March, 2012
No. 97 (3)

Editorials

Articles

Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity (804 Online Views)

Shabnam H. Thathia, Stuart Ferguson, Hannah E. Gautrey, Sanne D. van Otterdijk, Michela Hili, Vikki Rand, Anthony V. Moorman, Stefan Meyer, Robert Brown, Gordon Strathdee

https://doi.org/10.3324/haematol.2011.049593

Functional analysis of the NUP98-CCDC28A fusion protein (808 Online Views)

Arnaud Petit, Christine Ragu, Gwendoline Soler, Chris Ottolenghi, Caroline Schluth, Isabelle Radford-Weiss, Sylvie Schneider-Maunoury, Isabelle Callebaut, Nicole Dastugue, Harry A. Drabkin, Olivier A. Bernard, Serge Romana, Virginie Penard-Lacronique

https://doi.org/10.3324/haematol.2011.047969

Acquired mutations in ASXL1 in acute myeloid leukemia: prevalence and prognostic value (1755 Online Views)

Marta Pratcorona, Saman Abbas, Mathijs A. Sanders, Jasper E. Koenders, François G. Kavelaars, Claudia A.J. Erpelinck-Verschueren, Annelieke Zeilemakers, Bob Löwenberg, Peter J.M. Valk

https://doi.org/10.3324/haematol.2011.051532

A multicenter phase II trial of decitabine as first-line treatment for older patients with acute myeloid leukemia judged unfit for induction chemotherapy (2871 Online Views)

Michael Lübbert, Björn H. Rüter, Rainer Claus, Claudia Schmoor, Mathias Schmid, Ulrich Germing, Andrea Kuendgen, Volker Rethwisch, Arnold Ganser, Uwe Platzbecker, Oliver Galm, Wolfram Brugger, Gerhard Heil, Björn Hackanson, Barbara Deschler, Konstanze Döhner, Anne Hagemeijer, Pierre W. Wijermans, Hartmut Döhner

https://doi.org/10.3324/haematol.2011.048231

Low platelet counts after induction therapy for childhood acute lymphoblastic leukemia are strongly associated with poor early response to treatment as measured by minimal residual disease and are prognostic for treatment outcome (1092 Online Views)

Lutz Zeidler, Martin Zimmermann, Anja Möricke, Barbara Meissner, Dorothee Bartels, Christoph Tschan, André Schrauder, Gunnar Cario, Lilia Goudeva, Sarah Jäger, Richard Ratei, Wolf-Dieter Ludwig, Andrea Teigler-Schlegel, Julia Skokowa, Rolf Koehler, Claus R. Bartram, Hansjörg Riehm, Martin Schrappe, Karl Welte, Martin Stanulla

https://doi.org/10.3324/haematol.2011.045229

NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL (2169 Online Views)

Ilaria Del Giudice, Davide Rossi, Sabina Chiaretti, Marilisa Marinelli, Simona Tavolaro, Sara Gabrielli, Luca Laurenti, Roberto Marasca, Silvia Rasi, Marco Fangazio, Anna Guarini, Gianluca Gaidano, Robin Foà

https://doi.org/10.3324/haematol.2011.060129

Cyclophosphamide, thalidomide, and dexamethasone as induction therapy for newly diagnosed multiple myeloma patients destined for autologous stem-cell transplantation: MRC Myeloma IX randomized trial results (2101 Online Views)

Gareth J. Morgan, Faith E. Davies, Walter M. Gregory, Sue E. Bell, Alexander J. Szubert, Nuria Navarro Coy, Gordon Cook, Sylvia Feyler, Peter R.E. Johnson, Claudius Rudin, Mark T. Drayson, Roger G. Owen, Fiona M. Ross, Nigel H. Russell, Graham H. Jackson, J. Anthony Child

https://doi.org/10.3324/haematol.2011.043372

Overlap subtype of chronic graft-versus-host disease is associated with an adverse prognosis, functional impairment, and inferior patient-reported outcomes: a Chronic Graft-versus-Host Disease Consortium study (900 Online Views)

