Vol. 93 No. 5 (2008): May, 2008

Secondary genomic alterations in non-Hodgkin’s lymphomas: tumor-specific profiles with impact on clinical behavior (441 Online Views)

Sílvia Beà, Elías Campo

https://doi.org/10.3324/haematol.13030

Molecular basis of thrombocytosis (715 Online Views)

Mario Cazzola

https://doi.org/10.3324/haematol.13194

Interactions between genotype and phenotype in bleeding and thrombosis (769 Online Views)

Massimo Franchini, Pier Mannuccio Mannucci

https://doi.org/10.3324/haematol.12356

Characterization of compound 584, an Abl kinase inhibitor with lasting effects (835 Online Views)

Miriam Puttini, Sara Redaelli, Loris Moretti, Stefania Brussolo, Rosalind H Gunby, Luca Mologni, Edoardo Marchesi, Loredana Cleris, Arianna Donella-Deana, Peter Drueckes, Elisa Sala, Vittorio Lucchini, Michael Kubbutat, Franca Formelli, Alfonso Zambon, Leonardo Scapozza, Carlo Gambacorti-Passerini

https://doi.org/10.3324/haematol.12212

Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts (1446 Online Views)

Elisabeth Walsby, Val Walsh, Chris Pepper, Alan Burnett, Ken Mills

https://doi.org/10.3324/haematol.12148

Comparative genome profiling across subtypes of low-grade B-cell lymphoma identifies type-specific and common aberrations that target genes with a role in B-cell neoplasia (915 Online Views)

Bibiana I. Ferreira, Juan F. García, Javier Suela, Manuela Mollejo, Francisca I. Camacho, Angel Carro, Santiago Montes, Miguel A. Piris, Juan C. Cigudosa

https://doi.org/10.3324/haematol.12221

Genomic aberrations in mantle cell lymphoma detected by interphase fluorescence in situ hybridization. Incidence and clinicopathological correlations (910 Online Views)

Sandrine Sander, Lars Bullinger, Elke Leupolt, Axel Benner, Dirk Kienle, Tiemo Katzenberger, Jörg Kalla, German Ott, Hans Konrad Müller-Hermelink, Thomas F.E. Barth, Peter Möller, Peter Lichter, Hartmut Döhner, Stephan Stilgenbauer

https://doi.org/10.3324/haematol.12330

Gain of chromosome region 18q21 including the MALT1 gene is associated with the activated B-cell-like gene expression subtype and increased BCL2 gene dosage and protein expression in diffuse large B-cell lymphoma (1511 Online Views)

Judith Dierlamm, Eva M. Murga Penas, Stefan Bentink, Swen Wessendorf, Hilmar Berger, Michael Hummel, Wolfram Klapper, Dido Lenze, Andreas Rosenwald, Eugenia Haralambieva, German Ott, Sergio B. Cogliatti, Peter Möller, Carsten Schwaenen, Harald Stein, Markus Löffler, Rainer Spang, Lorenz Trümper, Reiner Siebert, for the Deutsche Krebshilfe Network Project “Molecular Mechanisms in Malignant Lymphomas”

https://doi.org/10.3324/haematol.12057

Selective influences in the expressed immunoglobulin heavy and light chain gene repertoire in hairy cell leukemia (1297 Online Views)

Francesco Forconi, Elisa Sozzi, Davide Rossi, Surinder S. Sahota, Teresa Amato, Donatella Raspadori, Livio Trentin, Lorenzo Leoncini, Gianluca Gaidano, Francesco Lauria

https://doi.org/10.3324/haematol.12282

A de novo splice donor mutation in the thrombopoietin gene causes hereditary thrombocythemia in a Polish family (1000 Online Views)

Kun Liu, Robert Kralovics, Zbigniew Rudzki, Barbara Grabowska, Andreas S. Buser, Damla Olcaydu, Heinz Gisslinger, Ralph Tiedt, Patricia Frank, Krzysztof Okoñ, Anthonie P.C. van der Maas, Radek C. Skoda

https://doi.org/10.3324/haematol.11801

Simultaneous genotyping of coagulation factor XI type II and type III mutations by multiplex real-time polymerase chain reaction to determine their prevalence in healthy and factor XI-deficient Italians (680 Online Views)

Giorgia Zadra, Rosanna Asselta, Maria Luisa Tenchini, Giancarlo Castaman, Uri Seligsohn, Pier Mannuccio Mannucci, Stefano Duga

https://doi.org/10.3324/haematol.12180

The Italian AICE-Genetics hemophilia A database: results and correlation with clinical phenotype (2335 Online Views)

