October, 2013
No. 98 (10)

Editorials

Pathogen safety of long-term treatments for bleeding disorders: still relevant to current practice

Giovanni Di Minno, Mariana Canaro, James W. Ironside, David Navarro, Carlo Federico Perno, Andreas Tiede, Lutz Gürtler

https://doi.org/10.3324/haematol.2013.084145

Review Articles

Advances in myelofibrosis: a clinical case approach

John O. Mascarenhas, Attilio Orazi, Kapil N. Bhalla, Richard E. Champlin, Claire Harrison, Ronald Hoffman

https://doi.org/10.3324/haematol.2013.086348

Articles

Chronic Myeloid Leukemia

The BCR-ABLT315I mutation compromises survival in chronic phase chronic myelogenous leukemia patients resistant to tyrosine kinase inhibitors, in a matched pair analysis

Franck E. Nicolini, Amr R. Ibrahim, Simona Soverini, Giovanni Martinelli, Martin C. Müller, Andreas Hochhaus, Inge H. Dufva, Dong-Wook Kim, Jorge Cortes, Michael J. Mauro, Charles Chuah, Hélène Labussière, Stéphane Morisset, Catherine Roche-Lestienne, Eric Lippert, Sandrine Hayette, Senaka Peter, Wei Zhou, Véronique Maguer-Satta, Mauricette Michallet, John Goldman, Jane F. Apperley, François-Xavier Mahon, David Marin, Gabriel Etienne

https://doi.org/10.3324/haematol.2012.080234

Chronic Myeloproliferative Disorders

Increased reactive oxygen species production and p47phox phosphorylation in neutrophils from myeloproliferative disorders patients with JAK2 (V617F) mutation

Margarita Hurtado-Nedelec, Marie-José Csillag-Grange, Tarek Boussetta, Sahra Amel Belambri, Michèle Fay, Bruno Cassinat, Marie-Anne Gougerot-Pocidalo, Pham My-Chan Dang, Jamel El-Benna

https://doi.org/10.3324/haematol.2012.082560

Acute Myeloid Leukemia

Prognosis of patients with core binding factor acute myeloid leukemia after first relapse

Saiko Kurosawa, Shuichi Miyawaki, Takuhiro Yamaguchi, Heiwa Kanamori, Toru Sakura, Yukiyoshi Moriuchi, Fumiaki Sano, Takeshi Kobayashi, Atsushi Yasumoto, Kazuo Hatanaka, Masamitsu Yanada, Yuichiro Nawa, Jin Takeuchi, Yukinori Nakamura, Shin Fujisawa, Hirohiko Shibayama, Ikuo Miura, Takahiro Fukuda

https://doi.org/10.3324/haematol.2012.078030

A single center analysis of nucleophosmin in acute myeloid leukemia: value of combining immunohistochemistry with molecular mutation analysis

Carolien M. Woolthuis, André B. Mulder, Rikst Nynke Verkaik-Schakel, Stefano Rosati, Arjan Diepstra, Eva van den Berg, Jan Jacob Schuringa, Edo Vellenga, Philip M. Kluin, Gerwin Huls

https://doi.org/10.3324/haematol.2012.079806

Acute Lymphoblastic Leukemia

Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells

Stefanie A. Hartsink-Segers, Carla Exalto, Matthew Allen, Daniel Williamson, Steven C. Clifford, Martin Horstmann, Huib N. Caron, Rob Pieters, Monique L. Den Boer

https://doi.org/10.3324/haematol.2013.084434

Non-Hodgkin’s Lymphoma

MYC protein expression and genetic alterations have prognostic impact in patients with diffuse large B-cell lymphoma treated with immunochemotherapy

Alexandra Valera, Armando López-Guillermo, Teresa Cardesa-Salzmann, Fina Climent, Eva González-Barca, Santiago Mercadal, Íñigo Espinosa, Silvana Novelli, Javier Briones, José L. Mate, Olga Salamero, Juan M. Sancho, Leonor Arenillas, Sergi Serrano, Nadina Erill, Daniel Martínez, Paola Castillo, Jordina Rovira, Antonio Martínez, Elias Campo, Luis Colomo

https://doi.org/10.3324/haematol.2013.086173

First-line treatment with rituximab-hyperCVAD alternating with rituximab-methotrexate-cytarabine and followed by consolidation with 90Y-ibritumomab-tiuxetan in patients with mantle cell lymphoma. Results of a multicenter, phase 2 pilot trial from the GELTAMO group

