March, 2013
No. 98 (3)

Editorials

Articles

B-lymphopoiesis is stopped by mobilizing doses of G-CSF and is rescued by overexpression of the anti-apoptotic protein Bcl2

Ingrid G. Winkler, Linda J. Bendall, Catherine E. Forristal, Falak Helwani, Bianca Nowlan, Valerie Barbier, Yi Shen, Adam Cisterne, Lisa M. Sedger, Jean-Pierre Levesque

https://doi.org/10.3324/haematol.2012.069260

Mutations in the telomere capping complex in bone marrow failure and related syndromes

Amanda J. Walne, Tanya Bhagat, Michael Kirwan, Cyril Gitiaux, Isabelle Desguerre, Norma Leonard, Elena Nogales, Tom Vulliamy, Inderjeet S. Dokal

https://doi.org/10.3324/haematol.2012.071068

Ongoing graft-versus-host disease is a risk factor for azoospermia after allogeneic hematopoietic stem cell transplantation: a survey of the Late Effects Working Party of the European Group for Blood and Marrow Transplantation

Alicia Rovó, Mahmoud Aljurf, Sandra Chiodi, Simonetta Spinelli, Nina Salooja, Gülsan Sucak, Ann Hunter, Tan Swee Kim, Gérard Socié, Maria Teresa van Lint, Jakob R. Passweg, Mutlu Arat, Manuela Badoglio, André Tichelli

https://doi.org/10.3324/haematol.2012.071944

Donor lymphocyte count and thymic activity predict lymphocyte recovery and outcomes after matched-sibling hematopoietic stem cell transplant

Zachariah McIver, Jan Joseph Melenhorst, Colin Wu, Andrew Grim, Sawa Ito, Irene Cho, Nancy Hensel, Minoo Battiwalla, Austin John Barrett

https://doi.org/10.3324/haematol.2012.072991

Multicenter phase II study of plitidepsin in patients with relapsed/refractory non-Hodgkin’s lymphoma

Vincent Ribrag, Dolores Caballero, Christophe Fermé, Emanuele Zucca, Reyes Arranz, Javier Briones, Christian Gisselbrecht, Gilles Salles, Alessandro M. Gianni, Henry Gomez, Carmen Kahatt, Claudia Corrado, Sergio Szyldergemajn, Sonia Extremera, Bernardo de Miguel, Martin Cullell-Young, Franco Cavalli

https://doi.org/10.3324/haematol.2012.069757

Phase II study of central nervous system (CNS)-directed chemotherapy including high-dose chemotherapy with autologous stem cell transplantation for CNS relapse of aggressive lymphomas

Agnieszka Korfel, Thomas Elter, Eckhard Thiel, Matthias Hänel, Robert Möhle, Roland Schroers, Marcel Reiser, Martin Dreyling, Jan Eucker, Christian Scholz, Bernd Metzner, Alexander Röth, Josef Birkmann, Uwe Schlegel, Peter Martus, Gerard Illerhaus, Lars Fischer

https://doi.org/10.3324/haematol.2012.077917

Identification of molecular and functional patterns of p53 alterations in chronic lymphocytic leukemia patients in different phases of the disease

Marilisa Marinelli, Nadia Peragine, Valeria Di Maio, Sabina Chiaretti, Maria Stefania De Propris, Sara Raponi, Simona Tavolaro, Francesca Romana Mauro, Ilaria Del Giudice, Anna Guarini, Robin Foà

https://doi.org/10.3324/haematol.2012.069906

Diagnosis of autoimmune lymphoproliferative syndrome caused by FAS deficiency in adults

