October, 2011
No. 96 (10)

Editorials

Review Articles

Articles

Multiple oligomerization domains of KANK1-PDGFRβ are required for JAK2-independent hematopoietic cell proliferation and signaling via STAT5 and ERK

Sandrine Medves, Laura A. Noël, Carmen P. Montano-Almendras, Roxana I. Albu, Hélène Schoemans, Stefan N. Constantinescu, Jean-Baptiste Demoulin

https://doi.org/10.3324/haematol.2011.040147

Iron Metabolism & Its Disorders

Over-expression of mitochondrial ferritin affects the JAK2/STAT5 pathway in K562 cells and causes mitochondrial iron accumulation

Paolo Santambrogio, Benedetta Gaia Erba, Alessandro Campanella, Anna Cozzi, Vincenza Causarano, Laura Cremonesi, Anna Gallì, Matteo Giovanni Della Porta, Rosangela Invernizzi, Sonia Levi

https://doi.org/10.3324/haematol.2011.042952

Impact of the degree of anemia on the outcome of patients with myelodysplastic syndrome and its integration into the WHO classification-based Prognostic Scoring System (WPSS)

Luca Malcovati, Matteo G. Della Porta, Corinna Strupp, Ilaria Ambaglio, Andrea Kuendgen, Kathrin Nachtkamp, Erica Travaglino, Rosangela Invernizzi, Cristiana Pascutto, Mario Lazzarino, Ulrich Germing, Mario Cazzola

https://doi.org/10.3324/haematol.2011.044602

A prospective multicenter observational study of decitabine treatment in Korean patients with myelodysplastic syndrome

Je-Hwan Lee, Jun Ho Jang, Jinny Park, Seonyang Park, Young-Don Joo, Yeo-Kyeoung Kim, Hoon-Gu Kim, Chul Won Choi, Sung-Hyun Kim, Seong Kyu Park, Eunkyung Park, Yoo Hong Min

https://doi.org/10.3324/haematol.2011.046078

Down-regulation of EVI1 is associated with epigenetic alterations and good prognosis in patients with acute myeloid leukemia

Iria Vázquez, Miren Maicas, José Cervera, Xabier Agirre, Oskar Marin-Béjar, Nerea Marcotegui, Carmen Vicente, Idoya Lahortiga, Maria Gomez-Benito, Claudia Carranza, Ana Valencia, Salut Brunet, Eva Lumbreras, Felipe Prosper, María T. Gómez-Casares, Jesús M. Hernández-Rivas, María J. Calasanz, Miguel A. Sanz, Jorge Sierra, María D. Odero

https://doi.org/10.3324/haematol.2011.040535

Charlson comorbidity index and adult comorbidity evaluation-27 scores might predict treatment compliance and development of pleural effusions in elderly patients with chronic myeloid leukemia treated with second-line dasatinib

Massimo Breccia, Roberto Latagliata, Fabio Stagno, Luigiana Luciano, Antonella Gozzini, Fausto Castagnetti, Carmen Fava, Francesco Cavazzini, Mario Annunziata, Antonella Russo Rossi, Patrizia Pregno, Elisabetta Abruzzese, Paolo Vigneri, Giovanna Rege-Cambrin, Simona Sica, Fabrizio Pane, Valeria Santini, Giorgina Specchia, Gianantonio Rosti, Giuliana Alimena

https://doi.org/10.3324/haematol.2011.041251

Prognostic value of FLT3 mutations in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline monochemotherapy

Eva Barragán, Pau Montesinos, Mireia Camos, Marcos González, Maria J. Calasanz, José Román-Gómez, Maria T. Gómez-Casares, Rosa Ayala, Javier López, Óscar Fuster, Dolors Colomer, Carmen Chillón, María J. Larrayoz, Pedro Sánchez-Godoy, José González-Campos, Félix Manso, Maria L. Amador, Edo Vellenga, Bob Lowenberg, Miguel A. Sanz

https://doi.org/10.3324/haematol.2011.044933

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia

Brian V. Balgobind, Iris H.I.M. Hollink, Susan T.C.J.M. Arentsen-Peters, Martin Zimmermann, Jochen Harbott, H. Berna Beverloo, Anne R.M. von Bergh, Jacqueline Cloos, Gertjan J.L. Kaspers, Valerie de Haas, Zuzana Zemanova, Jan Stary, Jean-Michel Cayuela, Andre Baruchel, Ursula Creutzig, Dirk Reinhardt, Rob Pieters, C. Michel Zwaan, Marry M. van den Heuvel-Eibrink

https://doi.org/10.3324/haematol.2010.038976

Acute Myeloid Leukemia

Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

Heiko Becker, Kati Maharry, Michael D. Radmacher, Krzysztof Mrózek, Klaus H. Metzeler, Susan P. Whitman, Sebastian Schwind, Jessica Kohlschmidt, Yue-Zhong Wu, Bayard L. Powell, Thomas H. Carter, Jonathan E. Kolitz, Meir Wetzler, Andrew J. Carroll, Maria R. Baer, Joseph O. Moore, Michael A. Caligiuri, Richard A. Larson, Guido Marcucci, Clara D. Bloomfield

https://doi.org/10.3324/haematol.2011.041905

Association between single nucleotide polymorphism-genotype and outcome of patients with chronic lymphocytic leukemia in a randomized chemotherapy trial

