April, 2013
No. 98 (4)

Editorials

Review Articles

Articles

Influence of molecular subgroups on outcome of acute myeloid leukemia with normal karyotype in 141 patients undergoing salvage allogeneic stem cell transplantation in primary induction failure or beyond first relapse

Tim Pfeiffer, Michael Schleuning, Jiri Mayer, Karl-Heinz Haude, Johanna Tischer, Stefanie Buchholz, Donald Bunjes, Gesine Bug, Ernst Holler, Ralf G. Meyer, Hildegard Greinix, Christof Scheid, Maximilian Christopeit, Susanne Schnittger, Jan Braess, Günter Schlimok, Karsten Spiekermann, Arnold Ganser, Hans-Jochem Kolb, Christoph Schmid

https://doi.org/10.3324/haematol.2012.070235

The combination of sirolimus plus tacrolimus improves outcome after reduced-intensity conditioning, unrelated donor hematopoietic stem cell transplantation compared with cyclosporine plus mycofenolate

Jose Antonio Perez-Simón, Rodrigo Martino, Rocío Parody, Mónica Cabrero, Lucía Lopez-Corral, David Valcarcel, Carmen Martinez, Carlos Solano, Lourdes Vazquez, Francisco J. Márquez-Malaver, Jordi Sierra, Dolores Caballero

https://doi.org/10.3324/haematol.2012.065599

Robust and cost effective expansion of human regulatory T cells highly functional in a xenograft model of graft-versus-host disease

Rikhia Chakraborty, Aruna Mahendravada, Serena K. Perna, Cliona M. Rooney, Helen E. Heslop, Juan F. Vera, Barbara Savoldo, Gianpietro Dotti

https://doi.org/10.3324/haematol.2012.076430

Differential effects of the type of iron chelator on the absolute number of hematopoietic peripheral progenitors in patients with β-thalassemia major

Gian Luca Forni, Marina Podestà, Marco Musso, Giovanna Piaggio, Khaled M. Musallam, Manuela Balocco, Sarah Pozzi, Alessandra Rosa, Francesco Frassoni

https://doi.org/10.3324/haematol.2012.076240

Molecular similarity between myelodysplastic form of chronic myelomonocytic leukemia and refractory anemia with ring sideroblasts

Véronique Gelsi-Boyer, Nathalie Cervera, François Bertucci, Mandy Brecqueville, Pascal Finetti, Anne Murati, Christine Arnoulet, Marie-Joelle Mozziconacci, Ken I. Mills, Nicholas C. P. Cross, Norbert Vey, Daniel Birnbaum

https://doi.org/10.3324/haematol.2012.071506

Treatment and outcomes for chronic myelomonocytic leukemia compared to myelodysplastic syndromes in older adults

Dan P. Zandberg, Ting-Ying Huang, Xuehua Ke, Maria R. Baer, Steven D. Gore, Sheila Weiss Smith, Amy J. Davidoff

https://doi.org/10.3324/haematol.2012.062547

Sequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemia

Daniel A. Pollyea, James Zehnder, Steve Coutre, Jason R. Gotlib, Leonel Gallegos, Omar Abdel-Wahab, Peter Greenberg, Bing Zhang, Michaela Liedtke, Caroline Berube, Ross Levine, Beverly S. Mitchell, Bruno C. Medeiros

https://doi.org/10.3324/haematol.2012.076414

Breakpoint-specific multiplex polymerase chain reaction allows the detection of IKZF1 intragenic deletions and minimal residual disease monitoring in B-cell precursor acute lymphoblastic leukemia

Aurélie Caye, Kheïra Beldjord, Kelly Mass-Malo, Séverine Drunat, Jean Soulier, Virginie Gandemer, André Baruchel, Yves Bertrand, Hélène Cavé, Emmanuelle Clappier

https://doi.org/10.3324/haematol.2012.073965

MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation

Martina Pigazzi, Elena Manara, Silvia Bresolin, Claudia Tregnago, Alessandra Beghin, Emma Baron, Emanuela Giarin, Er-Chieh Cho, Riccardo Masetti, Dinesh S. Rao, Kathleen M. Sakamoto, Giuseppe Basso

https://doi.org/10.3324/haematol.2012.070664

Myeloablative chemotherapy for chemo-sensitive recurrent follicular lymphoma: potential benefit in second relapse

Silvia Montoto, Janet Matthews, Paul Greaves, Debra Lillington, Deborah Anderson, John G. Gribben, T. Andrew Lister

https://doi.org/10.3324/haematol.2012.069583

Association between B-cell receptor responsiveness and disease progression in B-cell chronic lymphocytic leukemia: results from single cell network profiling studies

Alessandra Cesano, Omar Perbellini, Erik Evensen, Charles C. Chu, Federica Cioffi, Jason Ptacek, Rajendra N. Damle, Roberto Chignola, James Cordeiro, Xiao-jie Yan, Rachael E. Hawtin, Ilaria Nichele, Jodi R. Ware, Chiara Cavallini, Ornella Lovato, Roberta Zanotti, Kanti R. Rai, Nicholas Chiorazzi, Giovanni Pizzolo, Maria T. Scupoli

https://doi.org/10.3324/haematol.2012.071910

Constant activation of the RAF-MEK-ERK pathway as a diagnostic and therapeutic target in hairy cell leukemia

