October, 2015
No. 100 (10)

Editorials

Review Articles

Articles

Hematopoiesis

Red Cell Biology & its Disorders

Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy (303 Online Views)

Santosh L. Saraf, Xu Zhang, Binal Shah, Tamir Kanias, Krishnamurthy P. Gudehithlu, Rick Kittles, Roberto F. Machado, Jose A.L. Arruda, Mark T. Gladwin, Ashok K. Singh, Victor R. Gordeuk

https://doi.org/10.3324/haematol.2015.124875

Bone Marrow Failure

Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes (275 Online Views)

Noemi A. Zambetti, Eric M. J. Bindels, Paulina M. H. Van Strien, Marijke G. Valkhof, Maria N. Adisty, Remco M. Hoogenboezem, Mathijs A. Sanders, Johanna M. Rommens, Ivo P. Touw, Marc H. G. P. Raaijmakers

https://doi.org/10.3324/haematol.2015.131573

Acute Myeloid Leukemia

Panobinostat as part of induction and maintenance for elderly patients with newly diagnosed acute myeloid leukemia: phase Ib/II panobidara study (202 Online Views)

Enrique M. Ocio, Pilar Herrera, María-Teresa Olave, Nerea Castro, José A. Pérez-Simón, Salut Brunet, Albert Oriol, Marta Mateo, Miguel-Ángel Sanz, Javier López, Pau Montesinos, María-Carmen Chillón, María-Isabel Prieto-Conde, María Díez-Campelo, Marcos González, María-Belén Vidriales, María-Victoria Mateos, Jesús F. San Miguel

https://doi.org/10.3324/haematol.2015.129577

Acute Lymphoblastic Leukemia

Targeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemia (509 Online Views)

Carmen Vicente, Claire Schwab, Michaël Broux, Ellen Geerdens, Sandrine Degryse, Sofie Demeyer, Idoya Lahortiga, Alannah Elliott, Lucy Chilton, Roberta La Starza, Cristina Mecucci, Peter Vandenberghe, Nicholas Goulden, Ajay Vora, Anthony V. Moorman, Jean Soulier, Christine J. Harrison, Emmanuelle Clappier, Jan Cools

https://doi.org/10.3324/haematol.2015.130179

CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol (220 Online Views)

Farzaneh Ghazavi, Emmanuelle Clappier, Tim Lammens, Stefan Suciu, Aurélie Caye, Samira Zegrari, Marleen Bakkus, Nathalie Grardel, Yves Benoit, Yves Bertrand, Odile Minckes, Vitor Costa, Alina Ferster, Françoise Mazingue, Geneviève Plat, Emmanuel Plouvier, Marilyne Poirée, Anne Uyttebroeck, Jutte van der Werff-ten Bosch, Karima Yakouben, Hetty Helsmoortel, Magali Meul, Nadine Van Roy, Jan Philippé, Frank Speleman, Hélène Cavé, Pieter Van Vlierberghe, Barbara De Moerloose

https://doi.org/10.3324/haematol.2015.126953

Hodgkin Lymphoma

Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis (267 Online Views)

Frederik Wein, Teresa Otto, Pascal Lambertz, Joachim Fandrey, Martin-Leo Hansmann, Ralf Küppers

https://doi.org/10.3324/haematol.2015.127498

Plasma Cell Disorders

Cytogenetics and long-term survival of patients with refractory or relapsed and refractory multiple myeloma treated with pomalidomide and low-dose dexamethasone (393 Online Views)

Meletios A. Dimopoulos, Katja C. Weisel, Kevin W. Song, Michel Delforge, Lionel Karlin, Hartmut Goldschmidt, Philippe Moreau, Anne Banos, Albert Oriol, Laurent Garderet, Michele Cavo, Valentina Ivanova, Adrian Alegre, Joaquin Martinez-Lopez, Christine Chen, Andrew Spencer, Stefan Knop, Nizar J. Bahlis, Christoph Renner, Xin Yu, Kevin Hong, Lars Sternas, Christian Jacques, Mohamed H. Zaki, Jesus F. San Miguel

https://doi.org/10.3324/haematol.2014.117077

Impact of prior treatment and depth of response on survival in MM-003, a randomized phase 3 study comparing pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone in relapsed/refractory multiple myeloma (370 Online Views)

