April, 2018
No. 103 (4)

Editorials

Review Articles

Articles

Red Cell Biology & its Disorders

New pathogenic mechanisms induced by germline erythropoietin receptor mutations in primary erythrocytosis (279 Online Views)

Florence Pasquier, Caroline Marty, Thomas Balligand, Frédérique Verdier, Sarah Grosjean, Vitalina Gryshkova, Hana Raslova, Stefan N. Constantinescu, Nicole Casadevall, William Vainchenker, Christine Bellanné-Chantelot, Isabelle Plo

https://doi.org/10.3324/haematol.2017.176370

Bone Marrow Failure

Involvement of hepcidin in iron metabolism dysregulation in Gaucher disease (367 Online Views)

Thibaud Lefebvre, Niloofar Reihani, Raed Daher, Thierry Billette de Villemeur, Nadia Belmatoug, Christian Rose, Yves Colin-Aronovicz, Hervé Puy, Caroline Le Van Kim, Mélanie Franco, Zoubida Karim

https://doi.org/10.3324/haematol.2017.177816

Myelodysplastic Syndromes

Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome (259 Online Views)

Michael J. Kraakman, Helene L. Kammoun, Dragana Dragoljevic, Annas Al-Sharea, Man K.S. Lee, Michelle C. Flynn, Christian J. Stolz, Andrew A. Guirguis, Graeme I. Lancaster, Jaye Chin-Dusting, David J. Curtis, Andrew J. Murphy

https://doi.org/10.3324/haematol.2017.181958

Myeloproliferative Disorders

Non-adherence to treatment with cytoreductive and/or antithrombotic drugs is frequent and associated with an increased risk of complications in patients with polycythemia vera or essential thrombocythemia (OUEST study) (173 Online Views)

Ronan Le Calloch, Karine Lacut, Christelle Le Gall-Ianotto, Emmanuel Nowak, Morgane Abiven, Adrian Tempescul, Florence Dalbies, Jean-Richard Eveillard, Valérie Ugo, Stéphane Giraudier, Gaëlle Guillerm, Eric Lippert, Christian Berthou, Jean-Christophe Ianotto

https://doi.org/10.3324/haematol.2017.180448

Acute Myeloid Leukemia

Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome (336 Online Views)

Aniththa Thivakaran, Lacramioara Botezatu, Judith M. Hönes, Judith Schütte, Lothar Vassen, Yahya S. Al-Matary, Pradeep Patnana, Amos Zeller, Michael Heuser, Felicitas Thol, Razif Gabdoulline, Nadine Olberding, Daria Frank, Marina Suslo, Renata Köster, Klaus Lennartz, Andre Görgens, Bernd Giebel, Bertram Opalka, Ulrich Dührsen, Cyrus Khandanpour

https://doi.org/10.3324/haematol.2017.167288

Acute Lymphoblastic Leukemia

Dynamic clonal progression in xenografts of acute lymphoblastic leukemia with intrachromosomal amplification of chromosome 21 (349 Online Views)

Paul. B. Sinclair, Helen H. Blair, Sarra L. Ryan, Lars Buechler, Joanna Cheng, Jake Clayton, Rebecca Hanna, Shaun Hollern, Zoe Hawking, Matthew Bashton, Claire J. Schwab, Lisa Jones, Lisa J. Russell, Helen Marr, Peter Carey, Christina Halsey, Olaf Heidenreich, Anthony V. Moorman, Christine J. Harrison

https://doi.org/10.3324/haematol.2017.172304

Complications in Hematology

Prevalence and characteristics of metabolic syndrome in adults from the French childhood leukemia survivors’ cohort: a comparison with controls from the French population (266 Online Views)

Claire Oudin, Julie Berbis, Yves Bertrand, Camille Vercasson, Frédérique Thomas, Pascal Chastagner, Stéphane Ducassou, Justyna Kanold, Marie-Dominique Tabone, Catherine Paillard, Marilyne Poirée, Dominique Plantaz, Jean-Hugues Dalle, Virginie Gandemer, Sandrine Thouvenin, Nicolas Sirvent, Paul Saultier, Sophie Béliard, Guy Leverger, André Baruchel, Pascal Auquier, Bruno Pannier, Gérard Michel

https://doi.org/10.3324/haematol.2017.176123

Hodgkin Lymphoma

CD83 is a new potential biomarker and therapeutic target for Hodgkin lymphoma (354 Online Views)

