March, 2010
No. 95 (3)

Editorials

Articles

Rho GTPase Cdc42 is essential for human T-cell development

Kaatje Smits, Veronica Iannucci, Veronique Stove, Peter Van Hauwe, Evelien Naessens, Pieter J. Meuwissen, Kevin K. Ariën, Mostafa Bentahir, Jean Plum, Bruno Verhasselt

https://doi.org/10.3324/haematol.2009.006890

Pregnancy and β-thalassemia: an Italian multicenter experience

Raffaella Origa, Antonio Piga, Giovanni Quarta, Gian Luca Forni, Filomena Longo, Angela Melpignano, Renzo Galanello

https://doi.org/10.3324/haematol.2009.012393

Long-term follow-up of patients with moderate aplastic anemia and pure red cell aplasia treated with daclizumab

Elaine M. Sloand, Matthew J. Olnes, Barbara Weinstein, Colin Wu, Jaroslaw Maciejewski, Phillip Scheinberg, Neal S. Young

https://doi.org/10.3324/haematol.2009.013557

Unimpaired terminal erythroid differentiation and preserved enucleation capacity in myelodysplastic 5q(del) clones: a single cell study

Laurent Garderet, Ladan Kobari, Christelle Mazurier, Caroline De Witte, Marie-Catherine Giarratana, Christine Pérot, Norbert Claude Gorin, Hélène Lapillonne, Luc Douay

https://doi.org/10.3324/haematol.2009.012773

Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion

Maria Ximeri, Athanasios Galanopoulos, Mirjam Klaus, Agapi Parcharidou, Krinio Giannikou, Maria Psyllaki, Argyrios Symeonidis, Vasiliki Pappa, Zafiris Kartasis, Dimitra Liapi, Eleftheria Hatzimichael, Styliani Kokoris, Penelope Korkolopoulou, Constantina Sambani, Charalampos Pontikoglou, Helen A. Papadaki

https://doi.org/10.3324/haematol.2009.010876

Autocrine IGF-1/IGF-1R signaling is responsible for constitutive PI3K/Akt activation in acute myeloid leukemia: therapeutic value of neutralizing anti-IGF-1R antibody

Nicolas Chapuis, Jérôme Tamburini, Pascale Cornillet-Lefebvre, Lucile Gillot, Valérie Bardet, Lise Willems, Sophie Park, Alexa S Green, Norbert Ifrah, François Dreyfus, Patrick Mayeux, Catherine Lacombe, Didier Bouscary

https://doi.org/10.3324/haematol.2009.010785

Additional chromosome abnormalities in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy

José Cervera, Pau Montesinos, Jesús M. Hernández-Rivas, María J. Calasanz, Anna Aventín, María T. Ferro, Elisa Luño, Javier Sánchez, Edo Vellenga, Chelo Rayón, Gustavo Milone, Javier de la Serna, Concha Rivas, José D. González, Mar Tormo, Elena Amutio, Marcos González, Salut Brunet, Bob Lowenberg, Miguel A. Sanz

https://doi.org/10.3324/haematol.2009.013243

The inducible T-cell co-stimulator molecule is expressed on subsets of T cells and is a new marker of lymphomas of T follicular helper cell-derivation

Teresa Marafioti, Jennifer C. Paterson, Erica Ballabio, Andreas Chott, Yasodha Natkunam, Manuel Rodriguez-Justo, Anne Plonquet, Socorro M. Rodriguez-Pinilla, Wolfram Klapper, Martin-L. Hansmann, Stefano A. Pileri, Peter G. Isaacson, Harald Stein, Miguel A. Piris, David Y. Mason, Philippe Gaulard

https://doi.org/10.3324/haematol.2009.010991

T-cell/histiocyte-rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response

Peter Van Loo, Thomas Tousseyn, Vera Vanhentenrijk, Daan Dierickx, Agnieszka Malecka, Isabelle Vanden Bempt, Gregor Verhoef, Jan Delabie, Peter Marynen, Patrick Matthys, Chris De Wolf-Peeters

https://doi.org/10.3324/haematol.2009.009647

Thalidomide decreases gelatinase production by malignant B lymphoid cell lines through disruption of multiple integrin-mediated signaling pathways