Maurizio Margaglione, Giancarlo Castaman, Massimo Morfini, Angiola Rocino, Elena Santagostino, Giuseppe Tagariello, Anna Rita Tagliaferri, Ezio Zanon, Maria Patrizia Bicocchi, Giuseppe Castaldo, Flora Peyvandi, Rosa Santacroce, Francesca Torricelli, Elvira Grandone, Pier Mannuccio Mannucci, the AICE-Genetics Study Group

https://doi.org/10.3324/haematol.12427

AB0 blood group and risk of venous or arterial thrombosis in carriers of factor V Leiden or prothrombin G20210A polymorphisms (852 Online Views)

Antonia Miñano, Adriana Ordóñez, Francisco España, José Ramón González-Porras, Ramón Lecumberri, Jordi Fontcuberta, Pilar Llamas, Francisco Marín, Amparo Estellés, Ignacio Alberca, Vicente Vicente, Javier Corral

https://doi.org/10.3324/haematol.12271

Follow-up of healthy donors receiving granulocyte colony-stimulating factor for peripheral blood progenitor cell mobilization and collection. Results of the Spanish Donor Registry (1346 Online Views)

Javier de la Rubia, Felipe de Arriba, Cristina Arbona, María J. Pascual, Concha Zamora, Andrés Insunza, Dorleta Martínez, Carmen Paniagua, Miguel A. Díaz, Miguel A. Sanz

https://doi.org/10.3324/haematol.12285

Italian Society of Hematology practice guidelines for the management of iron overload in thalassemia major and related disorders (4224 Online Views)

Emanuele Angelucci, Giovanni Barosi, Clara Camaschella, Maria Domenica Cappellini, Mario Cazzola, Renzo Galanello, Monia Marchetti, Antonio Piga, Sante Tura

https://doi.org/10.3324/haematol.12413

Deficiency of heme-regulated eIF2α kinase decreases hepcidin expression and splenic iron in HFE−/− mice (757 Online Views)

Sijin Liu, Rajasekhar N.V.S. Suragani, Anping Han, Wanting Zhao, Nancy C. Andrews, Jane-Jane Chen

https://doi.org/10.3324/haematol.12175

Cytoplasmic mutated nucleophosmin is stable in primary leukemic cells and in a xenotransplant model of NPMc+ acute myeloid leukemia in SCID mice (945 Online Views)

Brunangelo Falini, Maria Paola Martelli, Cristina Mecucci, Arcangelo Liso, Niccolò Bolli, Barbara Bigerna, Alessandra Pucciarini, Stefano Pileri, Giovanna Meloni, Massimo F. Martelli, Torsten Haferlach, Susanne Schnittger

https://doi.org/10.3324/haematol.12225

Sickle cell disease-related organ damage occurs irrespective of pain rate: implications for clinical practice (1130 Online Views)

Eduard J. van Beers, Charlotte F.J. van Tuijn, Melvin R. Mac Gillavry, Anna van der Giessen, John-John B. Schnog, Bart J. Biemond, on behalf of the CURAMA study group

https://doi.org/10.3324/haematol.12152

Anemia management in patients on peritoneal dialysis: efficacy and safety of epoetin δ (1134 Online Views)

Bruce S. Spinowitz

https://doi.org/10.3324/haematol.10985

Phospho-CRKL monitoring for the assessment of BCR-ABL activity in imatinib-resistant chronic myeloid leukemia or Ph+ acute lymphoblastic leukemia patients treated with nilotinib (1361 Online Views)

Paul La Rosée, Susanne Holm-Eriksen, Heiko Konig, Nicolai Härtel, Thomas Ernst, Julia Debatin, Martin C. Mueller, Philipp Erben, Anja Binckebanck, Lydia Wunderle, Yaping Shou, Margaret Dugan, Ruediger Hehlmann, Oliver G. Ottmann, Andreas Hochhaus

https://doi.org/10.3324/haematol.12186

Front-line treatment of Philadelphia positive chronic myeloid leukemia with imatinib and interferon-α: 5-year outcome (632 Online Views)

Francesca Palandri, Ilaria Iacobucci, Fausto Castagnetti, Nicoletta Testoni, Angela Poerio, Marilina Amabile, Massimo Breccia, Tamara Intermesoli, Francesco Iuliano, Giovanna Rege-Cambrin, Mario Tiribelli, Maurizio Miglino, Fabrizio Pane, Giuseppe Saglio, Giovanni Martinelli, Gianantonio Rosti, Michele Baccarani, on behalf of the GIMEMA Working Party on CML

https://doi.org/10.3324/haematol.12265

Clinical and demographic characteristics of Epstein-Barr virus-associated childhood Burkitt’s lymphoma in Southeastern Brazil: epidemiological insights from an intermediate risk region (725 Online Views)

