September, 2014
No. 99 (9)

Editorials

Editorials & Perspectives

Review Articles

Survival analysis in hematologic malignancies: recommendations for clinicians

Julio Delgado, Arturo Pereira, Neus Villamor, Armando López-Guillermo, Ciril Rozman

https://doi.org/10.3324/haematol.2013.100784

Early lymphoid lesions: conceptual, diagnostic and clinical challenges

Karthik A. Ganapathi, Stefania Pittaluga, Oreofe O. Odejide, Arnold S. Freedman, Elaine S. Jaffe

https://doi.org/10.3324/haematol.2014.107938

Articles

In vivo effects of horse and rabbit antithymocyte globulin in patients with severe aplastic anemia

Xingmin Feng, Phillip Scheinberg, Angelique Biancotto, Olga Rios, Sarah Donaldson, Colin Wu, Haiyun Zheng, Kazuya Sato, Danielle M. Townsley, J. Philip McCoy, Neal S. Young

https://doi.org/10.3324/haematol.2014.106542

Distinct characteristics of e13a2 versus e14a2 BCR-ABL1 driven chronic myeloid leukemia under first-line therapy with imatinib

Benjamin Hanfstein, Michael Lauseker, Rüdiger Hehlmann, Susanne Saussele, Philipp Erben, Christian Dietz, Alice Fabarius, Ulrike Proetel, Susanne Schnittger, Claudia Haferlach, Stefan W. Krause, Jörg Schubert, Hermann Einsele, Mathias Hänel, Jolanta Dengler, Christiane Falge, Lothar Kanz, Andreas Neubauer, Michael Kneba, Frank Stegelmann, Michael Pfreundschuh, Cornelius F. Waller, Karsten Spiekermann, Gabriela M. Baerlocher, Markus Pfirrmann, Joerg Hasford, Wolf-Karsten Hofmann, Andreas Hochhaus, Martin C. Müller

https://doi.org/10.3324/haematol.2013.096537

Impact of MLL5 expression on decitabine efficacy and DNA methylation in acute myeloid leukemia

Haiyang Yun, Frederik Damm, Damian Yap, Adrian Schwarzer, Anuhar Chaturvedi, Nidhi Jyotsana, Michael Lübbert, Lars Bullinger, Konstanze Döhner, Robert Geffers, Samuel Aparicio, R. Keith Humphries, Arnold Ganser, Michael Heuser

https://doi.org/10.3324/haematol.2013.101386

The prognostic significance of early treatment response in pediatric relapsed acute myeloid leukemia: results of the international study Relapsed AML 2001/01

Ursula Creutzig, Martin Zimmermann, Michael N. Dworzak, Brenda Gibson, Rienk Tamminga, Jonas Abrahamsson, Shau-Yin Ha, Henrik Hasle, Alexey Maschan, Yves Bertrand, Guy Leverger, Christine von Neuhoff, Bassem Razzouk, Carmelo Rizzari, Petr Smisek, Owen P. Smith, Batia Stark, Dirk Reinhardt, Gertjan L. Kaspers

https://doi.org/10.3324/haematol.2014.104182

Efficacy of bortezomib, cyclophosphamide and dexamethasone in treatment-naïve patients with high-risk cardiac AL amyloidosis (Mayo Clinic stage III)

Arnaud Jaccard, Raymond L. Comenzo, Parameswaran Hari, Philip N. Hawkins, Murielle Roussel, Pierre Morel, Margaret Macro, Jean-Luc Pellegrin, Estibaliz Lazaro, Dania Mohty, Patrick Mercie, Olivier Decaux, Julian Gillmore, David Lavergne, Frank Bridoux, Ashutosh D. Wechalekar, Christopher P. Venner

https://doi.org/10.3324/haematol.2014.104109

Results from a clofarabine-busulfan-containing, reduced-toxicity conditioning regimen prior to allogeneic stem cell transplantation: the phase 2 prospective CLORIC trial

Patrice Chevallier, Myriam Labopin, Gérard Socié, Reza Tabrizi, Sabine Furst, Bruno Lioure, Thierry Guillaume, Jacques Delaunay, Régis Peffault de La Tour, Stéphane Vigouroux, Jean El-Cheikh, Didier Blaise, Mauricette Michallet, Karin Bilger, Noel Milpied, Philippe Moreau, Mohamad Mohty

https://doi.org/10.3324/haematol.2014.108563

Early administration of donor lymphocyte infusions upon molecular relapse after allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia: a study by the Chronic Malignancies Working Party of the EBMT

Yves Chalandon, Jakob R. Passweg, Cesare Guglielmi, Simona Iacobelli, Jane Apperley, Nicolaas P.M. Schaap, Jürgen Finke, Marie Robin, Roberta Fedele, Dominique Bron, Ibrahim Yakoub-Agha, Anja van Biezen, Theo de Witte, Nicolaus Kröger, Eduardo Olavarria

https://doi.org/10.3324/haematol.2013.100198

Increased mitochondrial apoptotic priming of human regulatory T cells after allogeneic hematopoietic stem cell transplantation

Kazuyuki Murase, Haesook T. Kim, O.R. Gregory Bascug, Yutaka Kawano, Jeremy Ryan, Ken-ichi Matsuoka, Matthew S. Davids, John Koreth, Vincent T. Ho, Corey Cutler, Philippe Armand, Edwin P. Alyea, Bruce R. Blazar, Joseph H. Antin, Robert J. Soiffer, Anthony Letai, Jerome Ritz

https://doi.org/10.3324/haematol.2014.104166

Engraftment kinetics and graft failure after single umbilical cord blood transplantation using a myeloablative conditioning regimen

