June, 2023
No. 108 (6)

Landmark papers in Hematology

Editorials

Perspective Articles

Review Articles

Articles

Acute Myeloid Leukemia

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy (2775 Online Views)

Weiguo Zhang, Guopan Yu, Hongying Zhang, Mahesh Basyal, Charlie Ly, Bin Yuan, Vivian Ruvolo, Sujan Piya, Seemana Bhattacharya, Qi Zhang, Gautam Borthakur, Venkata Battula, Marina Konopleva, William G. Rice, Michael Andreeff

https://doi.org/10.3324/haematol.2022.280884

Bone Marrow Failure

Somatic genetic alterations predict hematological progression in GATA2 deficiency (2068 Online Views)

Laetitia Largeaud, Matthew Collin, Nils Monselet, Francois Vergez, Vincent Fregona, Lise Larcher, Pierre Hirsch, Nicolas Duployez, Audrey Bidet, Isabelle Luquet, Jacinta Bustamante, Stephanie Dufrechou, Nais Prade, Marie Nolla, Camille Hamelle, Suzanne Tavitian, Christophe Habib, Mateo Meynier, Christine Bellanne-Chantelot, Jean Donadieu, Flore Sicre de Fontbrune, Claire Fieschi, Alina Ferster, Francois Delhommeau, Eric Delabesse, Marlene Pasquet

https://doi.org/10.3324/haematol.2022.282250

Cell Therapy & Immunotherapy

Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on cytomegalovirus reactivation risk after allogeneic hematopoietic stem cell transplantation (2064 Online Views)

Elena Tassi, Maddalena Noviello, Pantaleo De Simone, Maria T. Lupo-Stanghellini, Matteo Doglio, Francesca Serio, Danilo Abbati, Valeria Beretta, Veronica Valtolina, Giacomo Oliveira, Sara Racca, Edoardo Campodonico, Eliana Ruggiero, Daniela Clerici, Fabio Giglio, Francesca Lorentino, Roee Dvir, Elisabetta Xue, Francesca Farina, Chiara Oltolini, Francesco Manfredi, Luca Vago, Consuelo Corti, Massimo Bernardi, Massimo Clementi, Liselotte Brix, Fabio Ciceri, Jacopo Peccatori, Raffaella Greco, Chiara Bonini

https://doi.org/10.3324/haematol.2022.280685

Therapeutic potential of fetal liver cell transplantation in hemophilia A mice (1609 Online Views)

Simone Merlin, Saicharan Akula, Alessia Cottonaro, Tamara Garcia-Leal, Luis Javier Serrano, Ester Borroni, Vakhtang Kalandadze, Rocio Galiano, Chiara Borsotti, Antonio Liras, María José Sanchez, Antonia Follenzi

https://doi.org/10.3324/haematol.2022.282001

Chronic Myeloid Leukemia

Differential inhibition of T-cell receptor and STAT5 signaling pathways determines the immunomodulatory effects of dasatinib in chronic phase chronic myeloid leukemia (1438 Online Views)

Patrick Harrington, Richard Dillon, Deepti Radia, Philippe Rousselot, Donal P. McLornan, Mark Ong, Anna Green, Alessandro Verde, Farzana Hussain, Kavita Raj, Shahram Kordasti, Claire Harrison, Hugues de Lavallade

https://doi.org/10.3324/haematol.2022.282005

Molecular response in newly diagnosed chronic-phase chronic myeloid leukemia: prediction modeling and pathway analysis (2060 Online Views)

Jerald P. Radich, Matthew Wall, Susan Branford, Catarina D. Campbell, Shalini Chaturvedi, Daniel J. DeAngelo, Michael Deininger, Justin Guinney, Andreas Hochhaus, Timothy P Hughes, Hagop M. Kantarjian, Richard A. Larson, Sai Li, Rodrigo Maegawa, Kaushal Mishra, Vanessa Obourn, Javier Pinilla-Ibarz, Das Purkayastha, Islam Sadek, Giuseppe Saglio, Alok Shrestha, Brian S. White, Brian J. Druker

https://doi.org/10.3324/haematol.2022.281878

Coagulation & its Disorders

Complement protein C3a enhances adaptive immune responses towards FVIII products (1433 Online Views)

Eva Ringler, Samira Ortega Iannazzo, Jessica Herzig, Lisa M. Weiss, Martina Anzaghe, Lilija Miller, Zoe Waibler

https://doi.org/10.3324/haematol.2022.281762

Non-Hodgkin Lymphoma

ALK-negative anaplastic large cell lymphoma with DUSP22 rearrangement has distinctive disease characteristics with better progression-free survival: a LYSA study (1729 Online Views)