Olivier Lambotte, Bénédicte Neven, Lionel Galicier, Aude Magerus-Chatinet, Nicolas Schleinitz, Olivier Hermine, Isabelle Meyts, Capucine Picard, Bertrand Godeau, Alain Fischer, Frédéric Rieux-Laucat

https://doi.org/10.3324/haematol.2012.067488

Pulmonary hypertension in POEMS syndrome

Jian Li, Zhuang Tian, Hao-Yi Zheng, Wei Zhang, Ming-Hui Duan, Yong-Tai Liu, Xin-Xin Cao, Dao-Bin Zhou

https://doi.org/10.3324/haematol.2012.073031

Outcome of 82 chronic myeloid leukemia patients treated with nilotinib or dasatinib after failure of two prior tyrosine kinase inhibitors

Antonella Russo Rossi, Massimo Breccia, Elisabetta Abruzzese, Fausto Castagnetti, Luigiana Luciano, Antonella Gozzini, Mario Annunziata, Bruno Martino, Fabio Stagno, Francesco Cavazzini, Mario Tiribelli, Giuseppe Visani, Patrizia Pregno, Pellegrino Musto, Carmen Fava, Nicola Sgherza, Francesco Albano, Gianantonio Rosti, Giuliana Alimena, Giorgina Specchia

https://doi.org/10.3324/haematol.2012.064337

Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements

Andrew Chase, Catherine Bryant, Joannah Score, Claudia Haferlach, Vera Grossmann, Juliana Schwaab, Wolf-Karsten Hofmann, Andreas Reiter, Nicholas C.P. Cross

https://doi.org/10.3324/haematol.2012.067959

Correlation of clinical response and response duration with miR-145 induction by lenalidomide in CD34+ cells from patients with del(5q) myelodysplastic syndrome

Christopher P. Venner, Joanna Wegrzyn Woltosz, Thomas J. Nevill, H. Joachim Deeg, Gisela Caceres, Uwe Platzbecker, Bart L. Scott, Lubomir Sokol, Sandy Sung, Alan F. List, Aly Karsan

https://doi.org/10.3324/haematol.2012.066068

Transcriptional regulation of miR-10a/b by TWIST-1 in myelodysplastic syndromes

Xiang Li, Feng Xu, ChunKang Chang, John Byon, Thalia Papayannopoulou, H. Joachim Deeg, A. Mario Marcondes

https://doi.org/10.3324/haematol.2012.071753

Inappropriately low hepcidin levels in patients with myelodysplastic syndrome carrying a somatic mutation of SF3B1

Ilaria Ambaglio, Luca Malcovati, Elli Papaemmanuil, Coby M. Laarakkers, Matteo G. Della Porta, Anna Gallì, Matteo C. Da Vià, Elisa Bono, Marta Ubezio, Erica Travaglino, Riccardo Albertini, Peter J. Campbell, Dorine W. Swinkels, Mario Cazzola

https://doi.org/10.3324/haematol.2012.077446

PML-RARα co-operates with Sox4 in acute myeloid leukemia development in mice

Nader Omidvar, Mei Lin Maunakea, Letetia Jones, Sabina Sevcikova, Bin Yin, Karen L. Himmel, Thelma R. Tennant, Michelle M. Le Beau, David A. Largaespada, Scott C. Kogan

https://doi.org/10.3324/haematol.2011.057067

IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol

Petra Dörge, Barbara Meissner, Martin Zimmermann, Anja Möricke, André Schrauder, Jean-Pierre Bouquin, Denis Schewe, Jochen Harbott, Andrea Teigler-Schlegel, Richard Ratei, Wolf-Dieter Ludwig, Rolf Koehler, Claus R. Bartram, Martin Schrappe, Martin Stanulla, Gunnar Cario

https://doi.org/10.3324/haematol.2011.056135

A phase II trial of cyclophosphamide, lenalidomide and dexamethasone in previously treated patients with AL amyloidosis

Giovanni Palladini, Paola Russo, Paolo Milani, Andrea Foli, Francesca Lavatelli, Mario Nuvolone, Stefano Perlini, Giampaolo Merlini

https://doi.org/10.3324/haematol.2012.073593

Analysis of incidence, risk factors and clinical outcome of thromboembolic and bleeding events in 431 allogeneic hematopoietic stem cell transplantation recipients