Enrico Tiacci, Gianluca Schiavoni, Maria Paola Martelli, Emanuela Boveri, Roberta Pacini, Alessia Tabarrini, Silvia Zibellini, Alessia Santi, Valentina Pettirossi, Elisabetta Fortini, Stefano Ascani, Luca Arcaini, Giorgio Inghirami, Marco Paulli, Brunangelo Falini

https://doi.org/10.3324/haematol.2012.078071

Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia

Florence Nguyen-Khac, Jerome Lambert, Elise Chapiro, Aurore Grelier, Sarah Mould, Carole Barin, Agnes Daudignon, Nathalie Gachard, Stéphanie Struski, Catherine Henry, Dominique Penther, Hossein Mossafa, Joris Andrieux, Virginie Eclache, Chrystèle Bilhou-Nabera, Isabelle Luquet, Christine Terre, Laurence Baranger, Francine Mugneret, Jean Chiesa, Marie-Joelle Mozziconacci, Evelyne Callet-Bauchu, Lauren Veronese, Hélène Blons, Roger Owen, Julie Lejeune, Sylvie Chevret, Hélène Merle-Beral, Véronique Leblond

https://doi.org/10.3324/haematol.2012.070458

Letters to the Editor

In utero and early postnatal presentation of autoimmune lymphoproliferative syndrome in a family with a novel FAS mutation

Jordan R. Hansford, Manika Pal, Nicola Poplawski, Eric Haan, Bernadette Boog, Antonio Ferrante, Joie Davis, Julie E. Niemela, V. Koneti Rao, Ram Suppiah

https://doi.org/10.3324/haematol.2012.070524

HA14-1, but not the BH3 mimetic ABT-737, causes Ca2+ dysregulation in platelets and human cell lines

Haidar Akl, Ilse Vandecaetsbeek, Giovanni Monaco, Alexandre Kauskot, Tomas Luyten, Kirsten Welkenhuyzen, Marc Hoylaerts, Humbert De Smedt, Jan B. Parys, Geert Bultynck

https://doi.org/10.3324/haematol.2012.080598

Acute myeloid leukemia with translocation t(3;5): new molecular insights

Florent Dumézy, Aline Renneville, Caroline Mayeur-Rousse, Olivier Nibourel, Elise Labis, Claude Preudhomme

https://doi.org/10.3324/haematol.2012.082149

Genomic breakpoints and clinical features of MLL-TET1 rearrangement in acute leukemias

Sang-Guk Lee, Sun Young Cho, Min Jin Kim, Seung Hwan Oh, Eun Hae Cho, Sanggyu Lee, Eun Jung Baek, Jung Hye Choi, Stefan K. Bohlander, Laurence Lode, Steven Richebourg, Hwi-Joong Yoon, Rolf Marschalek, Claus Meyer, Tae Sung Park

https://doi.org/10.3324/haematol.2012.076323

Original Articles and Brief Reports

Involvement of TGFβ1 in autocrine regulation of proplatelet formation in healthy subjects and patients with primary myelofibrosis

Stefania Badalucco, Christian Andrea Di Buduo, Rita Campanelli, Isabella Pallotta, Paolo Catarsi, Vittorio Rosti, David L. Kaplan, Giovanni Barosi, Margherita Massa, Alessandra Balduini

https://doi.org/10.3324/haematol.2012.076752

Disorders of Coagulation

Prophylaxis in congenital factor VII deficiency: indications, efficacy and safety. Results from the Seven Treatment Evaluation Registry (STER)

Mariasanta Napolitano, Muriel Giansily-Blaizot, Alberto Dolce, Jean F. Schved, Guenter Auerswald, Jørgen Ingerslev, Jens Bjerre, Carmen Altisent, Pimlak Charoenkwan, Lisa Michaels, Ampaiwan Chuansumrit, Giovanni Di Minno, Ümran Caliskan, Guglielmo Mariani

https://doi.org/10.3324/haematol.2012.074039

Predicting deep venous thrombosis in pregnancy: external validation of the LEFT clinical prediction rule

Marc Righini, Christelle Jobic, Françoise Boehlen, Jean Broussaud, François Becker, Morgan Jaffrelot, Marc Blondon, Bruno Guias, Grégoire Le Gal, the EDVIGE study group

https://doi.org/10.3324/haematol.2012.072009

The phenotype of polycythemia due to Croatian homozygous VHL (571C>G:H191D) mutation is different from that of Chuvash polycythemia (VHL 598C>T:R200W)

Nikica Ljubas Tomasic, Lucie Piterkova, Chad Huff, Ernest Bilic, Donghoon Yoon, Galina Y. Miasnikova, Adelina I. Sergueeva, Xiaomei Niu, Sergei Nekhai, Victor Gordeuk, Josef T. Prchal

https://doi.org/10.3324/haematol.2012.070508

Everolimus in combination with rituximab induces complete responses in heavily pretreated diffuse large B-cell lymphoma

Jeffrey A. Barnes, Eric Jacobsen, Yang Feng, Arnold Freedman, Ephraim P. Hochberg, Ann S. LaCasce, Philippe Armand, Robin Joyce, Aliyah R. Sohani, Scott J. Rodig, Donna Neuberg, David C. Fisher, Jeremy S. Abramson

https://doi.org/10.3324/haematol.2012.075184

Restoration of microRNA-214 expression reduces growth of myeloma cells through positive regulation of P53 and inhibition of DNA replication

Irena Misiewicz-Krzeminska, María E. Sarasquete, Dalia Quwaider, Patryk Krzeminski, Fany V. Ticona, Teresa Paíno, Manuel Delgado, Andreia Aires, Enrique M. Ocio, Ramón García-Sanz, Jesús F. San Miguel, Norma C. Gutiérrez

https://doi.org/10.3324/haematol.2012.070011