David Sibon, Bettina Bisig, Christophe Bonnet, Elsa Poullot, Emmanuel Bachy, Doriane Cavalieri, Virginie Fataccioli, Cloe Bregnard, Fanny Drieux, Julie Bruneau, Francois Lemonnier, Aurelie Dupuy, Celine Bossard, Marie Parrens, Krimo Bouabdallah, Nicolas Ketterer, Gregoire Berthod, Anne Cairoli, Gandhi Damaj, Olivier Tournilhac, Jean-Philippe Jais, Philippe Gaulard, Laurence de Leval

https://doi.org/10.3324/haematol.2022.281442

DUSP22 rearrangement is associated with a distinctive immunophenotype but not outcome in patients with systemic ALK-negative anaplastic large cell lymphoma (1336 Online Views)

Lianqun Qiu, Guilin Tang, Shaoying Li, Francisco Vega, Pei Lin, Sa A. Wang, Wei Wang, Swaminathan P. Iyer, Luis Malpica, Roberto N. Miranda, Sergej Konoplev, Zhenya Tang, Hong Fang, L. Jeffrey Medeiros, Jie Xu

https://doi.org/10.3324/haematol.2022.281222

Targeting glutaminase is therapeutically effective in ibrutinib-resistant mantle cell lymphoma (2549 Online Views)

Lingzhi Li, Lei Nie, Alexa Jordan, Qingsong Cai, Yang Liu, Yijing Li, Yuxuan Che, Jovanny Vargas, Zhihong Chen, Angela Leeming, Wei Wang, Yixin Yao, Michael Wang, Vivian Changying Jiang

https://doi.org/10.3324/haematol.2022.281538

Plasma Cell Disorders

High-dose carfilzomib achieves superior anti-tumor activity over low-dose and recaptures response in relapsed/refractory multiple myeloma resistant to lowdose carfilzomib by co-inhibiting the β2 and β1 subunits of the proteasome complex (2038 Online Views)

Xiang Zhou, Andrej Besse, Jessica Peter, Maximilian Johannes Steinhardt, Cornelia Vogt, Silvia Nerreter, Eva Teufel, Emilia Stanojkovska, Xianghui Xiao, Hannah Hornburger, Larissa Haertle, Max Mendez Lopez, Umair Munawar, Angela Riedel, Seungbin Han, Elmer Maurits, Herman S. Overkleeft, Bogdan Florea, Hermann Einsele, K. Martin Kortüm, Christoph Driessen, Lenka Besse, Leo Rasche

https://doi.org/10.3324/haematol.2022.282225

Improved survival in myeloma patients–a nationwide registry study of 4,647 patients ≥75 years treated in Denmark and Sweden (1764 Online Views)

Kari Lenita Falck Moore, Ingemar Turesson, Anna Genell, Tobias W. Klausen, Dorota Knut-Bojanowska, Louise Redder, Ingigerdur Sverrisdottir, Jonathan Thorsen, Annette J. Vangsted, Cecilie H. Blimark

https://doi.org/10.3324/haematol.2021.280424

Red Cell Biology & its Disorders

Comprehensive in silico and functional studies for classification of EPAS1/HIF2A genetic variants identified in patients with erythrocytosis (1590 Online Views)

Valéna Karaghiannis, Darko Maric, Céline Garrec, Nada Maaziz, Alexandre Buffet, Loïc Schmitt, Vincent Antunes, Fabrice Airaud, Bernard Aral, Amandine Le Roy, Sébastien Corbineau, Lamisse Mansour-Hendili, Valentine Lesieur, Antoine Rimbert, Fabien Laporte, Marine Delamare, Minke Rab, Stéphane Bézieau, Bruno Cassinat, Frédéric Galacteros, Anne-Paule Gimenez-Roqueplo, Nelly Burnichon, Holger Cario, Richard van Wijk, Celeste Bento, François Girodon, David Hoogewijs, Betty Gardie

https://doi.org/10.3324/haematol.2022.281698

Letters to the Editor

Age- and gender-matched controls needed for platelet-based biomarker studies (1121 Online Views)

Siamack Sabrkhany, Marijke J.E. Kuijpers, Sander M.J. van Kuijk, Arjan W. Griffioen, Mirjam G.A. oude Egbrink

https://doi.org/10.3324/haematol.2022.281726

IELSG40/CLEO phase II trial of clarithromycin and lenalidomide in relapsed/refractory extranodal marginal zone lymphoma (1312 Online Views)

