December, 2012
No. 97 (12)

Editorials

H-Net, the European Network for Harmonization of Training in Hematology, and its policy

Thom Duyvené de Wit, Eva Hellström-Lindberg, Ulrich Jäger, Gareth Evans-Jones, Carin Smand

https://doi.org/10.3324/haematol.2012.078964

Review Articles

Articles

Human induced pluripotent stem cells can reach complete terminal maturation: in vivo and in vitro evidence in the erythropoietic differentiation model

Ladan Kobari, Frank Yates, Noufissa Oudrhiri, Alain Francina, Laurent Kiger, Christelle Mazurier, Shaghayegh Rouzbeh, Wassim El-Nemer, Nicolas Hebert, Marie-Catherine Giarratana, Sabine François, Alain Chapel, Hélène Lapillonne, Dominique Luton, Annelise Bennaceur-Griscelli, Luc Douay

https://doi.org/10.3324/haematol.2011.055566

Genetic variations in T-cell activation and effector pathways modulate alloimmune responses after allogeneic hematopoietic stem cell transplantation in patients with hematologic malignancies

Haowen Xiao, Yi Luo, Xiaoyu Lai, Shan Fu, Jimin Shi, Yamin Tan, Jingsong He, Wanzhuo Xie, Weiyan Zheng, Li-Mengmeng Wang, Lifei Zhang, Lizhen Liu, Xiujin Ye, Xiaohong Yu, Zhen Cai, Maofang Lin, He Huang

https://doi.org/10.3324/haematol.2012.066159

CYBRD1 as a modifier gene that modulates iron phenotype in HFE p.C282Y homozygous patients

Sara Pelucchi, Raffaella Mariani, Stefano Calza, Anna Ludovica Fracanzani, Giulia Litta Modignani, Francesca Bertola, Fabiana Busti, Paola Trombini, Mirella Fraquelli, Gian Luca Forni, Domenico Girelli, Silvia Fargion, Claudia Specchia, Alberto Piperno

https://doi.org/10.3324/haematol.2012.062661

Metalloreductase Steap3 coordinates the regulation of iron homeostasis and inflammatory responses

Fan Zhang, Yunlong Tao, Zhuzhen Zhang, Xin Guo, Peng An, Yuanyuan Shen, Qian Wu, Yu Yu, Fudi Wang

https://doi.org/10.3324/haematol.2012.063974

Partial tolerance of autoreactive B and T cells to erythrocyte-specific self-antigens in mice

Krystalyn E. Hudson, Jeanne E. Hendrickson, Chantel M. Cadwell, Neal N. Iwakoshi, James C. Zimring

https://doi.org/10.3324/haematol.2012.065144

Effects of switching from a reduced dose imiglucerase to velaglucerase in type 1 Gaucher disease: clinical and biochemical outcomes

Laura van Dussen, Timothy M. Cox, Erik J. Hendriks, Elizabeth Morris, Erik M. Akkerman, Mario Maas, Johanna E. M. Groener, Johannes M.F.G. Aerts, Patrick B. Deegan, Carla E. M. Hollak

https://doi.org/10.3324/haematol.2011.059071

Hemostasis

Leukocyte- and endothelial-derived microparticles: a circulating source for fibrinolysis

Romaric Lacroix, Laurent Plawinski, Stéphane Robert, Loïc Doeuvre, Florence Sabatier, Sara Martinez de Lizarrondo, Anna Mezzapesa, Francine Anfosso, Aurelie S. Leroyer, Pascale Poullin, Noémie Jourde, Makon-Sébastien Njock, Chantal M. Boulanger, Eduardo Anglés-Cano, Françoise Dignat-George

https://doi.org/10.3324/haematol.2012.066167

Improved platelet survival after cold storage by prevention of glycoprotein Ibα clustering in lipid rafts

Eelo Gitz, Cornelis A Koekman, Dave J. van den Heuvel, Hans Deckmyn, Jan W. Akkerman, Hans C. Gerritsen, Rolf T. Urbanus

https://doi.org/10.3324/haematol.2012.066290

A randomized phase II study to evaluate tacrolimus in combination with sirolimus or methotrexate after allogeneic hematopoietic cell transplantation

Joseph Pidala, Jongphil Kim, Heather Jim, Mohamed A. Kharfan-Dabaja, Taiga Nishihori, Hugo F. Fernandez, Marcie Tomblyn, Lia Perez, Janelle Perkins, Mian Xu, William E. Janssen, Anandaraman Veerapathran, Brian C. Betts, Frederick L. Locke, Ernesto Ayala, Teresa Field, Leonel Ochoa, Melissa Alsina, Claudio Anasetti

https://doi.org/10.3324/haematol.2012.067140

Chronic Myeloproliferative Disorders

Use of CBL exon 8 and 9 mutations in diagnosis of myeloproliferative neoplasms and myelodysplastic/myeloproliferative disorders: an analysis of 636 cases

