July, 2014
No. 99 (7)

Editorials

Review Articles

The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy

Graham Packham, Serge Krysov, Alex Allen, Natalia Savelyeva, Andrew J. Steele, Francesco Forconi, Freda K. Stevenson

https://doi.org/10.3324/haematol.2013.098384

Articles

Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis

Laurence C. Cheung, Deborah H. Strickland, Meegan Howlett, Jette Ford, Adrian K. Charles, Karen M. Lyons, David R. Brigstock, Roel Goldschmeding, Catherine H. Cole, Warren S. Alexander, Ursula R. Kees

https://doi.org/10.3324/haematol.2013.102327

Targeted shRNA screening identified critical roles of pleckstrin-2 in erythropoiesis

Baobing Zhao, Ganesan Keerthivasan, Yang Mei, Jing Yang, James McElherne, Piu Wong, John G. Doench, Gang Feng, David E. Root, Peng Ji

https://doi.org/10.3324/haematol.2014.105809

Aplastic Anemia

Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease

Clara Bueno, Mar Roldan, Eduardo Anguita, Damia Romero-Moya, Beatriz Martín-Antonio, Michael Rosu-Myles, Consuelo del Cañizo, Francisco Campos, Regina García, Maite Gómez-Casares, Jose Luis Fuster, Manuel Jurado, Mario Delgado, Pablo Menendez

https://doi.org/10.3324/haematol.2014.103580

A phase II multicenter rabbit anti-thymocyte globulin trial in patients with myelodysplastic syndromes identifying a novel model for response prediction

Rami S. Komrokji, Adam W. Mailloux, Dung-Tsa Chen, Mikkael A. Sekeres, Ronald Paquette, William J. Fulp, Chiharu Sugimori, Jennifer Paleveda-Pena, Jaroslaw P. Maciejewski, Alan F. List, Pearlie K. Epling-Burnette

https://doi.org/10.3324/haematol.2012.083345

Distinct clinical characteristics of myeloproliferative neoplasms with calreticulin mutations

Hajnalka Andrikovics, Tunde Krahling, Katalin Balassa, Gabriella Halm, Andras Bors, Magdalena Koszarska, Arpad Batai, Janos Dolgos, Judit Csomor, Miklos Egyed, Andrea Sipos, Peter Remenyi, Attila Tordai, Tamas Masszi

https://doi.org/10.3324/haematol.2014.107482

Efficacy and safety of radotinib in chronic phase chronic myeloid leukemia patients with resistance or intolerance to BCR-ABL1 tyrosine kinase inhibitors

Sung-Hyun Kim, Hari Menon, Saengsuree Jootar, Tapan Saikia, Jae-Yong Kwak, Sang-Kyun Sohn, Joon Seong Park, Seong Hyun Jeong, Hyeoung Joon Kim, Yeo-Kyeoung Kim, Suk Joong Oh, Hawk Kim, Dae Young Zang, Joo Seop Chung, Ho Jin Shin, Young Rok Do, Jeong-A Kim, Dae-Young Kim, Chul Won Choi, Sahee Park, Hye Lin Park, Gong Yeal Lee, Dae Jin Cho, Jae Soo Shin, Dong-Wook Kim

https://doi.org/10.3324/haematol.2013.096776

Safety and efficacy of switching to nilotinib 400 mg twice daily for patients with chronic myeloid leukemia in chronic phase with suboptimal response or failure on front-line imatinib or nilotinib 300 mg twice daily

Timothy P. Hughes, Andreas Hochhaus, Hagop M. Kantarjian, Francisco Cervantes, François Guilhot, Dietger Niederwieser, Philipp D. le Coutre, Gianantonio Rosti, Gert Ossenkoppele, Clarisse Lobo, Hirohiko Shibayama, Xiaolin Fan, Hans D. Menssen, Charisse Kemp, Richard A. Larson, Giuseppe Saglio

https://doi.org/10.3324/haematol.2013.091272

Pediatric posttransplant relapsed/refractory B-precursor acute lymphoblastic leukemia shows durable remission by therapy with the T-cell engaging bispecific antibody blinatumomab

Patrick Schlegel, Peter Lang, Gerhard Zugmaier, Martin Ebinger, Hermann Kreyenberg, Kai-Erik Witte, Judith Feucht, Matthias Pfeiffer, Heiko-Manuel Teltschik, Christina Kyzirakos, Tobias Feuchtinger, Rupert Handgretinger

https://doi.org/10.3324/haematol.2013.100073

Dexamethasone (6 mg/m2/day) and prednisolone (60 mg/m2/day) were equally effective as induction therapy for childhood acute lymphoblastic leukemia in the EORTC CLG 58951 randomized trial

Carine Domenech, Stefan Suciu, Barbara De Moerloose, Françoise Mazingue, Geneviève Plat, Alina Ferster, Anne Uyttebroeck, Nicolas Sirvent, Patrick Lutz, Karima Yakouben, Martine Munzer, Pierre Röhrlich, Dominique Plantaz, Frederic Millot, Pierre Philippet, Nicole Dastugue, Sandrine Girard, Hélène Cavé, Yves Benoit, Yves Bertrandfor, Children’s Leukemia Group (CLG) of the European Organisation for Research and Treatment of Cancer (EORTC)

https://doi.org/10.3324/haematol.2014.103507

Detection and outcome of occult leptomeningeal disease in diffuse large B-cell lymphoma and Burkitt lymphoma

