Vol. 98 No. 2 (2013): February, 2013

JAK inhibitors: beyond spleen and symptoms? (443 Online Views)

Francisco Cervantes, Ruben Mesa, Claire Harrison

https://doi.org/10.3324/haematol.2012.083543

Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells (1740 Online Views)

Bahar Mirshekar-Syahkal, Esther Haak, Gillian M. Kimber, Kevin van Leusden, Kirsty Harvey, John O'Rourke, Jorge Laborda, Steven R. Bauer, Marella F. T. R. de Bruijn, Anne C. Ferguson-Smith, Elaine Dzierzak, Katrin Ottersbach

https://doi.org/10.3324/haematol.2012.070789

Plerixafor and granulocyte colony-stimulating factor for first-line steady-state autologous peripheral blood stem cell mobilization in lymphoma and multiple myeloma: results of the prospective PREDICT trial (1517 Online Views)

Nigel Russell, Kenny Douglas, Anthony D. Ho, Mohamad Mohty, Kristina Carlson, G.J. Ossenkoppele, Giuseppe Milone, Macarena Ortiz Pareja, Daniel Shaheen, Arnold Willemsen, Nicky Whitaker, Christian Chabannon

https://doi.org/10.3324/haematol.2012.071456

Autologous blood cell transplantation versus HLA-identical sibling transplantation for acute myeloid leukemia in first complete remission: a registry study from the Center for International Blood and Marrow Transplantation Research (822 Online Views)

Armand Keating, Gisela DaSilva, Waleska S. Pérez, Vikas Gupta, Corey S. Cutler, Karen K. Ballen, Mitchell S. Cairo, Bruce M. Camitta, Richard E. Champlin, James L. Gajewski, Hillard M. Lazarus, Michael Lill, David I. Marks, Chadi Nabhan, Gary J. Schiller, Gerald Socie, Jeffrey Szer, Martin S. Tallman, Daniel J. Weisdorf

https://doi.org/10.3324/haematol.2012.062059

Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy (1794 Online Views)

Sabrina Angelini, Simona Soverini, Gloria Ravegnini, Matt Barnett, Eleonora Turrini, Mark Thornquist, Fabrizio Pane, Timothy P. Hughes, Deborah L. White, Jerald Radich, Dong Wook Kim, Giuseppe Saglio, Daniela Cilloni, Ilaria Iacobucci, Giovanni Perini, Richard Woodman, Giorgio Cantelli-Forti, Michele Baccarani, Patrizia Hrelia, Giovanni Martinelli

https://doi.org/10.3324/haematol.2012.066480

Serial assessment of suspected myelodysplastic syndromes: significance of flow cytometric findings validated by cytomorphology, cytogenetics, and molecular genetics (870 Online Views)

Wolfgang Kern, Claudia Haferlach, Susanne Schnittger, Tamara Alpermann, Torsten Haferlach

https://doi.org/10.3324/haematol.2012.066787

Parameters detected by geriatric and quality of life assessment in 195 older patients with myelodysplastic syndromes and acute myeloid leukemia are highly predictive for outcome (1684 Online Views)

Barbara Deschler, Gabriele Ihorst, Uwe Platzbecker, Ulrich Germing, Eva März, Marcelo de Figuerido, Kurt Fritzsche, Peter Haas, Helmut R. Salih, Aristoteles Giagounidis, Dominik Selleslag, Boris Labar, Theo de Witte, Pierre Wijermans, Michael Lübbert

https://doi.org/10.3324/haematol.2012.067892

Phase 1 study of an anti-CD33 immunotoxin, humanized monoclonal antibody M195 conjugated to recombinant gelonin (HUM-195/rGEL), in patients with advanced myeloid malignancies (1537 Online Views)

Gautam Borthakur, Michael G. Rosenblum, Moshe Talpaz, Naval Daver, Farhad Ravandi, Stefan Faderl, Emil J. Freireich, Tapan Kadia, Guillermo Garcia-Manero, Hagop Kantarjian, Jorge E. Cortes

https://doi.org/10.3324/haematol.2012.071092

Recent trends in survival of adult patients with acute leukemia: overall improvements, but persistent and partly increasing disparity in survival of patients from minority groups (1798 Online Views)