Marta Segarra, Ester Lozano, Marc Corbera-Bellalta, Carme Vilardell, Maria-Teresa Cibeira, Jordi Esparza, Nora Izco, Joan Bladé, Maria C. Cid

https://doi.org/10.3324/haematol.2009.006395

The utility of a prognostic index for predicting time to first treatment in early chronic lymphocytic leukemia: the GIMEMA experience

Stefano Molica, Francesca R. Mauro, Vincenzo Callea, Diana Giannarelli, Francesco Lauria, Bruno Rotoli, Agostino Cortelezzi, Vincenzo Liso, Robin Foà

https://doi.org/10.3324/haematol.2009.011767

IgA and IgG hypogammaglobulinemia in Waldenström’s macroglobulinemia

Zachary R. Hunter, Robert J. Manning, Christine Hanzis, Bryan T. Ciccarelli, Leukothea Ioakimidis, Christopher J. Patterson, Megan C. Lewicki, Hsuiyi Tseng, Ping Gong, Xia Liu, Yangsheng Zhou, Guang Yang, Jenny Sun, Lian Xu, Patricia Sheehy, Massimo Morra, Steven P. Treon

https://doi.org/10.3324/haematol.2009.010348

Prognostic impact of pre-transplantation transfusion history and secondary iron overload in patients with myelodysplastic syndrome undergoing allogeneic stem cell transplantation: a GITMO study

Emilio Paolo Alessandrino, Matteo Giovanni Della Porta, Andrea Bacigalupo, Luca Malcovati, Emanuele Angelucci, Maria Teresa Van Lint, Michele Falda, Francesco Onida, Massimo Bernardi, Stefano Guidi, Barbarella Lucarelli, Alessandro Rambaldi, Raffaella Cerretti, Paola Marenco, Pietro Pioltelli, Cristiana Pascutto, Rosi Oneto, Laura Pirolini, Renato Fanin, Alberto Bosi

https://doi.org/10.3324/haematol.2009.011429

Class II-associated invariant chain peptide down-modulation enhances the immunogenicity of myeloid leukemic blasts resulting in increased CD4+ T-cell responses

Marvin M. van Luijn, Martine E.D. Chamuleau, James A. Thompson, Suzanne Ostrand-Rosenberg, Theresia M. Westers, Yuri Souwer, Gert J. Ossenkoppele, S. Marieke van Ham, Arjan A. van de Loosdrecht

https://doi.org/10.3324/haematol.2009.010595

Combined modality treatment improves tumor control and overall survival in patients with early stage Hodgkin’s lymphoma: a systematic review

Christine Herbst, Fareed A. Rehan, Corinne Brillant, Julia Bohlius, Nicole Skoetz, Holger Schulz, Ina Monsef, Lena Specht, Andreas Engert

https://doi.org/10.3324/haematol.2009.015644

Hepcidin targets ferroportin for degradation in hepatocytes

Guillemette Ramey, Jean-Christophe Deschemin, Béatrice Durel, François Canonne-Hergaux, Gaël Nicolas, Sophie Vaulont

https://doi.org/10.3324/haematol.2009.014399

ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions

Katrien Van Roosbroeck, Jan Cools, Daan Dierickx, José Thomas, Peter Vandenberghe, Michel Stul, Jan Delabie, Chris De Wolf-Peeters, Peter Marynen, Iwona Wlodarska

https://doi.org/10.3324/haematol.2009.014761

Letters to the Editor


Amyloidosis

Disorders of Hemostasis

Successful eradication of acquired factor-VIII-inhibitor using single low-dose rituximab

Martin Wermke, Malte von Bonin, Siegmund Gehrisch, Gabriele Siegert, Gerhard Ehninger, Uwe Platzbecker

https://doi.org/10.3324/haematol.2009.017749

Brief Reports

Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin

Damien R. Ashby, Daniel P. Gale, Mark Busbridge, Kevin G. Murphy, Neill D. Duncan, Tom D. Cairns, David H. Taube, Stephen R. Bloom, Frederick W.K. Tam, Richard Chapman, Patrick H. Maxwell, Peter Choi

https://doi.org/10.3324/haematol.2009.013136

Genetic modification of primary chronic lymphocytic leukemia cells with a lentivirus expressing CD38

Laurence Pearce, Liam Morgan, Thet Thet Lin, Saman Hewamana, R. James Matthews, Silvia Deaglio, Clare Rowntree, Christopher Fegan, Christopher Pepper, Paul Brennan

https://doi.org/10.3324/haematol.2009.014381