Annalisa Ruggeri, Myriam Labopin, Maria Pia Sormani, Guillermo Sanz, Jaime Sanz, Fernanda Volt, Gerard Michel, Franco Locatelli, Cristina Diaz De Heredia, Tracey O’Brien, William Arcese, Anna Paola Iori, Sergi Querol, Gesine Kogler, Lucilla Lecchi, Fabienne Pouthier, Federico Garnier, Cristina Navarrete, Etienne Baudoux, Juliana Fernandes, Chantal Kenzey, Mary Eapen, Eliane Gluckman, Vanderson Rocha, Riccardo Saccardi

https://doi.org/10.3324/haematol.2014.109280

Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats

Milan Theurl, Manfred Nairz, Andrea Schroll, Thomas Sonnweber, Malte Asshoff, David Haschka, Markus Seifert, Wolfgang Willenbacher, Doris Wilflingseder, Wilfried Posch, Anthony T. Murphy, Derrick R. Witcher, Igor Theurl, Günter Weiss

https://doi.org/10.3324/haematol.2013.099481

Health-related quality of life in children with newly diagnosed immune thrombocytopenia

Katja M.J. Heitink-Pollé, Lotte Haverman, Kim V. Annink, Sarah J. Schep, Masja de Haas, Marrie C.A. Bruin

https://doi.org/10.3324/haematol.2014.106963

Errata Corrige

Molecular analysis of Fanconi anemia: the experience of the Bone Marrow Failure Study Group of the Italian Association of Pediatric Onco-Hematology

Daniela De Rocco, Roberta Bottega, Enrico Cappelli, Simona Cavani, Maria Criscuolo, Elena Nicchia, Fabio Corsolini, Chiara Greco, Adriana Borriello, Johanna Svahn, Marta Pillon, Cristina Mecucci, Gabriella Casazza, Federico Verzegnassi, Chiara Cugno, Anna Locasciulli, Piero Farruggia, Daniela Longoni, Ugo Ramenghi, Walter Barberi, Fabio Tucci, Silverio Perrotta, Paola Grammatico, Helmut Hanenberg, Fulvio Della Ragione, Carlo Dufour, Anna Savoia

https://doi.org/10.3324/haematol.2014.116004

Online Only Articles

PDGFRB-rearranged T-lymphoblastic leukemia/lymphoma occurring with myeloid neoplasms: the missing link supporting a stem cell origin

Sarah L. Ondrejka, Armin G. Jegalian, Annette S. Kim, Devon S. Chabot-Richards, Jennifer Giltnane, David R. Czuchlewski, Shashirekha Shetty, Mikkael A Sekeres, Ashwini Yenamandra, David Head, Madan Jagasia, Eric D. Hsi

https://doi.org/10.3324/haematol.2014.105452

SETBP1 mutations in 106 patients with therapy-related myeloid neoplasms

Emiliano Fabiani, Giulia Falconi, Luana Fianchi, Marianna Criscuolo, Giuseppe Leone, Maria Teresa Voso

https://doi.org/10.3324/haematol.2014.108159

Gamma heavy chain disease lacks the MYD88 L265p mutation associated with lymphoplasmacytic lymphoma

Fatima Hamadeh, Stephen MacNamara, Chris M Bacon, Aliyah R. Sohani, Steven H. Swerdlow, James R. Cook

https://doi.org/10.3324/haematol.2014.108688

Bendamustine and subcutaneous alemtuzumab combination is an effective treatment in relapsed/refractory chronic lymphocytic leukemia patients

Marco Montillo, Alessandra Tedeschi, Gianluca Gaidano, Marta Coscia, Valeria Belsito Petrizzi, Ester Orlandi, Nicola Cascavilla, Paolo Ghia, Marina Motta, Andrea Gallamini, Anna Maria Frustaci, Davide Rossi, Lorenzo De Paoli, Michele Nichelatti, Enrica Morra, Massimo Massaia

https://doi.org/10.3324/haematol.2014.106740

Carfilzomib, lenalidomide, and low-dose dexamethasone in elderly patients with newly diagnosed multiple myeloma

Dominik Dytfeld, Jagoda Jasielec, Kent A. Griffith, Daniel Lebovic, David H. Vesole, Sundar Jagannath, Ammar Al-Zoubi, Tara Anderson, Kristen Detweiler-Short, Keith Stockerl-Goldstein, Asra Ahmed, Terri Jobkar, Diane E. Durecki, Kathryn McDonnell, Melissa Mietzel, Daniel Couriel, Mark Kaminski, Ravi Vij, Andrzej J. Jakubowiak

https://doi.org/10.3324/haematol.2014.110395

Genetic characterization of acquired aplastic anemia by targeted sequencing

Michael Heuser, Carola Schlarmann, Vera Dobbernack, Victoria Panagiota, Lutz Wiehlmann, Carolin Walter, Fabian Beier, Patrick Ziegler, Haiyang Yun, Sofia Kade, Aylin Kirchner, Liu Huang, Christian Koenecke, Matthias Eder, Tim H. Brümmendorf, Martin Dugas, Arnold Ganser, Felicitas Thol

https://doi.org/10.3324/haematol.2013.101642

Severe nondominant hereditary spherocytosis due to uniparental isodisomy at the SPTA1 locus

Hannah Bogardus, Vincent P. Schulz, Yelena Maksimova, Barbara A. Miller, Peining Li, Bernard G. Forget, Patrick G. Gallagher

https://doi.org/10.3324/haematol.2014.110312

Hematologic parameters predicting a response to oral iron therapy in chronic inflammation

Susanne van Santen, Quirijn de Mast, Janine D. Oosting, Annelies van Ede, Dorine W. Swinkels, André J.A.M. van der Ven

https://doi.org/10.3324/haematol.2014.106799