December, 2015
No. 100 (12)

Editorials

Review Articles

Articles

Red Cell Biology & its Disorders

Impairment of neutrophil oxidative burst in children with sickle cell disease is associated with heme oxygenase-1 (368 Online Views)

Ceri Evans, Katharine Orf, Erzsebet Horvath, Michael Levin, Josu De La Fuente, Subarna Chakravorty, Aubrey J. Cunnington

https://doi.org/10.3324/haematol.2015.128777

Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice (277 Online Views)

Derek Vang, Jinny A. Paul, Julia Nguyen, Huy Tran, Lucile Vincent, Dennis Yasuda, Nurulain T. Zaveri, Kalpna Gupta

https://doi.org/10.3324/haematol.2015.128736

Platelet Biology & its Disorders

Hemoglobin interaction with GP1bα induces platelet activation and apoptosis: a novel mechanism associated with intravascular hemolysis (539 Online Views)

Rashi Singhal, Gowtham K. Annarapu, Ankita Pandey, Sheetal Chawla, Amrita Ojha, Avinash Gupta, Miguel A. Cruz, Tulika Seth, Prasenjit Guchhait

https://doi.org/10.3324/haematol.2015.132183

Bone Marrow Failure

Identification of novel microRNA signatures linked to acquired aplastic anemia (286 Online Views)

Kohei Hosokawa, Pawel Muranski, Xingmin Feng, Keyvan Keyvanfar, Danielle M. Townsley, Bogdan Dumitriu, Jichun Chen, Sachiko Kajigaya, James G. Taylor, Christopher S. Hourigan, A. John Barrett, Neal S. Young

https://doi.org/10.3324/haematol.2015.126128

Paroxysmal nocturnal hemoglobinuria and telomere length predicts response to immunosuppressive therapy in pediatric aplastic anemia (479 Online Views)

Atsushi Narita, Hideki Muramatsu, Yuko Sekiya, Yusuke Okuno, Hirotoshi Sakaguchi, Nobuhiro Nishio, Nao Yoshida, Xinan Wang, Yinyan Xu, Nozomu Kawashima, Sayoko Doisaki, Asahito Hama, Yoshiyuki Takahashi, Kazuko Kudo, Hiroshi Moritake, Masao Kobayashi, Ryoji Kobayashi, Etsuro Ito, Hiromasa Yabe, Shouichi Ohga, Akira Ohara, Seiji Kojima

https://doi.org/10.3324/haematol.2015.132530

Acute Myeloid Leukemia

Co-administration of the mTORC1/TORC2 inhibitor INK128 and the Bcl-2/Bcl-xL antagonist ABT-737 kills human myeloid leukemia cells through Mcl-1 down-regulation and AKT inactivation (591 Online Views)

Mohamed Rahmani, Mandy Mayo Aust, Elisa Hawkins, Rebecca E. Parker, Masey Ross, Maciej Kmieciak, Leonid Borisovich Reshko, Kathryn A. Rizzo, Catherine I. Dumur, Andrea Ferreira-Gonzalez, Steven Grant

https://doi.org/10.3324/haematol.2015.130351

Acute Lymphoblastic Leukemia

Aggravated bone density decline following symptomatic osteonecrosis in children with acute lymphoblastic leukemia (306 Online Views)

Marissa A.H. den Hoed, Saskia M.F. Pluijm, Mariël L. te Winkel, Hester A. de Groot-Kruseman, Martha Fiocco, Peter Hoogerbrugge, Jan A. Leeuw, Marrie C.A. Bruin, Inge M. van der Sluis, Dorien Bresters, Maarten H. Lequin, Jan C. Roos, Anjo J.P. Veerman, Rob Pieters, Marry M. van den Heuvel-Eibrink

https://doi.org/10.3324/haematol.2015.125583

Chronic Lymphocytic Leukemia

Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib (542 Online Views)

Andrew H. Lipsky, Mohammed Z.H. Farooqui, Xin Tian, Sabrina Martyr, Ann M. Cullinane, Khanh Nghiem, Clare Sun, Janet Valdez, Carsten U. Niemann, Sarah E. M. Herman, Nakhle Saba, Susan Soto, Gerald Marti, Gulbu Uzel, Steve M. Holland, Jay N. Lozier, Adrian Wiestner

https://doi.org/10.3324/haematol.2015.126672

Hodgkin Lymphoma

Nodular lymphocyte predominant Hodgkin lymphoma: a Lymphoma Study Association retrospective study (547 Online Views)

