CURRENT ISSUE
June, 2025
No. 110 (6)

Landmark papers in Hematology

Editorials

Review Articles

Spotlight Review

Articles

Acute Myeloid Leukemia

Bleximenib, the novel menin-KMT2A inhibitor JNJ-75276617, impairs long-term proliferation and immune evasion in acute myeloid leukemia (2273 Online Views)

Shanna M. Hogeling, Duy Minh Lê, Nikita La Rose, Min Chul Kwon, Albertus T.J. Wierenga, Fiona A.J. van den Heuvel, Vincent van den Boom, Anna Kuchnio, Ulrike Philippar, Gerwin Huls, Jan Jacob Schuringa

https://doi.org/10.3324/haematol.2024.285616

Does size matter? Center-specific characteristics and survival after allogeneic hematopoietic cell transplantation for acute myeloid leukemia: an analysis of the German Registry for Stem Cell Transplantation and Cell Therapy (1296 Online Views)

Wolfgang Bethge, Sarah Flossdorf, Franziska Hanke, Christoph Schmid, Mark Ringhoffer, Stefan Klein, Bernd Hertenstein, Johannes Schetelig, Matthias Stelljes, Thomas Schroeder, Igor Wolfgang Blau, Francis Ayuk, Matthias Eder, Robert Zeiser, Katharina Fleischhauer, Nicolaus Kröger, Peter Dreger

https://doi.org/10.3324/haematol.2024.286385

Clinical interrogation of TP53 aberrations and its impact on survival in patients with myeloid neoplasms (5566 Online Views)

Jayastu Senapati, Sanam Loghavi, Guillermo Garcia-Manero, Guillin Tang, Tapan Kadia, Nicholas J. Short, Hussein A. Abbas, Naszrin Arani, Courtney D. DiNardo, Gautam Borthakur, Naveen Pemmaraju, Betul Oran, Elizabeth Shpall, Uday Popat, Richard Champlin, Sherry Pierce, Sankalp Arora, Ghayas Issa, Musa Yilmaz, Keyur Patel, Koichi Takahashi, Guillermo Montalban-Bravo, Danielle Hammond, Fadi G. Haddad, Farhad Ravandi, Hagop M. Kantarjian, Naval G. Daver

https://doi.org/10.3324/haematol.2024.286465

Coagulation & its Disorders

FVIII peptides presented on HLA-DP and identification of an A3 domain peptide binding with high affinity to the commonly expressed HLA-DP4 (1112 Online Views)

Mariarosaria Miranda, Bjarke Endel Hansen, Batoul Wehbi, Valeria Porcheddu, Floris P.J. van Alphen, Paul Kaijen, Karin Fijnvandraat, Sebastien Lacroix-Desmazes, Maartje van den Biggelaar, Bernard Maillere, Jan Voorberg; EDUC8 Consortium (Collaborative Group)

https://doi.org/10.3324/haematol.2024.286204

Mortality risk after cancer-related venous thromboembolism has decreased over the last three decades: the HUNT and Tromsø studies (852 Online Views)

Nikolai H. Eide, Camilla Langholm, Fridtjof B. Rinde, Nick van Es, Kristian Hveem, Sigrid K. Brækkan, John-Bjarne Hansen, Vânia M. Morelli

https://doi.org/10.3324/haematol.2024.286407

Non-Hodgkin Lymphoma

Characterization of tumor microenvironment and cell interaction patterns in testicular and diffuse large B-cell lymphomas (1777 Online Views)

Matias Autio, Oscar Brück, Marjukka Pollari, Marja-Liisa Karjalainen-Lindsberg, Klaus Beiske, Judit Mészaros Jørgensen, Harald Holte, Teijo Pellinen, Suvi-Katri Leivonen, Sirpa Leppä

https://doi.org/10.3324/haematol.2024.286267

Plasma Cell Disorders

Acid ceramidase controls proteasome inhibitor resistance and is a novel therapeutic target for the treatment of relapsed/refractory multiple myeloma (1362 Online Views)

