Arnau, Stephen Lade, John F. Markham, Jason Li, Anand Deva, Ricky W. Johnstone, Amit Khot, H. Miles Prince, David Westerman

https://doi.org/10.3324/haematol.2016.146118