Julien Lazarovici, Peggy Dartigues, Pauline Brice, Lucie Obéric, Isabelle Gaillard, Mathilde Hunault-Berger, Florence Broussais-Guillaumot, Emmanuel Gyan, Serge Bologna, Emmanuelle Nicolas-Virelizier, Mohamed Touati, Olivier Casasnovas, Richard Delarue, Frédérique Orsini-Piocelle, Aspasia Stamatoullas, Jean Gabarre, Luc-Matthieu Fornecker, Thomas Gastinne, Fréderic Peyrade, Virginie Roland, Emmanuel Bachy, Marc André, Nicolas Mounier, Christophe Fermé

https://doi.org/10.3324/haematol.2015.133025

Non-Hodgkin Lymphoma

Bing-Neel syndrome, a rare complication of Waldenström macroglobulinemia: analysis of 44 cases and review of the literature. A study on behalf of the French Innovative Leukemia Organization (FILO). (3018 Online Views)

Laurence Simon, Aikaterini Fitsiori, Richard Lemal, Jehan Dupuis, Benjamin Carpentier, Laurys Boudin, Anne Corby, Thérèse Aurran-Schleinitz, Lauris Gastaud, Alexis Talbot, Stéphane Leprêtre, Béatrice Mahe, Camille Payet, Carole Soussain, Charlotte Bonnet, Laure Vincent, Séverine Lissandre, Raoul Herbrecht, Stéphane Kremer, Véronique Leblond, Luc-Matthieu Fornecker

https://doi.org/10.3324/haematol.2015.133744

Online Only Articles

Homozygous knockout of the piezo1 gene in the zebrafish is not associated with anemia (287 Online Views)

Boris E. Shmukler, Nicholas C. Huston, Jonathan N. Thon, Chih-Wen Ni, George Kourkoulis, Nathan D. Lawson, Barry H. Paw, Seth L. Alper

https://doi.org/10.3324/haematol.2015.132449

Karyotype evolution and acquisition of FLT3 or RAS pathway alterations drive progression of myelodysplastic syndrome to acute myeloid leukemia (333 Online Views)

Manja Meggendorfer, Andreia de Albuquerque, Niroshan Nadarajah, Tamara Alpermann, Wolfgang Kern, Kimberly Steuer, Karolína Perglerová, Claudia Haferlach, Susanne Schnittger, Torsten Haferlach

https://doi.org/10.3324/haematol.2015.127985

Abnormal Hedgehog pathway in myelodysplastic syndrome and its impact on patients’ outcome (360 Online Views)

Juliana M. Xavier-Ferrucio, Fernando Vieira Pericole, Matheus Rodrigues Lopes, Paulo Latuf-Filho, Karin Spät Albino Barcellos, Amanda Inácio Dias, Paula de Melo Campos, Fabiola Traina, Jose Vassallo, Sara Teresinha Olalla Saad, Patricia Favaro

https://doi.org/10.3324/haematol.2015.124040

A phase II multi-center trial of pentostatin plus cyclophosphamide with ofatumumab in older previously untreated chronic lymphocytic leukemia patients (221 Online Views)

Alessandra Tedeschi, Davide Rossi, Marina Motta, Giulia Quaresmini, Marianna Rossi, Marta Coscia, Antonella Anastasia, Fausto Rossini, Agostino Cortelezzi, Guido Nador, Lydia Scarfò, Roberto Cairoli, Anna Maria Frustaci, Daniela Dalceggio, Paola Picardi, Lorenzo De Paoli, Ester Orlandi, Alessandro Rambaldi, Massimo Massaia, Gianluca Gaidano, Marco Montillo

https://doi.org/10.3324/haematol.2015.132035

Reduced relapse rate in upfront tandem autologous/reduced-intensity allogeneic transplantation in multiple myeloma only results in borderline non-significant prolongation of progression-free but not overall survival (139 Online Views)

Henk M. Lokhorst, Bronno van der Holt, Jan J. Cornelissen, Marie José Kersten, Marinus van Oers, Reinier Raymakers, Monique C. Minnema, Sonja Zweegman, Gerard Bos, Nicolaas Schaap, Shulamiet Wittebol, Okke de Weerdt, Rianne Ammerlaan, Pieter Sonneveld

https://doi.org/10.3324/haematol.2015.128728

Growth differentiation factor 15 (GDF15) promotes osteoclast differentiation and inhibits osteoblast differentiation and high serum GDF15 levels are associated with multiple myeloma bone disease (362 Online Views)

Marita Westhrin, Siv Helen Moen, Toril Holien, Anne Kærsgaard Mylin, Lene Heickendorff, Oddrun Elise Olsen, Anders Sundan, Ingemar Turesson, Peter Gimsing, Anders Waage, Therese Standal

https://doi.org/10.3324/haematol.2015.124511

Clinical profile associated with infections in patients with chronic lymphocytic leukemia. Protective role of immunoglobulin replacement therapy (207 Online Views)

Andrea Visentin, Nicolò Compagno, Francesco Cinetto, Silvia Imbergamo, Renato Zambello, Francesco Piazza, Gianpietro Semenzato, Livio Trentin, Carlo Agostini

https://doi.org/10.3324/haematol.2015.126763