Abstract
In 20 patients with myeloid malignancies and isolated trisomy 11 an internal tandem duplication of the MLL and FLT3 genes was observed in 41% and 31% of the cases, respectively; 80% of the FLT3+ cases showed MLL self-fusion. Concomitant presence of MLL and FLT3 anomalies could be relevant in determining the poor outcome of patients with acute myeloid leukemia with trisomy 11.
Vol. 90 No. 2 (2005): February, 2005 : Letters to the Editor
Published By
Ferrata Storti Foundation, Pavia, Italy
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