Ziduo Li, Xinsheng Ju, Kenneth Lee, Candice Clarke, Jennifer L. Hsu, Edward Abadir, Christian E. Bryant, Suzanne Pears, Neroli Sunderland, Scott Heffernan, Annemarie Hennessy, Tsun-Ho Lo, Geoffrey A. Pietersz, Fiona Kupresanin, Phillip D. Fromm, Pablo A. Silveira, Con Tsonis, Wendy A. Cooper, Ilona Cunningham, Christina Brown, Georgina J. Clark, Derek N.J. Hart

https://doi.org/10.3324/haematol.2017.178384

Non-Hodgkin Lymphoma

Histone modifier gene mutations in peripheral T-cell lymphoma not otherwise specified (544 Online Views)

Meng-Meng Ji, Yao-Hui Huang, Jin-Yan Huang, Zhao-Fu Wang, Di Fu, Han Liu, Feng Liu, Christophe Leboeuf, Li Wang, Jing Ye, Yi-Ming Lu, Anne Janin, Shu Cheng, Wei-Li Zhao

https://doi.org/10.3324/haematol.2017.182444

Chronic Lymphocytic Leukemia

Tumor necrosis factor receptor signaling is a driver of chronic lymphocytic leukemia that can be therapeutically targeted by the flavonoid wogonin (209 Online Views)

Claudia Dürr, Bola S. Hanna, Angela Schulz, Fabienne Lucas, Manuela Zucknick, Axel Benner, Andrew Clear, Sibylle Ohl, Selcen Öztürk, Thorsten Zenz, Stephan Stilgenbauer, Min Li-Weber, Peter H. Krammer, John G. Gribben, Peter Lichter, Martina Seiffert

https://doi.org/10.3324/haematol.2017.177808

Chronic Lymphoblastic Leukemia

Rituximab plus bendamustine or chlorambucil for chronic lymphocytic leukemia: primary analysis of the randomized, open-label MABLE study (775 Online Views)

Anne-Sophie Michallet, Melih Aktan, Wolfgang Hiddemann, Osman Ilhan, Peter Johansson, Kamel Laribi, Balkis Meddeb, Carol Moreno, João Raposo, Anna Schuh, Ali Ünal, Tom Widenius, Alf Bernhardt, Kerstin Kellershohn, Dimitri Messeri, Stuart Osborne, Véronique Leblond

https://doi.org/10.3324/haematol.2017.170480

Plasma Cell Disorders

Modeling multiple myeloma-bone marrow interactions and response to drugs in a 3D surrogate microenvironment (578 Online Views)

Daniela Belloni, Silvia Heltai, Maurilio Ponzoni, Antonello Villa, Barbara Vergani, Lorenza Pecciarini, Magda Marcatti, Stefania Girlanda, Giovanni Tonon, Fabio Ciceri, Federico Caligaris-Cappio, Marina Ferrarini, Elisabetta Ferrero

https://doi.org/10.3324/haematol.2017.167486

Stem Cell Trasplantation

Tocilizumab, tacrolimus and methotrexate for the prevention of acute graft-versus-host disease: low incidence of lower gastrointestinal tract disease (296 Online Views)

William R. Drobyski, Aniko Szabo, Fenlu Zhu, Carolyn Keever-Taylor, Kyle M. Hebert, Renee Dunn, Sharon Yim, Bryon Johnson, Anita D’Souza, Mary Eapen, Timothy S. Fenske, Parameswaran Hari, Mehdi Hamadani, Mary M. Horowitz, J. Douglas Rizzo, Wael Saber, Nirav Shah, Bronwen Shaw, Marcelo Pasquini

https://doi.org/10.3324/haematol.2017.183434

Hemostasis

Macrophage scavenger receptor SR-AI contributes to the clearance of von Willebrand factor (218 Online Views)

Nikolett Wohner, Vincent Muczynski, Amel Mohamadi, Paulette Legendre, Valérie Proulle, Gabriel Aymé, Olivier D. Christophe, Peter J. Lenting, Cécile V. Denis, Caterina Casari

https://doi.org/10.3324/haematol.2017.175216

Coagulation & its Disorders

A three-year prospective study of the presentation and clinical outcomes of major bleeding episodes associated with oral anticoagulant use in the UK (ORANGE study) (322 Online Views)