Rocio Hassan, Claudete Esteves Klumb, Fabricio E. Felisbino, Deisy M. Guiretti, Lídia R. White, Claudio Gustavo Stefanoff, Mario Henrique M. Barros, Héctor N. Seuánez, Ilana R. Zalcberg

https://doi.org/10.3324/haematol.12424

A cross-sectional magnetic resonance imaging assessment of organ specific hemosiderosis in 180 thalassemia major patients in Hong Kong (658 Online Views)

Wing-Yan Au, Wynnie Wai-man Lam, Winnie W.C. Chu, Hui-Leung Yuen, Alvin Siu-Cheung Ling, Rever Chak-Ho Li, Helen Man-Hong Chan, Harold Kwok-Kuen Lee, Man-Fai Law, Herman Sung Yu Liu, Raymond Liang, Shau-Yin Ha

https://doi.org/10.3324/haematol.12367

The Janus kinase 2 (JAK2) V617F mutation in Chinese patients with chronic myeloproliferative disorders (664 Online Views)

Zhijian Xiao, Yue Zhang, Lin Li, Ling Nie, Lin Yang, Shicai Xu

https://doi.org/10.3324/haematol.12337

A prospective study of the separate predictive capabilities of 18[F]-FDG-PET and molecular response in patients with relapsed indolent non-Hodgkin’s lymphoma following treatment with iodine-131-rituximab radio-immunotherapy (377 Online Views)

Mark J. Bishton, Rodney J. Hicks, David A. Westerman, Miles H. Prince, Max Wolf, John F. Seymour

https://doi.org/10.3324/haematol.12253

Confirmation of the utility of the International Staging System and identification of a unique pattern of disease in Brazilian patients with multiple myeloma (1258 Online Views)

Vania T.M. Hungria, Angelo Maiolino, Gracia Martinez, Gisele W.B. Colleoni, Érika O.D.M. Coelho, Laís Rocha, Renata Nunes, Rosane Bittencourt, Luciana C.O. Oliveira, Rosa Malena O. Faria, Ricardo Pasquini, Sílvia M.M. Magalhães, Cármino A. Souza, Jorge V. Pinto Neto, Luciana Barreto, Elizabeth Andrade, Maria do Socorro O. Portella, Vanessa Bolejack, Brian G.M. Durie, on behalf of the International Myeloma Working Group Latin America

https://doi.org/10.3324/haematol.11637

Serum-free light chain elevation is associated with a shorter time to treatment in Waldenstrom’s macroglobulinemia (1694 Online Views)

Raphael Itzykson, Magali Le Garff-Tavernier, Sandrine Katsahian, Marie-Claude Diemert, Lucile Musset, Veronique Leblond

https://doi.org/10.3324/haematol.12107

No evidences for B-cell clonality by spectratyping analysis in patients with idiopathic thrombocytopenic purpura undergoing rituximab therapy (547 Online Views)

Eleonora Toffoletti, Francesco Zaja, Alexsia Chiarvesio, Angela Michelutti, Marta Battista, Renato Fanin

https://doi.org/10.3324/haematol.12241

A simple, novel and robust test to diagnose type I Glanzmann thrombasthenia (376 Online Views)

Manasi Vijapurkar, Kanjaksha Ghosh, Shrimati Shetty, Mary Ann McLane, Ana Maria Moura da Silva, Diego Butera

https://doi.org/10.3324/haematol.12288

A natural variant with a point mutation resulting in a homozygous Arg to His substitution at position 388 in prothrombin (432 Online Views)

Clément d’Audigier, Eric Pasmant, Odile Bournier, Yves Laurian, Marie Claude Guillin, Annie Bezeaud

https://doi.org/10.3324/haematol.12520

Surgical treatment of a foscavir-resistant atypical Cytomegalovirus pneumonia in an allogeneic stem cell transplant recipient (458 Online Views)

C. Bressollette-Bodin, A. Claver, D. Boutolleau, P. Chevallier, T. Guillaume, T. Gastinne, P. Moreau, J-L. Harousseau, B.M. Imbert-Marcille, S. Le Gouill

https://doi.org/10.3324/haematol.12199

No association of the hypercoagulable state with sickle cell disease related pulmonary hypertension (286 Online Views)

E.J. van Beers, H.M.H. Spronk, H. ten Cate, A.J. Duits, D.P.M. Brandjes, J.W.J. van Esser, B.J. Biemond, J.B. Schnog, on behalf of the CURAMA study Group

https://doi.org/10.3324/haematol.12632