Maria Cristina Pirosa, Marianna Sassone, Barbara Kiesewetter, Armando Lopez Guillermo, Liliana Devizzi, Eva Domingo Domènech, Alessandra Tucci, Donato Mannina, Michele Merli, Antonio Salar, Carlo Visco, Fabiana Esposito, Luisella Bonomini, Emanuele Zucca, Andrés J. M. Ferreri, Markus Raderer

https://doi.org/10.3324/haematol.2022.281963

Allogeneic hematopoietic cell transplant for hairy cell leukemia: EBMT experience (991 Online Views)

Dai Chihara, Luuk Gras, Nienke Zinger, Nicolaus Kröger, Jiri Mayer, Jakob Passweg, Régis Peffault de Latour, Jenny Byrne, William Krüger, Jan-Paul Bohn, Uwe Platzbecker, Igor Wolfgang Blau, Francesca Bonifazi, Grzegorz Helbig, Andrew McDonald, Martin Mistrik, Mohamad Mohty, Ron Ram, Jaime Sanz, Carlos Vallejo Llamas, Robert J. Kreitman, Patrick J. Hayden, Donal McLornan, Olivier Tournilhac, Michel van Gelder, Ibrahim Yakoub-Agha

https://doi.org/10.3324/haematol.2022.281754

Light chain amyloidosis associated with Waldenström macroglobulinemia: treatment and survival outcomes (1889 Online Views)

Joshua N. Gustine, Raphael E. Szalat, Andrew Staron, Tracy Joshi, Lisa Mendelson, J. Mark Sloan, Vaishali Sanchorawala

https://doi.org/10.3324/haematol.2022.282264

Patient-reported fatigue and pain in Erdheim-Chester disease: a registry-based, mixed methods study (999 Online Views)

Anne S. Reiner, Dana Bossert, Justin J. Buthorn, Allison M. Sigler, Selin Gonen, Deanna Fournier, Kathleen Brewer, Jessica Corkran, Gaurav Goyal, Carl E. Allen, Kenneth L. McClain, Thomas M. Atkinson, Kathleen A. Lynch, Jun J. Mao, Katherine S. Panageas, Eli L. Diamond

https://doi.org/10.3324/haematol.2022.282287

Retrospective analysis of a cohort of 41 de novo B-cell prolymphocytic leukemia patients: impact of genetics and targeted therapies (a FILO study) (975 Online Views)

Caroline Algrin, Louis Pérol, Elise Chapiro, Lucile Baseggio, Karim Maloum, Catherine Settegrana, Jean-François Lesesve, Justine Siavellis, Alain Delmer, Anne-Sophie Michallet, Emmanuelle Ferrant, Pierre Feugier, Cécile Tomowiak, Annie Brion, David Ghez, Luc-Matthieu Fornecker, Sarah Ivanoff, Stéphanie Struski, Laurent Sutton, Isabelle Radford-Weiss, Virginie Eclache, Christine Lefebvre, Véronique Leblond, Florence Nguyen-Khac, Damien Roos-Weil

https://doi.org/10.3324/haematol.2022.282162

End-of-treatment PET in early-stage Hodgkin lymphoma: valuable in addition to interim PET (964 Online Views)

Karan L. Chohan, Jason R. Young, Scott Lester, Muhamad Alhaj Moustafa, Allison Rosenthal, Han W. Tun, Bradford S. Hoppe, Patrick B. Johnston, Ivana N. Micallef, Thomas M. Habermann, Stephen M. Ansell

https://doi.org/10.3324/haematol.2022.282115

Case Reports

Sirolimus as frontline therapy for PTEN-mutated histiocytic sarcoma (1065 Online Views)

Karan L. Chohan, Jithma P. Abeykoon, Jason R. Young, W. Oliver Tobin, Mathew J. Koster, Mithun V. Shah, Jay H. Ryu, Robert Vassallo, Karen L. Rech., Aishwarya Ravindran, Gaurav Goyal, Ronald S. Go, N. Nora Bennani

https://doi.org/10.3324/haematol.2022.282207

Clinical response to dabrafenib and chemotherapy in clonally-related histiocytosis and acute lymphoblastic leukemia (4725 Online Views)

Gervaise Hubert, Henrique Bittencourt, Caroline Laverdière, Pierre Teira, Sonia Cellot, Sylvie Langlois, Alexandre Rouette, Thomas Sontag, Daniel Sinnett, Dorothée Dal-Soglio, Sophie Turpin, Thai Hoa Tran

https://doi.org/10.3324/haematol.2022.281926