Laura Green, Joachim Tan, Joan K Morris, Raza Alikhan, Nicola Curry, Tamara Everington, Rhona Maclean, Khalid Saja, Simon Stanworth, Campbell Tait, Peter MacCallum

https://doi.org/10.3324/haematol.2017.182220

Online Only Articles

Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease (389 Online Views)

Mark R. Hanudel, Maxime Rappaport, Kristine Chua, Victoria Gabayan, Bo Qiao, Grace Jung, Isidro B. Salusky, Tomas Ganz, Elizabeta Nemeth

https://doi.org/10.3324/haematol.2017.181743

Emergence and evolution of TP53 mutations are key features of disease progression in myelodysplastic patients with lower-risk del(5q) treated with lenalidomide (388 Online Views)

Laurence Lodé, Audrey Ménard, Laurent Flet, Steven Richebourg, Marion Loirat, Marion Eveillard, Yannick Le Bris, Catherine Godon, Olivier Theisen, Anne-Laure Gagez, Guillaume Cartron, Thérèse Commes-Maerten, Bruno Villemagne, Odile Luycx, Pascal Godmer, Catherine Pellat-Deceunynck, Thierry Soussi, Marie C. Béné, Jacques Delaunay, Pierre Peterlin

https://doi.org/10.3324/haematol.2017.181404

Impact of histological grading on survival in the SWOG S0016 follicular lymphoma cohort (218 Online Views)

Lisa M. Rimsza, Hongli Li, Rita M. Braziel, Catherine M. Spier, Daniel O. Persky, Jennifer Dunlap, Michael LeBlanc, Nancy Bartlett, John P. Leonard, Sonali M. Smith, Oliver W. Press, Jonathan W. Friedberg

https://doi.org/10.3324/haematol.2017.175059

No improvement in long-term survival over time for chronic lymphocytic leukemia patients in stereotyped subsets #1 and #2 treated with chemo(immuno)therapy (284 Online Views)

Panagiotis Baliakas, Mattias Mattsson, Anastasia Hadzidimitriou, Eva Minga, Andreas Agathangelidis, Lesley-Ann Sutton, Lydia Scarfo, Zadie Davis, Xiao-Jie Yan, Karla Plevova, Yorick Sandberg, Fie J. Vojdeman, Tatiana Tzenou, Charles C. Chu, Silvio Veronese, Larry Mansouri, Karin E Smedby, Véronique Giudicelli, Florence Nguyen-Khac, Panagiotis Panagiotidis, Gunnar Juliusson, Achilles Anagnostopoulos, Marie-Paule Lefranc, Livio Trentin, Mark Catherwood, Marco Montillo, Carsten U. Niemann, Anton W. Langerak, Sarka Pospisilova, Niki Stavroyianni, Nicholas Chiorazzi, David Oscier, Diane F Jelinek, Tait Shanafelt, Nikos Darzentas, Chrysoula Belessi, Frederic Davi, Paolo Ghia, Richard Rosenquist, Kostas Stamatopoulos

https://doi.org/10.3324/haematol.2017.182634

Rapid hematologic responses improve outcomes in patients with very advanced (stage IIIb) cardiac immunoglobulin light chain amyloidosis (186 Online Views)

Richa Manwani, Darren Foard, Shameem Mahmood, Sajitha Sachchithanantham, Thirusha Lane, Cristina Quarta, Taryn Youngstein, Tamer Rezk, Helen J Lachmann, Julian D. Gillmore, Marianna Fontana, Carol Whelan, Philip N. Hawkins, Ashutosh Wechalekar

https://doi.org/10.3324/haematol.2017.178095

Lethal neonatal bone marrow failure syndrome with multiple congenital abnormalities, including limb defects, due to a constitutional deletion of 3′ MECOM (302 Online Views)

Lars T. van der Veken, Merel C. Maiburg, Floris Groenendaal, Mariëlle E. van Gijn, Andries C. Bloem, Claudia Erpelinck, Stefan Gröschel, Mathijs A. Sanders, Ruud Delwel, Marc B. Bierings, Arjan Buijs

https://doi.org/10.3324/haematol.2017.185033

Single-agent dabrafenib for BRAFV600E-mutated histiocytosis (154 Online Views)

Ankush Bhatia, Gary Ulaner, Raajit Rampal, David M. Hyman, Omar Abdel-Wahab, Benjamin H. Durham, Ahmet Dogan, Neval Ozkaya, Mario E. Lacouture, Julio Hajdenberg, Chezi Ganzel, Eli L. Diamond

https://doi.org/10.3324/haematol.2017.185298