Joseph Pidala, Georgia Vogelsang, Paul Martin, Xiaoyu Chai, Barry Storer, Steven Pavletic, Daniel J. Weisdorf, Madan Jagasia, Corey Cutler, Jeanne Palmer, David Jacobsohn, Sally Arai, Stephanie J. Lee

https://doi.org/10.3324/haematol.2011.055186

Universal antifungal therapy is not needed in persistent febrile neutropenia: a tailored diagnostic and therapeutic approach (881 Online Views)

Manuela Aguilar-Guisado, Almudena Martín-Peña, Ildefonso Espigado, Maite Ruiz Pérez de Pipaon, José Falantes, Fátima de la Cruz, José M. Cisneros

https://doi.org/10.3324/haematol.2011.049999

Letters to the Editor

Iron deficiency does not compromise the diagnosis of high HbA2 β thalassemia trait (1613 Online Views)

Cristina Passarello, Antonino Giambona, Monica Cannata, Margherita Vinciguerra, Disma Renda, Aurelio Maggio

https://doi.org/10.3324/haematol.2011.052357

Hematology News

Online Only Articles

Original Articles and Brief Reports

Thrombolytic therapy is effective in paroxysmal nocturnal hemoglobinuria: a series of nine patients and a review of the literature (1095 Online Views)

David J. Araten, Rosario Notaro, Howard T Thaler, Nancy Kernan, Farid Boulad, Hugo Castro-Malaspina, Trudy Small, Andromachi Scaradavou, Heather Magnan, Susan Prockop, Sara Chaffee, Jason Gonsky, Raymond Thertulien, Roberto Tarquini, Lucio Luzzatto

https://doi.org/10.3324/haematol.2011.049767

A risk of essential thrombocythemia in carriers of constitutional CHEK2 gene mutations (1123 Online Views)

Hanna Janiszewska, Aneta Bąk, Maria Pilarska, Marta Heise, Anna Junkiert-Czarnecka, Małgorzata Kuliszkiewicz-Janus, Małgorzata Całbecka, Bożena JaŸwiec, Dariusz Wołowiec, Kazimierz Kuliczkowski, Olga Haus

https://doi.org/10.3324/haematol.2011.049494

Plasma thymus and activation-regulated chemokine as an early response marker in classical Hodgkin’s lymphoma (698 Online Views)

Wouter J. Plattel, Anke van den Berg, Lydia Visser, Anne-Marijn van der Graaf, Jan Pruim, Hans Vos, Bouke Hepkema, Arjan Diepstra, Gustaaf W. van Imhoff

https://doi.org/10.3324/haematol.2011.053199

Salvage treatment with lenalidomide and dexamethasone in relapsed/refractory mantle cell lymphoma: clinical results and effects on microenvironment and neo-angiogenic biomarkers (946 Online Views)

Francesco Zaja, Stefano De Luca, Umberto Vitolo, Lorella Orsucci, Alessandro Levis, Flavia Salvi, Chiara Rusconi, Erika Ravelli, Alessandra Tucci, Chiara Bottelli, Monica Balzarotti, Ercole Brusamolino, Maurizio Bonfichi, Stefano A. Pileri, Elena Sabattini, Stefano Volpetti, Chiara Monagheddu, Angelo Vacca, Roberto Ria, Renato Fanin

https://doi.org/10.3324/haematol.2011.051813

Flavopiridol treatment of patients aged 70 or older with refractory or relapsed chronic lymphocytic leukemia is a feasible and active therapeutic approach (392 Online Views)

Deborah M. Stephens, Amy S. Ruppert, Kristie Blum, Jeffrey Jones, Joseph M. Flynn, Amy J. Johnson, Jia Ji, Mitch A. Phelps, Michael R. Grever, John C. Byrd

https://doi.org/10.3324/haematol.2011.047324