Jesus F. San Miguel, Katja C. Weisel, Kevin W. Song, Michel Delforge, Lionel Karlin, Hartmut Goldschmidt, Philippe Moreau, Anne Banos, Albert Oriol, Laurent Garderet, Michele Cavo, Valentina Ivanova, Adrian Alegre, Joaquin Martinez-Lopez, Christine Chen, Christoph Renner, Nizar Jacques Bahlis, Xin Yu, Terri Teasdale, Lars Sternas, Christian Jacques, Mohamed H. Zaki, Meletios A. Dimopoulos

https://doi.org/10.3324/haematol.2015.125864

Large registry analysis to accurately define second malignancy rates and risks in a well-characterized cohort of 744 consecutive multiple myeloma patients followed-up for 25 years (229 Online Views)

Monika Engelhardt, Gabriele Ihorst, Ola Landgren, Milena Pantic, Heike Reinhardt, Johannes Waldschmidt, Annette M. May, Martin Schumacher, Martina Kleber, Ralph Wäsch

https://doi.org/10.3324/haematol.2015.127548

The novel β2-selective proteasome inhibitor LU-102 synergizes with bortezomib and carfilzomib to overcome proteasome inhibitor resistance of myeloma cells (243 Online Views)

Marianne Kraus, Juergen Bader, Paul P. Geurink, Emily S. Weyburne, Anne C. Mirabella, Tobias Silzle, Tamer B. Shabaneh, Wouter A. van der Linden, Gerjan de Bruin, Sarah R. Haile, Eva van Rooden, Christina Appenzeller, Nan Li, Alexei F. Kisselev, Herman Overkleeft, Christoph Driessen

https://doi.org/10.3324/haematol.2014.109421

Stem Cell Transplantation

Better allele-level matching improves transplant-related mortality after double cord blood transplantation (379 Online Views)

Betül Oran, Kai Cao, Rima M. Saliba, Katayoun Rezvani, Marcos de Lima, Sairah Ahmed, Chitra M. Hosing, Uday R. Popat, Yudith Carmazzi, Partow Kebriaei, Yago Nieto, Gabriela Rondon, Dana Willis, Nina Shah, Simrit Parmar, Amanda Olson, Brandt Moore, David Marin, Rohtesh Mehta, Marcelo Fernández-Viña, Richard E. Champlin, Elizabeth J. Shpall

https://doi.org/10.3324/haematol.2015.127787

Guidelines

European Myeloma Network Guidelines for the Management of Multiple Myeloma-related Complications (1488 Online Views)

Evangelos Terpos, Martina Kleber, Monika Engelhardt, Sonja Zweegman, Francesca Gay, Efstathios Kastritis, Niels W.C.J. van de Donk, Benedetto Bruno, Orhan Sezer, Annemiek Broijl, Sara Bringhen, Meral Beksac, Alessandra Larocca, Roman Hajek, Pellegrino Musto, Hans Erik Johnsen, Fortunato Morabito, Heinz Ludwig, Michele Cavo, Hermann Einsele, Pieter Sonneveld, Meletios A. Dimopoulos, Antonio Palumbo

https://doi.org/10.3324/haematol.2014.117176

Online Only Articles

Hydroxyurea treatment does not increase blood viscosity and improves red blood cell rheology in sickle cell anemia (212 Online Views)

Nathalie Lemonne, Keyne Charlot, Xavier Waltz, Samir K. Ballas, Yann Lamarre, Ketty Lee, Régine Hierso, Catherine Connes, Maryse Etienne-Julan, Marc Romana, Philippe Connes

https://doi.org/10.3324/haematol.2015.130435

Anti-KEL sera prevents alloimmunization to transfused KEL RBCs in a murine model (105 Online Views)

Sean R. Stowell, C. Maridith Arthur, Kathryn R. Girard-Pierce, Harold C. Sullivan, Manjula Santhanakrishnan, Prabitha Natarajan, Seema R. Patel, Christopher A. Tormey, James C. Zimring, Jeanne E. Hendrickson

https://doi.org/10.3324/haematol.2015.128603

GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies (265 Online Views)