Reyes Arranz, Ana García-Noblejas, Carlos Grande, Jimena Cannata-Ortiz, José J. Sánchez, José-Antonio García-Marco, Concepción Aláez, Javier Pérez-Calvo, Pilar Martínez-Sánchez, Blanca Sánchez-González, Miguel-Angel Canales, Eulogio Conde, Alejandro Martín, Eva Arranz, María-José Terol, Antonio Salar, Dolores Caballero

https://doi.org/10.3324/haematol.2013.088377


Multiple Myeloma

Amyloidosis

Stem Cell Transplantation

Cell Therapy and Immunotherapy

Clonal analysis of multipotent stromal cells derived from CD271+ bone marrow mononuclear cells: functional heterogeneity and different mechanisms of allosuppression

Zyrafete Kuçi, Julia Seiberth, Hatixhe Latifi-Pupovci, Sibylle Wehner, Stefan Stein, Manuel Grez, Halvard Bönig, Ulrike Köhl, Thomas Klingebiel, Peter Bader, Selim Kuçi

https://doi.org/10.3324/haematol.2013.092700

Common variable immunodeficiency and idiopathic primary hypogammaglobulinemia: two different conditions within the same disease spectrum

Gertjan J. Driessen, Virgil A.S.H. Dalm, P. Martin van Hagen, H. Anne Grashoff, Nico G. Hartwig, Annemarie M. C. van Rossum, Adilia Warris, Esther de Vries, Barbara H. Barendregt, Ingrid Pico, Sandra Posthumus, Menno C. van Zelm, Jacques J.M. van Dongen, Mirjam van der Burg

https://doi.org/10.3324/haematol.2013.085076

Erythropoiesis & Its Disorders

Congenital erythrocytosis associated with gain-of-function HIF2A gene mutations and erythropoietin levels in the normal range

Silverio Perrotta, Daniel P. Stiehl, Francesca Punzo, Saverio Scianguetta, Adriana Borriello, Debora Bencivenga, Maddalena Casale, Bruno Nobili, Silvia Fasoli, Adriana Balduzzi, Lilla Cro, Katarzyna J. Nytko, Roland H. Wenger, Fulvio Della Ragione

https://doi.org/10.3324/haematol.2013.088369

Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with age

Bryan J. McCranor, Jacqueline M. Langdon, Olivier D. Prince, Laurette K. Femnou, Alan E. Berger, Chris Cheadle, Curt I. Civin, Airie Kim, Seth Rivera, Tomas Ganz, Sophie Vaulont, Qian-Li Xue, Jeremy D. Walston, Cindy N. Roy

https://doi.org/10.3324/haematol.2013.087114

Heterozygosity for the Y701C STAT1 mutation in a multiplex kindred with multifocal osteomyelitis

Osamu Hirata, Satoshi Okada, Miyuki Tsumura, Reiko Kagawa, Mizuka Miki, Hiroshi Kawaguchi, Kazuhiro Nakamura, Stéphanie Boisson-Dupuis, Jean-Laurent Casanova, Yoshihiro Takihara, Masao Kobayashi

https://doi.org/10.3324/haematol.2013.083741

Disorders of Coagulation

Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter

Yohann Repessé, Ivan Peyron, Jordan D Dimitrov, Suryasarathi Dasgupta, Elika Farrokhi Moshai, Catherine Costa, Annie Borel-Derlon, Benoit Guillet, Roseline D’Oiron, Achille Aouba, Chantal Rothschild, Johannes Oldenburg, Anna Pavlova, Srinivas V Kaveri, Sébastien Lacroix-Desmazes

https://doi.org/10.3324/haematol.2013.084665

Online Only Articles

Mechanism of impaired glucose metabolism during nilotinib therapy in patients with chronic myelogenous leukemia

Zdenek Racil, Filip Razga, Jana Drapalova, Lucie Buresova, Daniela Zackova, Martina Palackova, Lukas Semerad, Ludmila Malaskova, Martin Haluzik, Jiri Mayer

https://doi.org/10.3324/haematol.2013.086355

Combined antifungal approach for the treatment of invasive mucormycosis in patients with hematologic diseases: a report from the SEIFEM and FUNGISCOPE registries

Livio Pagano, Oliver A. Cornely, Alessandro Busca, Morena Caira, Simone Cesaro, Cristiana Gasbarrino, Corrado Girmenia, Werner J. Heinz, Raoul Herbrecht, Cornelia Lass-Flörl, Annamaria Nosari, Leonardo Potenza, Zdenek Racil, Volker Rickerts, Donald C. Sheppard, Arne Simon, Andrew J. Ullmann, Caterina Giovanna Valentini, Jörg Janne Vehreschild, Anna Candoni, Maria J.G.T. Vehreschild

https://doi.org/10.3324/haematol.2012.083063