Prolonged molecular remission after autologous stem cell transplantation in relapsed acute promyelocytic leukemia

Abstract

Six patients with relapsed acute promyelocytic leukemia (APL) received autologous stem cell transplantation (ASCT) in second (n=5) or fourth (n=1) molecular remission with a molecularly negative graft. After a median follow-up of 33 months from ASCT, 5 patients are alive in molecular remission and one died 27 months after autograft from refractory relapse.