Dianne Pulte, Maria Theresa Redaniel, Lina Jansen, Hermann Brenner, Mona Jeffreys

https://doi.org/10.3324/haematol.2012.063602

Survival of European patients diagnosed with myeloid malignancies: a HAEMACARE study (1826 Online Views)

Marc Maynadié, Roberta De Angelis, Rafael Marcos-Gragera, Otto Visser, Claudia Allemani, Carmen Tereanu, Riccardo Capocaccia, Adriano Giacomin, Jean-Michel Lutz, Carmen Martos, Risto Sankila, Tom Børge Johannesen, Arianna Simonetti, Milena Sant, the HAEMACARE Working Group

https://doi.org/10.3324/haematol.2012.064014

Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: an Italian multicenter study (3654 Online Views)

Livio Pagano, Caterina Giovanna Valentini, Alessandro Pulsoni, Simona Fisogni, Paola Carluccio, Francesco Mannelli, Monia Lunghi, Gianmatteo Pica, Francesco Onida, Chiara Cattaneo, Pier Paolo Piccaluga, Eros Di Bona, Elisabetta Todisco, Pellegrino Musto, Antonio Spadea, Alfonso D'Arco, Stefano Pileri, Giuseppe Leone, Sergio Amadori, Fabio Facchetti

https://doi.org/10.3324/haematol.2012.072645

Histone acetylation and DNA demethylation of T cells result in an anaplastic large cell lymphoma-like phenotype (963 Online Views)

Maria Joosten, Volkhard Seitz, Karin Zimmermann, Anke Sommerfeld, Erika Berg, Dido Lenze, Ulf Leser, Harald Stein, Michael Hummel

https://doi.org/10.3324/haematol.2011.054619

Patients with diffuse large B-cell lymphoma of germinal center origin with BCL2 translocations have poor outcome, irrespective of MYC status: a report from an International DLBCL rituximab-CHOP Consortium Program Study (4740 Online Views)

Carlo Visco, Alexander Tzankov, Zijun Y. Xu-Monette, Roberto N. Miranda, Yu Chuan Tai, Yan Li, Wei-min Liu, Emanuele S. G. d'Amore, Yong Li, Santiago Montes-Moreno, Karen Dybkær, April Chiu, Attilio Orazi, Youli Zu, Govind Bhagat, Huan-You Wang, Cherie H. Dunphy, Eric D. His, X. Frank Zhao, William WL. Choi, Xiaoying Zhao, J. Han van Krieken, Qin Huang, Weiyun Ai, Stacey O'Neill, Maurilio Ponzoni, Andres JM. Ferreri, Brad S. Kahl, Jane N. Winter, Ronald S. Go, Stephan Dirnhofer, Miguel A. Piris, Michael B. Møller, Lin Wu, L. Jeffrey Medeiros, Ken H. Young

https://doi.org/10.3324/haematol.2012.066209

Rituximab plus subcutaneous cladribine in patients with extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue: a phase II study by the Arbeitsgemeinschaft Medikamentöse Tumortherapie (618 Online Views)

Marlene Troch, Barbara Kiesewetter, Wolfgang Willenbacher, Ella Willenbacher, Armin Zebisch, Werner Linkesch, Michael Fridrik, Leonhard Müllauer, Richard Greil, Markus Raderer

https://doi.org/10.3324/haematol.2012.072587

TCL1A and ATM are co-expressed in chronic lymphocytic leukemia cells without deletion of 11q (834 Online Views)

Angela Garding, Nupur Bhattacharya, Sarah Haebe, Frederike Müller, Dieter Weichenhan, Irina Idler, Katja Ickstadt, Stephan Stilgenbauer, Daniel Mertens

https://doi.org/10.3324/haematol.2012.070623

CLLU1 expression has prognostic value in chronic lymphocytic leukemia after first-line therapy in younger patients and in those with mutated IGHV genes (708 Online Views)

David Gonzalez, Monica Else, Dorte Wren, Monica Usai, Anne Mette Buhl, Anton Parker, David Oscier, Gareth Morgan, Daniel Catovsky

https://doi.org/10.3324/haematol.2012.070201

Cytogenetic profiles in multiple myeloma and monoclonal gammopathy of undetermined significance: a study in highly purified aberrant plasma cells (2043 Online Views)