Xinan Wang, Hideki Muramatsu, Yusuke Okuno, Hirotoshi Sakaguchi, Kenichi Yoshida, Nozomu Kawashima, Yinyan Xu, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Shoji Saito, Yozo Nakazawa, Taro Masunari, Tadashi Hirose, Shaimaa Elmahdi, Atsushi Narita, Sayoko Doisaki, Olfat Ismael, Hideki Makishima, Asahito Hama, Satoru Miyano, Yoshiyuki Takahashi, Seishi Ogawa, Seiji Kojima

https://doi.org/10.3324/haematol.2015.127092

Increased pressure alters plasma membrane dynamics and renders acute myeloid leukemia cells resistant to daunorubicin (76 Online Views)

Victor Sanjit Nirmalanandhan, Rose Hurren, William D. Cameron, Marcela Gronda, Aisha Shamas-Din, Lidan You, Mark D. Minden, Jonathan V. Rocheleau, Aaron D Schimmer

https://doi.org/10.3324/haematol.2015.129866

Empiric definition of eligibility criteria for clinical trials in relapsed/refractory acute myeloid leukemia: analysis of 1,892 patients from HOVON/SAKK and SWOG (102 Online Views)

Roland B. Walter, Megan Othus, Bob Löwenberg, Gert J. Ossenkoppele, Stephen H. Petersdorf, Thomas Pabst, Marie-Christiane Vekemans, Frederick R. Appelbaum, Harry P. Erba, Elihu H. Estey

https://doi.org/10.3324/haematol.2015.130013

NPM1 mutation is associated with leukemia cutis in acute myeloid leukemia with monocytic features (143 Online Views)

Marlise R. Luskin, Auris O. Huen, Sarah A. Brooks, Campbell Stewart, Christopher D. Watt, Jennifer J.D. Morrissette, David B. Lieberman, Adam Bagg, Misha Rosenbach, Alexander E. Perl

https://doi.org/10.3324/haematol.2015.129346

Primary diffuse large B-cell lymphoma associated with clonally-related monoclonal B lymphocytosis indicates a common precursor cell (150 Online Views)

Agnieszka Malecka, Anne Tierens, Ingunn Østlie, Roland Schmitz, Gunhild Trøen, Signe Spetalen, Louis M. Staudt, Erlend Smeland, Harald Holte, Jan Delabie

https://doi.org/10.3324/haematol.2015.126656

LB-ARHGDIB-1R as a novel minor histocompatibility antigen for therapeutic application (170 Online Views)

Margot J. Pont, Willemijn Hobo, Maria W. Honders, Simone A.P. van Luxemburg-Heijs, Michel G.D. Kester, Annemarie M. van Oeveren-Rietdijk, Nicolaas Schaap, Hetty C. de Boer, Cornelis A.M. van Bergen, Harry Dolstra, J.H. Frederik Falkenburg, Marieke Griffioen

https://doi.org/10.3324/haematol.2015.125021

Tandem autologous-allogeneic stem cell transplantation as a feasible and effective procedure in high-risk lymphoma patients (170 Online Views)

Roberto Crocchiolo, Luca Castagna, Sylvain Garciaz, Sabine Fürst, Jean El Cheikh, Barbara Sarina, Stefania Bramanti, Angela Granata, Andrea Vai, Samia Harbi, Lucio Morabito, Bilal Mohty, Laura Giordano, Raynier Devillier, Diane Coso, Monica Balzarotti, Christian Chabannon, Carmelo Carlo-Stella, Armando Santoro, Reda Bouabdallah, Didier Blaise

https://doi.org/10.3324/haematol.2015.129452

Transplantation of Macaca cynomolgus iPS-derived hematopoietic cells in NSG immunodeficient mice (126 Online Views)

Soumeya Abed, Alisa Tubsuwan, Porntip Chaichompoo, In Hyun Park, Alice Pailleret, Aïssa Benyoucef, Lucie Tosca, Edouard De Dreuzy, Anais Paulard, Marine Granger-Locatelli, Francis Relouzat, Stéphane Prost, Gerard Tachdjian, Suthat Fucharoen, George Q. Daley, Emmanuel Payen, Stany Chrétien, Philippe Leboulch, Leïla Maouche-Chrétien

https://doi.org/10.3324/haematol.2015.127373

Comments