Ryan T. Bishop, Tao Li, Praneeth Sudalagunta, Mostafa Nasr, Karl J. Nyman, Raghunandan R. Alugubelli, Mark Meads, Jeremy Frieling, Niveditha Nerlakanti, Marilena Tauro, Bin Fang, Steven Grant, John Koomen, Ariosto S. Silva, Kenneth H. Shain, Conor C. Lynch

https://doi.org/10.3324/haematol.2024.285587

Letters to the Editor

Update on long-term outcomes of a cohort of patients with TCF3::HLF-positive acute lymphoblastic leukemia treated with blinatumomab and stem cell transplantation (1171 Online Views)

Aida Zeckanovic, Brice Mouttet, Luciana Vinti, Philip Ancliff, Benoît Brethon, Gunnar Cario, Sarah Elitzur, Volkan Hazar, Joachim Kunz, Anja Möricke, Jerry Stein, Yöntem Yaman, Jochen Buechner, Magnus Aasved Hjort, David O’Connor, Angus Hodder, Jack Bartram, Julia Alten, Draga Barbaric, Gabriele Escherich, Nicolas Boissel, Loïc Vasseur, Emmanuelle Clappier, Laure Farnault, Sarah Bonnet, Katharine Patrick, Martin Schrappe, Sema Anak, André Baruchel, Franco Locatelli, Martin Stanulla, Arend von Stackelberg, Nicole Bodmer, Jean-Pierre Bourquin

https://doi.org/10.3324/haematol.2024.286111

High immunoproteasome and low constitutive proteasome subunit levels correlate with sensitivity to bortezomib-containing chemotherapy: update from the Children’s Oncology Group AALL1231 trial (805 Online Views)

Margot S. F. Roeten, Johan van Meerloo, Suzanne N. van Dijk, Zinia Kwidama, Gaye Jenkins, David T. Teachey, Meenakshi Devidas, Mignon L. Loh, Gertjan J. L. Kaspers, Sonja Zweegman, Gerrit Jansen, Terzah M. Horton, Jacqueline Cloos

https://doi.org/10.3324/haematol.2024.286171

Pre-phase treatment with rituximab and high-dose methotrexate to re-evaluate eligibility for intensive induction treatment of frail patients with central nervous system lymphoma (1270 Online Views)

Julia Wendler, Richard I. Lewis, Alexandra Kutilina, Markus Knott, Lisa Kristina Isbell, Elke Valk, Peter Borchmann, Jan-Michel Heger, Gerald Illerhaus, Elisabeth Schorb

https://doi.org/10.3324/haematol.2024.286347

H2-K1 protects murine MLL-AF9 leukemia stem cells from natural killer cell-mediated immune surveillance (836 Online Views)

Somadri Ghosh, Maria Rodriguez-Zabala, Gladys Telliam Dushime, Katrin Reinbach, Ramprasad Ramakrishnan, Ewa Sitnicka, Marcus Järås; Lymphoid Development and Regulation (Collaborative Group)

https://doi.org/10.3324/haematol.2024.286468

Myeloma cell growth suppression by osteoblast-derived extracellular vesicles: the creation of a non-permissive niche for myeloma cells by bone-forming osteoblasts (784 Online Views)

SooHa Kim, Jumpei Teramachi, Masahiro Hiasa, Ryota Amachi, Ariunzaya Bat-Erdene, Asuka Oda, Hirofumi Tenshin, Mariko Tanaka, Motosumi Nakagawa, Aiko Seki, Yoshihiko Sawa, Ken-ichi Matsuoka, Eiji Tanaka, Takeshi Harada, Tatsuya Tominaga, Masahiro Abe

https://doi.org/10.3324/haematol.2024.286554

Real-life outcome after failure to venetoclax and hypomethylating-based therapy for acute myeloid leukemia (1131 Online Views)

