Vol. 100 No. 6 (2015): June, 2015

The ins and outs of erythroid heme transport (535 Online Views)

Chang Cao, Mark D. Fleming

https://doi.org/10.3324/haematol.2015.127886

Health-related quality of life in patients with multiple myeloma - does it matter? (1035 Online Views)

Ann Kristin Kvam, Anders Waage

https://doi.org/10.3324/haematol.2015.127860

Personalized medicine in lymphoma: is it worthwhile? The mantle cell lymphoma experience (540 Online Views)

Martin Dreyling, Simone Ferrero

https://doi.org/10.3324/haematol.2015.127472

T-cell and natural killer cell therapies for hematologic malignancies after hematopoietic stem cell transplantation: enhancing the graft-versus-leukemia effect (3406 Online Views)

C. Russell Cruz, Catherine M. Bollard

https://doi.org/10.3324/haematol.2014.113860

Erythroblast apoptosis and microenvironmental iron restriction trigger anemia in the VK*MYC model of multiple myeloma (1133 Online Views)

Jessica Bordini, Maria Teresa Sabrina Bertilaccio, Maurilio Ponzoni, Isabella Fermo, Marta Chesi, P. Leif Bergsagel, Clara Camaschella, Alessandro Campanella

https://doi.org/10.3324/haematol.2014.118000

The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation (1261 Online Views)

Sonia Mercurio, Sara Petrillo, Deborah Chiabrando, Zuni Irma Bassi, Dafne Gays, Annalisa Camporeale, Andrei Vacaru, Barbara Miniscalco, Giulio Valperga, Lorenzo Silengo, Fiorella Altruda, Margaret H. Baron, Massimo Mattia Santoro, Emanuela Tolosano

https://doi.org/10.3324/haematol.2014.114488

Key endothelial cell angiogenic mechanisms are stimulated by the circulating milieu in sickle cell disease and attenuated by hydroxyurea (1000 Online Views)

Flavia C. M. Lopes, Fabiola Traina, Camila B. Almeida, Flavia C. Leonardo, Carla F. Franco-Penteado, Vanessa T. Garrido, Marina P. Colella, Raquel Soares, Sara T. Olalla-Saad, Fernando F. Costa, Nicola Conran

https://doi.org/10.3324/haematol.2014.119727

Risk of bleeding and use of platelet transfusions in patients with hematologic malignancies: recurrent event analysis (1469 Online Views)

Simon J. Stanworth, Cara L. Hudson, Lise J. Estcourt, Rachel J. Johnson, Erica M. Wood

https://doi.org/10.3324/haematol.2014.118075

Rate-limiting roles of the tenase complex of factors VIII and IX in platelet procoagulant activity and formation of platelet-fibrin thrombi under flow (1050 Online Views)

Frauke Swieringa, Marijke J. E. Kuijpers, Moniek M. E. Lamers, Paola E. J. van der Meijden, Johan W. M. Heemskerk

https://doi.org/10.3324/haematol.2014.116863

Tetraspanin CD9 participates in dysmegakaryopoiesis and stromal interactions in primary myelofibrosis (1165 Online Views)

Christophe Desterke, Christophe Martinaud, Bernadette Guerton, Lisa Pieri, Costanza Bogani, Denis Clay, Frederic Torossian, Jean-Jacques Lataillade, Hans C. Hasselbach, Heinz Gisslinger, Jean-Loup Demory, Brigitte Dupriez, Claude Boucheix, Eric Rubinstein, Sophie Amsellem, Alessandro M. Vannucchi, Marie-Caroline Le Bousse-Kerdilès

https://doi.org/10.3324/haematol.2014.118497

CD133 marks a stem cell population that drives human primary myelofibrosis (1468 Online Views)

Ioanna Triviai, Thomas Stübig, Birte Niebuhr, Kais Hussein, Asterios Tsiftsoglou, Boris Fehse, Carol Stocking, Nicolaus Kröger

https://doi.org/10.3324/haematol.2014.118463

Dasatinib in high-risk core binding factor acute myeloid leukemia in first complete remission: a French Acute Myeloid Leukemia Intergroup trial (1143 Online Views)