Rachel Wade, Maria Chiara Di Bernardo, Sue Richards, Davide Rossi, Dalemari Crowther-Swanepoel, Gianluca Gaidano, David G. Oscier, Daniel Catovsky, Richard S. Houlston

https://doi.org/10.3324/haematol.2011.043471

Impact of genetic abnormalities after allogeneic stem cell transplantation in multiple myeloma: a report of the Société Française de Greffe de Moelle et de Thérapie Cellulaire

Damien Roos-Weil, Philippe Moreau, Hervé Avet-Loiseau, Jean-Louis Golmard, Mathieu Kuentz, Stéphane Vigouroux, Gérard Socié, Sabine Furst, Jean Soulier, Steven Le Gouill, Sylvie François, Anne Thiebaut, Agnès Buzyn, Natacha Maillard, Ibrahim Yakoub-Agha, Nicole Raus, Jean-Paul Fermand, Mauricette Michallet, Didier Blaise, Nathalie Dhédin

https://doi.org/10.3324/haematol.2011.042713

Surface molecule CD229 as a novel target for the diagnosis and treatment of multiple myeloma

Djordje Atanackovic, Jens Panse, York Hildebrandt, Adam Jadczak, Sebastian Kobold, Yanran Cao, Julia Templin, Sabrina Meyer, Henrike Reinhard, Katrin Bartels, Nesrine Lajmi, Axel R. Zander, Andreas H. Marx, Carsten Bokemeyer, Nicolaus Kröger

https://doi.org/10.3324/haematol.2010.036814

High CD33 expression levels in acute myeloid leukemia cells carrying the nucleophosmin (NPM1) mutation

Maria Stefania De Propris, Sara Raponi, Daniela Diverio, Maria Laura Milani, Giovanna Meloni, Brunangelo Falini, Robin Foà, Anna Guarini

https://doi.org/10.3324/haematol.2011.043786

The levels of IL-17A and of the cytokines involved in Th17 cell commitment are increased in patients with chronic immune thrombocytopenia

Andreia Maria Camargos Rocha, Cláudia Souza, Gifone Aguiar Rocha, Fabrício Freire de Melo, Nelma Cristina Diogo Clementino, Marília Campos Abreu Marino, Adriana Bozzi, Maria Luiza Silva, Olindo Assis Martins Filho, Dulciene Maria Magalhães Queiroz

https://doi.org/10.3324/haematol.2011.046417

Letters to the Editor

Acute Promyelocytic Leukemia

FIP1L1/RARA with breakpoint at FIP1L1 intron 13: a variant translocation in acute promyelocytic leukemia

Juliane Menezes, Francesco Acquadro, Concepción Perez-Pons de la Villa, Félix García-Sánchez, Sara Álvarez, Juan C. Cigudosa

https://doi.org/10.3324/haematol.2011.047134

Disorders of Hemostasis

An unexpected transmission of von Willebrand disease type 3: the first case of maternal uniparental disomy 12

Pierre Boisseau, Mathilde Giraud, Catherine Ternisien, Agnès Veyradier, Edith Fressinaud, Armelle Lefrancois, Stéphane Bezieau, Marc Fouassier

https://doi.org/10.3324/haematol.2010.036897

Acute Myeloid Leukemia

Minimal residual disease-directed preemptive treatment with azacitidine in patients with NPM1-mutant acute myeloid leukemia and molecular relapse

Katja Sockel, Martin Wermke, Jörgen Radke, Alexander Kiani, Markus Schaich, Martin Bornhäuser, Gerhard Ehninger, Christian Thiede, Uwe Platzbecker

https://doi.org/10.3324/haematol.2011.044388

Online Only Articles

Brief Reports

18F-FDG-PET/CT for detection of extramedullary acute myeloid leukemia

Friedrich Stölzel, Christoph Röllig, Jörgen Radke, Brigitte Mohr, Uwe Platzbecker, Martin Bornhäuser, Tobias Paulus, Gerhard Ehninger, Klaus Zoephel, Markus Schaich

https://doi.org/10.3324/haematol.2011.045047

CYP2C8 gene polymorphism and bisphosphonate-related osteonecrosis of the jaw in patients with multiple myeloma

Esperanza Such, José Cervera, Evangelos Terpos, José V Bagán, Amparo Avaria, Inés Gómez, María Margaix, Mariam Ibañez, Irene Luna, Lourdes Cordón, Mónica Roig, Miguel A. Sanz, Meletios A. Dimopoulos, Javier de la Rubia

https://doi.org/10.3324/haematol.2011.042572