Susanne Schnittger, Ulrike Bacher, Tamara Alpermann, Andreas Reiter, Madlen Ulke, Frank Dicker, Christiane Eder, Alexander Kohlmann, Vera Grossmann, Andreas Kowarsch, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach

https://doi.org/10.3324/haematol.2012.065375

Remission maintenance in acute myeloid leukemia: impact of functional histamine H2 receptors expressed by leukemic cells

Johan Aurelius, Anna Martner, Mats Brune, Lars Palmqvist, Markus Hansson, Kristoffer Hellstrand, Fredrik B. Thoren

https://doi.org/10.3324/haematol.2012.066399

RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes

Philipp A. Greif, Nikola P. Konstandin, Klaus H. Metzeler, Tobias Herold, Zlatana Pasalic, Bianka Ksienzyk, Annika Dufour, Friederike Schneider, Stephanie Schneider, Purvi M. Kakadia, Jan Braess, Maria Cristina Sauerland, Wolfgang E. Berdel, Thomas Büchner, Bernhard J. Woermann, Wolfgang Hiddemann, Karsten Spiekermann, Stefan K. Bohlander

https://doi.org/10.3324/haematol.2012.064667

Updated survival analysis of a randomized phase III study of subcutaneous versus intravenous bortezomib in patients with relapsed multiple myeloma

Bertrand Arnulf, Halyna Pylypenko, Sebastian Grosicki, Ievgenii Karamanesht, Xavier Leleu, Helgi van de Velde, Huaibao Feng, Andrew Cakana, William Deraedt, Philippe Moreau

https://doi.org/10.3324/haematol.2012.067793

Letters to the Editor

Transfusion independence and survival in patients with acute myeloid leukemia treated with 5-azacytidine

Mathilde Gavillet, Jasmine Noetzli, Sabine Blum, Michel A. Duchosal, Olivier Spertini, Jean-Francois Lambert

https://doi.org/10.3324/haematol.2012.065151

Clonal patterns of X-chromosome inactivation in peripheral blood cells of female patients with chronic idiopathic neutropenia

Semeli Mastrodemou, Vasilios Vazgiourakis, Maria Velegraki, Konstantia Pavlaki, George N. Goulielmos, Helen A. Papadaki

https://doi.org/10.3324/haematol.2012.069310

Mutations inDNMT3A and loss of RKIP are independent events in acute monocytic leukemia

Isabella Fried, Albert Wölfler, Franz Quehenberger, Gerald Hoefler, Heinz Sill, Armin Zebisch

https://doi.org/10.3324/haematol.2012.068429

Online Only Articles

Flow cytometry test for hereditary spherocytosis

Géraud Mackiewicz, François Bailly, Bernardine Favre, Julien Guy, Marc Maynadié, François Girodon

https://doi.org/10.3324/haematol.2012.072660

Testing for hereditary spherocytosis: a French experience

Caroline Mayeur-Rousse, Mélanie Gentil, Jérémie Botton, Madeleine Fénéant Thibaut, Corinne Guitton, Véronique Picard

https://doi.org/10.3324/haematol.2012.074070

Hematology News

Original Articles and Brief Reports

Erythropoiesis & Its Disorders

High frequency of ribosomal protein gene deletions in Italian Diamond-Blackfan anemia patients detected by multiplex ligation-dependent probe amplification assay

Paola Quarello, Emanuela Garelli, Alfredo Brusco, Adriana Carando, Cecilia Mancini, Patrizia Pappi, Luciana Vinti, Johanna Svahn, Irma Dianzani, Ugo Ramenghi

https://doi.org/10.3324/haematol.2012.062281

Favorable outcome of patients who have 13q deletion: a suggestion for revision of the WHO ‘MDS-U’ designation

Kohei Hosokawa, Takamasa Katagiri, Naomi Sugimori, Ken Ishiyama, Yumi Sasaki, Yu Seiki, Aiko Sato-Otsubo, Masashi Sanada, Seishi Ogawa, Shinji Nakao

https://doi.org/10.3324/haematol.2011.061127

Factor VIII and von Willebrand factor are ligands for the carbohydrate-receptor Siglec-5

Julie N. Pegon, Mohamad Kurdi, Caterina Casari, Soline Odouard, Cécile V. Denis, Olivier D. Christophe, Peter J. Lenting

https://doi.org/10.3324/haematol.2012.063297