Nicolas Boissel, Aline Renneville, Thibaut Leguay, Pascale Cornillet Lefebvre, Christian Recher, Thibaud Lecerf, Eric Delabesse, Céline Berthon, Odile Blanchet, Thomas Prebet, Cécile Pautas, Patrice Chevallier, Stéphane Leprêtre, Stéphane Girault, Caroline Bonmati, Romain Guièze, Chantal Himberlin, Edouard Randriamalala, Claude Preudhomme, Eric Jourdan, Hervé Dombret, Norbert Ifrah

https://doi.org/10.3324/haematol.2014.114884

Randomized trial of radiation-free central nervous system prophylaxis comparing intrathecal triple therapy with liposomal cytarabine in acute lymphoblastic leukemia (1422 Online Views)

Renato Bassan, Arianna Masciulli, Tamara Intermesoli, Ernesta Audisio, Giuseppe Rossi, Enrico Maria Pogliani, Vincenzo Cassibba, Daniele Mattei, Claudio Romani, Agostino Cortelezzi, Consuelo Corti, Anna Maria Scattolin, Orietta Spinelli, Manuela Tosi, Margherita Parolini, Filippo Marmont, Erika Borlenghi, Monica Fumagalli, Sergio Cortelazzo, Andrea Gallamini, Rosa Maria Marfisi, Elena Oldani, Alessandro Rambaldi

https://doi.org/10.3324/haematol.2014.123273

Resimmune, an anti-CD3ε recombinant immunotoxin, induces durable remissions in patients with cutaneous T-cell lymphoma (1310 Online Views)

Arthur E. Frankel, Jung H. Woo, Chul Ahn, Francine M. Foss, Madeleine Duvic, Paul H. Neville, David M. Neville

https://doi.org/10.3324/haematol.2015.123711

BCL6 – regulated by AhR/ARNT and wild-type MEF2B – drives expression of germinal center markers MYBL1 and LMO2 (1203 Online Views)

Jie Ding, Wilhelm G Dirks, Stefan Ehrentraut, Robert Geffers, Roderick AF MacLeod, Stefan Nagel, Claudia Pommerenke, Julia Romani, Michaela Scherr, Lea AI Vaas, Margarete Zaborski, Hans G Drexler, Hilmar Quentmeier

https://doi.org/10.3324/haematol.2014.120048

Outcome of and prognostic factors for relapse in children and adolescents with mature B-cell lymphoma and leukemia treated in three consecutive prospective “Lymphomes Malins B” protocols. A Société Française des Cancers de l’Enfant study (1324 Online Views)

Anne Jourdain, Anne Auperin, Véronique Minard-Colin, Nathalie Aladjidi, Josef Zsiros, Carole Coze, Virginie Gandemer, Yves Bertrand, Guy Leverger, Christophe Bergeron, Jean Michon, Catherine Patte, for the SFCE LNH Committee

https://doi.org/10.3324/haematol.2014.121434

A magnetic resonance imaging-based prognostic scoring system to predict outcome in transplant-eligible patients with multiple myeloma (942 Online Views)

Elias K. Mai, Thomas Hielscher, Jost K. Kloth, Maximilian Merz, Sofia Shah, Marc S. Raab, Michaela Hillengass, Barbara Wagner, Anna Jauch, Dirk Hose, Marc-André Weber, Stefan Delorme, Hartmut Goldschmidt, Jens Hillengass

https://doi.org/10.3324/haematol.2015.124115

Health-related quality-of-life in patients with newly diagnosed multiple myeloma in the FIRST trial: lenalidomide plus low-dose dexamethasone versus melphalan, prednisone, thalidomide (1753 Online Views)

Michel Delforge, Leonard Minuk, Jean-Claude Eisenmann, Bertrand Arnulf, Letizia Canepa, Alberto Fragasso, Serge Leyvraz, Christian Langer, Yousef Ezaydi, Dan T. Vogl, Pilar Giraldo-Castellano, Sung-Soo Yoon, Charles Zarnitsky, Martine Escoffre-Barbe, Bernard Lemieux, Kevin Song, Nizar Jacques Bahlis, Shien Guo, Mara Silva Monzini, Annette Ervin-Haynes, Vanessa Houck, Thierry Facon

https://doi.org/10.3324/haematol.2014.120121

Effectiveness and safety of lower dose prednisone for initial treatment of acute graft-versus-host disease: a randomized controlled trial (3144 Online Views)