Carlos Jiménez-Vicente, Iago Arribas, Helena Pomares, Guillermo Ramil, Sandra Castaño-Diez, Amanda Isabel Pérez-Valencia, Antonella Luciana Sturla, Mònica López-Guerra, Alexandra Martinez-Roca, Inés Zugasti, Francesca Guijarro, Albert Cortés-Bullich, Beatriz Merchán, Ana Triguero, Inés Monge, Albert Tuca, Guadalupe Oñate, Ana Garrido, Jorge Sierra, Montserrat Arnan, Jordi Esteve, Marina Díaz-Beyá; Spanish CETLAM Group (Collaborative Group)

https://doi.org/10.3324/haematol.2024.286589

Opportunistic bone density assessment using pretreatment [18F]FDG-PET/CT identifies fracture risk in lymphoma patients undergoing corticosteroid-containing chemotherapy (641 Online Views)

Genevieve Douglas, Kane M. Nicholls, Erin Paul, Zoe Loh, Sze-Ting Lee, Kathryn L Hackman, Cherie Chiang, Niamh Waters, Geoffrey Chong, Ashvind Prabahran, Eliza A. Hawkes

https://doi.org/10.3324/haematol.2024.286618

Multinational cohort study of intracranial hemorrhage in patients with brain metastases receiving anticoagulation (1069 Online Views)

Eva N. Hamulyák, Tzu-Fei Wang, Lisa Baumann Kreuziger, Varun Iyengar, Brian J. Carney, Ann Hoeben, Berna C. Özdemir, Rosana D. Cordova Serrano, Kristen M. Sanfilippo, Shira Rozenblatt, Ludo F.M. Beenen, Shlomit Yust-Katz, Erez Halperin, Ariela Arad, Aharon Lubetsky, Marc Carrier, Benjamin Massat, Harry R. Büller, Galia Spectre, Jeffrey I. Zwicker, Avi Leader; ABC Study Group (Collaborative Group)

https://doi.org/10.3324/haematol.2024.286973

Case Reports

Very long-term remission with azacitidine in VEXAS syndrome (1134 Online Views)

Lin-Pierre Zhao, Vincent Jachiet, Olivier Kosmider, Lise Larcher, Emmanuelle Clappier, Marie Sébert, Lionel Adès, Pierre Hirsch, Thibault Mahévas, Maxime Battistella, Jean-David Bouaziz, Arsène Mekinian, Pierre Fenaux; MINHEMON FRENVEX (Collaborative Group)

https://doi.org/10.3324/haematol.2024.286641

Non-tuberculous mycobacterial infections following teclistamab in multiple myeloma (966 Online Views)

Matthew Ho, Luca Paruzzo, Janna Minehart, Teja Voruganti, Pooja Devi, Dan T. Vogl, Adam D. Cohen, Alfred L. Garfall, Adam J. Waxman, Shivani Kapur, Edward A. Stadtmauer, Sandra Susanibar Adaniya, Sarah Longworth

https://doi.org/10.3324/haematol.2024.286675

Comments

Erratum

Erratum to: Prevalence and mortality trends of hemoglobinopathies in Italy: a nationwide study (290 Online Views)

Barbara Gianesin, Frédéric B. Piel, Khaled M. Musallam, Susanna Barella, Maddalena Casale, Elena Cassinerio, Rosario Di Maggio, Antonia Gigante, Maria Rita Gamberini, Giovanna Graziadei, Roberto Lisi, Filomena Longo, Aurelio Maggio, Raffaella Origa, Annamaria Pasanisi, Silverio Perrotta, Antonio Giulio Piga, Valeria Maria Pinto, Rosamaria Rosso, Giacomo Robello, Giovanna Russo, Marco Zecca, Lucia De Franceschi, Gian Luca Forni;

https://doi.org/10.3324/haematol.2025.287581