We have observed some errors in the recently published manuscript “Lower incidence of chronic graft-versus-host disease after ruxolitinib plus extracorporeal photopheresis versus ruxolitinib alone in steroid-refractory acute graft-versus-host disease following allogeneic stem cell transplantationm”.1
The correct cumulative incidence of chronic graft-versus-host disease (cGvHD) and the 95% Confidence Interval (95%CI) in the Abstract need to be corrected in the Results section and in Table 4A.
- • In the Abstract, the 1-year cumulative incidence of cGvHD is correct as:
- Ruxolitinib: 49% (95%CI: 33-69%)
- Ruxolitinib + ECP: 24% (95%CI: 15-38%)
- • In the Results section, it is:
- Ruxolitinib: 41% (95%CI: 31-67%); this should be corrected to 49% (95%CI: 33-69%)
- Ruxolitinib + ECP: 24% (95%CI: 14-27%); this should be corrected to 24% (CI: 15-38%)
- • In Table 4A, the 1-year cumulative incidence of cGvHD is: Ruxolitinib: 51 (33-69); this should be corrected to 49 (33-69)
- Ruxolitinib + ECP: 25% (95%CI: 15-38%); this should be corrected to 24 (15-38).
Correct sentence of the Results section and the correct Table are shown below.
Chronic graft-versus-host disease, and chronic graft-versus-host disease, relapse-free survival and failure-free survival
At six and 12 months, 25% and 20% of evaluable patients in the Ruxo-ECP cohort and 20% and 66% of evaluable patients in the Ruxo cohort experienced cGvHD, resulting in a cumulative incidence of cGvHD at one year of 24% (95%CI: 15-38%) after Ruxo-ECP and 49% (95%CI: 33-69%) after Ruxo.
Correct Table 4.Outcome of steroid-refractory-acute graft-versus-host disease.
Footnotes
- Received November 3, 2025
- Accepted November 3, 2025
Correspondence
References
- I. Lastovytska, S. Heidenreich, E. Klyuchnikov. Lower incidence of chronic graft-versus-host disease after ruxolitinib plus extracorporeal photopheresis versus ruxolitinib alone in steroid-refractory acute graft-versus-host disease following allogeneic stem cell transplantation. Haematologica. 2025; 110(7):1536-1544. https://doi.org/10.3324/haematol.2024.286824Google Scholar
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