Marco Mielcarek, Terrence Furlong, Barry E. Storer, Margaret L. Green, George B. McDonald, Paul A. Carpenter, Mary E.D. Flowers, Rainer Storb, Michael Boeckh, Paul J. Martin

https://doi.org/10.3324/haematol.2014.118471

Combined immunodeficiency with CD4 lymphopenia and sclerosing cholangitis caused by a novel loss-of-function mutation affecting IL21R (823 Online Views)

Baran Erman, Ivan Bilic, Tatjana Hirschmugl, Elisabeth Salzer, Deniz Çagdas, Saliha Esenboga, Zuhal Akcoren, Ozden Sanal, Ilhan Tezcan, Kaan Boztug

https://doi.org/10.3324/haematol.2014.120980

Regulatory T cells and progenitor B cells are independent prognostic predictors in lower risk myelodysplastic syndromes (740 Online Views)

Josephine D. Kahn, Martine E.D. Chamuleau, Theresa M. Westers, Peter M. Van de Ven, Linda van Dreunen, Margot van Spronsen, Gert J. Ossenkoppele, Arjan A. van de Loosdrecht

https://doi.org/10.3324/haematol.2014.116657

High-throughput mutational screening adds clinically important information in myelodysplastic syndromes and secondary or therapy-related acute myeloid leukemia (499 Online Views)

Mohsen Karimi, Christer Nilsson, Marios Dimitriou, Monika Jansson, Hans Matsson, Per Unneberg, Sören Lehmann, Juha Kere, Eva Hellström-Lindberg

https://doi.org/10.3324/haematol.2014.118034

Somatic calreticulin mutations in patients with Budd-Chiari syndrome and portal vein thrombosis (571 Online Views)

Elisabeth P.C. Plompen, Peter J.M. Valk, Isabel Chu, Sarwa Darwish Murad, Aurelie Plessier, Fanny Turon, Jonel Trebicka, Massimo Primignani, Juan Carlos Garcia-Pagán, Dominique C. Valla, Harry L.A. Janssen, Frank W.G. Leebeek

https://doi.org/10.3324/haematol.2014.120857

Fine tuning of surface CRLF2 expression and its associated signaling profile in childhood B-cell precursor acute lymphoblastic leukemia (1167 Online Views)

Cristina Bugarin, Jolanda Sarno, Chiara Palmi, Angela Maria Savino, Geertruy te Kronnie, Michael Dworzak, Angela Shumich, Barbara Buldini, Oscar Maglia, Simona Sala, Ilaria Bronzini, Jean-Pierre Bourquin, Ester Mejstrikova, Ondrej Hrusak, Drorit Luria, Giuseppe Basso, Shai Izraeli, Andrea Biondi, Giovanni Cazzaniga, Giuseppe Gaipa

https://doi.org/10.3324/haematol.2014.114447

High frequency of cryptic chromosomal rearrangements involving the LMO2 gene in T-cell acute lymphoblastic leukemia (581 Online Views)

Lili Wu, Yang Xu, Qian Wang, Changgeng Ruan, Hans G. Drexler, Depei Wu, Roderick A. F. MacLeod, Suning Chen

https://doi.org/10.3324/haematol.2014.120089

Low frequency mutations independently predict poor treatment-free survival in early stage chronic lymphocytic leukemia and monoclonal B-cell lymphocytosis (578 Online Views)

Nils Winkelmann, Matthew Rose-Zerilli, Jade Forster, Marina Parry, Anton Parker, Anne Gardiner, Zadie Davies, Andrew J. Steele, Helen Parker, Nicholas C.P. Cross, David G. Oscier, Jonathan C. Strefford

https://doi.org/10.3324/haematol.2014.120238

Conditional survival and excess mortality after high-dose therapy with autologous stem cell transplantation for adult refractory or relapsed Hodgkin lymphoma in Norway (1103 Online Views)

Knut B. Smeland, Cecilie E. Kiserud, Grete F. Lauritzsen, Unn-Merete Fagerli, Ragnhild S. Falk, Øystein Fluge, Alexander Fosså, Arne Kolstad, Jon H. Loge, Martin Maisenhölder, Stein Kvaløy, Harald Holte

https://doi.org/10.3324/haematol.2014.119214