Jorge Labrador, Lucia Lopez-Anglada, Estefania Perez-Lopez, Francisco S. Lozano, Lucia Lopez-Corral, Fermin M. Sanchez-Guijo, Lourdes Vazquez, Jose Angel Perez Rivera, Francisco Martin-Herrero, Mercedes Sanchez-Barba, Carmen Guerrero, Maria Consuelo del Cañizo, Maria Dolores Caballero, Jesus Fernando San Miguel, Ignacio Alberca, Jose Ramon Gonzalez-Porras

https://doi.org/10.3324/haematol.2012.069559

The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice

Guillem Casanovas, Maja Vujić Spasić, Carla Casu, Stefano Rivella, Jens Strelau, Klaus Unsicker, Martina U. Muckenthaler

https://doi.org/10.3324/haematol.2012.069807

Plasma hepcidin levels and anemia in old age. The Leiden 85-Plus Study

Wendy P.J. den Elzen, Anton J.M. de Craen, Erwin T. Wiegerinck, Rudi G.J. Westendorp, Dorine W. Swinkels, Jacobijn Gussekloo

https://doi.org/10.3324/haematol.2012.068825

Reduced sensitivity of the ferroportin Q248H mutant to physiological concentrations of hepcidin

Sergei Nekhai, Min Xu, Altreisha Foster, Ishmael Kasvosve, Sharmin Diaz, Roberto F. Machado, Oswaldo L. Castro, Gregory J. Kato, James G. Taylor, Victor R. Gordeuk

https://doi.org/10.3324/haematol.2012.066530

The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe

Mehdi Nouraie, Janet S. Lee, Yingze Zhang, Tamir Kanias, Xuejun Zhao, Zeyu Xiong, Timothy B. Oriss, Qilu Zeng, Gregory J. Kato, J. Simon R. Gibbs, Mariana E. Hildesheim, Vandana Sachdev, Robyn J. Barst, Roberto F. Machado, Kathryn L. Hassell, Jane A. Little, Dean E. Schraufnagel, Lakshmanan Krishnamurti, Enrico Novelli, Reda E. Girgis, Claudia R. Morris, Erika Berman Rosenzweig, David B. Badesch, Sophie Lanzkron, Oswaldo L. Castro, Jonathan C. Goldsmith, Victor R. Gordeuk, Mark T. Gladwin

https://doi.org/10.3324/haematol.2012.068965

Combined immunodeficiency with life-threatening EBV-associated lymphoproliferative disorder in patients lacking functional CD27

Elisabeth Salzer, Svenja Daschkey, Sharon Choo, Michael Gombert, Elisangela Santos-Valente, Sebastian Ginzel, Martina Schwendinger, Oskar A. Haas, Gerhard Fritsch, Winfried F. Pickl, Elisabeth Förster-Waldl, Arndt Borkhardt, Kaan Boztug, Kirsten Bienemann, Markus G. Seidel

https://doi.org/10.3324/haematol.2012.068791

A high level of fatigue among long-term survivors of non-Hodgkin’s lymphoma: results from the longitudinal population-based PROFILES registry in the south of the Netherlands

Simone Oerlemans, Floortje Mols, Djamila E. Issa, J. H. F. M. Pruijt, Wim G. Peters, Marnix Lybeert, Wobbe Zijlstra, Jan Willem W. Coebergh, Lonneke V. van de Poll-Franse

https://doi.org/10.3324/haematol.2012.064907

Letters to the Editor

Bone metabolism, growth rate and pubertal development in children with chronic myeloid leukemia treated with imatinib during puberty

Fiorina Giona, Stefania Mariani, Lucio Gnessi, Maria Luisa Moleti, Massimiliano Rea, Annalisa De Vellis, Deborah Marzella, Anna Maria Testi, Robin Foà

https://doi.org/10.3324/haematol.2012.067447