Wyndham H. Wilson, Jacoline E.C. Bromberg, Maryalice Stetler-Stevenson, Seth M. Steinberg, Lourdes Martin-Martin, Carmen Muñiz, Juan Manuel Sancho, Maria Dolores Caballero, Marjan A. Davidis, Rik A. Brooimans, Blanca Sanchez-Gonzalez, Antonio Salar, Eva González-Barca, Jose Maria Ribera, Margaret Shovlin, Armando Filie, Kieron Dunleavy, Thomas Mehrling, Michele Spina, Alberto Orfao

https://doi.org/10.3324/haematol.2013.101741

Age is a prognostic factor even among patients with multiple myeloma younger than 66 years treated with high-dose melphalan: the IFM experience on 2316 patients

Marie-Lorraine Chretien, Benjamin Hebraud, Valérie Cances-Lauwers, Cyrille Hulin, Gerald Marit, Xavier Leleu, Lionel Karlin, Murielle Roussel, Anne-Marie Stoppa, Francois Guilhot, Thierry Lamy, Laurent Garderet, Brigitte Pegourie, Mamoun Dib, Catherine Sebban, Pascal Lenain, Sabine Brechignac, Bruno Royer, Marc Wetterwald, Laurence Legros, Frédérique Orsini-Piocelle, Laurent Voillat, Xavier Delbrel, Denis Caillot, Margaret Macro, Thierry Facon, Michel Attal, Philippe Moreau, Hervé Avet-Loiseau, Jill Corre

https://doi.org/10.3324/haematol.2013.098608

Clinical diagnosis and typing of systemic amyloidosis in subcutaneous fat aspirates by mass spectrometry-based proteomics

Julie A. Vrana, Jason D. Theis, Surendra Dasari, Oana M. Mereuta, Angela Dispenzieri, Steven R. Zeldenrust, Morie A. Gertz, Paul J. Kurtin, Karen L. Grogg, Ahmet Dogan

https://doi.org/10.3324/haematol.2013.102764

Recognition of adult and pediatric acute lymphoblastic leukemia blasts by natural killer cells

Giovanni F. Torelli, Nadia Peragine, Sara Raponi, Daria Pagliara, Maria S. De Propris, Antonella Vitale, Alice Bertaina, Walter Barberi, Lorenzo Moretta, Giuseppe Basso, Angela Santoni, Anna Guarini, Franco Locatelli, Robin Foà

https://doi.org/10.3324/haematol.2013.101931

Induction of A. fumigatus-specific CD4-positive T cells in patients recovering from invasive aspergillosis

Hetty Jolink, Renate S. Hagedoorn, Ellen L. Lagendijk, Jan W. Drijfhout, Jaap T. van Dissel, J.H. Frederik Falkenburg, Mirjam H.M. Heemskerk

https://doi.org/10.3324/haematol.2013.098830

Rituximab and three dexamethasone cycles provide responses similar to splenectomy in women and those with immune thrombocytopenia of less than two years duration

James B. Bussel, Christina S. Lee, Caroline Seery, Allison A. Imahiyerobo, Michaela V. Thompson, Diane Catellier, Ithamar G. Turenne, Vivek L. Patel, Paul A. Basciano, Rebecca L. Elstrom, Waleed Ghanima

https://doi.org/10.3324/haematol.2013.103291

Errata Corrige

Variations in non-pharmacological anti-infective measures in childhood leukemia – results of an international survey

Thomas Lehrnbecher, Richard Aplenc, Fernanda Rivas Pereira, Alvaro Lassaletta, Désirée Caselli, Jerzy Kowalczyk, Julia Chisholm, Lillian Sung

https://doi.org/10.3324/haematol.2014.112615

Online Only Articles

Clinical and biological characterization of patients with low (0.1–2%) JAK2V617F allele burden at diagnosis

Eric Lippert, Olivier Mansier, Marina Migeon, Barbara Denys, Asa Nilsson, Carolina Rosmond, Laurence Lodé, Valérie Ugo, Axelle Lascaux, Beatriz Bellosillo, Joaquin Martinez-Lopez, Dina Naguib, Nathalie Gachard, Nicolas Maroc, Sylvie Hermouet

https://doi.org/10.3324/haematol.2014.107656

Investigating the real role of HIF-1 and HIF-2 in iron recycling by macrophages

Jacques R.R. Mathieu, Mylène Heinis, Sara Zumerle, Stéphanie Delga, Agnès Le Bon, Carole Peyssonnaux

https://doi.org/10.3324/haematol.2013.102319

Red blood cell immunization in sickle cell disease: evidence of a large responder group and a low rate of anti-Rh linked to partial Rh phenotype

Monique Silvy, Christophe Tournamille, Jérôme Babinet, Sadaf Pakdaman, Sylvain Cohen, Jacques Chiaroni, Frédéric Galactéros, Philippe Bierling, Pascal Bailly, France Noizat-Pirenne

https://doi.org/10.3324/haematol.2014.104703

Hepcidin levels in Diamond-Blackfan anemia reflect erythropoietic activity and transfusion dependency

Dagmar Pospisilova, Dusan Holub, Zuzana Zidova, Lucie Sulovska, Jiri Houda, Vladimir Mihal, Ivana Hadacova, Lenka Radova, Petr Dzubak, Marian Hajduch, Vladimir Divoky, Monika Horvathova

https://doi.org/10.3324/haematol.2014.104034

Autologous stem cell transplantation after conditioning with yttrium-90 ibritumomab tiuxetan BEAM in refractory non-Hodgkin diffuse large B-cell lymphoma: results of a prospective, multicenter, phase II clinical trial

Javier Briones, Silvana Novelli, José A. García-Marco, José F. Tomás, Teresa Bernal, Carlos Grande, Miguel A. Canales, Antonio Torres, José M. Moraleda, Carlos Panizo, Isidro Jarque, Francisca Palmero, Miguel Hernández, Eva González-Barca, Dulce López, Dolores Caballero

https://doi.org/10.3324/haematol.2014.108308