Martin Schmidt-Hieber, María Laura Gutiérrez, Martin Pérez-Andrés, Bruno Paiva, Ana Rasillo, Maria Dolores Tabernero, José Maria Sayagués, Antonio Lopez, Paloma Bárcena, María Luz Sanchez, Norma C. Gutiérrez, Jesus F. San Miguel, Alberto Orfao

https://doi.org/10.3324/haematol.2011.060632

Platelet factor 4 induces cell apoptosis by inhibition of STAT3 via up-regulation of SOCS3 expression in multiple myeloma (1225 Online Views)

Pei Liang, Suk Hang Cheng, Chi Keung Cheng, Kin Mang Lau, Shek Ying Lin, Eudora Y.D. Chow, Natalie P.H. Chan, Rosalina K.L. Ip, Raymond S.M. Wong, Margaret H. L. Ng

https://doi.org/10.3324/haematol.2012.065607

A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum (660 Online Views)

Wenjie Chen, Chia Chi Sun, Shanzhuo Chen, Delphine Meynard, Jodie L. Babitt, Herbert Y. Lin

https://doi.org/10.3324/haematol.2012.070136

Estimation of the difference in HbF expression due to loss of the 5' δ-globin BCL11A binding region (1187 Online Views)

Elyes Slim Ghedira, Laure Lecerf, Emmanuelle Faubert, Bruno Costes, Kamran Moradkhani, Dora Bachir, Frédéric Galactéros, Serge Pissard

https://doi.org/10.3324/haematol.2012.061994

Finding the origin of pulmonary emboli with a total-body magnetic resonance direct thrombus imaging technique (2397 Online Views)

Kirsten van Langevelde, Alexandr Šrámek, Patrice W.J. Vincken, Jan-Kees van Rooden, Frits R. Rosendaal, Suzanne C. Cannegieter

https://doi.org/10.3324/haematol.2012.069195

MHC class II/ESO tetramer-based generation of in vitro primed anti-tumor T-helper lines for adoptive cell therapy of cancer (878 Online Views)

Caroline Poli, Caroline Raffin, Danijel Dojcinovic, Immanuel Luescher, Maha Ayyoub, Danila Valmori

https://doi.org/10.3324/haematol.2012.071712

Extramedullary relapse of acute myeloid leukemia following allogeneic hematopoietic stem cell transplantation: incidence, risk factors and outcomes (1467 Online Views)

Andrew C. Harris, Carrie L. Kitko, Daniel R. Couriel, Thomas M. Braun, Sung W. Choi, John Magenau, Shin Mineishi, Attaphol Pawarode, Gregory Yanik, John E. Levine

https://doi.org/10.3324/haematol.2012.073189

Impact of FLT3 ITD/NPM1 mutation status in adult patients with acute myelocytic leukemia autografted in first remission (474 Online Views)

Norbert-Claude Gorin, Myriam Labopin, Giovanna Meloni, Arnaud Pigneux, Jordi Esteve, Mohty Mohamad

https://doi.org/10.3324/haematol.2012.064436

High frequencies of SF3B1 and JAK2 mutations in refractory anemia with ring sideroblasts associated with marked thrombocytosis strengthen the assignment to the category of myelodysplastic/myeloproliferative neoplasms (803 Online Views)

Sabine Jeromin, Torsten Haferlach, Vera Grossmann, Tamara Alpermann, Andreas Kowarsch, Claudia Haferlach, Wolfgang Kern, Susanne Schnittger

https://doi.org/10.3324/haematol.2012.072538

Outcome of patients with low-risk myelodysplasia after azacitidine treatment failure (551 Online Views)

Thomas Prébet, Sylvain Thepot, Steven D. Gore, François Dreyfus, Pierre Fenaux, Norbert Vey

https://doi.org/10.3324/haematol.2012.071050

Low-dose vemurafenib induces complete remission in a case of hairy-cell leukemia with a V600E mutation (652 Online Views)

Frederic Peyrade, Daniel Re, Clemence Ginet, Lauris Gastaud, Maryline Allegra, Robert Ballotti, Antoine Thyss, Thorsten Zenz, Patrick Auberger, Guillaume Robert

https://doi.org/10.3324/haematol.2012.082404